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https://www.readbyqxmd.com/read/29781881/individual-and-network-factors-associated-with-hiv-care-continuum-outcomes-among-nigerian-msm-accessing-healthcare-services
#1
Habib O Ramadhani, Nicaise Ndembi, Rebecca G Nowak, Uchenna Ononaku, Jerry Gwamna, Ifeanyi Orazulike, Sylvia Adebajo, Trevor A Crowell, Hongjie Liu, Stefan D Baral, Julie Ake, Man E Charurat
BACKGROUND: and setting: As data on the determinants of the HIV care continuum from key populations such as men who have sex with men (MSM) in resource-limited, settings (RLS) are limited, the study aimed to characterize HIV care continuum outcomes and assess individual and network barriers to progression through the HIV care continuum among MSM in Abuja and Lagos, Nigeria. METHODS: TRUST/RV368 study used respondent-driven-sampling to accrue MSM into community-based clinics in Nigeria...
May 16, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29742119/prior-subclinical-histoplasmosis-revealed-in-nigeria-using-histoplasmin-skin-testing
#2
Rita O Oladele, Conchita Toriello, Folasade T Ogunsola, Olusola O Ayanlowo, Philip Foden, Adetona S Fayemiwo, Iriagbonse I Osaigbovo, Anthony A Iwuafor, Shuwaram Shettima, Halimat A Ekundayo, Malcolm D Richardson, David W Denning
OBJECTIVES: Disseminated histoplasmosis is an AIDS-defining illness. Histoplasmosis is commonly misdiagnosed as tuberculosis. Nigeria has the second highest number of people living with HIV/AIDS in Africa. The present study was carried out to investigate the prevalence of skin sensitivity amongst Nigerians to histoplasmin. DESIGN: A cross-sectional study was conducted in six centres across five geopolitical zones of Nigeria. METHODS: We recruited both healthy non-HIV and HIV-positive adults with CD4 count ≥ 350 cells/mm3 regardless of their ART status from March to May 2017...
2018: PloS One
https://www.readbyqxmd.com/read/29676341/the-prevalence-and-risk-factors-for-trichomonas-vaginalis-infection-amongst-human-immunodeficiency-virus-infected-pregnant-women-attending-the-antenatal-clinics-of-a-university-teaching-hospital-in-lagos-south-western-nigeria
#3
Olaolopin Ijasan, Kehinde Sharafadeen Okunade, Ayodeji Ayotunde Oluwole
Background: Trichomonas vaginalis infection is the most prevalent non-viral sexually transmitted infection worldwide. Interactions between this infection and human immunodeficiency virus (HIV) may cause adverse pregnancy outcomes such as preterm labour, premature rupture of membranes, chorioamnionitis, low birth weight and post-abortal sepsis. Aims: This study was aimed to determine the prevalence and risk factors of T. vaginalis infection amongst HIV-positive pregnant women attending antenatal care at the Lagos University Teaching Hospital (LUTH), Lagos, Nigeria...
January 2018: Nigerian Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29660833/selenium-deficiency-and-pregnancy-outcome-in-pregnant-women-with-hiv-in-lagos-nigeria
#4
Kehinde S Okunade, Olusola F Olowoselu, Gbemisola E Osanyin, Sarah John-Olabode, Sulaimon A Akanmu, Rose I Anorlu
OBJECTIVE: To investigate the prevalence of maternal selenium deficiency and its effects on pregnancy outcomes in pregnant women with HIV in Lagos, Nigeria. METHODS: The present descriptive cross-sectional study enrolled women aged 15-49 years with HIV who were at 14-26 weeks of a singleton pregnancy and were attending Lagos University Teaching Hospital, Lagos, Nigeria, between August 1, 2016, and April 30, 2017. Participants were selected by consecutive sampling and baseline data were collected through interviews...
April 16, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29617437/patient-nominated-supporters-as-facilitators-for-engagement-in-hiv-care-in-a-referral-hospital-in-peru-a-retrospective-cohort-study
#5
Mateo Prochazka, Larissa Otero, Kelika A Konda, Elsa González-Lagos, Juan Echevarría, Eduardo Gotuzzo
Patient-nominated supporters can potentially improve the continuum of HIV care. We retrospectively determined factors associated with having a patient-nominated supporter among people living with HIV (PLWH), and its association with retention in care and viral suppression. We analysed registries of adults evaluated by social workers (n = 1345) at a referral hospital in Peru between 2011-2014. Nondisclosure of HIV status was associated with lacking supporters (aPR: 5.41, 95% CI: 3.83-7.64). Retention in care was 76...
2018: PloS One
https://www.readbyqxmd.com/read/29378902/asymptomatic-lymphogranuloma-venereum-among-nigerian-men-who-have-sex-with-men
#6
Trevor A Crowell, Justin Hardick, Kara Lombardi, Zahra Parker, Afoke Kokogho, Senate Amusu, Sunday Odeyemi, Andrew Ivo, Stefan D Baral, Rebecca G Nowak, Sylvia Adebajo, Manhattan E Charurat, Julie Ake, Charlotte A Gaydos
OBJECTIVES: Recent outbreaks of anorectal lymphogranuloma venereum (LGV) among men who have sex with men (MSM) have been characterised by proctocolitis requiring extended antibiotic treatment compared with infections caused by other serovars of Chlamydia trachomatis (CT). We describe the prevalence and clinical features of LGV among Nigerian MSM diagnosed with anorectal CT. METHODS: MSM were recruited for this observational cohort in Lagos, Nigeria, using respondent-driven sampling and screened for HIV and bacterial STIs every three months for up to 18 months...
January 29, 2018: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29374399/sonographic-evaluation-of-kidney-echogenicity-and-morphology-among-hiv-sero-positive-adults-at-lagos-university-teaching-hospital
#7
Cletus Uche Eze, Charles Ugwoke Eze, Adekunle Adeyomoye
AIM: To evaluate the role of kidney echogenicity and morphology in the diagnosis of human immunodeficiency virus-associated nephropathy (HIVAN). SUBJECTS AND METHODS: In the cross-sectional study, a sample of 340 anti-retroviral therapy (ART)-naïve AIDS patients underwent laboratory CD4+ count, serum creatinine determination and sonographic renal echogenicity grading and size measurement. Rounded kidneys were described as bulbous while bean-shaped kidneys were described as reniform; echogenicity was categorized into grades 0, 1, 2 and 3...
March 2018: Journal of Ultrasound
https://www.readbyqxmd.com/read/29298172/psoriatic-arthritis-in-nigeria-case-series-and-literature-review
#8
Akpabio Akanimo Akpabio, Babatunde Hakeem Olaosebikan, Olufemi Oladipo Adelowo
BACKGROUND: Psoriatic arthritis (PsA) is an extracutaneous manifestation of psoriasis occurring in 6% to 42% of patients. Both conditions are common among whites but rarely reported among black Africans.Few African studies, however, have reported PsA frequencies of 0% to 4.6%, with a previous case report of 2 patients from a Nigerian rheumatology clinic. METHODS: Case records of PsA patients from the Lagos State University Teaching Hospital Rheumatology Clinic seen over a 5-year period from January 2012 to December 2016 were retrieved and documented...
January 3, 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29210470/variable-implementation-of-sexuality-education-in-three-nigerian-states
#9
Michael O N Kunnuji, Rachel Sullivan Robinson, Yusra Ribhi Shawar, Jeremy Shiffman
In 2003, Nigeria adopted the Family Life and HIV Education (FLHE) sexuality education curriculum. Our analysis interrogates variation in sub-national implementation. We conducted 52 interviews with persons knowledgeable about the curriculum in three states-Kano, Lagos, and Niger-and reviewed publications on FLHE. In Kano, the socio-cultural context impeded implementation, but the persistence of innovative local champions resulted in some success. In Lagos, the cosmopolitan context, effective champions, funding by international donors, and a receptive government bureaucracy led to successful implementation...
December 2017: Studies in Family Planning
https://www.readbyqxmd.com/read/29179657/psychosocial-factors-predicting-risky-sexual-behaviour-among-long-distance-truck-drivers-in-lagos-nigeria
#10
Abiodun Musbau Lawal, Benjamin Oladapo Olley
Long distance truck drivers (LDTDs) have been identified as one of the groups at higher risk for human immunodeficiency virus (HIV) infection. Understanding how certain social and psychological variables that have a strong theoretical basis contribute to sexual risk behaviour will guide in the implementation process of HIV risk-reduction intervention in the trucking population. In line with the conceptualisation of Information, Motivation and Behavioural skills model, we examined the extent that HIV knowledge, attitude towards condom use, peer support to condom use, perceived vulnerability to HIV/AIDS, and condom use self-efficacy will independently and jointly explain sexual risk behaviours of LDTDs in a haulage company in Lagos, Nigeria...
December 2017: SAHARA J: Journal of Social Aspects of HIV/AIDS Research Alliance
https://www.readbyqxmd.com/read/29173987/epidemiological-clinical-microbiological-and-therapeutic-differences-in-tuberculosis-disease-in-patients-with-and-without-hiv-infection
#11
Javier Martínez-Sanz, María Rosa Lago-Gómez, María Elena Rodríguez-Zurita, Esteban Martín-Echevarría, Miguel Torralba
BACKGROUND AND OBJECTIVE: Our objective is to analyze the incidence of tuberculosis (TB) in our population and to compare the characteristics of patients with and without HIV infection. PATIENTS AND METHODS: Clinical-epidemiological retrospective cohort study that included patients diagnosed with TB with and without HIV infection between 2005-2016 in the province of Guadalajara (Spain). Epidemiological, clinical, microbiological and therapeutic variables were assessed, including microbiological resistances...
April 23, 2018: Medicina Clínica
https://www.readbyqxmd.com/read/29167779/bibliometric-analysis-on-the-risks-of-oral-cancer-for-people-living-with-hiv-aids
#12
Luana Kelle Batista Moura, Mitra Mobin, Francisca Tereza Coelho Matos, Thiago Lima Monte, Eliana Campelo Lago, Carlos Alberto Monteiro Falcão, Maria Ângela de Arêa Leão Ferraz, Tanit Clementino Santos, Fabrício Ibiapina Tapety, Carla Maria de Carvalho Leite Leal Nunes, Laelson Rochelle Milanês Sousa
No abstract text is available yet for this article.
November 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/29147593/rapidly-progressive-disseminated-sporotrichosis-as-the-first-presentation-of-hiv-infection-in-a-patient-with-a-very-low-cd4-cell-count
#13
Isis Cristine Morávia Ribeiro de Oliveira-Esteves, Guilherme Almeida Rosa da Silva, Walter de Araujo Eyer-Silva, Rodrigo Panno Basílio-de-Oliveira, Luciana Ferreira de Araujo, Carlos José Martins, Rogério Neves-Motta, Marcelo Costa Velho Mendes de Azevedo, Dario José Hart Pontes Signorini, Jorge Francisco da Cunha Pinto, Lívia Machado Moura, Rafael Jacyntho Laterça, Diogo Raphael Garcia de Oliveira Pereira, Isabela Vieira do Lago, Fernando Raphael de Almeida Ferry
Sporotrichosis is a human and animal disease caused by species of the Sporothrix schenckii complex. It is classically acquired through traumatic inoculation of fungal elements. Most frequently, sporotrichosis presents as a fixed cutaneous or as a lymphocutaneous form. A much smaller number of cases occur as cutaneous disseminated and disseminated forms. These cases require immediate diagnosis and management to reduce morbidity and mortality. We present the case of a 34-year-old male patient in whom the first presentation of HIV infection was a rapidly progressive sporotrichosis with multiple cutaneous lesions, a high fungal burden in tissues, and pulmonary involvement...
2017: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/29062324/effect-of-vitamin-a-and-vitamin-c-supplementation-on-oxidative-stress-in-hiv-and-hiv-tb-co-infection-at-lagos-university-teaching-hospital-luth-nigeria
#14
RANDOMIZED CONTROLLED TRIAL
Oluwamayowa Makinde, Kunle Rotimi, Victor Ikumawoyi, Titilope Adeyemo, Sunday Olayemi
BACKGROUND: HIV and TB infections are both associated with elevated oxidative stress parameters. Anti-oxidant supplementation may offer beneficial effects in positively modulating oxidative stress parameters in HIV and HIV-TB infected patients. We investigated the effects of vitamin A and C supplementation on oxidative stress in HIV infected and HIV-TB co-infected subjects. METHODS: 40 HIV/TB co-infected and 50 HIV mono-infected patients were divided into 2 equal groups...
June 2017: African Health Sciences
https://www.readbyqxmd.com/read/29045748/conserved-asymmetry-underpins-homodimerization-of-dicer-associated-double-stranded-rna-binding-proteins
#15
Alex Heyam, Claire E Coupland, Clément Dégut, Ruth A Haley, Nicola J Baxter, Leonhard Jakob, Pedro M Aguiar, Gunter Meister, Michael P Williamson, Dimitris Lagos, Michael J Plevin
Double-stranded RNA-binding domains (dsRBDs) are commonly found in modular proteins that interact with RNA. Two varieties of dsRBD exist: canonical Type A dsRBDs interact with dsRNA, while non-canonical Type B dsRBDs lack RNA-binding residues and instead interact with other proteins. In higher eukaryotes, the microRNA biogenesis enzyme Dicer forms a 1:1 association with a dsRNA-binding protein (dsRBP). Human Dicer associates with HIV TAR RNA-binding protein (TRBP) or protein activator of PKR (PACT), while Drosophila Dicer-1 associates with Loquacious (Loqs)...
December 1, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28966749/issues-surrounding-hiv-status-disclosure-experiences-of-seropositive-women-in-lagos-nigeria
#16
Oluwaseun E Oseni, Ifeoma P Okafor, Adekemi O Sekoni
BACKGROUND: Disclosure of human immunodeficiency virus (HIV) seropositivity by infected women is crucial in HIV control. To determine the rates, patterns, effects, and determinants of disclosure of status among HIV-positive women in Lagos, Nigeria. METHODS: This was a descriptive cross-sectional study. Simple random sampling method was used to select 364 HIV-positive women accessing care in HIV treatment centers in Lagos Island. Data were collected using interviewer-administered questionnaires and analyzed with Epi Info (version 3...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28926403/pathways-from-sexual-stigma-to-incident-hiv-and-sexually-transmitted-infections-among-nigerian-msm
#17
Cristina Rodriguez-Hart, Rebecca G Nowak, Rashelle Musci, Danielle German, Ifeanyi Orazulike, Blessing Kayode, Hongjie Liu, Oye Gureje, Trevor A Crowell, Stefan Baral, Man Charurat
OBJECTIVES: Sexual stigma affecting MSM in Nigeria may be an important driver of HIV and other sexually transmitted infections (STIs), but potential mechanisms through which this occurs are not well understood. This study assessed the contributions of suicidal ideation and sexual risk behaviors to causal pathways between stigma and HIV/STIs. DESIGN: Data were collected from the TRUST/RV368 Study, a prospective cohort of 1480 MSM from Abuja and Lagos, Nigeria. METHODS: Participants enrolled from March 2013 to February 2016 were classified into three stigma subgroups based on a latent class analysis of nine stigma indicators...
November 13, 2017: AIDS
https://www.readbyqxmd.com/read/28915113/causative-factors-for-sexual-and-reproductive-health-status-of-pregnant-adolescent-girls-in-urban-communities-of-lagos-nigeria
#18
Yetunde A Kuyinu, Toriola T Femi-Adebayo, Babatunde A Odugbemi, Elochukwu E Ukatu
Background The overall goal of this study was to determine the causative factors for pregnancy status in adolescent girls in two communities in the Lagos Island local government area. Methods A mixed methods (quantitative and qualitative) study reviewing routine health facility antenatal care (ANC) records and conducting focus group discussions among 46 pregnant adolescents, exploring their views about sex, contraception, pregnancy and sexual and reproductive health (SRH) services, was carried out. Key informant interviews were also carried out among healthcare workers and community members to assess their perceptions of adolescents' SRH problems...
September 15, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28885693/epidemiological-and-molecular-analysis-of-hepatitis-b-virus-infection-in-manicurists-in-central-brazil
#19
Larissa Cavaretto, Ana R C Motta-Castro, Sheila A Teles, Fernanda Q Souza, Wesley M Cardoso, Grazielli R de Rezende, Tayana S O Tanaka, Larissa M Bandeira, Gabriela A Cesar, Marco A M Puga, Bruna B Nepomuceno, Bárbara V Lago, Sonia M Fernandes-Fitts
The aim of this study was to investigate the serological and molecular prevalence of hepatitis B virus (HBV) infection in 514 manicurists/pedicurists and identify the risk factors related with this infection. Samples were tested for HBV serological markers, hepatitis C virus (HCV), and human immunodeficiency virus (HIV) by enzyme-linked immunosorbent assay (ELISA). Anti-HBc-positive samples were tested to investigate occult hepatitis B by PCR. HBsAg-positive samples were genotyped and the viral loads of HBV-DNA positive samples were quantified...
February 2018: Journal of Medical Virology
https://www.readbyqxmd.com/read/28826456/chronic-pulmonary-aspergillosis-as-a-cause-of-smear-negative-tb-and-or-tb-treatment-failure-in-nigerians
#20
MULTICENTER STUDY
R O Oladele, N K Irurhe, P Foden, A S Akanmu, T Gbaja-Biamila, A Nwosu, H A Ekundayo, F T Ogunsola, M D Richardson, D W Denning
OBJECTIVE: To evaluate chronic pulmonary aspergillosis (CPA) as an alternative diagnosis of smear-negative tuberculosis (TB) and treatment failure in TB patients in Nigeria. METHODS: We conducted a cross-sectional multicentre survey in human immunodeficiency virus (HIV) positive and negative adult patients at the end of their TB treatment in clinics in Lagos and Ilorin states. All were assessed using clinical examination, chest X-ray (CXR) and aspergillus immunoglobulin G (IgG) serology, and some for sputum fungal culture...
September 1, 2017: International Journal of Tuberculosis and Lung Disease
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