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https://www.readbyqxmd.com/read/29470470/limiting-complication-rates-in-implant-based-breast-reconstruction
#1
Michelle B Locke, William LE Malins, Jia Le See, John Kenealy
BACKGROUND: External beam radiotherapy (XRT) to the breast has been shown to increase complication rates in women undergoing implant-based breast reconstruction (IBBR). Owing to concerns about high complication and failure rates, our department began to favour autologous reconstructive in patients requiring XRT in 2013. This study assesses the outcomes of IBBR prior to and following this policy change. METHODS: The records of all patients who underwent first-stage IBBR in 2012 and 2013 in our department were reviewed...
February 23, 2018: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29466511/comparison-between-different-methods-of-breast-implant-volume-choice-and-degree-of-postoperative-satisfaction
#2
Rafael Daibert DE Souza Motta, Ana Claudia Weck Roxo, Fabio Xerfan Nahas, Fernando Serra-Guimarães
OBJECTIVES: to assess the degree of patient satisfaction after undergoing breast augmentation and compare three different, easy, inexpensive and universal methods of preoperative choice of breast implant volume. METHODS: a prospective study was carried out at University Hospital Pedro Ernesto of State University of Rio de Janeiro, in 94 women from Rio de Janeiro, aged 18 to 49 years, submitted to breast augmentation mammaplasty with breast implant due to hypomastia...
February 19, 2018: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/29464176/latissimus-dorsi-and-immediate-fat-transfer-lift-for-complete-autologous-breast-reconstruction
#3
James M Economides, David H Song
Background: Despite the popularity of latissimus dorsi (LD) flap in breast reconstruction, a breast implant is often necessary to achieve sufficient volume. Prior reports describe fat grafting to the LD flap as a secondary procedure to correct contour deformities and improve volume. Our institution has instituted autologous breast reconstruction with an LD flap and immediate fat transfer (LIFT). Methods: A retrospective review of all patients undergoing the LIFT procedure was undertaken...
January 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29464161/complications-following-nipple-sparing-mastectomy-and-immediate-acellular-dermal-matrix-implant-based-breast-reconstruction-a-systematic-review-and-meta-analysis
#4
Lene Nyhøj Heidemann, Gudjon L Gunnarsson, C Andrew Salzberg, Jens Ahm Sørensen, Jørn Bo Thomsen
Background: Acellular dermal matrix was introduced in breast reconstruction in 2001 and is gradually becoming a standard component for immediate breast reconstruction and nipple-sparing mastectomy. The reconstructive technique allows for improved aesthetic outcomes. However, there seems to be uncertainty regarding complication rates. The aim of this review was to systematically evaluate complication rates related to this method. Methods: This systematic review was conducted according to the recommendations outlined in the Cochrane Handbook for reviews and reported in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement...
January 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29464155/single-stage-breast-reconstruction-using-an-all-in-one-adjustable-expander-implant
#5
Alain J Azzi, Dino Zammit, Lucie Lessard
Background: When tissue expansion is necessary in breast reconstruction, a single-stage approach is possible using adjustable expander/implants, with or without the use of acellular dermal matrix. We aimed to present the senior author's single-stage experience over a period of 12 years using combined expander/implants in breast reconstruction. Methods: This is a Single-institution, retrospective review of breast reconstruction with combined expander/implants from 2002 to 2014...
January 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29462290/commentary-on-breast-erythema-in-a-patient-with-breast-implant-associated-anaplastic-large-cell-lymphoma-a-case-report-discussing-cutaneous-manifestations
#6
Anand K Deva
No abstract text is available yet for this article.
February 15, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29456260/rf-safety-evaluation-of-a-breast-tissue-expander-device-for-mri-numerical-simulation-and-experiment
#7
Bu S Park, Amir Razjouyan, Leonardo M Angelone, Brent McCright, Sunder S Rajan
This study describes the MRI-related radio frequency (RF) safety evaluation of breast tissue expander devices to establish safety criteria. Numerical simulations and experimental measurements were performed at 64 MHz with a gel phantom containing a breast expander. Additionally, computational modeling was performed (64 and 128 MHz) with an adult female model, containing a virtually implanted breast tissue expander device for four imaging landmark positions. The presence of the breast tissue expander device led to significant alterations in specific absorption rate (SAR) and|B1 + |distributions...
October 2017: IEEE Transactions on Electromagnetic Compatibility
https://www.readbyqxmd.com/read/29455110/nipple-sparing-bilateral-prophylactic-mastectomy-and-immediate-reconstruction-with-tiloop-%C3%A2-bra-mesh-in-brca1-2-mutation-carriers-a-prospective-study-of-long-term-and-patient-reported-outcomes-using-the-breast-q
#8
D Casella, G Di Taranto, M Marcasciano, S Sordi, A Kothari, T Kovacs, F Lo Torto, E Cigna, D Ribuffo, C Calabrese
BACKGROUND: Although demand for prophylactic mastectomy is increasing over time among women at a high risk for breast cancer, there is a paucity of studies on long term patient-reported outcomes after this procedure. METHODS: Between January 2011 and January 2015, 46 patients documented BRCA1/2 mutation carriers, eligible for prophylactic nipple-sparing mastectomy (NSM) and immediate breast prosthetic reconstruction were registered at our institutions. Patients underwent NSM and subcutaneous reconstruction with implant covered by a titanium-coated polypropylene mesh (TiLoop® )...
February 15, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29454887/metabolomic-analysis-uncovered-an-association-of-serum-phospholipid-levels-with-estrogen-induced-mammary-tumors-in-female-aci-seg-rats
#9
Yoshinori Okamoto, Akira Aoki, Koji Ueda, Hideto Jinno
Estrogen is reported to be involved in mammary tumorigenesis. To unveil metabolic signatures for estrogen-induced mammary tumorigenesis, we carried out serum metabolomic analysis in an estrogen-induced mammary tumor model, female August Copenhagen-Irish/Segaloff (ACI/Seg) rats, using liquid chromatography-mass spectrometry. In contrast to the control group, all rats with an implanted 17β-estradiol (E2) pellet developed mammary tumors during this experiment. E2 treatment significantly suppressed body weight gain...
February 15, 2018: Toxicology Letters
https://www.readbyqxmd.com/read/29452341/betadine-and-breast-implants
#10
Mark L Jewell, William P Adams
In the fourth quarter of 2017, the US FDA reviewed and approved a request by one of the breast implant manufacturers for a change in the Directions for Use (DFU) that removed warnings regarding the use of Betadine (povidone-iodine [PI] 10% solution, 1% available iodine [Purdue Frederick Company, Stamford, CT], also available in generic formulations [Aplicare, Inc., Meriden, CT]). Previously, in 2000, there were concerns by the FDA that PI would degrade the silicone elastomer shell. This change in the DFU represents an important advance that will benefit patients through the permitted use of PI to reduce the risk of bacterial contamination of implant surfaces...
February 14, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29445921/spontaneous-regression-and-resolution-of-breast-implant-associated-anaplastic-large-cell-lymphoma-implications-for-research-diagnosis-and-clinical-management
#11
Daniel Fleming, Jason Stone, Patrick Tansley
BACKGROUND: First described in 1997, breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) was recognised by the World Health Organisation in 2016 as a specific disease. It typically presents as a late seroma-containing atypical, monoclonal T cells which are CD30+ and anaplastic lymphoma kinase negative. Until recently, it was thought that the disease was very rare. However, it is being diagnosed increasingly frequently with 56 cases confirmed in Australia by September 2017 and the estimated incidence revised from 1 in 300,000 to between 1 in 1000 and 1 in 10,000 patients with bilateral implants...
February 14, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29443834/does-2-stage-implant-based-breast-reconstruction-allow-for-a-larger-volume-of-the-definite-implant-compared-with-1-stage-reconstruction
#12
R C Killaars, J Hommes, R R van der Hulst, H J Tielemans, V L Negenborn, A Piatkowski
INTRODUCTION: Breast reconstruction using implants is still the main breast reconstruction technique worldwide. Current debate within implant-based breast reconstruction is whether to perform a 1-stage (direct implant) or 2-stage (tissue expander/implant) reconstruction. Volume differences between a woman's native breast and changes in volume after breast reconstruction might be an important factor for a patient's choice between these types of reconstruction. Three-dimensional imaging facilitates objective breast volume estimates...
February 13, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29442288/updates-of-peripheral-t-cell-lymphomas-based-on-the-2017-who-classification
#13
REVIEW
Parwiz J Siaghani, Joo Y Song
PURPOSE OF REVIEW: This review will describe and update the readers on the recent changes of the 2017 WHO classification in regard to peripheral T cell lymphomas. RECENT FINDINGS: Significant advances in molecular studies have resulted in revisions of the classification as well as introduction of provisional entities (such as breast implant-associated ALCL, nodal PTCL with TFH phenotype). Major advances in molecular and gene expression profiling have expanded our knowledge of T cell lymphomas, including updates in the diagnostic criteria and sub-classification which will facilitate in improving patient care and research...
February 14, 2018: Current Hematologic Malignancy Reports
https://www.readbyqxmd.com/read/29437878/essential-role-of-polo-like-kinase-1-plk1-oncogene-in-tumor-growth-and-metastasis-of-tamoxifen-resistant-breast-cancer
#14
Sung Baek Jeong, Ji Hye Im, Jeong-Hoon Yoon, Quyen Thu Bui, Sung Chul Lim, Joon Myong Song, Yumi Shim, Jieun Yun, Janghee Hong, Keon Wook Kang
The most common therapy for estrogen receptor-positive breast cancer is anti-hormone therapy such as tamoxifen (TAM). However, acquisition of resistance to TAM in one-third of patients presents a serious clinical problem. Polo-like kinase 1 (Plk1) is a key oncogenic regulator of completion of G2/M phase of the cell cycle. We assessed Plk1 expression in five chemoresistant cancer cell types and found that Plk1 and its downstream phosphatase Cdc25c were selectively overexpressed in TAM-resistant MCF-7 (TAMR-MCF-7) breast cancer cells...
February 7, 2018: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/29434662/novel-devices-for-implant-based-breast-reconstruction-is-the-use-of-meshes-to-support-the-lower-pole-justified-in-terms-of-benefits-a-review-of-the-evidence
#15
REVIEW
Lorna Jane Cook, Tibor Kovacs
The use of novel devices such as acellular dermal matrices (ADMs) to support the lower pole in implant-based breast reconstructions (IBBRs) has been described as one of the most important advances in breast reconstructive surgery following mastectomy. However, the majority of outcomes studies focus primarily on providing evidence for the rates of short-term complications associated with their use, as opposed to their reported benefits. Given the high costs associated with using ADMs, together with an increasing number of alternative, cheaper synthetic products entering the market, it is important to clarify whether their use is actually justified and whether the alternative products offer equivalent or superior outcomes...
2018: Ecancermedicalscience
https://www.readbyqxmd.com/read/29423974/usefulness-of-rapiplug-in-nipple-reconstruction-to-improve-nipple-projection
#16
Joon Seok Lee, Joon Hyun Kwon, Jeong Woo Lee, Kang Young Choi, Ho Yun Chung, Byung Chae Cho, Jung Dug Yang
BACKGROUND: The final stage of breast reconstruction after mastectomy for breast cancer is nipple reconstruction. However, a consistent and reliable method resulting in the most ideal aesthetic results has yet to be clarified. This study analysed the long-term outcomes of nipple reconstruction using Rapiplug. METHODS: Forty-one patients who underwent immediate breast reconstruction after mastectomy between January 2014 and February 2017 were enrolled. Nipple reconstruction was performed with C-V flap and Hammond flap, and hat-shaped Rapiplug was implanted at the flap core...
February 8, 2018: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29420643/immunophenotypic-characterization-of-human-t-cells-after-in-vitro-exposure-to-different-silicone-breast-implant-surfaces
#17
Giuseppe Cappellano, Christian Ploner, Susanne Lobenwein, Sieghart Sopper, Paul Hoertnagl, Christina Mayerl, Nikolaus Wick, Gerhard Pierer, Georg Wick, Dolores Wolfram
The most common complication of silicone breast implants is capsular contracture (massive scar formation around the implant). We postulate that capsular contracture is always a sequel to inflammatory processes, with both innate and adaptive immune mechanisms participating. In general, fibroblasts and macrophages have been used as cell types to evaluate in vitro the biocompatibility of breast implant surfaces. Moreover, also T cells have been found at the implant site at the initial stage of fibrous capsule formation...
2018: PloS One
https://www.readbyqxmd.com/read/29419662/the-role-of-postmastectomy-radiation-therapy-in-patients-with-immediate-prosthetic-breast-reconstruction-a-meta-analysis
#18
Yun Pu, Tong-Chun Mao, Yi-Ming Zhang, Shao-Liang Wang, Dong-Li Fan
OBJECTIVE: The controversy remains as to whether immediate prosthetic breast reconstruction with postmastectomy radiation therapy (PMRT) is associated with acceptable complications and aesthetic outcomes. The aim of this meta-analysis was to provide a pooled analysis of comparative clinical studies that evaluated breast cancer patients who were treated with a mastectomy and an immediate prosthetic breast reconstruction to compare the complications and satisfaction of those who underwent or did not undergo PMRT...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29411424/positional-relationship-between-the-pectoralis-major-and-external-abdominal-oblique-muscles-for-consideration-during-dual-plane-breast-augmentation
#19
Young-Chun Gil, Kang-Woo Lee, Doo-Yeoul Chang, Sang-Hyuk Park, Hee-Jin Kim, Hyoung-Moon Kim
INTRODUCTION: During dual plane breast augmentation (DPBA), the costal origin of the pectoralis major (the PM) should be cut to ensure appropriate coverage and positioning of an implant. However, surgeons sometimes make inappropriate planar incisions and insufficient muscular incisions because the external abdominal oblique (the EAO) muscle partially overlaps the lateral portion of the PM. The goal of this study was to clarify the positional relationship between the PM and EAO with the aim of improving the accuracy of implant and muscular incisions during DPBA...
February 7, 2018: Clinical Anatomy
https://www.readbyqxmd.com/read/29407145/simple-fabrication-of-rough-halloysite-nanotubes-coatings-by-thermal-spraying-for-high-performance-tumor-cells-capture
#20
Rui He, Mingxian Liu, Yan Shen, Rong Liang, Wei Liu, Changren Zhou
Here, we reported a fast, low-cost, and effective fabrication method of large-area and rough halloysite nanotubes (HNTs) coatings by thermal spraying of HNTs ethanol dispersions. A uniform HNTs coating with high transparence is achieved with tailorable surface roughness and thickness. Compared with normal cells, the tumor cells can be captured effectively with high capture yield by the HNTs coatings (expect HeLa cells), which is attributed to the enhanced topographic interactions between HNTs coating and cancer cells...
April 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
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