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https://www.readbyqxmd.com/read/29350272/endoscopic-endonasal-approach-for-trigeminal-schwannomas-our-experience-of-39-patients-in-10%C3%A2-years
#1
Lu Yang, Li Hu, Weidong Zhao, Huankang Zhang, Quan Liu, Dehui Wang
BACKGROUND: The anatomical locations involved in trigeminal schwannomas (TSs) are quite complex. The endoscopic endonasal approach provides a minimal damage access corridor to both anterior and middle skull base for surgery. Given the nerve function recovery and postoperative neurological deterioration varied in different reports, the author demonstrates his surgery tips and the functional outcomes under endoscopic surgery in one single institution. METHODS: A retrospective review of patients with TSs was undertaken to assess the outcome of endoscopic surgery from 2006 to 2016...
January 19, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29345402/association-of-long-term-glycaemic-control-on-tear-break-up-times-and-dry-eye-symptoms-in-chinese-patients-with-type-2-diabetes
#2
Andre Ma, Martin Sy Mak, Kendrick Co Shih, Claudia Ky Tsui, Rachel Ky Cheung, Sherman Haynam Lee, Hubert Leung, Joyce Ns Leung, Jason Th Leung, Marco Zhenji Van-Boswell, Michael Tl Wong, Alex Lap-Ki Ng, Chi-Ho Lee, Vishal Jhanji, Louis Tong
Importance Diabetes mellitus is known to be associated with dry eye syndrome (DES), but the effects of long term glycaemic control on tear film metrics and dry eye symptoms are not known in the Chinese population. BACKGROUND: To evaluate tear film stability and dry eye symptoms and their associations with systemic risk factors in Chinese patients with type 2 diabetes (T2DM) Design Cross-sectional study set at the Lo Fong Siu Po Eye Centre (Grantham Hospital), Hong Kong.
January 18, 2018: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/29344500/pilot-study-of-a-large-eye-surgically-induced-dry-eye-rabbit-model-by-selective-removal-of-the-harderian-lacrimal-and-meibomian-glands
#3
Arthur S Polans, Jonathan F McAnulty, Paul O Phelps, Soesiawati R Darjatmoko, Christopher K Burris, Daniel M Albert
Background/Aims: Establish a reliable rabbit dry eye (DE) model. Methods: An interventional cohort study surgically removing glands contributing to the tear film. Eight rabbits were studied after removal of left lacrimal, Harderian, or both glands. Additional rabbits had Meibomian glands in the left eye thermally obstructed. All were followed for 10 weeks with phenol red thread (PRT) and slit-lamp examination with 2% fluorescein. We assessed corneal sensitivity using a Cochet-Bonnet esthesiometer...
December 2017: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29344480/primary-conjunctival-tuberculosis-presenting-as-dry-eye-a-rare-case-report-and-review-of-the-literature
#4
Rupinder Kaur Brar, Ashok Singh, Archana Hemant Deshpande, Chitrawati Bal Gargade, Sujit Das
Primary conjunctival tuberculosis is very rare in the developed countries. In an endemic country like India, it should be considered in the differential diagnosis of any unusual conjunctival lesion with unilaterality, chronicity, and nonresolution of symptoms after steroid use. We present the case of a 52-year-old female who presented with unilateral itching and blurring of vision for 20 days. There were irregular nodular elevated areas with shrinkage of the lower palpebral conjunctiva. A biopsy of the lesion revealed necrotizing epithelioid cell granulomas along with Langhans type of giant cells...
November 2017: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29340652/pain-sensitivity-associated-with-the-length-of-the-maximum-interblink-period
#5
Wing Li, Meng C Lin
Purpose: Pain sensitivity has been identified as a factor that affects how individuals answer dry eye questionnaires, but it is unknown how it affects ocular discomfort. This study used the time that individuals could refrain from blinking as an indicator of ocular discomfort and set out to determine whether it was related to pain sensitivity, while adjusting for ocular surface conditions. Methods: Subjects first completed the Pain Sensitivity Questionnaire to quantify pain sensitivity levels...
January 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29338780/coping-with-dry-eyes-a-qualitative-approach
#6
Sharon Yeo, Louis Tong
BACKGROUND: Dry eye is a common problem that affects many people worldwide, reducing quality of life and impacting daily activities. A qualitative approach often used in medicine and other disciplines is used to evaluate how people with dry eye cope with this impact. METHODS: Six focus group sessions were conducted at the Singapore National Eye Centre (SNEC), premises of an eye research institute. These focus groups consist of a spectrum of dry eye sufferers (30 women, 8 men, aged 61 ± 11...
January 16, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29337016/tear-instability-importance-mechanisms-validity-and-reliability-of-assessment
#7
Charles W Mcmonnies
PURPOSE: To examine the factors which contribute to tear stability and the validity and reliability of methods used for assessing tear break up time which is a core part of an examination of tear stability in dry eye patients. METHODS: A review of publications which are relevant to tear stability and its assessment. RESULTS: Tear break up time may be more invasive than intended if difficulty avoiding blinking during assessment results in reflex tearing...
January 11, 2018: Journal of Optometry
https://www.readbyqxmd.com/read/29337006/relation-between-dietary-essential-fatty-acid-intake-and-dry-eye-disease-and-meibomian-gland-dysfunction-in-postmenopausal-women
#8
Jillian F Ziemanski, Lynn R Wolters, Lisa Jones-Jordan, Jason J Nichols, Kelly K Nichols
PURPOSE: To evaluate the relationship between omega-3 (n-3) and omega-6 (n-6) fatty acids with dry eye disease (DED) and meibomian gland dysfunction (MGD) DESIGN: Cross-sectional study METHODS: Postmenopausal women (n=439) underwent a clinical evaluation and completed the Vio Food Frequency Questionnaire to estimate their dietary intake of n-3s and n-6s. Subjects were categorized into two binary classifications based upon whether or not they had (1) DED and (2) MGD. Mean intake of dietary fatty acids were compared with two-sample t-tests...
January 11, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29336696/controlled-adverse-environment-chambers-in-dry-eye-research
#9
Margarita Calonge, Marc Labetoulle, Elisabeth M Messmer, Sunil Shah, Yonca A Akova, Kostas G Boboridis, Jesús Merayo-Lloves, Pasquale Aragona, José Benítez-Del-Castillo, Gerd Geerling, Maurizio Rolando, Christophe Baudouin
Dry eye disease (DED) is a common condition with signs and symptoms that vary depending on a wide range of environmental factors to which people are exposed in their daily lives. Factors such as variable temperature, airflow velocity, relative humidity, seasonality, and pollutants can alter the rate of tear film evaporation, improving or exacerbating symptoms of DED. Results from currently available clinical tests do not always correlate well with patient-reported symptoms, and the continually changing environment and variability in DED symptoms present challenges for the design and conduct of clinical trials...
January 16, 2018: Current Eye Research
https://www.readbyqxmd.com/read/29336627/clinical-severity-classification-using-automated-conjunctival-hyperemia-analysis-software-in-patients-with-superior-limbic-keratoconjunctivitis
#10
Junki Kurita, Jun Shoji, Noriko Inada, Tsuyoshi Yoneda, Tamaki Sumi, Masahiko Kobayashi, Yasuhiro Hoshikawa, Atsuki Fukushima, Satoru Yamagami
PURPOSE: Digitization of clinical observation is necessary for assessing the severity of superior limbic keratoconjunctivitis (SLK). This study aimed to use a novel quantitative marker to examine hyperemia in patients with SLK. MATERIALS AND METHODS: We included six eyes of six patients with both dry eye disease and SLK (SLK group) and eight eyes of eight patients with Sjögren syndrome (SS group). We simultaneously obtained the objective finding scores by using slit-lamp examination and calculated the superior hyperemia index (SHI) with an automated conjunctival hyperemia analysis software by using photographs of the anterior segment...
January 16, 2018: Current Eye Research
https://www.readbyqxmd.com/read/29335106/preoperative-optimization-of-ocular-surface-disease-before-cataract-surgery
#11
REVIEW
Jasmine Chuang, Kendrick Co Shih, Tommy C Chan, Kelvin H Wan, Vishal Jhanji, Louis Tong
An impaired ocular surface adversely affects preoperative planning for cataract surgery, including intraocular lens (IOL) calculations, toric IOL axis and magnitude estimates, keratometry, and topography measurements. It also increases surgical difficulty. We performed a review to evaluate the connection between cataract surgery and dry eye and to determine the best management for these patients. Of the 16 papers included in this review, 6 were randomized controlled trials. Cataract surgery was shown to worsen ocular parameters and aggravate dry-eye disease...
December 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29334519/the-most-common-causes-of-eye-pain-at-2-tertiary-ophthalmology-and-neurology-clinics
#12
Randy C Bowen, Jan N Koeppel, Chance D Christensen, Karisa B Snow, Junjie Ma, Bradley J Katz, Howard R Krauss, Klara Landau, Judith E A Warner, Alison V Crum, Dominik Straumann, Kathleen B Digre
BACKGROUND: Eye pain is a common complaint, but no previous studies have determined the most common causes of this presenting symptom. Our objective was to determine the most common causes of eye pain in 2 ophthalmology and neurology departments at academic medical centers. METHODS: This was a retrospective cross-sectional analysis and chart review at the departments of ophthalmology and neurology at the University Hospital Zurich (USZ), University of Zürich, Switzerland, and the University of Utah (UU), USA...
January 12, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29326852/unusual-course-of-crystalline-keratopathy-in-a-patient-with-graft-versus-host-disease
#13
Başak Bostancı, Yonca Aydın Akova
We present a case of infectious crystalline keratopathy in a patient with Graft-versus-Host disease (GVHD) who developed satellite fungal keratitis. A 51-year-old man was referred for bilateral total persistent corneal epithelial defects with severe dry eye. Although persistent epithelial defect healed with medical therapy, he developed stromal keratitis with satellite lesions confirmed to be secondary to Candida albicans. After three months of antifungal treatment and debridement, improvement of the infiltrates was obtained...
December 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/29325546/development-and-evaluation-of-a-measure-of-patient-reported-symptoms-of-blepharitis
#14
Kamran Hosseini, Linda B Bourque, Ron D Hays
BACKGROUND: Blepharitis is an ocular surface disease and chronic ophthalmic condition. This paper reports on the development of psychometric evaluation of a patient-reported measure of blepharitis symptoms. METHODS: Self-reports of 13 blepharitis symptoms collected in a Phase 3 multi-site, randomized, double-masked, 4-arm parallel group, clinical trial of 907 individuals with blepharitis (mean age = 62, range: 19-93; 57% female) were analyzed. Symptoms asked about were: eyes that itch; eyes that burn; eyelids feel heavy or puffy; feel like something is in your eye; dry eyes; gritty eyes; irritated eyes; eyes that tear or water; crusty eyes; flaking from your eyelids; eyelids that are stuck together; red eyes or eyelids; and debris like pieces of skin or dandruff in your eyes...
January 11, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29320472/subjective-complaints-of-ocular-dryness-and-xerostomia-among-the-non-sj%C3%A3-gren-adult-population-of-lublin-region-poland
#15
Renata Chałas, Dorota Rykwa, Dominika Wróbel-Dudzińska, Tomasz Żarnowski
BACKGROUND Eye and mouth dryness are the most common symptoms reported during ophthalmological and dental examinations, and their frequency increases with age. In connection with population aging and the huge variety of factors and conditions that can induce this condition, it is becoming a serious and growing problem. The purpose of the present study was to determine whether ocular dryness and concomitant xerostomia is associated with particular systemic diseases. MATERIAL AND METHODS We enrolled 642 non-Sjögren patients referred for examination to the ophthalmology or dental clinic of Lublin region, Poland...
January 10, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29318025/feline-dry-eye-syndrome-of-presumed-neurogenic-origin-a-case-report
#16
Lionel Sebbag, Patricia A Pesavento, Sebastian E Carrasco, Christopher M Reilly, David J Maggs
Case summary: A 14-year-old female spayed Abyssinian cat, which about 1 year previously underwent thoracic limb amputation, radiotherapy and chemotherapy for an incompletely excised vaccine-related fibrosarcoma, was presented for evaluation of corneal opacity in the left eye (OS). The ocular surface of both eyes (OU) had a lackluster appearance and there was a stromal corneal ulcer OS. Results of corneal aesthesiometry, Schirmer tear test-1 (STT-1) and tear film breakup time revealed corneal hypoesthesia, and quantitative and qualitative tear film deficiency OU...
January 2018: JFMS Open Reports
https://www.readbyqxmd.com/read/29317327/sex-differences-in-clinical-characteristics-of-dry-eye-disease
#17
Jelle Vehof, Nicole Sillevis Smitt-Kamminga, Simone A Nibourg, Christopher J Hammond
PURPOSE: To investigate the role of sex on the symptomatology of DED and on the associations between symptoms and signs. METHODS: A cross-sectional study was used including 755 dry eye patients from the Groningen Longitudinal Sicca Study (GLOSSY cohort). Patient symptoms were assessed by the Ocular Surface Disease Index (OSDI) questionnaire and dry eye signs by the six most commonly used tests. Patients were divided in groups based on overall severity of signs and within these groups total and specific symptoms were compared by sex...
January 6, 2018: Ocular Surface
https://www.readbyqxmd.com/read/29313693/poloxamer-407-tpgs-mixed-micelles-as-promising-carriers-for-cyclosporine-ocular-delivery
#18
Maria Aurora Grimaudo, Silvia Pescina, Cristina Padula, Patrizia Santi, Angel Concheiro, Carmen Alvarez-Lorenzo, Sara Nicoli
Cyclosporine is an immunosuppressant agent approved for the treatment of dry eye disease and used off-label for other ocular pathologies. Its formulation and ocular bioavailability is a real challenge due to the large molecular weight (1.2 kDa), high lipophilicity and low water solubility. The aim of the work was to develop an aqueous micellar formulation for an efficient cyclosporine delivery to the ocular tissues, using a water soluble derivative of vitamin E (TPGS: d-alpha tocopheryl polyethylene glycol 1000 succinate) and a poloxamer (poloxamer 407) as excipients...
January 9, 2018: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/29310465/annals-express-predictive-role-of-tear-protein-expression-in-the-early-diagnosis-of-sj%C3%A3-gren-s-syndrome
#19
Piera Versura, Giuseppe Giannaccare, Gentiana Vukatana, Rita Mulè, Nazzarena Malavolta, Emilio Campos
BACKGROUND: The contribution of tear protein expression in patients with presumed diagnosis of Sjogren Syndrome (SS) is underestimated. We aimed to evaluate the role of tear proteins in the SS early diagnosis. METHODS: Charts from 110 patients suspected of SS were analyzed and the subsequent diagnosis retrieved. Subjective symptoms (Ocular Surface Disease Index, OSDI), tear film break-up time (TFBUT), Schirmer test, Jones test, Tear Clearance (TC), corneal (NEI score) and conjunctival staining (van Bjerstelveldt score), esthesiometry, cytology, tear protein analysis [total protein (TP) content, Lysozyme-C (LYS-C), Lactoferrin (LACTO), Lipocalin-1 (LIPOC-1) and Albumin (ALB)] were analyzed...
January 1, 2018: Annals of Clinical Biochemistry
https://www.readbyqxmd.com/read/29309836/ocular-complications-in-a-young-pediatric-population-following-bone-marrow-transplantation
#20
Mary Ellen Hoehn, Julie Calderwood, Edwin Gannon, Brittany Cook, Richard Rochester, Christine Hartford, Brandon Triplett, Anusha Sunkara, Guolian Kang, R Christopher Walton
PURPOSE: To investigate ocular complications associated with bone marrow transplant and associated continued maintenance therapy in a preschool population. METHODS: The medical records of patients <7 years of age were reviewed retrospectively. Patient charts were screened for cataract formation, dry eye, and other anterior and posterior segment disease. RESULTS: Of 270 cases reviewed, 91 met inclusion criteria. Mean age at diagnosis was 3...
January 5, 2018: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
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