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Kidd system

Ryan Eyn Kidd Man, Eva K Fenwick, Charumathi Sabanayagam, Ling-Jun Li, Ching Siong Tey, Hasita Jian Tai Soon, Gemmy Chui-Ming Cheung, Gavin Siew Wei Tan, Tien Yin Wong, Ecosse L Lamoureux
PURPOSE: To evaluate and compare the impact of unilateral better-eye and bilateral categorizations of diabetic retinopathy (DR) and diabetic macular edema (DME) on vision-related quality of life (VRQoL) in individuals with type 2 diabetes (T2DM). METHODS: We recruited 390 subjects (116 females; age range, 22-78 years) of Malay, Indian, and Chinese ethnicities from the Singapore Diabetes Management Project (S-DMP), a cross-sectional clinic-based study conducted from 2010 to 2013...
September 1, 2016: Investigative Ophthalmology & Visual Science
Joana Maira Valentini Zacarias, Ieda Bernadete Volkweis Langer, Jeane Eliete Laguila Visentainer, Ana Maria Sell
The aim of this study was to assess the distribution of alleles and genotypes of the blood group systems Rh, Kell, Duffy, Kidd, and Diego in 251 regular blood donors registered in the hemotherapy unit of the Southwestern region of Paraná, Southern Brazil. The frequencies were obtained by direct counting on a spreadsheet program and statistical analyses were conducted in order to compare them with other Brazilian populations using chi-squared with Yates correction on OpenEpi software. The frequencies of RHD* negative, RHCE*c/c and RHCE*e/e were higher than expected for the Caucasian population...
August 5, 2016: Transfusion and Apheresis Science
Desmond P Kidd, Ben J Burton, Elizabeth M Graham, Gordon T Plant
OBJECTIVE: To identify and follow a series of 52 patients with optic neuropathy related to sarcoidosis. METHODS: Prospective observational cohort study. RESULTS: The disorder was more common in women and affected a wide age range. It was proportionately more common in African and Caribbean ethnic groups. Two clinical subtypes were identified: the more common was a subacute optic neuropathy resembling optic neuritis; a more slowly progressive optic neuropathy arose in the remaining 17%...
October 2016: Neurology® Neuroimmunology & Neuroinflammation
Daiane Cobianchi Costa, Alessandra Arruda Schinaider, Thais Mattos Santos, Everaldo José Schörner, Daniel Simon, Sharbel Weidner Maluf, Ana Carolina Rabello de Moraes, Maria Claudia Silva Silva
BACKGROUND: Red blood cell genes are highly polymorphic with the distribution of alleles varying between different populations and ethnic groups. The objective of this study was to investigate gene polymorphisms of blood groups in the state of Santa Catarina, Southern Brazil. METHODS: Three hundred and seventy-three unrelated blood donors and 31 transfusion-dependent patients were evaluated to investigate polymorphisms of the Rh, Kell, Duffy, Kidd, and Diego blood group systems in a population from the state of Santa Catarina...
July 2016: Revista Brasileira de Hematologia e Hemoterapia
Lei Chen, Kerry J Welsh, Brian Chang, Laura Kidd, Marylee Kott, Mohammad Zare, Kelley Carroll, Andy Nguyen, Amer Wahed, Ashok Tholpady, Norin Pung, Donna McKee, Semyon A Risin, Robert L Hunter
OBJECTIVES: Harris Health System (HHS) is a safety net system providing health care to the underserved of Harris County, Texas. There was a 6-month waiting period for a rheumatologist consult for patients with suspected systemic lupus erythematosus (SLE). The objective of the intervention was to improve access to specialty care. METHODS: An algorithmic approach to testing for SLE was implemented initially through the HHS referral center. The algorithm was further offered as a "one-click" order for physicians, with automated reflex testing, interpretation, and case triaging by clinical pathology...
September 2016: American Journal of Clinical Pathology
Andrew P Maurice, Samuel Chan, Clifford W Pollard, Richard A Kidd, Stephen J Ayre, Helen E Ward, Darren L Walters
The discharge summary (DS) is a summary of an inpatient admission, patient's health state, and future treatment plans which is delivered to the patient's primary care provider. The DS is often incomplete, inaccurate, or unclear. The aim of this project was to improve the quality of the DS through the use of an electronic prompting system. The electronic prompting system was implemented in the acute medical and surgical wards of the hospital as an adjunct to a pre-existing, widely used hospital program that documents all the patients in a ward or belonging to a particular treating team...
2014: BMJ Quality Improvement Reports
Scott W Kidd, Christopher A Preston, George E Moore
OBJECTIVE: To report postoperative complications using a commercially available porous-coated press-fit cementless total hip replacement (THR) system in dogs. METHODS: Medical records were reviewed for client-owned dogs with hip pathologies requiring THR. A minimum of six-week postoperative orthopaedic examination and orthogonal pelvic radiographs were used to assess outcome and complications in the perioperative period. Referring veterinarian medical records, phone interviews with clients, or both were used to assess long-term functional outcome and complications...
September 20, 2016: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
Stephen K Kidd, Marc P Bonaca, Eugene Braunwald, Gaetano M De Ferrari, Basil S Lewis, Piera A Merlini, Sabina A Murphy, Benjamin M Scirica, Harvey D White, David A Morrow
BACKGROUND: Our dual aims were as follows: (1) to classify new or recurrent myocardial infarctions (MI) in patients with stable atherosclerosis using the Universal Definition of MI classification system; and (2) to characterize the effects of vorapaxar, a first-in-class platelet protease-activated receptor -1 antagonist, on new or recurrent MI. METHODS AND RESULTS: We analyzed data from TRA 2°P-TIMI 50, a multinational, randomized, double-blind, placebo-controlled trial of vorapaxar...
July 2016: Journal of the American Heart Association
Graham R Johnson, Luke D Knibbs, Timothy J Kidd, Claire E Wainwright, Michelle E Wood, Kay A Ramsay, Scott C Bell, Lidia Morawska
This work aimed to develop an in vivo approach for measuring the duration of human bioaerosol infectivity. To achieve this, techniques designed to target short-term and long-term bioaerosol aging, were combined in a tandem system and optimized for the collection of human respiratory bioaerosols, without contamination. To demonstrate the technique, cough aerosols were sampled from two persons with cystic fibrosis and chronic Pseudomonas aeruginosa infection. Measurements and cultures from aerosol ages of 10, 20, 40, 900 and 2700 seconds were used to determine the optimum droplet nucleus size for pathogen transport and the airborne bacterial biological decay...
2016: PloS One
Huseyin Bilgin, Abdulkadir Eren, Semra Kara
Many different blood group systems, such as Rh, ABO, Kell, Kidd, Duffy, MNS, have been reported as causes of hemolytic disease of the newborn. Hemolysis due to minor blood group incompatibility in the fetus or newborn has been determined in isolated case reports. Here, we report a case of a patient who had received red cell transfusion due to severe Rh c and E incompatibility, leading to hemolytic anemia with heart failure. The mother and the baby were grouped B and B, respectively, both being positive for RhD antigen...
June 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Mark Kidd, Irvin Modlin, Kjell Öberg
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) constitute a heterogeneous group of tumours associated with variable clinical presentations, growth rates, and prognoses. To improve the management of GEP-NENs, the WHO developed a classification system that enables tumours to be graded based on markers of cell proliferation in biopsy specimens. Indeed, histopathology has been a mainstay in the diagnosis of GEP-NENs, and the WHO grading system facilitates therapeutic decision-making; however, considerable intratumoural heterogeneity, predominantly comprising regional variations in proliferation rates, complicates the evaluation of tumour biology...
June 7, 2016: Nature Reviews. Clinical Oncology
Florence Petit, Pascal Bailly, Jacques Chiaroni, Stéphane Mazières
BACKGROUND: The treatment of Plasmodium vivax infections requires the use of primaquine, which can lead to severe haemolysis in glucose-6-phosphate dehydrogenase (G6PD)-deficient individuals. However, most of the Latin American countries, which are still endemic for vivax malaria, lack information on the distribution of G6PD deficiency (G6PDd). No survey has been performed so far in French Guiana. Herein, 80 individuals of the French Guianan Noir Marron population were scrutinized for red cell surface antigens of six blood group systems (ABO, Rh, Kell, Kidd, Duffy and MNS) and G6PD genetic polymorphisms...
2016: Malaria Journal
Maria Josie Lategan, William Klare, Sarah Kidd, Grant C Hose, Helena Nevalainen
The recent inclusion of yeasts in environmental monitoring recognizes their ecological significance and sensitivity to toxicants. Here we present a robust and simple two-step toxicity assay and demonstrate the sensitivity of an ubiquitous groundwater yeast, Rhodotorula minuta, to a range of metals and metalloids. The test species was sensitive to copper with a 24h EC50 of 35µg Cu/L, followed in order of decreasing sensitivity by zinc, chromium (VI) and arsenic (EC50 4.40mg As (III)/L). The strain demonstrated an unexpected tolerance to chromium (VI), having an EC50 value (3...
October 2016: Ecotoxicology and Environmental Safety
Swati Kulkarni, K Vasantha, Kanjaksha Ghosh
BACKGROUND: Screening the donor population for clinically important antigens and creating a database of phenotyped donors will eliminate the tedious task of large scale screening for antigen negative units. The aim of the present study is to identify donors lacking common antigens and a combination of common antigens to establish an antigen negative inventory. MATERIALS AND METHODS: Blood samples of 1221 regular blood donors were phenotyped for the clinically important common antigens of the Rh, Duffy, Kell, Kidd and MNS blood group systems using standard tube technique...
August 2016: Transfusion and Apheresis Science
Gülin Güler-Gane, Sara Kidd, Sudharsan Sridharan, Tristan J Vaughan, Trevor C I Wilkinson, Natalie J Tigue
The expression and subsequent purification of mammalian recombinant proteins is of critical importance to many areas of biological science. To maintain the appropriate tertiary structure and post-translational modifications of such proteins, transient mammalian expression systems are often adopted. The successful utilisation of these systems is, however, not always forthcoming and some recombinant proteins prove refractory to expression in mammalian hosts. In this study we focussed on the role of different N-terminal signal peptides and residues immediately downstream, in influencing the level of secreted recombinant protein obtained from suspension HEK293 cells...
2016: PloS One
Riccardo Miotto, Li Li, Brian A Kidd, Joel T Dudley
Secondary use of electronic health records (EHRs) promises to advance clinical research and better inform clinical decision making. Challenges in summarizing and representing patient data prevent widespread practice of predictive modeling using EHRs. Here we present a novel unsupervised deep feature learning method to derive a general-purpose patient representation from EHR data that facilitates clinical predictive modeling. In particular, a three-layer stack of denoising autoencoders was used to capture hierarchical regularities and dependencies in the aggregated EHRs of about 700,000 patients from the Mount Sinai data warehouse...
2016: Scientific Reports
Bryan Reimer, Bruce Mehler, Ian Reagan, David Kidd, Jonathan Dobres
There is limited research on trade-offs in demand between manual and voice interfaces of embedded and portable technologies. Mehler et al. identified differences in driving performance, visual engagement and workload between two contrasting embedded vehicle system designs (Chevrolet MyLink and Volvo Sensus). The current study extends this work by comparing these embedded systems with a smartphone (Samsung Galaxy S4). None of the voice interfaces eliminated visual demand. Relative to placing calls manually, both embedded voice interfaces resulted in less eyes-off-road time than the smartphone...
April 25, 2016: Ergonomics
Rachel A Hodos, Brian A Kidd, Khader Shameer, Ben P Readhead, Joel T Dudley
Data in the biological, chemical, and clinical domains are accumulating at ever-increasing rates and have the potential to accelerate and inform drug development in new ways. Challenges and opportunities now lie in developing analytic tools to transform these often complex and heterogeneous data into testable hypotheses and actionable insights. This is the aim of computational pharmacology, which uses in silico techniques to better understand and predict how drugs affect biological systems, which can in turn improve clinical use, avoid unwanted side effects, and guide selection and development of better treatments...
May 2016: Wiley Interdisciplinary Reviews. Systems Biology and Medicine
M W Roth, B Wandling, T E Kidd, P M Shand, A Stollenwerk
We present the results of extensive Monte Carlo simulations of intercalated manganese-titanium (Mn-Ti) layered TiS2 crystals. The computational model involves mixtures of Mn and Ti in various percentages placed on a triangular lattice with fixed lattice sites and up to five layers. The range of concentrations of intercalated Mn studied was 5%  ⩽  X Mn  ⩽  33% and for Ti, 0%  ⩽  X Ti  ⩽  15%, where X A denotes the percentage of the total number of lattice sites occupied by species A...
May 11, 2016: Journal of Physics. Condensed Matter: An Institute of Physics Journal
Sacha Agrawal, Pat Capponi, Jenna López, Sean Kidd, Charlotte Ringsted, David Wiljer, Sophie Soklaridis
OBJECTIVE: The authors describe a novel course that pairs service users as advisors to senior psychiatry residents with the goals of improving the residents' understanding of recovery, reducing negative stereotypes about people in recovery, and empowering the service users who participated. METHODS: Service users who had experience working as peer support workers and/or system advocates were selected for a broad and deep understanding of recovery and an ability to engage learners in constructive dialogue...
June 2016: Academic Psychiatry
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