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Han-Mo Chiu

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https://www.readbyqxmd.com/read/29241275/correction-endoscopic-subtypes-of-colorectal-laterally-spreading-tumors-lsts-and-the-risk-of-submucosal-invasion-a-meta-analysis
#1
Roel M M Bogie, Manon H J Veldman, Luc A R S Snijders, Bjorn Winkens, Tonya Kaltenbach, Ad A M Masclee, Takahisa Matsuda, Eveline J A Rondagh, Roy Soetikno, Shinji Tanaka, Han-Mo Chiu, Silvia Sanduleanu-Dascalescu
No abstract text is available yet for this article.
December 14, 2017: Endoscopy
https://www.readbyqxmd.com/read/29231995/identification-of-risk-factors-for-neoplastic-colonic-polyps-in-young-adults-with-bloody-stool-in-comparison-with-those-without-symptom
#2
Kuan-Chih Chen, Chen-Shuan Chung, Wei-Fan Hsu, Tien-Yu Huang, Cheng-Kuan Lin, Tzong-Hsi Lee, Meng-Tzu Weng, Cheng-Ming Chiu, Li-Chun Chang, Han-Mo Chiu
BACKGROUND AND AIMS: The incidence and disease burden of colorectal cancer (CRC) in young adults were increasing. However, there was a dearth of advice on how to identify young population at risk for neoplastic colonic polyps (NCPs) and CRC. We aimed to indentify risk factors for NCPs and CRC in young adults presenting with bloody stool. METHODS: 1,496 subjects younger than 40-year-old who underwent colonoscopy due to bloody stool from 2005 to 2014 were enrolled in this retrospective study as the study group, and 1481 age and gender matched asymptomatic subjects who underwent colonoscopy for health checkup from 2011 to 2016 were enrolled as the control group at a tertiary center hospital...
December 12, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29179230/endoscopic-subtypes-of-colorectal-laterally-spreading-tumors-lsts-and-the-risk-of-submucosal-invasion-a-meta-analysis
#3
Roel M M Bogie, Manon H J Veldman, Luc A R S Snijders, Bjorn Winkens, Tonya Kaltenbach, Ad A M Masclee, Takahisa Matsuda, Eveline J A Rondagh, Roy Soetikno, Shinji Tanaka, Han-Mo Chiu, Silvia Sanduleanu-Dascalescu
Background and study aims Many studies have reported on laterally spreading tumors (LSTs), but systematic reviews of the data to determine their risk of containing submucosal invasion (SMI) are lacking. We systematically screened and analyzed the available literature to provide a more solid basis for evidence-based treatment. Methods We conducted a systematic search in PubMed, Embase, the Cochrane Library, and Scopus for published articles until July 2017. We estimated pooled prevalence or odds ratios (ORs) with 95 % confidence intervals (CIs), using random-effects models...
November 27, 2017: Endoscopy
https://www.readbyqxmd.com/read/29165788/factors-affecting-compliance-with-confirmatory-colonoscopy-after-a-positive-fecal-immunochemical-test-in-a-national-colorectal-screening-program
#4
Shao-Yi Cheng, Ming-Chieh Li, Shu-Li Chia, Kuo-Chin Huang, Tai-Yuan Chiu, Ding-Cheng Chan, Han-Mo Chiu
BACKGROUND: Screening with the fecal immunochemical test (FIT) is effective in reducing deaths from colorectal cancer (CRC). Since 2004, biennial FIT screening has been available to a target population in Taiwan as a national screening program. The objective of the current study was to identify the factors that influence willingness to undergo a confirmatory colonoscopy after a positive FIT, because related references in the published literature were scarce. METHODS: A semistructured questionnaire was based on the Health Belief Model (HBM) and a literature review...
November 22, 2017: Cancer
https://www.readbyqxmd.com/read/29095416/rolling-out-screening-volume-affecting-compliance-rate-and-waiting-time-of-fit-based-colonoscopy
#5
Hsiao-Hsuan Jen, Chen-Yang Hsu, Sam Li-Sheng Chen, Amy Ming-Fang Yen, Sherry Yueh-Hsia Chiu, Jean Ching-Yuan Fann, Yi-Chia Lee, Ming-Shiang Wu, Wen-Feng Hsu, Szu-Min Peng, Hsiu-Hsi Chen, Han-Mo Chiu
BACKGROUND AND STUDY AIMS: The population-based colorectal cancer screening program with fecal immunochemical test (FIT) from the inaugural period to the rolling-out period may create a higher demand for colonoscopies, but such a change has not been quantified. We intended to assess the change in the compliance rate and the waiting time (WT) for a colonoscopy and the associated geographic and institutional variations across the 2 periods. MATERIALS AND METHODS: Data from the Taiwanese nationwide colorectal cancer screening program were analyzed...
October 31, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28988890/current-status-and-future-challenge-of-population-based-organized-colorectal-cancer-screening-lesson-from-the-first-decade-of-taiwanese-program
#6
REVIEW
Ying-Wei Wang, Hsiu-Hsi Chen, Ming-Shiang Wu, Han-Mo Chiu
Colorectal cancer (CRC) is the most common cancer in Taiwan, and is the third leading cause of cancer-related death. Screening has been proven the most effective way to reduce CRC mortality, and stool-based screening is currently the most popular method of screening worldwide. In 2004, Taiwanese government launched a nationwide screening program and fecal immunochemical test (FIT) is offered biennially to individuals aged 50 to 75. The results from the program have demonstrated that FIT screening could effectively reduce the mortality from CRC...
October 5, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28799068/colorectal-cancer-screening-in-asia
#7
REVIEW
Han-Mo Chiu, Wen-Feng Hsu, Li-Chun Chang, Ming-Hsiang Wu
PURPOSE OF REVIEW: Colorectal cancer (CRC) is increasing in Asia, especially in regions with higher levels of economic development. Several Asian countries have launched population CRC screening programs to combat this devastating disease because previous studies have demonstrated that either fecal occult blood test or lower gastrointestinal endoscopy can effectively reduce CRC mortality. RECENT FINDINGS: Screening includes engaging the population, testing, administering a confirmation examination, and treating screening-detected neoplasms; thus, monitoring the whole process using measurable indicators over time is of utmost importance...
August 10, 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/28687028/adjunctive-use-of-chromoendoscopy-may-improve-the-diagnostic-performance-of-narrow-band-imaging-for-small-sessile-serrated-adenoma-polyp
#8
Li-Chun Chang, Chia-Hung Tu, Been-Ren Lin, Chia-Tung Shun, Weng-Feng Hsu, Jin-Tung Liang, Hsiu-Po Wang, Ming-Shiang Wu, Han-Mo Chiu
BACKGROUND AND AIMS: Endoscopic diagnosis of sessile serrated adenomas/polyps (SSA/P) is challenging because of their subtle appearance. Narrow-band imaging (NBI) is useful for diagnosis, but its utility with concurrent chromoendoscopy (CE), especially to detect small SSA/P, is unproven. PATIENTS AND METHODS: This prospective study enrolled 367 consecutive patients who underwent screening colonoscopy with the finding of serrated polyps. Patients were divided into derivation and validation cohorts: Diagnostic criteria using different endoscopic modalities were generated by regression analysis in the derivation cohort and were validated in the validation cohort for sensitivity, specificity, and accuracy...
July 7, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28376228/association-between-colorectal-cancer-mortality-and-gradient-fecal-hemoglobin-concentration-in-colonoscopy-noncompliers
#9
Yi-Chia Lee, Sam Li-Sheng Chen, Amy Ming-Fang Yen, Sherry Yueh-Hsia Chiu, Jean Ching-Yuan Fann, Shu-Lin Chuang, Tsung-Hsien Chiang, Chu-Kuang Chou, Han-Mo Chiu, Ming-Shiang Wu, Chien-Yuan Wu, Shu-Li Chia, Shu-Ti Chiou, Hsiu-Hsi Chen
Background: To what extent the risk for colorectal cancer (CRC) death among noncompliers of colonoscopy is elevated following positive fecal immunological testing and whether the elevated risk varies with the fecal hemoglobin concentration (f-Hb) and location of CRC have not been researched. Methods: We used data on 59 389 individuals (4.0%) among 1 489 937 Taiwanese screenees age 50 to 69 years with f-Hb 20 μg hemoglobin or more per gram of feces from 2004 to 2009...
May 1, 2017: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/28081171/a-higher-proportion-of-metabolic-syndrome-in-chinese-subjects-with-sleep-disordered-breathing-a-case-control-study-based-on-electrocardiogram-derived-sleep-analysis
#10
Ping-Huei Tseng, Pei-Lin Lee, Wei-Chung Hsu, Yan Ma, Yi-Chia Lee, Han-Mo Chiu, Yi-Lwun Ho, Ming-Fong Chen, Ming-Shiang Wu, Chung-Kang Peng
OBJECTIVE: The prevalence of metabolic syndrome (MS) has increased rapidly in Taiwan and worldwide. We aim to determine the association between sleep-disordered breathing (SDB) and MS in a Chinese general population. METHODS: This case-control study recruited subjects who have undergone a prospective electrocardiogram-based cardiopulmonary coupling (CPC) sleep spectrogram as part of the periodic health check-ups at the National Taiwan University Hospital. Comprehensive anthropometrics, blood biochemistry, prevalence of MS and its individual components were compared with Bonferroni correction between 40 subjects with SDB, defined as the CPC-derived apnea-hypopnea index (CPC-AHI) >5 event/hour and 80 age- and sex-matched controls, defined as CPC-AHI <1 event/hour...
2017: PloS One
https://www.readbyqxmd.com/read/28055109/population-based-screening-program-for-reducing-oral-cancer-mortality-in-2-334-299-taiwanese-cigarette-smokers-and-or-betel-quid-chewers
#11
Shu-Lin Chuang, William Wang-Yu Su, Sam Li-Sheng Chen, Amy Ming-Fang Yen, Cheng-Ping Wang, Jean Ching-Yuan Fann, Sherry Yueh-Hsia Chiu, Yi-Chia Lee, Han-Mo Chiu, Dun-Cheng Chang, Yann-Yuh Jou, Chien-Yuan Wu, Hsiu-Hsi Chen, Mu-Kuan Chen, Shu-Ti Chiou
BACKGROUND: To reduce oral cancer mortality, an organized, population-based screening program for the early detection of oral premalignancy and oral cancer was designed for high-risk individuals with habits of betel quid chewing, cigarette smoking, or both. The objective of this report was to evaluate the long-term effectiveness of this program in reducing the incidence of advanced disease and deaths from oral cancer. METHODS: A nationwide, population-based screening program for oral cancer has been conducted in Taiwan since 2004...
May 1, 2017: Cancer
https://www.readbyqxmd.com/read/27913699/risk-and-association-of-hla-with-oxcarbazepine-induced-cutaneous-adverse-reactions-in-asians
#12
MULTICENTER STUDY
Chun-Bing Chen, Yi-Hsin Hsiao, Tony Wu, Mo-Song Hsih, Wichittra Tassaneeyakul, Teekayu P Jorns, Chonlaphat Sukasem, Chien-Ning Hsu, Shih-Chi Su, Wan-Chun Chang, Rosaline Chung-Yee Hui, Chia-Yu Chu, Yi-Ju Chen, Ching-Ying Wu, Chao-Kai Hsu, Tsu-Man Chiu, Pei-Lun Sun, Hua-En Lee, Chin-Yi Yang, Pei-Han Kao, Chih-Hsun Yang, Hsin-Chun Ho, Jing-Yi Lin, Ya-Ching Chang, Ming-Jing Chen, Chun-Wei Lu, Chau Yee Ng, Kang-Ling Kuo, Chien-Yio Lin, Ching-Sheng Yang, Ding-Ping Chen, Pi-Yueh Chang, Tsu-Lan Wu, Yu-Jr Lin, Yi-Ching Weng, Tseng-Tong Kuo, Shuen-Iu Hung, Wen-Hung Chung
OBJECTIVE: To investigate the risk and genetic association of oxcarbazepine-induced cutaneous adverse reactions (OXC-cADRs), including Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN), in Asian populations (Chinese and Thai). METHODS: We prospectively enrolled patients with OXC-cADRs in Taiwan and Thailand from 2006 to 2014, and analyzed the clinical course, latent period, drug dosage, organ involvement, complications, and mortality. We also investigated the carrier rate of HLA-B*15:02 and HLA-A*31:01 of patients with OXC-cADRs and compared to OXC-tolerant controls...
January 3, 2017: Neurology
https://www.readbyqxmd.com/read/27696514/weo-position-statement-on-hygiene-in-digestive-endoscopy-focus-on-endoscopy-units-in-asia-and-the-middle-east
#13
Abdullah Murdani, Ajay Kumar, Han-Mo Chiu, Khean-Lee Goh, Byung Ik Jang, Christopher J L Khor, James Lau, Ibrahim Mostafa, Mohan Ramchandani, Siriporn Ratanalert, Hisao Tajiri, Minghwa Yuen, Shu Tian Zhang, Dianelle Duforest-Rey, Jean-Francois Rey
The aim of this position statement is to reinforce the key points of hygiene in digestive endoscopy. The present article details the minimum hygiene requirements for reprocessing of endoscopes and endoscopic devices, regardless of the reprocessing method (automated washer-disinfector or manual cleaning) and the endoscopy setting (endoscopy suite, operating room, elective or emergency procedures). These minimum requirements are mandatory for patient safety. Both advanced diagnostic and therapeutic endoscopies should be carried out in an environment that is safe for patients and staff...
October 1, 2016: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/27602929/controlled-dietary-restriction-with-a-prepackaged-low-residue-diet-before-colonoscopy-offers-better-quality-bowel-cleansing-and-allows-the-use-of-a-smaller-volume-of-purgatives-a-randomized-multicenter-trial
#14
RANDOMIZED CONTROLLED TRIAL
Chu-Kuang Chou, Chi-Yang Chang, Chun-Chao Chang, Li-Chun Chang, Wen-Feng Hsu, Chi-Yi Chen, Hsiu-Po Wang, Han-Mo Chiu
BACKGROUND: Bowel preparation is burdensome, and less-demanding preparation procedures are needed. Few studies have investigated the effects of low-residue diet and prepackaged low-residue diet in combination with low-volume polyethylene glycol-electrolyte lavage solution during colonoscopy preparation. OBJECTIVE: We compared self-prepared low-residue diets with prepackaged low-residue diets in combination with low-volume polyethylene glycol. DESIGN: This was a single-blinded, 3-arm, multicenter, randomized controlled trial...
October 2016: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/27498176/fecal-immunochemical-test-detects-sessile-serrated-adenomas%C3%A2-and-polyps-with-a-low-level-of-sensitivity
#15
Li-Chun Chang, Chia-Tung Shun, Weng-Feng Hsu, Chia-Hong Tu, Pei-Yu Tsai, Been-Ren Lin, Jin-Tung Liang, Ming-Shiang Wu, Han-Mo Chiu
BACKGROUND & AIMS: The serrated pathway is a distinct pathway of colorectal carcinogenesis that has been implicated in development of a substantial proportion of interval colorectal cancers. The fecal immunochemical test (FIT) detects early neoplasms with a higher level of sensitivity than the guaiac test. We investigated the sensitivity of the FIT in detection of sessile serrated adenomas/polyps (SSA/Ps). METHODS: We performed a prospective study of 6198 asymptomatic subjects (mean age, 59...
August 4, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27383100/colorectal-cancer-prevention-and-early-diagnosis-using-endoscopy
#16
Takahisa Matsuda, Masau Sekiguchi, Yasuo Kakugawa, Hiroaki Ikematsu, Yasuhiro Oono, Han-Mo Chiu, Yasushi Sano, Takahiro Fujii, Yutaka Saito
No abstract text is available yet for this article.
July 2016: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://www.readbyqxmd.com/read/27171410/outreach-and-inreach-organized-service-screening-programs-for-colorectal-cancer
#17
Chu-Kuang Chou, Sam Li-Sheng Chen, Amy Ming-Fang Yen, Sherry Yueh-Hsia Chiu, Jean Ching-Yuan Fann, Han-Mo Chiu, Shu-Lin Chuang, Tsung-Hsien Chiang, Ming-Shiang Wu, Chien-Yuan Wu, Shu-Li Chia, Yi-Chia Lee, Shu-Ti Chiou, Hsiu-Hsi Chen
BACKGROUND: Outreach (i.e., to invite those who do not use, or who under use screening services) and inreach (i.e., to invite an existing population who have already accessed the medical system) approaches may influence people to increase their use of screening test; however, whether their outcomes would be equivalent remains unclear. METHODS: A total of 3,363,896 subjects, 50-69 years of age, participated in a colorectal cancer (CRC) screening program using biennial fecal immunochemical tests; 34...
2016: PloS One
https://www.readbyqxmd.com/read/27030951/population-based-breast-cancer-screening-with-risk-based-and-universal-mammography-screening-compared-with-clinical-breast-examination-a-propensity-score-analysis-of-1%C3%A2-429%C3%A2-890-taiwanese-women
#18
Amy Ming-Fang Yen, Huei-Shian Tsau, Jean Ching-Yuan Fann, Sam Li-Sheng Chen, Sherry Yueh-Hsia Chiu, Yi-Chia Lee, Shin-Liang Pan, Han-Mo Chiu, Wen-Horng Kuo, King-Jen Chang, Yi-Ying Wu, Shu-Lin Chuang, Chen-Yang Hsu, Dun-Cheng Chang, Shing-Lang Koong, Chien-Yuan Wu, Shu-Lih Chia, Mei-Ju Chen, Hsiu-Hsi Chen, Shu-Ti Chiou
IMPORTANCE: Different screening strategies for breast cancer are available but have not been researched in quantitative detail. OBJECTIVE: To assess the benefits and the harms of risk-based and universal mammography screening in comparison with annual clinical breast examination (CBE). DESIGN: Population-based cohort study comparing incidences of stage II+ disease and death from breast cancer across 3 breast cancer screening strategies, with adjustment for a propensity score for participation based on risk factors for breast cancer and comparing the 3 strategies for overdetection between January 1999 and December 2009...
July 1, 2016: JAMA Oncology
https://www.readbyqxmd.com/read/26977757/risk-of-colorectal-neoplasia-in-individuals-with-self-reported-family-history-a-prospective-colonoscopy-study-from-16-asia-pacific-regions
#19
Martin C S Wong, Jessica Y L Ching, Han-Mo Chiu, Kai Chun Wu, Rungsun Rerknimitr, Jingnan Li, Deng-Chiang Wu, Khean Lee Goh, Takahisa Matsuda, Hyun-Soo Kim, Rupert Leong, Khay Guan Yeoh, Vui Heng Chong, Jose D Sollano, Furqaan Ahmed, Jayaram Menon, Siew C Ng, Justin C Y Wu, Francis K L Chan, Joseph J Y Sung
OBJECTIVES: We tested the hypothesis that the risk of colorectal cancer (CRC), advanced colorectal neoplasia (ACN), and colorectal adenoma among screening participants with different first-degree relatives (FDRs) affected by CRC was similar. METHODS: A multi-center, prospective colonoscopy study involving 16 Asia-Pacific regions was performed from 2008 to 2015. Consecutive self-referred CRC screening participants aged 40-70 years were recruited, and each subject received one direct optical colonoscopy...
November 2016: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/26906122/curcumin-induces-apoptosis-of-colorectal-cancer-stem-cells-by-coupling-with-cd44-marker
#20
Yu-Ting Huang, Yu-Wei Lin, Han-Mo Chiu, Been-Huang Chiang
This study investigated the effect of curcumin on colorectal cancer stem cells (CCSCs) and its possible mechanism. Comparison of the metabolic profiles of human adenomatous polyp (N = 61) and colorectal cancer (CRC) (N = 57) tissue found statistically significant differences (p < 0.05) in their composition of adenosine monophosphate (AMP), adenine, 5'-methythioadenosine, 3-hydroxybutyric acid, prostaglandin E2, threonine, and glutamine. Our cell culture model study found that curcumin treatment (50 μM for 48 h) did indeed increase apoptosis of CRC cells as well as of CCSCs, but at a significant level only in CD44(+) cells...
March 23, 2016: Journal of Agricultural and Food Chemistry
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