Suradet Buttachon, Alice A Ramos, Ângela Inácio, Tida Dethoup, Luís Gales, Michael Lee, Paulo M Costa, Artur M S Silva, Nazim Sekeroglu, Eduardo Rocha, Madalena M M Pinto, José A Pereira, Anake Kijjoa
A previously unreported bis -indolyl benzenoid, candidusin D ( 2e ) and a new hydroxypyrrolidine alkaloid, preussin C ( 5b ) were isolated together with fourteen previously described compounds: palmitic acid, clionasterol, ergosterol 5,8-endoperoxides, chrysophanic acid ( 1a ), emodin ( 1b ), six bis -indolyl benzenoids including asterriquinol D dimethyl ether ( 2a ), petromurin C ( 2b ), kumbicin B ( 2c ), kumbicin A ( 2d ), 2″-oxoasterriquinol D methyl ether ( 3 ), kumbicin D ( 4 ), the hydroxypyrrolidine alkaloid preussin ( 5a ), (3 S , 6 S )-3,6-dibenzylpiperazine-2,5-dione ( 6 ) and 4-(acetylamino) benzoic acid ( 7 ), from the cultures of the marine sponge-associated fungus Aspergillus candidus KUFA 0062...
April 6, 2018: Marine Drugs