keyword
https://read.qxmd.com/read/38700413/nccp-ics-joint-consensus-based-clinical-practice-guidelines-on-medical-thoracoscopy
#1
JOURNAL ARTICLE
Rakesh K Chawla, Mahendra Kumar, Arun Madan, Raja Dhar, Richa Gupta, Dipti Gothi, Unnati Desai, Manoj Goel, Rajesh Swarankar, Amita Nene, Radha Munje, Dhruv Chaudhary, Randeep Guleria, Vijay Hadda, Vivek Nangia, Girish Sindhwani, Rajesh Chawla, Naveen Dutt, Yuvarajan, Sonia Dalal, Shailendra Nath Gaur, Subodh Katiyar, Jai Kumar Samaria, K B Gupta, Parvaiz A Koul, Suryakant, D J Christopher, Dhrubajyoti Roy, Basant Hazarika, Shanti Kumar Luhadia, Anand Jaiswal, Karan Madan, Prem Parkash Gupta, B N B M Prashad, Nasser Yusuf, Prince James, Amit Dhamija, Veerotam Tomar, Ujjwal Parakh, Ajmal Khan, Rakesh Garg, Sheetu Singh, Vinod Joshi, Nikhil Sarangdhar, Sushmita Roy Chaudhary, Sandeep Nayar, Anand Patel, Mansi Gupta, Rama Kant Dixit, Sushil Jain, Pratibha Gogia, Manish Agarwal, Sandeep Katiyar, Aditya Chawla, Hari Kishan Gonuguntala, Ravi Dosi, Vijya Chinnamchetty, Apar Jindal, Shubham Sharma, Vaibhav Chachra, Utsav Samaria, Avinash Nair, Shruti Mohan, Gargi Maitra, Ashish Sinha, Rishabh Kochar, Ajit Yadav, Gaurav Choudhary, M Arunachalam, Amith Rangarajan, Ganesh Sanjan
Medical Thoracoscopy (MT) is commonly performed by respiratory physicians for diagnostic as well as therapeutic purposes. The aim of the study was to provide evidence-based information regarding all aspects of MT, both as a diagnostic tool and therapeutic aid for pulmonologists across India. The consensus-based guidelines were formulated based on a multistep process using a set of 31 questions. A systematic search of published randomized controlled clinical trials, open labelled studies, case reports and guidelines from electronic databases, like PubMed, EmBase and Cochrane, was performed...
March 1, 2024: Lung India: Official Organ of Indian Chest Society
https://read.qxmd.com/read/38685138/anticancer-photodynamic-activities-of-triphenylphosphine-labelled-phthalocyanines-and-their-bovine-serum-albumin-gold-nanoparticles-complexes-on-melanoma-a375-cell-lines-in-vitro
#2
JOURNAL ARTICLE
Lindokuhle Cindy Nene, Nkune Williams Nkune, Heidi Abrahamse
This work reports on the synthesis of triphenylphosphine-labelled cationic phthalocyanines (Pc) complexed with bovine serum albumin (BSA) and gold nanoparticles (Au NPs). This nano-complex (Pc-BSA-Au) is studied for its photodynamic therapy (PDT) activity compared to the non-complexed Pc counterpart. The photochemical properties and in vitro PDT efficacies of the Pc and the nano-complex were determined and are compared herein. The singlet oxygen (1 O2 ) yields of the Pcs were determined and are reported in DMF...
April 23, 2024: Journal of Inorganic Biochemistry
https://read.qxmd.com/read/38628231/experiences-of-families-living-with-nyaope-users-in-tshwane-gauteng-province
#3
JOURNAL ARTICLE
Dorcas Nene, Florah Mkhonto, Kebogile E Mokwena
BACKGROUND: Nyaope is one of the commonly used drugs in many low socio-economic communities in South Africa. Because of its highly addictive properties, the vast majority of users are not able to quit, which results in long-term difficulties for their families. AIM: The aim of this study was to explore and describe the experiences of families living with nyaope users in a township in Tshwane Metropolitan Municipality. SETTING: Data were collected at the Social Development Centre, which serves a variety of social needs of families, including the various needs of families whose problems emanate from nyaope use...
2024: Health SA, SA Gesondheid
https://read.qxmd.com/read/38623471/methicillin-resistant-staphylococcus-aureus-carriage-among-neonate-mothers-healthcare-workers-and-environmental-samples-in-neonatal-intensive-care-units-a-systematic-review
#4
JOURNAL ARTICLE
Nene Kaah Keneh, Sebastien Kenmoe, Arnol Bowo-Ngandji, Jane-Francis Tatah Kihla Akoachere, Hortense Gonsu Kamga, Roland Ndip Ndip, Jean Thierry Ebogo-Belobo, Cyprien Kengne-Ndé, Donatien Serge Mbaga, Nicholas Tendongfor, Jean Paul Assam Assam, Lucy Mande Ndip, Seraphine Nkie Esemu
BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) is a significant cause of morbidity and mortality among neonates admitted to neonatal intensive care units (NICUs). The MRSA colonization of neonates, attributed to various sources, including mothers, healthcare workers, and environmental surfaces, can lead to severe infection, prolonged hospital stays, and even death, imposing substantial economic burdens. Given the pressing need to mitigate MRSA spread in these vulnerable environments, further examination of the subject is warranted...
2024: BioMed Research International
https://read.qxmd.com/read/38621222/sudden-reduction-in-caffeine-intake-increases-serum-lithium-concentration-to-supratherapeutic-level-a-case-report
#5
JOURNAL ARTICLE
Jeffrey J Song, Jorgen C Eyabi, Poonam D Awatramani, Brian G Mitchell, Sudhanshu Y Nene
No abstract text is available yet for this article.
April 11, 2024: Primary Care Companion to CNS Disorders
https://read.qxmd.com/read/38594181/factors-influencing-pregnancy-care-and-institutional-delivery-in-rural-mali-a-secondary-baseline-analysis-of-a-cluster-randomised-trial
#6
JOURNAL ARTICLE
Rakesh Ghosh, Aminata Nene Konipo, Emily Treleaven, Sasha Rozenshteyn, Jessica Beckerman, Caroline Whidden, Ari Johnson, Kassoum Kayentao, Jenny Liu
OBJECTIVE: The vast majority of the 300 000 pregnancy-related deaths every year occur in South Asia and sub-Saharan Africa. Increased access to quality antepartum and intrapartum care can reduce pregnancy-related morbidity and mortality worldwide. We used a population-based cross-sectional cohort design to: (1) examine the sociodemographic risk factors and structural barriers associated with pregnancy care-seeking and institutional delivery, and (2) investigate the influence of residential distance to the nearest primary health facility in a rural population in Mali...
April 9, 2024: BMJ Open
https://read.qxmd.com/read/38587880/association-of-arterial-stiffness-with-mid-to-long-term-home-blood-pressure-variability-in-the-electronic-framingham-heart-study-cohort-study
#7
JOURNAL ARTICLE
Xuzhi Wang, Yuankai Zhang, Chathurangi H Pathiravasan, Nene C Ukonu, Jian Rong, Emelia J Benjamin, David D McManus, Martin G Larson, Ramachandran S Vasan, Naomi M Hamburg, Joanne M Murabito, Chunyu Liu, Gary F Mitchell
BACKGROUND: Short-term blood pressure variability (BPV) is associated with arterial stiffness in patients with hypertension. Few studies have examined associations between arterial stiffness and digital home BPV over a mid- to long-term time span, irrespective of underlying hypertension. OBJECTIVE: This study aims to investigate if arterial stiffness traits were associated with subsequent mid- to long-term home BPV in the electronic Framingham Heart Study (eFHS)...
April 8, 2024: JMIR Cardio
https://read.qxmd.com/read/38572602/progressive-thrombosis-of-a-dolicho-basilar-artery-and-fusiform-aneurysm-resulting-in-diffuse-ischemic-and-hemorrhagic-complications
#8
JOURNAL ARTICLE
Vincent Brissette, Marina Saad, Devavrat Nene, Christine Van Winssen, Ange Boubacar Diouf, Marlise P Dos Santos, Robert Fahed, Célina Ducroux
No abstract text is available yet for this article.
April 4, 2024: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/38571648/distribution-characterization-and-chemical-management-of-noxious-shrub-weed-dichapetalum-stuhlmannii-engl-in-cashew-in-southeastern-tanzania
#9
JOURNAL ARTICLE
William V Mbasa, Fortunus A Kapinga, Wilson A Nene, Andrew K Kabanza, Abdallah R Makale, Kasiga N Ngiha, Ramadhani A Bashiru
Weeds are among the limiting factors that influence low production of economically important crops including cashew ( Anacardium occidental L.). Shrub weeds attribute to inter-competition for resources, hinder harvesting and ultimately reduce cashew yields in Tanzania. The current study determined the distribution, characteristics and chemical control option of Dichapetalum Engl in Lindi and Mtwara regions, Southeastern Tanzania. The distribution study involved a survey for weed presence along the areas of Lindi and Mtwara regions...
April 15, 2024: Heliyon
https://read.qxmd.com/read/38509343/high-mobility-group-box-1-cytokine-targeted-topical-delivery-of-resveratrol-embedded-nanoemulgel-for-the-management-of-atopic-dermatitis
#10
JOURNAL ARTICLE
Shweta Nene, Geetanjali Devabattula, Ganesh Vambhurkar, Kamatham Pushpa Tryphena, Pankaj Kumar Singh, Dharmendra Kumar Khatri, Chandraiah Godugu, Saurabh Srivastava
Resveratrol is a polyphenolic compound showing anti-inflammatory activity by inhibition of high mobility group box 1 cytokine responsible for the activation of nuclear factor-κB pathway in atopic dermatitis. To evaluate the efficacy of resveratrol through topical route we have developed resveratrol-loaded nanoemulgel for the effective management of atopic dermatitis in mice model. The resveratrol-loaded nanoemulsion (0.5%, 0.75% and 1% w/w) was optimized by spontaneous nano-emulsification. The optimized resveratrol-loaded nanoemulsions showed average globule size in the 180-230 nm range and found to be monodispersed...
March 20, 2024: Drug Delivery and Translational Research
https://read.qxmd.com/read/38502572/effects-of-trastuzumab-emtansine-on-canine-urothelial-carcinoma-cells-in-vitro-and-in-vivo
#11
JOURNAL ARTICLE
Kosei Sakai, Daiki Kato, Junka Yoshinaka, Yosuke Takahashi, Namiko Ikeda, Susumu Aoki, Takaaki Iguchi, Shingo Ishikawa, Norio Yamagishi, Shunsuke Shimamura, Takayuki Nakagawa
Urothelial carcinoma (UC) is the most common malignancy of the urinary tract in dogs and has aggressive behaviour. Although human epidermal growth factor receptor 2 (HER2) is a known therapeutic target with evidence in canine UC, the efficacy of anti-HER2 antibody drugs remains unknown. This study aimed to investigate the effects of anti-HER2 antibody drugs including trastuzumab and trastuzumab emtansine (T-DM1) on canine UC cell lines in vitro and in vivo. Four canine UC cell lines (Nene, TCCUB, Love, and Sora) were used...
March 19, 2024: Veterinary and Comparative Oncology
https://read.qxmd.com/read/38486981/design-consideration-of-phthalocyanines-as-sensitizers-for-enhanced-sono-photodynamic-combinatorial-therapy-of-cancer
#12
REVIEW
Lindokuhle Cindy Nene, Heidi Abrahamse
Cancer remains one of the diseases with the highest incidence and mortality globally. Conventional treatment modalities have demonstrated threatening drawbacks including invasiveness, non-controllability, and development of resistance for some, including chemotherapy, radiation, and surgery. Sono-photodynamic combinatorial therapy (SPDT) has been developed as an alternative treatment modality which offers a non-invasive and controllable therapeutic approach. SPDT combines the mechanism of action of sonodynamic therapy (SDT), which uses ultrasound, and photodynamic therapy (PDT), which uses light, to activate a sensitizer and initiate cancer eradication...
March 2024: Acta Pharmaceutica Sinica. B
https://read.qxmd.com/read/38482269/overview-of-the-alaskan-layered-pollution-and-chemical-analysis-alpaca-field-experiment
#13
JOURNAL ARTICLE
William R Simpson, Jingqiu Mao, Gilberto J Fochesatto, Kathy S Law, Peter F DeCarlo, Julia Schmale, Kerri A Pratt, Steve R Arnold, Jochen Stutz, Jack E Dibb, Jessie M Creamean, Rodney J Weber, Brent J Williams, Becky Alexander, Lu Hu, Robert J Yokelson, Manabu Shiraiwa, Stefano Decesari, Cort Anastasio, Barbara D'Anna, Robert C Gilliam, Athanasios Nenes, Jason M St Clair, Barbara Trost, James H Flynn, Joel Savarino, Laura D Conner, Nathan Kettle, Krista M Heeringa, Sarah Albertin, Andrea Baccarini, Brice Barret, Michael A Battaglia, Slimane Bekki, T J Brado, Natalie Brett, David Brus, James R Campbell, Meeta Cesler-Maloney, Sol Cooperdock, Karolina Cysneiros de Carvalho, Hervé Delbarre, Paul J DeMott, Conor J S Dennehy, Elsa Dieudonné, Kayane K Dingilian, Antonio Donateo, Konstantinos M Doulgeris, Kasey C Edwards, Kathleen Fahey, Ting Fang, Fangzhou Guo, Laura M D Heinlein, Andrew L Holen, Deanna Huff, Amna Ijaz, Sarah Johnson, Sukriti Kapur, Damien T Ketcherside, Ezra Levin, Emily Lill, Allison R Moon, Tatsuo Onishi, Gianluca Pappaccogli, Russell Perkins, Roman Pohorsky, Jean-Christophe Raut, Francois Ravetta, Tjarda Roberts, Ellis S Robinson, Federico Scoto, Vanessa Selimovic, Michael O Sunday, Brice Temime-Roussel, Xinxiu Tian, Judy Wu, Yuhan Yang
The Alaskan Layered Pollution And Chemical Analysis (ALPACA) field experiment was a collaborative study designed to improve understanding of pollution sources and chemical processes during winter (cold climate and low-photochemical activity), to investigate indoor pollution, and to study dispersion of pollution as affected by frequent temperature inversions. A number of the research goals were motivated by questions raised by residents of Fairbanks, Alaska, where the study was held. This paper describes the measurement strategies and the conditions encountered during the January and February 2022 field experiment, and reports early examples of how the measurements addressed research goals, particularly those of interest to the residents...
March 8, 2024: ACS EST Air
https://read.qxmd.com/read/38482268/indoor-outdoor-oxidative-potential-of-pm-2-5-in-wintertime-fairbanks-alaska-impact-of-air-infiltration-and-indoor-activities
#14
JOURNAL ARTICLE
Yuhan Yang, Michael A Battaglia, Ellis S Robinson, Peter F DeCarlo, Kasey C Edwards, Ting Fang, Sukriti Kapur, Manabu Shiraiwa, Meeta Cesler-Maloney, William R Simpson, James R Campbell, Athanasios Nenes, Jingqiu Mao, Rodney J Weber
The indoor air quality of a residential home during winter in Fairbanks, Alaska, was investigated and contrasted with outdoor levels. Twenty-four-hour average indoor and outdoor filter samples were collected from January 17 to February 25, 2022, in a residential area with high outdoor PM2.5 concentrations. The oxidative potential of PM2.5 was determined using the dithiothreitol-depletion assay (OPDTT ). For the unoccupied house, the background indoor-to-outdoor (I/O) ratio of mass-normalized OP (OPm DTT ), a measure of the intrinsic health-relevant properties of the aerosol, was less than 1 (0...
March 8, 2024: ACS EST Air
https://read.qxmd.com/read/38482267/assessing-the-oxidative-potential-of-outdoor-pm-2-5-in-wintertime-fairbanks-alaska
#15
JOURNAL ARTICLE
Yuhan Yang, Michael A Battaglia, Magesh Kumaran Mohan, Ellis S Robinson, Peter F DeCarlo, Kasey C Edwards, Ting Fang, Sukriti Kapur, Manabu Shiraiwa, Meeta Cesler-Maloney, William R Simpson, James R Campbell, Athanasios Nenes, Jingqiu Mao, Rodney J Weber
The oxidative potential (OP) of outdoor PM2.5 in wintertime Fairbanks, Alaska, is investigated and compared to those in wintertime Atlanta and Los Angeles. Approximately 40 filter samples collected in January-February 2022 at a Fairbanks residential site were analyzed for OP utilizing dithiothreitol-depletion (OPDTT ) and hydroxyl-generation (OPOH ) assays. The study-average PM2.5 mass concentration was 12.8 μg/m3 , with a 1 h average maximum of 89.0 μg/m3 . Regression analysis, correlations with source tracers, and contrast between cold and warmer events indicated that OPDTT was mainly sensitive to copper, elemental carbon, and organic aerosol from residential wood burning, and OPOH to iron and organic aerosol from vehicles...
March 8, 2024: ACS EST Air
https://read.qxmd.com/read/38433166/sarcopenia-and-its-effects-on-outcome-of-lumbar-spine-surgeries
#16
JOURNAL ARTICLE
Manojkumar B Gaddikeri, Abhay Nene, Priyank Patel, Harshal Bamb, Shubhanshu Bhaladhare
PURPOSE: Sarcopenia, defined as progressive impairment of muscle function secondary to loss of skeletal muscle mass, has prevalence of 24-56% in patients > 60 years. Forty-four per cent of elderly patients undergoing orthopaedic surgery are found to be sarcopenic. It is a known risk factor for fall, fractures, disability, increased post-operative morbidity and mortality. If diagnosed pre-operatively, it can help prepare the patient and surgical team to foresee complications and thereby reduce morbidity and mortality...
March 3, 2024: European Spine Journal
https://read.qxmd.com/read/38401819/phthalocyanine-based-probes-in-alleviating-or-evading-tumour-hypoxia-for-enhanced-photo-and-sono-mediated-therapeutic-efficacies
#17
REVIEW
Lindokuhle Cindy Nene, Heidi Abrahamse
This review discusses the possible methods for improving therapeutic efficacies of phthalocyanine (Pcs) -based therapeutic probes in photo- and sono-dynamic therapies under hypoxic conditions. Herein, the structural design strategies including varying the central metal, position substituents and the effects of adjuvant used in supplementing the therapeutics activities of Pcs or formation of NPs are discussed for cancer therapies in hypoxic conditions. Different mechanisms induced for cell death influenced by the compositions of the Pcs-probes are discussed...
February 22, 2024: Photodiagnosis and Photodynamic Therapy
https://read.qxmd.com/read/38374958/metagenomic-characterization-of-poultry-cloacal-and-oropharyngeal-swabs-in-kenya-reveals-bacterial-pathogens-and-their-antimicrobial-resistance-genes
#18
JOURNAL ARTICLE
Philip M Panyako, Sheila C Ommeh, Stephen N Kuria, Jacqueline K Lichoti, Johns Musina, Venugopal Nair, Vish Nene, Muhammad Munir, Samuel O Oyola
Poultry enteric bacterial diseases are of significant economic importance because they are responsible for production losses due to weight loss, increased morbidity and mortality, and increased cost of production arising from poor feed conversion and treatment. This cross-sectional purposive study characterized enteric bacterial pathogens in poultry from selected agroclimatic regions in Kenya and investigated their antimicrobial resistance gene profiles. Cloacal ( n  = 563) and oropharyngeal ( n  = 394) swabs were collected and pooled into 16 and 14 samples, respectively, to characterize bacterial pathogens and their antimicrobial resistance gene profiles...
2024: International Journal of Microbiology
https://read.qxmd.com/read/38371604/the-molecular-scale-mechanism-of-deposition-ice-nucleation-on-silver-iodide
#19
JOURNAL ARTICLE
Golnaz Roudsari, Mária Lbadaoui-Darvas, André Welti, Athanasios Nenes, Ari Laaksonen
Heterogeneous ice nucleation is a ubiquitous process in the natural and built environment. Deposition ice nucleation, i.e. heterogeneous ice nucleation that - according to the traditional view - occurs in a subsaturated water vapor environment and in the absence of supercooled water on the solid, ice-forming surface, is among the most important ice formation processes in high-altitude cirrus and mixed-phase clouds. Despite its importance, very little is known about the mechanism of deposition ice nucleation at the microscopic level...
February 15, 2024: Environ Sci Atmos
https://read.qxmd.com/read/38369728/post-stroke-depression-and-suicidal-ideations-relationship-with-gender-and-marital-status-a-cross-sectional-study
#20
JOURNAL ARTICLE
Mgbeojedo Ukamaka Gloria, Osiri Emmanuel Jonah, Akosile Christopher Olusanjo, Okoye Emmanuel Chiebuka, John Jeneviv Nene, Akobundu Uzoamaka Nwakego, Anyaene Chiamaka Chinyere
OBJECTIVES: To determine the prevalence and contributing factors of depression and suicidal ideations among stroke survivors in Nigeria. METHODS: This was a cross-sectional study comprising 75 consenting stroke survivors who were purposively recruited from 2 tertiary hospitals. Suicidal ideations and depression were measured using standard questionnaires. Obtained data was analyzed with appropriate statistical tools. RESULTS: 9.3% of the participants had depression while 4% reported suicidal ideations...
2024: Journal of Primary Care & Community Health
keyword
keyword
11661
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.