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N Ekin Akalan, Shavkat Kuchimov, Adnan Apti, Yener Temelli, Anand Nene
OBJECTIVE: The goal of the present study was to investigate the relationship between iliopsoas muscle group weakness and related hip joint velocity reduction and stiff-knee gait (SKG) during walking in healthy individuals. METHODS: A load of 5% of each individual's body weight was placed on non-dominant thigh of 15 neurologically intact, able-bodied participants (average age: 22.4 ± 0.81 years). For 33 min (135 s × 13 repetitions × 5 s rest), a passive stretch (PS) was applied with the load in place until hip flexor muscle strength dropped from 5/5 to 3+/5 according to manual muscle test...
November 14, 2016: Acta Orthopaedica et Traumatologica Turcica
Manish Kundanmal Kothari, Kunal Chandrakant Shah, Agnivesh Tikoo, Abhay Madhusudan Nene
STUDY DESIGN: Retrospective study. PURPOSE: To evaluate the factors affecting immediate postoperative mortality in elderly patients with tuberculous spondylodiscitis. OVERVIEW OF LITERATURE: Treatment of spinal tuberculosis in the elderly involves consideration of age and co-morbidities, and often leads to an extended conservative management. Surgical intervention in these patients becomes a complex decision. There are no studies on risk factors of mortality in surgically treated elderly with tuberculous spondylodiscitis...
October 2016: Asian Spine Journal
Eimear M Dunne, Hamish Gordon, Andreas Kürten, João Almeida, Jonathan Duplissy, Christina Williamson, Ismael K Ortega, Kirsty J Pringle, Alexey Adamov, Urs Baltensperger, Peter Barmet, Francois Benduhn, Federico Bianchi, Martin Breitenlechner, Antony Clarke, Joachim Curtius, Josef Dommen, Neil M Donahue, Sebastian Ehrhart, Richard C Flagan, Alessandro Franchin, Roberto Guida, Jani Hakala, Armin Hansel, Martin Heinritzi, Tuija Jokinen, Juha Kangasluoma, Jasper Kirkby, Markku Kulmala, Agnieszka Kupc, Michael J Lawler, Katrianne Lehtipalo, Vladimir Makhmutov, Graham Mann, Serge Mathot, Joonas Merikanto, Pasi Miettinen, Athanasios Nenes, Antti Onnela, Alexandru Rap, Carly L S Reddington, Francesco Riccobono, Nigel A D Richards, Matti P Rissanen, Linda Rondo, Nina Sarnela, Siegfried Schobesberger, Kamalika Sengupta, Mario Simon, Mikko Sipilä, James N Smith, Yuri Stozkhov, Antonio Tomé, Jasmin Tröstl, Paul E Wagner, Daniela Wimmer, Paul M Winkler, Douglas R Worsnop, Kenneth S Carslaw
Fundamental questions remain about the origin of newly formed atmospheric aerosol particles because data from laboratory measurements have been insufficient to build global models. In contrast, gas-phase chemistry models have been based on laboratory kinetics measurements for decades. Here we build a global model of aerosol formation using extensive laboratory-measured nucleation rates involving sulfuric acid, ammonia, ions and organic compounds. The simulations and a comparison with atmospheric observations show that nearly all nucleation throughout the present-day atmosphere involves ammonia or biogenic organic compounds in addition to sulfuric acid...
October 27, 2016: Science
Isabel Benavente-Fernandez, Manuel Lubián-Gutierrez, Gema Jimenez-Gomez, Alfonso M Lechuga-Sancho, Simon P Lubián-López
AIM: Posthaemorrhagic ventricular dilatation (PHVD) is monitored by conventional two-dimensional ultrasound (2DUS). The aims of this study were to determine the volume of the lateral ventricles using three-dimensional ultrasound (3DUS) in preterm infants with PHVD and to evaluate the relationship between volume and linear measurements. METHODS: Serial 2DUSs and 3DUSs were performed on preterm infants with PHVD admitted to the neonatal intensive care unit at Puerta del Mar Hospital, Cádiz, Spain, from January 2013 to December 2014...
October 26, 2016: Acta Paediatrica
Namrata Kewalramani, Amita Nene
Tracheal diverticulum is a rare entity with only 79 symptomatic cases reported till date. We herein describe the case of a 38 year old male who presented with recurrent dry cough and hemoptysis and was diagnosed to have tracheal diverticulum on High Resolution Computed Tomography (HRCT) of chest. This was further confirmed on fibre optic bronchoscopy.
August 2016: Journal of the Association of Physicians of India
Vishvanath Nene, W Ivan Morrison
Despite having different cell tropism, the pathogenesis and immunobiology of the diseases caused by Theileria parva and T. annulata are remarkably similar. Live vaccines have been available for both parasites for over 40 years, but although they provide strong protection, practical disadvantages have limited their widespread application. Efforts to develop alternative vaccines using defined parasite antigens have focused on the sporozoite and intracellular schizont stages of the parasites. Experimental vaccination studies using viral vectors expressing T...
September 20, 2016: Parasite Immunology
A Papayannis, A Argyrouli, A Bougiatioti, E Remoundaki, S Vratolis, A Nenes, S Solomos, M Komppula, E Giannakaki, J Kalogiros, R Banks, K Eleftheriadis, E Mantas, E Diapouli, C G Tzanis, S Kazadzis, I Binietoglou, L Labzovskii, J Vande Hey, C S Zerefos
The international experimental campaign Hygroscopic Aerosols to Cloud Droplets (HygrA-CD), organized in the Greater Athens Area (GAA), Greece from 15 May to 22 June 2014, aimed to study the physico-chemical properties of aerosols and their impact on the formation of clouds in the convective Planetary Boundary Layer (PBL). We found that under continental (W-NW-N) and Etesian (NE) synoptic wind flow and with a deep moist PBL (~2-2.5km height), mixed hygroscopic (anthropogenic, biomass burning and marine) particles arrive over the GAA, and contribute to the formation of convective non-precipitating PBL clouds (of ~16-20μm mean diameter) with vertical extent up to 500m...
September 14, 2016: Science of the Total Environment
Xiaojuan Xia, Anne-Christine Ruwald, Martin H Ruwald, Nene Ugoeke, Barbara Szepietowska, Valentina Kutyifa, Mehmet K Aktas, Poul Erik B Thomsen, Wojciech Zareba, Arthur J Moss, Jean-Philippe Couderc
AIMS: Strict left bundle branch block (LBBB) criteria were recently proposed to identify LBBB patients to benefit most from cardiac resynchronization therapy (CRT). The aim of our study was to automate identification of strict LBBB in order to facilitate its broader application. METHODS: We developed a series of algorithms to automatically detect and measure parameters required for strict LBBB criteria and proposed a definition of QRS notch detection. The algorithms were developed using training (n = 20) and validation (n = 592) sets consisting of signal-averaged 12-lead ECGs (1,000 Hz sampling) recorded from 612 LBBB patients from Multicenter Automatic Defibrillator Implantation Trial-CRT...
August 30, 2016: Annals of Noninvasive Electrocardiology
Sanganagouda S Patil, Abhay M Nene
BACKGROUND: High grade metastatic spinal tumors are most common and are invasive. These patients can succumb to disease progression if not treated timely. Although considered as invasive and morbid, total enbloc spondylectomy (TES) in selected cases has better survival rates. The authors describe the results of TES for high grade metastatic spinal tumors. MATERIALS AND METHODS: Five patients (four females and one male) underwent TES for solitary metastatic vertebral lesion between November 2012 and January 2014...
July 2016: Indian Journal of Orthopaedics
Julia Drylewicz, Ingrid M M Schellens, Rogier Gaiser, Nening M Nanlohy, Esther D Quakkelaar, Henny Otten, Suzanne van Dorp, Ronald Jacobi, Leonie Ran, Sanne Spijkers, Dan Koning, Rob Schuurman, Ellen Meijer, Floortje L Pietersma, Jurgen Kuball, Debbie van Baarle
BACKGROUND: Epstein-Barr virus and Cytomegalovirus reactivations frequently occur after allogeneic stem cell transplantation (SCT). METHODS: Here we investigated the role of immune cell reconstitution in the onset and subsequent severity of EBV- and CMV-reactivation. To this end, 116 patients were prospectively sampled for absolute T cell (CD4 and CD8), B-cell (CD19) and NK-cell (CD16 and CD56) numbers weekly post-SCT during the first 3 months and thereafter monthly until 6 months post-SCT...
2016: Journal of Translational Medicine
Kimberley D Curtin, Christina C Loitz, Nancy Spencer-Cavaliere, Ernest Nene Khalema
Immigrants to Canada are less likely to be physically active compared with non-immigrants, and the interrelations between personal and environmental factors that influence physical activity for immigrants are largely unexplored. The goal of this qualitative descriptive study was to understand how the experience of being new to Canada impacts opportunities and participation in physical activity. Two focus group interviews with immigrants to Canada were conducted. The first group (n=7) included multicultural health brokers...
July 12, 2016: Global Health Promotion
Saul Lozano-Fuentes, Rebekah C Kading, Daniel A Hartman, Edward Okoth, Naftaly Githaka, Vishvanath Nene, Richard M Poché
BACKGROUND: Although vector control strategies, such as insecticide-treated bed nets (ITNs) and indoor residual spraying (IRS) have been effective in Kenya the transmission of malaria continues to afflict western Kenya. This residual transmission is driven in part by Anopheles arabiensis, known for its opportunistic blood feeding behaviour and propensity to feed outdoors. The objective of this research was to evaluate the efficacy of the drug eprinomectin at reducing malaria vector density when applied to cattle (Bos indicus), the primary source of blood for An...
2016: Malaria Journal
Glen P Davis, Andrew Tomita, Joy Noel Baumgartner, Sisanda Mtshemla, Siphumelele Nene, Howard King, Ezra Susser, Jonathan K Burns
BACKGROUND: Substance use and psychiatric disorders cause significant burden of disease in low- and middle-income countries. Co-morbid psychopathology and longer duration of untreated psychosis (DUP) can negatively affect treatment outcomes. OBJECTIVES: The study assessed substance use amongst adults with severe mental illness receiving services at a regional psychiatric hospital in KwaZulu-Natal (South Africa). We describe the prevalence and correlates of lifetime substance use and examine the association between substance use and DUP...
2016: South African Journal of Psychiatry: SAJP: the Journal of the Society of Psychiatrists of South Africa
Kalliopi Violaki, Ting Fang, Nikos Mihalopoulos, Rodney Weber, Athanasios Nenes
We present a novel automated system for real-time measurements of water-soluble reactive phosphate (SRP) ions in atmospheric particles. Detection of SRP is based on molybdenum blue chemistry with Sn(II) chloride dihydrate reduction. The instrumentation consists of one particle-into-liquid sampler (PILS) coupled with a 250 cm path length liquid waveguide capillary cell (LWCC) and miniature fiber optic spectrometer, with detection wavelength set at 690 nm. The detection limit was 0.4 nM P, equivalent to 0.03 nmol P m(-3) in atmospheric particles...
July 19, 2016: Analytical Chemistry
Amelia F Longo, Yan Feng, Barry Lai, William M Landing, Rachel U Shelley, Athanasios Nenes, Nikolaos Mihalopoulos, Kalliopi Violaki, Ellery D Ingall
Aerosol iron was examined in Saharan dust plumes using a combination of iron near-edge X-ray absorption spectroscopy and wet-chemical techniques. Aerosol samples were collected at three sites located in the Mediterranean, the Atlantic, and Bermuda to characterize iron at different atmospheric transport lengths and time scales. Iron(III) oxides were a component of aerosols at all sampling sites and dominated the aerosol iron in Mediterranean samples. In Atlantic samples, iron(II and III) sulfate, iron(III) phosphate, and iron(II) silicates were also contributors to aerosol composition...
July 5, 2016: Environmental Science & Technology
Anthony Scott Burns, Indira Lanig, Klemen Grabljevec, Peter Wayne New, Djamel Bensmail, Per Ertzgaard, Anand Vishwanath Nene
Optimizing the treatment of disabling spasticity in persons with spinal cord damage is hampered by a lack of consensus regarding the use of acceptable definitions of spasticity and disabling spasticity, and the relative absence of decision tools such as clinical guidelines and concise algorithms to support decision-making within the broader clinical community. Many people with spinal cord damage are managed outside specialist centers, and variations in practice result in unequal access to best practice despite equal need...
December 2016: Archives of Physical Medicine and Rehabilitation
John H Seinfeld, Christopher Bretherton, Kenneth S Carslaw, Hugh Coe, Paul J DeMott, Edward J Dunlea, Graham Feingold, Steven Ghan, Alex B Guenther, Ralph Kahn, Ian Kraucunas, Sonia M Kreidenweis, Mario J Molina, Athanasios Nenes, Joyce E Penner, Kimberly A Prather, V Ramanathan, Venkatachalam Ramaswamy, Philip J Rasch, A R Ravishankara, Daniel Rosenfeld, Graeme Stephens, Robert Wood
The effect of an increase in atmospheric aerosol concentrations on the distribution and radiative properties of Earth's clouds is the most uncertain component of the overall global radiative forcing from preindustrial time. General circulation models (GCMs) are the tool for predicting future climate, but the treatment of aerosols, clouds, and aerosol-cloud radiative effects carries large uncertainties that directly affect GCM predictions, such as climate sensitivity. Predictions are hampered by the large range of scales of interaction between various components that need to be captured...
May 24, 2016: Proceedings of the National Academy of Sciences of the United States of America
Sylvia C Sullivan, Dongmin Lee, Lazaros Oreopoulos, Athanasios Nenes
Understanding how dynamical and aerosol inputs affect the temporal variability of hydrometeor formation in climate models will help to explain sources of model diversity in cloud forcing, to provide robust comparisons with data, and, ultimately, to reduce the uncertainty in estimates of the aerosol indirect effect. This variability attribution can be done at various spatial and temporal resolutions with metrics derived from online adjoint sensitivities of droplet and crystal number to relevant inputs. Such metrics are defined and calculated from simulations using the NASA Goddard Earth Observing System Model, Version 5 (GEOS-5) and the National Center for Atmospheric Research Community Atmosphere Model Version 5...
May 24, 2016: Proceedings of the National Academy of Sciences of the United States of America
Ari Laaksonen, Jussi Malila, Athanasios Nenes, Hui-Ming Hung, Jen-Ping Chen
Surface porosity affects the ability of a substance to adsorb gases. The surface fractal dimension D is a measure that indicates the amount that a surface fills a space, and can thereby be used to characterize the surface porosity. Here we propose a new method for determining D, based on measuring both the water vapour adsorption isotherm of a given substance, and its ability to act as a cloud condensation nucleus when introduced to humidified air in aerosol form. We show that our method agrees well with previous methods based on measurement of nitrogen adsorption...
2016: Scientific Reports
Adnan Apti, N Ekin Akalan, Shavkat Kuchimov, Arzu Razak Özdinçler, Yener Temelli, Anand Nene
AIM: The iterative simulation studies proclaim that plantar flexor (PF) muscle weakness is one of the contributors of stiff knee gait (SKG), although, whether isolated PF weakness generates SKG has not been validated in able-bodied people or individuals with neuromuscular disorders. The aim of the study was to investigate the effects of isolated PF muscle weakness on knee flexion velocity and SKG in healthy individuals. METHOD: Twenty able-bodied young adults (23±3 years) participated in this study...
May 2016: Gait & Posture
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