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vitamin d deficiency in children

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https://www.readbyqxmd.com/read/28429909/association-between-maternal-vitamin-d-status-during-pregnancy-and-offspring-cognitive-function-during-childhood-and-adolescence
#1
Sargoor R Veena, Ghattu V Krishnaveni, Krishnamachari Srinivasan, Kotrangada P Thajna, Bhavya G Hegde, Catharine R Gale, Caroline Hd Fall
BACKGROUND AND OBJECTIVES: Animal studies have demonstrated poor cognitive outcomes in offspring in relation to maternal vitamin D deficiency before and/or during pregnancy. Human studies linking maternal vitamin D status during pregnancy with offspring cognitive function are limited. We aimed to test the hypothesis that lower maternal vitamin D status during pregnancy is associated with poor offspring cognitive ability in an Indian population. METHODS AND STUDY DESIGN: Cognitive function was assessed in children from the Mysore Parthenon birth cohort during childhood (age 9-10 years; n=468) and adolescence (age 13-14 years; n=472) using 3 core tests from the Kaufman Assessment Battery for children and additional tests measuring learning, long-term retrieval/ storage, short-term memory, reasoning, verbal fluency, visuo-spatial ability, and attention and concentration...
May 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28421785/association-between-vitamin-d-levels-and-cardiovascular-risk-factors-in-obese-children-and-adolescents
#2
Ali Gul, Samet Ozer, Resul Yılmaz, Ergun Sonmezgoz, Tuba Kasap, Sahin Takcı, Osman Demir
BACKGROUND AND AIM: Childhood obesity is associated with an increased risk of chronic disease. We aimed to determine the association between vitamin D deficiency and cardiovascular risks in obese children. METHOD: The studied children were selected from obese children who were followed up at obesity clinic, aged 6-17 years. Basic demographic information and laboratory data were collected retrospectively from hospital records. RESULTS: A total of 310 students (178 [57...
March 30, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28416062/-growing-pains-are-well-known-but-the-cause-remains-unclear
#3
Fie Brantbjerg Tinning, Lise Hestbæk, Anne-Marie Nybo Andersen
A common complaint from children is growing pains: a mild to severe pain located primarily in the legs and being most intense in evenings and during sleep. The diagnosis is based on the characteristics of the pain and careful clinical examination. The pain disappears as the child grows up. Research has suggested that the pain occurs more often in children who suffer from vitamin D deficiency, low bone density, low pain threshold, restless legs syndrome and in children who were breastfed for less than 40 days from birth...
April 17, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28403955/french-prenatal-vitamin-d-recommended-supplementation-enough-or-not
#4
P-F Ceccaldi, H Pejoan, N Breau, D Diallo, G Ducarme, O Poujade, C Davitian, D Luton
OBJECTIVE: To determine the impact of current recommended vitamin D prenatal supplementation on blood cord 25(OH)D level in a French cohort and to determine population at risk of higher needs. DESIGN AND SETTING: An observational prospective study was conducted in teaching hospital including two large groups of newborns, one born after summer and another after winter period. PATIENTS AND METHODS: Three hundred and ninety-nine mother/newborns pairs were enrolled and blood cord results were available for 225 newborns in the post-summer group and 174 newborns in the post-winter group...
January 2017: J Gynecol Obstet Hum Reprod
https://www.readbyqxmd.com/read/28401345/vitamin-d-in-european-children-statement-from-the-european-academy-of-paediatrics-eap
#5
Zachi Grossman, Adamos Hadjipanayis, Tom Stiris, Stefano Del Torso, Jean-Christophe Mercier, Arunas Valiulis, Raanan Shamir
Vitamin D is synthesized in human skin upon sun exposure and is also a nutrient. It regulates calcium and phosphate metabolism and is essential for the maintenance of bone health. Vitamin D supplementation during infancy, in order to prevent rickets, is universally accepted. Many human cell types carry vitamin D receptor, this being a drive for conducting studies on the possible association between vitamin D status and other diseases. Studies have affirmed that a considerable number of healthy European children may be vitamin D deficient, especially in high-risk groups (darker pigmented skin, living in areas with reduced sun exposure and other disorders)...
April 12, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28401055/effect-of-the-baseline-vitamin-d-level-on-growth-outcome-in-pediatric-crohn-disease
#6
Eun Joo Lee, Jin Soo Moon, Jae Sung Ko, Hye Ran Yang, Ju Young Jang, Ju Whi Kim, Kyung Jae Lee
PURPOSE: Vitamin D deficiency is common in Crohn disease (CD). The aim of the study was to examine the prevalence of vitamin D deficiency and evaluate the association between vitamin D status and growth outcome in Korean pediatric CD patients. METHODS: In this retrospective study, 17 children younger than 18 years old diagnosed with CD were enrolled and their serum 25-hydroxy vitamin D (25[OH]D) was checked between 2011 and 2015. We categorized the patients into two groups, Group 1 and Group 2...
March 2017: Pediatric Gastroenterology, Hepatology & Nutrition
https://www.readbyqxmd.com/read/28399423/bone-mineral-density-and-vitamin-d-concentration-the-challenges-in-taking-care-of-children-and-adolescents-infected-with-hiv
#7
Fabiana Bononi Carmo, Maria Teresa Terreri, Regina Célia de Menezes Succi, Suenia Vasconcelos Beltrão, Aida de Fátima Tomé Barbosa Gouvea, Erica Regina Cruz Paulino, Daisy Maria Machado
The increase in life expectancy for patients living with human immunodeficiency virus (HIV) infection has resulted in health complications related to a chronic disease. OBJECTIVES: To evaluate the prevalence of bone mineral density (BMD) alterations and vitamin D concentrations in HIV-infected children and adolescents and to verify the variations in those parameters during a 12-month interval. METHODS: A prospective cohort study with a dual period of evaluation was conducted in 57 patients perinatally HIV-infected and one patient with sexual abuse in early infancy...
April 8, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28389119/nutritional-status-among-adolescent-girls-in-children-s-homes-anthropometry-and-dietary-patterns
#8
Tone Berg, Christine Magala-Nyago, Per Ole Iversen
BACKGROUND & AIMS: Malnutrition is widespread among disadvantaged people in low-income countries like Uganda. Children and adolescents living in children's homes are considered an especially vulnerable group, and malnutrition among girls is of particular concern since it has intergenerational consequences. Virtually no information exists about the nutritional status of adolescent girls living in children's homes in Uganda. We therefore conducted a cross-sectional study to assess the nutritional status by evaluating anthropometric indicators, body composition and dietary patterns...
March 25, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28386818/potential-risk-factors-for-vitamin-d-levels-in-medium-and-long-term-use-of-antiepileptic-drugs-in-childhood
#9
Edibe Pempegül Yildiz, Şükran Poyrazoglu, Gonca Bektas, Aslı Derya Kardelen, Nur Aydinli
Antiepileptic drugs (AED) have potential side effects through vitamin-D. Prevalence of vitamin D insufficiency and potential risk factors for the longitudinal changes of vitamin D levels compared to its baseline levels under AED treatment were investigated in this study. This retrospective study includes patients whose AED therapy were started in only autumn months, between 2000 and 2014. Detailed assessment of neurologic diagnosis and brain MRI findings, ambulatory status, types and durations of AED treatment, and baseline bone health blood tests (vitamin-D, alkaline phosphatase, calcium, and phosphate levels) were obtained on all patients...
April 6, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/28381562/a-pilot-interventional-study-to-evaluate-the-impact-of-cholecalciferol-treatment-on-hba1c-in-type-1-diabetes
#10
Reena Perchard, Lucia Magee, Fiona Ivison, Andrew J Whatmore, Philip Murray, Adam Stevens, Sarah Ehtisham, Judith Campbell, Marie Marshall, Susan Ainsworth, Mark Bone, Ian Doughty, M Zulf Mughal, Peter E Clayton
BACKGROUND: Higher 25(OH)D3 levels are associated with lower Hba1c, but there are limited interventional trials assessing the effect of cholecalciferol on Hba1c. AIMS: (1) To assess baseline 25(OH)D3 status in a Manchester paediatric cohort of patients with T1D. (2) To determine the effect of cholecalciferol administration on Hba1c. METHODS: Children with T1D attending routine clinic appointments over three months in late winter/early spring had blood samples taken with consent, and patients with a 25(OH)D3 level <20ng/ml were treated with a one-off cholecalciferol dose of 100 000 (2-10 years) or 160 000 (>10 years) units...
April 5, 2017: Endocrine Connections
https://www.readbyqxmd.com/read/28381355/elevated-systolic-blood-pressure-of-children-in-the-united-states-is-associated-with-low-serum-25-hydroxyvitamin-d-concentrations-related-to-body-mass-index-national-health-and-examination-survey-2007-2010
#11
Carolyn E Moore, Yan Liu
A negative association between serum 25-hydroxyvitamn D (25[OH]D) concentrations and blood pressure has been found in adults; whether a similar relationship exists in children remains unclear. We hypothesized that serum 25(OH)D concentrations of children would negatively correlate with blood pressure. Using a nationally representative sample of children aged 8 to 18years from the National Health and Nutrition Examination Survey 2007-2010 (n=2908), we compared serum 25(OH)D levels with diastolic and systolic blood pressure by vitamin D nutritional status categories...
February 2017: Nutrition Research
https://www.readbyqxmd.com/read/28380009/impact-of-fortified-biscuits-on-micronutrient-deficiencies-among-primary-school-children-in-bangladesh
#12
Alayne M Adams, Rushdia Ahmed, A H M Mahbub Latif, Sabrina Rasheed, Sumon K Das, Enamul Hasib, Fahmida Dil Farzana, Farzana Ferdous, Shahnawaz Ahmed, Asg Faruque
BACKGROUND: Micronutrient deficiencies can compromise the development potential of school-aged children, and their later health and productivity as adults. School feeding and school-based fortification approaches have been utilized globally to redress nutritional deficiencies in this age group. OBJECTIVE: We explored the acceptability and micronutrient impact of a Bangladesh Government supported school-based micronutrient fortification program for children attending rural primary schools in 10 disadvantaged sub-districts...
2017: PloS One
https://www.readbyqxmd.com/read/28376768/long-term-effects-of-vitamin-d-supplementation-in-vitamin-d-deficient-obese-children-participating-in-an-integrated-weight-loss-programme-a-double-blind-placebo-controlled-study-rationale-for-the-study-design
#13
Agnieszka Szlagatys-Sidorkiewicz, Michał Brzeziński, Agnieszka Jankowska, Paulina Metelska, Magdalena Słomińska-Frączek, Piotr Socha
BACKGROUND: Obesity is associated not only with an array of metabolic disorders (e.g. insulin resistance, hiperinsulinemia, impaired tolerance of glucose, lipid disorders) but also skeletal and joint abnormalities. Recently, a pleiotropic role of vitamin D has been emphasized. Obese children frequently present with vitamin D deficiency, and greater fat mass is associated with lower serum concentration of this vitamin. Although some evidence suggests that weight loss may affect vitamin D status, this issue has not been studied extensively thus far...
April 4, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28368931/vitamin-d-and-tibiofemoral-joint-orientation-angles-in-children
#14
Nedal Alkhatib, Fadi Bouri, Abdelsalam Hegazy, Talal Ibrahim
Vitamin D is an important component in musculoskeletal development and function in children. The aim of our study was to investigate vitamin D levels and tibiofemoral joint orientation angles in children. We performed a retrospective review on a consecutive series of children presenting with lower limb complaints. The children underwent an assessment of serum vitamin D level and full-length standing lower limb anteroposterior radiographs, and were divided into normal and deficient vitamin D groups. Tibiofemoral angles (TFAs) [lateral distal femoral angle (LDFA); medial proximal tibial angle (MPTA)] were measured by three independent observers and compared between the groups...
March 31, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28367920/age-related-vitamin-d-deficiency-is-associated-with-the-immune-response-in-children-with-community-acquired-pneumonia
#15
Yun Huang, Li Fu, Ying Yang
To investigate vitamin D status in children with community-acquired pneumonia (CAP) and explore the association between vitamin D deficiency and the immune response in CAP children, 77 children with CAP were retrospectively analyzed. The baseline characteristics of patients were obtained from medical records. Based on the blood samples collected during diagnosis of CAP, the routine blood examination results and proportions of lymphocyte subsets were assessed. There were 71.4% (55/77) of patients with vitamin D deficiency among CAP children...
2017: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/28360493/vitamin-d-levels-among-pediatric-tuberculosis-patients-does-it-alter-following-antitubercular-treatment-a-prospective-study-in-19-children
#16
Anil Agarwal, Pradeep Kumar Dabla, Madhusudan Mishra, Anubrat Kumar, Abbas Shaharyar
OBJECTIVES: It is still unknown whether altered vitamin D levels observed with osteoarticular tuberculosis change during treatment in a child or modify the disease course. To find a possible answer to the above query, we investigated serial serum 25 hydroxy vitamin D concentrations in children suffering from osteoarticular tuberculosis treated with multidrug antitubercular drugs. METHODS: The prospective study enrolled 19 untreated immunocompetent children with an established diagnosis of osteoarticular tuberculosis...
January 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28341008/serum-vitamin-d-level-in-egyptian-children-with-familial-mediterranean-fever
#17
Hala M Lotfy, Huda Marzouk, Yomna Farag, Ahmed Salah, Heba Taher, Mohamed Nabih, Laila Rashed, Kamal El-Garf
BACKGROUND: The aim of the study is to measure plasma vitamin D levels in a group of Egyptian children with familial Mediterranean fever (FMF) compared to healthy children. METHODS: The study enrolled 52 children with FMF and 40 apparently healthy controls. Serum vitamin D level was measured by enzyme-linked immunosorbent assay. RESULTS: The mean serum vitamin D level was significantly lower in children with FMF than control group (12.3±3...
March 21, 2017: Immunology Letters
https://www.readbyqxmd.com/read/28335672/effect-of-severe-vitamin-d-deficiency-at-admission-on-shock-reversal-in-children-with-septic-shock
#18
Jhuma Sankar, Javed Ismail, Rashmi Das, Nishanth Dev, Anubhuti Chitkara, M Jeeva Sankar
OBJECTIVES: To evaluate the association of severe vitamin D deficiency with clinically important outcomes in children with septic shock. METHODS: We enrolled children ≤17 years with septic shock prospectively over a period of 6 months. We estimated 25-hydroxyvitamin D [25 (OH) D] levels at admission and 72 hours. Severe deficiency was defined as serum 25 (OH) <10 ng/mL. We performed univariate and multivariate analysis to evaluate association with clinically important outcomes...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/28333101/nutrient-status-of-vitamin-d-among-chinese-children
#19
Shuojia Wang, Guosong Shen, Shuying Jiang, Hongwei Xu, Minchao Li, Zhaopin Wang, Su Zhang, Yunxian Yu
BACKGROUND: Vitamin D deficiency is considered to be a public health problem. However, the nutrient status of vitamin D in Chinese children is unclear. The aim of this study was to describe the vitamin D status among children aged under 18 years in southeast China. METHODS: Children who visited the Huzhou Maternal and Child Care Hospital from January 2012 to August 2015 were included in this large cross-sectional study. Serum 25-hydroxyvitamin D (25(OH)D) concentrations were measured by electrochemiluminescence immunoassay...
March 23, 2017: Nutrients
https://www.readbyqxmd.com/read/28328529/evaluation-of-vitamin-d-prophylaxis-in-3-36-month-old-infants-and-children
#20
Alper Ozcan, Mustafa Kendirci, Meda Kondolot, Fatih Kardas, Leyla Akın
BACKGROUND: Vitamin D (VD) deficiency (VDD) is still a population-based health problem that affects people at different ages. The aim of this study was to evaluate VD prophylaxis for the prevention of VDD in (3-36)-month-old infants and children. METHODS: Infants and children aged between 3 and 36 months, with different etiologies, admitted to outpatient and inpatient clinics from October 2010 to October 2011 at the Children's Hospital of Erciyes University, were enrolled for the study...
March 22, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
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