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https://www.readbyqxmd.com/read/28211183/a-comparison-of-the-self-reported-dry-eye-practices-of-new-zealand-optometrists-and-ophthalmologists
#1
Ally L Xue, Laura E Downie, Susan E Ormonde, Jennifer P Craig
PURPOSE: The aim of this cross-sectional survey was to evaluate the self-reported clinical practices of New Zealand optometrists and ophthalmologists with respect to the diagnosis and management of dry eye disease. It also sought to compare these behaviours with the current research evidence base. METHODS: An anonymous survey was distributed electronically to New Zealand eye care clinicians (optometrists n = 614, ophthalmologists n = 113) to determine practitioner interest in dry eye disease, practice experience, practice modality, preferred diagnostic and management strategies, and information used to guide patient care...
March 2017: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/28207920/paper-based-microfluidic-system-for-tear-electrolyte-analysis
#2
Ali K Yetisen, Nan Jiang, Ali Tamayol, Guillermo U Ruiz-Esparza, Yu Shrike Zhang, Sofía Medina-Pando, Aditi Gupta, James S Wolffsohn, Haider Butt, Ali Khademhosseini, Seok-Hyun Yun
The analysis of tear constituents at point-of-care settings has a potential for early diagnosis of ocular disorders such as dry eye disease, low-cost screening, and surveillance of at-risk subjects. However, current minimally-invasive rapid tear analysis systems for point-of-care settings have been limited to assessment of osmolarity or inflammatory markers and cannot differentiate between dry eye subclassifications. Here, we demonstrate a portable microfluidic system that allows quantitative analysis of electrolytes in the tear fluid that is suited for point-of-care settings...
February 16, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28207431/successful-medical-management-of-presumptive-pythium-insidiosum-keratitis
#3
Muralidhar Ramappa, Ritu Nagpal, Savitri Sharma, Sunita Chaurasia
PURPOSE: To describe the previously unreported successful treatment of presumptive Pythium keratitis (PK) with medical therapy alone. METHODS: A 42-year-old female homemaker presented to us with a 15-day history of pain and redness in the right eye after a trivial injury. Her vision was 20/80 at presentation. Slit-lamp biomicroscopy revealed a central, dense and dry-looking, grayish-white infiltrate reaching mid stroma. The infiltrate had feathery margins and was surrounded by multiple tentacle-like lesions and peripherally expanding pinhead-sized subepithelial lesions...
February 15, 2017: Cornea
https://www.readbyqxmd.com/read/28203186/real-life-iluvien-fluocinolone-acetonide-case-study-rapid-drying-of-the-macula-and-improved-vision-within-2-years-after-therapy-initiation
#4
Hibba Quhill, Fahd Quhill
IMPORTANCE: A case showing sustained structural and functional responses 2 years after a single treatment with ILUVIEN (0.2 µg/day fluocinolone acetonide, FAc) despite suboptimal responses to ranibizumab. OBSERVATIONS: A 68-year-old female patient with diabetic macular oedema (DME) from type 2 diabetes mellitus was first diagnosed in October 2010 and had a baseline visual acuity (VA) of 46 Early Treatment Diabetic Retinopathy Study (ETDRS) letters in the left eye...
September 2016: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28203053/refractive-outcomes-and-safety-of-the-implantable-collamer-lens-in-young-low-to-moderate-myopes
#5
Paul J Dougherty, Taylor Priver
PURPOSE: To evaluate visual and refractive outcomes and safety of implantable collamer lens (ICL) implantation in low-to-moderate myopia. SETTING: Private Practice - Dougherty Laser Vision, Westlake Village, CA, USA. METHODS: A chart review was performed in 56 (104 eyes) consecutive patients who underwent implantation of the Visian ICL V4 model. Inclusion criteria were age between 21 and 40 years, spherical equivalent between -3.00 D and -10...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28198730/conjunctival-impression-cytology-and-dry-eye-in-patients-with-ulcerative-colitis-a-pilot-study
#6
Pembe Oltulu, Refik Oltulu, Mehmet Asil, Gunhal Satirtav, Enver Mirza
PURPOSE: The aim of this study was to compare signs of dry eye between ulcerative colitis (UC) patients and healthy subjects. METHODS: Fifteen patients with UC (group 1) and 15 healthy subjects (group 2) were enrolled in this study. Tear volume measurement, Schirmer-I test with no anesthetic, tear break-up time, and conjunctival impression cytology (CIC) were evaluated in both groups. RESULTS: Patients with UC showed lower tear volumes when compared with healthy subjects (P<0...
February 14, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28197326/efficacy-of-carboxymethylcellulose-and-hyaluronate-in-dry-eye-disease-a-systematic-review-and-meta-analysis
#7
Jae Kyeong Song, Kiheon Lee, Hwa Yeon Park, Joon Young Hyon, Seung-Won Oh, Woo Kyung Bae, Jong-Soo Han, Se Young Jung, Yoo Jin Um, Ga-Hye Lee, Ji Hye Yang
BACKGROUND: The efficacy of two artificial tears, carboxymethylcellulose (CMC) and hyaluronate (HA), was compared in the treatment of patients with dry eye disease. METHODS: We conducted a systematic review and meta-analysis on randomized controlled trials in the PubMed, Embase, Cochrane Library, and ClinicalTrials.gov databases. The efficacy was compared in terms of the mean change from baseline in tear break-up time. The meta-analysis was conducted using both random and fixed effect models...
January 2017: Korean Journal of Family Medicine
https://www.readbyqxmd.com/read/28196268/three-cases-of-exotropic-moebius-syndrome
#8
Abbas Bagheri, Mohaddese Feizi
Moebius syndrome is characterized by congenital facial palsy and limitation in horizontal gaze. The surgical results of the exotropic pattern are rare and have not been published before. The authors report three cases of exotropic Moebius syndrome. Maximal weakening of the lateral rectus muscles followed by strengthening of the medial recti in exotropic Moebius syndrome can improve exotropia significantly. Most of these cases also need some measures to relieve the often associated severe dry eye. [J Pediatr Ophthalmol Strabismus...
February 14, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28192377/application-of-casia-ss-1000-optical-coherence-tomography-tear-meniscus-imaging-in-testing-the-efficacy-of-new-strip-meniscometry-in-dry-eye-diagnosis
#9
Megumi Shinzawa, Murat Dogru, Keiichi Miyasaka, Jun Shimazaki, Tetsuju Sekiryu
PURPOSE: To investigate the applicability of CASIA SS-1000 anterior-segment optical coherence tomography (AS-OCT) imaging parameters in testing the efficacy of the new strip meniscometry (SM) namely "Strip Meniscometry Tube" (SMTube) in the diagnosis of dry eyes. METHODS: Forty-three eyes of 22 patients (4 men and 18 women) with definite dry eye disease (DED) and 49 eyes of 28 normal controls (6 men and 22 women) were studied. All subjects underwent symptom questionnaires, SMTube, the Schirmer-1 test, tear film break-up time measurement, vital staining examinations, as well as tear meniscus height (TMH) and TM area (TMA) measurements using an AS-OCT system...
January 6, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28187895/parallel-definition-of-tear-film-maps-on-distributed-memory-clusters-for-the-support-of-dry-eye-diagnosis
#10
Jorge González-Domínguez, Beatriz Remeseiro, María J Martín
BACKGROUND AND OBJECTIVES: The analysis of the interference patterns on the tear film lipid layer is a useful clinical test to diagnose dry eye syndrome. This task can be automated with a high degree of accuracy by means of the use of tear film maps. However, the time required by the existing applications to generate them prevents a wider acceptance of this method by medical experts. Multithreading has been previously successfully employed by the authors to accelerate the tear film map definition on multicore single-node machines...
February 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28184150/randomized-masked-in-vitro-comparison-of-three-commercially-available-tear-film-osmometers
#11
Guillermo Rocha, Eric Gulliver, Armand Borovik, Clara C Chan
PURPOSE: The purpose of this study was to compare the precision and accuracy of commercially available tear film osmometers. METHODS: Contrived tear solution target values representing the physiological range of tear osmolarity (normal eyes 297 mOsm/L, moderately dry eyes 342 mOsm/L, and severe dry eyes 383 mOsm/L) were constructed using a mix of mono- and divalent electrolytes, metabolites, serum albumin, and pH balanced to 7.4. Solution values were randomized and masked from the investigators during testing...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28183173/effect-of-alcohol-dehydrogenase-1c-adh1c-genotype-on-vitamin-a-restriction-and-marbling-in-korean-native-steers
#12
H G Lee, D Q Peng, U S Jung, J S Lee, W S Kim, Y H Jo, M J Kim, Y K Oh, Y C Baek, S G Hwang
Objective: This work was to find the correlation of ADH1C (Alcohol Dehydrogenase 1C) genotype with vitamin A reduction and carcass traits during the vitamin A restriction period. Methods: In study 1, 60 Korean native steers were fed a diet (890 IU/kg) with 8,000 IU and 0 IU of supplemental premix vitamin A/kg of DM (Dry matter) for control and treatment group, respectively. The levels of serum vitamin A were analyzed through HPLC, and the ADH1C genotype was analyzed based on PCR-RFLP (polymerase chain reaction-restriction fragment length polymorphism; 78...
January 26, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28182154/anterior-segment-findings-in-women-with-polycystic-ovary-syndrome
#13
Seda Karaca Adıyeke, Ibrahim Karaca, Suna Yıldırım, Mehmet Adıyeke, İbrahim Uyar, Gamze Türe
OBJECTIVES: This study aimed to investigate the anterior segment in women with polycystic ovary syndrome (PCOS) and to compare them with those of healthy reproductive-age female volunteers. MATERIALS AND METHODS: The study included 50 right eyes of 50 women with PCOS (group 1) and 50 right eyes of 50 healthy women (group 2). Intraocular pressure, Schirmer's test, tear film break-up time and central corneal thickness were evaluated in all subjects. Correlations between serum hormone (estradiol and testosterone) levels and observed findings were also investigated...
January 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28181961/the-association-of-dry-eye-symptom-severity-and-comorbid-insomnia-in-us-veterans
#14
Anat Galor, Benjamin E Seiden, Jasmine J Park, William J Feuer, Allison L McClellan, Elizabeth R Felix, Roy C Levitt, Constantine D Sarantopoulos, Douglas M Wallace
PURPOSE: To investigate the association between dry eye (DE) and insomnia symptom severity. METHODS: Cross-sectional study of 187 individuals seen in the Miami Veterans Affairs eye clinic. An evaluation was performed consisting of questionnaires regarding insomnia (insomnia severity index [ISI]) and DE symptoms, including ocular pain, followed by a comprehensive ocular surface examination. Using a two-step cluster analysis based on intensity ratings of ocular pain, the patient population was divided into two groups (high and low ocular pain groups: HOP and LOP)...
January 6, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28181960/barriers-to-glaucoma-medication-compliance-among-veterans-dry-eye-symptoms-and-anxiety-disorders
#15
Jack Stringham, Noy Ashkenazy, Anat Galor, Sarah R Wellik
OBJECTIVE: To identify barriers to compliance of medical treatment for glaucoma among veterans. METHODS: Patients with glaucoma from the Miami Veterans Affairs Eye Clinic (n=74) filled out a 63-question survey regarding dry eye symptoms, concurrent systemic disease, and medications. The association between glaucoma medical compliance was defined as self-reported adherence to drop regimens greater than 75% of the time. RESULTS: Eighty percent of veterans (n=59) reported compliance with glaucoma therapy...
January 6, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28181147/a-clinic-based-survey-of-clinical-characteristics-and-practice-pattern-of-dry-eye-in-japan
#16
Motoko Kawashima, Masakazu Yamada, Kazuhisa Suwaki, Chika Shigeyasu, Miki Uchino, Yoshimune Hiratsuka, Norihiko Yokoi, Kazuo Tsubota
INTRODUCTION: The aim of this study was to investigate the clinical characteristics and practice pattern of patients with dry eye disease (DED) in eye clinics across Japan. METHODS: A multi-center, cross-sectional study was conducted among patients with DED who visited eye clinics in Japan. Subjective symptoms, patient's background, ocular surface features, and tear function were evaluated. Main outcome measures were tear break-up time (TBUT), Schirmer I value, kerato-conjunctival staining score, and dry eye symptom questionnaire score...
February 8, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28179131/rasch-analysis-of-three-dry-eye-questionnaires-and-correlates-with-objective-clinical-tests
#17
Colm McAlinden, Rongrong Gao, Qinmei Wang, Senmiao Zhu, Jing Yang, Ayong Yu, Anthony J Bron, Jinhai Huang
PURPOSE: To assess the psychometric properties of Chinese versions of the Ocular Comfort Index (OCI), Ocular Surface Disease Index (OSDI) and McMonnies questionnaires. Further, to assess the correlation between questionnaire scores and objective dry eye disease (DED) clinical tests. METHODS: Translated versions of the OCI, OSDI and McMonnies questionnaires were completed in a random order by 238 participants with DED. Objective clinical tests included visual acuity (VA), fluorescein tear film break-up time (TBUT), corneal fluorescein staining, Schirmer I testing and meibomian gland grading...
February 4, 2017: Ocular Surface
https://www.readbyqxmd.com/read/28178141/a-non-surgical-approach-to-the-management-of-exposure-keratitis-due-to-facial-palsy-by-using-mini-scleral-lenses
#18
Victor Zaki
RATIONALE: This is a retrospective study aimed to determine the efficacy of mini-scleral contact lens in protecting the cornea and improving vision in cases of facial palsy. PATIENT CONCERNS: Patients with facial palsy get exposure keratitis because the cornea is dry. They feel pain, discomfort and excessive watering. If left untreated, it leads to permanent damage to the cornea and loss of good functional vision. Mini-scleral lens keep the cornea covered by saline solution all wearing hours...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28177355/impacts-of-a-leptin-snp-on-growth-performance-and-carcass-characters-in-finishing-steers-studied-over-time
#19
P J Kononoff, P J Defoor, M J Engler, R S Swingle, J F Gleghorn, S T James, F L S Marquess
A total of 2,948 steers (mean initial BW = 568.9 ± 49.4 kg) were used to evaluate the effect of the LEP R25C SNP genotype on feed intake, growth performance, and carcass characteristics over time. Steers were grouped into 5 blocks, each consisting of 10 pens initially, and then at approximately 24 d prior to the assigned slaughter date, cattle in each pen were randomly selected either to remain in the pen they were in (group A) or to be assigned to a new pen (group B). Steers were allocated to 5 blocks and 6 harvest weeks (-3, -2, 0, 2, 3, and 4 wk) relative to the projected end point...
January 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28176024/hyperosmotic-stress-induces-atp-release-and-changes-in-p2x7-receptor-levels-in-human-corneal-and-conjunctival-epithelial-cells
#20
Ana Guzman-Aranguez, María J Pérez de Lara, Jesús Pintor
Tear hyperosmolarity is a key event in dry eye. In this work, we analyzed whether hyperosmolar challenge induces ATP release on the ocular surface. Moreover, as extracellular ATP can activate P2X7 receptor, the changes in P2X7 protein levels and its involvement in pathological process triggered by hypertonic treatment were also examined. High-performance liquid chromatography analysis revealed that ATP levels significantly increased in human corneal and conjunctival epithelial cells exposed to hyperosmotic challenge as well as in dry eye patients as compared to control subjects...
February 7, 2017: Purinergic Signalling
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