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Lumbar disk herniation

Jun Qiao, Lingyan Xiao, Leilei Xu, Bangping Qian, Zezhang Zhu, Yong Qiu
STUDY DESIGN: This is a genetic association study. OBJECTIVE: To investigate association between suppressor of cytokine signaling-3 (SOCS3) gene polymorphisms and the onset and progression of lumbar adolescent idiopathic scoliosis (AIS) and to further clarify its role in the regulation of SOCS3 expression in AIS patients. SUMMARY OF BACKGROUND DATA: Some studies showed that muscle development imbalance may be responsible for onset and progression of lumbar AIS...
March 9, 2018: Clinical Spine Surgery
Hayley Oligane, Jean Rongo, Vikas Agarwal, Barton F Branstetter
Although spontaneous regression of herniated disk material has been reported in the lumbar and cervical spine, reports of complete spontaneous regression of calcified thoracic disk herniations are exceedingly rare. In symptomatic patients, surgery is typically the treatment of choice; however, conservative therapy with surveillance may allow time for spontaneous resolution and potentially avoid high-risk surgery. We report a 40-year-old woman with complete spontaneous resolution of a large calcified thoracic disk extrusion with conservative management over an 8-month period...
February 13, 2018: Skeletal Radiology
Xianbo Li, Hengrui Chang, Xianzhong Meng
BACKGROUND: The application of tubular microscopes discectomy (TMD) was supposed to have similar or better results than conventional microdiscectomy (CMD). However, this conclusion had not been verified by sufficient evidence. Therefore, the focus of this meta-analysis was to assess the efficiency, safety, and clinical outcome of these 2 surgical procedures for treating lumbar disk herniation (LDH). METHODS: PubMed, Embase, and Cochrane Collaboration Central databases were searched for studies which compared the results of TMD and CMD for the treatment of LDH up to July 2017...
February 2018: Medicine (Baltimore)
(no author information available yet)
No abstract text is available yet for this article.
January 2018: Orthopaedic Nursing
Patrick Graham
No abstract text is available yet for this article.
January 2018: Orthopaedic Nursing
Si-Jian Huang, Jian-Qin Yan, Hui Luo, Lu-Yao Zhou, Jian-Gang Luo
BACKGROUND: Immune and inflammatory responses occurring in the spinal cord play a pivotal role in the progression of radicular pain caused by intervertebral disk herniation. Interleukin-33 (IL-33) orchestrates inflammatory responses in a wide range of inflammatory and autoimmune disorders of the nervous system. Thus, the purpose of this study is to investigate the expression of IL-33 and its receptor ST2 in the dorsal spinal cord and to elucidate whether the inhibition of spinal IL-33 expression significantly attenuates pain-related behaviors in rat models of noncompressive lumbar disc herniation...
January 12, 2018: Journal of Neuroinflammation
Sang Soo Eun, Sang-Ho Lee, H Yener Erken
BACKGROUND AND STUDY AIMS:  Although transforaminal percutaneous endoscopic lumbar diskectomy (PELD) offers certain advantages in the treatment of disk herniations, it used to be limited to nonmigrated or low-migrated herniations. With improvements in endoscopic spinal surgery, the range of indications for PELD has expanded. Various techniques including transforaminal and interlaminar approaches for migrated disk herniations are described in the literature. This study describes a transforaminal PELD approach to address downmigrated intracanal soft disk herniations effectively using the lever-up, rotate, and tilt technique...
March 2018: Journal of Neurological Surgery. Part A, Central European Neurosurgery
Jung-Sup Lee, Hyeun-Sung Kim, Yong-Hun Pee, Jee-Soo Jang, Il-Tae Jang
No abstract text is available yet for this article.
December 14, 2017: Journal of Neurological Surgery. Part A, Central European Neurosurgery
Sheng Gao, Xiaopeng Geng, Qingmin Fang
No abstract text is available yet for this article.
November 6, 2017: JAMA Neurology
Mateusz Kurzawski, Marcin Rut, Violetta Dziedziejko, Krzysztof Safranow, Anna Machoy-Mokrzynska, Marek Drozdzik, Monika Bialecka
Objective: Lumbar intervertebral disk herniation (LDH) is considered one of the major risk factors for lower back pain, mainly caused by irritation of a spinal nerve or its root. One of the genes related to pain perception is SCN9A, which encodes the voltage gated sodium channel NaV1.7, a key molecule involved in peripheral pain processing. It had been presented before that a common polymorphism within SCN9A (rs6746030: G > A, R1150W) might influence nociception in the general population...
November 2, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
Stefan Schwan, Christopher Ludtka, Ingo Wiesner, Andre Baerthel, Andrea Friedmann, Felix Göhre
PURPOSE: This work describes a minimally invasive damage model for ovine lumbar discs via partial nucleotomy using a posterolateral approach. METHODS: Two cadavers were dissected to analyze the percutaneous corridor. Subsequently, 28 ovine had their annulus fibrosus punctured via awl penetration under fluoroscopic control and nucleus pulposus tissue removed via rongeur. Efficacy was assessed by animal morbidity, ease of access to T12-S1 disc spaces, and production of a mechanical injury as verified by discography, radiography, and histology...
January 2018: European Spine Journal
Jin-Sang Kil, Jong-Tae Park
Lumbar disk herniation is common. Because of the posterior longitudinal ligament, migration usually occurs into the ventral epidural space. Rarely, fragments migrate into the dorsal epidural space. A 57-year-old man presented with lower back pain and weakness on right hip flexion and right knee flexion. He had lower back pain 1 day previously and received a transforaminal epidural block at a local hospital. The next day, he reported weakness of the right lower extremity. Lumbar spine magnetic resonance imaging revealed a dorsal epidural lesion with compression of the thecal sac at L2-3...
September 2017: Korean Journal of Spine
Kurt M Mohty, Divneet Mandair, Brent Munroe, Deborah Baldemor
Physicians are often faced with managing difficult conditions such as chronic lower back pain. Intervertebral disk herniation typically occurs horizontally, leading to impingement of the spinal cord which can potentially cause radicular symptoms or other spinal cord pathologies; however, disk herniations can also occur vertically and extend through the endplate of an adjacent cranial or caudal vertebra: a phenomenon known as a Schmorl's node. Although Schmorl's nodes can be seen in many asymptomatic individuals, they can be a cause of degenerative disk disease and low back pain...
July 21, 2017: Curēus
Maribel R Gomes, Alexandre M P Sousa, Roberto J A Couto, Marco M B Oliveira, João L M Moura, Carlos A Vilela
Malignant peripheral nerve sheath tumors (MPNST) are very rare and are frequently localized in the buttocks, thigh, arm, or paraspinal region; one variant is the malignant Triton tumor, with rhabdomyosarcomatous differentiation. The authors present a challenging differential diagnosis of a sciatic pain and foot drop in a woman with history of lumbar disk herniation, which was found to be caused by a Triton tumor of the sciatic nerve. She underwent surgical excision, followed by radiation and chemotherapy. Malignant Triton tumor cases have rarely been described and reported in the literature...
June 2017: Revista Brasileira de Ortopedia
Doaa Abdelmohsen Abou-Elroos, Mirvat Abd El-Hameed El-Toukhy, Ghada Sanad Nageeb, Essam Abdelhameed Dawood, Safwat Abouhashem
STUDY DESIGN: Randomized controlled trial. PURPOSE: We compared the disability and functional outcome after conservative treatment with prolonged physiotherapy versus early surgical intervention in patients with lumbar disk herniation. OVERVIEW OF LITERATURE: Lumbar disk herniation is one of the most common causes of job-related disability in individuals less than 45 years old. Conservative treatment is the initial pathway for the majority of patients but the duration of conservative treatment remains debatable and the adverse effects of prolonged conservative treatment are still unclear...
August 2017: Asian Spine Journal
Evgenii Belykh, Andrey A Kalinin, Arpan A Patel, Eric J Miller, Michael A Bohl, Ivan A Stepanov, Liudmila A Bardonova, Talgat Kerimbaev, Anton O Asantsev, Morgan B Giers, Mark C Preul, Vadim A Byvaltsev
PURPOSE: To assess the utility of apparent diffusion coefficient (ADC) maps for the assessment of patients with advanced degenerative lumbar spine disease and describe characteristic features of ADC maps in various degenerative lumbar spinal conditions. METHODS: T1-weighted, T2-weighted and diffusion weighted (DWI) MR images of 100 consecutive patients admitted to the spinal surgery service were assessed. ADC maps were generated from DWI images using Osyrix software...
2017: PloS One
M Dobran, D Brancorsini, M Della Costanza, V Liverotti, F Mancini, D Nasi, M Iacoangeli, M Scerrati
BACKGROUND: To limit epidural fibrosis and prevent scar formation/nerve tethering that may contribute to chronic postoperative pain; some surgeons have utilized epidural autologous fat grafts following lumbar microdiscectomy. METHODS: We investigated the correlation between post-microdiscectomy epidural scarring [including select magnetic resonance imaging (MRI) studies] and clinical outcomes in 36 patients operated for symptomatic. MRI documented L4-L5 and L5-S1 disk herniations with (18 patients) and without (18 patient) the application of free fat grafts...
2017: Surgical Neurology International
Oluwaseun O Akinduro, Panagiotis Kerezoudis, Mohammed Ali Alvi, Jang W Yoon, Jamachi Eluchie, M Hassan Murad, Zhen Wang, Selby G Chen, Mohamad Bydon
INTRODUCTION: Extraforaminal disk herniation (EDH) accounts for 3%-11% of all disk herniations. Despite the heterogeneity of spinal procedures, there is a paucity of literature comparing the outcomes from different surgical approaches. METHODS: We performed a systematic review and meta-analysis of available literature on EDHs. We compared patients undergoing open surgery (OS) with those undergoing minimally invasive surgery (MIS) approaches, including tubular microscopic, percutaneous endoscopic, and microendoscopic...
December 2017: World Neurosurgery
Hee-Sup Moon, Yong-Hyun Hwang, Hee-Chun Lee, Jae-Hoon Lee
The present study aimed to investigate the technical feasibility of percutaneous endoscopic mini-hemilaminectomy via a uniportal approach, and to evaluate the possibility of decompression and endoscopic examination of the thoracic and lumbar spinal canals in small dogs during such procedures. Fresh canine cadavers of mixed-breed dogs (n=7) were used in this study. Following injection of a barium and agarose mixture (BA-gel) to stimulate intervertebral disc herniation, percutaneous endoscopic mini-hemilaminectomy was performed using a lateral approach to the thoracic and lumbar vertebrae...
September 12, 2017: Journal of Veterinary Medical Science
Huadong Wang, Zhonghai Li, Chunli Zhang, Weisheng Zhang, Li Li, Jidong Guo, Wenwen Wu, Shuxun Hou
The aim of this study was to analyze the correlation between high-intensity zone (HIZ) on magnetic resonance imaging (MRI) of a lumbar disc and positive pain response assessed by discography for the diagnosis and treatment of discogenic low back pain (LBP). Thirty-seven patients aged 21 to 59 years with chronic LBP but without any neurological symptoms or lumbar disc herniation who underwent MRI and subsequent discography were included in this study. During discography, concordant pain was regarded as positive, whereas discordant pain and no pain were regarded as negative...
July 2017: Medicine (Baltimore)
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