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https://www.readbyqxmd.com/read/29159858/non-linear-effect-of-irradiance-on-photoheterotrophic-activity-and-growth-of-the-aerobic-anoxygenic-phototrophic-bacterium-dinoroseobacter-shibae
#1
Kasia Piwosz, David Kaftan, Jason Dean, Jiří Šetlík, Michal Koblížek
Aerobic Anoxygenic Photosynthetic (AAP) bacteria are an important component of marine microbial communities. They produce energy in light using bacteriochlorophyll a containing photosystems. This extra energy provides an advantage over purely heterotrophic bacteria. One of the most intensively studied AAP bacteria is Dinoroseobacter shibae, a member of the environmentally important Roseobacter clade. Light stimulates its growth and metabolism, but the effect of light intensity remains unclear. Here, we show that an increase in biomass along an irradiance gradient followed the exponential rise to the maximum curve, with saturation at about 300 µmol photons m(-2) s(-1) , without any inhibition at light intensities up to 600 µmol photons m(-2) s(-1) ...
November 21, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/29156255/competitive-adsorption-of-ppcp-and-humic-substances-by-carbon-nanotube-membranes-effects-of-coagulation-and-ppcp-properties
#2
Yifei Wang, Qing Yang, Junqing Dong, Haiou Huang
Natural organic matter (NOM) and pharmaceuticals and personal care products (PPCP) are known to compete for adsorption sites on carbon nanotubes (CNT), resulting in decreasing PPCP adsorption onto CNT. In this study, four types of PPCP, as such acetaminophen (AAP), caffeine (CAF), triclosan (TCS), and carbendazim (CBD) were used to investigate the effects of PPCP properties and NOM coagulation on the competitive adsorption of PPCP and NOM. Coagulation preferentially removed HS from a natural surface water, thereby increasing adsorption of AAP, CAF, TCS and CBD by 19%, 13%, 17% and 11%, respectively...
November 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29149994/a-novel-fluorescence-biosensor-for-sensitivity-detection-of-tyrosinase-and-acid-phosphatase-based-on-nitrogen-doped-graphene-quantum-dots
#3
Zhengyi Qu, Weidan Na, Xiaotong Liu, Hua Liu, Xingguang Su
In this paper, we developed a sensitive fluorescence biosensor for tyrosinase (TYR) and acid phosphatase (ACP) activity detection based on nitrogen-doped graphene quantum dots (N-GQDs). Tyrosine could be catalyzed by TYR to generate dopaquinone, which could efficiently quench the fluorescence of N-GQDs, and the degree of fluorescence quenching of N-GQDs was proportional to the concentration of TYR. In the presence of ACP, l-Ascorbic acid-2-phosphate (AAP) was hydrolyzed to generate ascorbic acid (AA), and dopaquinone was reduced to l-dopa, resulting in the fluorescence recovery of the quenched fluorescence by dopaquinone...
January 2, 2018: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29143501/-the-place-of-balloon-pulmonary-angioplasty-in-the-management-of-chronic-thromboembolic-pulmonary-hypertension
#4
Aileen Kharat, Béatrice Duxbury, Anne-Lise Hachull, Stéphane Noble, Hélène Bouvaist, Paola M Soccal, Frédéric Lador
Chronic thromboembolic pulmonary hypertension (CTEPH) is uncommon. Its diagnosis should not be delayed as its prognosis is poor if not treated. In most cases, an acute pulmonary embolism is found in the medical history of the patient. Once suspected, a specific work-up should be performed in a pulmonary hypertension (PH) center. The ventilation/perfusion scan has a central role in this workup but the emergence of non invasive imaging technologies provides morphological and functional information which take part in the therapeutic decision making, such as operability...
November 15, 2017: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29132812/the-antitumor-effect-of-folic-acid-conjugated-auricularia-auricular-polysaccharide-cisplatin-complex-on-cervical-carcinoma-cells-in-nude-mice
#5
Junqiang Qiu, Hua Zhang, Zhenyu Wang, Didi Liu, Shumin Liu, Wei Han, Joe M Regenstein, Lin Geng
A tumor-targeted, folic acid (FA) conjugated-Auricularia auricular polysaccharide (AAP) -cis-diaminedichloroplatinum (CDDP) complex (FA-AAP-CDDP) was used for cervical carcinoma chemotherapy. The drug delivery system was able to enhance the antitumor potency of CDDP, and to reduce the toxic side effects of CDDP. The kidney of mice treated by FA-AAP-CDDP complex had higher superoxide dismutase, catalase, and glutathione peroxidase activities, and lower malondialdehyde. FA-AAP-CDDP complex could induce more interleukin-2, interleukin-4, and interferon-γ in mice...
November 10, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29129740/survey-on-neonatal-end-of-life-comfort-care-guidelines-across-america
#6
Shelly Haug, Sara Farooqi, Christopher G Wilson, Andrew Hopper, Grace Oei, Brian Carter
CONTEXT: Infants of age < 1 year have the highest mortality rate in pediatrics. The American Academy of Pediatrics (AAP) published guidelines for palliative care in 2013, however, significant variation persists among local protocols addressing neonatal comfort care at the end-of-life (EOL). OBJECTIVES: The purpose of this study was to evaluate current neonatal EOL comfort care practices and clinician satisfaction across America METHODS: After Institutional Review Board approval (516005), an anonymous, electronic survey was sent to members of the AAP Section on Neonatal-Perinatal Medicine...
November 9, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29127365/the-primary-cilium-is-necessary-for-the-differentiation-and-the-maintenance-of-human-adipose-progenitors-into-myofibroblasts
#7
N Arrighi, K Lypovetska, C Moratal, S Giorgetti-Peraldi, C A Dechesne, C Dani, P Peraldi
The primary cilium is an organelle, present at the cell surface, with various biological functions. We, and others, have shown that it plays a role in the differentiation of adipose progenitors (APs) into adipocytes. APs can also differentiate into myofibroblasts when treated with TGF-β1. Several components of the TGF-β1 pathway are located within the cilium suggesting a function for this organelle in AP myofibrogenesis. We studied differentiation of APs into myofibroblasts in two human models: APs of the adipose tissue (aAPs) and APs resident in the skeletal muscles (mAPs)...
November 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29113971/correction-to-2017-acc-aap-aha-health-policy-statement-on-opportunities-and-challenges-in-pediatric-drug-development-learning-from-sildenafil
#8
(no author information available yet)
No abstract text is available yet for this article.
November 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/29112088/serum-25-hydroxy-vitamin-d-levels-in-very-low-birth-weight-infants-receiving-oral-vitamin-d-supplementation
#9
Upender K Munshi, Pauline D Graziano, Kara Meunier, Jennifer Ludke, Angel Rios
BACKGROUND: Vitamin D supplementation in preterm infants has been recommended by American Academy of Pediatrics (AAP) however its efficacy and safety has not been well studied. OBJECTIVE: To study 25 hydroxy vitamin D (25OHD) levels as a marker of vitamin D status of very low birth weight infants while on vitamin D supplementation during NICU hospitalization. METHODS: Retrospective study of preterm infants with birth weight <1500 g admitted to our unit from Jan 2013 to Dec 2015 who were on oral Vitamin D3 400 IU supplementation...
November 3, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29111941/reasons-to-amplify-the-role-of-parental-permission-in-pediatric-treatment
#10
Mark Christopher Navin, Jason Adam Wasserman
Two new documents from the Committee on Bioethics of the American Academy of Pediatrics (AAP) expand the terrain for parental decision making, suggesting that pediatricians may override only those parental requests that cross a harm threshold. These new documents introduce a broader set of considerations in favor of parental authority in pediatric care than previous AAP documents have embraced. While we find this to be a positive move, we argue that the 2016 AAP positions actually understate the importance of informed and voluntary parental involvement in pediatric decision making...
November 2017: American Journal of Bioethics: AJOB
https://www.readbyqxmd.com/read/29097602/prevalence-of-dental-disorders-in-degus-and-evaluation-of-diagnostic-methods-to-determine-dental-disease-and-its-prognosis
#11
Hester van Bolhuis, Lotte van Hoffen, Martine van Zijll Langhout, Heleen van Engeldorp Gastelaars, Wouter Hendriks, Marnix Lamberts, Marja Kik
Degus (Octodon degus) are prone to develop dental disease with deleterious health effects. The two studies reported here aimed to determine the prevalence of dental disorders in degus and to identify and evaluate diagnostic tools for determination of prognosis of these disorders. In study A, health data from 225 degus at AAP, Rescue Center for Exotic Animals in the Netherlands, were collated and the prevalence of dental disorders and differences in sex and age at clinical onset of symptoms associated with dental disorders were described...
November 2, 2017: Veterinary Record
https://www.readbyqxmd.com/read/29091978/sustainability-in-the-aap-bronchiolitis-quality-improvement-project
#12
Kristin A Shadman, Shawn L Ralston, Matthew D Garber, Jens Eickhoff, Grant M Mussman, Susan C Walley, Elizabeth Rice-Conboy, Ryan J Coller
BACKGROUND AND OBJECTIVES: Adherence to American Academy of Pediatrics (AAP) bronchiolitis clinical practice guideline recommendations improved significantly through the AAP's multiinstitutional collaborative, the Bronchiolitis Quality Improvement Project (BQIP). We assessed sustainability of improvements at participating institutions for 1 year following completion of the collaborative. METHODS: Twenty-one multidisciplinary hospital-based teams provided monthly data for key inpatient bronchiolitis measures during baseline and intervention bronchiolitis seasons...
November 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29077700/electroencephalographic-indicators-in-default-mode-habituation-and-visual-motor-association-in-female-college-students
#13
Héctor Brust-Carmona, Yessica Martínez-Serrato, Ana Sánchez-Quezada, Blanca Flores-Avalos, Javier Alducin-Castillo, Oscar Yáñez-Suarez
BACKGROUND: Oscillations, action, and postsynaptic potentials in glial-neuronal ensembles integrate the spectral power (SP) of electroencephalographic (EEG). Our objective is to propose SP indicators of healthy brains (control groups) based on the default mode and their modifications by habituation and visual-motor association (VM-asso), to support diagnostic and rehabilitation processes. However, important differences seem to exist between men and women. Therefore, we aim to analyze EEG characteristics in a female sample...
September 2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
https://www.readbyqxmd.com/read/29058568/retention-and-use-of-newborn-resuscitation-skills-following-a-series-of-helping-babies-breathe-trainings-for-midwives-in-rural-ghana
#14
Darren Eblovi, Patricia Kelly, Georgina Afua, Sarah Agyapong, Siddhartha Dante, Matthew Pellerite
BACKGROUND: The Helping Babies Breathe (HBB) program teaches basic newborn resuscitation techniques to birth attendants in low-resource settings. Previous studies have demonstrated a decrease in mortality following training, mostly in large hospitals. However, low-volume clinics in rural regions with no physician immediately available likely experience a greater relative burden of newborn mortality. This study aimed to determine the impact of HBB trainings provided to rural Ghanaian midwives on their skills retention and on first 24 hour mortality of the newborns they serve...
2017: Global Health Action
https://www.readbyqxmd.com/read/29057817/unresolved-issues-for-utilization-of-atypical-antipsychotics-in-schizophrenia-antipsychotic-polypharmacy-and-metabolic-syndrome
#15
REVIEW
Sang Won Jeon, Yong-Ku Kim
Atypical antipsychotics (AAP) are the prevailing form of schizophrenia treatment today due to their low side effects and superior efficacy. Nevertheless, some issues still need to be addressed. First, there are still a large number of patients with treatment-resistant schizophrenia (TRS), which has led to a growing trend to resort to AAP polypharmacy with few side effects. Most clinical treatment guidelines recommend clozapine monotherapy in TRS, but around one third of schizophrenic patients fail to respond to clozapine...
October 18, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29056300/screening-children-at-risk-for-retinoblastoma-consensus-report-from-the-american-association-of-ophthalmic-oncologists-and-pathologists
#16
Alison H Skalet, Dan S Gombos, Brenda L Gallie, Jonathan W Kim, Carol L Shields, Brian P Marr, Sharon E Plon, Patricia Chévez-Barrios
PURPOSE: To provide a set of surveillance guidelines for children at risk for development of retinoblastoma. DESIGN: Consensus panel. PARTICIPANTS: Expert panel of ophthalmic oncologists, pathologists, and geneticists. METHODS: A group of members of the American Association of Ophthalmic Oncologists and Pathologists (AAOOP) with support of the American Association for Pediatric Ophthalmology and Strabismus and the American Academy of Pediatrics (AAP) was convened...
October 18, 2017: Ophthalmology
https://www.readbyqxmd.com/read/29035421/updated-guideline-may-improve-the-recognition-and-diagnosis-of-hypertension-in-children-and-adolescents-review-of-the-2017-aap-blood-pressure-clinical-practice-guideline
#17
REVIEW
Janis M Dionne
PURPOSE OF REVIEW: Hypertension in children and adolescents is under-recognized and under-diagnosed in clinical practice. The 2017 AAP Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents provides updated recommendations that may improve hypertension identification and management. RECENT FINDINGS: The AAP blood pressure guideline recommends annual screening for hypertension in children at preventive care visits and targeted routine screening in high-risk populations...
October 16, 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/28990427/chew-on-this-not-all-first-finger-foods-are-created-equal
#18
Nicol Awadalla, Tammy Pham, Ruth Milanaik
The American Academy of Pediatrics (AAP) recommends when to start first finger foods (FFFs) and what types of foods to start with, but it is unclear whether products marketed as FFF comply with these recommendations. We evaluated FFF products for compliance with AAP recommendations and product safety using 41 adult product testers, who were asked to dissolve each product in their mouth. Product characteristics, comments pertaining to product safety, and time to dissolve each product were recorded. Only 2 products met all AAP criteria, and safety concerns were raised for an additional 2 products...
October 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28988296/pivotal-factors-for-successful-withdrawal-of-nonsteroidal-anti-inflammatory-drugs-in-rheumatoid-arthritis-patients-in-remission-or-with-low-disease-activity
#19
Dong Jin Go, Kichul Shin, Han Joo Baek, Seong Wook Kang, Young Mo Kang, Jae Bum Jun, Yun Jong Lee, Sung Hwan Park, Yeong Wook Song
The purpose of this study is to examine the patient-reported outcomes (PRO) after discontinuing nonsteroidal anti-inflammatory drugs (NSAIDs) and clinical factors associated with a favorable outcome in patients with rheumatoid arthritis (RA) in remission or with low-disease activity (LDA). A 16-week prospective open-label trial was conducted at eight rheumatology clinics in Korea. RA patients with 28-joint disease activity score based on erythrocyte sedimentation rate (DAS28-ESR) < 3.2 who were on NSAIDs for more than a month were enrolled, and NSAIDs were discontinued...
October 8, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28986090/urinary-tract-infection-in-children-diagnosis-treatment-imaging-comparison-of-current-guidelines
#20
REVIEW
M Okarska-Napierała, A Wasilewska, E Kuchar
BACKGROUND AND OBJECTIVE: Urinary tract infection (UTI) is a frequent disorder of childhood, yet the proper approach for a child with UTI is still a matter of controversy. The objective of this study was to critically compare current guidelines for the diagnosis and management of UTI in children, in light of new scientific data. METHODS: An analysis was performed of the guidelines from: American Academy of Pediatrics (AAP), National Institute for Health and Care Excellence (NICE), Italian Society of Pediatric Nephrology, Canadian Paediatric Society (CPS), Polish Society of Pediatric Nephrology, and European Association of Urology (EAU)/European Society for Pediatric Urology (ESPU)...
September 19, 2017: Journal of Pediatric Urology
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