Elisa Micalizzi, Alice Ballerini, Giada Giovannini, Maria Cristina Cioclu, Simona Scolastico, Matteo Pugnaghi, Niccolò Orlandi, Marcella Malagoli, Maurilio Genovese, Alessandra Todeschini, Leandra Giunta, Flavio Villani, Stefano Meletti, Anna Elisabetta Vaudano
OBJECTIVE: Ictal central apnea (ICA) is a frequent correlate of focal seizures, particularly in temporal lobe epilepsy (TLE), and regarded as a potential electroclinical biomarker of sudden unexpected death in epilepsy (SUDEP). Aims of this study are to investigate morphometric changes of subcortical structures in ICA patients and to find neuroimaging biomarkers of ICA in patients with focal epilepsy. METHODS: We prospectively recruited focal epilepsy patients with recorded seizures during a video-EEG long-term monitoring with cardiorespiratory polygraphic recordings from April 2020 to September 2022...
November 7, 2023: Annals of Clinical and Translational Neurology