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https://www.readbyqxmd.com/read/28454195/-unicompartmental-vs-total-knee-arthroplasty-for-medial-osteoarthritis
#1
Tilman Pfitzner, Carsten Perka, Philipp von Roth
Background In end-stage medial osteoarthritis, the surgeon can decide whether to use unicompartmental or total knee arthroplasty for operative treatment of the patient. Despite the available literature there is a lack of evidence to suggest if one procedure can be rated as being superior to the other. With increasing demand for knee arthroplasty, treatment with the highest expectation of success will be of particular interest. The purpose of this manuscript was to analyse and compare the available literature on unicompartmental vs...
April 28, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28447122/an-overview-of-the-role-of-lipid-peroxidation-derived-4-hydroxynonenal-in-osteoarthritis
#2
REVIEW
Jamilah Abusarah, Mireille Bentz, Houda Benabdoune, Patricia Elsa Rondon, Qin Shi, Julio C Fernandes, Hassan Fahmi, Mohamed Benderdour
BACKGROUND: Over the years, many theories have been proposed and examined to better explain the etiology and development of osteoarthritis (OA). The characteristics of joint destruction are one of the most important aspects in disease progression. Therefore, investigating different factors and signaling pathways involved in the alteration of extracellular matrix (ECM) turnover, and the subsequent catabolic damage to cartilage holds chief importance in understanding OA development. Among these factors, reactive oxygen species (ROS) have been at the forefront of the physiological and pathophysiological OA investigation...
April 26, 2017: Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.]
https://www.readbyqxmd.com/read/28445369/a-systematic-review-of-different-implants-and-approaches-for-proximal-interphalangeal-joint-arthroplasty
#3
Michiro Yamamoto, Sunitha Malay, Yuki Fujihara, Lin Zhong, Kevin C Chung
BACKGROUND: Outcomes after implant arthroplasty for primary degenerative and posttraumatic osteoarthritis of the proximal interphalangeal joint were different according to the implant design and surgical approach. The purpose of this systematic review was to evaluate outcomes of various types of implant arthroplasty for proximal interphalangeal joint osteoarthritis, with an emphasis on different surgical approaches. METHODS: The authors searched all available literature in the PubMed and EMBASE databases for articles reporting on outcomes of implant arthroplasty for proximal interphalangeal joint osteoarthritis...
May 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28444338/aquatic-exercise-for-the-treatment-of-hip-and-knee-osteoarthritis
#4
Marcia R Franco, Priscilla K Morelhão, Augusto Cesinando, Rafael Z Pinto
Highlights the findings and application of Cochrane reviews and other evidence pertinent to the practice of physical therapy. The Cochrane library is a respected source of reliable evidence related to health care. Cochrane systematic reviews explore the evidence for and against the effectiveness and appropriateness of interventions-medications, surgery, education, nutrition, exercise-and the evidence for and against the use of diagnostic tests for specific conditions. Cochrane reviews are designed to facilitate the decisions of clinicians, patients, and others in health care by providing a careful review and interpretation of research studies published in the scientific literature...
April 21, 2017: Physical Therapy
https://www.readbyqxmd.com/read/28441721/pathogenic-or-therapeutic-extracellular-vesicles-in-rheumatic-diseases-role-of-mesenchymal-stem-cell-derived-vesicles
#5
REVIEW
Stella Cosenza, Maxime Ruiz, Marie Maumus, Christian Jorgensen, Danièle Noël
Extracellular vesicles (EVs) are important mediators of cell-to-cell communication pathways via the transport of proteins, mRNA, miRNA and lipids. There are three main types of EVs, exosomes, microparticles and apoptotic bodies, which are classified according to their size and biogenesis. EVs are secreted by all cell types and their function reproduces that of the parental cell. They are involved in many biological processes that regulate tissue homeostasis and physiopathology of diseases. In rheumatic diseases, namely osteoarthritis (OA) and rheumatoid arthritis (RA), EVs have been isolated from synovial fluid and shown to play pathogenic roles contributing to progression of both diseases...
April 22, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28441116/nerve-growth-factor-and-pain-mechanisms
#6
Franziska Denk, David L Bennett, Stephen B McMahon
Nerve growth factor (NGF) antagonism is on the verge of becoming a powerful analgesic treatment for numerous conditions, including osteoarthritis and lower back pain. This review summarizes the historical research, both fundamental and clinical, that led to our current understanding of NGF biology. We also discuss the surprising number of questions that remain about NGF expression patterns and NGF's various functions and interaction partners in relation to persistent pain and the potential side effects of anti-NGF therapy...
April 24, 2017: Annual Review of Neuroscience
https://www.readbyqxmd.com/read/28438380/the-role-of-muscle-strengthening-in-exercise-therapy-for-knee-osteoarthritis-a-systematic-review-and-meta-regression-analysis-of-randomized-trials
#7
REVIEW
Cecilie Bartholdy, Carsten Juhl, Robin Christensen, Hans Lund, Weiya Zhang, Marius Henriksen
OBJECTIVES: To analyze if exercise interventions for patients with knee osteoarthritis (OA) following the American College of Sports Medicine (ACSM) definition of muscle strength training differs from other types of exercise, and to analyze associations between changes in muscle strength, pain, and disability. METHODS: A systematic search in 5 electronic databases was performed to identify randomized controlled trials comparing exercise interventions with no intervention in knee OA, and reporting changes in muscle strength and in pain or disability assessed as standardized mean differences (SMD) with 95% confidence intervals (95% CI)...
March 18, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28438185/comparison-of-the-efficacy-between-conventional-moxibustion-and-smoke-free-moxibustion-on-knee-osteoarthritis-study-protocol-of-a-randomized-controlled-trial
#8
Lin-Lin Zhu, Jian-Ying Zhou, Ling Luo, Xiang Wang, Jia-Xi Peng, Sha-Sha Chen, Hai-Yan Yin, Qiao-Feng Wu, Cheng-Shun Zhang, Peng Lv, Yong Tang, Shu-Guang Yu
BACKGROUND: Conventional moxibustion is a representative non-drug intervention in traditional Chinese medicine, and it has been reported to produce encouraging results and benefits in relieving symptoms and improving the quality of life for patients with knee osteoarthritis (KOA) in previous clinical trials and systematic reviews. Given that increasing concerns on the safety of generated smoke from conventional moxibustion have received much attention, smoke-free moxibustion is regarded as a potential alternative...
April 24, 2017: Trials
https://www.readbyqxmd.com/read/28437503/subscapularis-tenotomy-versus-lesser-tuberosity-osteotomy-for-total-shoulder-arthroplasty-a-systematic-review
#9
Philip K Louie, David M Levy, Bernard R Bach, Gregory P Nicholson, Anthony A Romeo
Subscapularis tenotomy (ST) has been the standard method of mobilizing the subscapularis during the approach to a total shoulder arthroplasty (TSA). Recently, lesser tuberosity osteotomy (LTO), which avoids subscapularis complications, has gained in popularity. We performed a systematic review to elucidate any differences in clinical or radiographic outcomes between ST and LTO. Using PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, we identified clinical and/or radiographic TSA studies with minimum mean 2-year follow-up and level I to IV evidence...
March 2017: American Journal of Orthopedics
https://www.readbyqxmd.com/read/28436583/physical-activity-and-exercise-for-chronic-pain-in-adults-an-overview-of-cochrane-reviews
#10
REVIEW
Louise J Geneen, R Andrew Moore, Clare Clarke, Denis Martin, Lesley A Colvin, Blair H Smith
BACKGROUND: Chronic pain is defined as pain lasting beyond normal tissue healing time, generally taken to be 12 weeks. It contributes to disability, anxiety, depression, sleep disturbances, poor quality of life, and healthcare costs. Chronic pain has a weighted mean prevalence in adults of 20%.For many years, the treatment choice for chronic pain included recommendations for rest and inactivity. However, exercise may have specific benefits in reducing the severity of chronic pain, as well as more general benefits associated with improved overall physical and mental health, and physical functioning...
April 24, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28436377/analysis-of-therapeutic-effectiveness-of-selected-types-of-collagen-in-prevention-and-treatment-of-degenerative-joint-disease
#11
Wiesław Tomaszewski, Anna Paradowska
Loss of collagen is a natural development accompanying aging of the body. It may be additionally accelerated by various conditions, including osteoarthritis (OA). Within the last two decades numerous and diverse studies have been conducted worldwide with the aim of identifying substances containing collagen, producing therapeutic preparations of expected effectiveness in the prevention and therapy of OA that would be safe to use and developing methods of delivering the final product into the body. The authors reviewed and analysed the latest available literature by selecting papers presenting the findings of studies conducted in line with the principles of Evidence-Based Medicine (EBM)...
January 26, 2017: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28435570/outcome-of-treatment-of-osteoarthritis-with-arthroscopic-debridement-and-autologous-conditioned-plasma
#12
Ckk King, A Yung
INTRODUCTION: Worldwide estimates are that 9.6% of men and 18.0% of women aged over 60 years have symptomatic osteoarthritis. The current treatment options vary from conservative to joint replacement. Recently, debridement of the joint has become an option for symptomatic relief. We evaluated the outcome of arthroscopic debridement with autologous conditioned plasma. The latter helps to promote cellular repair. We have evaluated our results over a two year period. MATERIALS AND METHODS: We retrospectively analyzed a cohort of 52 patients who underwent arthroscopic knee debridement with autologous conditioned plasma in 2011...
March 2017: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/28435559/intra-articular-hyaluronic-acid-ha-and-platelet-rich-plasma-prp-injection-versus-hyaluronic-acid-ha-injection-alone-in-patients-with-grade-iii-and-iv-knee-osteoarthritis-oa-a-retrospective-study-on-functional-outcome
#13
C Saturveithan, G Premganesh, S Fakhrizzaki, M Mahathir, K Karuna, K Rauf, H William, H Akmal, N Sivapathasundaram, K Jaspreet
Introduction: Intra-articular hyaluronic acid (HA) is widely utilized in the treatment of knee osteoarthritis whereas platelet rich plasma (PRP) enhances the regeneration of articular cartilage. This study analyses the efficacy of HA and PRP in grade III and IV knee osteoarthritis. Methodology: This is a cross sectional study with retrospective review of 64 patients (101 knees) which includes 56 knees injected with HA+ PRP, and 45 knees with HA only. Results: During the post six months International Knee Documentation Committee (IKDC) evaluation, HA+PRP group showed marked improvement of 24...
July 2016: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/28435336/anterior-cruciate-ligament-injury-reinjury-in-alpine-ski-racing-a-narrative-review
#14
REVIEW
Matthew J Jordan, Per Aagaard, Walter Herzog
The purpose of the present review was to: 1) provide an overview of the current understanding on the epidemiology, etiology, risk factors, and prevention methods for anterior cruciate ligament (ACL) injury in alpine ski racing; and 2) provide an overview of what is known pertaining to ACL reinjury and return to sport after ACL injury in alpine ski racing. Given that most of the scientific studies on ACL injuries in alpine ski racing have been descriptive, and that very few studies contributed higher level scientific evidence, a nonsystematic narrative review was employed...
2017: Open Access Journal of Sports Medicine
https://www.readbyqxmd.com/read/28432457/outcome-and-revision-rate-of-uncemented-glenohumeral-resurfacing-c-a-p-after-5-8%C3%A2-years
#15
P C Geervliet, M P J van den Bekerom, P Spruyt, M Curvers, A van Noort, C P J Visser
BACKGROUND: Resurfacing of the glenohumeral joint for patients with glenohumeral arthritis has gained popularity since the first introduction. We report the mid-term results of the Global C.A.P. uncemented resurfacing shoulder prosthesis (DePuy Synthes). METHODS: From January 2007 to December 2009, 48 humeral cementless resurfacing prostheses in 46 patients were performed. All patients were diagnosed with primary glenohumeral osteoarthritis. Patients were contacted for review; the Constant Score, visual analog pain scale, Dutch Simple Shoulder Test, SF-12 scores and physical examination were assessed both preoperatively and yearly postoperatively...
April 21, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28429337/from-acute-to-chronic-pain-tapentadol-in-the-progressive-stages-of-this-disease-entity
#16
F Coluzzi, D Fornasari, J Pergolizzi, P Romualdi
OBJECTIVE: Chronic pain is now recognized as a neural disease, which results from a maladaptive functional and structural transformation process occurring over time. In its chronic phase, pain is not just a symptom but also a disease entity. Therefore, pain must be properly addressed, as many patients still report unsatisfactory pain control despite on-going treatment. The selection of the therapy - taking into account the pathophysiological mechanisms of pain - and the right timing can result in a successful analgesic outcome...
April 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28428913/comparison-of-magnetic-resonance-imaging-and-radiographs-for-evaluation-of-carpal-osteoarthritis
#17
Angela E Li, Steve K Lee, Schneider K Rancy, Alissa J Burge, Hollis G Potter, Scott W Wolfe
Background We sought to evaluate the interobserver and intraobserver reliability of radiographs and magnetic resonance imaging (MRI) for grading of osteoarthritis in patients with scapholunate advanced collapse (SLAC) and scaphoid nonunion advanced collapse (SNAC), and to determine whether MRI is more likely than radiographs to detect carpal osteoarthritis. Methods Radiographs and MR studies of 46 patients with SLAC and SNAC arthritis were reviewed by two hand surgeons and two radiologists and were graded according to severity of osteoarthritis at seven carpal joints...
May 2017: Journal of Wrist Surgery
https://www.readbyqxmd.com/read/28428036/giantcell-tumor-of-tendon-sheath-open-surgery-or-arthroscopic-synovectomy-a-systematic-review-of-the-literature
#18
REVIEW
Thibaut Noailles, Kevin Brulefert, Sylvain Briand, Pierre Marie Longis, Kevin Andrieu, Antoine Chalopin, François Gouin
PURPOSE: Giantcell tumor of tendon sheath(GCTTS)formelyknowned as pigmented villonodular synovitis (PVNS) is a benign, locally aggressive, proliferative disorder of the synovium involving a joint, bursa, or tendon sheath. Treatment ofGCTTSinvolves early surgical resection to limit articular destruction and the risk of recurrence. Synovectomy remains the treatment of choice forGCTTSbut without clear consensus to make an open or arthroscopic synovectomy andno certainty on the responsibility of surgery in the evolution towards the degenerative osteoarthritis...
April 17, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28424692/t-cells-in-osteoarthritis-alterations-and-beyond
#19
REVIEW
Yu-Sheng Li, Wei Luo, Shou-An Zhu, Guang-Hua Lei
Although osteoarthritis (OA) has been traditionally regarded as a non-inflammatory disease, reports increasingly suggest that it is inflammatory, at least in certain patients. OA patients often exhibit inflammatory infiltration of synovial membranes by macrophages, T cells, mast cells, B cells, plasma cells, natural killer cells, dendritic cells, granulocytes, etc. Although previous reviews have summarized the knowledge of inflammation in the pathogenesis of OA, as far as we know, no report review our current understanding about T cells, especially, each T cell subtype, in the biology of OA...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28423287/microfracture-versus-autologous-chondrocyte-implantation-for-articular-cartilage-lesions-in-the-knee-a-systematic-review-of-5-year-outcomes
#20
Matthew J Kraeutler, John W Belk, Justin M Purcell, Eric C McCarty
BACKGROUND: Microfracture (MFx) and autologous chondrocyte implantation (ACI) are 2 surgical treatment options used to treat articular cartilage injuries of the knee joint. PURPOSE: To compare the midterm to long-term clinical outcomes of MFx versus ACI for focal chondral defects of the knee. STUDY DESIGN: Systematic review. METHODS: A systematic review was performed by searching PubMed, the Cochrane Library, and Embase to locate studies (level of evidence I-III) comparing the minimum average 5-year clinical outcomes of patients undergoing MFx versus ACI...
April 1, 2017: American Journal of Sports Medicine
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