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https://www.readbyqxmd.com/read/28074312/barriers-to-and-facilitators-of-adherence-to-exclusive-breastfeeding-practices-among-hiv-infected-and-non-infected-women-in-jos-nigeria
#1
Bronwynè Coetzee, Mark Tomlinson, Sophia Osawe, Alash'le Amibiku, Ashraf Kagee
Objectives In Nigeria adherence to exclusive breastfeeding (EBF) practices is currently suboptimal and a better understanding of the factors affecting adherence to EBF is needed. We sought to identify and delineate the barriers to and facilitators of adherence to EBF amongst HIV-infected and uninfected women in Nigeria. Methods We explored the barriers and facilitators to EBF amongst 37 (25 HIV-infected and 12 HIV-uninfected) pregnant women attending an antenatal clinic in Jos, Nigeria. In-depth interviews were conducted with each of the pregnant women in their third trimester of pregnancy and again 1 month after giving birth...
January 10, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28063260/prevalence-of-communication-between-mothers-and-daughters-on-sexuality-and-associated-factors-in-sagamu-southwest-nigeria
#2
Oluwadamilola A Opawale, Victor J Animasahun, Helena J Chapman
BACKGROUND: As adolescents transition from childhood to adulthood, effective mother-daughter communication on sexuality plays a role in reducing high-risk behaviours linked to human immunodeficiency virus (HIV) infection and early pregnancy and childbirth. The objective of the study was to examine the prevalence of mother-daughter communication on sexuality and associated factors in Sagamu, southwest Nigeria. METHODS: Using multistage sampling, surveys were conducted using 234 female youth enrolled at a secondary school...
January 7, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28053917/mortality-among-pulmonary-tuberculosis-and-hiv-1-co-infected-nigerian-children-being-treated-for-pulmonary-tuberculosis-and-on-antiretroviral-therapy-a-retrospective-cohort-study
#3
Augustine O Ebonyi, Stephen Oguche, Oche O Agbaji, Atiene S Sagay, Prosper I Okonkwo, John A Idoko, Phyllis J Kanki
BACKGROUND: Mortality data, including the risk factors for mortality in HIV-infected children with pulmonary TB (PTB) being treated for PTB and who are on antiretroviral therapy (ART), are scarce in Nigeria. We determined the mortality rate and risk factors for mortality among such children, at the pediatric HIV clinic of the Jos University Teaching Hospital (JUTH) in Jos, Nigeria. METHODS: We performed a retrospective cohort study on 260 PTB-HIV-1 co-infected children, aged 2 months to 13 years, being treated for PTB and on ART from July 2005 to March 2013...
December 2016: Germs
https://www.readbyqxmd.com/read/28046045/playing-the-catch-up-game-accelerating-the-scale-up-of-prevention-of-mother-to-child-transmission-of-hiv-pmtct-services-to-eliminate-new-pediatric-hiv-infection-in-nigeria
#4
Edward Adekola Oladele, Hadiza Khamofu, Seun Asala, Mariya Saleh, Uche Ralph-Opara, Charles Nwosisi, Chukwuma Anyaike, Catherine Gana, Oluwasanmi Adedokun, Rebecca Dirks, Olufunsho Adebayo, Modupe Oduwole, Justin Mandala, Kwasi Torpey
INTRODUCTION: As the world is making progress towards elimination of mother-to-child transmission of HIV, poor coverage of PMTCT services in Nigeria remains a major challenge. In order to address this, scale-up was planned with activities organized into 3 phases. This paper describes the process undertaken in eight high burden Nigerian states to rapidly close PMTCT coverage gaps at facility and population levels between February 2013 and March 2014. METHODS: Activities were grouped into three phases-pre-assessment phase (engagement of a wide range of stakeholders), assessment (rapid health facility assessment, a cross sectional survey using mixed methods conducted in the various states between Feb and May 2013 and impact modelling), and post-assessment (drawing up costed state operational plans to achieve eMTCT by 2015, data-driven smart scale-up)...
2017: PloS One
https://www.readbyqxmd.com/read/27973285/medication-adherence-and-risk-factors-for-nonadherence-among-hiv-positive-pregnant-women-taking-tenofovir-based-fixed-dose-combination-regimen-in-nigeria
#5
O Omonaiye, K A Agu
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27958243/prevalence-and-predictors-of-placental-malaria-in-human-immunodeficiency-virus-positive-women-in-nigeria
#6
E O Izuka, E O Ugwu, S N Obi, B C Ozumba, T U Nwagha, C E Obiora-Izuka
BACKGROUND: Human immunodeficiency virus (HIV)-infected pregnant women have alterations in cellular and humoral immunity that increase the risks to placental malaria infection. AIM: This study aimed at determining the prevalence and predictors of placental malaria among HIV-positive women in Nigeria. MATERIALS AND METHODS: It was a longitudinal cohort study of pregnant women receiving antenatal care at a tertiary hospital in Nigeria. Peripheral blood sample for packed cell volume estimation and placental blood sample for malaria parasite estimation were collected from each participant at a presentation in labor and upon delivery, respectively...
January 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/27956749/non-adoption-of-option-b-for-prevention-of-mother-to-child-transmission-of-hiv-in-nigeria-a-look-at-the-policymaking-process
#7
Babayemi Oluwaseun Olakunde, Chinwendu Daniel Ndukwe
In 2012, the World Health Organization recommended 'Option B+' (lifelong antiretroviral treatment for HIV-infected pregnant women regardless of their CD4 count or WHO clinical stage) for prevention of mother-to-child transmission of HIV-based on its operational and clinical advantages. By 2015, 21 out of the 22 Global Plan priority countries had adopted the Option B+ approach. Despite its huge HIV burden, Nigeria is the only country yet to adopt Option B+. We analyse the policymaking process on Option B+ in Nigeria from 2012-2015, highlighting how factors related to the content (uncertainty about Option B+, lack of local evidence), actors (interest and power) and context (low domestic funding and poor retention in care) affected the policymaking process and present the implications of this decision for improving HIV response in Nigeria...
December 12, 2016: Journal of Public Health Policy
https://www.readbyqxmd.com/read/27940480/sex-disparities-in-outcomes-among-adults-on-long-term-antiretroviral-treatment-in-northern-nigeria
#8
Baba M Musa, Musa A Garbati, Ibrahim M Nashabaru, Shehu M Yusuf, Aisha M Nalado, Daiyabu A Ibrahim, Melynda N Simmons, Muktar H Aliyu
BACKGROUND: There are conflicting reports of sex differences in HIV treatment outcomes in Africa. We investigated sex disparities in treatment outcomes for adults on first line antiretroviral treatment (ART) in Nigeria. METHODS: We compared clinical and immunologic responses to ART between HIV-infected men (n=205) and women (n=140) enrolled in an ART program between June 2004 and December 2007, with follow-up through June 2014. We employed Kaplan-Meier estimates to examine differences in time to immunologic failure and loss to follow-up (LTFU), and generalized estimating equations to assess changes in CD4+ count by sex...
January 2017: International Health
https://www.readbyqxmd.com/read/27936236/an-evaluation-of-selected-populations-for-hiv-1-vaccine-cohort-development-in-nigeria
#9
Ogbonnaya S Njoku, Mark M Manak, Robert J O'Connell, Ashley L W Shutt, Jennifer A Malia, Richard A Heipertz, Sodsai Tovanabutra, Mark J Milazzo, Gideon Akindiran Akintunde, Abraham S Alabi, Aminu Suleiman, Amos A Ogundeji, Terfa S Kene, Robbie Nelson, Ojor R Ayemoba, Darrell E Singer, Merlin L Robb, Sheila A Peel, Nelson L Michael
Development of a globally effective HIV-1 vaccine will need to encompass Nigeria, one of the hardest hit areas, with an estimated 3.2 million people living with HIV. This cross-sectional Institutional Review Board (IRB) approved study was conducted in 2009-12 at four market sites and two highway settlements sites in Nigeria to identify and characterize populations at high risk for HIV; engage support of local stakeholders; and assess the level of interest in future vaccine studies. Demographic, HIV risk data were collected by structured interviewer-administered questionnaires...
2016: PloS One
https://www.readbyqxmd.com/read/27933462/what-do-you-need-to-get-male-partners-of-pregnant-women-tested-for-hiv-in-resource-limited-settings-the-baby-shower-cluster-randomized-trial
#10
Echezona E Ezeanolue, Michael C Obiefune, Wei Yang, Chinenye O Ezeanolue, Jennifer Pharr, Alice Osuji, Amaka G Ogidi, Aaron T Hunt, Dina Patel, Gbenga Ogedegbe, John E Ehiri
Male partner involvement has the potential to increase uptake of interventions to prevent mother-to-child transmission of HIV (PMTCT). Finding cultural appropriate strategies to promote male partner involvement in PMTCT programs remains an abiding public health challenge. We assessed whether a congregation-based intervention, the Healthy Beginning Initiative (HBI), would lead to increased uptake of HIV testing among male partners of pregnant women during pregnancy. A cluster-randomized controlled trial of forty churches in Southeastern Nigeria randomly assigned to either the HBI (intervention group; IG) or standard of care referral to a health facility (control group; CG) was conducted...
December 8, 2016: AIDS and Behavior
https://www.readbyqxmd.com/read/27931519/high-prevalence-of-hiv-chlamydia-and-gonorrhoea-among-men-who-have-sex-with-men-and-transgender-women-attending-trusted-community-centres-in-abuja-and-lagos-nigeria
#11
Babajide Keshinro, Trevor A Crowell, Rebecca G Nowak, Sylvia Adebajo, Sheila Peel, Charlotte A Gaydos, Cristina Rodriguez-Hart, Stefan D Baral, Melissa J Walsh, Ogbonnaya S Njoku, Sunday Odeyemi, Teclaire Ngo-Ndomb, William A Blattner, Merlin L Robb, Manhattan E Charurat, Julie Ake
INTRODUCTION: Sexually transmitted infection (STI) and HIV prevalence have been reported to be higher amongst men who have sex with men (MSM) in Nigeria than in the general population. The objective of this study was to characterize the prevalence of HIV, chlamydia and gonorrhoea in this population using laboratory-based universal testing. METHODS: TRUST/RV368 represents a cohort of MSM and transgender women (TGW) recruited at trusted community centres in Abuja and Lagos, Nigeria, using respondent-driven sampling (RDS)...
2016: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/27917196/five-years-retrospective-cohort-analysis-of-treatment-outcomes-of-tb-hiv-patients-at-a-pepfar-dots-centre-in-south-eastern-nigeria
#12
Omotowo I Babatunde, Ekwueme O Christiandolus, Eke C Bismarck, Obi I Emmanuel, Agunwa C Chike, Eyisi I Gabriel
BACKGROUND: Human immunodeficiency virus (HIV) associated tuberculosis (TB) remains a major global public health challenge, with an estimated 1.4 million patients worldwide. Co-infection with HIV leads to challenges in the diagnosis and treatment of patients. OBJECTIVES: The aim of this study was to assess treatment outcomes of a cohort of smear positive TB-HIV co-infected patients over a five-year study period. METHODS: A retrospective cohort study of 600 smear-positive tuberculosis patients registered at the chest unit of the University of Nigeria Teaching Hospital, Enugu from January 2008 to December 2012 was done...
September 2016: African Health Sciences
https://www.readbyqxmd.com/read/27911921/what-is-the-economic-burden-of-subsidized-hiv-aids-treatment-services-on-patients-in-nigeria-and-is-this-burden-catastrophic-to-households
#13
Enyi Etiaba, Obinna Onwujekwe, Kwasi Torpey, Benjamin Uzochukwu, Robert Chiegil
BACKGROUND: A gap in knowledge exists regarding the economic burden on households of subsidized anti-retroviral treatment (ART) programs in Nigeria. This is because patients also incur non-ART drug costs, which may constrain the delivery and utilisation of subsidized services. METHODS: An exit survey of adults (18+years) attending health facilities for HIV/AIDS treatment was conducted in three states in Nigeria (Adamawa, Akwa Ibom and Anambra). In the states, ART was fully subsidized but there were different payment modalities for other costs of treatment...
2016: PloS One
https://www.readbyqxmd.com/read/27847006/determinants-of-health-system-delay-at-public-and-private-directly-observed-treatment-short-course-facilities-in-lagos-state-nigeria-a-cross-sectional-study
#14
Olusola Adedeji Adejumo, Olusoji James Daniel, Andrew Folarin Otesanya, Esther Ngozi Adejumo
OBJECTIVE/BACKGROUND: Despite several studies on health system delay (HSD) among tuberculosis (TB) patients in Nigeria, no study has compared HSD in private and public health facilities. This study assessed the determinants of HSD in public and private health facilities offering the directly observed treatment, short course (DOTS). METHODS: A descriptive cross-sectional study was conducted. A total of 470 new smear-positive TB patients aged 14years and older were consecutively recruited between October 1, 2012, and December 31, 2012, from 34 (23 public and 11 private) DOTS facilities that offered treatment and microscopy services...
September 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/27844297/a-decade-of-monitoring-hiv-epidemics-in-nigeria-positioning-for-post-2015-agenda
#15
Oluyemisi Akinwande, Adebobola Bashorun, Aderemi Azeez, Francis Agbo, Patrick Dakum, Alashle Abimiku, Camara Bilali, John Idoko, Kayode Ogungbemi
BACKGROUND: Nigeria accounts for 9% of the global HIV burden and is a signatory to Millennium Development Goals as well as the post-2015 Sustainable Development Goals. This paper reviews maturation of her HIV M&E system and preparedness for monitoring of the post-2015 agenda. METHODS: Using the UNAIDS criteria for assessing a functional M&E system, a mixed-methods approach of desk review and expert consultations, was employed. RESULTS: Following adoption of a multi-sectoral M&E system, Nigeria experienced improved HIV coordination at the National and State levels, capacity building for epidemic appraisals, spectrum estimation and routine data quality assessments...
November 14, 2016: AIDS and Behavior
https://www.readbyqxmd.com/read/27836020/high-levels-of-pre-treatment-hiv-drug-resistance-and-treatment-failure-in-nigerian-children
#16
Ragna S Boerma, T Sonia Boender, Kim C E Sigaloff, Tobias F Rinke de Wit, Michael Boele van Hensbroek, Nicaise Ndembi, Titilope Adeyemo, Edamisan O Temiye, Akin Osibogun, Pascale Ondoa, Job C Calis, Alani Sulaimon Akanmu
INTRODUCTION: Pre-treatment HIV drug resistance (PDR) is an increasing problem in sub-Saharan Africa. Children are an especially vulnerable population to develop PDR given that paediatric second-line treatment options are limited. Although monitoring of PDR is important, data on the paediatric prevalence in sub-Saharan Africa and its consequences for treatment outcomes are scarce. We designed a prospective paediatric cohort study to document the prevalence of PDR and its effect on subsequent treatment failure in Nigeria, the country with the second highest number of HIV-infected children in the world...
2016: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/27829033/outcomes-of-nigeria-s-hiv-aids-treatment-program-for-patients-initiated-on-antiretroviral-treatment-between-2004-2012
#17
Ibrahim Dalhatu, Dennis Onotu, Solomon Odafe, Oseni Abiri, Henry Debem, Simon Agolory, Ray W Shiraishi, Andrew F Auld, Mahesh Swaminathan, Kainne Dokubo, Evelyn Ngige, Chukwuemeka Asadu, Emmanuel Abatta, Tedd V Ellerbrock
BACKGROUND: The Nigerian Antiretroviral therapy (ART) program started in 2004 and now ranks among the largest in Africa. However, nationally representative data on outcomes have not been reported. METHODS: We evaluated retrospective cohort data from a nationally representative sample of adults aged ≥15 years who initiated ART during 2004 to 2012. Data were abstracted from 3,496 patient records at 35 sites selected using probability-proportional-to-size (PPS) sampling...
2016: PloS One
https://www.readbyqxmd.com/read/27822455/burden-of-cancers-attributable-to-infectious-agents-in-nigeria-2012-2014
#18
Michael Odutola, Elima E Jedy-Agba, Eileen O Dareng, Emmanuel Aja Oga, Festus Igbinoba, Theresa Otu, Emmanuel Ezeome, Ramatu Hassan, Clement A Adebamowo
INTRODUCTION: Infections by certain viruses, bacteria, and parasites have been identified as risk factors for some cancers. In Nigeria, like many other developing countries, infections remain a leading cause of morbidity and mortality. While there are data on the incidence of different cancers in Nigeria, there has been no study of cancers attributable to infections. This study was carried out to determine the burden of cancers attributable to infections using data from two population-based cancer registries (PBCRs) in Nigeria...
2016: Frontiers in Oncology
https://www.readbyqxmd.com/read/27800100/acceptance-of-provider-initiated-testing-and-counseling-for-hiv-infection-by-caregivers-in-a-tertiary-health-institution-in-abuja-nigeria-a-cross-sectional-study
#19
Adaora Adeline Okechukwu, Eno Ekop, Chinwendu Daniel Ndukwe, Kudirat Eyinade Olateju
INTRODUCTION: Less than 10% of HIV positive children are enrolled into antiretroviral treatment program in the country. Provider-initiated testing and counseling was introduced to increasing uptake of HIV testing. The aim of this study is to determine the acceptability and factors undermining the acceptance of this laudable initiative by parents/caregivers of children attending paediatric out patient clinical services in our health institution. METHODS: A cross sectional study of children aged 18 months to 18 years and their parents/caregivers attending paediatric outpatient clinic of the hospital was undertaken for the above objectives...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27764094/long-term-outcomes-on-antiretroviral-therapy-in-a-large-scale-up-program-in-nigeria
#20
Seema T Meloni, Charlotte A Chang, Geoffrey Eisen, Toyin Jolayemi, Bolanle Banigbe, Prosper I Okonkwo, Phyllis J Kanki
BACKGROUND: While there has been a rapid global scale-up of antiretroviral therapy programs over the past decade, there are limited data on long-term outcomes from large cohorts in resource-constrained settings. Our objective in this evaluation was to measure multiple outcomes during first-line antiretroviral therapy in a large treatment program in Nigeria. METHODS: We conducted a retrospective multi-site program evaluation of adult patients (age ≥15 years) initiating antiretroviral therapy between June 2004 and February 2012 in Nigeria...
2016: PloS One
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