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https://www.readbyqxmd.com/read/28822641/clinical-and-radiographic-outcomes-with-assessment-of-the-learning-curve-in-arthroscopically-assisted-latissimus-dorsi-tendon-transfer-for-irreparable-posterosuperior-rotator-cuff-tears
#1
Kotaro Yamakado
PURPOSE: To evaluate the clinical results of an arthroscopy-assisted latissimus dorsi tendon transfer (aLD) for irreparable posterosuperior cuff tears as a primary surgery. The secondary aim of this study was to quantify the learning curve using the log-linear model. We hypothesized that aLD significantly improved shoulder function and that there was consistent reduction of the operative time in support of a learning-curve effect. METHODS: After the arthroscopic partial repair was completed, the latissimus dorsi tendon was harvested via axillary mini-open incision and fixed with a knotless anchor arthroscopically...
August 16, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28821939/analgesic-use-in-patients-with-knee-and-or-hip-osteoarthritis-referred-to-an-outpatient-center-a-cross-sectional-study-within-the-amsterdam-osteoarthritis-cohort
#2
Jesper Knoop, Joyce van Tunen, Martin van der Esch, Leo D Roorda, Joost Dekker, Marike van der Leeden, Willem F Lems
Although analgesics are widely recommended in current guidelines, underuse and inadequate prescription of analgesics seem to result in suboptimal treatment effects in patients with knee and/or hip osteoarthritis (OA). This study aimed (i) to describe the use of analgesics; and (ii) to determine factors that are related to analgesic use in patients with knee and/or hip OA referred to an outpatient center. A cross-sectional study with data from 656 patients with knee and/or hip OA referred to an outpatient center (Amsterdam Osteoarthritis (AMS-OA) cohort) was conducted...
August 18, 2017: Rheumatology International
https://www.readbyqxmd.com/read/28821271/high-speed-resistance-training-and-balance-training-for-people-with-knee-osteoarthritis-to-reduce-falls-risk-study-protocol-for-a-pilot-randomized-controlled-trial
#3
Pazit Levinger, Jeremy Dunn, Nancy Bifera, Michael Butson, George Elias, Keith D Hill
BACKGROUND: The number of falls experienced by people with knee osteoarthritis (OA) is almost double the number experienced by people with no OA. The neuromuscular elements required to arrest a fall are more impaired in people with knee OA compared to their asymptomatic counterparts. Therefore, these elements may need to be incorporated into an exercise intervention to reduce the risk of falling. The aim of this study will be to examine the feasibility, safety and patient satisfaction of a high-speed resistance-training program, with and without balance exercises, in people with knee OA compared to a control group...
August 18, 2017: Trials
https://www.readbyqxmd.com/read/28820428/pharmacokinetic-analysis-of-an-oral-multicomponent-joint-dietary-supplement-phycox-%C3%A2-in-dogs
#4
Stephanie E Martinez, Ryan Lillico, Ted M Lakowski, Steven A Martinez, Neal M Davies
Despite the lack of safety, efficacy and pharmacokinetic (PK) studies, multicomponent dietary supplements (nutraceuticals) have become increasingly popular as primary or adjunct therapies for clinical osteoarthritis in veterinary medicine. Phycox(®) is a line of multicomponent joint support supplements marketed for joint health in dogs and horses. Many of the active constituents are recognized anti-inflammatory and antioxidant agents. Due to a lack of PK studies in the literature for the product, a pilot PK study of select constituents in Phycox(®) was performed in healthy dogs...
August 18, 2017: Pharmaceutics
https://www.readbyqxmd.com/read/28820271/cam-deformities-and-limited-hip-range-of-motion-are-associated-with-early-osteoarthritic-changes-in-adolescent-athletes-a-prospective-matched-cohort-study
#5
Cody C Wyles, Germán A Norambuena, Benjamin M Howe, Dirk R Larson, Bruce A Levy, Brandon J Yuan, Robert T Trousdale, Rafael J Sierra
BACKGROUND: The natural history of femoroacetabular impingement (FAI) remains incompletely understood. In particular, there is limited documentation of joint damage in adolescent patients with limited range of motion (LROM) of the hip, which is commonly associated with FAI. PURPOSE: To evaluate changes in magnetic resonance imaging (MRI), radiographs, and clinical examinations over 5 years in a group of athletes from a wide variety of sports with asymptomatic LROM of the hip compared with matched controls...
August 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28819826/the-outcome-of-the-partial-resurfacing-arthroplasty-of-the-hip-shows-high-numbers-of-failures-and-conversion-to-total-arthroplasty
#6
Thilo Floerkemeier, Stefan Budde, Nils Wirries, Gabriela von Lewinski, Henning Windhagen, Marco Ezechieli
PURPOSE: Local cartilage and bony defects, which are too large for joint preserving cartilage treatment are difficult to treat. The implantation of a mini-resurfacing implant (Hemicap®, 2med, Hamburg, Germany) may be a possible alternative treatment for these patients. This partial replacement fills the defect and restores a smooth and continuous articular surface. The aim of this study was to determine short- to midterm results of the treatment of local cartilage defects of the femoral head using the Hemicap®...
August 17, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28819343/mid-term-migration-of-a-cementless-porous-acetabular-cup-a-5%C3%A2-year-radiostereometric-analysis
#7
Kjell G Nilsson, Annika Theodoulou, Graham Mercer, Stephen J Quinn, Jeganath Krishnan
PURPOSE: The aim of the study was to determine the 5 year migratory and wear patterns, adverse events and clinical outcomes of a cementless, porous acetabular cup. METHODS: RSA imaging of a cohort of 11 patients was retrospective analysed at 5 years post Total Hip Arthroplasty (THA). Changes in pain, function and symptoms of the hip at 5 years post-THA were compared to preoperative and 2 year postoperative assessments on the Harris Hip Score (HHS) and Hip dysfunction and Osteoarthritis Outcome Score (HOOS)...
December 2017: Journal of Orthopaedics
https://www.readbyqxmd.com/read/28816972/low-second-to-fourth-digit-ratio-in-dupuytren-disease
#8
Takuya Yokoi, Takuya Uemura, Kenichi Kazuki, Ema Onode, Kosuke Shintani, Mitsuhiro Okada, Hiroaki Nakamura
The ratio of the lengths of the second and fourth digits (2D:4D) has been described as reflecting endogenous prenatal androgen exposure. In general, 2D:4D is lower in men than in women and has potential as a biomarker or predictor for various diseases, athletic ability, and academic performance. Dupuytren disease has digital flexion contractures and is known to predominate in men, but the pathogenesis of the disease remains unclear. To clarify the relationships between Dupuytren disease and endogenous androgens, we performed a retrospective analysis of hand radiographs to investigate 2D:4D in Dupuytren disease...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28816897/surgical-correction-of-cam-deformity-in-association-with-femoroacetabular-impingement-and-its-impact-on-the-degenerative-process-within-the-hip-joint
#9
Paul E Beaulé, Andrew D Speirs, Helen Anwander, Gerd Melkus, Kawan Rakhra, Hanspeter Frei, Mario Lamontagne
BACKGROUND: Cam morphology in association with femoroacetabular impingement (FAI) is a recognized cause of hip pain and cartilage damage and proposed as a leading cause of arthritis. The purpose of this study was to analyze the functional and biomechanical effects of the surgical correction of the cam deformity on the degenerative process associated with FAI. METHODS: Ten male patients with a mean age of 34.3 years (range, 23.1 to 46.5 years) and a mean body mass index (and standard deviation) of 26...
August 16, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28816896/factors-associated-with-adverse-events-in-inpatient-elective-spine-knee-and-hip-orthopaedic-surgery
#10
Dov B Millstone, Anthony V Perruccio, Elizabeth M Badley, Y Raja Rampersaud
BACKGROUND: Orthopaedic procedures for degenerative musculoskeletal conditions (predominantly osteoarthritis and spinal stenosis) represent an increasing burden on the health-care system. These procedures are also associated with adverse event rates and related cost. The objective of this study was to identify risk factors for adverse events associated with orthopaedic surgeries as captured within a common clinical point-of-care system for documenting adverse events (Orthopaedic Surgical AdVerse Events Severity [OrthoSAVES] system)...
August 16, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28816769/do-psychosocial-factors-predict-muscle-strength-pain-or-physical-performance-in-patients-with-knee-osteoarthritis
#11
Isabel A C Baert, Mira Meeus, Armaghan Mahmoudian, Frank P Luyten, Jo Nijs, Sabine M P Verschueren
OBJECTIVE: The aim of this study was to examine the relationship of psychosocial factors, namely, pain catastrophizing, kinesiophobia, and maladaptive coping strategies, with muscle strength, pain, and physical performance in patients with knee osteoarthritis (OA)-related symptoms. METHODS: A total of 109 women (64 with knee OA-related symptoms) with a mean age of 65.4 years (49-81 years) were recruited for this study. Psychosocial factors were quantified by the Pain Catastrophizing Scale, Tampa Scale for Kinesiophobia, and Pain Coping Inventory...
August 14, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28816722/omega-3-fatty-acids-in-rheumatic-diseases-a-critical-review
#12
Umair Akbar, Melissa Yang, Divya Kurian, Chandra Mohan
Many clinical trials of omega-3 fatty acids, supplied as fish oil supplements, have been carried out in rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), lupus nephritis, and osteoarthritis (OA) over the past 3 decades. This review attempts to summarize the highlights of these studies to evaluate the clinical efficacy for omega-3 fatty acids to be added alongside existing treatment regimens. A total of 20 clinical trials have been carried out in RA, of which 16 exhibited significant improvements in multiple disease clinical outcomes...
August 15, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28815146/quantifying-the-relative-change-in-physical-activity-after-total-knee-arthroplasty-using-accelerometer-based-measurements
#13
Vibhu Agarwal, Mathew Smuck, Nigam H Shah
Osteoarthritis is amongst the top five most disabling conditions affecting Americans over 65 years of age and imposes an annual economic burden estimated at $ 89.1 billion. Nearly half of the cost of care of Osteoarthritis is attributable to hospitalizations for total knee arthroplasties (TKA) and total hip arthroplasties (THA). The current clinical practice relies predominantly on subjective assessment of physical function and pain via patient reported outcome measures (PROM) that have proven inadequate for providing a validated, reliable and responsive measure of TKA outcomes...
2017: AMIA Summits on Translational Science Proceedings
https://www.readbyqxmd.com/read/28811352/patient-acceptable-symptom-state-in-knee-osteoarthritis-patients-succeeds-across-different-patient-reported-outcome-measures-assessing-physical-function-but-fails-across-other-dimensions-and-rheumatic-diseases
#14
Elien A M Mahler, Nadine Boers, Johannes W J Bijlsma, Frank H J van den Hoogen, Alfons A den Broeder, Cornelia H M van den Ende
OBJECTIVE: The aims of this study are (1) to establish the Patient Acceptable Symptom State (PASS) cutoff values of different patient-reported outcome measures (PROM) assessing physical function in patients with knee osteoarthritis (OA), and (2) to assess the influence of sex, age, duration of symptoms, and presence of depressive feelings on being in PASS. METHODS: Patients fulfilling the clinical American College of Rheumatology knee OA criteria received standardized nonsurgical treatment and completed different questionnaires at baseline and 3 months assessing physical function: Knee Injury and Osteoarthritis Outcome Score, Lequesne Algofunctional Index, Lower Extremity Functional Scale, numerical rating scale, and the physical function subscale of the Western Ontario and McMaster Universities Osteoarthritis Index...
August 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28810001/deferoxamine-synergizes-with-transforming-growth-factor-%C3%AE-signaling-in-chondrogenesis
#15
Zheng Huang, Guangxu He, Yanke Huang
Osteoarthritis, also known as degenerative arthritis or degenerative joint disease, is an epidemic disease that affects millions of people worldwide. Despite extensive recent work on the cellular biology of osteoarthritis, the precise mechanisms involved are still poorly understood and there is no effective treatment for this disease. The role of transforming growth factor-beta (TGF-β) in promoting chondrogenesis and inducing the expression of cartilage-specific extracellular matrix molecules to form cartilage is well-established...
August 14, 2017: Genetics and Molecular Biology
https://www.readbyqxmd.com/read/28808631/painless-swollen-calf-muscles-of-a-75-year-old-patient-caused-by-bilateral-venous-malformations
#16
Roderick S M Piekaar, Eline W Zwitser, Paul P A Hedeman Joosten, Joris A Jansen
A 75-year-old man presented with knee pain due to medial osteoarthritis of the knee in the orthopedic outpatient clinic. Conservative treatment was started with steroid infiltration. Besides his knee complaint reported a bilateral painless swollen calf muscle without traumatic cause, and also without any pain at night, fever or medical illness. On physical examination the soleus muscle had a swollen aspect in both calfs. The skin appeared normal without deformities and the arterial pulsations were intact. An X-ray did not show abnormalities in the tibia...
July 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28808182/determination-of-serum-biomarkers-in-osteoarthritis-patients-a-previous-interventional-imaging-study-revisited
#17
Timothy McAlindon, Eckart Bartnik, Janina S Ried, Lenore Teichert, Matthias Herrmann, Klaus Flechsenhar
To evaluate in an interventional trial on knee osteoarthritis (OA) the level and change of two serum biomarkers and their correlation with imaging parameters. The previously reported interventional OA study (ClinicalTrials.gov: NCT00536302) identified a positive effect of collagen hydrolysate (CH) on cartilage morphology in patients with knee OA using delayed gadolinium enhanced magnetic resonance imaging (dGEMRIC). It was the objective in this research project to evaluate in an interventional clinical trial on knee OA the level and change of two serum biomarkers and their correlation with imaging parameters...
October 17, 2016: Journal of Biomedical Research
https://www.readbyqxmd.com/read/28807599/relationship-of-the-patient-specific-functional-scale-to-commonly-used-clinical-measures-in-hand-osteoarthritis
#18
Heidi Hermann Wright, Virginia O'Brien, Kristin Valdes, Barbra Koczan, Joy MacDermid, Elizabeth Moore, Margaret A Finley
STUDY DESIGN: Prospective cohort correlation study. INTRODUCTION: There is no known published research on correlations between the Patient-Specific Functional Scale (PSFS), hand grip strength, and the Disability of the Arm, Shoulder and Hand (DASH) in a population with hand osteoarthritis (OA). PURPOSE: The purpose of this study is to establish reliability of the PSFS and to evaluate the relationship between the PSFS, hand grip strength, and the DASH for a population with hand OA...
August 11, 2017: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
https://www.readbyqxmd.com/read/28806939/effect-of-electromagnetic-fields-on-human-osteoarthritic-and-non-osteoarthritic-chondrocytes
#19
Julia Isabelle Redeker, Bärbel Schmitt, Nele Pascale Grigull, Christian Braun, Andreas Büttner, Volkmar Jansson, Susanne Mayer-Wagner
BACKGROUND: Studies of the effects of electromagnetic fields (EMFs) on cartilaginous cells show a broad range of outcomes. However EMFs are not yet clinically applied as standard treatment of osteoarthritis, as EMF effects are showing varying outcomes in the literature. The aim of this study was to examine effects of EMFs (5 mT or 8 mT) on osteoarthritic (OA) and non-OA chondrocytes in order to investigate whether EMF effects are related to chondrocyte and EMF quality. METHODS: Pellets of human OA and non-OA chondrocytes were exposed to a sinusoidal 15 Hz EMF produced by a solenoid...
August 14, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28805094/how-balance-task-specific-training-contributes-to-improving-physical-function-in-older-subjects-undergoing-rehabilitation-following-hip-fracture-a-randomized-controlled-trial
#20
Marco Monticone, Emilia Ambrosini, Roberto Brunati, Antonio Capone, Giulia Pagliari, Claudio Secci, Giovanni Zatti, Simona Ferrante
OBJECTIVE: To evaluate the efficacy of a rehabilitation programme including balance task-specific training in improving physical function, pain, activities of daily living (ADL), balance and quality of life in subjects after a hip fracture. DESIGN: Randomized controlled trial. SUBJECTS: A total of 52 older subjects selected for internal fixation due to extra-capsular hip fracture were randomized to be included in an experimental ( n = 26) and control group ( n = 26)...
August 1, 2017: Clinical Rehabilitation
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