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Bioresorbable stent

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https://www.readbyqxmd.com/read/28102777/comparison-of-early-vascular-morphological-changes-between-bioresorbable-poly-l-lactic-acid-scaffolds-and-metallic-stents-in-porcine-iliac-arteries
#1
Yasuhito Sekimoto, Hideaki Obara, Kentaro Matsubara, Naoki Fujimura, Hirohisa Harada, Yuko Kitagawa
Bioresorbable scaffolds have the potential to overcome several problems associated with metallic stents. Bioresorbable poly-L-lactic acid (PLLA) scaffold implantation for the treatment of peripheral artery disease has already been reported in animal models and clinical trials; however, no studies comparing PLLA scaffolds and bare metal stents (BMSs) with regard to early vascular morphological changes, identified using intravascular ultrasound (IVUS) analysis, have been reported. In this study, PLLA scaffolds and BMSs were implanted bilaterally in iliac arteries of five miniature pigs...
January 19, 2017: Organogenesis
https://www.readbyqxmd.com/read/28096169/correction-to-procedural-and-long-term-outcomes-of-bioresorbable-scaffolds-versus-drug-eluting-stents-in-chronic-total-occlusions-the-bonito-registry-bioresorbable-scaffolds-versus-drug-eluting-stents-in-chronic-total-occlusions
#2
https://www.readbyqxmd.com/read/28089777/bioresorbable-vascular-scaffold-to-treat-malignant-in-stent-restenosis-in-a-patient-with-nickel-allergy
#3
Alfonso Jurado-Román, María T López-Lluva, Ignacio Sánchez-Pérez, Jesús Piqueras-Flores, Ramón Maseda, Fernando Lozano-Ruíz-Poveda
Nickel is the most frequent allergen in patients with allergic contact dermatitis and nickel allergy has been associated with recurrent in-stent restenosis. However, it is often misdiagnosed because of a low suspicion threshold. It should be discarded in patients with recurrent in-stent restenosis, especially if their medical history reveals prior contact dermatitis. It is also noteworthy and rarely specified that even newer generation stents that use novel metal alloys also contain low amounts of nickel. To avoid the implantation of new stents containing this metal, when percutaneous coronary intervention is indicated, drug eluting balloons or bioresorbable vascular scaffolds associated with small doses of steroids could provide good alternatives of treatment...
January 2, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28067196/management-of-st-elevation-myocardial-infarction-in-young-patients-by-limiting-implantation-of-durable-intracoronary-devices-and-guided-by-optical-frequency-domain-imaging-proof-of-concept-study
#4
Nicolas Combaret, Géraud Souteyrand, Nicolas Barber-Chamoux, Guilhem Malcles, Aimé Amonchot, Bruno Pereira, Louis Le Bivic, Romain Eschalier, Romain Trésorier, Pascal Motreff
AIMS: To demonstrate the feasibility and safety of ST-elevation myocardial infarction (STEMI) management in young patients by limiting implantation of durable intracoronary devices (using bioresorbable stent or medical treatment alone). METHODS AND RESULTS: Patients <50 years admitted for STEMI with single vessel disease received a two-stage management strategy. During a second coronary angiography performed between day 2 and day 7, optical frequency domain imaging (OFDI) enabled to guide therapeutic management: i) in the case of a stenosis greater that 70% or plaque prolapse, implantation of a BVS; ii) in the other cases, continuation of medical management alone without stenting...
January 10, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28057284/very-late-scaffold-thrombosis-of-bioresorbable-vascular-scaffold-systematic-review-and%C3%A2-a%C3%A2-meta-analysis
#5
Toshiaki Toyota, Takeshi Morimoto, Hiroki Shiomi, Yusuke Yoshikawa, Hidenori Yaku, Yugo Yamashita, Takeshi Kimura
OBJECTIVES: This study sought to compare the 2-year outcomes between bioresorbable vascular scaffold (BVS) and everolimus-eluting metallic drug-eluting stent (EES). BACKGROUND: The occurrence of very late stent/scaffold thrombosis (VLST) of BVS beyond 1 year after implantation is an increasing concern. METHODS: We conducted a meta-analysis of 24 studies (BVS: n = 2,567 and EES: n = 19,806) reporting the 2-year outcomes of BVS and/or EES to compare the risk of BVS versus EES for stent/scaffold thrombosis (ST) and target lesion failure (TLF) in 7 comparative studies (3 randomized and 4 observational), and to estimate the pooled incidence rates of ST and TLF including additional 17 single-arm studies...
January 9, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28045410/clinical-and-angiographic-outcomes-at-more-than-1-year-after-treatment-of-chronic-total-occlusions-with-the-everolimus-eluting-bioresorbable-vascular-scaffold
#6
Aylin Hatice Yamaç, Abdülkadir Yıldız, Meherrem Nasifov, Ahmet Taştan, Nemat Bashirov, Ömer Göktekin
OBJECTIVE: Treatment of chronic total occlusion (CTO) with everolimus-eluting bioresorbable vascular scaffold (BVS) is safe and effective at short-term follow-up (FU). The current study investigated clinical and angiographic outcomes after treatment of CTO with BVS at >1 year. METHODS: Thirty patients who underwent successful recanalization of 35 CTOs were included in this study. Quantitative coronary angiography (QCA) was performed at median FU period of 402 days...
December 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28038806/bioresorbable-coronary-stent-for-the-treatment-of-complex-coronary-lesions-data-from-an-all-comer-registry
#7
Andrea Cuculo, Antonio Ruggiero, Antonio Centola, Giulio Campanale, Tommaso Passero, Antonio Gaglione, Matteo Di Biase, Natale Daniele Brunetti
BACKGROUND: The study aimed to report the results from an all-comers registry of patients undergoing coronary angioplasty and treated with bioresorbable vascular scaffold (BVS). METHODS: Fifty-five consecutive patients with type B/C coronary lesions according to the AHA classification and treated with BVS were enrolled in the study. The clinical and procedural characteristics of enrolled patients were recorded. Fifty-five consecutive subjects with coronary lesions type B/C treated with everolimus eluting stent (EES) were used as control group...
December 19, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28030655/percutaneous-coronary-intervention-with-bioresorbable-scaffolds-in-a-young-child
#8
Tamim M Nazif, Sanjog Kalra, Ziad A Ali, Dimitrios Karmpaliotis, Mariel E Turner, Thomas J Starc, Yang Cao, Charles C Marboe, Michael B Collins, Martin B Leon, Ajay J Kirtane
Importance: Although much less frequent than in adults, coronary artery disease requiring revascularization may develop in children because of homozygous familial hypercholesterolemia or other underlying conditions. Percutaneous coronary intervention (PCI) with a bioresorbable scaffold (BRS) may have advantages over metallic coronary stents in this population. Objective: To present a case of the successful treatment of unstable, multivessel coronary artery disease in a child with PCI with BRS implantation...
December 28, 2016: JAMA Cardiology
https://www.readbyqxmd.com/read/28025048/tropoelastin-inhibits-intimal-hyperplasia-of-mouse-bioresorbable-arterial-vascular-grafts
#9
Tadahisa Sugiura, Riddhima Agarwal, Shuhei Tara, Tai Yi, Yong-Ung Lee, Christopher K Breuer, Anthony S Weiss, Toshiharu Shinoka
: Neointimal hyperplasia, which results from the activation, proliferation and migration of vascular smooth muscle cells (SMCs), is a detrimental condition for vascular stents or vascular grafts that leads to stenosis. Preventing neointimal hyperplasia of vascular grafts is critically important for the success of arterial vascular grafts. We hypothesized that tropoelastin seeding onto the luminal surface of the graft would prevent neointimal hyperplasia through suppressing neointimal smooth muscle cell proliferation...
December 23, 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/28017311/efficacy-and-safety-of-the-absorb-everolimus-eluting-bioresorbable-scaffold%C3%A2-for-treatment-of-patients%C3%A2-with%C3%A2-diabetes-mellitus-results-of-the-absorb-diabetic-substudy
#10
Dean J Kereiakes, Stephen G Ellis, Takeshi Kimura, Alexandre Abizaid, Weiying Zhao, Susan Veldhof, Minh-Thien Vu, Zhen Zhang, Yoshinobu Onuma, Bernard Chevalier, Patrick W Serruys, Gregg W Stone
OBJECTIVES: The study sought to evaluate the efficacy and safety of the Absorb everolimus-eluting bioresorbable vascular scaffold (BVS) (Abbott Vascular, Abbott Park, Illinois) in patients with diabetes mellitus. BACKGROUND: Randomized, controlled trials have demonstrated comparable clinical outcomes following percutaneous coronary intervention with either Absorb BVS or metallic Xience everolimus-eluting stent. However, these trials lack power required to provide reliable treatment effect estimates in this high-risk population...
December 1, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28012050/comparative-assessment-of-plaque-media-change-on-three-modalities-of-ivus-immediately-after-implantation-of-either-everolimus-eluting-bioresorbable-vascular-scaffold-or-everolimus-eluting-metallic-stent-in-absorb-ii-study
#11
Yaping Zeng, Rafael Cavalcante, Erhan Tenekecioglu, Pannipa Suwannasom, Yohei Sotomi, Carlos Collet, Mahammad Abdelghani, Hans Jonker, Franck Digne, Dieter Horstkotte, Manfred Zehender, Ciro Indolfi, Francesco Saia, Rosario Fiorilli, Bernard Chevalier, Leonardo Bolognese, Javier Goicolea, Shaoping Nie, Yoshinobu Onuma, Patrick W Serruys
The purpose of the study to assess the comparability of immediate changes in plaque/media volume (PV) on three modalities of intravascular ultrasound (IVUS) after implantation of either bioresorbable vascular scaffold (BVS) or everolimus-eluting metallic stent (EES) in Absorb II Study. The two devices have different device volume and ultrasound backscattering that may interfere with the "plaque/media" assessed by three modalities on IVUS: grayscale, backscattering of radiofrequency and brightness function. In a multicenter randomized controlled trial, 501 patients with stable or unstable angina underwent documentary IVUS pre- and post- implantation...
December 23, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27998843/coronary-magnetic-resonance-angiographic-images-of-a-lesion-treated-with-a-metal-stent-and-fully-bioresorbable-polymeric-everolimus-eluting-scaffold
#12
Jiro Aoki, Satoru Kishi, Shigeru Saito, Kengo Tanabe
No abstract text is available yet for this article.
December 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27998842/four-year-polymer-biocompatibility-and-vascular-healing-profile-of-a-novel-ultrahigh-molecular-weight-amorphous-plla-bioresorbable-vascular-scaffold-an-oct-study-in-healthy-porcine-coronary-arteries
#13
Torsten P Vahl, Pawel Gasior, Carlos A Gongora, Kamal Ramzipoor, Chang Lee, Yanping Cheng, Jenn McGregor, Masahiko Shibuya, Edward A Estrada, Gerard B Conditt, Greg L Kaluz, Juan F Granada
AIMS: The vascular healing profile of polymers used in bioresorbable vascular scaffolds (BRS) has not been fully characterised in the absence of antiproliferative drugs. In this study, we aimed to compare the polymer biocompatibility profile and vascular healing response of a novel ultrahigh molecular weight amorphous PLLA BRS (FORTITUDE®; Amaranth Medical, Mountain View, CA, USA) against bare metal stent (BMS) controls in porcine coronary arteries. METHODS AND RESULTS: Following device implantation, optical coherence tomography (OCT) evaluation was performed at 0 and 28 days, and at one, two, three and four years...
December 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27993752/clinical-outcomes-of-bioresorbable-versus-durable-polymer-coated-everolimus-eluting-stents-in-real-world-complex-patients
#14
Marco G Mennuni, Giulio G Stefanini, Paolo A Pagnotta, Elton Pllaha, Marco Araco, Omar A Meelu, Federica Turati, Bernhard Reimers, Gennaro Sardella, Patrizia Presbitero
AIMS: To evaluate the safety and efficacy profile of new-generation, Synergy-Everolimus Eluting stents (S-EES) as compared to Xience-EES (X-EES) with durable polymer-coating in "complex patients". METHODS AND RESULTS: We included 2,001 consecutive patients treated with S-EES (n=400) or X- EES (n=1601) at two Italian centers between May 2013 and May 2015. We used propensity-score matching to obtain two cohorts of patients with similar baseline risk profiles. Patients were stratified according to baseline complexity based on the EVOLVE-II trial exclusion criteria...
December 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27970238/tct-844-safety-and-feasibility-of-sirolimus-eluting-bioresorbable-stents-in-porcine-renal-arteries-90-day-angiographic-and-oct-study-in-normal-swine
#15
Ariel Furer, Pawel Gasior, Jenn McGregor, Taylor Palmieri, Gerard Conditt, Juan Granada, Greg Kaluza
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970225/tct-834-bioresorbable-scaffolds-versus-metallic-drug-eluting-stents-comparison-of-predicted-arterial-stress-after-simulated-deployment-in-concentric-and-eccentric-coronary-lesions
#16
Alessandro Schiavone, Chad Abunassar, Liguo Zhao, Syed Hossainy
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970219/tct-828-very-late-vasomotor-responses-and-gene-expression-profiles-of-porcine-coronary-arteries-at-4-years-after-deployment-of-the-everolimus-eluting-bioresorbable-vascular-scaffold-and-the-everolimus-eluting-metallic-xience-v-stent
#17
Bill D Gogas, Sandeep Kumar, James Benham, Deepal Panchal, Yasir Bouchi, Olivia Hung, Rounak Gandhi, Nikolaos Spilias, Esha Singhal, Don P Giddens, Alessandro Veneziani, Richard Rapoza, Spencer King, Hanjoong Jo, Habib Samady
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969936/tct-567-in-vivo-reconstruction-of-bioresorbable-stents-and-its-impact-on-computation-of-shear-stress
#18
Yingguang Li, Niels Holm, Zhenyu Fei, Jouke Dijkstra, Pieter Kitslaar, Emil Holck, Evald Christiansen, Johan Reiber, Shengxian Tu
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969861/tct-49-two-year-clinical-outcome-of-everolimus-eluting-bioresorbable-scaffold-vs-%C3%A2-durable-polymer-everolimus-eluting-metallic-stent-in-patients-with-st-segment-elevation-myocardial-infarction-results-of-the-randomized-absorb-st-segment-elevation-myocardial
#19
Stephan Windecker, Taku Asano, Lorenz Raber, Salvatore Brugaletta, Manel Sabate, Yoshinobu Onuma, Patrick Serruys
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969822/tct-466-bioresorbable-polymer-coated-thin-strut-sirolimus-eluting-stent-versus-durable-polymer-coated-everolimus-eluting-stent-in-daily-clinical-practice-1-year-results-from-interventional-cardiology-network-registry
#20
Pawel Gasior, Marek Gierlotka, Krzysztof Szczurek-Katanski, Marcin Osuch, Lucjan Szela, Michal Hawranek, Andrzej Lekston, Mariusz Gasior, Lech Poloński
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
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