keyword
MENU ▼
Read by QxMD icon Read
search

Femoral fracture

keyword
https://www.readbyqxmd.com/read/29167969/association-of-incident-hip-fracture-with-the-estimated-femoral-strength-by-finite-element-analysis-of-dxa-scans-in-the-osteoporotic-fractures-in-men-mros-study
#1
L Yang, N Parimi, E S Orwoll, D M Black, J T Schousboe, R Eastell
Finite element model can estimate bone strength better than BMD. This study used such a model to determine its association with hip fracture risk and found that the strength estimate provided limited improvement over the hip BMDs in predicting femoral neck (FN) fracture risk only. INTRODUCTION: Bone fractures occur only when it is loaded beyond its ultimate strength. The goal of this study was to determine the association of femoral strength, as estimated by finite element (FE) analysis of DXA scans, with incident hip fracture as a single condition or with femoral neck (FN) and trochanter (TR) fractures separately in older men...
November 22, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/29165039/determination-of-a-tissue-level-failure-evaluation-standard-for-rat-femoral-cortical-bone-utilizing-a-hybrid-computational-experimental-method
#2
Ruoxun Fan, Jie Liu, Zhengbin Jia, Ying Deng, Jun Liu
Macro-level failure in bone structure could be diagnosed by pain or physical examination. However, diagnosing tissue-level failure in a timely manner is challenging due to the difficulty in observing the interior mechanical environment of bone tissue. Because most fractures begin with tissue-level failure in bone tissue caused by continually applied loading, people attempt to monitor the tissue-level failure of bone and provide corresponding measures to prevent fracture. Many tissue-level mechanical parameters of bone could be predicted or measured; however, the value of the parameter may vary among different specimens belonging to a kind of bone structure even at the same age and anatomical site...
November 1, 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/29164558/rapamycin-facilitates-fracture-healing-through-inducing-cell-autophagy-and-suppressing-cell-apoptosis-in-bone-tissues
#3
Z-Y Yin, J Yin, Y-F Huo, J Yu, L-X Sheng, Y-F Dong
OBJECTIVE: To investigate the changes in cell autophagy and the molecular mechanism of rapamycin affecting the fracture healing. MATERIAL AND METHODS: Sprague-Dawley (SD) rats were used to establish the right femoral shaft fracture models, and then underwent immunofluorescence assay to detect the autophagy level in bone tissues. After model establishment, SD rats were divided into two groups, the control group and the rapamycin group (1 mg/kg/d). Respectively, at the 2nd, 4th, and 6th week, rats were randomly selected from each group for X-ray and Micro-computed tomography (Micro-CT) examinations to determine callus growth, immunofluorescence assay to detect the protein expression of light chain 3 II (LC3 II), immunohistochemistry to evaluate the autophagy level through detecting the expression of Beclin1 in rats, Western blotting assay to detect cell apoptosis in tissues, hematoxylin and eosin staining (HE staining) to evaluate the osteoblastic activity through count of osteoblast in bone tissue at the end of fracture, and measure the expression of vascular endothelial growth factors (VEGF)...
November 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29164532/correction-to-atraumatic-femoral-neck-fracture-during-bisphosphonate-treatment-case-report-and-review-of-the-literature
#4
Robert Wilk, Damian Kusz, Hanna Grygiel, Magdalena Grosiak, Jakub Kamiński, Marcin Kusz
Correction to: Aging Clin Exp Res https://doi.org/10.1007/s40520-017-0846-0.
November 21, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29164398/c-reactive-protein-levels-for-early-detection-of-early-postoperative-complications-after-proximal-femoral-fracture-surgery
#5
Romain Schutz, Baptiste Boukebous, Pierre Boutroux, Pascal Guillon
INTRODUCTION: We have studied the early C-reactive protein (CRP) kinetics after proximal femoral fracture (PFF) surgery and defined a chart of CRP threshold values beyond which early postoperative complications are likely. MATERIALS AND METHODS: We have prospectively followed up a 42-patient cohort for surgical treatment by osteosynthesis or hip arthroplasty, and CRP was dosed at admission, on day 1, day 3, day 5 and then twice weekly for 30 days at the same time as a platelet count control of low molecular weight heparins...
November 21, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29162931/comparison-of-clinical-outcomes-with-intertan-vs-gamma-nail-or-pfna-in-the-treatment-of-intertrochanteric-fractures-a-meta-analysis
#6
Jian-Xiong Ma, Ming-Jie Kuang, Zheng-Rui Fan, Fei Xing, Yun-Long Zhao, Lu-Kai Zhang, Heng-Ting Chen, Chao Han, Xin-Long Ma
Intertrochanteric fractures are common injuries in the elderly. Conventional intramedullary nails including Gamma 3 locking nail and proximal femoral nail antirotation (PFNA) were designed for unstable intertrochanteric fractures. The InterTan (IT) nail system, introduced in 2005, has been reported superior biomechanical and clinical outcomes compared with 1-screw nailing system. However, some recent studies have reported that IT did not improve functional recovery in patients with intertrochanteric fractures...
November 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29162265/the-impact-of-antegrade-intramedullary-nailing-start-site-using-the-sign-nail-in-proximal-femoral-fractures-a-prospective-cohort-study
#7
Mohamed Mustafa Diab, Hao-Hua Wu, Edmund Eliezer, Billy Haonga, Saam Morshed, David W Shearer
INTRODUCTION: In many low and middle-income countries (LMICs) SIGN nail is commonly used for antegrade femoral intramedullary (IM) nailing, using a start site either at the tip of the greater trochanter or piriformis fossa. While a correct start site is considered an essential technical step; few studies have evaluated the impact of using an erroneous start site. This is particularly relevant in settings with limited access to fluoroscopy to aid in creating a nail entry point. The purpose of this study was to evaluate the impact of antegrade SIGN IM nailing start site on radiographic alignment and health-related quality of life...
November 18, 2017: Injury
https://www.readbyqxmd.com/read/29162246/floating-hip-and-associated-injuries
#8
Plácido Zamora-Navas, Francisco Javier Estades-Rubio, Juan Ramón Cano, Enrique Guerado
AIM: To describe our experience in treating patients diagnosed with floating hip injury and to communicate the outcomes achieved and the rate of complications. A secondary aim is to compare the results of this group in terms of quality of life with those of patients presenting with a fracture either of the pelvis or of the acetabulum, but in which the femoral segment is not involved. PATIENTS AND METHODS: This is a descriptive study of the patients diagnosed with floating hip injury (25 patients) who were treated at our hospital between 2004 and 2007, with a minimum follow-up of seven years...
November 2017: Injury
https://www.readbyqxmd.com/read/29162245/ultrasound-guided-supra-acetabular-pin-placement-in-pelvic-external-fixation-description-of-a-surgical-technique-and-results
#9
Francisco Chana-Rodríguez, Manuel Cuervas-Mons, José Rojo-Manaute, Félix Mora, Juan Arnal, Javier Vaquero-Martín
INTRODUCTION: Pelvic fracture in trauma patients can lead to hemodynamic instability. External fixation is a treatment capable of stabilizing these injuries in the context of damage control surgery. Supra-acetabular pin offers the greater biomechanical stability but requires the use of intraoperative fluoroscopy. The aim of this study was to analyze our results for an ultrasound-guided supra-acetabular pinning. MATERIAL AND METHODS: Cross-sectional study with cadaveric specimens...
November 2017: Injury
https://www.readbyqxmd.com/read/29162241/influence-of-screw-combination-and-nail-materials-in-the-stability-of-anterograde-reamed-intramedullary-nail-in-distal-femoral-fractures
#10
Sergio Gabarre, Jorge Albareda, Luis Gracia, Sergio Puértolas, Elena Ibarz, Antonio Herrera
Intramedullary nailing (IM) is a technique universally accepted to treat femoral diaphyseal fractures. The treatment of fractures located in the distal third remains a controversial issue though. A finite element model of the femur has been developed, analyzing distal fractures with several gap sizes combined with different interlocking combinations of distal screws with one oblique screw proximally to stabilize the intramedullary nail. The mechanical strength of the nail against bending and compression efforts was also studied...
November 2017: Injury
https://www.readbyqxmd.com/read/29162240/influence-of-gap-size-screw-configuration-and-nail-materials-in-the-stability-of-anterograde-reamed-intramedullary-nail-in-femoral-transverse-fractures
#11
Sergio Gabarre, Jorge Albareda, Luis Gracia, Sergio Puértolas, Elena Ibarz, Antonio Herrera
Femoral shaft fractures are among the most severe injuries of the skeleton. They are associated with high morbidity and mortality. The most appropriate treatment depending on the type of fracture and location level should be chosen. A finite element model of the femur has been developed, analyzing various types of fractures in the subtrochanteric and diaphyseal supracondylar area, with several gap sizes, being stabilized with a single combination of screws for the intramedullary nail. The mechanical strength of the nail against bending and compression efforts was studied comparing two materials for the nail: stainless steel and titanium alloy...
November 2017: Injury
https://www.readbyqxmd.com/read/29162229/design-of-experiments-confirms-optimization-of-lithium-administration-parameters-for-enhanced-fracture-healing
#12
Kathak Vachhani, Andrea Pagotto, Yufa Wang, Cari Whyne, Diane Nam
Fracture healing is a lengthy process which fails in 5-10% of cases. Lithium, a low-cost therapeutic used in psychiatric medicine, up-regulates the canonical Wingless pathway crucial for osteoblastic mineralization in fracture healing. A design-of-experiments (DOE) methodology was used to optimize lithium administration parameters (dose, onset time and treatment duration) to enhance healing in a rat femoral fracture model. In the previously completed first stage (screening), onset time was found to significantly impact healing, with later (day 7 vs...
October 28, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29162067/necrotizing-fasciitis-after-high-dose-rate-brachytherapy-and-external-beam-radiation-for-prostate-cancer-a-case-report
#13
Shimpei Yamashita, Yasuo Kohjimoto, Akinori Iba, Kazuro Kikkawa, Isao Hara
BACKGROUND: In recent years, the delayed side effects associated with radiotherapy for prostate cancer have drawn the interest of urologists. Although urosymphyseal fistula is one of these delayed side effects, this serious complication is rarely described in literature and is poorly recognized. CASE PRESENTATION: We report our experience in treating a 77-year-old male patient with necrotizing fasciitis after high-dose rate brachytherapy plus external beam radiation for prostate cancer...
November 21, 2017: BMC Urology
https://www.readbyqxmd.com/read/29160896/influence-of-fracture-stability-on-staphylococcus-epidermidis-and-staphylococcus-aureus-infection-in-a-murine-femoral-fracture-model
#14
M Sabaté Brescó, L O'Mahony, S Zeiter, K Kluge, M Ziegler, C Berset, D Nehrbass, R G Richards, T F Moriarty
Fracture-related infection (FRI) is a major complication in surgically fixed fractures. Instability of the fracture after fixation is considered a risk factor for infection; however, few experimental data are available confirming this belief. To study whether stable fractures led to higher infection clearance, mouse femoral osteotomies were fixed with either stable or unstable fixation and the surgical site was contaminated with either Staphylococcus epidermidis (S. epidermidis)or Staphylococcus aureus (S. aureus)clinical isolates...
November 21, 2017: European Cells & Materials
https://www.readbyqxmd.com/read/29159533/reduced-bone-mineral-density-in-human-immunodeficiency-virus-infected-individuals-a-meta-analysis-of-its-prevalence-and-risk-factors
#15
S S L Goh, P S M Lai, A T B Tan, S Ponnampalavanar
A meta-analysis was conducted to evaluate the prevalence of osteopenia/osteoporosis in human immunodeficiency virus (HIV)-infected individuals. The prevalence of osteopenia/osteoporosis in HIV-infected and antiretroviral therapy (ART)-treated individuals was significantly higher than respective controls. Evidence regarding bone loss within first year of HIV infection or ART initiation was preliminary. PURPOSE: The aim of the study is to systematically review published literature on the prevalence of osteopenia/osteoporosis and its associated risk factors in HIV-infected individuals...
November 20, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/29157842/femoral-intertrochanteric-nail-fitn-a-new-short-version-design-with-an-anterior-curvature-and-a-geometric-match-study-using-post-operative-radiographs
#16
Shi-Min Chang, Sun-Jun Hu, Zhuo Ma, Shou-Chao Du, Ying-Qi Zhang
OBJECTIVE: Femoral intertrochanteric fractures are usually fixed with short, straight cephalomedullary nails. However, mismatches between the nail and the femur frequently occur, such as tip impingement and tail protrusion. The authors designed a new type of short femoral intertrochanteric nail (fitn) with an anterior curvature (length=19.5cm, r=120cm) and herein report the geometric match study for the first of 50 cases. METHODS: A prospective case series of 50 geriatric patients suffering from unstable intertrochanteric fractures (AO/OTA 31 A2/3) were treated...
November 17, 2017: Injury
https://www.readbyqxmd.com/read/29157107/the-impact-of-surgery-for-trochanteric-femur-fracture-on-sexuality-in-men-and-their-female-partners
#17
Melih Balci, Deniz Cankaya, Altug Tuncel, Burak Yoldas, Ozer Guzel, Cagdas Senel
PURPOSE: This study was aimed to investigate the effects of trochanteric femur fracture treatment methods on erectile functions of the patients and on sexual functions with their female partners. MATERIALS AND METHODS: A total of 43 patients with trochanteric femur fracture who underwent proximal femoral nail (PFN) or proximal femur locking compression plate (PF-LCP) surgery were included in the study. The PFN implant was applied to group 1 ( n = 23) and the PF-LCP implant to group 2 ( n = 20)...
September 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/29155868/tocilizumab-potentially-prevents-bone-loss-in-patients-with-anticitrullinated-protein-antibody-positive-rheumatoid-arthritis
#18
Yi-Ming Chen, Hsin-Hua Chen, Wen-Nan Huang, Tsai-Ling Liao, Jun-Peng Chen, Wen-Cheng Chao, Ching-Tsai Lin, Wei-Ting Hung, Chia-Wei Hsieh, Tsu-Yi Hsieh, Yi-Hsing Chen, Der-Yuan Chen
Rheumatoid arthritis (RA) is associated with a high risk of osteoporosis and fracture. Interleukin (IL)-6 inhibitors may suppress osteoclast activation. Anticitrullinated protein antibody (ACPA) titers are inversely associated with bone mineral density (BMD). However, the differential effect of ACPA on bone turnover marker (BTM) and BMD changes after IL-6 inhibition remains unclear. This prospective study recruited patients with active RA with inadequate response to methotrexate or biologics. BMD was measured before and after 2-year tocilizumab (TCZ) treatment...
2017: PloS One
https://www.readbyqxmd.com/read/29155725/an-efficient-and-reproducible-protocol-for-distraction-osteogenesis-in-a-rat-model-leading-to-a-functional-regenerated-femur
#19
Martine Pithioux, Flavy Roseren, Christian Jalain, Franck Launay, Philippe Charpiot, Patrick Chabrand, Sandrine Roffino, Edouard Lamy
This protocol describes the use of a newly developed external fixator for distraction osteogenesis in a rat femoral model. Distraction osteogenesis (DO) is a surgical technique leading to bone regeneration after an osteotomy. The osteotomized extremities are moved away from each other by gradual distraction to reach the desired elongation. This procedure is widely used in humans for lower and upper limb lengthening, treatment after a bone nonunion, or the regeneration of a bone defect following surgery for bone tumor excision, as well as in maxillofacial reconstruction...
October 23, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29154969/adults-with-cystic-fibrosis-have-deficits-in-bone-structure-and-strength-at-the-distal-tibia-despite-similar-size-and-measuring-standard-and-relative-sites
#20
Kyle K Nishiyama, Sanchita Agarwal, Anna Kepley, Fernando Rosete, Yizhong Hu, X Edward Guo, Claire L Keating, Emily A DiMango, Elizabeth Shane
Individuals with cystic fibrosis (CF) have lower bone mineral density (BMD) by DXA and are at higher risk of fracture than healthy controls. However, the 2-dimensional measurement of areal BMD (aBMD) provided by DXA is influenced by bone size and the true extent of the bone deficit is unclear. Our objective was to use high-resolution peripheral quantitative computed tomography (HR-pQCT) and individual trabecula segmentation (ITS) analysis to compare volumetric BMD (vBMD), microarchitecture and estimated strength at the distal radius and tibia in 26 young adults with CF and 26 controls matched for age, gender, and race...
November 14, 2017: Bone
keyword
keyword
116876
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"