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https://www.readbyqxmd.com/read/28961503/lignin-and-ethylcellulose-in-controlled-release-formulations-to-reduce-leaching-of-chloridazon-and-metribuzin-in-light-textured-soils
#1
F Flores-Céspedes, I Daza-Fernández, M Villafranca-Sánchez, M Fernández-Pérez, E Morillo, T Undabeytia
In this research, controlled release formulations (CRFs) of the herbicides chloridazon and metribuzin, identified as potential leachers, have been evaluated in soils with different texture. To prepare the CRFs, ethylcellulose (EC) and dibutylsebacate (DBS) have been used as coating agents in lignin-polyethylene glycol based formulations. Mobility experiments have been carried out in two light textured soils (sandy and sandy-loam). Breakthrough curves have shown that the use of CRFs reduces the presence of chloridazon and metribuzin in the leachate compared to technical and commercial products, being the lignin CRF coated with EC and DBS the most efficient to diminish the herbicide leaching...
September 20, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28928514/component-analysis-of-nutritionally-rich-chloroplasts-recovery-from-conventional-and-unconventional-green-plant-species
#2
Mohamed A Gedi, Rhianna Briars, Felius Yuseli, Noorazwani Zainol, Randa Darwish, Andrew M Salter, David A Gray
A study of the literature indicates that chloroplasts synthesise a range of molecules, many of which have nutritional value for humans, but the nutritional credentials of chloroplasts recovered from plant cells are not established. Chloroplast-rich-fractions (CRFs) were prepared from green plant species and the macro- and micro-nutrient composition compared with the whole leaf materials (WLMs). The results indicated that, on a dry weight basis, CRF material from a range of green biomass was enriched in lipids and proteins, and in a range of micronutrients compared with the WLM...
August 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28887088/impact-of-the-heart-rate-on-the-shape-of-the-cardiac-response-function
#3
Feliberto de la Cruz, Andy Schumann, Stefanie Köhler, Karl-Jürgen Bär, Gerd Wagner
There is limited understanding about how heart rate (HR) influences the blood-oxygen level dependent (BOLD) signal. While the mechanism by which respiration induces fluctuation in the BOLD signal is relatively well understood, the mechanisms regarding the HR remains unclear. The application of canonical cardiac response function (CRF), or subject-specific CRF, is an effective method for creating nuisance regressors, which can be used to remove cardiac-induced fluctuations in the BOLD signal. However, the relationship between physiological parameters and the characteristics of the CRF has not been systematically investigated...
September 5, 2017: NeuroImage
https://www.readbyqxmd.com/read/28809107/synthesis-and-insecticidal-activity-of-enzyme-triggered-functionalized-hollow-mesoporous-silica-for-controlled-release
#4
Amir E Kaziem, Yunhao Gao, Shun He, Jianhong Li
In the present study, enzymatic responsive controlled release formulations (CRFs) were fabricated. The CRFs were achieved by anchoring mechanically interlocked molecules using α-cyclodextrin onto the surface pore rims of hollow mesoporous silica (HMS). The CRFs were characterized using Fourier transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, and thermogravimetric analysis. The results showed that the CRFs had extraordinary loading ability for chlorantraniliprole (42% w/w) and could effectively preserve chlorantraniliprole against degradation under thermal conditions and UV radiation...
September 13, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28766397/diagnostic-accuracy-of-non-contrast-abdominal-ct-scans-performed-as-follow-up-for-patients-with-an-established-cancer-diagnosis-a-retrospective-study
#5
Hassan Semaan, Mohamad F Bazerbashi, Geoffrey Siesel, Paul Aldinger, Tawfik Obri
OBJECTIVES: To determine the accuracy and non-detection rate of cancer related findings (CRFs) on follow-up non-contrast-enhanced CT (NECT) versus contrast-enhanced CT (CECT) images of the abdomen in patients with a known cancer diagnosis. METHODS: A retrospective review of 352 consecutive CTs of the abdomen performed with and without IV contrast between March 2010 and October 2014 for follow-up of cancer was included. Two radiologists independently assessed the NECT portions of the studies...
August 2, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28731404/jackson-pratt-drainage-in-pediatric-craniofacial-reconstructive-surgery-is-it-helping-or-hurting
#6
Kumar Vasudevan, Ahyuda Oh, R Shane Tubbs, David Garcia, Andrew Reisner, Joshua J Chern
OBJECTIVE Jackson-Pratt drains (JPDs) are commonly employed in pediatric craniofacial reconstructive surgery (CRFS) to reduce postoperative wound complications, but their risk profile remains unknown. Perioperative blood loss and volume shifts are major risks of CFRS. The goal of this study was to evaluate the risks of JPD usage in CFRS, particularly with regard to perioperative blood loss, hyponatremia, intensive care unit (ICU) length of stay, and postoperative wound complications. METHODS The authors performed a retrospective review of data obtained in pediatric patients who underwent CFRS at a single institution, as performed by multiple surgeons between January 2010 and December 2014...
October 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28727775/adolescent-health-in-rural-ghana-a-cross-sectional-study-on-the-co-occurrence-of-infectious-diseases-malnutrition-and-cardio-metabolic-risk-factors
#7
Marie Alicke, Justice K Boakye-Appiah, Inusah Abdul-Jalil, Andrea Henze, Markus van der Giet, Matthias B Schulze, Florian J Schweigert, Frank P Mockenhaupt, George Bedu-Addo, Ina Danquah
In sub-Saharan Africa, infectious diseases and malnutrition constitute the main health problems in children, while adolescents and adults are increasingly facing cardio-metabolic conditions. Among adolescents as the largest population group in this region, we investigated the co-occurrence of infectious diseases, malnutrition and cardio-metabolic risk factors (CRFs), and evaluated demographic, socio-economic and medical risk factors for these entities. In a cross-sectional study among 188 adolescents in rural Ghana, malarial infection, common infectious diseases and Body Mass Index were assessed...
2017: PloS One
https://www.readbyqxmd.com/read/28719224/cardiometabolic-risk-factors-and-health-related-quality-of-life-in-adolescents-with-obesity
#8
Anna Pogodina, Ljubov Rychkova, Olga Kravtzova, Juliana Klimkina, Arjuna Kosovtzeva
BACKGROUND: A number of research studies have demonstrated a decrease in health-related quality of life (HRQL) measures among obese children. Moreover, the causes of HRQL impairments are not completely clear. Adolescent obesity is oftentimes associated with other cardiometabolic risk factors (CRFs); hence, the aim of our research was to estimate the frequency of CRFs and to determine whether there is an association between CRFs and HRQL scores among obese adolescents. METHODS: Our research included 92 treatment-seeking obese adolescents (11-17 years), 34 males...
July 18, 2017: Childhood Obesity
https://www.readbyqxmd.com/read/28710367/hyperuricemia-and-clustering-of-cardiovascular-risk-factors-in-the-chinese-adult-population
#9
Jie Wu, Ling Qiu, Xin-Qi Cheng, Tao Xu, Wei Wu, Xue-Jun Zeng, Yi-Cong Ye, Xiu-Zhi Guo, Qian Cheng, Qian Liu, Li Liu, Cheng-Li Xu, Guang-Jin Zhu
Hyperuricemia is common in China and the relevance of hyperuricemia and cardiovascular disease (CVD) risk has been highlighted, but to date there has been rarely nation-wide study in China. Here, we aim to estimate the current prevalence of hyperuricemia and evaluate the associations between hyperuricemia and cardiovascular risk factors (CRFs) clustering in a large sample of China adults including a plurality of ethnic minorities. Generally, a nationally representative sample of 22983 adults aged ≥18 years was recruited from 2007 to 2011...
July 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28701420/comparative-evaluation-of-subtyping-tools-for-surveillance-of-newly-emerging-hiv-1-strains
#10
Lavinia Fabeni, Giulia Berno, Joseph Fokam, Ada Bertoli, Claudia Alteri, Caterina Gori, Federica Forbici, Desiré Takou, Alessandra Vergori, Mauro Zaccarelli, Gaetano Maffongelli, Vanni Borghi, Alessandra Latini, Alfredo Pennica, Claudio Maria Mastroianni, Francesco Montella, Cristina Mussini, Massimo Andreoni, Andrea Antinori, Carlo Federico Perno, Maria Mercedes Santoro
HIV-1 non-B subtypes/circulating recombinant forms (CRFs) are increasing worldwide. Since subtype identification can be clinically relevant, we assessed the added value in HIV-1 subtyping using updated molecular phylogeny (Mphy) and the performance of routinely used automated tools. Updated Mphy (2015 updated reference sequences), used as a gold standard, was performed to subtype 13,116 HIV-1 protease/reverse transcriptase sequences and then compared with previous Mphy (reference sequences until 2014) and with COMET, REGA, SCUEAL, and Stanford subtyping tools...
September 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28684255/prescription-extraction-using-crfs-and-word-embeddings
#11
Carson Tao, Michele Filannino, Özlem Uzuner
In medical practices, doctors detail patients' care plan via discharge summaries written in the form of unstructured free texts, which among the others contain medication names and prescription information. Extracting prescriptions from discharge summaries is challenging due to the way these documents are written. Handwritten rules and medical gazetteers have proven to be useful for this purpose but come with limitations on performance, scalability, and generalizability. We instead present a machine learning approach to extract and organize medication names and prescription information into individual entries...
August 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28679441/hiv-1-genetic-diversity-and-primary-drug-resistance-mutations-before-large-scale-access-to-antiretroviral-therapy-republic-of-congo
#12
Fabien Roch Niama, Nicole Vidal, Halimatou Diop-Ndiaye, Etienne Nguimbi, Gabriel Ahombo, Philippe Diakabana, Édith Sophie Bayonne Kombo, Pembe Issamou Mayengue, Simon-Charles Kobawila, Henri Joseph Parra, Coumba Toure-Kane
BACKGROUND: In this work, we investigated the genetic diversity of HIV-1 and the presence of mutations conferring antiretroviral drug resistance in 50 drug-naïve infected persons in the Republic of Congo (RoC). Samples were obtained before large-scale access to HAART in 2002 and 2004. METHODS: To assess the HIV-1 genetic recombination, the sequencing of the pol gene encoding a protease and partial reverse transcriptase was performed and analyzed with updated references, including newly characterized CRFs...
July 5, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28628667/characterization-of-hiv-1-crf90_bf1-and-putative-novel-crfs_bf1-in-central-west-north-and-northeast-brazilian-regions
#13
Mônica Nogueira da Guarda Reis, Gonzalo Bello, Monick Lindenmeyer Guimarães, Mariane Martins Araújo Stefani
The Brazilian AIDS epidemic has been characterized by an increasing rate of BF1 recombinants and so far eight circulating recombinant forms/CRFs_BF1 have been described countrywide. In this study, pol sequences (protease/PR, reverse transcriptase/RT) of 87 BF1 mosaic isolates identified among 828 patients living in six Brazilian States from three geographic regions (Central West, North, Northeast) were analyzed. Phylogenetic and bootscan analyses were performed to investigate the evolutionary relationship and mosaic structure of BF1 isolates...
2017: PloS One
https://www.readbyqxmd.com/read/28586300/assessment-of-the-clinical-utility-of-adding-common-single-nucleotide-polymorphism-genetic-scores-to-classical-risk-factor-algorithms-in-coronary-heart-disease-risk-prediction-in-uk-men
#14
Katherine E Beaney, Jackie A Cooper, Fotios Drenos, Steve E Humphries
BACKGROUND: Risk prediction algorithms for coronary heart disease (CHD) are recommended for clinical use. However, their predictive ability remains modest and the inclusion of genetic risk may improve their performance. METHODS: QRISK2 was used to assess CHD risk using conventional risk factors (CRFs). The performance of a 19 single nucleotide polymorphism (SNP) gene score (GS) for CHD including variants identified by genome-wide association study and candidate gene studies (weighted using the results from the CARDIoGRAMplusC4D meta-analysis) was assessed using the second Northwick Park Heart Study (NPHSII) of 2775 healthy UK men (284 cases)...
August 28, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28586246/characterization-of-a-new-hiv-1-crf01_ae-crf07_bc-recombinant-virus-in-guangxi-china
#15
Desheng Kong, Yan Wang, Chen Wang, Shujia Liang, Yi Feng, Yuhua Ruan, Yiming Shao, Liying Ma
Currently, more and more kinds of circulating recombinant forms (CRFs) and unique recombinant forms (URFs) were identified in China. A novel second-generation CCR5-tropic HIV-1 recombinant virus (GX2016EU09) was identified here, which was isolated from a HIV-1 infected man who had sex with men (MSM) in Guangxi, China. Phylogenetic analysis of near full-length genome (NFLG) showed that the novel HIV-1 recombinant GX2016EU09 clustered with CRF01_AE reference sequences, but set up a distinct branch. Recombinant analysis showed that the NFLG of GX2016EU09 composed of CRF01_AE (as the backbone) and CRF07_BC, with 9 recombination break points observed in the gag, pol, vif, vpr, tat, rev, vpu, env and nef regions...
June 6, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28574343/exploring-context-with-deep-structured-models-for-semantic-segmentation
#16
Guosheng Lin, Chunhua Shen, Anton van den Hengel, Ian Reid
We propose an approach for exploiting contextual information in semantic image segmentation, and particularly investigate the use of patch-patch context and patch-background context in deep CNNs. We formulate deep structured models by combining CNNs and Conditional Random Fields (CRFs) for learning the patch-patch context between image regions. Specifically, we formulate CNN-based pairwise potential functions to capture semantic correlations between neighboring patches. Efficient piecewise training of the proposed deep structured model is then applied in order to avoid repeated expensive CRF inference during the course of back propagation...
May 26, 2017: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://www.readbyqxmd.com/read/28536270/different-signal-enhancement-pathways-of-attention-and-consciousness-underlie-perception-in-humans
#17
Jeroen J A van Boxtel
It is not yet known whether attention and consciousness operate through similar or largely different mechanisms. Visual processing mechanisms are routinely characterized by measuring contrast response functions (CRFs). In this report, behavioral CRFs were obtained in humans (both males and females) by measuring afterimage durations over the entire range of inducer stimulus contrasts to reveal visual mechanisms behind attention and consciousness. Deviations relative to the standard CRF, i.e., gain functions, describe the strength of signal enhancement, which were assessed for both changes due to attentional task and conscious perception...
June 14, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28482717/radiation-therapy-improves-survival-in-patients-with-testicular-diffuse-large-b-cell-lymphoma
#18
Jennifer C Ho, Bouthaina S Dabaja, Sarah A Milgrom, Grace L Smith, Jay P Reddy, Ali Mazloom, Ken H Young, Lijuan Deng, L Jeffrey Medeiros, Wenli Dong, Pamela K Allen, Therese Y Andraos, Nathan H Fowler, Loretta J Nastoupil, Yasuhiro Oki, Luis E Fayad, Francesco Turturro, Sattva S Neelapu, Jason Westin, Fredrick B Hagemeister, Maria Alma Rodriguez, Chelsea C Pinnix
In 120 Stage I-IV testicular diffuse large B-cell lymphoma (DLBCL) patients treated from 1964 to 2015, we assessed the benefits of prophylactic contralateral testicular radiation (RT) and prophylactic central nervous system (CNS) therapy on overall, progression free, testicular relapse free, and CNS relapse free survival (OS, PFS, TRFS, and CRFS, respectively). Seventy percent of patients received RT, 53% received anthracyclines and rituximab (modern therapy), and 61% received CNS prophylaxis. On univariate analysis RT was associated with improved TRFS, PFS, and trended toward improved OS...
December 2017: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/28468996/temporally-evolving-gain-mechanisms-of-attention-in-macaque-area-v4
#19
Ilaria Sani, Elisa Santandrea, Maria Concetta Morrone, Leonardo Chelazzi
Cognitive attention and perceptual saliency jointly govern our interaction with the environment. Yet, we still lack a universally accepted account of the interplay between attention and luminance contrast, a fundamental dimension of saliency. We measured the attentional modulation of V4 neurons' contrast response functions (CRFs) in awake, behaving macaque monkeys and applied a new approach that emphasizes the temporal dynamics of cell responses. We found that attention modulates CRFs via different gain mechanisms during subsequent epochs of visually driven activity: an early contrast-gain, strongly dependent on prestimulus activity changes (baseline shift); a time-limited stimulus-dependent multiplicative modulation, reaching its maximal expression around 150 ms after stimulus onset; and a late resurgence of contrast-gain modulation...
August 1, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28468684/a-chronology-of-ratios-between-black-smoke-and-pm10-and-pm2-5-in-the-context-of-comparison-of-air-pollution-epidemiology-concentration-response-functions
#20
Mathew R Heal, Iain J Beverland
BACKGROUND: For many air pollution epidemiological studies in Europe, 'black smoke' (BS) was the only measurement available to quantify ambient particulate matter (PM), particularly for exposures prior to the mid-1990s when quantification via the PM10 and/or PM2.5 metrics was introduced. The aim of this work was to review historic BS and PM measurements to allow comparison of health concentration-response functions (CRF) derived using BS as the measure of exposure with CRFs derived using PM10 or PM2...
May 3, 2017: Environmental Health: a Global Access Science Source
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