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vitamin d deficiency in children

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https://www.readbyqxmd.com/read/28631133/bone-density-in-pediatric-crohn-s-disease-a-cross-sectional-observation-from-south-india
#1
Shiraz Salim Khan, Sagar S Patil
BACKGROUND: Crohn's disease (CD) frequently manifests in the second and third decades of life. Malnutrition and corticosteroid therapy may affect bone mineralization and delay bone growth. Our aim was to study bone mineral density and factors associated low bone mineral density (BMD) in pediatric CD. METHODS: A cross-sectional observational study in children with CD (aged 5 to <18 years) was done. Demographic and treatment details were noted. Vitamin D levels <20 ng/mL were considered as deficiency...
June 20, 2017: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/28628759/do-infants-with-cow-s-milk-protein-allergy-have-inadequate-levels-of-vitamin-d
#2
Cristiane M Silva, Silvia A da Silva, Margarida M de C Antunes, Gisélia Alves Pontes da Silva, Emanuel Sávio Cavalcanti Sarinho, Kátia G Brandt
OBJECTIVE: To verify whether infants with cow's milk protein allergy (CMPA) have inadequate vitamin D levels. METHODS: This cross-sectional study included 120 children aged 2 years or younger, one group with CMPA and a control group. The children were recruited at the pediatric gastroenterology, allergology, and pediatric outpatient clinics of a university hospital in the Northeast of Brazil. A questionnaire was administered to the caregiver and blood samples were collected for vitamin D quantification...
June 16, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28626104/-prevalence-of-vitamin-d-insufficiency-deficiency-among-overweight-and-obese-preschool-children-in-%C3%A2-yuelu-district-of-changsha
#3
Yifu He, Ming Cai, Xin Huang
To investigate the prevalence of vitamin D insufficiency/deficiency among 3-5 years old overweight and obese children in Yuelu district of Changsha and to give scientific suggestion for children health promotion.
 Methods: Based on the stratified cluster sampling method, 2 872 children aged 3-5 years old from Yuelu district were enrolled from Oct to Dec 2015. All participants have received biochemical and physical examination. According to the body mass index, the prevalence rates of vitamin D insufficiency [serum 25(OH)D level 20-<30 ng/mL] and deficiency [serum 25(OH)D level<20 ng/mL] among normal weight, overweight/obese children were calculated, respectively...
May 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28625040/vitamin-d-status-in-under-five-children-with-a-history-of-close-tuberculosis-contact-in-padang-west-sumatra
#4
Finny Fitry Yani, Nur Indrawaty Lipoeto, Bambang Supriyatno, Eryati Darwin, Darfioes Basir
BACKGROUND AND OBJECTIVE: Serum vitamin D influences cellular immunity against Mycobacterium tuberculosis, particularly in under-five children. Vitamin D insufficiency and deficiency as well as tuberculosis (TB) are highly prevalent in Indonesia. This study described the association of serum vitamin D in the incidence of latent TB in under-five children with a history of close TB contact. METHODS AND STUDY DESIGN: This cross-sectional study examined 178 under-five children with a history of close TB contact, with 98 index cases from primary health care facilities in Padang...
June 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28608241/vit-d-deficiency-is-a-possible-risk-factor-in-ars
#5
Mustafa Suphi Elbistanlı, Hasan Emre Koçak, Selçuk Güneş, Harun Acıpayam, Baver Maşallah Şimşek, Sinan Canpolat, Fatma Tülin Kayhan
Vitamin D deficiency is effective in the development of acute rhinosinusitis and prolongation of inflammation by increasing inflammation in the sinonasal epithelium. Vitamin D deficiency is important in the development of bone barriers that prevent the complication of acute rhinosinusitis. Although Vitamin D levels may be a variable risk factor for various respiratory tract disorders, there are limited data on the role in sinonasal infections. Our aim was to investigate the association of 25-hydroxy-vitamin D (25OHD) levels with acute rhinosinusitis (ARS) and preseptal cellulitis complications...
June 12, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28607944/vitamin-d-deficient-rickets-in-japan
#6
Mitsuko Itoh, Jun Tomio, Satoshi Toyokawa, Mayuko Tamura, Tsuyoshi Isojima, Sachiko Kitanaka, Yasuki Kobayashi
Objectives: Our study aimed to clarify the trend of vitamin D deficiency and rickets diagnosed in the past 10 years. Methods: This observational study used health insurance claims data from 2005 to 2014. The number of beneficiaries for 2005 and 2014 were 91 617 and 365 800, respectively. We included children aged 0 to 15 years diagnosed with vitamin D deficiency or vitamin D-deficient rickets; those with congenital/secondary rickets and low-birth-weight infants were excluded. We analyzed the number of patients and the temporal trend of these diseases in Japan...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/28604131/micronutrient-intake-and-the-contribution-of-dietary-supplements-in-hispanic-infants
#7
Kiara Amaro-Rivera, Andrea López-Cepero, Beatriz Diaz, Jae Eun Lee, Cristina Palacios
To calculate micronutrient adequacy among infants and toddlers and to determine the contribution of dietary supplements to this adequacy, micronutrient intake was assessed using two nonconsecutive 24-hour recalls in a sample of 296 infants aged 0-24 months. Micronutrient intake was calculated from foods and beverages and from supplements and compared between nonusers and users of supplements. Percentages of children below the Dietary Reference Intake (DRI) and above the tolerable upper limit intake (UL) were also compared between groups...
June 12, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/28588900/associations-between-serum-25-oh-d-concentrations-and-prevalent-asthma-among-children-living-in-communities-with-differing-levels-of-urbanization-a-cross-sectional-study
#8
Suzanne L Pollard, John J Lima, Karina Romero, Carla Tarazona-Meza, Edward Mougey, Katherine Tomaino, Gary Malpartida-Guzmán, Nadia N Hansel, William Checkley
BACKGROUND: Prior evidence suggests that vitamin D deficiency may increase the risk of asthma and atopy and impair pulmonary function in children. METHODS: In this cross-sectional analysis nested in a case-control study, we analyzed serum 25(OH)D concentrations in 413 children with asthma and 471 children without asthma living in two geographically adjacent study communities (Pampas and Villa El Salvador). We measured total and antigen-specific IgE levels, pulmonary function, asthma control, and exhaled nitric oxide...
2017: Asthma research and practice
https://www.readbyqxmd.com/read/28554929/nutritional-rickets-in-norway-a-nationwide-register-based-cohort-study
#9
Haakon E Meyer, Kristina Skram, Ingvill Almås Berge, Ahmed A Madar, Hilde Johanne Bjørndalen
OBJECTIVES: Poor vitamin D status has been reported to be highly prevalent in many non-western immigrant groups living in Norway and other western countries. However, data on rickets are scarce, and the aim of the current study was to identify new cases of nutritional rickets in Norway in the period 2008-2012 among children under the age of 5 years. DESIGN: Register-based cohort study. SETTING: The Norwegian population from 2008 to 2012. PARTICIPANTS: Children with nutritional rickets under the age of 5 years...
May 29, 2017: BMJ Open
https://www.readbyqxmd.com/read/28550622/genomic-instability-related-to-zinc-deficiency-and-excess-in-an-in-vitro-model-is-the-upper-estimate-of-the-physiological-requirements-recommended-for-children-safe
#10
Gisel Padula, María Virginia Ponzinibbio, Rocío Celeste Gambaro, Analía Isabel Seoane
Micronutrients are important for the prevention of degenerative diseases due to their role in maintaining genomic stability. Therefore, there is international concern about the need to redefine the optimal mineral and vitamin requirements to prevent DNA damage. We analyzed the cytostatic, cytotoxic, and genotoxic effect of in vitro zinc supplementation to determine the effects of zinc deficiency and excess and whether the upper estimate of the physiological requirement recommended for children is safe. To achieve zinc deficiency, DMEM/Ham's F12 medium (HF12) was chelated (HF12Q)...
May 26, 2017: In Vitro Cellular & Developmental Biology. Animal
https://www.readbyqxmd.com/read/28542114/predictors-of-pouchitis-after-ileal-pouch-anal-anastomosis-in-pediatric-onset-ulcerative-colitis
#11
Firas Rinawi, Amit Assa, Rami Eliakim, Yael Mozer Glassberg, Vered Nachmias Friedler, Yaron Niv, Yoram Rosenbach, Ari Silbermintz, Noam Zevit, Raanan Shamir
OBJECTIVES: Few studies have reported on the incidence and risk factors for pouchitis following colectomy and ileal pouch-anal anastomosis (IPAA) in patients with pediatric-onset ulcerative colitis (UC). We aimed to determine clinical predictors for the development of pouchitis following IPAA in this population. PATIENTS AND METHODS: We performed a retrospective chart review of all pediatric UC cases that were diagnosed at the Schneider Children's Medical Center of Israel between 1981 and 2013 and who underwent colectomy during disease course...
May 24, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28534725/vitamin-d-deficiency-and-sufficiency-among-canadian-children-residing-at-high-latitude-following-the-revision-of-the-rda-of-vitamin-d-intake-in-2010-corrigendum
#12
Lalani L Munasinghe, Yan Yuan, Noreen D Willows, Erin L Faught, John P Ekwaru, Paul J Veugelers
No abstract text is available yet for this article.
April 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28532484/seasonal-variations-of-vitamin-d-and-its-relation-to-lipid-profile-in-iranian-children-and-adults
#13
Sakineh Nouri Saeidlou, Davoud Vahabzadeh, Fariba Babaei, Zakaria Vahabzadeh
BACKGROUND: Vitamin D has a multitude of functional properties and acts like a hormone in the body. Its effect on the lipid profile is one of the proposed mechanisms for its relationship with many disorders during its deficiency. But, this relationship is still conflicting and debatable, so this study was conducted to determine the association between serum level of vitamin D and lipid profiles, including serum concentrations of cholesterol, triglyceride (TG), HDL, and LDL in healthy subjects...
May 22, 2017: Journal of Health, Population, and Nutrition
https://www.readbyqxmd.com/read/28531780/vitamin-d-status-and-the-effects-of-oral-vitamin-d-treatment-in-children-with-vitiligo-a-prospective-study
#14
Gülay Karagüzel, Nil P Sakarya, Sevgi Bahadır, Selçuk Yaman, Ayşenur Ökten
BACKGROUND & AIMS: Vitiligo is a pigmentary disorder and autoimmune pathogenesis seems most likely. Decreased vitamin D levels have been related to several autoimmune diseases. Little is known about the association of vitiligo and vitamin D. We aimed to evaluate serum 25-hydroxyvitamin D [25(OH)D] levels in children with vitiligo and to determine the efficacy of oral vitamin D therapy on the repigmentation of vitamin D deficient patients. METHODS: Thirty patients aged 6-17 years with vitiligo and 30 sex- and age-matched apparently healthy controls were included in this prospective study...
October 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28513555/effect-of-low-dose-vitamin-d-supplementation-on-serum-25-oh-d-in-school-children-and-white-collar-workers
#15
Ronghua Zhang, Xiamusiye Muyiduli, Danting Su, Biao Zhou, Yueqiang Fang, Shuying Jiang, Shuojia Wang, Lichun Huang, Minjia Mo, Minchao Li, Bule Shao, Yunxian Yu
OBJECTIVE: Our study aimed to investigate the nutritional vitamin D status of school children aged 9-15 years and white-collar workers in Zhejiang province, and evaluate the efficacy of low-dose-oral vitamin D supplementation in both populations. METHODS: We conducted a prospective controlled trial during March 2014 to November 2015, comparing the efficacy of vitamin D supplements (400 IU/day) with non-intervention for 18 months in school children aged 9-15 years...
May 17, 2017: Nutrients
https://www.readbyqxmd.com/read/28508087/the-vitamin-d-for-enhancing-the-immune-system-in-cystic-fibrosis-disc-trial-rationale-and-design-of-a-multi-center-double-blind-placebo-controlled-trial-of-high-dose-bolus-administration-of-vitamin-d3-during-acute-pulmonary-exacerbation-of-cystic-fibrosis
#16
Vin Tangpricha, Ellen M Smith, Jose Binongo, Suzanne E Judd, Thomas R Ziegler, Seth Walker, Rabindra Tirouvanziam, Susu M Zughaier, Moon Jeong Lee, Supavit Chesdachai, Wendy A Hermes, James F Chmiel, Amit Gaggar, Ruth E Grossmann, Patricia M Joseph, Jessica A Alvarez
Vitamin D deficiency is highly prevalent in children and adults with cystic fibrosis (CF). Recent studies have found an association between vitamin D status and risk of pulmonary exacerbations in children and adults with CF. The ongoing Vitamin D for enhancing the Immune System in Cystic fibrosis (DISC) study is a multi-center, double-blind, randomized, placebo-controlled trial that will test the hypothesis of whether high dose vitamin D given as a single oral bolus of 250,000 IU to adults with CF during a pulmonary exacerbation followed by a maintenance dose of vitamin D will improve time to next pulmonary exacerbation and re-hospitalization, improve survival and lung function compared to placebo and reduce the rates of pulmonary exacerbation,...
June 2017: Contemporary Clinical Trials Communications
https://www.readbyqxmd.com/read/28504486/high-prevalence-of-vitamin-d-deficiency-among-children-with-chronic-kidney-disease-and-kidney-transplant
#17
Paula Coccia, Juliana Blazquez, Maritza Contreras, Verónica Ferrais, Claudia Raddavero, Lidia Ghezzi, Julio Busaniche, Gonzalo Beneitez, Andrea Kozak, Jorge Ferraris
INTRODUCTION: Vitamin D (25(OH)D) deficiency is common among patients with chronic kidney disease (CKD). Our objective was to establish the prevalence of 25(OH)D deficiency among children with CKD and identify risk factors. A correlation was observed between 25(OH)D and parathormone intact molecule. POPULATION AND METHODS: Cross-sectional study conducted between January 2013 and December 2015. Patients younger than 19 years old with and without CKD were included...
June 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28481882/vitamin-d-supplementation-and-growth-in-urban-mongol-school-children-results-from-two-randomized-clinical-trials
#18
Davaasambuu Ganmaa, Jennifer J Stuart, Nyamjav Sumberzul, Boldbaatar Ninjin, Edward Giovannucci, Ken Kleinman, Michael F Holick, Walter C Willett, Lindsay A Frazier, Janet W Rich-Edwards
BACKGROUND: Symptomatic vitamin D deficiency is associated with slowed growth in children. It is unknown whether vitamin D repletion in children with asymptomatic serum vitamin D deficiency can restore normal growth. OBJECTIVE: We tested the impact of vitamin D-supplementation on serum concentrations of 25-hydroxyvitamin D [25(OH)D] and short-term growth in Mongol children, with very low serum vitamin D levels in winter. DESIGN: We conducted two randomized, double-blind, placebo-controlled trials in urban school age children without clinical signs of rickets...
2017: PloS One
https://www.readbyqxmd.com/read/28472874/associations-of-seasonal-patterns-and-vitamin-d-levels-with-onset-and-flares-of-pediatric-inflammatory-bowel-disease
#19
Yael Brandvayman, Firas Rinawi, Raanan Shamir, Amit Assa
BACKGROUND: As inflammatory bowel disease (IBD) might be associated with environmental factors such as seasonal patterns and low vitamin D levels we aimed to assess their association with IBD onset and flares in a large cohort of children. METHODS: The records of 623 pediatric onset IBD patients were reviewed retrospectively including age at onset, gender, severity indices, month of first symptom, and vitamin D levels at diagnosis. For a subgroup of patients, data included date of first flare and vitamin D levels during flare and remission...
May 4, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/28470840/vitamin-d-deficiency-causes-rickets-in-an-urban-informal-settlement-in-kenya-and-is-associated-with-malnutrition
#20
Kelsey D J Jones, C Ulrich Hachmeister, Maureen Khasira, Lorna Cox, Inez Schoenmakers, Caroline Munyi, H Samira Nassir, Barbara Hünten-Kirsch, Ann Prentice, James A Berkley
The commonest cause of rickets worldwide is vitamin D deficiency, but studies from sub-Saharan Africa describe an endemic vitamin D-independent form that responds to dietary calcium enrichment. The extent to which calcium-deficiency rickets is the dominant form across sub-Saharan Africa and in other low-latitude areas is unknown. We aimed to characterise the clinical and biochemical features of young children with rickets in a densely populated urban informal settlement in Kenya. Because malnutrition may mask the clinical features of rickets, we also looked for biochemical indices of risk in children with varying degrees of acute malnutrition...
May 3, 2017: Maternal & Child Nutrition
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