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hepatitis C cardiac surgery

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https://www.readbyqxmd.com/read/28446492/hepatic-fibrosis-is-universal-following-fontan-operation-and-severity-is-associated-with-time-from-surgery-a-liver-biopsy-and-hemodynamic-study
#1
David J Goldberg, Lea F Surrey, Andrew C Glatz, Kathryn Dodds, Michael L O'Byrne, Henry C Lin, Mark Fogel, Jonathan J Rome, Elizabeth B Rand, Pierre Russo, Jack Rychik
BACKGROUND: Congestive hepatopathy is a recognized complication of Fontan physiology. Data regarding the incidence of hepatopathy and risk factors are lacking. METHODS AND RESULTS: Liver biopsies and cardiac catherizations were performed as part of an evaluation offered to all patients ≥10 years after Fontan. Quantitative determination of hepatic fibrosis was performed using Sirius red staining with automated calculation of collagen deposition per slide (%CD)...
April 26, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28414673/purulent-pericarditis-due-to-an-infected-pacemaker-lead
#2
Teresa Backes
INTRODUCTION: Intravenous drug users have a substantially increased risk of infective endocarditis, especially in the setting of implanted cardiac devices. Purulent pericarditis is a rare occurrence that can occur iatrogenically or through direct or hematogenous spread. CASE DESCRIPTION: A 75 year old man with a past medical history significant for hepatitis C, IV drug abuse, and sick sinus syndrome status post pacemaker was brought in by EMS with a chief complaint of diaphoresis and chest pain...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28282660/clinical-results-of-cardiac-surgery-in-patients-with-chronic-hepatitis-c-and-their-role-in-risk-models-a-case-control-study
#3
Cagdas Baran, Mehmet Cakici, Evren Ozcinar, Serkan Durdu, Bahadir Inan, Mustafa Sirlak, Ruchan Akar
Background To evaluate the results of patients with chronic hepatitis C virus (HCV) following cardiac surgery in the TurcoSCORE (TrS) database. Methods Sixty patients with HCV who underwent cardiac surgery between 2005 and 2016 in our clinic out of a total 8,018 patients from the TrS database were included in the study. The perioperative morbidity and mortality rates in these patients were compared with a matched cohort. Results The mean follow-up time was 96.6 ± 12.3 months. Hospital mortality rates (HCV group 5% vs...
March 10, 2017: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/28217062/anesthetic-management-of-a-case-of-gilbert-s-syndrome-for-mitral-and-aortic-valve-replacement-role-of-transesophageal-echocardiography
#4
P S Nagaraja, Naveen G Singh, S Subash, N Manjunatha, C G Prabhushankar, N Sathish
Gilbert's syndrome (GS) is an autosomal inherited disorder characterized by relative deficiency of glucuronyl transferase and poor uptake of unconjugated bilirubin by hepatocytes. Cardiac surgery on cardiopulmonary bypass (CPB) in these patients triggers further hepatic dysfunction. Transesophageal echocardiography (TEE) and Doppler assessment of hepatic vein help in assessing hepatic blood flow (HBF) during cardiac surgery. Here, we discuss anesthetic management and role of TEE in maintaining HBF perioperatively in a 25-year-old male patient with GS undergoing double valve replacement with tricuspid valve plasty...
January 2017: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/28151809/liver-transplantation-around-the-world
#5
James F Trotter
PURPOSE OF REVIEW: In the past few years, there have been important changes in the development of liver transplantation around the world. In particular, several emerging countries have rapidly developed transplant programs. There have also been important changes in liver allocation, utilization of donors by cardiac death, and living donors. A review of the practices in different countries around the world will help provide the reader with a better appreciation of their own program as well as the recognition of potential areas of improvement based on the experience of their colleagues...
February 1, 2017: Current Opinion in Organ Transplantation
https://www.readbyqxmd.com/read/28091794/the-impact-of-liver-disorders-on-perioperative-management-of-reoperative-cardiac-surgery-a-retrospective-study-in-adult-congenital-heart-disease-patients
#6
Koko Adachi, Hiroaki Toyama, Yu Kaiho, Osamu Adachi, Hiroto Hudeta, Masanori Yamauchi
PURPOSE: We evaluated the preoperative prevalence of risk factors for liver disorders and the relationship between the liver disorders and perioperative outcomes in adult congenital heart disease (ACHD) patients. METHODS: This retrospective study included 32 ACHD patients who underwent reoperative cardiac surgery. RESULTS: Preoperatively, 38% of the study patients had risk factors, including congestive liver (CL) due to right heart failure (31%), chronic hepatitis C (HC) (22%), and both CL and HC (16%)...
January 16, 2017: Journal of Anesthesia
https://www.readbyqxmd.com/read/27819646/from-laparoscopic-cholecystectomy-to-liver-transplantation-when-the-gallbladder-becomes-the-pandora-s-box
#7
Georgios C Sotiropoulos, Peter Tsaparas, Stylianos Kykalos, Nikolaos Machairas, Ernesto P Molmenti, Andreas Paul
Bile duct injuries (BDI) tend to be more complex in laparoscopic than in open cholecystectomy procedures, and frequently involve young adults with benign pathologies. The ultimate consequence may be a liver transplantation (LT), making this situation one of the most rare transplant indications. Fatal post-transplant outcome is extreme infrequently reported. Aim of this study is to report on our single-case experience and to review the literature concerning lethal outcome after LT for major BDI following cholecystectomy...
2016: Chirurgia
https://www.readbyqxmd.com/read/27771699/cardiac-hepcidin-expression-associates-with-injury-independent-of-iron
#8
G Fenna van Breda, Lennart G Bongartz, Wenqing Zhuang, Rachel P L van Swelm, Jeanne Pertijs, Branko Braam, Maarten-Jan Cramer, Dorine W Swinkels, Pieter A Doevendans, Marianne C Verhaar, Roos Masereeuw, Jaap A Joles, Carlo A J M Gaillard
BACKGROUND: Hepcidin regulates systemic iron homeostasis by downregulating the iron exporter ferroportin. Circulating hepcidin is mainly derived from the liver but hepcidin is also produced in the heart. We studied the differential and local regulation of hepcidin gene expression in response to myocardial infarction (MI) and/or chronic kidney disease (CKD). We hypothesized that cardiac hepcidin gene expression is induced by and regulated to severity of cardiac injury, either through direct (MI) or remote (CKD) stimuli, as well as through increased local iron content...
2016: American Journal of Nephrology
https://www.readbyqxmd.com/read/27077830/regarding-high-risk-cardiac-surgery-in-patients-with-intravenous-drug-abuse-and-or-active-hepatitis-c-or-human-immunodeficiency-virus-infection-an-ethical-discussion-of-six-cases
#9
Maurizio Domanin, Giovanni Romagnoni
No abstract text is available yet for this article.
January 2017: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/27016196/renal-cell-carcinoma-with-thrombus-extending-to-the-hepatic-veins-or-right-atrium-operative-strategies-based-on-41-consecutive-patients
#10
Maude Gagné-Loranger, Louis Lacombe, Frédéric Pouliot, Vincent Fradet, François Dagenais
OBJECTIVES: The natural history of renal cell carcinoma (RCC) with tumour thrombus extending at or above the hepatic veins is dismal. Different surgical approaches have been described including cardiopulmonary bypass (CPB) with deep hypothermic circulatory arrest. We here report our experience in terms of surgical techniques and outcomes on 41 consecutive patients presenting an RCC extending to the hepatic veins or the right atrium. A surgical decision-making algorithm is discussed. METHODS: Retrospective review of 41 patients operated for RCC extending in the retrohepatic vena cava (extent level III-IV) between 2000 and 2015...
August 2016: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/26927939/risk-factors-for-longer-hospital-stay-following-the-fontan-operation
#11
Jun Sasaki, John C Dykes, Lisa J Sosa, Jane L Salvaggio, Milagros D Tablante, Jorge Ojito, Danyal M Khan, Robert L Hannan, Anthony F Rossi, Redmond P Burke, Gil Wernovsky
OBJECTIVES: Children with functional single ventricle undergoing the Fontan operation consume considerable resources. The purpose of this study is to evaluate pre- and intraoperative risk factors for longer hospital stay and to describe the perioperative course at a single institution over a 15-year period. DESIGN: Retrospective cohort study. SETTING: A single pediatric cardiac ICU. PATIENTS: All consecutive patients undergoing a first-time Fontan operation from 2000 to 2014...
May 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/26837480/clinical-outcomes-of-patients-with-severe-hepatic-hereditary-hemorrhagic-telangiectasia-after-banding-of-the-hepatic-artery-and-banding-ligation-of-branches-of-the-hepatic-artery
#12
Z-C Liu, X-F Lu, H Yang, H-D Liu, X Song, S-L Ning, Y-F Xu, Y-X Chen
OBJECTIVE/BACKGROUND: To evaluate the effectiveness of double banding/ligation of hepatic arteries in treating patients with hepatic hereditary hemorrhagic telangiectasia (HHHT). METHODS: From January 2004 to December 2013, 35 patients were diagnosed with HHHT, among whom 11 woman and two men with a mean ± SD age of 44 ± 9 years were treated by double hepatic artery banding/ligation for cardiac insufficiency and/or portal hypertension. The outcomes were evaluated prospectively by measuring clinical manifestations, imaging features, liver and cardiac function, pulmonary arterial systolic pressure, and post-operative complications...
April 2016: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/26826713/cardiac-surgery-for-infective-endocarditis-in-patients-with-intravenous-drug-use
#13
Oda Bratland Østerdal, Pirjo-Riitta Salminen, Stina Jordal, Haakon Sjursen, Øystein Wendelbo, Rune Haaverstad
OBJECTIVES: Intravenous drug users have a high risk of infective endocarditis and reduced survival. Cardiac surgery may be recommended for these patients, but redo surgery is controversial. This study describes the characteristics and outcomes of intravenous drug users accepted for surgery during a 12-year period. METHODS: This retrospective study included 29 injecting drug users treated with valve surgery for endocarditis between January 2001 and December 2013 at a tertiary academic centre...
May 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/26501700/efficacy-and-safety-of-glutamine-supplemented-parenteral-nutrition-in-surgical-icu-patients-an-american-multicenter-randomized-controlled-trial
#14
RANDOMIZED CONTROLLED TRIAL
Thomas R Ziegler, Addison K May, Gautam Hebbar, Kirk A Easley, Daniel P Griffith, Nisha Dave, Bryan R Collier, George A Cotsonis, Li Hao, Traci Leong, Amita K Manatunga, Eli S Rosenberg, Dean P Jones, Gregory S Martin, Gordon L Jensen, Harry C Sax, Kenneth A Kudsk, John R Galloway, Henry M Blumberg, Mary E Evans, Paul E Wischmeyer
OBJECTIVE: To determine whether glutamine (GLN)-supplemented parenteral nutrition (PN) improves clinical outcomes in surgical intensive care unit (SICU) patients. SUMMARY BACKGROUND DATA: GLN requirements may increase with critical illness. GLN-supplemented PN may improve clinical outcomes in SICU patients. METHODS: A parallel-group, multicenter, double-blind, randomized, controlled clinical trial in 150 adults after gastrointestinal, vascular, or cardiac surgery requiring PN and SICU care...
April 2016: Annals of Surgery
https://www.readbyqxmd.com/read/26431925/hemodynamic-impact-of-superior-vena-cava-placement-in-the-y-graft-fontan-connection
#15
Maria Restrepo, A Colleen Crouch, Christopher M Haggerty, Jarek Rossignac, Timothy C Slesnick, Kirk R Kanter, Ajit P Yoganathan
BACKGROUND: A Fontan Y-shaped graft using a commercially available aortoiliac graft has been used to connect the inferior vena cava (IVC) to the pulmonary arteries. This modification of the Fontan procedure seeks to improve hepatic flow distribution (HFD) to the lungs. However, patient-specific anatomical restrictions might limit the space available for graft placement. Altering the superior vena cava (SVC) positioning is hypothesized to provide more space for an optimal connection, avoiding caval flow collision...
January 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/26420740/drainage-of-the-left-hepatic-vein-into-the-coronary-sinus-a-rare-intraoperative-finding
#16
Wouter G Morshuis, Robert A F de Lind van Wijngaarden, Charles Kik, Ad J J C Bogers
In a 76-year-old female undergoing coronary artery bypass surgery, a persistent left hepatic vein was observed. Draining of this vein into the coronary sinus is an extremely rare embryological malformation and this is the first case to be reported as a solitary malformation in absence of other cardiac malformations.
November 2015: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/26221885/prevalence-of-post-operative-morbidity-risk-factors-following-cardiac-surgery-in-patients-with-chronic-viral-hepatitis-a-retrospective-study
#17
W C Hsieh, P C Chen, G George, G Tinica, F-C Corciova
OBJECTIVE: Current cardiac risk assessments such as EuroSCORE II and the STS-Score do not take liver dysfunction into account. The purpose of this study was to evaluate the prevalence and post-operative morbidity risk factors following cardiac surgery of patients with chronic viral hepatitis. PATIENTS AND METHODS: The study group consisted of 105 patients with documented chronic viral hepatitis who were subject to elective cardiac surgery from 2001 to 2012. Subjects were evaluated for pre-operative liver dysfunction according to the MELD score...
2015: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/26030119/high-risk-cardiac-surgery-in-patients-with-intravenous-drug-abuse-and-or-active-hepatitis-c-or-hiv-infection-an-ethical-discussion-of-six-cases
#18
Laura Sophie Gansera, Edgar Eszlari, Oliver Deutsch, Walter Benno Eichinger, Brigitte Gansera
OBJECTIVES: To discuss the dilemma of adequate decision making in patients with intravenous drug abuse and recurrent valve prosthesis infections or in patients with positive HIV or hepatitis C status. Ethical, social, and economic considerations, not only in terms of technical feasibility but also in terms of unpromising results and aspects of resources, are discussed. Thoughts are presented about the legitimation of cardiac surgery centers refusing to perform surgery in high-risk patients with HIV or hepatitis C infections...
January 2016: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/25905721/safety-of-intracoronary-infusion-of-20-million-c-kit-positive-human-cardiac-stem-cells-in-pigs
#19
Matthew C L Keith, Xian-Liang Tang, Yukichi Tokita, Qian-Hong Li, Shahab Ghafghazi, Joseph Moore Iv, Kyung U Hong, Brandon Elmore, Alok Amraotkar, Brian L Ganzel, Kendra J Grubb, Michael P Flaherty, Gregory Hunt, Bathri Vajravelu, Marcin Wysoczynski, Roberto Bolli
BACKGROUND: There is mounting interest in using c-kit positive human cardiac stem cells (c-kit(pos) hCSCs) to repair infarcted myocardium in patients with ischemic cardiomyopathy. A recent phase I clinical trial (SCIPIO) has shown that intracoronary infusion of 1 million hCSCs is safe. Higher doses of CSCs may provide superior reparative ability; however, it is unknown if doses >1 million cells are safe. To address this issue, we examined the effects of 20 million hCSCs in pigs. METHODS: Right atrial appendage samples were obtained from patients undergoing cardiac surgery...
2015: PloS One
https://www.readbyqxmd.com/read/25460438/cardiac-metastases-and-tumor-embolization-a-rare-sequelae-of-primary-undifferentiated-liver-sarcoma
#20
Monica M Dua, Jordan M Cloyd, Francois Haddad, Ramin E Beygui, Jeffrey A Norton, Brendan C Visser
INTRODUCTION: Primary hepatic sarcomas are uncommon malignant neoplasms; prognostic features, natural history, and optimal management of these tumors are not well characterized. PRESENTATION OF CASE: This report describes the management of a 51-year-old patient that underwent a right trisectionectomy for a large hepatic mass found to be a liver sarcoma on pathology. He subsequently developed tumor emboli to his lungs and was discovered to have cardiac intracavitary metastases from his primary tumor...
2014: International Journal of Surgery Case Reports
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