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https://www.readbyqxmd.com/read/28810000/effect-of-a-blueberry-derived-antioxidant-matrix-on-infrared-a-induced-gene-expression-in-human-dermal-fibroblasts
#1
Susanne Grether-Beck, Jean Krutmann, Katherine Wilkens, Kasey D'Amato
<p>There is compelling evidence that Infrared A (IRA) from natural sunlight contributes to photoaging of human skin by inducing the expression of matrix metalloproteinase-1 (MMP-1) expression in human dermal fibroblasts. Corresponding mechanistic studies have shown that IRA does so by increasing the production of reactive oxygen species in irradiated cells. In the present study, we therefore asked if treatment of primary human skin fibroblasts with a blueberry-derived antioxidant matrix (BerrimatrixTM), which is employed as an active ingredient in commercially available skin care products that are topically applied, can prevent IRA-induced MMP-1 expression in these cells...
August 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28807875/bioactive-isoflavones-from-pueraria-lobata-root-and-starch-different-extraction-techniques-and-carbonic-anhydrase-inhibition
#2
Andrei Mocan, Simone Carradori, Marcello Locatelli, Daniela Secci, Stefania Cesa, Adriano Mollica, Simona Riga, Andrea Angeli, Claudiu T Supuran, Christian Celia, Luisa Di Marzio
Kudzu, the dried root of an important edible plant (Pueraria lobata), is used in Traditional Chinese Medicine for the important nutritional value strictly related to its isoflavone derivatives. These compounds characterize the quality of kudzu contained in different preparations, as pharmaceutical ingredient as well as dietary/food supplement (e.g. starch). The optimization of the isoflavones recovery, monitored by HPLC-PDA, through different innovative and conventional extraction techniques, e.g. microwave-assisted, ultrasound-assisted and conventional extraction, represented a suitable challenge in food industry and natural products evaluation...
August 11, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28805193/optics-of-plasmon-exciton-nanomaterials
#3
Maxim Sukharev, Abraham Nitzan
This review provides a brief introduction to the physics of coupled exciton-plasmon systems, the theoretical description and experimental manifestation of such phenomena, followed by an account of the state-of-the-art methodology for the numerical simulations of such phenomena and supplemented by a number of FORTRAN codes, by which the interested reader can introduce himself/herself to the practice of such simulations. Applications to CW light scattering as well as transient response and relaxation are described...
August 14, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28802794/a-novel-and-organic-solvent-free-preparation-of-solid-lipid-nanoparticles-using-natural-biopolymers-as-natural-emulsifier-and-stabilizer
#4
Jingyi Xue, Taoran Wang, Qiaobin Hu, Mingyong Zhou, Yangchao Luo
In this work, a new and novel organic solvent-free and synthetic surfactant-free method was reported to fabricate stable solid lipid nanoparticles (SLNs) from stearic acid, sodium caseinate (NaCas) and pectin, as well as water. Melted stearic acid was directly emulsified into an aqueous phase containing NaCas and pectin, followed by pH adjustment and thermal treatment to induce the formation of a compact and dense polymeric coating which stabilized SLNs. The preparation procedures and formulations were comprehensively optimized...
August 9, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28800540/rapid-extraction-of-amomum-tsao-ko-essential-oil-and-determination-of-its-chemical-composition-antioxidant-and-antimicrobial-activities
#5
Qi Cui, Li-Tao Wang, Ju-Zhao Liu, Hui-Mei Wang, Na Guo, Cheng-Bo Gu, Yu-Jie Fu
A simple, green and efficient extraction method named modified-solvent free microwave extraction (M-SFME) was employed for the extraction of essential oils (EOs) from Amomun tsao-ko. The process of M-SFME was optimized with the prominent preponderance of such higher extraction yield (1.13%) than those of solvent free microwave extraction (SFME, 0.91%) and hydrodistillation (HD, 0.84%) under the optimal parameters. Thirty-four volatile substances representing 95.4% were identified. The IC50 values of EOs determined by DPPH radical scavenging activity and β-carotene/linoleic acid bleaching assay were 5...
August 3, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28799777/functional-and-therapeutic-potential-of-inulin-a-comprehensive-review
#6
Waqas Ahmed, Summer Rashid
Inulin as a heterogeneous blend of fructose polymers is diversely found in nature primarily as storage carbohydrates in plants. Besides, inulin is believed to induce certain techno-functional and associated properties in food systems. Inulin owing to its foam forming ability has been successfully used as fat replacer in quite a wide range of products as dairy and baked products. Furthermore, it is known to impart certain nutritional and therapeutic benefits that extend apart to improve health and reduce the risk of many lifestyle related diseases...
August 11, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28796916/fragrance-contact-allergens-in-5-588-cosmetic-products-identified-through-a-novel-smartphone-application
#7
Niels Højsager Bennike, Nikoline Bang Oturai, Stine Müller, Christel Søgaard Kirkeby, Claus Jørgensen, Anne Beck Christensen, Claus Zachariae, Jeanne Duus Johansen
BACKGROUND: More than 25% of the adult European population suffers from contact allergy, with fragrance substances recognized as one of the main causes. Since 2005, 26 fragrance contact allergens have been mandatory to label in cosmetic products within the EU if present at 10 ppm or above in leave-on and 100 ppm or above in wash-off cosmetics. OBJECTIVE: To examine exposure, based on ingredient labelling, to the 26 fragrances in a sample of 5,588 fragranced cosmetic products...
August 10, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28792963/unzipping-zipf-s-law
#8
Sander Lestrade
In spite of decades of theorizing, the origins of Zipf's law remain elusive. I propose that a Zipfian distribution straightforwardly follows from the interaction of syntax (word classes differing in class size) and semantics (words having to be sufficiently specific to be distinctive and sufficiently general to be reusable). These factors are independently motivated and well-established ingredients of a natural-language system. Using a computational model, it is shown that neither of these ingredients suffices to produce a Zipfian distribution on its own and that the results deviate from the Zipfian ideal only in the same way as natural language itself does...
2017: PloS One
https://www.readbyqxmd.com/read/28782394/essential-oil-obtained-from-micropropagated-lavender-its-effect-on-hsf-cells-and-application-in-cosmetic-emulsion-as-a-natural-protective-substance
#9
D Andrys, M Adaszyńska-Skwirzyńska, D Kulpa
The aim of the study was to determine the influence of the essential oils isolated from the field - grown and micropropagated in vitro narrow - leaved lavender of the 'Munstead' cultivar, on human skin cells, and their capability to synthesise procollagen. The amount of procollagen type I produced by fibroblast cells was determined using ELISA kit. Essential oil isolated from micropropagated lavender was further used as a protective ingredient against the development of microorganisms in O/W cosmetic emulsion...
August 7, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28777137/natural-compounds-for-skin-tissue-engineering-by-electrospinning-of-nylon-beta-vulgaris
#10
Parviz Ranjbarvan, Matin Mahmoudifard, Mousa Kehtari, Ali Babaie, Shokoh Hamedi, Samaneh Mirzaei, Masoud Soleimani, Simzar Hosseinzadeh
Natural compounds containing polysaccharide ingredients have been employed as candidates for treatment of skin tissue. Herein, for the first time, electrospinning setup was proposed to fabricate an efficient composite nanofibrous structure of Beta vulgaris (obtained from Beet [Chenopodiaceae or Amaranthaceae]) belonged to polysaccharides and an elastic polymer named nylon 66 for skin tissue engineering. Both prepared scaffolds including noncomposite and composite types were studied by Scanning electron microscope (SEM), FTIR spectroscopy, mechanical assay, and contact angle...
August 2, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28776612/overcoming-t-gondii-infection-and-intracellular-protein-nanocapsules-as-biomaterials-for-ultrasonically-controlled-drug-release
#11
REVIEW
M S Aw, L Paniwnyk
One of the pivotal matters of concern in intracellular drug delivery is the preparation of biomaterials containing drugs that are compatible with the host target. Nanocapsules for oral delivery are found to be suitable candidates for targeting Toxoplasma gondii (T. gondii), a maneuvering and smart protozoic parasite found across Europe and America that causes a subtle but deadly infection. To overcome this disease, there is much potential of integrating protein-based cells into bioinspired nanocompartments such as via biodegradable cross-linked disulfide polyelectrolyte nanoparticles...
August 4, 2017: Biomaterials Science
https://www.readbyqxmd.com/read/28765523/robust-spin-correlations-at-high-magnetic-fields-in-the-harmonic-honeycomb-iridates
#12
K A Modic, B J Ramshaw, J B Betts, Nicholas P Breznay, James G Analytis, Ross D McDonald, Arkady Shekhter
The complex antiferromagnetic orders observed in the honeycomb iridates are a double-edged sword in the search for a quantum spin-liquid: both attesting that the magnetic interactions provide many of the necessary ingredients, while simultaneously impeding access. Focus has naturally been drawn to the unusual magnetic orders that hint at the underlying spin correlations. However, the study of any particular broken symmetry state generally provides little clue about the possibility of other nearby ground states...
August 1, 2017: Nature Communications
https://www.readbyqxmd.com/read/28764166/phytotherapy-in-streptococcusagalactiae-an-overview-of-the-medicinal-plants-effective-against-streptococcus-agalactiae
#13
REVIEW
Somayeh Delfani, Mahmoud Bahmani, Reza Mohammadrezaei-Khorramabadi, Mahmoud Rafieian-Kopaei
Streptococcus agalactiae is a spherical and Gram-positive bacterium that causes postpartum sepsis, endometritis, chorioamnionitis and premature delivery in pregnant women. The use of herbs and natural ingredients for the treatment of various disorders has been common. The present review is a report on the medicinal plants with anti-Streptococcus agalactiae effects. In this review, the search was carried out in Web of Science, PubMed, Scopus, Google Scholar and Science direct by keywords such as bacteria, Streptococcus agalactiae and medicinal plants...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28763983/biogenic-antioxidative-and-anti-inflammatory-aryl-polyketides-from-the-venerid-bivalve-clam-paphia-malabarica
#14
Minju Joy, Kajal Chakraborty
Chemical investigation of ethyl acetate-methanol extract of the venerid bivalve clam Paphia malabarica led to isolation of three unprecedented aryl polyketide derivatives, characterized as (E)-12-(17-ethyl-tetrahydro-16-hydroxy-15-(methyl pentanoate)-14-oxo-2H-pyran-13-yl)-9-methyl-but-11-enyl benzoate (1), isobutyl-13-(6-(benzoyloxy)-10-methylpentyl)-tetrahydro-13-methyl-2H-pyran-17-carboxylate (2) and (13-(methoxycarbonyl)-11-((E)-18-ethylhexa-16,19-dienyl)-12-propyl-cyclohex-10-enyl)-methyl-3-hydroxy benzoate (3)...
December 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28762740/in-situ-characterization-of-pharmaceutical-formulations-by-dynamic-nuclear-polarization-enhanced-mas-nmr
#15
Qing Zhe Ni, Fengyuan Yang, Thach V Can, Ivan V Sergeyev, Suzanne M D'Addio, Sudheer K Jawla, Yongjun Li, Maya P Lipert, Wei Xu, Robert Thomas Williamson, Anthony Leone, Robert G Griffin, Yongchao Su
A principle advantage of magic angle spinning (MAS) NMR spectroscopy lies in its ability to determine molecular structure in a non-invasive and quantitative manner. Accordingly, MAS should be widely applicable to studies of the structure of active pharmaceutical ingredients (API) and formulations. However, the low sensitivity encountered in spectroscopy of natural abundance API's present at low concentration has limited the success of MAS experiments. Dynamic nuclear polarization (DNP) enhances NMR sensitivity and can be used to circumvent this problem provided that suitable paramagnetic polarizing can be incorporated into the system without altering the integrity of solid dosages...
August 1, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28762217/acute-toxicity-and-sublethal-effects-of-terpenoids-and-essential-oils-on-the-predator-chrysoperla-externa-neuroptera-chrysopidae
#16
R V Castilhos, A D Grützmacher, J R Coats
The search for new safer insecticides has increased in recent agriculture. Botanical compounds such as terpenoids and plant essential oils with insecticidal activity could represent important tools in pest management, and their risk assessment against non-target organisms is necessary since they may serve as a precursor for the synthesis of new insecticide active ingredients. For this study, the acute toxicity and sublethal effects of seven terpenoids and three essential oils with recognized insecticidal activity were evaluated on the predator Chrysoperla externa (Hagen) (Neuroptera: Chrysopidae) in laboratory bioassays...
July 31, 2017: Neotropical Entomology
https://www.readbyqxmd.com/read/28761827/spectroscopic-and-spectrometric-methods-used-for-the-screening-of-certain-herbal-food-supplements-suspected-of-adulteration
#17
Cristina Mateescu, Anca Mihaela Popescu, Gabriel Lucian Radu, Tatiana Onisei, Adina Elena Raducanu
Purpose: This study was carried out in order to find a reliable method for the fast detection of adulterated herbal food supplements with sexual enhancement claims. As some herbal products are advertised as "all natural", their "efficiency" is often increased by addition of active pharmaceutical ingredients such as PDE-5 inhibitors, which can be a real health threat for the consumer. Methodes: Adulterants, potentially present in 50 herbal food supplements with sexual improvement claims, were detected using 2 spectroscopic methods - Raman and Fourier Transform Infrared - known for reliability, reproductibility, and an easy sample preparation...
June 2017: Advanced Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28758221/biological-medicinal-and-toxicological-significance-of-eucalyptus-leaf-essential-oil-a-review
#18
REVIEW
Ashok K Dhakad, Vijay V Pandey, Sobia Beg, Janhvi M Rawat
The genus Eucalyptus L'Heritier comprises about 900 species, of which more than 300 species contain volatile essential oil in their leaves. About 20 species, within these, have a high content of 1,8-cineole (more than 70 %), commercially used for the production of essential oils in pharmaceutical and cosmetic industries. However, Eucalyptus is extensively planted for pulp, plywood, solid wood production but its leaf aromatic oil has astounding widespread biological activities including antimicrobial, antiseptic, antioxidant, chemotherapy agent, respiratory and gastrointestinal disorders treatment, wound healing, and insecticidal/insect repellent, herbicidal, acaricidal, nematicidal, and perfumes, soap making and grease remover...
July 31, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28757496/pharmacy-testing-and-the-language-of-truth-in-renaissance-italy
#19
Valentina Pugliano
This article examines the role of testing and innovation in sixteenthcentury Italian pharmacy. I argue that apothecaries were less concerned with testing drugs for efficacy or creating novel products than with reactivating an older Mediterranean pharmacological tradition and studying the materials on which it relied. Their practice was not driven by radical experimentation but by a "culture of tweaking"-of minute operational changes to existing recipes and accommodation of their textual variants-which was rooted in the guild economy fostering incremental over radical innovation and in a humanist reevaluation of past autorities...
2017: Bulletin of the History of Medicine
https://www.readbyqxmd.com/read/28756642/factors-influencing-the-quality-of-myrmecia-pilosula-jack-jumper-ant-venom-for-use-in-in-vitro-and-in-vivo-diagnosis-of-allergen-sensitization-and-in-allergen-immunotherapy
#20
T Wanandy, H E Dwyer, L McLean, N W Davies, D Nichols, N Gueven, S G A Brown, M D Wiese
BACKGROUND: Allergen immunotherapy uses pharmaceutical preparations derived from naturally occurring source materials, which contain water-soluble allergenic components responsible for allergic reactions. The success of in vivo and in vitro diagnosis in allergen sensitization and allergen immunotherapy largely depends on the quality, composition and uniformity of allergenic materials used to produce the active ingredients, and the formulation employed to prepare finished products. OBJECTIVES: We aimed to examine the factors influencing batch-to-batch consistency of Jack Jumper (Myrmecia pilosula) ant venom (JJAV) in the form of Active Pharmaceutical Ingredient (AI) and informed whether factors such as temperature, artificial light and container materials influence the quality of JJAV AIs...
July 30, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
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