Karine Robitaille, Marie-Hélène Guertin, Afshin Jamshidi, Hui Wen Xu, Hélène Hovington, Jean-François Pelletier, Lisanne Beaudoin, Nikunj Gevariya, Louis Lacombe, Rabi Tiguert, Yves Caumartin, Thierry Dujardin, Paul Toren, Michele Lodde, Étienne Racine, Dominique Trudel, Martine Perigny, Thierry Duchesne, Josée Savard, Pierre Julien, Yves Fradet, Vincent Fradet
BACKGROUND: High prostate eicosapentaenoic fatty acid (EPA) levels were associated with a significant reduction of upgrading to grade group (GG) ≥ 2 prostate cancer in men under active surveillance. We aimed to evaluate the effect of MAG-EPA long-chain omega-3 fatty acid dietary supplement on prostate cancer proliferation. METHODS: A phase II double-blind randomized placebo-controlled trial was conducted in 130 men diagnosed with GG ≥ 2 prostate cancer and undergoing radical prostatectomy between 2015-2017 (Clinicaltrials...
March 22, 2024: Commun Med (Lond)