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Pain epidemiology

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https://www.readbyqxmd.com/read/29440012/patterns-of-regional-variation-of-opioid-prescribing-in-primary-care-in-england-a-retrospective-observational-study
#1
Luke Mordecai, Carl Reynolds, Liam J Donaldson, Amanda C de C Williams
BACKGROUND: Opioids are a widely prescribed class of drug with potentially harmful short-term and long-term side effects. There are concerns about the amounts of these drugs being prescribed in England given that they are increasingly considered ineffective in the context of long-term non-cancer pain, which is one of the major reasons for their prescription. AIM: To assess the amount and type of opioids prescribed in primary care in England, and patterns of regional variation in prescribing...
February 12, 2018: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/29430564/sensory-symptom-profiles-differ-between-trigeminal-and-thoracolumbar-postherpetic-neuralgia
#2
Stefanie Rehm, Moritz Groβkopf, Maria Kabelitz, Thomas Keller, Rainer Freynhagen, Thomas R Tölle, Ralf Baron
Introduction: Animal experimental evidence suggests that mechanisms of pain generation and response to treatment differ between neuropathic pain in the cephalic and the extracephalic innervation territories. Objectives: The objective of the study was to examine whether in humans an identical peripheral painful neuropathy is associated with different pain qualities and sensory abnormalities in the face as compared with the thoracic region. Methods: We retrospectively analysed epidemiological and clinical data of 639 patients with postherpetic neuralgia (PHN) in the face and at the trunk who were collected within a cross-sectional cohort survey and compared the respective sensory symptom profiles captured with the painDETECT questionnaire...
January 2018: Pain Reports (Baltimore, Md.)
https://www.readbyqxmd.com/read/29429005/new-frontier-cancer-pain-management-clinical-fellowship
#3
Uri Hochberg, Jordi Perez, Manuel Borod
Cancer pain is a multi-dimensional experience, varies from person to person both physically and psycho-socially, and impacts all aspects of the patients' quality of life. Majority of patients with an advanced or metastatic cancer will experience pain. It is estimated that as many as half of cancer patients are under-treated and as many as 20% experience pain refractory to the conventional WHO ladder of pain management. The McGill University Health Centre (MUHC) Cancer Pain Clinic (CPC) was created to meet the needs of those patients with a diagnosis of cancer whose pain had become a main symptom and those who failed to respond to conventional treatment...
February 10, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29428452/association-between-dietary-glycemic-index-and-knee-osteoarthritis-the-korean-national-health-and-nutrition-examination-survey-2010-2012
#4
Min Wook So, Sunggun Lee, Seong-Ho Kim
BACKGROUND: Obesity and metabolic abnormalities are important risk factors for knee osteoarthritis (KOA). Recent epidemiologic studies have found that a high glycemic index (GI) and glycemic load (GL) diet are associated with a higher risk for metabolic complications and cardiovascular mortality. OBJECTIVE: We aimed to examine the association between dietary GI, dietary GL, and KOA among Korean adults. DESIGN: This was a cross-sectional study that analyzed data obtained from the Korean National Health and Nutrition Examination Survey 2010-2012...
February 7, 2018: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/29427812/chronic-pain-and-its-association-with-obesity-among-older-adults-in-china
#5
Jie Li, Jian Chen, Qirong Qin, Dongdong Zhao, Bao Dong, Qiongqiong Ren, Dandan Yu, Peng Bi, Yehuan Sun
OBJECTIVES: There is a paucity of epidemiological data on chronic pain and obesity among older adults. This study attempted to present the characterization of chronic pain and its association with obesity among the Chinese elderly. METHODS: A cross-sectional survey was undertaken among 6524 elderly individuals aged ≥60 years in China. Chronic pain was identified by self-reports based on the definition from the International Association for the Study of Pain (IASP)...
February 6, 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29427091/current-clinical-and-bacteriological-profile-of-septic-arthritis-in-young-infants-a-prospective-study-from-a-tertiary-referral-centre
#6
Gireesh Sankaran, Balaji Zacharia, Antony Roy, Sulaikha Puthan Purayil
PURPOSE: The study was carried out to evaluate the clinical and bacteriological profile of SA in young infants (age ≤ 3 months) in a tertiary referral centre and to assess the risk factors and to document the changing trends in the epidemiology. METHODS: This was a prospective descriptive study on all young infants with SA. Clinical and perinatal history, examination, radiological and laboratory findings (blood count, ESR, CRP, blood and joint cultures) were studied...
February 9, 2018: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29421808/pathophysiology-of-functional-gastrointestinal-disorders-a-holistic-overview
#7
Gerald Holtmann, Ayesha Shah, Mark Morrison
Background and Summary: Traditionally, functional gastrointestinal disorders (FGID), including functional dyspepsia or irritable bowel syndrome (IBS), are defined by more or less specific symptoms and the absence of structural or biochemical abnormalities that cause these symptoms. This concept is now considered to be outdated; if appropriate tests are applied, structural or biochemical abnormalities that explain or cause the symptoms may be found in many patients. Another feature of FGID are the highly prevalent psychiatric comorbidities, such as depression and anxiety...
February 8, 2018: Digestive Diseases
https://www.readbyqxmd.com/read/29417493/depression-in-multiple-sclerosis-epidemiology-aetiology-diagnosis-and-treatment
#8
REVIEW
Claudio Solaro, Giulia Gamberini, Fabio Giuseppe Masuccio
Depressive disorders are common in patients with multiple sclerosis, influencing their quality of life and adherence to treatments, as well as becoming more frequent with the progression of the disease and in the secondary progressive form of multiple sclerosis. Patients with multiple sclerosis often experience a typical cluster of symptoms in association with depression, such as fatigue, pain and cognitive impairment. However, the pathogenesis of multiple sclerosis-related depression remains partially unclear, even though genetic, immune-inflammatory and psychosocial factors might be seen to play a role, in addition to the brain structural alterations documented by magnetic resonance imaging studies...
February 7, 2018: CNS Drugs
https://www.readbyqxmd.com/read/29417134/opioid-prescribing-patterns-and-complications-in-the-dermatology-medicare-population
#9
Severine Cao, Ryan Karmouta, David G Li, Ryan S Din, Arash Mostaghimi
Importance: The ongoing opioid epidemic in the United States has been fueled by prescription opioids. Increases in opioid-related deaths and complications mandate clinicians in all fields to scrutinize their prescribing patterns. Objective: To characterize the current status and potential complications of opioid prescribing practices among dermatologists for Medicare beneficiaries. Design, Setting, and Participants: A cross-sectional study used Medicare Part D prescriber data to evaluate opioid prescriptions by dermatologists from January 1 to December 31, 2014...
February 7, 2018: JAMA Dermatology
https://www.readbyqxmd.com/read/29414454/recognition-of-unprovoked-idiopathic-pulmonary-embolism-prospective-observational-study
#10
Natalia Stoeva, Galina Kirova, Milena Staneva, Diana Lekova, Anton Penev, Rumiana Bakalova
BACKGROUND: The assessment of the clinical symptoms is the weakest link of the pulmonary embolism (PE) diagnostic algorithm. Despite the presence of highly sensitive and specific imaging methods, verifying PE remains difficult due to nonspecific clinical symptoms and frequently its subclinical course. OBJECTIVE: The aim of this study is to improve the recognition of PE by investigating the clinical presentation and short-term prognosis of unprovoked PE in comparison to provoked PE...
February 2018: Respiratory Medicine
https://www.readbyqxmd.com/read/29414183/hepatitis-e-outbreak-at-a-nursing-home-for-aged-people-in-hokkaido-japan-between-february-and-march-2016
#11
Setsuko Ishida, Kaori Matsuura, Shima Yoshizumi, Masahiro Miyoshi, Takahisa Sugisawa, Mitsuhiro Tanida, Motohiko Okano
BACKGROUND: Infection with hepatitis E virus (HEV) genotypes 3 and 4 are usually asymptomatic but can occasionally result in life-threatening acute hepatitis. To date, only sporadic cases together with a few outbreaks have been documented. Seroprevalence studies with assays for the detection of HEV IgG antibodies, suggest that HEV is more prevalent than previously thought, even in non-endemic regions. OBJECTIVES: The aim of this study was to characterize an outbreak of hepatitis E (HE) in a nursing home for aged people between February and March 2016...
January 29, 2018: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/29412042/musculoskeletal-pain-and-menopause
#12
Fiona E Watt
Musculoskeletal pain, arthralgia and arthritis are all more common in women, and their frequency increases with age and in some appears to be associated with the onset of menopause. The clinical assessment, investigation and management of women presenting with musculoskeletal pain, arthralgia or arthritis at the time of menopause are reviewed. Common causes of arthralgia and arthritis in this population are discussed. The epidemiological and trials evidence for the effects of hormone replacement therapy on musculoskeletal pain and arthritis (primarily from RCTs of HRT for other menopausal symptoms) are discussed...
January 1, 2018: Post Reproductive Health
https://www.readbyqxmd.com/read/29410495/leisure-time-physical-activity-participation-in-individuals-with-spinal-cord-injury-in-malaysia-barriers-to-exercise
#13
Maziah Mat Rosly, Mark Halaki, Nazirah Hasnan, Hadi Mat Rosly, Glen M Davis, Ruby Husain
STUDY DESIGN: Cross-sectional. OBJECTIVES: An epidemiological study describing leisure time physical activities (LTPA) and the associations of barriers, sociodemographic and injury characteristics to moderate-vigorous aerobic exercise participation among individuals with spinal cord injury (SCI) in a developing Southeast Asian country. SETTING: SCI community in Malaysia. METHODS: The study sample consisted of 70 participants with SCI...
February 6, 2018: Spinal Cord
https://www.readbyqxmd.com/read/29409933/signs-and-symptoms-in-1043-patients-with-complex-regional-pain-syndrome-crps
#14
Stephan Ott, Christian Maihöfner
Complex regional pain syndrome (CRPS) is a complex pain disorder that can emerge after limb trauma or a lesion in the peripheral nervous system. Typical features include continuing pain, sensory, vasomotor, sudomotor, motor and trophic changes as well as edema. These signs provide the basis of CRPS diagnosis. A detailed description of the signs, symptoms and medical history of CRPS could potentially facilitate an earlier and more accurate diagnosis. The aim of this study is to provide such a description, based on epidemiological measures, clinical presentation and a thorough description of pain sensations...
February 1, 2018: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29406791/functional-abdominal-pain-disorders-in-children
#15
Shaman Rajindrajith, Judith Zeevenhooven, Niranga Manjuri Devanarayana, Bonaventure Jayasiri Crispus Perera, Marc A Benninga
Chronic abdominal pain is a common problem in pediatric practice. The majority of cases fulfill the Rome IV criteria for functional abdominal pain disorders (FAPDs). At times, these disorders may lead to rather serious repercussions. Area covered: We have attempted to cover current knowledge on epidemiology, pathophysiology, risk factors related to pathophysiology, clinical evaluation and management of children with FAPDs. Expert commentary: FAPDs are a worldwide problem with a pooled prevalence of 13.5%. There are a number of predisposing factors and pathophysiological mechanisms including stressful events, child maltreatment, visceral hypersensitivity, altered gastrointestinal motility and change in intestinal microbiota...
February 16, 2018: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29404787/complex-regional-pain-syndrome-current-concepts-and-treatment-options
#16
REVIEW
Ivan Urits, Abra H Shen, Mark R Jones, Omar Viswanath, Alan D Kaye
PURPOSE OF REVIEW: Complex regional pain syndrome (CRPS) refers to a chronic pain condition that is characterized by progressively worsening spontaneous regional pain without dermatomal distribution. The symptomatology includes pain out of proportion in time and severity to the inciting event. The purpose of this review is to present the most current information concerning epidemiology, diagnosis, pathophysiology, and therapy for CRPS. RECENT FINDINGS: In recent years, discovery of pathophysiologic mechanisms of CRPS has led to significant strides in the understanding of the disease process...
February 5, 2018: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/29402732/female-sexual-dysfunction-a-systematic-review-of-outcomes-across-various-treatment-modalities
#17
REVIEW
James M Weinberger, Justin Houman, Ashley T Caron, Jennifer Anger
BACKGROUND: Female sexual dysfunction (FSD) is a highly prevalent condition. Nevertheless, the scientific literature has only recently begun to accumulate evidence for treatment modalities that address the underlying etiologies of FSD. AIM: The purpose of this systematic review is to elucidate what treatments are effective across the various symptom complexes of FSD. METHODS: Utilizing Meta-analysis of Observational Studies in Epidemiology guidelines, we conducted a systematic review of PubMed, EMBASE, clinicaltrials...
February 3, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29398248/epidemiological-characteristics-safety-and-efficacy-of-medical-cannabis-in-the-elderly
#18
Ran Abuhasira, Lihi Bar-Lev Schleider, Raphael Mechoulam, Victor Novack
INTRODUCTION: There is a substantial growth in the use of medical cannabis in recent years and with the aging of the population, medical cannabis is increasingly used by the elderly. We aimed to assess the characteristics of elderly people using medical cannabis and to evaluate the safety and efficacy of the treatment. METHODS: A prospective study that included all patients above 65 years of age who received medical cannabis from January 2015 to October 2017 in a specialized medical cannabis clinic and were willing to answer the initial questionnaire...
February 1, 2018: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/29397242/a-rare-case-of-acute-right-sided-colonic-diverticulitis-presenting-as-pancreatitis
#19
Maria de Lourdes Ladino Sturchler, Evan A Rusoja, Arun Nagdev, Barry C Simon
BACKGROUND: This case report highlights the clinical presentation, radiologic findings, and medical management of a case of right colonic diverticulitis (RCD) with concomitant pancreatitis, a rare and easily missed entity in the emergency department (ED) of Western hemisphere countries. In our report, we present and discuss a case of RCD that led to pancreatitis in a female Asian patient. We review the epidemiology, diagnosis, and management of this disorder, and also discuss some complications associated with RCD...
January 31, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29396128/irritable-bowel-syndrome-and-endometriosis-new-insights-for-old-diseases
#20
REVIEW
Davide Viganò, Federica Zara, Paolo Usai
Irritable bowel syndrome and endometriosis are two diseases affecting a significant part of the female population, either together or individually, with remarkable consequences in the quality of life. Several studies suggest an epidemiological association between them. Their association may not be just an epidemiological phenomenon, but the manifestation of a pathophysiological correlation, which probably generates a mutual promotion phenomenon. In particular, both clinical entities share the presence of a chronic low-grade inflammatory state at the basis of the disease persistence...
December 27, 2017: Digestive and Liver Disease
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