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https://www.readbyqxmd.com/read/28550701/patient-centred-care-in-canada-key-components-and-the-path-forward
#1
Terrence Montague, Amédé Gogovor, John Aylen, Lisa Ashley, Sara Ahmed, Lesli Martin, Bonnie Cochrane, Owen Adams, Joanna Nemis-White
Canadians' health and its care continue to evolve. Chronic diseases affect more than 50% of our aging population, but the majority of public and professional stakeholders retain a sense of care quality. An emergent issue, however, is generating an increasingly wide debate. It is the concept of patient-centred care, including its definition of key components, and efficacy. To advance the evidence base, the 2013-2014 and 2016 Health Care in Canada (HCIC) surveys measured pan-stakeholder levels of support and implementation priorities for frequently proposed components of patient centricity in healthcare...
2017: Healthcare Quarterly
https://www.readbyqxmd.com/read/28550649/improved-formula-see-text-determination-in-23-na-35-cl-and-17-o-mri-using-iterative-partial-volume-correction-based-on-1-h-mri-segmentation
#2
Sebastian C Niesporek, Reiner Umathum, Thomas M Fiedler, Peter Bachert, Mark E Ladd, Armin M Nagel
OBJECTIVE: Functional parameters can be measured with the help of quantitative non-proton MRI where exact relaxometry parameters are needed. Investigation of [Formula: see text] is often biased by strong partial volume (PV) effects. Hence, in this work a PV correction algorithm approach was evaluated that uses iteratively adapted [Formula: see text]-values and high-resolution structural (1)H data to determine transverse relaxation in non-proton MRI more accurately. MATERIALS AND METHODS: Simulations, a phantom study and in vivo (23)Na, (17)O and (35)Cl MRI measurements of five healthy volunteers were performed to evaluate the algorithm...
May 26, 2017: Magma
https://www.readbyqxmd.com/read/28550518/racial-ethnic-differences-in-perception-of-need-for-mental-health-treatment-in-a-us-national-sample
#3
Joshua Breslau, Matthew Cefalu, Eunice C Wong, M Audrey Burnam, Gerald P Hunter, Karen R Florez, Rebecca L Collins
PURPOSE: To resolve contradictory evidence regarding racial/ethnic differences in perceived need for mental health treatment in the USA using a large and diverse epidemiologic sample. METHODS: Samples from 6 years of a repeated cross-sectional survey of the US civilian non-institutionalized population were combined (N = 232,723). Perceived need was compared across three non-Hispanic groups (whites, blacks and Asian-Americans) and two Hispanic groups (English interviewees and Spanish interviewees)...
May 26, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28550480/characteristics-associated-with-quality-of-life-among-people-with-drug-resistant-epilepsy
#4
Leone Ridsdale, Gabriella Wojewodka, Emily Robinson, Sabine Landau, Adam Noble, Stephanie Taylor, Mark Richardson, Gus Baker, Laura H Goldstein
Quality of Life (QoL) is the preferred outcome in non-pharmacological trials, but there is little UK population evidence of QoL in epilepsy. In advance of evaluating an epilepsy self-management course we aimed to describe, among UK participants, what clinical and psycho-social characteristics are associated with QoL. We recruited 404 adults attending specialist clinics, with at least two seizures in the prior year and measured their self-reported seizure frequency, co-morbidity, psychological distress, social characteristics, including self-mastery and stigma, and epilepsy-specific QoL (QOLIE-31-P)...
May 26, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28550470/hormonal-and-morphological-changes-during-seed-development-of-cypripedium-japonicum
#5
Xiaona Yan, Min Tian, Fen Liu, Caixia Wang, Ying Zhang
With the goal of evaluating the factors that may be influencing the reproductive success of an endangered, terrestrial orchid Cypripedium japonicum Thunb., the anatomical and morphological characteristics of seed development were assessed, as were the levels of endogenous hormones to investigate the possible relationship between hormones and seed development. The results showed that morphological characteristics of seeds were changing from milky white and filiform to brown and fusiform. The development of ovule that initiated on the fertile valves only began after pollination, and a mature embryo sac was produced at 40 days after pollination (DAP)...
May 27, 2017: Protoplasma
https://www.readbyqxmd.com/read/28550424/depression-and-antidepressant-use-among-asian-and-hispanic-adults-association-with-immigrant-generation-and-language-use
#6
Ping Chen, Jon M Hussey, Timothy O Monbureau
This research investigates the psychological well-being and usage of medical treatments by Asian and Hispanic immigrant descendants. Using data from all four waves of Add Health study, this paper focuses on two outcomes: (1) depression and (2) levels of antidepressant use by race/ethnicity, immigrant generation, and linguistic acculturation levels during adulthood. Findings reveal that depression is prevalent among Mexican Americans, other Hispanics, and Asian Americans. Furthermore, Mexican Americans and Asian Americans have reported a lower level of antidepressant use than whites, with Asian Americans attaining the lowest level when immigrant generation, language acculturation levels, and other socioeconomic factors are held constant...
May 26, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28550285/scale-integrated-network-hubs-of-the-white-matter-structural-network
#7
Hunki Kwon, Yong-Ho Choi, Sang Won Seo, Jong-Min Lee
The 'human connectome' concept has been proposed to significantly increase our understanding of how functional brain states emerge from their underlying structural substrates. Especially, the network hub has been considered one of the most important topological properties to interpret a network as a complex system. However, previous structural brain connectome studies have reported network hub regions based on various nodal resolutions. We hypothesized that brain network hubs should be determined considering various nodal scales in a certain range...
May 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28550279/cinnamon-induces-browning-in-subcutaneous-adipocytes
#8
Hiu Yee Kwan, Jiahui Wu, Tao Su, Xiao-Juan Chao, Bin Liu, Xiuqiong Fu, Chi Leung Chan, Rebecca Hiu Ying Lau, Anfernee Kai Wing Tse, Quan Bin Han, Wang Fun Fong, Zhi-Ling Yu
Browning is the process of increasing the number of brite cells, which helps to increase energy expenditure and reduce obesity. Consumption of natural and non-toxic herbal extracts that possess the browning effect is an attractive anti-obesity strategy. In this study, we examined the browning effect of cinnamon extract. We found that cinnamon extract (CE) induced typical brown adipocyte multiocular phenotype in 3T3-L1 adipocytes. The treatment also increased brown adipocytes markers and reduced white adipocytes markers in the 3T3-L1 adipocytes...
May 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28550194/the-risk-of-severe-hypoglycemia-in-type-1-diabetes-over-30-years-of-follow-up-in-the-dcct-edic-study
#9
Rose A Gubitosi-Klug, Barbara H Braffett, Neil H White, Robert S Sherwin, F John Service, John M Lachin, William V Tamborlane
OBJECTIVE: During the DCCT, intensive diabetes therapy achieving a mean HbA1c of ∼7% was associated with a threefold increase in the rate of severe hypoglycemia (defined as requiring assistance) compared with conventional diabetes therapy with a mean HbA1c of 9% (61.2 vs. 18.7 per 100 patient-years). After ∼30 years of follow-up, we investigated the rates of severe hypoglycemia in the DCCT/EDIC cohort. RESEARCH DESIGN AND METHODS: Rates of severe hypoglycemia were reported quarterly during DCCT and annually during EDIC (i...
May 26, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28550082/primary-membranous-nephropathy
#10
William G Couser
Membranous nephropathy (MN) is a unique glomerular lesion that is the most common cause of idiopathic nephrotic syndrome in nondiabetic white adults. About 80% of cases are renal limited (primary MN, PMN) and 20% are associated with other systemic diseases or exposures (secondary MN). This review focuses only on PMN. Most cases of PMN have circulating IgG4 autoantibody to the podocyte membrane antigen PLA2R (70%), biopsy evidence PLA2R staining indicating recent immunologic disease activity despite negative serum antibody levels (15%), or serum anti-THSD7A (3%-5%)...
May 26, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28550078/race-and-gender-differences-in-undergraduate-research-mentoring-structures-and-research-outcomes
#11
Melissa L Aikens, Melissa M Robertson, Sona Sadselia, Keiana Watkins, Mara Evans, Christopher R Runyon, Lillian T Eby, Erin L Dolan
Participating in undergraduate research with mentorship from faculty may be particularly important for ensuring the persistence of women and minority students in science. Yet many life science undergraduates at research universities are mentored by graduate or postdoctoral researchers (i.e., postgraduates). We surveyed a national sample of undergraduate life science researchers about the mentoring structure of their research experiences and the outcomes they realized from participating in research. We observed two common mentoring structures: an open triad with undergraduate-postgraduate and postgraduate-faculty ties but no undergraduate-faculty tie, and a closed triad with ties among all three members...
2017: CBE Life Sciences Education
https://www.readbyqxmd.com/read/28550009/digital-support-interventions-for-the-self-management-of-low-back-pain-a-systematic-review
#12
Barbara I Nicholl, Louise F Sandal, Mette J Stochkendahl, Marianne McCallum, Nithya Suresh, Ottar Vasseljen, Jan Hartvigsen, Paul J Mork, Per Kjaer, Karen Søgaard, Frances S Mair
BACKGROUND: Low back pain (LBP) is a common cause of disability and is ranked as the most burdensome health condition globally. Self-management, including components on increased knowledge, monitoring of symptoms, and physical activity, are consistently recommended in clinical guidelines as cost-effective strategies for LBP management and there is increasing interest in the potential role of digital health. OBJECTIVE: The study aimed to synthesize and critically appraise published evidence concerning the use of interactive digital interventions to support self-management of LBP...
May 21, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28549981/early-pregnancy-vaginal-microbiome-trends-and-preterm-birth
#13
Molly J Stout, Yanjiao Zhou, Kristine M Wylie, Phillip I Tarr, George A Macones, Methodius G Tuuli
BACKGROUND: Despite decades of attempts to link infectious agents to preterm birth, an exact causative microbe or community of microbes remains elusive. Non-culture 16S ribosomal RNA gene sequencing suggests important racial differences and pregnancy specific changes in the vaginal microbial communities. A recent study examining the association of the vaginal microbiome and preterm birth documented important findings but was performed in a predominantly White cohort. Given the important racial differences in bacterial communities within the vagina as well as persistent racial disparities in preterm birth it is important to examine cohorts with varied demographic compositions...
May 23, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28549883/a-non-iterative-multi-scale-approach-for-intensity-inhomogeneity-correction-in-mri
#14
Maryjo M George, S Kalaivani, M S Sudhakar
Intensity inhomogeneity is the prime obstacle for MR image processing like automatic segmentation, registration etc. This complication has strong dependence on the associated acquisition hardware and patient anatomy which recommends retrospective correction. In this paper, a new method is developed for correcting the intensity inhomogeneity using a non-iterative multi-scale approach that doesn't necessitate segmentation and any prior knowledge on the scanner or subject. The proposed algorithm extracts bias field at different scales using a Log-Gabor filter bank followed by smoothing operation...
May 23, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28549858/a-prospective-observational-cohort-study-to-assess-the-incidence-of-acute-otitis-media-among-children-0-5-years-of-age-in-southern-brazil
#15
Tatiana M Lanzieri, Clóvis Arns da Cunha, Rejane B Cunha, D Fermin Arguello, Raghavendra Devadiga, Nervo Sanchez, Eduardo Ortega Barria
OBJECTIVES: To estimate acute otitis media (AOM) incidence among young children and impact on quality of life of parents/caregivers in a southern Brazilian city. METHODS: Prospective cohort study including children 0-5 years of age registered at a private pediatric practice. AOM episodes diagnosed by a pediatrician and impact on quality of life of parents/caregivers were assessed during a 12-month follow-up. RESULTS: During September 2008-March 2010, of 1136 children enrolled in the study, 1074 (95%) were followed: 55...
May 23, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28549853/molecular-fingerprinting-of-principal-neurons-in-the-rodent-hippocampus-a-neuroinformatics-approach
#16
D J Hamilton, C M White, C L Rees, D W Wheeler, G A Ascoli
Neurons are often classified by their morphological and molecular properties. The online knowledge base Hippocampome.org primarily defines neuron types from the rodent hippocampal formation based on their main neurotransmitter (glutamate or GABA) and the spatial distributions of their axons and dendrites. For each neuron type, this open-access resource reports any and all published information regarding the presence or absence of known molecular markers, including calcium-binding proteins, neuropeptides, receptors, channels, transcription factors, and other molecules of biomedical relevance...
April 29, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28549815/the-hispanic-paradox-in-endometrial-cancer-a-national-cancer-database-study
#17
Erica M Malagon-Blackwell, Brandon-Luke L Seagle, Wilberto Nieves-Neira, Shohreh Shahabi
OBJECTIVE: To compare the overall survival of non-Hispanic white and Hispanic women with endometrial cancer. METHODS: We performed an observational retrospective cohort study of Hispanic and non-Hispanic women with endometrial cancer from the 2004-2014 National Cancer Database. Baseline characteristics were compared with the Chi-squared test for categorical variables or the Mann-Whitney U test for ordinal or continuous variables. The Kaplan-Meier method was used to estimate unadjusted survival times, which were compared with the log-rank test...
May 23, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28549796/development-of-the-error-monitoring-system-from-ages-9-35-unique-insight-provided-by-mri-constrained-source-localization-of-eeg
#18
George A Buzzell, John E Richards, Lauren K White, Tyson V Barker, Daniel S Pine, Nathan A Fox
The ability to self-detect errors and dynamically adapt behavior is a cornerstone of higher-level cognition, requiring coordinated activity from a network of neural regions. However, disagreement exists over how the error-monitoring system develops throughout adolescence and early adulthood. The present report leveraged MRI-constrained EEG source localization to detail typical development of the error-monitoring system in a sample of 9-35 year-olds (n=43). Participants performed a flanker task while high-density EEG was recorded; structural MRIs were also acquired for all participants...
May 23, 2017: NeuroImage
https://www.readbyqxmd.com/read/28549795/brain-grey-and-white-matter-predictors-of-verbal-ability-traits-in-older-age-the-lothian-birth-cohort-1936
#19
Paul Hoffman, Simon R Cox, Dominika Dykiert, Susana Muñoz Maniega, Maria C Valdés Hernández, Mark E Bastin, Joanna M Wardlaw, Ian J Deary
Cerebral grey and white matter MRI parameters are related to general intelligence and some specific cognitive abilities. Less is known about how structural brain measures relate specifically to verbal processing abilities. We used multi-modal structural MRI to investigate the grey matter (GM) and white matter (WM) correlates of verbal ability in 556 healthy older adults (mean age = 72.68 years, s.d. = 0.72 years). Structural equation modelling was used to decompose verbal performance into two latent factors: a storage factor that indexed participants' ability to store representations of verbal knowledge and an executive factor that measured their ability to regulate their access to this information in a flexible and task-appropriate manner...
May 23, 2017: NeuroImage
https://www.readbyqxmd.com/read/28549741/association-between-weather-seasonality-and-blood-parameters-in-riverine-populations-of-the-brazilian-amazon
#20
Poliany C O Rodrigues, Eliane Ignotti, Sandra S Hacon
OBJECTIVE: To analyze the seasonality of blood parameters related to iron homeostasis, inflammation, and allergy in two riverine populations from the Brazilian Amazon. METHODS: This was a cross-sectional study of 120 children and adolescents of school age, living in riverine communities of Porto Velho, Rondonia, Brazil, describing the hematocrit, hemoglobin, ferritin, serum iron, total white blood cell count, lymphocytes, eosinophils, C-reactive protein, and immunoglobulin E levels in the dry and rainy seasons...
May 23, 2017: Jornal de Pediatria
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