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Labor & delivery

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https://www.readbyqxmd.com/read/29913173/diagnostic-accuracy-of-4-th-generation-architect-hiv-ag-ab-combo-assay-and-utility-of-signal-to-cutoff-ratio-to-predict-false-positive-hiv-tests-in-pregnancy
#1
Emily H Adhikari, Devin Macias, Donna Gaffney, Sarah White, Vanessa L Rogers, Donald D McIntire, Scott W Roberts
BACKGROUND: False positive HIV screening tests in pregnancy may lead to unnecessary interventions in labor. In 2014, the Centers for Disease Control and Prevention released a new algorithm for HIV diagnosis using a 4th generation screening test, which detects antibodies to HIV as well as p24 antigen and has a shorter window period compared with prior generations. A reactive screen requires a differentiation assay, and supplemental qualitative RNA testing is necessary for nonreactive differentiation assay...
June 15, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29909749/a-comparison-of-maternal-and-neonatal-outcomes-with-forceps-delivery-versus-cesarean-delivery
#2
Xiaohua Liu, Mark B Landon, Weiwei Cheng, Yan Chen
OBJECTIVE: To compare maternal and neonatal outcomes by forceps vaginal delivery versus cesarean delivery during the second stage of labor. METHODS: We conducted a retrospective cohort study in a large tertiary maternity center in Shanghai, China through 2007-2016. A total of 7046 women carrying a singleton term nonanomalous fetus with vertex presentation who underwent forceps vaginal delivery, or cesarean delivery from a low station in the second stage of labor were included...
June 18, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29909723/outcome-of-labor-among-women-admitted-at-advanced-cervical-dilatation
#3
Elie Nkwabong, Jean Marc Njemba Medou, Joseph Nelson Fomulu
OBJECTIVE: To identify in our setting the outcome of labor among women admitted at advanced cervical dilatation. METHODS: This prospective cohort study was carried out between 1 December, 2015 and 31 March, 2016. Women carrying live term singletons in vertex presentation admitted with a cervical dilatation > 5 cm (late arrival group) or ≤ 5 cm (early arrival group) were followed up till delivery. The main variables studied included mode of delivery, genital lacerations, postpartum hemorrhage (PPH)...
June 18, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29909704/the-effects-of-intravenous-dextrose-5-ringer-s-solution-and-oral-intake-on-the-duration-of-labor-stages-in-nulliparous-women-a-double-blind-randomized-controlled-trial
#4
Fatemeh Ahadi Yulghunlu, Fahimeh Sehhatie Shafaie, Mojgan Mirghafourvand, Hamideh Mohaddesi
BACKGROUND AND OBJECTIVES: Childbirth consists of a three stage period beginning with uterine contractions and ending in the expulsion of the placenta. The present study was conducted to compare the effects of Ringer's solution, dextrose solution 5% and oral intake on the duration of total labor and labor stages (primary outcome) and the frequency of oxytocin administration and prolonged labor (secondary outcome) in nulliparous women with spontaneous vaginal delivery. MATERIALS AND METHODS: The present randomized clinical trial was conducted on 201 nulliparous women in labor assigned with a randomized block design to three groups, each receiving either Ringer's solution plus oral fluids, dextrose solution 5% solution plus oral fluids or oral fluids alone...
June 18, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29909269/can-uterocervical-angles-successfully-predict-induction-of-labor-in-nulliparous-women
#5
Emrah Dagdeviren, Berna Aslan Çetin, Begum Aydogan Mathyk, Nadiye Koroglu, Elif Goknur Topcu, Mehmet Aytac Yuksel
PURPOSE: Induction of labor is a common practice in obstetrics. In recent years, a newer ultrasonographic parameter called the uterocervical angle (UCA) has been identified as a predictive tool for births. Our purpose is to investigate the role of UCA in predicting successful induction of labor. METHODS: The nulliparous term pregnancies (n:150) were grouped into successful/failed inductions of labor based on their progress into the active phase of labor after the administration of prostaglandin E2 (dinoprostone)...
June 11, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29909268/the-relationship-between-intrapartum-cerebroplacental-ratio-and-adverse-perinatal-outcomes-in-term-fetuses
#6
Natthicha Chainarong, Chusana Petpichetchian
OBJECTIVES: The cerebroplacental ratio (CPR) Doppler has been proposed as an instrument for predicting adverse perinatal outcomes particularly during antepartum period. Abnormal CPR is associated with non-reassuring fetal status requiring operative delivery, low Apgar score and neonatal complications. The aim of this study was to assess the role of CPR Doppler in the labor triage suite, so as to identify fetuses at risk for non-reassuring status as well as other adverse perinatal outcomes...
June 11, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29905542/the-features-of-the-women-s-simpathoadrenal-system-functional-state-with-risk-of-early-pregnancy-termination
#7
S Korovay
Preterm labor is an urgent medical-social and demographic issue at the present stage. A considerable number of factors affects the course of pregnancy and its outcome, their effect is realized at the level of the central nervous system through numerical metabolic interactions, where monoaminergic systems play an important role. Objective - to study the features of the sympathoadrenal system state by determining the excretion level of DOPHA, dopamine, norepinephrine and epinephrine in women's daily urine with different periods of abortion...
May 2018: Georgian Medical News
https://www.readbyqxmd.com/read/29903553/-cervical-ripening-and-labor-induction-evaluation-of-single-balloon-catheter-compared-to-double-balloon-catheter-and-dinoprostone-insert
#8
V Pez, P Deruelle, M Kyheng, C Boyon, E Clouqueur, C Garabedian
OBJECTIVE: To compare the effectiveness of single balloon catheter with double balloon catheter and dinoprostone insert for cervical ripening and labor induction on unfavourable cervix. METHODS: this is a comparative, retrospective, one-center trial. Were included singleton pregnancy in cephalic presentation. Were excluded cicatricial uterus. The outcomes were vaginal delivery rate, caesarean section rate, modification in Bishop score, time from induction to delivery, second time prostaglandin E2 resort, oxytocin administration resort, maternal or neonatal adverse events...
June 11, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29903541/endoscopic-versus-open-carpal-tunnel-release-a-detailed-analysis-using-time-driven-activity-based-costing-at-an-academic-medical-center
#9
Daniel M Koehler, Ramji Balakrishnan, Ericka A Lawler, Apurva S Shah
PURPOSE: In order to effectively improve value in health care delivery, providers must thoroughly understand cost drivers. Time-driven activity-based costing (TDABC) is a novel accounting technique that may allow for precise characterization of procedural costs. The purpose of the present study was to use TDABC to characterize costs in a high-volume, low-complexity ambulatory procedure (endoscopic vs open carpal tunnel release [CTR]), identify cost drivers, and inform opportunities for clinical improvement...
June 11, 2018: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29902983/health-providers-pass-knowledge-and-abilities-acquired-by-training-in-obstetric-emergencies-to-their-peers-the-average-treatment-on-the-treated-effect-of-pronto-on-delivery-attendance-in-mexico
#10
Jimena Fritz, Héctor Lamadrid-Figueroa, Gustavo Angeles, Alejandra Montoya, Dilys Walker
BACKGROUND: A significant proportion of newborn and maternal deaths can be prevented through simple and cost-effective strategies. The main aim of this study was to evaluate the impact of the PRONTO obstetric-emergency management training for improving evidence-based birth attendance practices among providers attending the training at 12 hospitals in three states of Mexico from 2010 to 2012, and to estimate dissemination of the training within the hospitals. METHODS: The average treatment on the treated effect of the PRONTO intervention for the probability of performing certain practices during birth attendance was estimated in a sample of 310 health providers...
June 15, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29902446/a-conceptual-framework-for-the-impact-of-obesity-on-risk-of-cesarean-delivery
#11
Anna Joy G Rogers, Lorie M Harper, Giancarlo Mari
Cesarean deliveries accounted for 32.2% of nearly 4 million births in the United States in 2014. Obesity affects a third of reproductive age women and is associated with worse cesarean delivery outcomes. Studies have shown that increasing maternal body mass index correlates linearly with cesarean delivery rates, but little is known about the potential mediating and moderating mechanisms. Thus, a conceptual framework for understanding how obesity correlates with risk of cesarean delivery is crucial to determining safe ways to reduce the cesarean delivery rate among obese gravidas...
June 11, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29900608/early-labor-cerebroplacental-ratio-assessment-in-uncomplicated-term-pregnancies-and-prediction-of-adverse-perinatal-outcomes-a-prospective-multicentre-study
#12
Andrea Dall'Asta, Tullio Ghi, Giuseppe Rizzo, Annalisa Cancemi, Filomena Aloisio, Domenico Arduini, Giuseppe Pedrazzi, Francesc Figueras, Tiziana Frusca
INTRODUCTION: Doppler ultrasound has recently been suggested to identify subclinical placental functional impairment among normal sized term fetuses. The objective of this study was to evaluate the relationship between cerebroplacental ratio (CPR) measured in early labor and perinatal and delivery outcomes in a cohort of uncomplicated singleton term pregnancies. METHODS: This was a multicentre, prospective, observational study involving three Tertiary Centres. Low risk term pregnancies, as defined by the absence of any maternal morbidity and pregnancy complication and normal ultrasound and clinical screening of the fetal growth in the third trimester, with spontaneous onset of labor were included...
June 13, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29900579/women-s-experiences-with-water-birth-a-matched-groups-prospective-study
#13
Anthony Lathrop, Carrie F Bonsack, David M Haas
BACKGROUND: Water birth has become an increasingly popular childbirth option, but has also come under scrutiny because of its possible risks and benefits. The primary objective of this study was to explore potential benefits of water birth by comparing the experiences of women who gave birth in water versus conventionally. We also compared maternal and newborn outcomes. METHODS: We performed a prospective study of 66 women who had water births and 132 who had conventional births...
June 13, 2018: Birth
https://www.readbyqxmd.com/read/29899607/improvements-in-essential-newborn-care-and-newborn-resuscitation-services-following-a-capacity-building-and-quality-improvement-program-in-three-districts-of-uttar-pradesh-india
#14
Manoja Kumar Das, Chetna Chaudhary, Sadhu Charan Mohapatra, Vinod Kumar Srivastava, Najam Khalique, Santosh Kumar Kaushal, Rajesh Khanna, Surojit Chatterji
Background: Neonatal death remains a global challenge contributing to 45% of underfive deaths. With rising institutional delivery, to accelerate decline in neonatal mortality rate (NMR) improvement in the quality of perinatal care requires attention. Objectives: This implementation research targeted improving service delivery readiness for quality of newborn care at public health facilities in three districts of Uttar Pradesh, India, with high NMR. Materials and Methods: This before-after study assessed the facility readiness and quality of newborn services at 42 health facilities...
April 2018: Indian Journal of Community Medicine
https://www.readbyqxmd.com/read/29898980/two-distinct-approaches-for-crispr-cas9-mediated-gene-editing-in-cryptococcus-neoformans-and-related-species
#15
Ping Wang
Cryptococcus neoformans and related species are encapsulated basidiomycetous fungi that cause meningoencephalitis in individuals with immune deficiency. This pathogen has a tractable genetic system; however, gene disruption via electroporation remains difficult, while biolistic transformation is often limited by lack of multiple genetic markers and the high initial cost of equipment. The approach using clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated protein 9 (Cas9) has become the technology of choice for gene editing in many organisms due to its simplicity, efficiency, and versatility...
June 27, 2018: MSphere
https://www.readbyqxmd.com/read/29898693/peripartum-fetal-distress-in-diabetic-women-a-retrospective-case-cohort-study
#16
B Castelijn, Kwp Hollander, J F Hensbergen, R G IJzerman, A W Valkenburg-van den Berg, Jwr Twisk, Cjm De Groot, Mgaj Wouters
BACKGROUND: Major concerns of pregnancies complicated by diabetes mellitus are an increased risk of adverse perinatal outcome. The objective of this study was to analyse the rate of fetal distress during labor in women with type 1, type 2 and gestational diabetes compared to control women. METHODS: A retrospective case-cohort study was conducted at the VU University Medical Center, Amsterdam; a tertiary care hospital. 117 women with type 1 diabetes, 59 women with type 2 diabetes, 303 women with gestational diabetes and 15,260 control women were included, who delivered between March 2004 and February 2014...
June 14, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29896442/sonographic-estimated-fetal-weight-among-diabetics-at-%C3%A2-34-weeks-and-composite-neonatal-morbidity
#17
Leen Al-Hafez, Michael L Pirics, Suneet P Chauhan
Objectives  The objective was to assess the composite neonatal morbidity (CNM) among diabetic women with sonographic estimated fetal weight (SEFW) at 10 to 90th versus >90th percentile for gestational age (GA). Study Design  The inclusion criteria for this retrospective study were singleton pregnancies at 34 to 41 weeks, complicated by diabetes, and that had SEFW within 4 weeks of delivery. Odds ratios (ORs) with 95% confidence intervals (CI) were calculated. Results  Among the 140 cohorts that met the inclusion criteria, 72% had SEFW at 10th to 90th percentile for GA, and 28% at >90th percentile...
April 2018: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/29895276/improvement-in-the-active-management-of-the-third-stage-of-labor-for-the-prevention-of-postpartum-hemorrhage-in-tanzania-a-cross-sectional-study
#18
Dunstan R Bishanga, John Charles, Gaudiosa Tibaijuka, Rita Mutayoba, Mary Drake, Young-Mi Kim, Marya Plotkin, Neema Rusibamayila, Barbara Rawlins
BACKGROUND: Tanzania has a maternal mortality ratio of 556 per 100,000 live births, representing 21% of all deaths of women of reproductive age. Hemorrhage, mostly postpartum hemorrhage (PPH), is estimated to cause at least 25% of maternal deaths in Tanzania. In 2008, the Ministry of Health, Community Development, Gender, Elderly and Children launched interventions to improve efforts to prevent PPH. Competency-based training for skilled birth attendants and ongoing quality improvement prioritized the practice of active management of the third stage of labor (AMTSL)...
June 13, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29895203/pregnancy-after-whipple-procedure-a-new-case-and-review-of-the-literature
#19
Giulia Magoga, Laura Felder, Francesco Palazzo, Vincenzo Berghella
BACKGROUND: Whipple procedure is a complex operation usually performed to treat periampullary neoplasms. There are only four case reports of five pregnancies after Whipple procedure, with limited evidence about how to manage pregnancy after this surgery. CASE: A 28-year-old gravida 5 Para 2022 presented to our hospital at 20 weeks with worsening depression. She had a history of Whipple for a solid pseudopapillary neoplasm of the pancreas followed by two pregnancies...
June 12, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29893994/predictive-factors-for-successful-cervical-ripening-using-a-double-balloon-catheter-after-previous-cesarean-delivery
#20
Mathilde Vital, Joséphine Grange, Aurélie Le Thuaut, Jérôme Dimet, Guillaume Ducarme
OBJECTIVE: To identify predictors of successful cervical ripening using double-balloon catheter (DBC) for labor induction among women with previous cesarean delivery (PCD) and unfavorable cervix at term. METHODS: The present prospective observational study was conducted among women who underwent cervical ripening with DBC at a French tertiary care hospital between January 1, 2014, and December 31, 2017. Inclusion criteria were PCD; singleton term fetus; cephalic presentation; and unfavorable cervix (Bishop score <6)...
June 12, 2018: International Journal of Gynaecology and Obstetrics
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