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https://www.readbyqxmd.com/read/28550815/selection-for-intramuscular-fat-and-lean-meat-yield-will-improve-the-bloomed-colour-of-australian-lamb-loin-meat
#1
H B Calnan, R H Jacob, D W Pethick, G E Gardner
The colour of bloomed m. longissimus was measured 24h post slaughter for 8165 lamb carcasses produced over 5years across 8 sites in Australia. Intramuscular fat across a 2 to 8% range and shortloin fat weight were positively associated with meat lightness (L*), redness (a*), yellowness (b*), hue and chroma (P<0.01). Shortloin muscle weight was negatively associated with these meat colour parameters (P<0.01), although this was largely accounted for by correlated changes in intramuscular fat (P<0.01)...
May 2, 2017: Meat Science
https://www.readbyqxmd.com/read/28550799/in%C3%A2-vivo-assessment-of-dermal-adhesion-penetration-and-bioavailability-of-tetrabromobisphenol-a
#2
Yunjiang Yu, Liangzhong Li, Hongyan Li, Xiaowei Yu, Yanping Zhang, Qiong Wang, Zhixiang Zhou, Dandan Gao, Hao Ye, Bigui Lin, Ruixue Ma
Individuals are exposed to brominated flame retardants (BFRs), including tetrabromobisphenol A (TBBPA), on a daily basis because of their widespread usage. These compounds may have adverse effects on human health. In the present study, dermal absorption experiments were conducted in vivo to predict the adhesion, penetration, and bioavailability of TBBPA. TBBPA was administered to Wistar rats for 6 h by repeated dermal exposure at doses of 20, 60, 200, and 600 mg of TBBPA per kg of body weight (bw). The skin adhesion coefficient (AC) was calculated using a difference-value method and ranged from 0...
May 24, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28550786/two-giant-peritoneal-loose-bodies-were-simultaneously-found-in-one-patient-a-case-report-and-review-of-the-literature
#3
Qingxing Huang, Aihong Cao, Jun Ma, Zhenhua Wang, Jianhong Dong
INTRODUCTION: Peritoneal loose body(PLB) is usually small, therefore giant Peritoneal loose body(gPLB) with a diameter >5cm has rarely been described in the literatures. We report a case of two gPLB simultaneously found in one patient. PRESENTATION OF CASE: A healthy 79-year-old man palpated himself a solid mass with alternating localizations in his peritoneal cavity 6 months ago. It was not the complaint of frequency of urinatior until he saw the doctor a week ago...
May 18, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28550783/occurrence-distribution-and-bioaccumulation-behaviour-of-hydrophobic-organic-contaminants-in-a-large-scale-constructed-wetland-in-singapore
#4
Qian Wang, Barry C Kelly
This study involved a field-based investigation to assess the occurrence, distribution and bioaccumulation behaviour of hydrophobic organic contaminants in a large-scale constructed wetland. Samples of raw leachate, water and wetland plants, Typha angustifolia, were collected for chemical analysis. Target contaminants included polychlorinated biphenyls (PCBs), organochlorine pesticides (OCP), as well as several halogenated flame retardants (HFRs) and personal care products (triclosan and synthetic musks). In addition to PCBs and OCPs, synthetic musks, triclosan (TCS) and dechlorane plus stereoisomers (syn- and anti-DPs) were frequently detected...
May 20, 2017: Chemosphere
https://www.readbyqxmd.com/read/28550741/exploring-syndrome-differentiation-using-non-negative-matrix-factorization-and-cluster-analysis-in-patients-with-atopic-dermatitis
#5
Younghee Yun, Wonmo Jung, Hyunho Kim, Bo-Hyoung Jang, Min-Hee Kim, Jiseong Noh, Seong-Gyu Ko, Inhwa Choi
Syndrome differentiation (SD) results in a diagnostic conclusion based on a cluster of concurrent symptoms and signs, including pulse form and tongue color. In Korea, there is a strong interest in the standardization of Traditional Medicine (TM). In order to standardize TM treatment, standardization of SD should be given priority. The aim of this study was to explore the SD, or symptom clusters, of patients with atopic dermatitis (AD) using non-negative factorization methods and k-means clustering analysis...
May 22, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28550610/association-between-patient-centered-medical-home-capabilities-and-outcomes-for-medicare-beneficiaries-seeking-care-from-federally-qualified-health-centers
#6
Justin W Timbie, Peter S Hussey, Claude M Setodji, Amii Kress, Rosalie Malsberger, Tara A Lavelle, Mark W Friedberg, Suzanne G Wensky, Katherine D Giuriceo, Katherine L Kahn
BACKGROUND: Patient-centered medical home (PCMH) models of primary care have the potential to expand access, improve population health, and lower costs. Federally qualified health centers (FQHCs) were early adopters of PCMH models. OBJECTIVE: We measured PCMH capabilities in a diverse nationwide sample of FQHCs and assessed the relationship between PCMH capabilities and Medicare beneficiary outcomes. DESIGN: Cross-sectional, propensity score-weighted, multivariable regression analysis...
May 26, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28550595/clinical-pharmacokinetics-and-pharmacodynamics-of-colistin
#7
REVIEW
Nicolas Grégoire, Vincent Aranzana-Climent, Sophie Magréault, Sandrine Marchand, William Couet
In this review, we provide an updated summary on colistin pharmacokinetics and pharmacodynamics. Colistin is an old molecule that is frequently used as last-line treatment for infections caused by multidrug-resistant Gram-negative bacteria. Colistin is a decapeptide administered either as a prodrug, colistin methanesulfonate (CMS), when used intravenously, or as colistin sulfate when used orally. Because colistin binds to laboratory materials, many experimental issues are raised and studies on colistin can be tricky...
May 26, 2017: Clinical Pharmacokinetics
https://www.readbyqxmd.com/read/28550593/impact-of-black-soldier-fly-larval-meal-on-growth-performance-apparent-digestibility-haematological-and-blood-chemistry-indices-of-guinea-fowl-starter-keets-under-tropical-conditions
#8
P A Wallace, J K Nyameasem, G A Adu-Aboagye, S Affedzie-Obresi, E K Nkegbe, N Karbo, F Murray, W Leschen, P -O Maquart
In order to assess the impact of larval meal on guinea fowl, six iso-caloric and iso-nitrogenous diets were fed to day-old-keets ad libitum till 8 weeks of age. Water was also freely provided. The fishmeal (FM) component of the experimental diets was replaced with black soldier fly larval meal (BSFLM) in the following percentage ratios of 0-100%. Results showed that body weight gain significantly (P < 0.05) increased in all the BSFLM treatment groups compared to the control group. The final body weight of the birds at age 8 weeks differed significantly (P < 0...
May 26, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28550462/a-case-control-study-of-the-risk-factors-for-obstetric-fistula-in-tigray-ethiopia
#9
L Lewis Wall, Shewaye Belay, Tesfahun Haregot, Jonathan Dukes, Eyoel Berhan, Melaku Abreha
INTRODUCTION AND HYPOTHESIS: We tested the null hypothesis that there were no differences between patients with obstetric fistula and parous controls without fistula. METHODS: A unmatched case-control study was carried out comparing 75 women with a history of obstetric fistula with 150 parous controls with no history of fistula. Height and weight were measured for each participant, along with basic socio-demographic and obstetric information. Descriptive statistics were calculated and differences between the groups were analyzed using Student's t test, Mann-Whitney U test where appropriate, and Chi-squared or Fisher's exact test, along with backward stepwise logistic regression analyses to detect predictors of obstetric fistula...
May 26, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28550439/baseline-anthropometric-and-metabolic-parameters-correlate-with-weight-loss-in-women-1-year-after-laparoscopic-roux-en-y-gastric-bypass
#10
Sans Arnaud, Bailly Laurent, Anty Rodolphe, Sielezenef Igor, Gugenheim Jean, Tran Albert, Gual Philippe, Iannelli Antonio
BACKGROUND: In this study, we explored in a prospective cohort of morbidly obese women undergoing laparoscopic Roux-en-Y gastric bypass (LRYGP) correlations between baseline anthropometrics, metabolic parameters, resting energy expenditure (REE), body composition, and 1-year % excess body mass index loss (%EBMIL). We also investigated risk factors for insufficient %EBMIL. METHODS: One hundred three consecutive women were prospectively evaluated at baseline (age 40...
May 26, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28550386/human-sperm-toll-like-receptor-4-tlr4-mediates-acrosome-reaction-oxidative-stress-markers-and-sperm-parameters-in-response-to-bacterial-lipopolysaccharide-in-infertile-men
#11
Sana Sahnoun, Afifa Sellami, Nozha Chakroun, Malek Mseddi, Hammadi Attia, Tarek Rebai, Saloua Lassoued
PURPOSE: To study the role of Toll-like receptor 4 (TLR4) in human spermatozoa and to assess sperm parameters, oxidative stress markers, and acrosome reaction in response to the stimulation of TLR4 by its ligand, the lipopolysaccharide (LPS), as a major endotoxin of Gram-negative bacteria. METHODS: Our study was carried out in 73 sperm samples from patients undergoing semen analysis for couple infertility investigations. The studied patients were divided into three groups: normozoospermic fertile patients (n = 13), patients with abnormal and leukospermic semen (n = 13), and patients with abnormal and non-leukospermic semen (n = 47)...
May 26, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28550366/minimally-invasive-resection-of-adrenal-masses-in-infants-and-children-results-of-a-european-multi-center-survey
#12
Francesco Fascetti-Leon, Giovanni Scotton, Luca Pio, Raimundo Beltrà, Paolo Caione, Ciro Esposito, Girolamo Mattioli, Amulya K Saxena, Sabine Sarnaki, Piergiorgio Gamba
BACKGROUND: Minimal access adrenal surgery (MAAS) for adrenal pathologies is the standard for many pediatric surgical centers. However, the literature offers few reports and minimal evidence from small case series. The aim of this study was to evaluate the outcomes of pediatric MAAS through a multi-center data analysis. METHOD: Pediatric patients who underwent MAAS between January 2002 and December 2013 were retrospectively included. Data analysis was conducted using Spss software (Welch's t-test, X-square, Fisher tests, multiple regression model)...
May 26, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28550358/visualization-of-a-cam-type-femoroacetabular-impingement-while-squatting-using-image-matching-techniques-a-case-report
#13
Kensei Yoshimoto, Satoshi Hamai, Hidehiko Higaki, Hirotaka Gondoh, Yasuharu Nakashima
The in vivo assessment of the three-dimensional (3D) kinematics of the hip in patients with femoroacetabular impingement (FAI) under weight-bearing conditions has not been previously reported. We evaluated the pre- and postoperative hip kinematics of a 34-year-old man, with a cam-type FAI while squatting, using image-matching techniques with measurement of the rim-neck distance. Post-osteochondroplasty, the α-angle improved from 51.0° to 35.5° and the head-neck offset ratio from 0.04 to 0.23. Coxalgia during squatting disappeared, and the Harris Hip Score improved from 79 to 92 at 1 year post-surgery...
May 27, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28550356/orbital-malignant-lesions-in-adults-multiparametric-mr-imaging
#14
Bo Sun, Liyuan Song
PURPOSE: To assess the benefit of combining diffusion-weighted imaging and dynamic contrast-enhanced (DCE) MR imaging in the preoperative evaluation of orbital lymphoma and other malignancies in adults. MATERIALS AND METHODS: This retrospective study was institutional review board-approved and informed consent was waived. Pretreatment MR imaging was performed in 52 patients with malignant orbital lesions. Apparent diffusion coefficient (ADC) and DCE MR parameters were evaluated in 30 patients with orbital lymphoma and 22 patients with other orbital malignancies...
May 26, 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/28550342/influence-of-dietary-avocado-on-gut-health-in-rats
#15
Gunaranjan Paturi, Christine A Butts, Kerry L Bentley-Hewitt
This study investigated the impact of diets containing various levels of avocado (5, 10 and 15%) on gut health in rats fed for six weeks. Avocado-fed rats had significantly higher food intakes while their body weights remained similar to the control diet-fed rats. No significant changes in intestinal bacterial populations (ileum, cecum and colon) were found in rats fed avocado diets compared to the control diet. Ileum and colon tissues of rats fed avocado diets showed significantly higher expression of genes (β-defensin 1, mucin 3 or mucin 4) and a greater number of mucin-producing goblet cells in the colon...
May 26, 2017: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/28550313/quantification-of-hepatocellular-carcinoma-heterogeneity-with-multiparametric-magnetic-resonance-imaging
#16
Stefanie J Hectors, Mathilde Wagner, Octavia Bane, Cecilia Besa, Sara Lewis, Romain Remark, Nelson Chen, M Isabel Fiel, Hongfa Zhu, Sacha Gnjatic, Miriam Merad, Yujin Hoshida, Bachir Taouli
Tumour heterogeneity poses a significant challenge for treatment stratification. The goals of this study were to quantify heterogeneity in hepatocellular carcinoma (HCC) using multiparametric magnetic resonance imaging (mpMRI), and to report preliminary data correlating quantitative MRI parameters with advanced histopathology and gene expression in a patient subset. Thirty-two HCC patients with 39 HCC lesions underwent mpMRI including diffusion-weighted imaging (DWI), blood-oxygenation-level-dependent (BOLD), tissue-oxygenation-level-dependent (TOLD) and dynamic contrast-enhanced (DCE)-MRI...
May 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28550309/the-ppsu-plasmids-for-generating-dna-molecular-weight-markers
#17
Ryan C Henrici, Turner J Pecen, James L Johnston, Song Tan
Visualizing nucleic acids by gel electrophoresis is one of the most common techniques in molecular biology, and reference molecular weight markers or ladders are commonly used for size estimation. We have created the pPSU1 & pPSU2 pair of molecular weight marker plasmids which produce both 100 bp and 1 kb DNA ladders when digested with two common restriction enzymes. The 100 bp ladder fragments have been optimized to migrate appropriately on both agarose and native polyacrylamide, unlike many currently available DNA ladders...
May 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28550279/cinnamon-induces-browning-in-subcutaneous-adipocytes
#18
Hiu Yee Kwan, Jiahui Wu, Tao Su, Xiao-Juan Chao, Bin Liu, Xiuqiong Fu, Chi Leung Chan, Rebecca Hiu Ying Lau, Anfernee Kai Wing Tse, Quan Bin Han, Wang Fun Fong, Zhi-Ling Yu
Browning is the process of increasing the number of brite cells, which helps to increase energy expenditure and reduce obesity. Consumption of natural and non-toxic herbal extracts that possess the browning effect is an attractive anti-obesity strategy. In this study, we examined the browning effect of cinnamon extract. We found that cinnamon extract (CE) induced typical brown adipocyte multiocular phenotype in 3T3-L1 adipocytes. The treatment also increased brown adipocytes markers and reduced white adipocytes markers in the 3T3-L1 adipocytes...
May 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28550257/increasing-body-mass-index-at-midlife-is-associated-with-increased-cortical-thinning-in-alzheimer-s-disease-vulnerable-regions
#19
Marnie E Shaw, Walter P Abhayaratna, Kaarin J Anstey, Nicolas Cherbuin
Higher body mass index (BMI) at midlife is associated with greater decreases in cognitive function at older age as well as increased Alzheimer's disease (AD) risk, compared to those with normal BMI. Here, we tested whether BMI at midlife was associated with cortical thinning in brain regions known to be affected in early AD. We examined a large sample (n = 404) of midlife individuals (44-49 years) from the PATH population-based study. Individuals were scanned with magnetic resonance imaging (1.5T) on up to three occasions over eight years...
May 26, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28550198/host-derived-cd70-suppresses-murine-graft-versus-host-disease-by-limiting-donor-t-cell-expansion-and-effector-function
#20
Nicholas D Leigh, Rachel E O'Neill, Wei Du, Chuan Chen, Jingxin Qiu, Jonathan D Ashwell, Philip L McCarthy, George L Chen, Xuefang Cao
Allogeneic hematopoietic cell transplantation (allo-HCT) is a potentially curative treatment for hematologic and immunologic diseases. However, graft-versus-host disease (GVHD) may develop when donor-derived T cells recognize and damage genetically distinct normal host tissues. In addition to TCR signaling, costimulatory pathways are involved in T cell activation. CD27 is a TNFR family member expressed on T cells, and its ligand, CD70, is expressed on APCs. The CD27/CD70 costimulatory pathway was shown to be critical for T cell function and survival in viral infection models...
May 26, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
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