keyword
https://read.qxmd.com/read/33546734/management-of-renin-angiotensin-aldosterone-system-blockade-in-patients-admitted-to-hospital-with-confirmed-coronavirus-disease-covid-19-infection-the-mcgill-raas-covid-19-a-structured-summary-of-a-study-protocol-for-a-randomized-controlled-trial
#21
JOURNAL ARTICLE
Mona Aflaki, Alexandria Flannery, João Pedro Ferreira, Matthew Pellan Cheng, Nadine Kronfli, Ariane Marelli, Faiez Zannad, James Brophy, Jon Afillalo, Thao Huynh, Nadia Giannetti, Amal Bessissow, Justin A Ezekowitz, Renato D Lopes, Andrew P Ambrosy, Morgan Craig, Abhinav Sharma
OBJECTIVES: The aim of the RAAS-COVID-19 randomized control trial is to evaluate whether an upfront strategy of temporary discontinuation of renin angiotensin aldosterone system (RAAS) inhibition versus continuation of RAAS inhibition among patients admitted with established COVID-19 infection has an impact on short term clinical and biomarker outcomes. We hypothesize that continuation of RAAS inhibition will be superior to temporary discontinuation with regards to the primary endpoint of a global rank sum score...
February 5, 2021: Trials
https://read.qxmd.com/read/33482377/impact-of-covid-19-on-the-society-for-vascular-surgery-vascular-quality-initiative-venous-procedure-registries-varicose-vein-and-inferior-vena-cava-filter
#22
COMPARATIVE STUDY
Ashorne K Mahenthiran, Jay P Natarajan, Daniel J Bertges, Kristopher M Huffman, Jens Eldrup-Jorgensen, Gary W Lemmon
In response to the pandemic, an abrupt pivot of Vascular Quality Initiative physician members away from standard clinical practice to a restrictive phase of emergent and urgent vascular procedures occurred. The Society for Vascular Surgery Patient Safety Organization queried both data managers and physicians in May 2020. Approximately three-fourths (74%) of physicians adopted restrictive operating policies for urgent and emergent cases only, whereas one-half proceeded with "time sensitive" elective cases as urgent...
September 2021: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://read.qxmd.com/read/32860844/infective-endocarditis-in-patients-after-percutaneous-pulmonary-valve-implantation-with-the-stent-mounted-bovine-jugular-vein-valve-clinical-experience-and-evaluation-of-the-modified-duke-criteria
#23
JOURNAL ARTICLE
D Bos, D De Wolf, B Cools, B Eyskens, J Hubrechts, D Boshoff, J Louw, S Frerich, B Ditkowski, F Rega, B Meyns, W Budts, T Sluysmans, M Gewillig, R Heying
AIMS: Percutaneous pulmonary valve implantation (PPVI) has proven good hemodynamic results. As infective endocarditis (IE) remains a potential complication with limited available clinical data, we reviewed our patient records to improve future strategies of IE prevention, diagnosis and treatment. METHODS: Medical records of all patients diagnosed with Melody® valve IE according to the modified Duke criteria were retrospectively analyzed in three Belgian tertiary centers...
January 15, 2021: International Journal of Cardiology
https://read.qxmd.com/read/32215562/an-outreach-rehabilitation-program-for-nursing-home-residents-after-hip-fracture-may-be-cost-saving
#24
JOURNAL ARTICLE
Lauren A Beaupre, Doug Lier, Jay S Magaziner, C Allyson Jones, D William C Johnston, Donna M Wilson, Sumit R Majumdar
BACKGROUND: We compared the cost-effectiveness of 10 weeks of outreach rehabilitation (intervention) versus usual care (control) for ambulatory nursing home residents after hip fracture. METHODS: Enrollment occurred February 2011 through June 2015 in a Canadian metropolitan region. 77 participants were allocated in a 2:1 ratio to receive a 10-week rehabilitation program (intervention) or usual care (control) (46 intervention; 31 control). Using a payer perspective, we performed main and sensitivity analyses...
March 26, 2020: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://read.qxmd.com/read/31923817/interventions-designed-to-improve-the-safety-and-quality-of-therapeutic-anticoagulation-in-an-inpatient-electronic-medical-record
#25
REVIEW
Jodie Austin, Michael Barras, Clair Sullivan
IMPORTANCE: Anticoagulants are high-risk medications with the potential to cause significant patient harm or death. Digital transformation is occurring in hospital practice and it is essential to implement effective, evidence-based strategies for these medications in an electronic medical record (EMR). OBJECTIVE: To systematically appraise the literature to determine which EMR interventions have improved the safety and quality of therapeutic anticoagulation in an inpatient hospital setting...
March 2020: International Journal of Medical Informatics
https://read.qxmd.com/read/31800416/anesthesia-hazards-and-the-impact-of-physician-re-entry
#26
REVIEW
Elvera L Baron, Garrett Burnett, Katherine Loftus, Marc Sherwin, Daniel Katz, Adam I Levine
No abstract text is available yet for this article.
2020: International Anesthesiology Clinics
https://read.qxmd.com/read/31756386/the-role-of-amiodarone-in-contemporary-management-of-complex-cardiac-arrhythmias
#27
REVIEW
Nebojša Mujović, Dobromir Dobrev, Milan Marinković, Vincenzo Russo, Tatjana S Potpara
Amiodarone is an iodinated benzofuran derivative, a highly lipophilic drug with unpredictable pharmacokinetics. Although originally classified as a class III agent due to its ability to prolong refractoriness in cardiac regions and prevent/terminate re-entry, amiodarone shows antiarrhythmic properties of all four antiarrhythmic drug classes. Amiodarone is a potent coronary and peripheral vasodilator and can be safely used in patients with left ventricular dysfunction after myocardial infarction or those with congestive heart failure or hypertrophic cardiomyopathy...
January 2020: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://read.qxmd.com/read/31472983/identifying-low-value-pathology-test-ordering-in-hospitalised-patients-a-retrospective-cohort-study-across-two-hospitals
#28
JOURNAL ARTICLE
Alexis Hure, Kerrin Palazzi, Roseanne Peel, David Geraghty, Phillip Collard, Theo De Malmanche, Huy Tran, Penny Reeves, Andrew Searles, Louisa Jorm, John Attia
The push to identify low value care has led to scrutiny of pathology test re-ordering. The objective of this study was to identify the patterns of ordering pathology tests among inpatients in teaching hospitals and model strategies to reduce unnecessary testing. This was a retrospective cohort study of all adult medical and surgical inpatients admitted to one major teaching hospital and one rural hospital in the same health district over 2 years. Obstetric, gynaecological, intensive care, elective/day procedures and dialysis admissions were excluded...
October 2019: Pathology
https://read.qxmd.com/read/31229187/expanding-low-threshold-buprenorphine-to-justice-involved-individuals-through-mobile-treatment-addressing-a-critical-care-gap
#29
JOURNAL ARTICLE
Noa Krawczyk, Megan Buresh, Michael S Gordon, Thomas R Blue, Michael I Fingerhood, Deborah Agus
BACKGROUND: Opioid use disorder (OUD) is highly prevalent among justice-involved individuals. While risk for overdose and other adverse consequences of opioid use are heightened among this population, most justice-involved individuals and other high-risk groups experience multiple barriers to engagement in opioid agonist treatment. METHODS: This paper describes the development of Project Connections at Re-Entry (PCARE), a low-threshold buprenorphine treatment program that engages vulnerable patients in care through a mobile van parked directly outside the Baltimore City Jail...
August 2019: Journal of Substance Abuse Treatment
https://read.qxmd.com/read/30922752/double-homemade-fenestrated-stent-graft-for-total-endovascular-aortic-arch-repair
#30
JOURNAL ARTICLE
Ludovic Canaud, Baris Ata Ozdemir, Lucien Chassin-Trubert, Julien Sfeir, Pierre Alric, Thomas Gandet
OBJECTIVE: The aim of this retrospective analysis was to evaluate the outcomes of physician-modified double fenestrated stent grafts for total endovascular aortic arch repair: one proximal large fenestration for the brachiocephalic trunk and the left common carotid artery and one distal fenestration for the left subclavian artery (LSA). METHODS: From January 2017 through February 2018, 17 patients (88.2% elective) underwent thoracic endovascular aortic repair (TEVAR) with double homemade fenestrated stent graft for total endovascular aortic arch repair to maintain supra-aortic trunk patency...
October 2019: Journal of Vascular Surgery
https://read.qxmd.com/read/30901774/-determinants-of-leaving-and-resumption-of-medical-profession-a-qualitative-study-with-former-participants-in-a-re-entry-seminar
#31
JOURNAL ARTICLE
Anna-Lena Dávila Izaguirre, Dagmar Schneider, Jost Steinhäuser
BACKGROUND: There is an increasing demand for physicians in Germany. At the same time, there are many licensed doctors who are not actively working as physicians. To win them back to their original field of expertise would be a policy to bring doctors into the health care system in a timely manner. The aims of this study were therefore, on the one hand, to explore individual reasons for leaving the medical profession and for deciding to return to the medical profession. Furthermore, the value of participating in a re-entry seminar was assessed in this process...
March 22, 2019: Das Gesundheitswesen
https://read.qxmd.com/read/30901432/characteristics-of-iraqi-patients-treated-during-operation-inherent-resolve-by-a-forward-surgical-team
#32
JOURNAL ARTICLE
Christina Hahn, Amanda M Staudt, Joel Brockmeyer, Elizabeth A Mann-Salinas, Jennifer M Gurney
INTRODUCTION: The combat experience during the re-entry stages of Operation Inherent Resolve was distinct from other recent operations, but there is no published literature regarding these "initial entry operations" experiences among forward surgical teams (FSTs) deployed to Role 2 facilities A descriptive analysis of patients treated by FSTs may provide valuable information for Role 2 surgical teams preparing to deploy in support of initial entry operations. The purpose of this analysis was to describe injury mechanism, wounding patterns and interventions performed by a small FST in the re-entry phase in Iraq...
March 1, 2019: Military Medicine
https://read.qxmd.com/read/30041703/physician-delivered-motivational-interviewing-to-improve-adherence-and-retention-in-care-among-challenging-hiv-infected-patients-in-argentina-copa2-study-protocol-for-a-cluster-randomized-controlled-trial
#33
JOURNAL ARTICLE
Omar Sued, Isabel Cassetti, Diego Cecchini, Pedro Cahn, Lina Bofill de Murillo, Stephen M Weiss, Lissa N Mandell, Manasi Soni, Deborah L Jones
BACKGROUND: "Challenging" HIV-infected patients, those not retained in treatment, represent a critical focus for positive prevention, as linkage to care, early initiation of antiretroviral therapy, adherence and retention in treatment facilitate viral suppression, thus optimizing health and reducing HIV transmission. Argentina was one of the first Latin American countries to guarantee HIV prevention, diagnosis and comprehensive care services, including antiretroviral medication, which removed cost and access as barriers...
July 24, 2018: Trials
https://read.qxmd.com/read/29187329/impact-of-therapeutic-education-with-a-written-document-on-treatments-knowledge-and-adherence-among-elderly-patients-results-of-a-pilot-study
#34
JOURNAL ARTICLE
Claire Vanhaecke Collard, Laetitia Michaut, Florian Caillierez, Daniel Parra, Marc Bonnefoy
Olders patients are exposed to iatrogenic risk as they are often frail, with multiple pathologies and therefore polymedicated. The objective of this study was to evaluate the knowledge of treatment in the elderly before and after a time of oral therapeutic education accompanied by the submission of a written educational support. The impact of that education on the adhesion was also evaluated. METHODS: We've included patients aged at least 75 years old, living at home, and managing themselves their treatment...
December 1, 2017: Gériatrie et Psychologie Neuropsychiatrie du Vieillissement
https://read.qxmd.com/read/29176456/appropriate-use-of-laboratory-test-requests-in-the-emergency-department-a-multilevel-intervention
#35
JOURNAL ARTICLE
Peiman Nazerian, Simone Vanni, Alessandra Fanelli, Linda Fallai, Cesare Duranti, Agostino Ognibene, Stefano Rapi, Laura Betti, Matteo Tomaiuolo, Calamai Monica, Stefano Grifoni
OBJECTIVE: Laboratory test requests in the emergency department (ED) are increasing worldwide. We evaluated whether a multilevel intervention on the basis of the optimization of test profiles and educational meetings with physicians could reduce the number of tests ordered. PATIENTS AND METHODS: In a single-center before and after study design, the 8-month intervention period was compared with the 8-month preintervention period. Laboratory test profiles were reduced from 6 to 2 and the number of tests in each profile was reduced by 50%...
November 24, 2017: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
https://read.qxmd.com/read/29170987/from-girlhood-to-motherhood-rituals-of-childbirth-and-obstetrical-medicine-re-examined-through-john-milton
#36
JOURNAL ARTICLE
Ashleigh Frayne
This article considers how seventeenth-century writer John Milton engages in modes of thinking that register the obstetric revolution occurring during the period. During a time when physicians were gaining entry to the birthing room, a medical rhetoric of childbirth was developing that cast childbirth in new pathological terms. Milton's A Masque Presented at Ludlow Castle demonstrates how childbirth was influenced by emerging obstetrical language and practice, as well as the ways in which a writer might question such influence...
November 23, 2017: Journal of Medical Humanities
https://read.qxmd.com/read/28190702/analysis-of-low-appropriateness-score-exam-trends-in-decision-support-based-radiology-order-entry-system
#37
JOURNAL ARTICLE
Supriya Gupta, Kandace Klein, Anand H Singh, James H Thrall
PURPOSE: Awareness of imaging utilization increased after implementation of Radiology Order Entry with decision support systems (ROE-DS). Our hypothesis is few exams with low Clinical Appropriateness Score (CAS) on ROE-DS are performed. Clinical indications of exams with CAS less than 3 (9-point scale) were re-reviewed and reports analyzed. MATERIALS AND METHODS: Structured Query Language-based query retrieved exams with CAS less than 3 in ROE-DS from January 2007 to December 2011...
May 2017: Journal of the American College of Radiology: JACR
https://read.qxmd.com/read/28152815/development-of-an-integrated-practice-unit-utilizing-a-lean-approach-to-impact-value-of-care-for-brain-tumor-patients
#38
JOURNAL ARTICLE
Christine Ahn, Preston White, Linda M Liau, Timothy Francis Cloughesy, Phioanh Leia Nghiemphu
99 Background: Lack of care coordination across subspecialty departments involved in the treatment of brain tumor patients at our institution has negatively impacted patient outcomes, patient experience, and costs. Meanwhile, value-based health care has become increasingly relevant as a means to respond to changing payment structures and improve quality. With the aim to increase value, we restructured medical practice across the continuum of care for brain tumor patients by developing a virtual (non co-located) Integrated Practice Unit (IPU)...
March 2016: Journal of Clinical Oncology
https://read.qxmd.com/read/28108091/implementation-of-a-simple-innovative-system-for-postprescription-antibiotic-review-based-on-computerized-tools-with-shared-access
#39
JOURNAL ARTICLE
F Bouchand, A Dinh, A L Roux, B Davido, H Michelon, M Lepainteur, B Legendre, F El Sayed, I Pierre, J Salomon, C Lawrence, C Perronne, M Villart, A-C Crémieux
BACKGROUND: Controlling antibiotic use in healthcare establishments limits their consumption and the emergence of bacterial resistance. AIM: To evaluate the efficiency of an innovative antibiotic stewardship strategy implemented over three years in a university hospital. METHODS: An antimicrobial multi-disciplinary team (AMT) [pharmacist, microbiologist and infectious disease specialist (IDS)] conducted a postprescription review. Specific coding of targeted antibiotics (including broad-spectrum β-lactams, glycopeptides, lipopeptides, fluoroquinolones and carbapenems) in the computerized physician order entry allowed recording of all new prescriptions...
March 2017: Journal of Hospital Infection
https://read.qxmd.com/read/27756401/the-use-of-a-policy-dialogue-to-facilitate-evidence-informed-policy-development-for-improved-access-to-care-the-case-of-the-winnipeg-central-intake-service-wcis
#40
JOURNAL ARTICLE
Zaheed Damani, Gail MacKean, Eric Bohm, Brie DeMone, Brock Wright, Tom Noseworthy, Jayna Holroyd-Leduc, Deborah A Marshall
BACKGROUND: Policy dialogues are critical for developing responsive, effective, sustainable, evidence-informed policy. Our multidisciplinary team, including researchers, physicians and senior decision-makers, comprehensively evaluated The Winnipeg Central Intake Service, a single-entry model in Winnipeg, Manitoba, to improve patient access to hip/knee replacement surgery. We used the evaluation findings to develop five evidence-informed policy directions to help improve access to scheduled clinical services across Manitoba...
October 18, 2016: Health Research Policy and Systems
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