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https://www.readbyqxmd.com/read/29356302/fast-publication-a-must-for-a-journal
#1
EDITORIAL
Paolo Pozzilli
As Diabetes/Metabolism: Research & Reviews (DMRR) begins its transition to a new editorial team, incoming Editor-in-Chief, Dr Paolo Pozzilli, reflects on the lessons learned from the past editorship and envisions the future of the journal. In today's fast-paced world, a medical journal should be fast in communicating decisions. Authors are eager to publish their work as fast as possible, and a journal must guarantee this, whilst at the same time ensuring a rigorous peer-review process. With this in mind, we hope to help the diabetes scientific community...
January 2018: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/29326430/emt-in-cancer
#2
REVIEW
Thomas Brabletz, Raghu Kalluri, M Angela Nieto, Robert A Weinberg
Similar to embryonic development, changes in cell phenotypes defined as an epithelial to mesenchymal transition (EMT) have been shown to play a role in the tumorigenic process. Although the first description of EMT in cancer was in cell cultures, evidence for its role in vivo is now widely reported but also actively debated. Moreover, current research has exemplified just how complex this phenomenon is in cancer, leaving many exciting, open questions for researchers to answer in the future. With these points in mind, we asked four scientists for their opinions on the role of EMT in cancer and the challenges faced by scientists working in this fast-moving field...
January 12, 2018: Nature Reviews. Cancer
https://www.readbyqxmd.com/read/29303114/comparative-analysis-of-germanium-silicon-quantum-dots-formation-on-si-100-si-111-and-sn-si-100-surfaces
#3
Kirill Lozovoy, Andrey Kokhanenko, Alexander Voitsekhovskii
In this paper theoretical modeling of formation and growth of germanium-silicon quantum dots in the method of molecular beam epitaxy (MBE) on different surfaces is carried out. Silicon substrates with crystallographic orientations (100) and (111) are considered. Special attention is paid to the question of growth of quantum dots on the silicon surface covered by tin, since germanium-silicon-tin system is extremely important for contemporary nano- and optoelectronics: for creation of photodetectors, solar cells, light-emitting diodes, and fast-speed transistors...
February 2, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29239708/psychoanalytic-thoughts-on-the-european-refugee-crisis-and-the-other
#4
Vamık D Volkan
There are many aspects-political, economic, legal, medical, cultural, religious-of the present refugee crisis in Europe. Difficulties at border crossings, settlement programs, life-saving issues, and security measures come to mind immediately, but the refugee crisis also needs to be examined from a psychological angle. This paper outlines psychoanalytic findings on voluntary and forced immigration and human responses to the Other. Change in the twenty-first century is occurring at an unprecedented pace and scale...
December 2017: Psychoanalytic Review
https://www.readbyqxmd.com/read/29234986/exertional-rhabdomyolysis-leading-to-acute-kidney-injury-when-genetic-defects-are-diagnosed-in-adult-life
#5
David Cucchiari, Irene Colombo, Ottavia Amato, Manuel Alfredo Podestà, Francesco Reggiani, Rossella Valentino, Irene Faravelli, Silvia Testolin, Maurizio Moggio, Salvatore Badalamenti
Rhabdomyolysis is a common cause of acute kidney injury (AKI) that is usually triggered by trauma. However, less common causes of rhabdomyolysis may precipitate AKI as well, possibly representing a diagnostic challenge even for the experienced nephrologist. Genetic defects of muscle metabolism represent one of these causes and can be overlooked in adults, since these diseases usually become apparent in childhood. We present here a case in which an adult patient with severe exertional rhabdomyolysis leading to AKI was finally diagnosed with a genetic defect of lipid metabolism...
December 12, 2017: CEN Case Reports
https://www.readbyqxmd.com/read/29230431/initial-experience-and-usage-patterns-with-the-owlet-smart-sock-monitor-in-47-495-newborns
#6
Michelle I Dangerfield, Kenneth Ward, Luke Davidson, Milena Adamian
We report the largest experience, to our knowledge, of home cardiorespiratory monitoring in 47,495 newborns using the novel Owlet Smart Sock (OSS) technology (October 2015 to May 2017). On average, 47,495 newborns were monitored for 6 months, 4.5 d/wk, 9.9 h/d. Continuous readings of oxygen saturation and heart rate were obtained from 39,626 full-term newborns. OSS users were likely first-time parents in their 30s with at least a college degree; 37% had a healthcare professional in the family; and 28% were at or below median income level per the US Census Bureau...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/29218049/immunoglobulins-g-from-sera-of-amyotrophic-lateral-sclerosis-patients-induce-oxidative-stress-and-upregulation-of-antioxidative-system-in-bv-2-microglial-cell-line
#7
Milena Milošević, Katarina Milićević, Iva Božić, Irena Lavrnja, Ivana Stevanović, Dunja Bijelić, Marija Dubaić, Irena Živković, Zorica Stević, Rashid Giniatullin, Pavle Andjus
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder with a very fast progression, no diagnostic tool for the presymptomatic phase, and still no effective treatment of the disease. Although ALS affects motor neurons, the overall pathophysiological condition points out to the non-cell autonomous mechanisms, where astrocytes and microglia play crucial roles in the disease progression. We have already shown that IgG from sera of ALS patients (ALS IgG) induce calcium transients and an increase in the mobility of acidic vesicles in cultured rat astrocytes...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29183908/modulation-of-glp-1-levels-by-a-genetic-variant-that-regulates-the-cardiovascular-effects-of-intensive-glycemic-control-in-accord
#8
Hetal S Shah, Mario Luca Morieri, Santica M Marcovina, Ronald J Sigal, Hertzel C Gerstein, Michael J Wagner, Alison A Motsinger-Reif, John B Buse, Peter Kraft, Josyf C Mychaleckyj, Alessandro Doria
OBJECTIVE: A genome-wide association study in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial identified two markers (rs57922 and rs9299870) that were significantly associated with cardiovascular mortality during intensive glycemic control and could potentially be used, when combined into a genetic risk score (GRS), to identify patients with diabetes likely to derive benefit from intensive control rather than harm. The aim of this study was to gain insights into the pathways involved in the modulatory effect of these variants...
November 28, 2017: Diabetes Care
https://www.readbyqxmd.com/read/29160524/a-fatal-case-of-tuberculous-meningitis-in-a-child-with-juvenile-idiopathic-arthritis-a-diagnostic-challenge
#9
Zumrut Sahbudak Bal, Pinar Yazici, Semra Sen, Cenk Eraslan, Cengiz Cavusoglu, Bulent Karapinar, Fadil Vardar
The prognosis of tuberculous meningitis, a rare form of extrapulmonary tuberculosis, depends on the stage of treatment initiation. We report a fatal case of tuberculous meningitis. The patient had received successive tumor necrosis factor (TNF) antagonists and abatacept to treat juvenile idiopathic arthritis, with negative results for polymerase chain reaction and acid-fast bacilli on smear, had normal cerebrospinal fluid (CSF) adenosine deaminase and glucose levels. Six weeks post-admission, the CSF culture demonstrated Mycobacterium tuberculosis...
September 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29033871/sense-of-place-fast-and-slow-the-potential-contributions-of-affordance-theory-to-sense-of-place
#10
Christopher M Raymond, Marketta Kyttä, Richard Stedman
Over the past 40 years, the sense of place concept has been well-established across a range of applications and settings; however, most theoretical developments have "privileged the slow." Evidence suggests that place attachments and place meanings are slow to evolve, sometimes not matching material or social reality (lag effects), and also tending to inhibit change. Here, we present some key blind spots in sense of place scholarship and then suggest how a reconsideration of sense of place as "fast" and "slow" could fill them...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28988431/hearing-loss-on-social-media-who-is-winning-hearts-and-minds
#11
Matthew G Crowson, Debara L Tucci, David Kaylie
OBJECTIVES/HYPOTHESIS: To analyze specific patterns of Twitter usage using common references to hearing loss, and characterize the virtual public that comprises the hearing loss community to inform hearing loss stakeholders for opportunities for engagement and outreach. STUDY DESIGN: Social media network analysis. METHODS: Twitter tweets were sampled from July 2016 to September 2016 using #hearing, #hearingloss, #deaf, #hearingimpairment, #hardofhearing, #deafness, #hearingmatters, #hearinghealth, and #hearingimpaired tags...
October 8, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28963884/yoga-mindfulness-based-stress-reduction-and-stress-related-physiological-measures-a-meta-analysis
#12
REVIEW
Michaela C Pascoe, David R Thompson, Chantal F Ski
BACKGROUND AND OBJECTIVES: Practices that include yoga asanas and mindfulness-based stress reduction for the management of stress are increasingly popular; however, the neurobiological effects of these practices on stress reactivity are not well understood. Many studies investigating the effects of such practices fail to include an active control group. Given the frequency with which people are selecting such interventions as a form of self-management, it is important to determine their effectiveness...
December 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28923164/not-just-tea-and-biscuits-the-gold-coast-primary-health-network-process-of-designing-implementing-and-operating-a-community-advisory-council
#13
Jessica McClean, Kellie Trigger
Consumers are fast being acknowledged as a critical voice in the creation of sustainable health systems, and their ability and willingness to participate must be kept in mind by those eager to engage them. Federal health reform in Australia has mandated the formal involvement of communities in primary care through advisory committees in the newly established Primary Health Networks. Although there is clear progression towards increased consumer participation in Australia's health services, scope exists to improve the evidence base around identifying and implementing the most appropriate approach in different settings...
September 19, 2017: Australian Journal of Primary Health
https://www.readbyqxmd.com/read/28886468/do-drives-drive-the-train-of-thought-effects-of-hunger-and-sexual-arousal-on-mind-wandering-behavior
#14
Jan Rummel, Laura Nied
Physiological needs that are currently unfulfilled are known to affect human cognition and behavior. The present study investigates whether and how the temporary activation of two primary physiological needs, namely hunger and sexual arousal, influence both the frequency and the contents of mind-wandering episodes. To induce hunger, one group of participants fasted for a minimum of five hours whereas another group of participants was exposed to audio material with explicit sexual content to provoke sexual arousal...
October 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/28827423/on-the-effective-stress-law-for-rock-on-rock-frictional-sliding-and-fault-slip-triggered-by-means-of-fluid-injection
#15
Ernest Rutter, Abigail Hackston
Fluid injection into rocks is increasingly used for energy extraction and for fluid wastes disposal, and can trigger/induce small- to medium-scale seismicity. Fluctuations in pore fluid pressure may also be associated with natural seismicity. The energy release in anthropogenically induced seismicity is sensitive to amount and pressure of fluid injected, through the way that seismic moment release is related to slipped area, and is strongly affected by the hydraulic conductance of the faulted rock mass. Bearing in mind the scaling issues that apply, fluid injection-driven fault motion can be studied on laboratory-sized samples...
September 28, 2017: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/28821228/sg-adviser-mtdna-a-web-server-for-mitochondrial-dna-annotation-with-data-from-200-samples-of-a-healthy-aging-cohort
#16
Manuel Rueda, Ali Torkamani
BACKGROUND: Whole genome and exome sequencing usually include reads containing mitochondrial DNA (mtDNA). Yet, state-of-the-art pipelines and services for human nuclear genome variant calling and annotation do not handle mitochondrial genome data appropriately. As a consequence, any researcher desiring to add mtDNA variant analysis to their investigations is forced to explore the literature for mtDNA pipelines, evaluate them, and implement their own instance of the desired tool. This task is far from trivial, and can be prohibitive for non-bioinformaticians...
August 18, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28793781/second-line-antiretroviral-therapy-in-sub-saharan-africa-it-is-time-to-mind-the-gaps
#17
Richard A Murphy, Richard Court, Gary Maartens, Henry Sunpath
The delay between first-line antiretroviral therapy (ART) failure and initiation of second-line ART in resource-limited settings can be prolonged. Increasing evidence links delayed antiretroviral switch with increased risk for opportunistic infection (OI) and death, particularly in patients with advanced HIV at the time of first-line failure. As access to viral load (VL) monitoring widens beyond a few countries, mechanisms are needed to optimize the use of routine virologic monitoring and assure that first-line regimen failure results in prompt second-line switch...
December 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28757907/mind-your-crossings-mining-gis-imagery-for-crosswalk-localization
#18
Dragan Ahmetovic, Roberto Manduchi, James M Coughlan, Sergio Mascetti
For blind travelers, finding crosswalks and remaining within their borders while traversing them is a crucial part of any trip involving street crossings. While standard Orientation & Mobility (O&M) techniques allow blind travelers to safely negotiate street crossings, additional information about crosswalks and other important features at intersections would be helpful in many situations, resulting in greater safety and/or comfort during independent travel. For instance, in planning a trip a blind pedestrian may wish to be informed of the presence of all marked crossings near a desired route...
April 2017: ACM Transactions on Accessible Computing
https://www.readbyqxmd.com/read/28721513/does-pyuria-always-suggest-urinary-tract-infection-with-common-microorganisms-questions
#19
Mehmet Taşdemir, Hüseyin Kaya, Zeynep Atam Taşdemir
Genitourinary system tuberculosis (GUTB) is a chronic granulomatous infection in which tuberculous bacilli affect one or more organs in the genitourinary system. In this report, an unusual presentation of miliary tuberculosis was presented as GUTB. A 15-year-old girl presented with complaints of severe abdominal pain and dysuria. Abdominal examination showed tenderness and defense. Pyuria and microscopic hematuria were observed. Acute abdominal causes could not be excluded through abdominal ultrasound. On abdominal computed tomography, a necrotic lesion was detected in the right kidney...
July 18, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28717920/mother-and-adolescent-eating-in-the-context-of-food-insecurity-findings-from-urban-public-housing
#20
Meg Bruening, Joanna Lucio, Stephanie Brennhofer
Introduction Anecdotal evidence suggests that parents protect their children from food insecurity and its effects, but few studies have concurrently assessed food insecurity among youth and parents. The purpose of this study was to examine food insecurity and eating behaviors among an urban sample of mother-adolescent dyads. Methods Mother-adolescent dyads (n = 55) were from six public housing sites in Phoenix, Arizona who completed surveys during 2014. Multivariate mixed linear and logistic regression models assessed the relationship between mother and adolescent eating behaviors in the context of food insecurity...
October 2017: Maternal and Child Health Journal
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