Juan A Navarro, Caridad Díaz, Juan Decara, Dina Medina-Vera, Antonio J Lopez-Gambero, Juan Suarez, Francisco Javier Pavón, Antonia Serrano, Antonio Vargas, Ana Luisa Gavito, Oscar Porras-Perales, Jesús Aranda, Francisca Vicente, Carlos Sanjuan, Elena Baixeras, Fernando Rodríguez de Fonseca
The present study characterizes the oral pharmacokinetics of D-Pinitol, a natural insulin mimetic inositol, in human healthy volunteers (14 males and 11 females). D-Pinitol absorption was studied in (a) subjects receiving a single oral dose of 15 mg/kg ( n = 10), or (b) 5 mg/kg pure D-Pinitol ( n = 6), and (c) subjects receiving D-Pinitol as part of carbohydrate-containing carob pods-derived syrup with a 3.2% D-Pinitol (Dose of 1600 mg/subject, n = 9). The volunteers received a randomly assigned single dose of either D-Pinitol or carob pod-derived syrup...
October 1, 2022: Nutrients