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https://www.readbyqxmd.com/read/29342292/clinical-utility-of-the-global-anti-phospholipid-syndrome-score-for-risk-stratification-a-pooled-analysis
#1
Savino Sciascia, Massimo Radin, Giovanni Sanna, Irene Cecchi, Dario Roccatello, Maria Laura Bertolaccini
Objective: Recently, our group conceived a risk score for clinical manifestations of APS (the global APS score, or GAPSS) that takes into account the combination of independent cardiovascular risk factors and the aPL positivity profile. These include hyperlipidaemia, arterial hypertension, aCL, anti-β2 glycoprotein-I, aPS-PT and the LA. A complementary version, the adjusted GAPSS (aGAPSS), which excludes aPS-PT, was also designed. The aim of our study was to systematically review the literature to assess the clinical utility of the GAPSS and aGAPSS for risk stratification of any APS clinical manifestation...
January 12, 2018: Rheumatology
https://www.readbyqxmd.com/read/29340745/a-6-week-warm-up-injury-prevention-programme-results-in-minimal-biomechanical-changes-during-jump-landings-a-randomized-controlled-trial
#2
Jeffrey B Taylor, Kevin R Ford, Randy J Schmitz, Scott E Ross, Terry A Ackerman, Sandra J Shultz
PURPOSE: To examine the extent to which an ACL injury prevention programme modifies lower extremity biomechanics during single- and double-leg landing tasks in both the sagittal and frontal plane. It was hypothesized that the training programme would elicit improvements in lower extremity biomechanics, but that these improvements would be greater during a double-leg sagittal plane landing task than tasks performed on a single leg or in the frontal plane. METHODS: Ninety-seven competitive multi-directional sport athletes that competed at the middle- or high-school level were cluster randomized into intervention (n = 48, age = 15...
January 16, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29338824/effects-of-preoperative-isokinetic-eccentric-training-and-whey-protein-isolate-supplement-on-quadriceps-strength-and-knee-function-in-patients-with-anterior-cruciate-ligament-rupture
#3
Xiao Yuan Zhang, Hong Shi Huang, Jie Yang, Yuan Yuan Yu, Dong Xia Zhang, Cui Qing Chang
Objective To explore the effect of preoperative isokinetic eccentric training with or not whey protein isolate supplement before operation on lower limb muscle strength and knee function in patients with anterior cruciate ligament (ACL) rupture. Methods A total of 22 male volunteers aged 18-40 years with ACL rupture were recruited in outpatient service. With randomized block design,subjects were randomly assigned to isokinetic eccentric training (IE) group and isokinetic eccentric training with whey protein isolate supplement (IE+WPI) group...
December 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/29337596/the-influence-of-graft-fixation-methods-on-revision-rates-after-primary-anterior-cruciate-ligament-reconstruction
#4
Niclas H Eysturoy, Kåre Amtoft Nissen, Torsten Nielsen, Martin Lind
BACKGROUND: The method of graft fixation in primary anterior cruciate ligament (ACL) reconstruction is important for initial stability of the graft. Poor graft fixation can result in failure of the reconstruction. The effect of ACL graft fixation principles and fixation implant combinations on the risk of revision after ACL reconstruction is not well understood. PURPOSE: The study aimed to compare the risk of revision among 4 categories of femoral fixation divided by their principle of function using a hamstring tendon (HT) graft only...
January 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29334862/the-effects-of-an-unanticipated-side-cut-on-lower-extremity-kinematics-and-ground-reaction-forces-during-a-drop-landing
#5
Jae P Yom, Tane Owens, Scott Arnett, Justin Beebe, Veronica Son
Unanticipated direction to cut after landing may alter the lower extremity landing biomechanics when performing landing motions. These alterations may potentially increase the risk of ACL injury. The purpose of this study was to determine if an unanticipated side-cut affects lower extremity landing biomechanics in females. Eighteen recreational female athletes participated in two blocks of testing: the first block of testing consisted of three acceptable trials of anticipated dominant limb and non-dominant limb 45-degree diagonal cutting after landing, which were performed in a counterbalanced order...
January 16, 2018: Sports Biomechanics
https://www.readbyqxmd.com/read/29332225/over-90%C3%A2-of-children-and-adolescents-return-to-sport-after-anterior-cruciate-ligament-reconstruction-a-systematic-review-and-meta-analysis
#6
REVIEW
Jeffrey Kay, Muzammil Memon, Robert G Marx, Devin Peterson, Nicole Simunovic, Olufemi R Ayeni
PURPOSE: To evaluate the rate at which children and adolescent athletes return to sporting activities after anterior cruciate ligament (ACL) reconstruction. METHODS: Three databases, PubMed, MEDLINE, and EMBASE, were searched from database inception until September 9, 2017 by two reviewers independently and in duplicate. The inclusion criteria were English language studies that reported return to sport outcomes. Book chapters, conference papers, review articles, and technical reports were excluded...
January 13, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29331995/infographic-trends-in-paediatric-and-adolescent-acl-injuries
#7
Louise Shaw, Caroline F Finch, Sheree Bekker
No abstract text is available yet for this article.
January 13, 2018: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/29331994/acl-and-meniscal-injuries-increase-the-risk-of-primary-total-knee-replacement-for-osteoarthritis-a-matched-case-control-study-using-the-clinical-practice-research-datalink-cprd
#8
Tanvir Khan, Abtin Alvand, Daniel Prieto-Alhambra, David J Culliford, Andrew Judge, William F Jackson, Brigitte E Scammell, Nigel K Arden, Andrew James Price
OBJECTIVES: The aim of this study was to investigate whether ACL injury (ACLi) or meniscal injury increases the risk of end-stage osteoarthritis (OA) resulting in total knee replacement (TKR). METHODS: A matched case-control study of all TKRs performed in the UK between January 1990 and July 2011 and recorded in the Clinical Practice Research Datalink (CPRD) was undertaken. The CPRD contains longitudinal data on approximately 3.6 million patients. Two controls were selected for each case of TKR, matched on age, sex and general practitioner location as a proxy for socioeconomic status...
January 13, 2018: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/29329889/exploring-individual-adaptations-to-an-anterior-cruciate-ligament-injury-prevention-programme
#9
Aaron S Fox, Jason Bonacci, Scott G McLean, Natalie Saunders
BACKGROUND: Individual responses to anterior cruciate ligament injury prevention programmes (ACL IPPs) have received little attention. This study examined the effects of an ACL IPP on neuromuscular control and lower limb biomechanics during landing at the group and individual levels. METHODS: Sixteen female athletes were randomly allocated to training (n=8) or control (n=8) groups. Electromyography, and three-dimensional kinematic and kinetic data were collected during landing at two testing sessions...
January 9, 2018: Knee
https://www.readbyqxmd.com/read/29329888/associations-between-cartilage-proteoglycan-density-and-patient-outcomes-12months-following-anterior-cruciate-ligament-reconstruction
#10
Brian Pietrosimone, Daniel Nissman, Darin A Padua, J Troy Blackburn, Matthew S Harkey, Robert A Creighton, Ganesh M Kamath, Kaitlin Healy, Randy Schmitz, Jeffrey B Driban, Steve W Marshall, Joanne M Jordan, Jeffrey T Spang
BACKGROUND: Lower proteoglycan density (PGD) of the articular cartilage may be an early marker of osteoarthritis following anterior cruciate ligament (ACL) reconstruction (ACL-R). The purpose this study was to determine associations between the Knee Injury and Osteoarthritis Outcomes Score (KOOS) and PGD of the articular cartilage in the femur and tibia 12-months following ACL-R. METHODS: We evaluated KOOS pain, symptoms, function in activities of daily living (ADL), function in sport and recreation (Sport), and quality of life (QOL), as well as PGD using T1rho magnetic resonance imaging in 18 individuals 12...
January 9, 2018: Knee
https://www.readbyqxmd.com/read/29327544/-clinical-outcome-of-arthroscopic-anterior-cruciate-ligament-remnant-preserving-reconstruction
#11
Min Wei, Juan-Li Zhu, Yang Liu
OBJECTIVE: To evaluate the clinical outcome of arthroscopic anterior cruciate ligament(ACL)reconstruction with remnant cuff preservation. METHODS: There were 42 cases of ACL tear were performed reconstruction in our department from January 2012 to December 2014. The patients were 28.4 years old on average, 17 males and 25 females. ACL reconstruction was performed under arthroscopy with remnant cuff preservation. The stability of knee was assessed by Lachman test and anterior drawer test...
January 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29322055/the-pcr-rflp-based-detection-and-identification-of-the-leishmania-species-causing-human-cutaneous-leishmaniasis-in-the-khorasan-razavi-province-northeast-of-iran
#12
Anita Mohammadiha, Abdolhossein Dalimi, Mohammad Reza Mahmoodi, Mehdi Parian, Majid Pirestani, Mehdi Mohebali
Background: Leishmania tropica, the causative agent of anthroponotic cutaneous leishmaniasis (ACL), and Leishmania major, which causes zoonotic cutaneous leishmaniasis (ZCL), are endemic in Iran. Methods: Cross-sectional study was designed to identify Leishmania species in cutaneous leishmaniasis patients who referred to Mashhad Health Centers from 2013 to 2014 using ITS-PCR-RFLP technique. First, physical examinations were performed in all suspected patients and CL cases were confirmed with microscopical examinations...
September 2017: Journal of Arthropod-borne Diseases
https://www.readbyqxmd.com/read/29321670/clinical-and-experimental-evidence-suggest-a-link-between-kif7-and-c5orf42-related-ciliopathies-through-sonic-hedgehog-signaling
#13
Reza Asadollahi, Justin E Strauss, Martin Zenker, Oliver Beuing, Simon Edvardson, Orly Elpeleg, Tim M Strom, Pascal Joset, Dunja Niedrist, Christine Otte, Beatrice Oneda, Paranchai Boonsawat, Silvia Azzarello-Burri, Deborah Bartholdi, Michael Papik, Markus Zweier, Cordula Haas, Arif B Ekici, Alessandra Baumer, Eugen Boltshauser, Katharina Steindl, Michael Nothnagel, Albert Schinzel, Esther T Stoeckli, Anita Rauch
Acrocallosal syndrome (ACLS) is an autosomal recessive neurodevelopmental disorder caused by KIF7 defects and belongs to the heterogeneous group of ciliopathies related to Joubert syndrome (JBTS). While ACLS is characterized by macrocephaly, prominent forehead, depressed nasal bridge, and hypertelorism, facial dysmorphism has not been emphasized in JBTS cohorts with molecular diagnosis. To evaluate the specificity and etiology of ACLS craniofacial features, we performed whole exome or targeted Sanger sequencing in patients with the aforementioned overlapping craniofacial appearance but variable additional ciliopathy features followed by functional studies...
January 10, 2018: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/29320786/imaging-of-ligamentous-structures-within-the-knee-includes-much-more-than-the-acl
#14
Kara Gaetke-Udager, Corrie M Yablon
Ligamentous structures of the knee are numerous and complex, including the anterior and posterior cruciate ligaments, medial and lateral collateral ligaments, ligaments of the posteromedial and posterolateral corners, and the anterolateral ligament. Clinical assessment after a knee injury is paramount and can direct both the clinician's choice of imaging study and the radiologist's interpretation. Imaging is crucial in that it provides additional information for diagnosis, management, and surgical planning...
January 10, 2018: Journal of Knee Surgery
https://www.readbyqxmd.com/read/29319735/tibial-tunnel-enlargement-and-joint-instability-after-anterior-cruciate-ligament-reconstruction-a-prospective-comparison-between-autograft-and-allograft
#15
Qiang Zhang, Guangliang Hao, Mingyong Gu, Xuecheng Cao
PURPOSE: To investigate tibial tunnel widening and knee instability after ACL reconstruction with hamstring autograft or irradiated soft tissue allograft. METHODS: Eight-two patients were divided into two groups: autograft group and allograft group. Radiographic and clinical evaluations were performed. RESULTS: Seventy patients were followed up with median of 36.3 months (range 36-38 months). Tibial tunnel widening was at or greater than 30% for nine patients in the autograft group and 15 patients in the allograft group (P = 0...
December 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/29318179/preoperative-ultrasonography-is-unreliable-in-predicting-hamstring-tendon-graft-diameter-for-acl-reconstruction
#16
Amit M Momaya, Clint Beicker, Paul Siffri, Michael J Kissenberth, Jeffrey Backes, Lane Bailey, Gabriel J Rulewicz, Jennifer M Mercuri, E Carlisle Shealy, John M Tokish, Charles A Thigpen
Background: Hamstring autograft size <8 mm has been shown to be a predictor for failure after anterior cruciate ligament (ACL) reconstruction. The ability to predict graft size preoperatively is helpful in counseling patients about the possible need for graft augmentation. Purpose: To determine whether preoperative ultrasound (US) measurements of hamstring tendons can predict intraoperative graft diameter during ACL reconstruction. Study Design: Cohort study (diagnosis); Level of evidence, 2...
January 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29318174/sagittal-plane-hip-knee-and-ankle-biomechanics-and-the-risk-of-anterior-cruciate-ligament-injury-a-prospective-study
#17
Mari Leppänen, Kati Pasanen, Tron Krosshaug, Pekka Kannus, Tommi Vasankari, Urho M Kujala, Roald Bahr, Jarmo Perttunen, Jari Parkkari
Background: Stiff landings with less knee flexion and high vertical ground-reaction forces have been shown to be associated with an increased risk of anterior cruciate ligament (ACL) injury. The literature on the association between other sagittal plane measures and the risk of ACL injuries with a prospective study design is lacking. Purpose: To investigate the relationship between selected sagittal plane hip, knee, and ankle biomechanics and the risk of ACL injury in young female team-sport athletes...
December 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29318172/clinical-factors-that-predict-a-second-acl-injury-after-acl-reconstruction-and-return-to-sport-preliminary-development-of-a-clinical-decision-algorithm
#18
Mark V Paterno, Bin Huang, Staci Thomas, Timothy E Hewett, Laura C Schmitt
Background: Biomechanical predictors of a second anterior cruciate ligament (ACL) injury after ACL reconstruction (ACLR) and return to sport (RTS) have been identified; however, these measures may not be feasible in a standard clinical environment. Purpose/Hypothesis: The purpose of this study was to evaluate whether standard clinical measures predicted the risk of second ACL injuries. The hypothesis tested was that a combination of strength, function, and patient-reported measures at the time of RTS would predict the risk of second ACL injuries with high sensitivity and specificity...
December 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29318171/mobile-web-based-follow-up-for-postoperative-acl-reconstruction-a-single-center-experience
#19
James Higgins, John Semple, Lucas Murnaghan, Sarah Sharpe, John Theodoropoulos
Background: The initial 6 weeks after surgery has been identified as an area for improvement in patient care. During this period, the persistence of symptoms that go unchecked can lead to unscheduled emergency room and clinic visits, calls to surgeons' offices, and readmissions. Purpose: To analyze postoperative data from a previous study examining postoperative outcomes in 2 patient populations following breast reconstruction and anterior cruciate ligament (ACL) reconstruction with use of a patient-centered mobile application...
December 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29317879/clinical-features-of-anthroponotic-cutaneous-leishmaniasis-in-a-major-focus-southeastern-iran-1994-2014
#20
Ahmad Khosravi, Iraj Sharifi, Alireza Fekri, Alireza Kermanizadeh, Mehdi Bamorovat, Mahshid Mostafavi, Mohammad Reza Aflatoonian, Alireza Keyhani
Background: Cutaneous leishmaniasis (CL) is associated with a broad and complex clinical spectrum of diseases. The objectives of this study were to assess the clinical features and identification of the causative agents of CL in a well-known focus of anthroponotic CL (ACL) caused by Leishmania tropica, southeast Iran. Methods: This study was performed randomly as a descriptive cross-sectional survey to evaluate 2000 CL patients by active and passive case-detection approaches in Kerman Province from 1994 to 2014...
October 2017: Iranian Journal of Parasitology
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