keyword
MENU ▼
Read by QxMD icon Read
search

Nana

keyword
https://www.readbyqxmd.com/read/28938053/persistent-hotspots-of-lymphatic-filariasis-microfilaraemia-despite-14-years-of-mass-drug-administration-in-ghana
#1
Nana-Kwadwo Biritwum, Paul Yikpotey, Benjamin K Marfo, Samuel Odoom, Ernest O Mensah, Odame Asiedu, Bright Alomatu, Edward T Hervie, Abednego Yeboah, Serge Ade, Sven G Hinderaker, Anthony Reid, Kudakwashe C Takarinda, Benjamin Koudou, Joseph B Koroma
Background: Among the 216 districts in Ghana, 98 were declared endemic for lymphatic filariasis in 1999 after mapping. Pursuing the goal of elimination, WHO recommends annual treatment using mass drugs administration (MDA) for at least 5 years. MDA was started in the country in 2001 and reached national coverage in 2006. By 2014, 69 districts had 'stopped-MDA' (after passing the transmission assessment survey) while 29 others remained with persistent microfilaraemia (mf) prevalence (≥1%) despite more than 11 years of MDA and were classified as 'hotspots'...
December 1, 2016: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28935965/aromatic-side-chain-conformational-switch-on-the-surface-of-the-rna-recognition-motif-enables-rna-discrimination
#2
Nana Diarra Dit Konté, Miroslav Krepl, Fred F Damberger, Nina Ripin, Olivier Duss, Jiří Šponer, Frédéric H-T Allain
The cyclooxygenase-2 is a pro-inflammatory and cancer marker, whose mRNA stability and translation is regulated by the CUG-binding protein 2 interacting with AU-rich sequences in the 3' untranslated region. Here, we present the solution NMR structure of CUG-binding protein 2 RRM3 in complex with 5'-UUUAA-3' originating from the COX-2 3'-UTR. We show that RRM3 uses the same binding surface and protein moieties to interact with AU- and UG-rich RNA motifs, binding with low and high affinity, respectively. Using NMR spectroscopy, isothermal titration calorimetry and molecular dynamics simulations, we demonstrate that distinct sub-states characterized by different aromatic side-chain conformations at the RNA-binding surface allow for high- or low-affinity binding with functional implications...
September 21, 2017: Nature Communications
https://www.readbyqxmd.com/read/28935541/a-novel-controlled-drug-delivery-system-based-on-alginate-hydrogel-chitosan-micelle-composites
#3
Zhaotong Cong, Yanbin Shi, Yang Wang, Yanhong Wang, Jing'e Niu, Nana Chen, Haoyue Xue
In this study, we present a novel cross-linked unimolecular micelle based on chitosan. For controlling drug delivery via oral administration, emodin (EMO) encapsulated micelles were loaded into sodium alginate hydrogel matrix to construct the pH-sensitive hydrogel/micelle composites. The optimized formulation of micelle that consists of 8.06% CaCl2, 1.71% chitosan and 26.52% β-GP was obtained by the combination of Box-Behnken experimental design and response surface methodology. The morphological analysis showed that the micelles exhibited a smaller diameter of about 80nm in aqueous solution, but dilated to 100-200nm in hydrogel owing to the formation of polyelectrolyte complexes...
September 18, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28934218/prevalence-of-intestinal-parasites-among-inmates-in-midwest-brazil
#4
Larissa Gabrielle Curval, Adriana de Oliveira França, Henrique Jorge Fernandes, Rinaldo Pôncio Mendes, Lídia Raquel de Carvalho, Minoru German Higa, Eduardo de Castro Ferreira, Maria Elizabeth Cavalheiros Dorval
BACKGROUND: Intestinal parasitic infections constitute a public health issue in developing countries, with prevalence rates as high as 90%, a figure set to escalate as the socioeconomic status of affected populations deteriorates. Investigating the occurrence of these infections among inmates is critical, since this group is more vulnerable to the spread of a number of infectious illnesses. METHODS: This cross-sectional, analytical, quantitative study was conducted in July 2015 at prison facilities located in Midwest Brazil to estimate the prevalence of parasitic infection among inmates...
2017: PloS One
https://www.readbyqxmd.com/read/28932656/oxygen-rich-lithium-oxide-phases-formed-at-high-pressure-for-potential-lithium-air-battery-electrode
#5
Wenge Yang, Duck Young Kim, Liuxiang Yang, Nana Li, Lingyun Tang, Khalil Amine, Ho-Kwang Mao
The lithium-air battery has great potential of achieving specific energy density comparable to that of gasoline. Several lithium oxide phases involved in the charge-discharge process greatly affect the overall performance of lithium-air batteries. One of the key issues is linked to the environmental oxygen-rich conditions during battery cycling. Here, the theoretical prediction and experimental confirmation of new stable oxygen-rich lithium oxides under high pressure conditions are reported. Three new high pressure oxide phases that form at high temperature and pressure are identified: Li2O3, LiO2, and LiO4...
September 2017: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://www.readbyqxmd.com/read/28927955/modified-hybrid-fixation-using-absorbable-plate-and-screw-for-mandibular-advancement-surgery
#6
Koichiro Ueki, Kunio Yoshizawa, Akinori Moroi, Asami Hotta, Takamitsu Tsutsui, Kenichi Fukaya, Ryota Hiraide, Akihiro Takayama, Tatsuya Tsunoda, Yuki Saito, Nana Baba, Momoko Sato
PURPOSE: The purpose of this study was to examine the skeletal stability of mandibular advancement after sagittal split ramus osteotomy (SSRO) with modified hybrid fixation using absorbable plates and screws. MATERIALS AND METHODS: A total of 54 Japanese patients were enrolled in this study. Of them, 23 who were diagnosed with mandibular prognathism underwent setback surgery with bi-cortical plate fixation using absorbable plates and screws (setback group). Another 23 who were diagnosed with mandibular retrognathism underwent advancement surgery with modified hybrid fixation using absorbable plates (advance group), and 8 who were diagnosed with mandibular retrognathism underwent advancement surgery with titanium plates (titanium group)...
August 10, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28925690/fiber-alignment-and-liquid-crystal-orientation-of-cellulose-nanocrystals-in-the-electrospun-nanofibrous-mats
#7
Weiguang Song, Dagang Liu, Nana Prempeh, Renjie Song
Sulfate cellulose nanocrystal (CNC) dispersions always present specific self-assembled cholesteric mesophases which is easily affected by the inherent properties of particle size, surface charge and repulsion or affinity interaction, and external field force generated from ionic potential of added electrolytes, magnetic, electric, and/or mechanical shearing or stretching. Aiming at understanding the liquid crystal orientation and fiber alignment under high-voltage electric field, randomly distributed, uniform-aligned, or core-sheath nanofibrous mats involving PVA and charged CNCs were electrospun; and amongst them, specific straight arrayed fine nanofibers wi...
September 19, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28924741/spectrum-of-infectious-diseases-among-newly-arrived-eritrean-refugees-in-switzerland-a-cross-sectional-study
#8
Afona Chernet, Andreas Neumayr, Christoph Hatz, Kerstin Kling, Véronique Sydow, Katharina Rentsch, Jürg Utzinger, Nicole Probst-Hensch, Hanspeter Marti, Beatrice Nickel, Niklaus D Labhardt
OBJECTIVES: Our study aimed at determining the prevalence of selected infectious diseases among recently arrived Eritrean refugees in Switzerland. METHODS: In this cross-sectional study, asymptomatic Eritrean migrants aged ≥16 years who arrived <24 months ago were recruited at refugee centres in Switzerland. Infectious disease screening included serology for HIV, hepatitis B and C, syphilis and schistosomiasis, polymerase chain reaction (PCR) for malaria, stool microscopy for helminths and intestinal protozoa and circulating cathodic antigen (CCA) testing in urine for schistosomiasis...
September 19, 2017: International Journal of Public Health
https://www.readbyqxmd.com/read/28923401/pharmacological-blockade-of-cholesterol-trafficking-by-cepharanthine-in-endothelial-cells-suppresses-angiogenesis-and-tumor-growth
#9
Junfang Lyu, Eun Ju Yang, Sarah A Head, Nana Ai, Baoyuan Zhang, Changjie Wu, Ruo-Jing Li, Yifan Liu, Chen Yang, Yongjun Dang, Ho Jeong Kwon, Wei Ge, Jun O Liu, Joong Sup Shim
Cholesterol is an important modulator of membrane protein function and signaling in endothelial cells, thus making it an emerging target for anti-angiogenic agents. In this study, we employed a phenotypic screen that detects intracellular cholesterol distribution in endothelial cells (HUVEC) and identified 13 existing drugs as cholesterol trafficking inhibitors. Cepharanthine, an approved drug for anti-inflammatory and cancer management use, was amongst the candidates, which was selected for in-depth mechanistic studies to link cholesterol trafficking and angiogenesis...
September 18, 2017: Cancer Letters
https://www.readbyqxmd.com/read/28923097/impact-of-perioperative-nutritional-status-on-the-outcome-of-abdominal-surgery-in-a-sub-saharan-africa-setting
#10
Christian Gael Mambou Tebou, Mazou N Temgoua, Agnès Esiene, Blondel Oumarou Nana, Jean Jacques Noubiap, Eugène Sobngwi
BACKGROUND: Malnutrition is a clinical condition of multifactorial etiologies and it is associated with several adverse outcomes. In high-income countries, malnutrition has been described as a determinant of delayed wound healing, surgical site infections and mortality in the postoperative period. There is limited information available regarding the outcome of surgery in malnourished patients in sub-Saharan Africa. METHODS: A cross-sectional analytic study was carried out between March and August 2014 in the visceral surgery and the emergency departments of the Yaounde Central Hospital in Cameroon...
September 18, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28923042/the-potential-of-a-self-assessment-tool-to-identify-healthcare-professionals-strengths-and-areas-in-need-of-professional-development-to-aid-effective-facilitation-of-group-based-person-centered-diabetes-education
#11
Vibeke Stenov, Gitte Wind, Timothy Skinner, Susanne Reventlow, Nana Folmann Hempler
BACKGROUND: Healthcare professionals' person-centered communication skills are pivotal for successful group-based diabetes education. However, healthcare professionals are often insufficiently equipped to facilitate person-centeredness and many have never received post-graduate training. Currently, assessing professionals' skills in conducting group-based, person-centered diabetes education primarily focus on experts measuring and coding skills on various scales. However, learner-centered approaches such as adequate self-reflective tools have been shown to emphasize professional autonomy and promote engagement...
September 18, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28922228/anesthesia-capacity-in-ghana-a-teaching-hospital-s-resources-and-the-national-workforce-and-education
#12
Mark A Brouillette, Alfred J Aidoo, Maria A Hondras, Nana A Boateng, Akwasi Antwi-Kusi, William Addison, Alec R Hermanson
BACKGROUND: Quality anesthetic care is lacking in low- and middle-income countries (LMICs). Global health leaders call for perioperative capacity reports in limited-resource settings to guide improved health care initiatives. We describe a teaching hospital's resources and the national workforce and education in this LMIC capacity report. METHODS: A prospective observational study was conducted at Komfo Anokye Teaching Hospital (KATH) in Kumasi, Ghana, during 4 weeks in August 2016...
September 14, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28920444/mri-findings-and-demographics-of-elastofibroma-dorsi-assessment-of-diffusion-weighted-imaging-and-contrast-enhancement-patterns
#13
Maho Tsubakimoto, Tsuneo Yamashiro, Nanae Tsuchiya, Masahiro Okada, Hiroki Maehara, Kaoru Kitsukawa, Sadayuki Murayama
Background Elastofibroma dorsi is a rare pseudotumoral lesion. Thus, there is no report of magnetic resonance imaging (MRI) findings that investigates multiple patients particularly with respect to diffusion-weighted imaging (DWI) findings and contrast enhancement patterns. Purpose To describe the imaging findings of elastofibroma on MRI, particularly DWI findings and contrast enhancement patterns, and to further investigate patient demographics. Material and Methods Forty-four patients with elastofibroma that underwent MRI were enrolled in this retrospective study...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28916900/were-all-carbapenemases-created-equal-treatment-of-ndm-producing-extensively-drug-resistant-enterobacteriaceae-a-case-report-and-literature-review
#14
REVIEW
Vindana Chibabhai, Trusha Nana, Norma Bosman, Teena Thomas, Warren Lowman
PURPOSE: There is currently a paucity of published literature focused on the treatment of infections caused by NDM-producing organisms. METHODS: We describe a case of a bacteraemia caused by an extensively drug-resistant (XDR) New Delhi metallo-β-lactamase (NDM)-producing Serratia marcescens and review the treatment options for XDR NDM-producing Enterobacteriaceae. RESULTS: Infections caused by New Delhi beta-lactamase (NDM)-producing Enterobacteriaceae are becoming increasingly prevalent worldwide...
September 15, 2017: Infection
https://www.readbyqxmd.com/read/28915250/multi-layered-mutation-in-hedgehog-related-genes-in-gorlin-syndrome-may-affect-the-phenotype
#15
Shoko Onodera, Akiko Saito, Daigo Hasegawa, Nana Morita, Katsuhito Watanabe, Takeshi Nomura, Takahiko Shibahara, Shinsuke Ohba, Akira Yamaguchi, Toshifumi Azuma
Gorlin syndrome is a genetic disorder of autosomal dominant inheritance that predisposes the affected individual to a variety of disorders that are attributed largely to heterozygous germline patched1 (PTCH1) mutations. PTCH1 is a hedgehog (Hh) receptor as well as a repressor, mutation of which leads to constitutive activation of Hh pathway. Hh pathway encompasses a wide variety of cellular signaling cascades, which involve several molecules; however, no associated genotype-phenotype correlations have been reported...
2017: PloS One
https://www.readbyqxmd.com/read/28910625/role-of-soil-to-leaf-tritium-transfer-in-controlling-leaf-tritium-dynamics-comparison-of-experimental-garden-and-tritium-transfer-model-results
#16
Masakazu Ota, Nana-Owusua A Kwamena, Steve Mihok, Volodymyr Korolevych
Environmental transfer models assume that organically-bound tritium (OBT) is formed directly from tissue-free water tritium (TFWT) in environmental compartments. Nevertheless, studies in the literature have shown that measured OBT/HTO ratios in environmental samples are variable and generally higher than expected. The importance of soil-to-leaf HTO transfer pathway in controlling the leaf tritium dynamics is not well understood. A model inter-comparison of two tritium transfer models (CTEM-CLASS-TT and SOLVEG-II) was carried out with measured environmental samples from an experimental garden plot set up next to a tritium-processing facility...
September 11, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28906542/illuminating-the-pathway-for-the-next-generation-of-cardiovascular-medicine-practitioners-and-researchers-highlights-of-the-joint-pascar-scc-clinical-symposium-on-hypertension-and-heart-failure-cameroon
#17
Martin H Abanda, Anastase Dzudie, Ba Hamadou, Yves Monkam, Henry Luma, Marie Solange Douala, Loryane Nganhyim, Bonaventure S Dzekem, Theophile N Nana, George Nel, Ana O Mocumbi, Simon Stewart, Karen Sliwa, Eugene Belley Priso
The Pan-African Society of Cardiology roadmap aims to achieve a 25% control of hypertension by the year 2025. Whether this is attainable or not depends largely on the capacity of healthcare providers and policy makers to address the rising prevalence of hypertension and its complications, including heart failure. Task sharing is fundamental in optimising hypertension control. The Clinical Research Education, Networking and Consultancy (CRENC) engaged with the Pan-African Society of Cardiology (PASCAR) and the Cameroon Cardiac Society (SCC) in a joint hypertension and heart failure symposium at the Douala General Hospital in 2016...
July 2017: Cardiovascular Journal of Africa
https://www.readbyqxmd.com/read/28905136/highly-sensitive-detection-of-esr1-mutations-in-cell-free-dna-from-patients-with-metastatic-breast-cancer-using-molecular-barcode-sequencing
#18
Nanae Masunaga, Naofumi Kagara, Daisuke Motooka, Shota Nakamura, Tomohiro Miyake, Tomonori Tanei, Yasuto Naoi, Masafumi Shimoda, Kenzo Shimazu, Seung Jin Kim, Shinzaburo Noguchi
PURPOSE: We aimed to develop a highly sensitive method to detect ESR1 mutations in cell-free DNA (cfDNA) using next-generation sequencing with molecular barcode (MB-NGS) targeting the hotspot segment (c.1600-1713). METHODS: The sensitivity of MB-NGS was tested using serially diluted ESR1 mutant DNA and then cfDNA samples from 34 patients with metastatic breast cancer were analyzed with MB-NGS. The results of MB-NGS were validated in comparison with conventional NGS and droplet digital PCR (ddPCR)...
September 13, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28899375/erratum-to-development-and-testing-of-a-mobile-application-to-support-diabetes-self-management-for-people-with-newly-diagnosed-type-2-diabetes-a-design-thinking-case-study
#19
Mira Petersen, Nana F Hempler
No abstract text is available yet for this article.
September 12, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28898437/regulation-of-fibroblast-growth-factor-8-fgf8-in-chicken-embryonic-stem-cells-differentiation-into-spermatogonial-stem-cells
#20
Man Wang, Chen Zhang, Chuanli Huang, Shaoze Cheng, Nana He, Yilin Wang, Mahmoud F Ahmed, Ruifeng Zhao, Jing Jin, Qisheng Zuo, Yani Zhang, Bichun Li
Fibroblast growth factors (FGFs) are essential in regulating the formation of spermatogonial stem cells (SSCs). Here, we explored the effect of FGF8 on chicken SSCs formation by knockdown or overexpression of FGF8 in chicken embryonic stem cells (ESCs) both in vitro and in vivo. Our results showed that knockdown of FGF8 could facilitate the differentiation of ESCs into SSCs, overexpression of FGF8 could promote PGCs self-renewal, inhibit SSCs formation. This study further revealed the positive correlation between the expression level of FGF8 and MAPK/ERK signal...
September 12, 2017: Journal of Cellular Biochemistry
keyword
keyword
11671
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"