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vitamin d deficiency in children

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https://www.readbyqxmd.com/read/29301185/a-lack-of-association-between-vitamin-d-binding-protein-and-25-hydroxyvitamin-d-concentrations-in-pediatric-type-1-diabetes-without-microalbuminuria
#1
Hwa Young Kim, Young Ah Lee, Hae Woon Jung, Min Jeoung Gu, Ji Young Kim, Gyung Min Lee, Jieun Lee, Ju Young Yoon, Sei Won Yang, Choong Ho Shin
PURPOSE: Vitamin D deficiency is reported to be more common in type 1 diabetes patients and might be associated with the increased urinary loss of vitamin D binding protein (VDBP) consequent to impaired 25-hydroxyvitamin D (25(OH)D) circulation. We aimed to evaluate the possible increased urinary loss of VDBP, a correlation between VDBP and circulating 25(OH)D level, and risk factors influencing low vitamin D level in pediatric type 1 diabetes patients without microalbuminuria. METHODS: This is a cross-sectional study of subjects who visited Seoul National University Children's Hospital between January and March 2013...
December 2017: Annals of Pediatric Endocrinology & Metabolism
https://www.readbyqxmd.com/read/29284239/the-potential-impact-of-the-hypovitaminosis-d-on-metabolic-complications-in-obese-adolescents-preliminary-results
#2
Malgorzata Wojcik, Dominika Janus, Anna Kalicka-Kasperczyk, Krystyna Sztefko, Jerzy B Starzyk
INTRODUCTION AND OBJECTIVE: Vitamin D deficiency is common in obesity; however, its contribution in the development of metabolic complications remains uncertain. The aim of the study was to examine the relationships between vitamin D status and metabolic complications. MATERIAL AND METHODS: The results of blood pressure measurements, biochemical tests and ultrasound of the liver were compared in both groups. The study was conducted at the Children's University Hospital in Krakow, Poland...
December 23, 2017: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/29282177/vitamin-d-deficiency-and-atopic-dermatitis-consider-disease-race-and-body-mass
#3
Kavita Darji, Courtney Tobin, Zachary T Bryan, Mathew Jansenn, Eric Armbrecht, Elaine Siegfried
Vitamin D deficiency causes rickets, but has been associated with various diseases, including atopic dermatitis (AD). This study analyzes serum vitamin D in pediatric medical center patients with AD and potential confounding factors. At Cardinal Glennon Children's Hospital, charts of 665 children with serum 25-hydroxyvitamin D levels taken between 2009 and 2013 were retrospectively reviewed. Defining vitamin D deficiency as <20 ng/mL, neither average 25-hydroxyvitamin D nor deficiency prevalence varied among disease groups, except for cystic fibrosis (CF), which demonstrated significantly higher average vitamin D and lower deficiency prevalence...
2017: Skinmed
https://www.readbyqxmd.com/read/29273135/complex-relationships-between-vitamin-d-and-allergic-sensitization-among-puerto-rican-2-year-old-children
#4
Srimathi Kannan, Matthew S Perzanowski, Harish B Ganguri, Dolores Acevedo-Garcia, Luis M Acosta, Molly Spatcher, Adnan Divjan, Ginger L Chew
BACKGROUND: In the United States, Puerto Ricans have a higher prevalence of asthma than other Latino ethnicities. Low vitamin D levels for children living in northern climates could be a factor. OBJECTIVE: To assess serum 25-hydroxyvitamin D [25(OH)D] distributions (a marker of vitamin D) and associations among vitamin D, allergic sensitization, early wheeze, and home/demographic factors. METHODS: Puerto Rican infants born in New York City, with a maternal history of atopy, were enrolled in a birth cohort...
January 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29273017/vitamin-d-levels-in-schoolchildren-a-cross-sectional-study-in-kuwait
#5
Khulood Othman Alyahya
BACKGROUND: Ongoing studies in the Middle East, particularly in the Arabian Gulf countries, have reported extremely low levels of serum vitamin D across age and gender. In Kuwait, vitamin D deficiency is prevalent in adolescent girls and in adult women. A number of risk factors have been reported, among which gender, age, and obesity are a few. Because adequate vitamin D status is necessary to promote bone mineral accrual in childhood, and because low vitamin D levels have been associated with a wide range of health problems, there is concern that growing children with low vitamin D may be at higher risk for developing diseases...
December 22, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/29262471/-correlation-between-serum-25-hydroxyvitamin-d-level-and-core-symptoms-of-autism-spectrum-disorder-in-children
#6
H Y Dong, B Wang, H H Li, L Shan, F Y Jia
Objective: To explore the relationship between serum 25-hydroxyvitamin D levels and core symptoms of autism spectrum disorder (ASD) in children. Method: In this cross-sectional study, ASD children 4 to 6 years of age who were diagnosed in Department of Developmental and Behavioral Pediatrics, First Hospital of Jilin university from January to May 2017 were assigned to ASD group, and children for routine growth and development assessment in Jilin province were assigned to control group. The two groups were well matched for age and sex, and none of them had received vitamin D supplementation...
December 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29249133/serum-25-hydroxyvitamin-d-levels-in-children-with-recurrent-wheezing-and-relation-to-the-phenotypes-and-frequency-of-wheezing
#7
M Dogru, L P Seren
Background. Recurrent wheezing may be related to various reasons. There is a lack of knowledge about the effect of vitamin D status in the children with recurrent wheezing. The aim of this study is to compare the level of vitamin D between recurrent wheezing children and healthy controls, and to investigate the relationship between vitamin D status and the clinical parameters of recurrent wheezing in preschool children. Methods. One hundred-ten children followed up in our hospital with recurrent wheezing were included in the study...
November 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29247784/efficacy-of-vitamin-d-interventional-strategies-in-saudi-children-and-adults
#8
REVIEW
Nasser M Al-Daghri, Sherif H Abd-Alrahman, Amaresh Panigrahy, Yousef Al-Saleh, Naji Aljohani, Omar S Al-Attas, Majed Alokail, Malak N K Khattak
Despite the amount of sunshine in Saudi Arabia, vitamin D (25(OH)D) deficiency is highly prevalent among Saudis. Several strategies are known to improve 25(OH)D status. The aim of this study was to evaluate the efficacy of different interventional strategies in improving 25(OH)D status in Saudi children and adults. This interventional study was undertaken among 593 out of 1152 Saudi subjects [530 students (aged 13-17 years) and 63 teachers (aged 26-46 years)] over a 6-month period from different secondary schools in Riyadh, Saudi Arabia...
December 13, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29247782/response-of-serum-25-oh-d-to-vitamin-d-and-calcium-supplementation-in-school-children-from-a-semi-rural-setting-in-india
#9
REVIEW
Rubina Mandlik, Anuradha Khadilkar, Neha Kajale, Veena Ekbote, Vivek Patwardhan, Sejal Mistry, Vaman Khadilkar, Shashi Chiplonkar
The objectives of this study were to: 1) Determine the impact of varying baseline serum 25OHD on increase in vitamin D concentrations after daily supplementation with vitamin D and calcium (1000 IU + 500 mg respectively) for six months in school-children from a semi-rural setting 2) Test the efficacy of daily vitamin D-calcium supplementation on improvement in serum vitamin D concentrations to ≥75 nmol/L. Data collected from 106 subjects (58 boys, 48 girls), aged 6-12 years, included anthropometric measures like height and weight, body composition analysis, three one-day dietary recalls and sunlight exposure (by questionnaire)...
December 13, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29246096/pediatric-onset-multiple-sclerosis-a-single-center-study
#10
Erin Yamamoto, Matthew Ginsberg, Mary Rensel, Manikum Moodley
Pediatric-onset multiple sclerosis (POMS), once thought to be rare, is now being diagnosed in increasing numbers in children. Despite improvements to diagnostic criteria, the diagnosis and management of POMS remains challenging. The aim of this study is to retrospectively describe a growing POMS patient population seen at a single center over a 13 year period. Epidemiologic, clinical, neuroimaging, laboratory features and therapeutic management and outcome data were collected and analyzed. These data support associations between MS and environmental triggers such as obesity and vitamin D deficiency...
January 2018: Journal of Child Neurology
https://www.readbyqxmd.com/read/29241119/bench-to-bedside-review-possible-role-of-vitamin-d-in-autism-spectrum-disorder
#11
REVIEW
Feiyong Jia, Ling Shan, Bing Wang, Honghua Li, Chunyue Miao, Zhida Xu, Ching-Po Lin, Khaled Saad
Autism spectrum disorder (ASD) is a group of dysfunctions in social interaction, communication, and behaviors. Studies have demonstrated that vitamin D deficiency during pregnancy and in individuals increased the risk of ASD. A genetic polymorphism study has pinpointed that genotype AA/A-allele of GC rs4588 in children is associated with ASD, which encodes the vitamin D binding protein. Translating the mentioned points into clinical practice, several clinical trials have demonstrated that vitamin D supplementation can improve the core symptoms in children with ASD...
December 6, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29240264/longitudinal-vitamin-d-deficiency-is-inversely-related-to-mite-sensitization-in-early-childhood
#12
Chih-Yung Chiu, Kuan-Wen Su, Ming-Han Tsai, Man-Chin Hua, Sui-Ling Liao, Shen-Hao Lai, Li-Chen Chen, Tsung-Chieh Yao, Kuo-Wei Yeh, Jing-Long Huang
BACKGROUND: There are few studies addressing the longitudinal analysis of vitamin D deficiency and its impact to the development of atopic diseases in early childhood. METHODS: We investigated 155 children who regularly followed up at our clinic for 5 years as subjects enrolled in a birth cohort study. The pattern of vitamin D levels from birth to 5 years of age was clustered using K-means method in R software. Absolute eosinophil count (AEC), total serum and specific immunoglobulin E antibodies against food (egg white, milk, and wheat) and inhalant allergens (D...
December 14, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/29238379/correlation-of-vitamin-d-status-and-orthodontic-induced-external-apical-root-resorption
#13
Azita Tehranchi, Azin Sadighnia, Farnaz Younessian, Amir H Abdi, Armin Shirvani
Background: Adequate Vitamin D is essential for dental and skeletal health in children and adult. The purpose of this study was to assess the correlation of serum Vitamin D level with external-induced apical root resorption (EARR) following fixed orthodontic treatment. Materials and Methods: In this cross-sectional study, the prevalence of Vitamin D deficiency (defined by25-hydroxyvitamin-D) was determined in 34 patients (23.5% male; age range 12-23 years; mean age 16...
November 2017: Dental Research Journal
https://www.readbyqxmd.com/read/29234503/study-protocol-for-a-phase-ii-dose-evaluation-randomized-controlled-trial-of-cholecalciferol-in-critically-ill-children-with-vitamin-d-deficiency-vitdal-picu-study
#14
Dayre McNally, Karin Amrein, Katharine O'Hearn, Dean Fergusson, Pavel Geier, Matt Henderson, Ali Khamessan, Margaret L Lawson, Lauralyn McIntyre, Stephanie Redpath, Hope A Weiler, Kusum Menon
Background: Clinical research has recently demonstrated that vitamin D deficiency (VDD) is highly prevalent in the pediatric intensive care unit (PICU) and associated with worse clinical course. Multiple adult ICU trials have suggested that optimization of vitamin D status through high-dose supplementation may reduce mortality and improve other clinically relevant outcomes; however, there have been no trials of rapid normalization in the PICU setting. The objective of this study is to evaluate the safety and efficacy of an enteral weight-based cholecalciferol loading dose regimen in critically ill children with VDD...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29207798/does-vitamin-d-supplementation-improve-glycaemic-control-in-children-with-type-1-diabetes-mellitus-a-randomized-controlled-trial
#15
Shreya Sharma, Niranjan Biswal, Adhisivam Bethou, Medha Rajappa, Sadish Kumar, Vickneshwaran Vinayagam
Introduction: Vitamin D endocrine system is a potential immune system modulator and has been implicated in the pathogenesis of several autoimmune diseases including Type 1 Diabetes Mellitus (T1DM). Studies have demonstrated an inverse risk relationship between T1DM and Vitamin D levels and also, shown a reduced risk of the disease with its supplementation. Aim: To evaluate the role of Vitamin D as an adjuvant in improving glycaemic control and residual pancreatic beta-cell function...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29197860/obesity-is-associated-with-vitamin-d-deficiency-in-danish-children-and-adolescents
#16
Johanne Lind Plesner, Maria Dahl, Cilius Esmann Fonvig, Tenna Ruest Haarmark Nielsen, Julie Tonsgaard Kloppenborg, Oluf Pedersen, Torben Hansen, Jens-Christian Holm
BACKGROUND: Sufficient serum concentrations of vitamin D are required to maintain bone health during growth. The aims of this study were to determine whether vitamin D deficiency is more prevalent among children and adolescents with obesity compared to their normal weight peers and to identify clinical and biochemical variables associated with vitamin D deficiency. METHODS: One thousand four hundred and eighty-four children and adolescents with overweight/obesity and 2143 population-based controls were recruited from the Danish Childhood Obesity Biobank...
December 4, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29197669/vitamin-d-deficiency-in-children-with-epilepsy-taking-valproate-and-levetiracetam-as-monotherapy
#17
Teodoro Durá-Travé, Fidel Gallinas-Victoriano, María Malumbres-Chacón, Paula Moreno-Gónzalez, Sergio Aguilera-Albesa, María Eugenia Yoldi-Petri
OBJECTIVE: The aim of this study is to evaluate if valproate (VPA) and levetiracetam (LEV) as monotherapy are associated with vitamin D deficiency among children with epilepsy. MATERIAL & METHODS: A cross-sectional clinical (seizure types, aetiology of epilepsy, dosage, drug levels, and duration of AED treatment) and blood testing (calcium, phosphorus, 25-OHD and PTH) study was accomplished in 90 epileptic children (AED group: 59 receiving VPA, and 31 receiving LEV) and a control group (244 healthy subjects)...
November 30, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/29187063/nutrition-deficiencies-in-children-with-intestinal-failure-receiving-chronic-parenteral-nutrition
#18
Shweta S Namjoshi, Sarah Muradian, Hannah Bechtold, Laurie Reyen, Robert S Venick, Elizabeth A Marcus, Jorge H Vargas, Laura J Wozniak
BACKGROUND: Home parenteral nutrition (PN) is a lifesaving therapy for children with intestinal failure (IF). Our aims were to describe the prevalence of micronutrient deficiencies (vitamin D, zinc, copper, iron, selenium) in a diverse population of children with IF receiving PN and to identify and characterize risk factors associated with micronutrient deficiencies, including hematologic abnormalities. METHODS: Data were collected on 60 eligible patients through retrospective chart review between May 2012 and February 2015...
February 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29178404/the-impact-of-rickets-on-growth-and-morbidity-during-recovery-among-children-with-complicated-severe-acute-malnutrition-in-kenya-a-cohort-study
#19
Moses M Ngari, Johnstone Thitiri, Laura Mwalekwa, Molline Timbwa, Per Ole Iversen, Greg W Fegan, James A Berkley
The effects of rickets on children recovery from severe acute malnutrition (SAM) are unknown. Rickets may affect both growth and susceptibility to infectious diseases. We investigated the associations of clinically diagnosed rickets with life-threatening events and anthropometric recovery during 1 year following inpatient treatment for complicated SAM. This was a secondary analysis of clinical trial data among non-human immunodeficiency virus-infected Kenyan children with complicated SAM (2-59 months) followed for 1 year posthospital discharge (ClinicalTrials...
November 27, 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29176461/impact-of-hydroxyurea-on-anthropometry-and-serum-25-hydroxyvitamin-d-among-children-with-sickle-cell-disease
#20
Samuel A Adegoke, Josefina A P Braga, Adekunle D Adekile, Maria S Figueiredo
OBJECTIVE: To evaluate the impact of hydroxyurea (HU) on nutritional status and serum 25-hydroxyvitamin D (25-OHD) of children with sickle cell disease (SCD). DESIGN: Anthropometry and serum 25-OHD were determined in 98 children with SCD, comprising of 68 in HU-group and 30 in HU-naive group. RESULTS: Underweight was more common among HU-naive group (33.3% vs. 10.3%, P=0.009), while 79.4% of HU-group against 56.7% HU-naive had normal body mass index percentile for age and sex, P=0...
November 23, 2017: Journal of Pediatric Hematology/oncology
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