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https://www.readbyqxmd.com/read/28723963/impact-of-thyroid-function-abnormalities-on-reproductive-hormones-during-menstrual-cycle-in-premenopausal-hiv-infected-females-at-nauth-nnewi-nigeria
#1
Nkiruka Rose Ukibe, Solomon Nwabueze Ukibe, Obiageli Fidelia Emelumadu, Chinedum Charles Onyenekwe, Joseph Eberendu Ahaneku, Anthony Osita Igwegbe, Ifeoma Nwamaka Monago, Amobi Linus Ilika
BACKGROUND: This was a prospective study designed to evaluate the impact of thyroid function abnormalities on reproductive hormones during menstrual cycle in HIV infected females at Nnamdi Azikiwe University Teaching Hospital Nnewi, South-East Nigeria. METHODS: The study randomly recruited 35 Symptomatic HIV infected females and 35 Symptomatic HIV infected females on antiretroviral therapy (HAART) for not less than six weeks from an HIV clinic and 40 apparently heathy control females among the hospital staff of NAUTH Nnewi...
2017: PloS One
https://www.readbyqxmd.com/read/28721101/survey-of-malaria-and-anti-dengue-virus-igg-among-febrile-hiv-infected-patients-attending-a-tertiary-hospital-in-abuja-nigeria
#2
Jelili Olaide Mustapha, Anthony Uchenna Emeribe, Idris Abdullahi Nasir
BACKGROUND: Dengue and malaria are infections, of great public health concern, especially in sub-Saharan Africa where the burden of HIV infection is high. This study was conducted to determine the seroprevalence of dengue virus IgG antibodies and dengue/malaria coinfection among febrile HIV-infected patients attending the University of Abuja Teaching Hospital, Gwagwalada, Abuja. METHODS: In this cross-sectional study, blood samples from 178 consenting HIV-infected patients receiving antiretroviral therapy were collected and tested for plasmodiasis and anti-Dengue virus IgG using malaria microscopy and ELISA, respectively...
2017: HIV/AIDS: Research and Palliative Care
https://www.readbyqxmd.com/read/28705148/correlates-of-facility-delivery-for-rural-hiv-positive-pregnant-women-enrolled-in-the-moment-nigeria-prospective-cohort-study
#3
Nadia A Sam-Agudu, Christopher Isah, Chinenye Fan-Osuala, Salome Erekaha, Habib O Ramadhani, Udochisom Anaba, Olusegun A Adeyemi, Grace Manji-Obadiah, Daniel Lee, Llewellyn J Cornelius, Manhattan Charurat
BACKGROUND: Low rates of maternal healthcare service utilization, including facility delivery, may impede progress in the prevention of mother-to-child transmission of HIV (PMTCT) and in reducing maternal and infant mortality. The MoMent (Mother Mentor) study investigated the impact of structured peer support on early infant diagnosis presentation and postpartum maternal retention in PMTCT care in rural Nigeria. This paper describes baseline characteristics and correlates of facility delivery among MoMent study participants...
July 14, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28699851/dynamics-of-cd4-cell-count-among-hiv-infected-individuals-in-lagos-nigeria
#4
Babatunde O Motayo, Babatunde A Olusola, Adedayo O Faneye, Solomon Aturaka, Olukunle Oluwasemowo, Joseph I Ogiogwa
Human Immunodeficiency virus (HIV) infection leads to progressive loss of CD4 T- cells. Antiretroviral therapy has been able to inhibit this process, resulting in significant level of immune recovery and function. Our aim is to investigate the dynamics of CD4 recovery among HIV patients in Lagos, Nigeria. 213 HIV positive individuals were enrolled between October 2007 and May 2008, and followed up for 9 months based on CD4 count, CD4 analysis was done by flow cytometry at enrolment and after every 3 months...
July 12, 2017: Journal of Immunoassay & Immunochemistry
https://www.readbyqxmd.com/read/28693114/comparison-of-tanner-staging-of-hiv-infected-and-uninfected-girls-at-the-university-of-nigeria-teaching-hospital-ituku-ozalla-enugu-nigeria
#5
Ogochukwu N Iloh, Kenechukwu K Iloh, Agozie C Ubesie, Ifeoma J Emodi, Anthony N Ikefuna, Ngozi S Ibeziako
BACKGROUND: A number of factors influence sexual maturation in adolescents, including chronic illnesses like HIV. Marshall and Tanner devised a method of classifying the adolescent based on the level of sexual maturation into five stages. This study compared the Tanner staging of HIV-infected and uninfected girls. METHODS: This was a cross-sectional study of 100 HIV-infected girls aged 8-18 years and 100 uninfected counterparts matched for age and social class. Using standard photographs as a guide, stages of sexual maturation were determined according to the method proposed by Marshall and Tanner...
June 23, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28690879/epidemiological-characteristics-and-clinical-outcome-of-hiv-related-tuberculosis-in-a-population-of-tb-patients-in-south-western-nigeria
#6
Olugbenga A Olowe, Olufunmilola B Makanjuola, Adeniyi S Adekanmi, Olusola J Adefioye, Rita A Olowe
Tuberculosis (TB) is the second leading cause of death from infectious disease globally with its impact more dramatic in resource limited settings. Individuals with human immunodeficiency virus (HIV) infection who also develop tuberculosis represent a significant challenge to TB control. This study was carried out to determine the prevalence of TB-HIV coinfection and pattern of infection among TB patients. We also compared treatment outcome among coinfected patients with those not coinfected. A six-year retrospective review of records of patients managed at the Tuberculosis Treatment Center of the LAUTECH Teaching Hospital, South-Western Nigeria from January 2009 to December 2014 was carried out...
June 2017: European Journal of Microbiology & Immunology
https://www.readbyqxmd.com/read/28673018/hypertension-in-treated-and-untreated-patients-with-hiv-a-study-from-2011-to-2013-at-the-jos-university-teaching-hospital-nigeria
#7
Samson E Isa, Arthur R Kang'ombe, Gomerep S Simji, Nathan Y Shehu, Agbaji O Oche, John A Idoko, Luis E Cuevas, Geoffrey V Gill
Background: Individuals with HIV, especially those on antiretroviral therapy (ART), may have increased risk of hypertension. We investigated the prevalence of hypertension at enrolment and 12 months after commencing ART in a Nigerian HIV clinic. Methods: Data from patients enrolled for ART from 2011 to 2013 were analysed, including 2310 patients at enrolment and 1524 re-evaluated after 12 months of ART. The presence of hypertension, demographic, clinical and biochemical data were retrieved from standardized databases...
April 1, 2017: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28672738/comparison-of-tanner-staging-of-hiv-infected-and-uninfected-girls-at-the-university-of-nigeria-teaching-hospital-ituku-ozalla-enugu-nigeria
#8
Ogochukwu N Iloh, Kenechukwu K Iloh, Agozie C Ubesie, Ifeoma J Emodi, Anthony N Ikefuna, Ngozi S Ibeziako
BACKGROUND: A number of factors influence sexual maturation in adolescents, including chronic illnesses like HIV. Marshall and Tanner devised a method of classifying the adolescent based on the level of sexual maturation into five stages. This study compared the Tanner staging of HIV-infected and uninfected girls. METHODS: This was a cross-sectional study of 100 HIV-infected girls aged 8-18 years and 100 uninfected counterparts matched for age and social class. Using standard photographs as a guide, stages of sexual maturation were determined according to the method proposed by Marshall and Tanner...
July 26, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28670643/factors-associated-with-tb-hiv-co-infection-among-drug-sensitive-tuberculosis-patients-managed-in-a-secondary-health-facility-in-lagos-nigeria
#9
Olusola A Adejumo, Olusoji J Daniel, Andrew F Otesanya, Adebukola A Adegbola, Temitope Femi-Adebayo, Abimbola Bowale, Sunday Adesola, Olugbenga O Kuku, Kehinde O Otemuyiwa, Shafaatu N Oladega, Eze O Johnson, Ayodeji A Falana, Olusola Dawodu, Henry Owuna, Ganiyat Osoba, Adetokunbo Dacosta
BACKGROUND: This study assessed factors associated with TB/HIV co-infection among TB patients managed in a secondary health facility in Lagos Nigeria. MATERIALS AND METHODS: A retrospective review of treatment cards of patients seen at a secondary referral hospital between January 1 2014 and December 31 2014 was conducted. Treatment outcomes and factors associated with TB/HIV co-infection were assessed. RESULTS: Of the 334 records of patients reviewed, the proportion of patients with TB/HIV co-infection was 21...
2017: African Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28670640/peripheral-parasitaemia-and-its-association-with-plasma-cytokines-levels-in-malaria-infected-pregnant-women-in-aba-abia-state-nigeria
#10
M O Ifeanyichukwu, O C Okamgba, G I Amilo, E A Nwokorie
BACKGROUND: Cytokines in pregnant female may not be a normal phenomenon as malarial infection is often associated with strong CD4+ cell activation and up-regulation of pro-inflammatory cytokines. We investigated the relationship between peripheral parasitaemia and plasma levels of cytokines among malaria infected pregnant women in Aba, Abia State, Nigeria. MATERIALS AND METHODS: A total of 206 non-HIV positive asymptomatic malaria parasitaemic (n=144) and non-parasitaemic (n=62) pregnant women were recruited for this study alongside 80 non-pregnant women who served as positive (n=40) and negative (n=40) controls...
2017: African Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28670638/a-comparison-of-rapid-diagnostic-testing-by-plasmodium-lactate-dehydrogenase-and-quantitative-buffy-coat-technique-in-malaria-diagnosis-in-children
#11
Ifeanyi Kanayo Ifeorah, Biobele J Brown, Olugbemiro O Sodeinde
BACKGROUND: The World Health Organization (WHO) considers early and rapid diagnosis as one of the strategies to control malaria. This study compared the performance of Quantitative Buffy Coat (QBC) test and the Plasmodium lactate dehydrogenase (pLDH) rapid diagnostic test (RDT) with microscopy as the gold standard. MATERIALS AND METHODS: The study involved children ages 0-5 years who presented with a history of fever at the University College Hospital, Ibadan, Nigeria...
2017: African Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28656926/structural-echocardiographic-abnormalities-seen-in-hiv-aids-patients-are-independent-of-cd4-count
#12
J A Ogunmodede, P M Kolo, I A Katibi, A K Salami, Abo Omotoso
INTRODUCTION: The human immunodeficiency virus (HIV) infection remains one of the most daunting public health challenges today. Cardiac involvement in HIV/acquired immune deficiency syndrome (AIDS) is frequent and has been recognized on autopsy since the emergence of the pandemic. The objective of the study was to assess the pattern of structural echocardiographic (echo) findings in HIV/AIDS patients and compare this to the echo findings in apparently healthy HIV-negative controls. MATERIALS AND METHODS: One hundred and fifty HIV-positive patients were recruited consecutively from the HIV patients attending the University of Ilorin Teaching Hospital, Ilorin, North Central, Nigeria...
June 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28652861/erratum-to-outcome-of-hiv-associated-lymphoma-in-a-resource-limited-setting-of-jos-nigeria
#13
Olugbenga Akindele Silas, Chad J Achenbach, Lifang Hou, Robert L Murphy, Julie O Egesie, Solomon A Sagay, Oche O Agbaji, Patricia A Agaba, Jonah Musa, Agabus N Manasseh, Ezra D Jatau, Ayuba M Dauda, Maxwell O Akanbi, Barnabas M Mandong
[This corrects the article DOI: 10.1186/s13027-017-0144-7.].
2017: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/28652217/tuberculosis-and-diabetes-in-nigerian-patients-with-and-without-hiv
#14
Lovett Lawson, Magdalena Muc, Olanrewaju Oladimeji, Chijioke Iweha, Blessing Opoola, Saddiq T Abdurhaman, John S Bimba, Luis E Cuevas
BACKGROUND: Type 2 diabetes mellitus (DM) and HIV increase the risk of tuberculosis (TB). The frequency of DM among patients with TB with and without HIV is poorly documented in many low- and middle-income countries. METHODS: This was a cross-sectional hospital-based study performed in Abuja, Nigeria. Adults with presumptive TB were screened consecutively. Sputum culture was used for TB screening and blood was used for HIV screening, as well as fasting plasma glucose (FPG) and glycated haemoglobin (HbA1c) assessment for the diagnosis of DM...
June 23, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28619407/should-they-also-have-babies-community-attitudes-toward-sexual-and-reproductive-rights-of-people-living-with-hiv-aids-in-nigeria
#15
Zubairu Iliyasu, Hadiza S Galadanci, Yusuf A Ibrahim, Musa Babashani, Mohammed S Mijinyawa, Melynda Simmons, Muktar H Aliyu
BACKGROUND: People living with HIV have the right to healthy, satisfying sex lives and to appropriate services to ensure their sexual and reproductive health, including having healthy children. The reproductive rights of people living with HIV/AIDS are, however, often met with skepticism and discrimination, despite recent advances in HIV treatment. OBJECTIVE: To assess the attitudes of community members in Kano, Nigeria, toward the right of persons living with HIV/AIDS to have healthy sexual relationships and bear children...
March 2017: Annals of Global Health
https://www.readbyqxmd.com/read/28602050/effect-of-hiv-infection-on-outcomes-after-surgical-repair-of-genital-fistula
#16
Steven N Shephard, Sunday J Lengmang, Stephen A Anzaku, Oluwatobi V Mamven, Carolyn V Kirschner
OBJECTIVE: To compare outcomes following surgical repair of genital fistula among Nigerian women with or without HIV. METHODS: A retrospective review was conducted of all genital fistula repair surgeries performed at Evangel Vesicovaginal Fistula Center in Jos, Nigeria, between January 1, 2004, and April 30, 2014. Patient characteristics, HIV status, genital fistula characteristics, and postoperative outcomes were assessed for between-group variance. The odds ratio (OR) and 95% confidence intervals (CIs) were the primary measures used for determining the association between HIV status and surgical outcomes...
June 11, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28592989/outcome-of-hiv-associated-lymphoma-in-a-resource-limited-setting-of-jos-nigeria
#17
Olugbenga Akindele Silas, Chad J Achenbach, Lifang Hou, Robert L Murphy, Julie O Egesie, Solomon A Sagay, Oche O Agbaji, Patricia E Agaba, Jonah Musa, Agabus N Manasseh, Ezra D Jatau, Ayuba M Dauda, Maxwell O Akanbi, Barnabas M Mandong
BACKGROUND: Lymphoma is a leading cause of cancer-related death among human immunodeficiency virus (HIV)-infected individuals in the current era of potent anti-retroviral therapy (ART). Globally, mortality after HIV-associated lymphoma has profound regional variation. Little is known about HIV-associated lymphoma mortality in Nigeria and other resource-limited setting in sub-Saharan Africa. Therefore, we evaluated the all-cause mortality after lymphoma and associated risk factors including HIV at the Jos University Teaching Hospital (JUTH) Nigeria...
2017: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/28577548/depression-suicidality-and-alcohol-use-disorder-among-people-living-with-hiv-aids-in-nigeria
#18
Catherine O Egbe, Patrick S Dakum, Ernest Ekong, Brandon A Kohrt, John G Minto, Cynthia J Ticao
BACKGROUND: People Living with HIV/AIDS (PLHIV) face various day-to-day and long-term personal, interpersonal, social, physical and psychological challenges as a result of, and in addition to the health conditions they are susceptible to due to their HIV status. There is a dearth of large-scale research to provide robust prevalence estimates of mental health problems among PLHIV, especially in Nigeria. This study aimed to ascertain the prevalence and factors associated with major depressive episodes, suicidality, and alcohol use disorder among people living with HIV/AIDS in Nigeria...
June 2, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28570507/trends-in-prevalence-of-advanced-hiv-disease-at-antiretroviral-therapy-enrollment-10-countries-2004-2015
#19
Andrew F Auld, Ray W Shiraishi, Ikwo Oboho, Christine Ross, Moses Bateganya, Valerie Pelletier, Jacob Dee, Kesner Francois, Nirva Duval, Mayer Antoine, Chris Delcher, Gracia Desforges, Mark Griswold, Jean Wysler Domercant, Nadjy Joseph, Varough Deyde, Yrvel Desir, Joelle Deas Van Onacker, Ermane Robin, Helen Chun, Isaac Zulu, Ishani Pathmanathan, E Kainne Dokubo, Spencer Lloyd, Rituparna Pati, Jonathan Kaplan, Elliot Raizes, Thomas Spira, Kiren Mitruka, Aleny Couto, Eduardo Samo Gudo, Francisco Mbofana, Melissa Briggs, Charity Alfredo, Carla Xavier, Alfredo Vergara, Ndapewa Hamunime, Simon Agolory, Gram Mutandi, Naemi N Shoopala, Souleymane Sawadogo, Andrew L Baughman, Adebobola Bashorun, Ibrahim Dalhatu, Mahesh Swaminathan, Dennis Onotu, Solomon Odafe, Oseni Omomo Abiri, Henry H Debem, Hank Tomlinson, Velephi Okello, Peter Preko, Trong Ao, Caroline Ryan, George Bicego, Peter Ehrenkranz, Harrison Kamiru, Harriet Nuwagaba-Biribonwoha, Gideon Kwesigabo, Angela A Ramadhani, Kahemele Ng'wangu, Patrick Swai, Mohamed Mfaume, Ramadhani Gongo, Deborah Carpenter, Timothy D Mastro, Carol Hamilton, Julie Denison, Fred Wabwire-Mangen, Olivier Koole, Kwasi Torpey, Seymour G Williams, Robert Colebunders, Julius N Kalamya, Alice Namale, Michelle R Adler, Bridget Mugisa, Sundeep Gupta, Sharon Tsui, Eric van Praag, Duc B Nguyen, Sheryl Lyss, Yen Le, Abu S Abdul-Quader, Nhan T Do, Modest Mulenga, Sebastian Hachizovu, Owen Mugurungi, Beth A Tippett Barr, Elizabeth Gonese, Tsitsi Mutasa-Apollo, Shirish Balachandra, Stephanie Behel, Trista Bingham, Duncan Mackellar, David Lowrance, Tedd V Ellerbrock
Monitoring prevalence of advanced human immunodeficiency virus (HIV) disease (i.e., CD4+ T-cell count <200 cells/μL) among persons starting antiretroviral therapy (ART) is important to understand ART program outcomes, inform HIV prevention strategy, and forecast need for adjunctive therapies.*(,)(†)(,)(§) To assess trends in prevalence of advanced disease at ART initiation in 10 high-burden countries during 2004-2015, records of 694,138 ART enrollees aged ≥15 years from 797 ART facilities were analyzed...
June 2, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28558662/evaluation-of-gene-xpert-for-routine-diagnosis-of-hiv-associated-tuberculosis-in-nigeria-a-prospective-cohort-study
#20
Maxwell Oluwole Akanbi, Chad Achenbach, Babafemi Taiwo, John Idoko, Agatha Ani, Yetunde Isa, Oche Agbaji, Christiana Ukoli, Patrick Akande, Mamoudou Maiga, Robert Leo Murphy
BACKGROUND: Xpert MTB/Rif (Xpert) is described as a game changer in tuberculosis (TB) control. We evaluated the impact of Xpert on diagnosis, time to treatment, and treatment outcome among patients with HIV associated TB in Nigeria. METHODS: Adults with HIV being evaluated for pulmonary TB (PTB) were consecutively enrolled into the study cohort. At baseline, expectorated sputa were examined using Xpert and smear microscopy for Mycobacterium tuberculosis (MTB) and acid fast bacilli, respectively...
May 30, 2017: BMC Pulmonary Medicine
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