Laiquan Zou, Yue Qi, Lei Shen, Yanyang Huang, Jiayu Huang, Zheng Xia, Mingxia Fan, Wu Fan, Guo-Bi Chai, Qing-Zhao Shi, Qidong Zhang, Chao Yan
Indole is often associated with a sweet and floral odor typical of jasmine flowers at low concentrations and an unpleasant, animal-like odor at high concentrations. However, the mechanism whereby the brain processes this opposite valence of indole is not fully understood yet. In this study, we aimed to investigate the neural mechanisms underlying indole valence encoding in conversion and nonconversion groups using the smelling task to arouse pleasantness. For this purpose, 12 conversion individuals and 15 nonconversion individuals participated in an event-related functional magnetic resonance imaging paradigm with low (low-indole) and high (high-indole) indole concentrations in which valence was manipulated independent of intensity...
April 1, 2024: Cerebral Cortex