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https://www.readbyqxmd.com/read/27847006/determinants-of-health-system-delay-at-public-and-private-directly-observed-treatment-short-course-facilities-in-lagos-state-nigeria-a-cross-sectional-study
#1
Olusola Adedeji Adejumo, Olusoji James Daniel, Andrew Folarin Otesanya, Esther Ngozi Adejumo
OBJECTIVE/BACKGROUND: Despite several studies on health system delay (HSD) among tuberculosis (TB) patients in Nigeria, no study has compared HSD in private and public health facilities. This study assessed the determinants of HSD in public and private health facilities offering the directly observed treatment, short course (DOTS). METHODS: A descriptive cross-sectional study was conducted. A total of 470 new smear-positive TB patients aged 14years and older were consecutively recruited between October 1, 2012, and December 31, 2012, from 34 (23 public and 11 private) DOTS facilities that offered treatment and microscopy services...
September 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/27836020/high-levels-of-pre-treatment-hiv-drug-resistance-and-treatment-failure-in-nigerian-children
#2
Ragna S Boerma, T Sonia Boender, Kim C E Sigaloff, Tobias F Rinke de Wit, Michael Boele van Hensbroek, Nicaise Ndembi, Titilope Adeyemo, Edamisan O Temiye, Akin Osibogun, Pascale Ondoa, Job C Calis, Alani Sulaimon Akanmu
INTRODUCTION: Pre-treatment HIV drug resistance (PDR) is an increasing problem in sub-Saharan Africa. Children are an especially vulnerable population to develop PDR given that paediatric second-line treatment options are limited. Although monitoring of PDR is important, data on the paediatric prevalence in sub-Saharan Africa and its consequences for treatment outcomes are scarce. We designed a prospective paediatric cohort study to document the prevalence of PDR and its effect on subsequent treatment failure in Nigeria, the country with the second highest number of HIV-infected children in the world...
2016: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/27812146/differences-in-the-access-to-sterilization-between-women-living-and-not-living-with-hiv-results-from-the-genih-study-brazil
#3
Regina Maria Barbosa, Cristiane da Silva Cabral, Tania di Giacomo do Lago, Adriana de Araujo Pinho
BACKGROUND: In many countries, young women of reproductive age have been especially affected by the HIV epidemic, which have fostered research to better understand how HIV infection influences and shapes women´s fertility and reproductive and sexual decisions. In Brazil, few studies have focused on the impact of the HIV epidemic on contraceptive choices among women living with HIV (WLHIV). OBJECTIVE: This study evaluates the impact HIV infection may have in the access to female sterilization in Brazil, using a time-to-event analysis...
2016: PloS One
https://www.readbyqxmd.com/read/27578403/role-of-healthcare-in-childbearing-decision-making-of-wlha-in-nigeria-application-of-pen-3-cultural-model
#4
Y A Sofolahan-Oladeinde, J I Iwelunmor, D F Conserve, A Gbadegesin, C O Airhihenbuwa
Healthcare experiences among women living with HIV/AIDS (WLHA), determine their utilisation of sexual and reproductive health services, which ultimately influences their decisions on childbearing. This study aimed to understand the importance of healthcare support in the childbearing decision-making processes of WLHA, and its impact on eliminating new paediatric HIV infections. We conducted in-depth interviews between July and August 2012 with 15 WLHA receiving clinical HIV care at a teaching hospital in Lagos...
August 31, 2016: Global Public Health
https://www.readbyqxmd.com/read/27578293/cd4-decay-rate-as-an-indicator-of-the-time-interval-between-initial-infection-and-first-diagnosis-among-drug-na%C3%A3-ve-human-immunodeficiency-virus-seropositive-individuals-in-lagos-nigeria
#5
Babatunde Olanrewaju Motayo, Samson O Aturaka, Babatunde A Olusola, I Joseph Ogiogwa, Nataniel N Shidali, Olusola Akingbade, Adedayo O Faneye
OBJECTIVE: The aim of this study was to determine the time interval between human immunodeficiency virus (HIV) infection and the first diagnosis among drug-naïve individuals in Badagry, Nigeria. SUBJECTS AND METHODS: A sample of 213 subjects who tested HIV positive for the first time were enrolled in this study. The HIV diagnosis was performed using Startpak® and Determine® kits, and a CD4 count was carried out using a FACS Count® flow cytometer. The mean CD4 values were determined by gender and age groups...
2016: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/27512845/significant-contribution-of-subtype-g-to-hiv-1-genetic-complexity-in-nigeria-identified-by-a-newly-developed-subtyping-assay-specific-for-subtype-g-and-crf02_ag
#6
Richard A Heipertz, Ojor Ayemoba, Eric Sanders-Buell, Kultida Poltavee, Phuc Pham, Gustavo H Kijak, Esther Lei, Meera Bose, Shana Howell, Anne Marie OʼSullivan, Adam Bates, Taylor Cervenka, Janelle Kuroiwa, Akindiran Akintunde, Onyekachukwu Ibezim, Abraham Alabi, Obumneke Okoye, Mark Manak, Jennifer Malia, Sheila Peel, Mohammed Maisaka, Darrell Singer, Robert J O'Connell, Merlin L Robb, Jerome H Kim, Nelson L Michael, Ogbonnaya Njoku, Sodsai Tovanabutra
While abundant sequence information is available from human immunodeficiency virus type 1 (HIV-1) subtypes A, B, C and CRF01_AE for HIV-1 vaccine design, sequences from West Africa are less represented. We sought to augment our understanding of HIV-1 variants circulating in 6 Nigerian cities as a step to subsequent HIV-1 vaccine development.The G/CRF02_AG multi-region hybridization assay (MHA) was developed to differentiate subtype G, CRF02_AG and their recombinants from other subtypes based on 7 HIV-1 segments...
August 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27423745/trends-and-risk-factors-for-obesity-among-hiv-positive-nigerians-on-antiretroviral-therapy
#7
L O Ezechi, Z A Musa, V O Otobo, I E Idigbe, O C Ezechi
INTRODUCTION: The increased access to antiretroviral therapy has changed the once deadly infection to a chronic medical condition, resulting in a dramatic change in causes of morbidity and mortality among HIV infected individuals. Obesity and its cardiovascular sequelae are increasingly reported in the literature. However, data on the burden, trends and risk factors for obesity are sparse in countries worst hit by the epidemic. OBJECTIVES: To investigate the trend and risk factors for obesity among a cohort of HIV infected adults on antiretroviral therapy...
June 2016: Ceylon Medical Journal
https://www.readbyqxmd.com/read/27347295/risk-factors-and-assessment-for-cardiovascular-disease-among-hiv-positive-patients-attending-a-nigerian-tertiary-hospital
#8
Ifeyinwa Dorothy Osegbe, Oyetunji Olukayode Soriyan, Abiola Ann Ogbenna, Henry Chima Okpara, Elaine Chinyere Azinge
INTRODUCTION: Cardiovascular risk factors are prevalent in HIV-positive patients which places them at increased risk for cardiovascular disease (CVD). We aimed to determine the risk factors and risk assessment for CVD in HIV-positive patients with and without antiretroviral therapy. METHODS: This was a cross-sectional study of HIV-positive patients attending the Lagos University Teaching Hospital, Nigeria. Anthropometric and blood pressure measurements were performed; fasting lipid profile, plasma glucose, homocysteine and hsCRP were determined, as well as prevalences and risk assessments...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27295832/prevalence-of-wasting-stunting-and-underweight-among-hiv-infected-underfives-in-lagos-using-w-h-o-z-score
#9
Patricia E Akintan, Adebola Akinsulie, Edamisan Temiye, Christopher Esezobor
BACKGROUND: HIV affects more than 2.3 million children worldwide and 90% live in Africa. Malnutrition is also a major problem in Africa with 25% of children under the age of five being malnourished. OBJECTIVE: The study is to determine the nutritional status of HIV infected children using weight-for-age, height-for-age and weight-for-height. METHODS: This was a cross sectional descriptive study where the severity of malnutrition based on weight for age, height for age and weight for weight for height of HIV infected children were compared with controls...
April 2015: Nigerian Quarterly Journal of Hospital Medicine
https://www.readbyqxmd.com/read/27295815/selenium-status-and-infant-birth-weight-among-hiv-positive-and-hiv-negative-pregnant-women-in-lagos-nigeria
#10
Christian Chigozie Makwe, Francis Izuegbunam Nwabua, Rose Ihuoma Anorlu
BACKGROUND: During pregnancy, selenium deficiency and reduced antioxidant activities may result in adverse perinatal outcome such as low birthweight, which is associated with significant perinatal morbidity and mortality. Many studies have reported conflicting findings on the relationship between maternal selenium status and infant birth weight. OBJECTIVE: This study is to determine the relationship between maternal serum selenium concentration and infant birthweight in HIV-positive and HIV-negative pregnant women at term...
July 2015: Nigerian Quarterly Journal of Hospital Medicine
https://www.readbyqxmd.com/read/27295814/use-of-hiv-screening-services-and-sexual-behavior-of-in-school-adolescents-in-surulere-lga-lagos-state
#11
A O Sekoni, E O Somefun, O O Fatoba, A T Onajole
BACKGROUND: The health and development.of populations irrespective of where they live is dependent on their behaviour. Adolescents constitute a huge chunk of the global population. A high proportion of the burden of diseases therefore occur in this age group as well. The maturation process occurs throughout this period and behaviours adopted often last for life and are determinants of healthy adult life. High prevalence of Sexually Transmitted Infections including Human Immunodeficiency Virus has been documented in adolescents...
July 2015: Nigerian Quarterly Journal of Hospital Medicine
https://www.readbyqxmd.com/read/27295809/prevalence-of-skin-diseases-in-children-with-human-immunodeficiency-syndrome-infection-in-paediatric-hiv-clinic-of-a-tertiary-hospital-in-nigeria
#12
B O Osinaike, E O Temiye, O Odusote, A O Akinsulie, E Iroha
BACKGROUND: HIV infection/AIDS being a multi-systemic disease affects the skin at various stages in course of the illness. A knowledge of the common skin diseases associated with HIV infection can lead to early detection, appropriate staging and commencement of appropriate care in the infected patients. OBJECTIVE: The study was to document the prevalence and pattern of skin diseases in children with HIV infection seen at the Paediatric department of a tertiary centre in Nigeria...
July 2015: Nigerian Quarterly Journal of Hospital Medicine
https://www.readbyqxmd.com/read/27276764/condom-use-among-antiretroviral-therapy-naive-people-living-with-hiv-at-a-tertiary-health-care-hospital-in-lagos-nigeria-implication-for-prevention-of-new-infections
#13
T M Balogun, B Awofala, I C Iredu, A O Ajayi, M Ohakwere
BACKGROUND: The consistent use of male latex condom significantly reduces the risk of HIV infection among men and women. OBJECTIVE: This study was designed to assess the prevalence and pattern of male and female condom use among antiretroviral therapy naïve people living with HIV (PLHIV) in Lagos, Nigeria. METHODS: This was a cross-sectional descriptive study. Interviewer administered questionnaires were used to collect demographic data of age, gender, marital status, rate, pattern of and reasons for not using condoms among PLHIV...
October 2013: Nigerian Quarterly Journal of Hospital Medicine
https://www.readbyqxmd.com/read/27276759/undergraduate-students-knowledge-and-practice-of-gonorrhea-and-other-sexually-transmitted-infections
#14
A E Joda, F Tayo, B A Aina
BACKGROUND: Sexually transmitted infections (STIs) are a major public health issue. Adolescents and youth (15-24 years) are the age groups at the greater risk for acquiring them. Also a large percentage of new STIs occur in this age group with 7000 young people worldwide acquiring the infection every day. Sexually transmitted infections (STIs) are poorly recognized and inadequately treated in Nigeria despite the fact that they constitute a major risk factor for sexual transmission of HIV infection...
October 2013: Nigerian Quarterly Journal of Hospital Medicine
https://www.readbyqxmd.com/read/27264834/haematological-and-biochemical-response-to-treatment-of-hiv-1-infection-with-a-combination-of-nevirapine-stavudine-lamivudine-in-lagos-nigeria
#15
Nkiru Odunukwe, Oni Idıgbe, Phyllis Kanki, Taiwo Adewole, Daniel Onwujekwe, Rosemary Audu, Joseph Onyewuche
To evaluate the effect of a combination of nevirapine + stavudine + lamivudine on Haematological and Biochemical values of HIV-1 positive patients in Lagos. Fifty patients who met the enrollment criteria for accelerated clinical trial were studied. Ten millimeters of blood was taken from each patient at first visit for basic haematological and biochemical values. Viral load and CD4 cell counts were also analyzed. All the values were repeated at 12 weeks, and 24 weeks, after patients were placed on drug treatment regimen...
September 5, 2005: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/27233248/online-sex-seeking-among-men-who-have-sex-with-men-in-nigeria-implications-for-online-intervention
#16
Shauna Stahlman, Rebecca G Nowak, Hongjie Liu, Trevor A Crowell, Sosthenes Ketende, William A Blattner, Manhattan E Charurat, Stefan D Baral
The TRUST/RV368 project was undertaken to apply innovative strategies to engage Nigerian MSM into HIV care. In this analysis we evaluate characteristics of online sex-seekers from the TRUST/RV368 cohort of 1370 MSM in Abuja and Lagos. Logistic regression and generalized estimating equation models were used to assess associations with online sex-seeking. Online sex-seeking (n = 843, 61.5 %) was associated with participation in MSM community activities, larger social and sexual networks, and higher levels of sexual behavior stigma...
May 27, 2016: AIDS and Behavior
https://www.readbyqxmd.com/read/27186581/cryptococcal-antigenemia-in-nigerian-patients-with-advanced-human-immunodeficiency-virus-influence-of-antiretroviral-therapy-adherence
#17
Rita O Oladele, Alani S Akanmu, Augustina O Nwosu, Folasade T Ogunsola, Malcolm D Richardson, David W Denning
Background.  Cryptococcal meningitis has a high mortality in human immunodeficiency virus (HIV)-infected persons in Africa. This is preventable with early screening and preemptive therapy. We evaluated the prevalence of cryptococcal disease by antigen testing, possible associated factors, and outcomes in HIV-infected patients being managed in a tertiary hospital in Lagos, Nigeria. Methods.  Sera were collected from 214 consenting HIV-infected participants with CD4(+) counts <250 cells/mm(3), irrespective of their antiretroviral therapy (ART) status, between November 2014 and May 2015...
March 2016: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/27093347/provision-of-healthcare-services-to-men-who-have-sex-with-men-in-nigeria-students-attitudes-following-the-passage-of-the-same-sex-marriage-prohibition-law
#18
Adekemi O Sekoni, Kate Jolly, Nicola K Gale, Oluwafemi A Ifaniyi, Esther O Somefun, Emmanuel I Agaba, Victoria A Fakayode
PURPOSE: After signing of the Same-Sex Marriage (Prohibition) Act 2013 in Nigeria, media reports portray widespread societal intolerance toward the lesbian, gay, and bisexual population. This study was conducted to assess the attitudes of university undergraduates in Lagos state, Nigeria, toward provision of healthcare services for men who have sex with men (MSM), because the 2014 same-sex marriage prohibition law stipulates a jail sentence for organizations providing services to MSM...
August 2016: LGBT Health
https://www.readbyqxmd.com/read/27061991/effects-of-aerobic-exercise-on-the-pulmonary-functions-respiratory-symptoms-and-psychological-status-of-people-living-with-hiv
#19
Happiness Anulika Aweto, Ayoola Ibifubara Aiyegbusi, Adaora Justina Ugonabo, Titilope Adenike Adeyemo
BACKGROUND: Pulmonary complications, respiratory symptoms and depression are common occurrences which contribute to the morbidity and mortality seen in individuals living with HIV/AIDS. This study investigated the effect of aerobic exercise on the pulmonary functions, respiratory symptoms and psychological status of people living with HIV. METHODS: This study was conducted in Lagos, Nigeria from October 2014 to May 2015. Forty eligible individuals with HIV aged 18 yr and above participated, of which 33 cooperated to the end...
2016: Journal of Research in Health Sciences
https://www.readbyqxmd.com/read/27061406/overt-and-occult-hepatitis-b-virus-infection-among-treatment-na%C3%A3-ve-hiv-infected-patients-in-brazil
#20
Marina Pedroso Oliveira, Pollyanne Sousa Lemes, Márcia Alves Dias Matos, Nativa Helena Alves Del-Rios, Megmar Aparecida Santos Carneiro, Ágabo Macedo Costa Silva, Carmen Luci Rodrigues Lopes, Sheila Araújo Teles, Rodrigo Sebba Aires, Bárbara Vieira Lago, Natalia Motta Araujo, Regina Maria Bringel Martins
Although hepatitis B virus (HBV) and human immunodeficiency virus (HIV) co-infection is common, only few data are available on HBV among HIV patients including occult hepatitis B infection (OBI), regardless of serological markers. This study aims to determine the prevalence of OBI and overall HBV infection, associated factors, HBV genotypes, and surface (S) gene mutations in a population of treatment-naïve HIV-infected patients in Brazil. A cross-sectional study was conducted in treatment-naïve HIV-infected patients in Central Brazil...
July 2016: Journal of Medical Virology
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