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arthritis in nigeria

Girish M Mody
Africa faces many health challenges despite sustained growth and development over the past decade. Contributory factors are the lack of financial resources, an inadequate health professional workforce, a high burden of communicable diseases, and an increasing burden of non-communicable diseases. Rheumatology services are limited or non-existent in many parts of sub-Saharan Africa. Over the past decade, partnerships with international academic institutions have resulted in some progress in the training of rheumatologists and health professionals and development of rheumatology services in countries such as Kenya, Nigeria, and Zambia...
March 7, 2017: Arthritis Research & Therapy
Babatunde Hakeem Olaosebikan, Olufemi Oladipo Adelowo, Barakat Adeola Animashaun, Richard Oluyinka Akintayo
BACKGROUND: Paediatric rheumatology service in Sub-Sahara African is virtually not available as there is a shortage of paediatric rheumatologists and other rheumatology health professionals. We aim to describe the clinical spectrum and the frequencies of paediatric rheumatic diseases (PRDs) in Lagos State University Teaching Hospital (LASUTH), Lagos, Nigeria. METHODS: This is a retrospective review of patients with PRDs seen over a five year period (March 2010 to February 2016) at the rheumatology clinic and children ward of LASUTH...
January 31, 2017: Pediatric Rheumatology Online Journal
B O Adefuye, O O Adelowo, P O Adefuye, O O Oguntona
Rheumatoid arthritis may sometimes present with extra-articular involvement, pulmonary involvement is not common. Rheumatoid arthritis has been reported among Nigerians and extra-articular manifestations are rarely seen. One of the patients was misdiagnosed and mismanaged as a patient with pulmonary tuberculosis. The study is to demonstrate that rheumatoid arthritis is not as rare as previously reported in Nigeria and its pulmonary involvement can mimic tuberculosis or other granulomatous lung disorder. Clinical and serological acumen are necessary to distinguish between the two...
September 2014: East African Medical Journal
B O Adefuye, O O Adelowo, P O Adefuye, O O Oguntona
Rheumatoid arthritis may sometimes present with extra-articular involvement, pulmonary involvement is not common. Rheumatoid arthritis has been reported among Nigerians and extra-articular manifestations are rarely seen. One of the patients was misdiagnosed and mismanaged as a patient with pulmonary tuberculosis. The study is to demonstrate that rheumatoid arthritis is not as rare as previously reported in Nigeria and its pulmonary involvement can mimic tuberculosis or other granulomatous lung disorder. Clinical and serological acumen are necessary to distinguish between the two...
September 2014: East African Medical Journal
Wasiu O Adebimpe, Olubukunola Omobuwa, Akinlolu G Omisore, Oluwatosin Adeoye
OBJECTIVES: This study assessed obesity indices and pattern of arthritis among elderly women in Osun State, Southwestern Nigeria. METHODS: The cross-sectional descriptive study was carried out among 350 elderly women selected by multistage sampling technique. Research instruments used in data collection were semi-structured, interviewer-administered pre-tested questionnaires that were analyzed using the Statistical Package for Social Sciences software version 17...
2015: SAGE Open Medicine
A O Aderibige, O I Agboola, A T Eduviere
BACKGROUND: Struchium sparganophora is a medicinal herb useful in the treatment of pain, fever, arthritis, rheumatism, neurological and mental disorders in traditional system of medicine in Nigeria and some other African countries. This study was carried out to evaluate the anti-inflammatory and analgesic properties of Struchium sparganophora in mice. METHODS: The anti-inflammatory effect of Struchium sparganophora was evaluated using; carrageenan-induced paw oedema and histamine-induced paw oedema in mice...
March 2015: African Journal of Medicine and Medical Sciences
Odarosa Magdiel Uhumwangho, Rita Omoso Momoh
BACKGROUND: Central serous chorioretinopathy (CSCR) is a retinal cause of visual loss. The aim of this report is to describe the pattern of presentation of CSCR in patients presenting to a tertiary hospital in Nigeria within a specified period. MATERIALS AND METHODS: The case folders of all patients in which a diagnosis of central serous retinopathy (CSR) was made from January 1, 2012 to December 31, 2014 were retrieved, data extracted and reviewed. RESULTS: There were a total of five patients within the study period made of four males and one female...
October 2015: Annals of African Medicine
Manjusha Choudhary, Vipin Kumar, Hitesh Malhotra, Surender Singh
ETHNO PHARMACOLOGICAL RELEVANCE: Traditional medicinal plants are practiced worldwide for treatment of arthritis especially in developing countries where resources are meager. This review presents the plants profiles inhabiting throughout the world regarding their traditional usage by various tribes/ethnic groups for treatment of arthritis. MATERIALS AND METHODS: Bibliographic investigation was carried out by analyzing classical text books and peer reviewed papers, consulting worldwide accepted scientific databases from the last six decades...
April 2015: Journal of Intercultural Ethnopharmacology
Chinaka O Nwaehujor, Rita I Udegbunam, Julius O Ode, Onyeka V Asuzu
BACKGROUND: Ethnopharmacological practitioners in Nigeria have used aqueous and ethanol extracts of Bridelia micrantha leaves to manage conditions associated with inflammation, and these include diabetes, chest pain, edema, arthritis and joint pains. This study aimed to evaluate the effects of methanol leaf extract of B. micrantha on chronic inflammation and oxidative stress which accompany diabetic conditions, in streptozotocin-induced diabetic Albino Wistar rats. METHODS: The dried leaves were extracted by percolation in 80% methanol:water for 72 h after which the mixture was filtered using Whatman No...
December 2015: Journal of Complementary & Integrative Medicine
Frances O A Ajose, Olufemi Adelowo, Olufemi Oderinlo
BACKGROUND: Behçet's disease (BD) is a chronic, multisystem, inflammatory pan-vasculitis of unknown etiology, with heterogeneous presentations in different parts of the world. It commonly involves the mucosae, skin, joints, eyes, and central nervous system. Behçet's disease is considered to represent an autoimmune reaction triggered by a yet to be identified infectious agent in a genetically predisposed person. It most commonly affects persons of Mediterranean or Far Eastern origin and is considered rare among Black Africans...
August 2015: International Journal of Dermatology
Dd Mue, Mn Salihu, Fo Awonusi, Wt Yongu, Jn Kortor, Ic Elachi
BACKGROUND: Septic arthritis is an acute bacterial infection affecting synovial joints. It is an orthopaedic emergency with potential high morbidity and mortality. This study determined the epidemiological pattern and outcome of acute septic arthritis and analyzed factors affecting morbidity and mortality Methods:This is a 5 year (2007-2012) retrospective study conducted at NKST rehabilitation hospital Mkar, North -Central Nigeria. All patients with septic arthritis upon presentation were consecutively selected...
January 2013: Journal of the West African College of Surgeons
Adejuwon Adewale Adeneye, Adekunle Ibrahim Oreagba, Ismail Ogunbayode Ishola, Hassanat Adeola Kalejaiye
BACKGROUND: Different decoctions of Alchornea cordifolia leaves are used by Yoruba herbalists (Southwest Nigeria) for the local treatment of ulcers, rheumatic pains, febrile convulsions, and for enhancing physical performance. MATERIALS AND METHODS: In this study, the anti-arthritic effect of 100 - 400 mg/kg/day of the hydroethanolic leaf extract of Alchornea cordifolia (HEAC) was investigated in Complete Freund's Adjuvant (CFA)-induced arthritic rats as a way of evaluating its efficacy in the local management of arthritis...
2014: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
Mathew Sunday Jenyo, James Olusegun Bamidele, Wasiu Olalekan Adebimpe
BACKGROUND: Arthritis is a common presentation among Nigerians, most especially in the elderly population. Easy access to over-the-counter drugs, paucity of data, and non-orthodox medical practice have underscored the need to examine the magnitude of the problem toward morbidity reduction risk factors. The objective of the study was to determine the pattern of arthralgia in Osogbo community in Southwestern Nigeria. MATERIALS AND METHODS: This was a descriptive cross-sectional study conducted between September 2010 and August 2011...
April 2014: Annals of African Medicine
M Peil, A Bamisaiye, S Ekpenyong
This paper examines the help which elderly Nigerians get in the form of services from family, relatives and non-relatives and the effect of their age, sex, location (urban/rural) and state of health on the provision of these services. Children are by far the most important source of services, followed by grandchildren. Few old people have neither children nor grandchildren available to help them. Lack of household help was more common for women than for men and women were more likely than men to carry on with domestic tasks into extreme old age...
April 1989: Journal of Cross-cultural Gerontology
Chinenye J Ugwah-Oguejiofor, Kabiru Abubakar, Michael O Ugwah, Anoka A Njan
ETHNOPHARMACOLOGICAL RELEVANCE: Caralluma dalzielii has been used for treating several ailments including convulsion, leprosy, snake bites, otitis (ear pain), fungal diseases and rheumatoid arthritis in Northern Nigeria. However there is no scientific evidence to support its use in literature. To evaluate the antinociceptive and anti-inflammatory properties of the aqueous extract of Caralluma dalzielii in animal models. MATERIALS AND METHODS: The antinociceptive and anti-inflammatory properties were assessed using acetic acid induced writhing test in mice, sub plantar formalin induced nociception, the tail-flick test and formalin induced oedema in rats...
December 12, 2013: Journal of Ethnopharmacology
Jacob O Popoola, Olawole O Obembe
ETHNO-PHARMACOLOGICAL RELEVANCE: All parts of Moringa oleifera are medicinally valuable with overlapping uses in treating myriads of ailments and diseases including body pains and weakness, fever, asthma, cough, blood pressure, arthritis, diabetes, epilepsy, wound, and skin infection. Moringa also has robust ability to challenge terminal diseases such as HIV/AIDs infections, chronic anemia, cancer, malaria and hemorrhage. The present study was to obtain ethnobotanical information on the use and local knowledge variation, geographical distribution, and to collect different landraces of Moringa oleifera from the different agro-ecological regions in Nigeria, for further studies...
November 25, 2013: Journal of Ethnopharmacology
Abimbola Sowemimo, Femi Samuel, Muyiwa Samuel Fageyinbo
ETHNOPHARMACOLOGICAL RELEVANCE: The leaves of Markhamia tomentosa (Benth.) K. Schum (Bignoniaceae) are used traditionally for the treatment of oedema and rheumatoid arthritis in Nigeria. AIM OF THE STUDY: The aim of the work was to investigate the anti-inflammatory activity of the ethanolic leaf extract of Markhamia tomentosa. MATERIALS AND METHODS: The extract was screened using the carrageenan-induced paw oedema in rats, xylene-induced oedema in mice and the formalin-induced oedema in mice at 50, 100, 200mg/kg doses p...
August 26, 2013: Journal of Ethnopharmacology
David D Obiri, Newman Osafo
ETHNOPHARMACOLOGICAL RELEVANCE: Xylopia aethiopica has been traditionally used in the form of the dried fruit decoction to treat bronchitis, asthma, arthritis and rheumatism in Ghana, Nigeria and Cameroon. Aim of the study is to evaluate the anti-anaphylactic and anti-inflammatory effects of a 70% aqueous ethanol extract of the fruits of Xylopia aethiopica. MATERIALS AND METHODS: Systemic anaphylaxis was induced by the injection of either compound 48/80 or lipopolysaccharide, LPS and survival rates of mice monitored for 1 h or 7 days respectively while IgE-mediated anaphylaxis in a local allergic reaction was studied in the pinnal inflammation model in mice...
July 30, 2013: Journal of Ethnopharmacology
Frances O A Ajose
BACKGROUND: African hair in its natural state poses tenacious grooming challenges; consequently a large portion of the African cosmetic industry is focused on means to relax the tight curls of African hair to make the hair more manageable. In malnourished and hypoproteinemic states, African hair straightens in an uncomplimentary manner. Recently, we observed that in certain diseases African hair changes to a desirable silky wavy texture. METHOD: To identify the diseases that turn African hair silky and their parameters we examined 5612 dermatology patients at a tertiary hospital in Nigeria...
November 2012: International Journal of Dermatology
J P Ambe, Y Mava, R Chama, G Farouq, Y Machoko
BACKGROUND: Sickle cell disease (SCD) is a more common and severe disease in Africa. Nigeria the most populous black nation in Africa has the largest number of sickle cell anaemia (SCA) patients in the world. Borno and Yobe State has the largest number of sickle cell trait in Nigeria with prevalence of 27.9% and 32.6% respectively. Sickle cell anaemia survival to adulthood in Africa was reported to be 10-15% in the first decade of life, with the death rate of about 5% during subsequent decades...
April 2012: West African Journal of Medicine
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