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https://www.readbyqxmd.com/read/29334994/the-relationship-between-home-and-individual-level-diet-quality-among-african-american-and-hispanic-latino-households-with-young-children
#1
Angela Kong, Linda Schiffer, Mirjana Antonic, Carol Braunschweig, Angela Odoms-Young, Marian Fitzgibbon
BACKGROUND: The quality of most Americans' diets is far from optimal. Given that many Americans consume a significant portion of calories in the home, intervening in this setting could be beneficial. However, the relationship between the home food environment and diet quality is not well understood. This study examined the relationship between diet quality at the individual level with home-level diet quality using an index that measures compliance with federal dietary guidance. METHODS: This was a cross sectional study that enrolled 97 African American and Hispanic/Latino low-income parent-child dyads...
January 15, 2018: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/29334931/in-vitro-antibacterial-and-antibiotic-modifying-activity-of-crude-extract-fractions-and-3-4-7-trihydroxyflavone-from-myristica-fragrans-houtt-against-mdr-gram-negative-enteric-bacteria
#2
Joachim K Dzotam, Ingrid Konga Simo, Gabin Bitchagno, Ilhami Celik, Louis P Sandjo, Pierre Tane, Victor Kuete
BACKGROUND: Nutmeg is the seed kernel inside the fruit of Myristica fragrans Houtt. (Myristicaceae). It possesses various pharmacological activities but is used in Cameroon only for its flavor in making cakes. The present study thus aimed to investigate the in vitro antibacterial activity and antibiotic modifying activities of crude seed kernel methanol extract (MFS), fractions (MFSa-e) as well as 3',4',7-trihydroxyflavone from Myristica fragrans against a panel of multi-drug resistant (MDR) Gram-negative bacteria...
January 15, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29329572/socio-demographic-and-lifestyle-determinants-of-dietary-patterns-in-french-speaking-switzerland-2009-2012
#3
Pedro Marques-Vidal, Gérard Waeber, Peter Vollenweider, Idris Guessous
BACKGROUND: Food intake is a complex behaviour which can be assessed using dietary patterns. Our aim was to characterize dietary patterns and associated factors in French-speaking Switzerland. METHODS: Cross-sectional study conducted between 2009 and 2012 in the city of Lausanne, Switzerland, including 4372 participants (54% women, 57.3 ± 10.3 years). Food consumption was assessed using a validated food frequency questionnaire. Dietary patterns were assessed by principal components analysis...
January 12, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29328914/rewiring-of-the-fruit-metabolome-in-tomato-breeding
#4
Guangtao Zhu, Shouchuang Wang, Zejun Huang, Shuaibin Zhang, Qinggang Liao, Chunzhi Zhang, Tao Lin, Mao Qin, Meng Peng, Chenkun Yang, Xue Cao, Xu Han, Xiaoxuan Wang, Esther van der Knaap, Zhonghua Zhang, Xia Cui, Harry Klee, Alisdair R Fernie, Jie Luo, Sanwen Huang
Humans heavily rely on dozens of domesticated plant species that have been further improved through intensive breeding. To evaluate how breeding changed the tomato fruit metabolome, we have generated and analyzed a dataset encompassing genomes, transcriptomes, and metabolomes from hundreds of tomato genotypes. The combined results illustrate how breeding globally altered fruit metabolite content. Selection for alleles of genes associated with larger fruits altered metabolite profiles as a consequence of linkage with nearby genes...
January 11, 2018: Cell
https://www.readbyqxmd.com/read/29322920/investigation-and-identification-of-functional-post-translational-modification-sites-associated-with-drug-binding-and-protein-protein-interactions
#5
Min-Gang Su, Julia Tzu-Ya Weng, Justin Bo-Kai Hsu, Kai-Yao Huang, Yu-Hsiang Chi, Tzong-Yi Lee
BACKGROUND: Protein post-translational modification (PTM) plays an essential role in various cellular processes that modulates the physical and chemical properties, folding, conformation, stability and activity of proteins, thereby modifying the functions of proteins. The improved throughput of mass spectrometry (MS) or MS/MS technology has not only brought about a surge in proteome-scale studies, but also contributed to a fruitful list of identified PTMs. However, with the increase in the number of identified PTMs, perhaps the more crucial question is what kind of biological mechanisms these PTMs are involved in...
December 21, 2017: BMC Systems Biology
https://www.readbyqxmd.com/read/29315507/lifestyle-factors-and-subsequent-ischemic-heart-disease-risk-after-hematopoietic-cell-transplantation
#6
Kasey J Leger, K Scott Baker, Kara L Cushing-Haugen, Mary E D Flowers, Wendy M Leisenring, Paul J Martin, Jason A Mendoza, Kerryn W Reding, Karen L Syrjala, Stephanie J Lee, Eric J Chow
BACKGROUND: The objective of this study was to evaluate whether modifiable cardiovascular risk conditions and lifestyle factors were temporally associated with an increased risk for ischemic heart disease and overall mortality in a cohort of hematopoietic cell transplantation (HCT) survivors. METHODS: HCT recipients who had survived for ≥1 year, were ≥20 years old, and had undergone transplantation between 1970 and 2010 at a transplant referral center were surveyed in 2010-2011 about cardiovascular health and lifestyle factors (n = 3833)...
January 9, 2018: Cancer
https://www.readbyqxmd.com/read/29314841/grape-berry-acclimation-to-excessive-solar-irradiance-leads-to-repartitioning-between-major-flavonoid-groups
#7
Noam Reshef, Nurit Agam, Aaron Fait
Warm viticulture regions are associated with inferior wines, resulting from the interaction between microclimate and fruit biochemistry. Solar irradiance triggers biosynthetic processes in the fruit, and dominates its thermal balance. Therefore, deciphering its impact on fruit metabolism is pivotal to develop strategies for fruit protection, and ameliorate its quality traits. Here, we modified light quality and intensity in the fruit-zone and integrated micrometeorology with grape and wine metabolomics, allowing a complete assessment, from field to bottle...
January 9, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29310862/a-review-on-the-hybrids-of-hydroxycinnamic-acid-as-multi-target-directed-ligands-against-alzheimer-s-disease
#8
REVIEW
Xiao Zhang, Xixin He, Qiuhe Chen, Junfeng Lu, Simona Rapposelli, Rongbiao Pi
Alzheimer's disease (AD), a complex chronic progressive central nervous system degenerative disease and a public health problem of the world, often characters cognitive dysfunction accompaning aggression and depression, and may lead to death. More attentions should be paid on it because there is no modified strategy against AD till now. AD is featured with the loss of cholinergic neurons, the amyloid-beta peptide (Aβ) plaques and the neurofibrillary tangles and several hypotheses were established to explain the pathogenesis of AD...
December 26, 2017: Bioorganic & Medicinal Chemistry
https://www.readbyqxmd.com/read/29304763/attributable-causes-of-colorectal-cancer-in-china
#9
Meng-Jia Gu, Qiu-Chi Huang, Cheng-Zhen Bao, Ying-Jun Li, Xiao-Qin Li, Ding Ye, Zhen-Hua Ye, Kun Chen, Jian-Bing Wang
BACKGROUND: Colorectal cancer is the 4th common cancer in China. Most colorectal cancers are due to modifiable lifestyle factors, but few studies have provided a systematic evidence-based assessment of the burden of colorectal cancer incidence and mortality attributable to the known risk factors in China. METHODS: We estimated the population attributable faction (PAF) for each selected risk factor in China, based on the prevalence of exposure around 2000 and relative risks from cohort studies and meta-analyses...
January 5, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29303081/a-new-approach-to-enhance-the-solubility-of-famotidine-tablet-by-using-naturally-isolated-pear-starch
#10
Anjali Kushwaha, Manjul Pratap Singh
PURPOSE- The solubility of drug is affected by various excipients presents in formulation. In case of tablets the role of binders is very important for solubility of dosage form as well as drug. Thus in following study an attempt is made to improve the solubility and dissolution rate of a drug by use of natural excipients. The starch was extracted from the Pear fruits and used as a binder in different concentrations, in famotidine tablets and evaluate them. There are some recent patents on modified starch (WO2011002730A1), directly compressed starch (US6455069B1), pre-compacted starches (US4072535A), which helped in my study...
January 4, 2018: Recent Patents on Drug Delivery & Formulation
https://www.readbyqxmd.com/read/29297687/anthocyanin-management-in-fruits-by-fertilization
#11
Mareike Jezek, Christian Zörb, Nikolaus Merkt, Christoph-Martin Geilfus
Anthocyanins are water-soluble vacuolar plant pigments that are mainly synthesized in epidermal layers and the flesh of fruits such as apples, cherries, grapes, and other berries. Because of their attractive red to purple coloration and their health-promoting potential, anthocyanins are significant determinants for the quality and market value of fruits and fruit-derived products. In crops, anthocyanin accumulation in leaves can be caused by nutrient deficiency which is usually ascribed to insufficient nitrogen or phosphorous fertilization...
January 3, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29287382/the-validated-and-sensitive-hplc-dad-method-for-determination-of-patulin-in-strawberries
#12
Ilona Sadok, Agnieszka Szmagara, Magdalena Maria Staniszewska
This work outlines HPLC coupled with DAD detection for accurate quantification of patulin (mycotoxin) in strawberries. The optimized extraction of fruit samples through the modified QuEChERS technique in acetonitrile acidified with acetic acid (1%, v/v) and citrate-buffered salts followed by dispersive solid phase extraction using a primary secondary amine and graphitized carbon is described. The method presents LOD and LOQ of 1.5 and 5µg/kg, respectively and has been validated in strawberry matrix at three concentration levels (5, 10 and 50µg/kg), according to SANTE/11945/2015 and the 2002/657/EC Decision requirements...
April 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29287349/aroma-modulation-of-cabernet-gernischt-dry-red-wine-by-optimal-enzyme-treatment-strategy-in-winemaking
#13
Wei-Xuan Sun, Kai Hu, Jun-Xiang Zhang, Xiao-Lin Zhu, Yong-Sheng Tao
Cabernet Gernischt (CG) is a famous Chinese wine grape cultivar, the red wine of which is known for its green trait, especially when produced from grapes cultivated in regions with monsoon climate. To modify CG wine aroma, three enzyme preparations (H. uvarum extracellular enzyme, AR2000, and pectinase) were introduced in different winemaking stages with Saccharomyces cerevisiae. Free and bound aroma compounds in young wines were detected using headspace solid-phase micro-extraction and gas chromatography-mass spectrometry, and aroma characteristics were quantified by trained panelists...
April 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29276506/escherichia-coli-o157-h7-converts-plant-derived-choline-to-glycine-betaine-for-osmoprotection-during-pre-and-post-harvest-colonization-of-injured-lettuce-leaves
#14
Russell A Scott, Roger Thilmony, Leslie A Harden, Yaguang Zhou, Maria T Brandl
Plant injury is inherent to the production and processing of fruit and vegetables. The opportunistic colonization of damaged plant tissue by human enteric pathogens may contribute to the occurrence of outbreaks of foodborne illness linked to produce. Escherichia coli O157:H7 (EcO157) responds to physicochemical stresses in cut lettuce and lettuce lysates by upregulation of several stress response pathways. We investigated the tolerance of EcO157 to osmotic stress imposed by the leakage of osmolytes from injured lettuce leaf tissue...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29273039/including-pork-in-the-mediterranean-diet-for-an-australian-population-protocol-for-a-randomised-controlled-trial-assessing-cardiovascular-risk-and-cognitive-function
#15
Alexandra T Wade, Courtney R Davis, Kathryn A Dyer, Jonathan M Hodgson, Richard J Woodman, Hannah A D Keage, Karen J Murphy
BACKGROUND: The Mediterranean diet is characterised by the high consumption of extra virgin olive oil, fruits, vegetables, grains, legumes and nuts; moderate consumption of fish, poultry, eggs and dairy; and low consumption of red meat and sweets. Cross sectional, longitudinal and intervention studies indicate that a Mediterranean diet may be effective for the prevention of cardiovascular disease and dementia. However, previous research suggests that an Australian population may find red meat restrictions difficult, which could affect long term sustainability of the diet...
December 22, 2017: Nutrition Journal
https://www.readbyqxmd.com/read/29243815/effect-of-grinding-at-modified-atmosphere-or-vacuum-on-browning-antioxidant-capacities-and-oxidative-enzyme-activities-of-apple
#16
Ah-Na Kim, Kyo-Yeon Lee, Hyun-Jin Kim, Jiyeon Chun, William L Kerr, Sung-Gil Choi
This study evaluated the effects of grinding at atmospheric pressure (control), under vacuum (∼2.67 kPa), or with modified atmosphere (N2 and CO2 ) on the browning, antioxidant activity, phenolics, and oxidative enzyme activity of apples as a function of time. The control group was affected most, showing distinct browning and losing most of the antioxidant activity and concentrations of the main phenolic compounds. The modified atmosphere groups retained color, antioxidant activity, and phenolic compounds better than the control group...
December 15, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/29242189/secreted-heme-peroxidase-from-dictyostelium-discoideum-insights-into-catalysis-structure-and-biological-role
#17
Andrea Nicolussi, Joe Dan Dunn, Georg Mlynek, Marzia Bellei, Marcel Zámocký, Gianantonio Battistuzzi, Kristina Djinovic-Carugo, Paul G Furtmüller, Thierry Soldati, Christian Obinger
Oxidation of halides and thiocyanate by heme peroxidases to antimicrobial oxidants is an important cornerstone in the innate immune system of mammals. Interestingly, phylogenetic and physiological studies suggest that homologous peroxidases are already present in mycetozoan eukaryotes such as Dictyostelium discoideum This social amoeba kills bacteria via phagocytosis for nutrient acquisition at its single-cell stage and for antibacterial defense at its multicellular stages. Here we demonstrate that peroxidase A from D...
December 14, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29241318/polyphenolic-content-antiradical-activity-stability-and-microbiological-quality-of-elderberry-sambucus-nigra-l-extracts
#18
Barbara Pliszka
BACKGROUND: The pharmaceutical and food industries expect detailed knowledge on the physicochemical properties of elderberry fruit extracts, their stability and microbiological quality, as well as the polyphenol content in elderberry cultivars. The characteristics of the extracts might be additionally modified by citric acid, which improves the stability of anthocyanins and protects processed fruits and syrups from pathogenic microorganisms. The choice of the method with citric acid was a consequence of the physicochemical charac teristics of elderberry pigments, which are not stable under the effect of light in alcoholic solutions...
October 2017: Acta Scientiarum Polonorum. Technologia Alimentaria
https://www.readbyqxmd.com/read/29240233/blue-honeysuckle-lonicera-caerulea-subsp-edulis-turcz-ex-herder-hult%C3%A3-n-berries-and-changes-in-their-ingredients-across-different-locations
#19
Mateja Senica, Martina Bavec, Franci Stampar, Maja Mikulic-Petkovsek
BACKGROUND: Interest in organic blue honeysuckle berries has increased in recent years. They are rich in various health promoting compounds, which are sensitive to different environmental factors and are modified during the growing season. RESULTS: Honeysuckle berries from different locations significantly differed in contents of primary and secondary metabolites. The location Ogulin, with the highest altitude and, consequently, high UV-radiation, had the highest phenolics content (259...
December 14, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29230155/methodological-considerations-in-a-pilot-study-on-the-effects-of-a-berry-enriched-smoothie-on-children-s-performance-in-school
#20
Ulla Rosander, Kimmo Rumpunen, Viktoria Olsson, Mikael Åström, Pia Rosander, Karin Wendin
Berries contain bioactive compounds that may affect children's cognitive function positively, while hunger and thirst during lessons before lunch affect academic performance negatively. This pilot study addresses methodological challenges in studying if a berry smoothie, offered to schoolchildren as a mid-morning beverage, affects academic performance. The objective was to investigate if a cross-over design can be used to study these effects in a school setting. Therefore, in order to investigate assay sensitivity, 236 Swedish children aged 10-12 years were administered either a berry smoothie (active) or a fruit-based control beverage after their mid-morning break...
2017: Food & Nutrition Research
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