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Orofacial Pain

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https://www.readbyqxmd.com/read/29783259/classifications-of-temporomandibular-disorders-and-patients-examination-protocols-comparative-analysis-by-the-convenience-of-their-daily-use-in-clinical-practice
#1
Ulyana D Telishevska, Oksana D Telishevska
OBJECTIVE: Introduction:The problem of temporomandibular disorders (TMD) is relevant in today's world and is considered one of the most common pathologies causing nonodontogenic pain syndromes of maxillofacial region. The morbidity of temporomandibular disorders is 27 to 76% among patients who seek dental care. There is now a significant number of classifications of TMD, however, clinically convenient, morphologically and pathogenetically substantiated classification of temporomandibular joint's (TMJ) conditions has not yet been developed...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29782036/differential-diagnosis-of-jaw-pain-using-informatics-technology
#2
Yoon Nam, Hong-Gee Kim, Hong-Seop Kho
This study aimed to deduce evidence-based clinical clues that differentiate temporomandibular disorders (TMD)-mimicking conditions from genuine TMD by text mining using natural language processing (NLP) and recursive partitioning. We compared the medical records of 29 patients diagnosed with TMD-mimicking conditions and 290 patients diagnosed with genuine TMD. Chief complaints and medical histories were preprocessed via NLP to compare the frequency of word usage. In addition, recursive partitioning was used to deduce the optimal size of mouth opening, which could differentiate TMD-mimicking from genuine TMD groups...
May 21, 2018: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/29769194/orofacial-pain
#3
Adonye Banigo, David Watson, Bhaskar Ram, Kim Ah-See
No abstract text is available yet for this article.
May 16, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29767652/peripheral-glial-cell-line-derived-neurotrophic-factor-facilitates-the-functional-recovery-of-mechanical-nociception-following-inferior-alveolar-nerve-transection-in-rats
#4
Masahiro Watanabe, Masamichi Shinoda, Dulguun Batbold, Naoyuki Sugano, Shuichi Sato, Koichi Iwata
AIMS: To identify endogenous sources of glial cell line-derived neurotrophic factor (GDNF) at the injury site following inferior alveolar nerve transection (IANX) and to determine whether GDNF signaling promotes the recovery of orofacial pain sensation. METHODS: Nociceptive mechanical sensitivity of the facial skin was assessed following IANX (n = 10) or sham operation (n = 7). GDNF-positive cells were identified and the amount of GDNF measured in the injured region of IANX rats (n = 10) and in sham rats (n = 10)...
May 15, 2018: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/29767648/antinociception-induced-by-copper-salt-revisited-interaction-with-ketamine-in-formalin-induced-intraplantar-and-orofacial-pain-in-mice
#5
Victoria Cazanga, Alejandro Hernandez, Bernardo Morales, Teresa Pelissier, Luis Constandil
AIMS: To evaluate in mice the antinociceptive effect of copper in spinal and trigeminal nociceptive pathways by using the intraplantar and orofacial formalin tests, respectively, and to examine whether this effect may interact synergistically with ketamine-induced antinociception. METHODS: Nociceptive behaviors (licking/biting of the formalin-injected limb and rubbing/scratching of the formalin-injected orofacial area) in male mice were evaluated during a 45-minute observation period post-formalin injection...
May 15, 2018: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/29763576/g-i-protein-functions-in-thalamic-neurons-to-decrease-orofacial-nociceptive-response
#6
Jennifer Strand, Crystal Stinson, Larry L Bellinger, Yuan Peng, Phillip R Kramer
Orofacial pain includes neuronal pathways that project from the trigeminal nucleus to and through the thalamus. What role the ventroposterior thalamic complex (VP) has on orofacial pain transmission is not understood. To begin to address this question an inhibitory G protein (Gi) designer receptor exclusively activated by a designer drug (DREADD) was transfected in cells of the VP using adeno-associated virus isotype 8. Virus infected cells were identified by a fluorescent tag and immunostaining. Cells were silenced after injecting the designer drug clozapine-n-oxide, which binds the designer receptor activating Gi ...
May 12, 2018: Brain Research
https://www.readbyqxmd.com/read/29750100/orofacial-clinical-features-in-arnold-chiari-type-i-malformation-a-case-series
#7
José-Alcides de Arruda, Eugênia Figueiredo, João-Luiz Monteiro, Livia-Mirelle Barbosa, Cleomar Rodrigues, Belmiro Vasconcelos
Background: Arnold Chiari malformation (ACM) is characterized by an anatomical defect at the base of the skull where the cerebellum and the spinal cord herniate through the foramen magnum into the cervical spinal canal. Among the subtypes of the condition, ACM type I (ACM-I) is particularly outstanding because of the severity of symptoms. This study aimed to analyze the orofacial clinical manifestations of patients with ACM-I, and discuss their demographic distribution and clinical features in light of the literature...
April 2018: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29746991/electrical-synapses-are-involved-in-orofacial-neuropathic-pain
#8
Omar Ouachikh, Aziz Hafidi, Yves Boucher, Wisam Dieb
Accumulated evidences suggest important roles of glial GAP-junctions in pain. However, only a few studies have explored the role of neuronal GAP-junctions or electrical synapses in neuropathic pain (NP). Therefore, the present study explores the role of connexin 36 (Cx36) in NP using the chronic constriction injury of the infraorbital nerve (CCI-IoN) model in rat. A significant increase in Cx36 labeling was observed in the medullary dorsal horn (MDH) of CCI-IoN-lesioned compared to sham rats. The expression of Cx36 in CCI-IoN-lesioned rats revealed a rostroventral gradient of punctuate labeling within lamina IIo of the MDH...
May 7, 2018: Neuroscience
https://www.readbyqxmd.com/read/29746350/endogenous-pain-modulation-in-chronic-orofacial-pain-a-systematic-review-and-meta-analysis
#9
Estephan J Moana-Filho, Alberto Herrero Babiloni, Nicole R Theis-Mahon
Abnormal endogenous pain modulation (EPM) was suggested as a potential mechanism for chronic pain, i.e., increased pain facilitation and/or impaired pain inhibition underlying symptoms manifestation. EPM function can be tested using psychophysical methods such as temporal summation of pain (TSP) and conditioned pain modulation (CPM), which assess pain facilitation and inhibition, respectively. Several studies have investigated EPM function in patients with non-paroxysmal orofacial pain (OFP) and reported mixed results...
April 26, 2018: Pain
https://www.readbyqxmd.com/read/29738922/behavioral-characteristics-of-capsaicin-mediated-cutaneous-myogenic-and-arthrogenic-orofacial-nociception-in-rats
#10
Eric L Rohrs, John K Neubert, Robert M Caudle, Kyle D Allen
OBJECTIVE: To assess changes in orofacial tactile sensitivity and gnawing related to capsaicin-mediated cutaneous, myogenic, and arthrogenic nociception in the rat. DESIGN: After recovery from anesthesia, orofacial tactile sensitivity and gnawing were assessed using operant testing methods following capsaicin application. Twenty female CD-Hairless rats were tested with bilateral capsaicin cream application to the cheek or with isoflurane anesthesia alone. Following several weeks of recovery, animals (n = 20) received either 10 μL unilateral masseter injections of vehicle, or phosphate buffered saline (PBS) to assess injection sensitization...
April 30, 2018: Archives of Oral Biology
https://www.readbyqxmd.com/read/29727476/diagnostic-criteria-for-temporomandibular-disorders-diagnostic-accuracy-for-general-dentistry-procedure-without-mandatory-commands-regarding-myalgia-arthralgia-and-headache-attributed-to-temporomandibular-disorder
#11
Catharina Österlund, Hannes Berglund, Madeleine Åkerman, Evelina Nilsson, Hanna Petersson, Julia Lam, Per Alstergren
BACKGROUND: The clinical examination in Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) is a strict procedure and comprise mandatory commands. However, learning and using these mandatory commands in general practice have proven to be difficult and their use of DC/TMD is minimal. OBJECTIVES: To investigate if reliability on a diagnostic level for DC/TMD diagnoses differ between examiners using the mandatory commands or not. METHODS: Six examiners were divided into two groups: one using the mandatory commands in DC/TMD for the clinical examination and one that did not use the mandatory commands...
May 4, 2018: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/29707824/psychometric-evaluation-of-the-orofacial-pain-scale-for-non-verbal-individuals-as-a-screening-tool-for-orofacial-pain-in-people-with-dementia
#12
Suzanne Delwel, Roberto S G M Perez, Andrea B Maier, Cees M P M Hertogh, Henrica C W de Vet, Frank Lobbezoo, Erik J A Scherder
OBJECTIVE: The aim of this study was to describe the psychometric evaluation of the Orofacial Pain Scale for Non-Verbal Individuals (OPS-NVI) as a screening tool for orofacial pain in people with dementia. BACKGROUND: The OPS-NVI has recently been developed and needs psychometric evaluation for clinical use in people with dementia. The pain self-report is imperative as a reference standard and can be provided by people with mild-to-moderate cognitive impairment...
April 29, 2018: Gerodontology
https://www.readbyqxmd.com/read/29703278/mission-of-mercy-patient-characteristics-and-dental-related-emergency-department-use
#13
Jolene O Paramore, Jill Boylston Herndon, Andrew B Brown
BACKGROUND: Although dental Mission of Mercy (MOM) events have existed for more than 2 decades and are held in more than 30 states, systematic data collection and reporting on patient characteristics, oral health care use patterns, and oral health care needs are lacking. METHODS: The authors surveyed patients attending the 2016 Florida MOM, asking about their reasons for seeking oral health care, oral health care use, and dental-related emergency department (ED) use...
May 2018: Journal of the American Dental Association
https://www.readbyqxmd.com/read/29697717/analgesic-effects-of-intranasal-ketamine-in-rat-models-of-facial-pain
#14
Rafaela Claudino, Carina Nones, Erika Araya, Juliana Chichorro
AIMS: To assess the analgesic effect of intranasal administration of S-ketamine in different rat models of facial pain. METHODS: Nociceptive responses induced by formalin injected into the upper lip and facial hyperalgesia induced by capsaicin or carrageenan injected into the upper lip were used to evaluate the analgesic effect of intranasal ketamine in acute facial pain models in rats (n = 173). The effect of intranasal ketamine on heat and mechanical hyperalgesia induced by constriction of the infraorbital nerve (CION) was also evaluated...
April 25, 2018: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/29694490/bundle-of-measures-to-support-intrahospital-exclusive-breastfeeding-evidence-of-systematic-reviews
#15
Kelly Pereira Coca, Vânia Lopes Pinto, Flavia Westphal, Pâmilla Nayara Alves Mania, Ana Cristina Freitas de Vilhena Abrão
OBJECTIVE: To identify the main recommendations found in systematic reviews regarding exclusive breastfeeding protective factors. DATA SOURCE: Integrative review based on the guiding question: What evidence is found in literature regarding the protective factors of exclusive breastfeeding during the intrahospital period? A search was conducted in the Cochrane Library, PubMed/MEDLINE and LILACS database using the keyword "Breast Feeding" and the word "Breastfeeding"...
April 23, 2018: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://www.readbyqxmd.com/read/29694464/effects-of-a-physical-therapy-protocol-in-patients-with-chronic-migraine-and-temporomandibular-disorders-a-randomized-single-blinded-clinical-trial
#16
Miriam Garrigós-Pedrón, Roy La Touche, Pablo Navarro-Desentre, Manuel Gracia-Naya, Eva Segura-Ortí
AIMS: To investigate the effects of adding orofacial treatment to cervical physical therapy in patients with chronic migraine and temporomandibular disorders (TMD). METHODS: A total of 45 participants with chronic migraine and TMD aged 18 to 65 years were randomized into two groups: a cervical group (CG) and a cervical and orofacial group (COG). Both groups continued their medication regimens for migraine treatment and received physical therapy. The CG received physical therapy only in the cervical region, and the COG received physical therapy in both the cervical and orofacial regions...
April 2018: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/29673859/orofacial-neuropathic-pain-reduces-spontaneous-burrowing-behavior-in-rats
#17
K Deseure, G Hans
It was recently reported that spontaneous burrowing behavior is decreased after tibial nerve transection, spinal nerve transection and partial sciatic nerve ligation. It was proposed that spontaneous burrowing could be used as a measure of the impact of neuropathic pain after peripheral nerve injury. It has remained unclear whether the reduction in burrowing behavior is caused directly by pain or hypersensitivity in the affected limbs, making it more difficult to perform burrowing, or by a pain induced decrease in the general wellbeing, thus reducing the motivation to burrow...
April 16, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29660457/a-lectin-fraction-from-green-seaweed-caulerpa-cupressoides-inhibits-inflammatory-nociception-in-the-temporomandibular-joint-of-rats-dependent-from-peripheral-mechanisms
#18
Renata Line da Conceição Rivanor, Danielle Rocha Do Val, Natássia Albuquerque Ribeiro, Felipe Dantas Silveira, Ellen Lima de Assis, Álvaro Xavier Franco, Lorena Vasconcelos Vieira, Ismael Nilo Lino de Queiroz, Hellíada Vasconcelos Chaves, Mirna Marques Bezerra, Norma Maria Barros Benevides
Temporomandibular disorders are the second most common cause of orofacial pain mediated by inflammatory compounds, which in many cases leads to chronic orofacial pain. This study assessed the antinociceptive and anti-inflammatory effects of a lectin from the green seaweed Caulerpa cupressoides (CcL) on hypernociception inflammatory in TMJ of rats and investigated the involvement of different mechanisms. Rats received i.v. CcL 30 min prior to injection of flogistic agentes or 0.9% saline into the left TMJ...
April 13, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29652011/quest-for-haller-cells-a-digital-orthopantomography-study
#19
Kavitaa Nedunchezhian, Nalini Aswath, A Amudhan
Aims: Haller Cells refer to the ethmoidal pneumatization and are the extensions of anterior ethmoid sinus into the floor of the orbit and superior aspect of the maxillary sinus, basically an anatomic variation. They may be associated with orofacial pain, sinusitis, nasal obstruction, impaired nasal breathing, headache, chronic cough, and mucocele. The aim of the present study was to identify, determine the prevalence and characteristics of Haller's cells on Digital orthopantomographs in patient's reporting to a dental institution in Chennai...
March 2018: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/29650024/vglut1-or-vglut2-mrna-positive-neurons-in-spinal-trigeminal-nucleus-provide-collateral-projections-to-both-the-thalamus-and-the-parabrachial-nucleus-in-rats
#20
Chun-Kui Zhang, Zhi-Hong Li, Yu Qiao, Ting Zhang, Ya-Cheng Lu, Tao Chen, Yu-Lin Dong, Yun-Qing Li, Jin-Lian Li
The trigemino-thalamic (T-T) and trigemino-parabrachial (T-P) pathways are strongly implicated in the sensory-discriminative and affective/emotional aspects of orofacial pain, respectively. These T-T and T-P projection fibers originate from the spinal trigeminal nucleus (Vsp). We previously determined that many vesicular glutamate transporter (VGLUT1 and/or VGLUT2) mRNA-positive neurons were distributed in the Vsp of the adult rat, and most of these neurons sent their axons to the thalamus or cerebellum. However, whether VGLUT1 or VGLUT2 mRNA-positive projection neurons exist that send their axons to both the thalamus and the parabrachial nucleus (PBN) has not been reported...
April 12, 2018: Molecular Brain
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