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Lumbar disk herniation

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https://www.readbyqxmd.com/read/29775946/il-9-exhibits-elevated-expression-in-osteonecrosis-of-femoral-head-patients-and-promotes-cartilage-degradation-through-activation-of-jak-stat-signaling-in-vitro
#1
Wei Geng, Wen Zhang, Jinzhu Ma
Osteonecrosis of the femoral head (ONFH) often causes severe symptoms in young people and limits the mobility of the hip joint. Interleukin-9 (IL-9) is a multi-functional inflammatory factor that participates in lumbar disk herniation and arthritis and has been reported in many studies. However, the correlation between IL-9 and ONFH is unclear. The present study aimed to determine the role of IL-9 in the pathogenetic mechanism of osteonecrosis. To assess IL-9 expression in ONFH and femoral neck fracture patients, cartilage tissue was examined through western blot analysis and immunohistochemistry...
May 15, 2018: International Immunopharmacology
https://www.readbyqxmd.com/read/29772868/-significance-of-cell-autophagy-in-resorption-of-lumbar-disc-herniation
#2
REVIEW
Zhi-Jun Diao, Hong Jiang, Jin-Tao Liu
As a self-protective mechanism of cells, autophagy of cells can maintain cell stability by degrading self-aging substances, and it can be highly induced. The ability of autophagy to degraded cells will decrease with age. The resorption phenomenon after lumbar disc herniation is one of the effective mechanisms in conservative treatment of lumbar disc herniation. The degenerative lesion of intervertebral disc is one of the main reasons of lumbar disc herniation. Cell autophagy is extensive participation in the degeneration of lumbar intervertebral disc, delaying the occurrence of degenerative disease...
April 25, 2018: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29751850/comparison-between-transcutaneous-electrical-nerve-stimulation-and-stabilization-exercises-in-fatigue-and-transversus-abdominis-activation-in-patients-with-lumbar-disk-herniation-a-randomized-study
#3
Luiz Armando Vidal Ramos, Bianca Callegari, Fábio Jorge Renovato França, Maurício Oliveira Magalhães, Thomaz Nogueira Burke, Ana Paula de Moura Campos Carvalho E Silva, Gabriel Peixoto Leão Almeida, Josielli Comachio, Amélia Pasqual Marques
OBJECTIVE: The purpose of this study was to compare transcutaneous electrical nerve stimulation (TENS) and stabilization exercises in an attempt to prevent fatigue and improve muscle activation in patients with lumbar disk herniation associated with low back pain. METHODS: This study involved 29 patients (age range 25-58 years) randomized into 2 groups: the segmental stabilization group (n = 15), who received stabilization exercises on the transversus abdominis (TrA) and lumbar multifidus muscles; and the TENS group (n = 14), who received electrotherapy...
May 2018: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/29730458/annular-closure-in-lumbar-microdiskectomy-for-prevention-of-reherniation-a-randomized-clinical-trial
#4
Claudius Thomé, Peter Douglas Klassen, Gerrit J Bouma, Adisa Kursumovic, Javier Fandino, Martin Barth, Mark Arts, Wimar van den Brink, Richard Bostelmann, Aldemar Hegewald, Volkmar Heidecke, Peter Vajkoczy, Susanne Fröhlich, Jasper Wolfs, Richard Assaker, Erik Van de Kelft, Hans-Peter Köhler, Senol Jadik, Sandro Eustacchio, Robert Hes, Frederic Martens
BACKGROUND CONTEXT: Patients with large annular defects following lumbar diskectomy for disk herniation are at high risk for symptomatic recurrence and reoperation. PURPOSE: To determine whether a bone-anchored annular closure device in addition to lumbar microdiskectomy resulted in lower reherniation and reoperation rates plus increased overall success compared to lumbar microdiskectomy alone. DESIGN: Multicenter, randomized superiority study...
May 3, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29707090/recurrence-is-associated-with-body-mass-index-in-patients-undergoing-a-single-level-lumbar-disc-herniation-surgery
#5
George Fotakopoulos, Demosthenes Makris, Polikceni Kotlia, Christos Tzerefos, Kostas Fountas
Background: The aim of the study was to assess the body mass index (BMI) and other risk factors associated with lumbar disc herniation (LDH) and clinical outcomes, in patients who undergo surgery for single-level LDH. Methods: This was a retrospective cohort study, affecting patients that underwent surgery for single-level LDH attending our hospital between July 2009 and January 2016. The mean follow-up period was 3.5 years (1 - 8 years). To maintain adequately sized groups for analysis, level L2-L3 and L3-L4 herniations were grouped as upper disc levels (group A) and level L4-L5 (group B) and L5-S1 (group C) herniations were analyzed individually...
June 2018: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/29684923/percutaneous-endoscopic-interlaminar-unilateral-ventral-dural-approach-for-symptomatic-bilateral-l5-s1-herniated-nucleus-pulposus-technical-note
#6
Sung Ho Choi, Nitin Maruti Adsul, Hyeun Sung Kim, Ki Joon Kim, Jeong Hoon Kim, Sung Kyun Chung, Jeong Hoon Choi, Jee Soo Jang, Il Tae Jang, Seong Hoon Oh
BACKGROUND:  Percutaneous endoscopic lumbar diskectomy is a good treatment modality for lumbar disk herniation. However, when a patient complains of bilateral lower limb radicular pain with severe disk protrusion at the L5-S1 level, the transforaminal approach is often unable to resolve both lesions owing to anatomical limitations. It is also very difficult to resolve both lesions in an ipsilateral direction using the percutaneous interlaminar approach. We report our surgical technique and clinical results using a ventral dural approach of percutaneous endoscopic interlaminar lumbar diskectomy for L5-S1 herniated nucleus pulposus (HNP) in patients with bilateral radiculopathy due to a severe disk protrusion...
April 23, 2018: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/29649852/outcome-predictors-of-the-transforaminal-endoscopic-spine-system-technique-for-single-level-lumbar-disk-herniation
#7
Jinchun Wu, Bin Yu, Bin He, Gang Liu, Jidong Ju, Jianguang Zhu
BACKGROUND:  Endoscopic spine surgery has become increasingly popular. However, no study has researched the predictive factors for different outcomes. This study is the first to evaluate the outcome predictors of the transforaminal endoscopic spine system (TESSYS) technique for lumbar disk herniation (LDH). METHODS:  We performed a prospective study of 80 patients meeting the inclusion criteria who underwent TESSYS for LDH. Clinical outcomes were assessed by the visual analog scale (VAS), the Oswestry Disability Index (ODI), and the modified MacNab criteria...
April 12, 2018: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/29628718/preliminary-results-of-lumbar-disk-herniation-surgery-by-endoscopic-destandau-method
#8
Keyvan Mostofi, Reza Karimi Khouzani
Background: The incidence of Disc herniation is about 2-3% of population. Each year 300,000 procedures performed in USA. The aim of this paper is to describe the utility of endoscopic procedure in treatment of lumbar disc herniation. Methods: We operated 359 patients from September 2013 to December 2016 for lumbar disk herniation by Endoscopic DESTANDAU method (EDM). The average length of surgery was 47 min. We operated 211 male and 148 female patients. In average, patients had pain for 4...
March 2018: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/29582973/transforaminal-percutaneous-endoscopic-lumbar-discectomy-outcome-and-complications-in-270-cases
#9
Leonello Tacconi, Sara Baldo, Giorgio Merci, Gerardo Serra
BACKGROUND: The endoscopic approach has been introduced in the clinical practice in 1980 with the aim to remove the pro- lapsed disk and free the compressed nerve using the least disruptive surgical technique, assuring in the same time, the resolution of the symptoms and a faster return back to normal life activity. Over the years, thanks to an extraordinary technical improvement either in terms of quality of images and development of many dif- ferent tailored instrumentations there has been a huge spreading of the endoscope use across the different surgical fields...
March 26, 2018: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/29528877/genetic-variant-of-socs3-gene-is-functionally-associated-with-lumbar-adolescent-idiopathic-scoliosis
#10
Jun Qiao, Lingyan Xiao, Leilei Xu, Bangping Qian, Zezhang Zhu, Yong Qiu
STUDY DESIGN: This is a genetic association study. OBJECTIVE: To investigate association between suppressor of cytokine signaling-3 (SOCS3) gene polymorphisms and the onset and progression of lumbar adolescent idiopathic scoliosis (AIS) and to further clarify its role in the regulation of SOCS3 expression in AIS patients. SUMMARY OF BACKGROUND DATA: Some studies showed that muscle development imbalance may be responsible for onset and progression of lumbar AIS...
April 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29442136/spontaneous-regression-of-a-large-calcified-thoracic-disk-extrusion
#11
Hayley Oligane, Jean Rongo, Vikas Agarwal, Barton F Branstetter
Although spontaneous regression of herniated disk material has been reported in the lumbar and cervical spine, reports of complete spontaneous regression of calcified thoracic disk herniations are exceedingly rare. In symptomatic patients, surgery is typically the treatment of choice; however, conservative therapy with surveillance may allow time for spontaneous resolution and potentially avoid high-risk surgery. We report a 40-year-old woman with complete spontaneous resolution of a large calcified thoracic disk extrusion with conservative management over an 8-month period...
February 13, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29384882/tubular-microscopes-discectomy-versus-conventional-microdiscectomy-for-treating-lumbar-disk-herniation-systematic-review-and-meta-analysis
#12
REVIEW
Xianbo Li, Hengrui Chang, Xianzhong Meng
BACKGROUND: The application of tubular microscopes discectomy (TMD) was supposed to have similar or better results than conventional microdiscectomy (CMD). However, this conclusion had not been verified by sufficient evidence. Therefore, the focus of this meta-analysis was to assess the efficiency, safety, and clinical outcome of these 2 surgical procedures for treating lumbar disk herniation (LDH). METHODS: PubMed, Embase, and Cochrane Collaboration Central databases were searched for studies which compared the results of TMD and CMD for the treatment of LDH up to July 2017...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29369138/lumbar-degenerative-disease-with-intervertebral-disk-herniation
#13
(no author information available yet)
No abstract text is available yet for this article.
January 2018: Orthopaedic Nursing
https://www.readbyqxmd.com/read/29369137/lumbar-degenerative-disease-with-intervertebral-disk-herniation
#14
Patrick Graham
No abstract text is available yet for this article.
January 2018: Orthopaedic Nursing
https://www.readbyqxmd.com/read/29329586/il-33-st2-signaling-contributes-to-radicular-pain-by-modulating-mapk-and-nf-%C3%AE%C2%BAb-activation-and-inflammatory-mediator-expression-in-the-spinal-cord-in-rat-models-of-noncompressive-lumber-disk-herniation
#15
Si-Jian Huang, Jian-Qin Yan, Hui Luo, Lu-Yao Zhou, Jian-Gang Luo
BACKGROUND: Immune and inflammatory responses occurring in the spinal cord play a pivotal role in the progression of radicular pain caused by intervertebral disk herniation. Interleukin-33 (IL-33) orchestrates inflammatory responses in a wide range of inflammatory and autoimmune disorders of the nervous system. Thus, the purpose of this study is to investigate the expression of IL-33 and its receptor ST2 in the dorsal spinal cord and to elucidate whether the inhibition of spinal IL-33 expression significantly attenuates pain-related behaviors in rat models of noncompressive lumbar disc herniation...
January 12, 2018: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29241273/transforaminal-percutaneous-endoscopic-lumbar-diskectomy-for-downmigrated-disk-herniations-lever-up-rotate-and-tilt-technique
#16
Sang Soo Eun, Sang-Ho Lee, H Yener Erken
BACKGROUND AND STUDY AIMS:  Although transforaminal percutaneous endoscopic lumbar diskectomy (PELD) offers certain advantages in the treatment of disk herniations, it used to be limited to nonmigrated or low-migrated herniations. With improvements in endoscopic spinal surgery, the range of indications for PELD has expanded. Various techniques including transforaminal and interlaminar approaches for migrated disk herniations are described in the literature. This study describes a transforaminal PELD approach to address downmigrated intracanal soft disk herniations effectively using the lever-up, rotate, and tilt technique...
March 2018: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/29241269/comparison-of-percutaneous-endoscopic-lumbar-diskectomy-and-open-lumbar-microdiskectomy-for-recurrent-lumbar-disk-herniation
#17
Jung-Sup Lee, Hyeun-Sung Kim, Yong-Hun Pee, Jee-Soo Jang, Il-Tae Jang
No abstract text is available yet for this article.
December 14, 2017: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/29114720/spontaneous-disappearance-of-large-lumbar-disk-herniation
#18
Sheng Gao, Xiaopeng Geng, Qingmin Fang
No abstract text is available yet for this article.
January 1, 2018: JAMA Neurology
https://www.readbyqxmd.com/read/29106681/common-missense-variant-of-scn9a-gene-is-associated-with-pain-intensity-in-patients-with-chronic-pain-from-disc-herniation
#19
Mateusz Kurzawski, Marcin Rut, Violetta Dziedziejko, Krzysztof Safranow, Anna Machoy-Mokrzynska, Marek Drozdzik, Monika Bialecka
Objective: Lumbar intervertebral disk herniation (LDH) is considered one of the major risk factors for lower back pain, mainly caused by irritation of a spinal nerve or its root. One of the genes related to pain perception is SCN9A, which encodes the voltage gated sodium channel NaV1.7, a key molecule involved in peripheral pain processing. It had been presented before that a common polymorphism within SCN9A (rs6746030: G > A, R1150W) might influence nociception in the general population...
May 1, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29080003/percutaneous-posterolateral-approach-for-the-simulation-of-a-far-lateral-disc-herniation-in-an-ovine-model
#20
Stefan Schwan, Christopher Ludtka, Ingo Wiesner, Andre Baerthel, Andrea Friedmann, Felix Göhre
PURPOSE: This work describes a minimally invasive damage model for ovine lumbar discs via partial nucleotomy using a posterolateral approach. METHODS: Two cadavers were dissected to analyze the percutaneous corridor. Subsequently, 28 ovine had their annulus fibrosus punctured via awl penetration under fluoroscopic control and nucleus pulposus tissue removed via rongeur. Efficacy was assessed by animal morbidity, ease of access to T12-S1 disc spaces, and production of a mechanical injury as verified by discography, radiography, and histology...
January 2018: European Spine Journal
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