keyword
https://read.qxmd.com/read/38300823/association-of-subjective-and-objective-sleep-disturbance-with-the-spectrum-of-gastroesophageal-reflux-disease
#1
JOURNAL ARTICLE
Kai-Yu Hu, Ping-Huei Tseng, Wei-Chung Hsu, Pei-Lin Lee, Chia-Hung Tu, Chien-Chuan Chen, Yi-Chia Lee, Han-Mo Chiu, Ming-Shiang Wu, Chung-Kang Peng
STUDY OBJECTIVES: The relationship between obstructive sleep apnea (OSA) and gastroesophageal reflux disease (GERD) is complex. We aim to determine the association of subjective and objective sleep parameters with diverse manifestations of the GERD spectrum. METHODS: We prospectively recruited 561 subjects who underwent an electrocardiogram-based cardiopulmonary coupling (CPC) for OSA screening during a health check-up. All subjects received the Reflux Disease Questionnaire (RDQ) and an upper endoscopy to determine the presence of troublesome reflux symptoms and erosive esophagitis (EE)...
February 1, 2024: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://read.qxmd.com/read/38238704/cancer-screening-programs-in-south-east-asia-and-western-pacific
#2
JOURNAL ARTICLE
Hwee-Lin Wee, Karen Canfell, Han-Mo Chiu, Kui Son Choi, Brian Cox, Nirmala Bhoo-Pathy, Kate T Simms, Chisato Hamashima, Qianyu Shen, Brandon Chua, Niyomsri Siwaporn, Esther Toes-Zoutendijk
BACKGROUND: The burden of cancer can be altered by screening. The field of cancer screening is constantly evolving; from the initiation of program for new cancer types as well as exploring innovative screening strategies (e.g. new screening tests). The aim of this study was to perform a landscape analysis of existing cancer screening programs in South-East Asia and the Western Pacific. METHODS: We conducted an overview of cancer screening in the region with the goal of summarizing current designs of cancer screening programs...
January 18, 2024: BMC Health Services Research
https://read.qxmd.com/read/38097965/twnbiome-a-public-database-of-the-healthy-taiwanese-gut-microbiome
#3
JOURNAL ARTICLE
Amrita Chattopadhyay, Chien-Yueh Lee, Ya-Chin Lee, Chiang-Lin Liu, Hsin-Kuang Chen, Yung-Hua Li, Liang-Chuan Lai, Mong-Hsun Tsai, Yen-Hsuan Ni, Han-Mo Chiu, Tzu-Pin Lu, Eric Y Chuang
With new advances in next generation sequencing (NGS) technology at reduced costs, research on bacterial genomes in the environment has become affordable. Compared to traditional methods, NGS provides high-throughput sequencing reads and the ability to identify many species in the microbiome that were previously unknown. Numerous bioinformatics tools and algorithms have been developed to conduct such analyses. However, in order to obtain biologically meaningful results, the researcher must select the proper tools and combine them to construct an efficient pipeline...
December 14, 2023: BMC Bioinformatics
https://read.qxmd.com/read/37922999/the-evolving-landscape-of-colorectal-cancer-screening-and-colonoscopy-practice-insights-from-the-japan-polyp-study
#4
EDITORIAL
Han-Mo Chiu
No abstract text is available yet for this article.
November 1, 2023: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/37902114/navigating-changes-a-qualitative-study-exploring-the-health-related-quality-of-life-of-breast-cancer-survivors-during-the-coronavirus-disease-2019-pandemic
#5
JOURNAL ARTICLE
Ka-Huen Yip, Yuk-Chiu Yip, Wai-King Tsui, Chun-Sze Angela Chan, Yuen-Han Mo, Graeme Drummond Smith
AIMS: To explore the impact of the coronavirus disease 2019 pandemic on the health-related quality of life (HRQoL) of breast cancer survivors. DESIGN: We utilized a qualitative descriptive approach to facilitate interviews among 25 participants, all of whom are survivors of breast cancer and have received treatment in Hong Kong within the preceding 3 years. METHODS: Content analysis was performed to understand how patients' HRQoL views and experiences changed during coronavirus disease 2019 pandemic...
October 30, 2023: Journal of Advanced Nursing
https://read.qxmd.com/read/37773912/interactive-healthcare-robot-using-attention-based-question-answer-retrieval-and-medical-entity-extraction-models
#6
JOURNAL ARTICLE
Yu-Hsuan Chang, Yi-Ting Guo, Li-Chen Fu, Ming-Jang Chiu, Han-Mo Chiu, Hung-Ju Lin
In healthcare facilities, answering the questions from the patients and their companions about the health problems is regarded as an essential task. With the current shortage of medical personnel resources and an increase in the patient-to-clinician ratio, staff in the medical field have consequently devoted less time to answering questions for each patient. However, studies have shown that correct healthcare information can positively improve patients' knowledge, attitudes, and behaviors. Therefore, delivering correct healthcare knowledge through a question-answering system is crucial...
September 29, 2023: IEEE Journal of Biomedical and Health Informatics
https://read.qxmd.com/read/37463757/an-efficient-strategy-for-evaluating-new-non-invasive-screening-tests-for-colorectal-cancer-the-guiding-principles
#7
JOURNAL ARTICLE
Robert S Bresalier, Carlo Senore, Graeme P Young, James Allison, Robert Benamouzig, Sally Benton, Patrick M M Bossuyt, Luis Caro, Beatriz Carvalho, Han-Mo Chiu, Veerle M H Coupé, Willemijn de Klaver, Clasine Maria de Klerk, Evelien Dekker, Sunil Dolwani, Callum G Fraser, William Grady, Lydia Guittet, Samir Gupta, Stephen P Halloran, Ulrike Haug, Geir Hoff, Steven Itzkowitz, Tim Kortlever, Anastasios Koulaouzidis, Uri Ladabaum, Beatrice Lauby-Secretan, Mārcis Leja, Bernard Levin, Theodore Robert Levin, Finlay Macrae, Gerrit A Meijer, Joshua Melson, Colm O'Morain, Susan Parry, Linda Rabeneck, David F Ransohoff, Roque Sáenz, Hiroshi Saito, Silvia Sanduleanu-Dascalescu, Robert E Schoen, Kevin Selby, Harminder Singh, Robert J C Steele, Joseph J Y Sung, Erin Leigh Symonds, Sidney J Winawer
OBJECTIVE: New screening tests for colorectal cancer (CRC) are rapidly emerging. Conducting trials with mortality reduction as the end point supporting their adoption is challenging. We re-examined the principles underlying evaluation of new non-invasive tests in view of technological developments and identification of new biomarkers. DESIGN: A formal consensus approach involving a multidisciplinary expert panel revised eight previously established principles. RESULTS: Twelve newly stated principles emerged...
October 2023: Gut
https://read.qxmd.com/read/37381701/optimization-of-colonoscopy-quality-a-comprehensive-review-of-the-literatures-and-future-perspectives
#8
REVIEW
Wen-Feng Hsu, Han-Mo Chiu
Colonoscopy is crucial in preventing colorectal cancer (CRC) and reducing associated mortality. This comprehensive review examines the importance of high-quality colonoscopy and associated quality indicators, including bowel preparation, cecal intubation rate (CIR), withdrawal time, adenoma detection rate (ADR), complete resection, specimen retrieval, complication rates, and patient satisfaction, while also discussing other ADR-related metrics. Additionally, the review draws attention to often overlooked quality aspects, such as non-polypoid lesion detection, as well as insertion and withdrawal skills...
June 28, 2023: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://read.qxmd.com/read/37128781/editorial-optimizing-the-success-of-cold-snare-polypectomy-in-colonoscopy-practice
#9
EDITORIAL
Tiing Leong Ang, Han-Mo Chiu
No abstract text is available yet for this article.
May 2, 2023: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/37078599/double-contrast-barium-enema-is-no-longer-justified-as-a-backup-examination-for-colonoscopy-in-the-population-screening-program-population-study-in-an-organized-fecal-immunochemical-test-based-screening-program
#10
JOURNAL ARTICLE
Wen-Feng Hsu, Chiu-Wen Su, Chen-Yang Hsu, Amy Ming-Fang Yen, Sam Li-Sheng Chen, Sherry Yueh-Hsia Chiu, Yi-Chia Lee, Tsui-Hsia Hsu, Li-Ju Lin, Shu-Li Chia, Ming-Shiang Wu, Hsiu-Hsi Chen, Han-Mo Chiu
BACKGROUND AND AIM: Currently, some countries still acknowledge double-contrast barium enema (DCBE) as a backup confirmatory examination when colonoscopy is not feasible or incomplete in colorectal cancer (CRC) screening programs. This study aims to compare the performance of colonoscopy and DCBE in terms of the risk of incident CRC after negative results in the fecal immunochemical test (FIT)-based Taiwan Colorectal Cancer Screening Program. METHODS: Subjects who had positive FITs and received confirmatory exams, either colonoscopy or DCBE, without the findings of neoplastic lesions from 2004 to 2013 in the screening program comprised the study cohort...
April 20, 2023: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/37019620/joint-asian-pacific-association-of-gastroenterology-apage-asian-pacific-society-of-digestive-endoscopy-apsde-clinical-practice-guidelines-on-the-use-of-non-invasive-biomarkers-for-diagnosis-of-colorectal-neoplasia
#11
JOURNAL ARTICLE
Francis K L Chan, Martin C S Wong, Andrew T Chan, James E East, Han-Mo Chiu, Govind K Makharia, David Weller, Choon Jin Ooi, Julajak Limsrivilai, Yutaka Saito, Dao V Hang, Jon D Emery, Dadang Makmun, Kaichun Wu, Raja Affendi Raja Ali, Siew C Ng
Screening for colorectal cancer (CRC) is effective in reducing CRC related mortality. Current screening methods include endoscopy based and biomarker based approaches. This guideline is a joint official statement of the Asian Pacific Association of Gastroenterology (APAGE) and the Asian Pacific Society of Digestive Endoscopy (APSDE), developed in response to the increasing use of, and accumulating supportive evidence for the role of, non-invasive biomarkers for the diagnosis of CRC and its precursor lesions...
July 2023: Gut
https://read.qxmd.com/read/36987587/is-this-the-end-of-colonoscopy-screening-for-colorectal-cancer-an-asia-pacific-perspective
#12
EDITORIAL
Rashid N Lui, Sunny H Wong, Nik Sheng Ding, Masau Sekiguchi, Jun Yu, Tiing-Leong Ang, Khay-Guan Yeoh, Han-Mo Chiu, Joseph J Y Sung
No abstract text is available yet for this article.
March 28, 2023: Journal of Gastroenterology and Hepatology
https://read.qxmd.com/read/36802753/cold-versus-hot-snare-polypectomy-for-small-colorectal-polyps-a-pragmatic-randomized-controlled-trial
#13
RANDOMIZED CONTROLLED TRIAL
Li-Chun Chang, Chi-Yang Chang, Chi-Yi Chen, Cheng-Hao Tseng, Peng-Jen Chen, Chia-Tung Shun, Wen-Feng Hsu, Yen-Nien Chen, Chieh-Chang Chen, Tien-Yu Huang, Chia-Hung Tu, Mei-Jyh Chen, Chu-Kuang Chou, Ching-Tai Lee, Po-Yueh Chen, Ming-Shiang Wu, Han-Mo Chiu
BACKGROUND: Although cold snare polypectomy (CSP) is considered effective in reducing delayed postpolypectomy bleeding risk, direct evidence supporting its safety in the general population remains lacking. OBJECTIVE: To clarify whether CSP would reduce delayed bleeding risk after polypectomy compared with hot snare polypectomy (HSP) in the general population. DESIGN: Multicenter randomized controlled study. (ClinicalTrials.gov: NCT03373136)...
March 2023: Annals of Internal Medicine
https://read.qxmd.com/read/36765093/assessing-overdiagnosis-of-fecal-immunological-test-screening-for-colorectal-cancer-with-a-digital-twin-approach
#14
JOURNAL ARTICLE
Ting-Yu Lin, Sherry Yueh-Hsia Chiu, Ling-Chun Liao, Sam Li-Sheng Chen, Han-Mo Chiu, Tony Hsiu-Hsi Chen
Evaluating the magnitude of overdiagnosis associated with stool-based service screening for colorectal cancer (CRC) beyond a randomized controlled trial is often intractable and understudied. We aim to estimate the proportion of overdiagnosis in population-based service screening programs for CRC with the fecal immunochemical test (FIT). The natural process of overdiagnosis-embedded disease was first built up to learn transition parameters that quantify the pathway of non-progressive and progressive screen-detected cases calibrated with sensitivity, while also taking competing mortality into account...
February 10, 2023: NPJ Digital Medicine
https://read.qxmd.com/read/36740021/lower-than-normal-glycemic-levels-to-achieve-optimal-reduction-of-diabetes-risk-among-individuals-with-prediabetes-a-prospective-cohort-study
#15
JOURNAL ARTICLE
Hung-Ju Lin, Jui Wang, Po-Yuan Tseng, Li-Chen Fu, Yi-Chia Lee, Ming-Shiang Wu, Wei-Shiung Yang, Han-Mo Chiu
AIMS/HYPOTHESIS: To determine whether lower than currently accepted glycemic levels could lead to optimal risk reduction of incident diabetes among individuals with prediabetes. METHODS: We enrolled 9903 individuals with prediabetes and 16,902 individuals with normoglycemia from a prospective cohort participating health check-ups between 2006 and 2017. While classifying fasting glucose into <5.0, 5.0-5.5, and 5.6-6.9 mmol/L and postprandial glucose into <6...
March 2023: Diabetes Research and Clinical Practice
https://read.qxmd.com/read/36350092/patterning-and-doping-of-transition-metals-in-tungsten-dichalcogenides
#16
JOURNAL ARTICLE
Yung-Chang Lin, Yao-Pang Chang, Kai-Wen Chen, Tai-Ting Lee, Bo-Jiun Hsiao, Tsung-Han Tsai, Yueh-Chiang Yang, Kuang-I Lin, Kazu Suenaga, Chia-Hao Chen, Po-Wen Chiu
Substitutional transition metal doping in two-dimensional (2D) layered dichalcogenides is of fundamental importance in manipulating their electrical, excitonic, magnetic, and catalytic properties through the variation of the d-electron population. Yet, most doping strategies are spatially global, with dopants embedded concurrently during the synthesis. Here, we report an area-selective doping scheme for W-based dichalcogenide single layers, in which pre-patterned graphene is used as a reaction mask in the high-temperature substitution of the W sublattice...
November 9, 2022: Nanoscale
https://read.qxmd.com/read/36328306/linked-color-imaging-detects-more-colorectal-adenoma-and-serrated-lesions-an-international-randomized-controlled-trial
#17
JOURNAL ARTICLE
Sho Suzuki, Satimai Aniwan, Han-Mo Chiu, Kannikar Laohavichitra, Sakkarin Chirapongsathorn, Takeshi Yamamura, Chen-Ya Kuo, Naohisa Yoshida, Tiing Leong Ang, Takahito Takezawa, Rungsun Rerknimitr, Hideki Ishikawa, Takuji Gotoda
BACKGROUND & AIMS: Effects of linked-color imaging (LCI) on colorectal lesion detection and colonoscopy quality remain controversial. This study compared the detection rates of adenoma and other precursor lesions using LCI versus white-light imaging (WLI) during screening, diagnostic, and surveillance colonoscopy. METHODS: This randomized controlled trial was performed at 11 institutions in four Asian countries/regions. Patients with abdominal symptoms, primary screening colonoscopy, positive fecal immunochemical test results, or undergoing post-polypectomy surveillance were recruited and randomly assigned in a 1:1 ratio to either the LCI or high-definition WLI group...
October 31, 2022: Clinical Gastroenterology and Hepatology
https://read.qxmd.com/read/36109362/positive-and-negative-impact-of-anti-reflux-mucosal-intervention-on-gastroesophageal-reflux-disease
#18
JOURNAL ARTICLE
Chu-Kuang Chou, Chien-Chuan Chen, Chieh-Chang Chen, Jia-Feng Wu, Wei-Chih Liao, Han-Mo Chiu, Hsiu-Po Wang, Ming-Shiang Wu, Ping-Huei Tseng
BACKGROUND: Anti-reflux mucosal intervention (ARMI), including anti-reflux mucosectomy (ARMS) and anti-reflux mucosal ablation (ARMA), is a promising endoscopic treatment for gastroesophageal reflux disease (GERD). Few studies reported a detailed analysis of the objective reflux parameters. METHODS: Patients with chronic PPI-dependent GERD and receiving ARMI were prospectively enrolled. Comprehensive clinical symptom profiles, endoscopy results, and 24-h multichannel intraluminal impedance-pH (MII-pH) monitoring were collected and analyzed before and 3 months after ARMI...
September 15, 2022: Surgical Endoscopy
https://read.qxmd.com/read/36002247/third-asia-pacific-consensus-recommendations-on-colorectal-cancer-screening-and-postpolypectomy-surveillance
#19
JOURNAL ARTICLE
Joseph J Y Sung, Han-Mo Chiu, David Lieberman, Ernst J Kuipers, Matthew D Rutter, Finlay Macrae, Khay-Guan Yeoh, Tiing Leong Ang, Vui Heng Chong, Sneha John, Jingnan Li, Kaichun Wu, Simon S M Ng, Govind K Makharia, Murdani Abdullah, Nozomu Kobayashi, Masau Sekiguchi, Jeong-Sik Byeon, Hyun-Soo Kim, Susan Parry, Patricia Anne I Cabral-Prodigalidad, Deng-Chyang Wu, Suparkij Khomvilai, Rashid N Lui, Sunny Wong, Yu-Min Lin, E Dekker
The Asia-Pacific region has the largest number of cases of colorectal cancer (CRC) and one of the highest levels of mortality due to this condition in the world. Since the publishing of two consensus recommendations in 2008 and 2015, significant advancements have been made in our knowledge of epidemiology, pathology and the natural history of the adenoma-carcinoma progression. Based on the most updated epidemiological and clinical studies in this region, considering literature from international studies, and adopting the modified Delphi process, the Asia-Pacific Working Group on Colorectal Cancer Screening has updated and revised their recommendations on (1) screening methods and preferred strategies; (2) age for starting and terminating screening for CRC; (3) screening for individuals with a family history of CRC or advanced adenoma; (4) surveillance for those with adenomas; (5) screening and surveillance for sessile serrated lesions and (6) quality assurance of screening programmes...
November 2022: Gut
https://read.qxmd.com/read/35778863/implementing-precision-medicine-in-endoscopy-practice
#20
REVIEW
Chen-Ya Kuo, Jer-Wei Wu, Jen-Hao Yeh, Wen-Lun Wang, Chia-Hung Tu, Han-Mo Chiu, Wei-Chih Liao
In contrast to the "one-size-fits-all" approach, precision medicine focuses on providing health care tailored to individual variabilities. Implementing precision medicine in endoscopy practice involves selecting the appropriate procedures among the endoscopic armamentarium in the diagnosis and management of patients in a logical sequence, jointly considering the pretest probabilities of possible diagnoses, patients' comorbidities and preference, and risk-benefit ratio of the individual procedures given the clinical scenario...
August 2022: Journal of Gastroenterology and Hepatology
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