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https://www.readbyqxmd.com/read/29773924/mercury-in-the-diatoms-of-various-ecological-formations
#1
Magdalena Bełdowska, Aleksandra Zgrundo, Justyna Kobos
Mercury is a neurotoxin, its main source in the human organism being fish and seafood. The first level in the marine food web is formed of planktonic and benthic photosynthetic microorganisms, which form a biofilm on the surface of the hard bottom (epilithon) or plants (epiphyton). They are carriers of nutritional as well as toxic substances and pass these on to subsequent levels of the trophic web. Their biomass is often dominated by diatoms. This was the basis for the presented study into Hg accumulation in epilithic, epiphytic and planktonic diatoms, which was carried out in 2012-2013 in the coastal zone of the Puck Lagoon and the Gulf of Gdańsk (southern Baltic)...
2018: Water, Air, and Soil Pollution
https://www.readbyqxmd.com/read/29772514/the-effect-of-polymer-aging-on-the-uptake-of-fuel-aromatics-and-ethers-by-microplastics
#2
Axel Müller, Roland Becker, Ute Dorgerloh, Franz-Georg Simon, Ulrike Braun
Microplastics are increasingly entering marine, limnic and terrestrial ecosystems worldwide, where they sorb hydrophobic organic contaminants. Here, the sorption behavior of the fuel-related water contaminants benzene, toluene, ethyl benzene and xylene (BTEX) and four tertiary butyl ethers to virgin and via UV radiation aged polypropylene (PP) and polystyrene (PS) pellets was investigated. Changes in material properties due to aging were recorded using appropriate polymer characterization methods, such as differential scanning calorimetry, Fourier transform infrared spectroscopy, gel permeation chromatography, X-ray photoelectron spectroscopy, and microscopy...
May 14, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29767123/influence-of-feeding-crimped-kernel-maize-silage-on-the-course-of-subclinical-necrotic-enteritis-in-a-broiler-disease-model
#3
Nisha Sharma, Samir Ranjitkar, Nishchal K Sharma, Ricarda M Engberg
This experiment was carried out with 375 male broilers (Ross 308) from days 1 to 28 to evaluate the influence of crimped kernel maize silage (CKMS) on the manifestation of subclinical necrotic enteritis, microbiota counts, organic acid production and relative weights of gastrointestinal segments. A necrotic enteritis disease model was applied. Birds were allocated into 3 different dietary treatments: a maize-based feed (MBF, control diet), and 2 diets supplemented with 15% (CKMS15) or 30% (CKMS30) of crimped ensiled kernel maize...
December 2017: Animal nutrition
https://www.readbyqxmd.com/read/29766578/self-assembly-of-fluorescent-dehydroberberine-enhances-mitochondria-dependent-antitumor-efficacy
#4
Ruibing An, Zhanni Gu, Haifeng Sun, Yuxuan Hu, Runqi Yan, Deju Ye, Hong Liu
Selective imaging and inducing mitochondrial dysfunction in tumor cells using mitochondria-targeting probes has become as a promising approach for cancer diagnosis and therapy. Here, we report the design of a fluorescent berberine analog, dehydroberberine (DH-BBR), as a new mitochondria-targeting probe capable of self-assembling into monodisperse organic nanoparticles (DTNPs) upon integration with a lipophilic counter anion, allowing for enhanced fluorescence imaging and treatment of tumors in living mice. X-ray crystallography revealed that the self-assembly process was attributed to a synergy of different molecular interactions, including π-π stacking, O···π interaction and electrostatic interaction between DH-BBR and counter anions...
May 15, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29764335/comparative-bioaccumulation-and-effects-of-purified-and-cellular-extract-of-cylindrospermopsin-to-freshwater-fish-hoplias-malabaricus
#5
Rodrigo de Cássio da Silva, Sonia Regina Grötzner, Daniele Dietrich Moura Costa, Juan Ramón Esquivel Garcia, Juan Muelbert, Valéria Freitas de Magalhães, Francisco Filipak Neto, Ciro Alberto de Oliveira Ribeiro
Many tropical freshwater ecosystems are impacted by cyanobacteria blooms increasing the risk of cyanotoxins exposure to aquatic organisms while human populations may be exposed by eating fish, drinking water, or dermal swimming. However, few toxicological data are available on the influence of cyanobacteria blooms in particular, cylindrospermopsin (CYN) on Brazilian neotropical fish. A number of studies demonstrated the ability of CYN to bioaccumulate in freshwater organisms and consequently enter the human food chain...
May 15, 2018: Journal of Toxicology and Environmental Health. Part A
https://www.readbyqxmd.com/read/29764102/assessment-of-the-effects-of-economic-sanctions-on-iranians-right-to-health-by-using-human-rights-impact-assessment-tool-a-systematic-review
#6
Fatemeh Kokabisaghi
BACKGROUND: Over the years, economic sanctions have contributed to violation of right to health in target countries. Iran has been under comprehensive unilateral economic sanctions by groups of countries (not United Nations [UN]) in recent years. They have been intensified from 2012 because of international community's uncertainty about peaceful purpose of Iran's nuclear program and inadequacy of trust-building actions of this country. This review aimed to identify the humanitarian effects of the sanctions on the right of Iranians to health and the obligations of Iran and international community about it...
January 20, 2018: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/29762053/factors-associated-with-salmonella-prevalence-in-u-s-swine-grower-finisher-operations-2012
#7
Kathe E Bjork, Victoria Fields, Lindsey P Garber, Christine A Kopral
Nontyphoidal Salmonella is an important foodborne pathogen with diverse serotypes occurring in animal and human populations. The prevalence of the organism on swine farms has been associated with numerous risk factors, and although there are strong veterinary public health controls for preventing Salmonella from entering food, there remains interest in eradicating or controlling the organism in the preharvest environment. In this study, using data collected via the U.S. Department of Agriculture (USDA) National Animal Health Monitoring System Swine 2012 study, we describe nontyphoidal Salmonella and specific serotype prevalence on U...
May 15, 2018: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/29760287/-multi-organ-distribution-of-alpha-synuclein-pathology-in-dementia-with-lewy-bodies
#8
Koichi Wakabayashi, Yasuo Miki
In Parkinson's disease and dementia with Lewy bodies, neuronal α-synuclein aggregates (Lewy bodies and Lewy neurites) are distributed throughout the nervous system, including the brain, spinal cord, sympathetic ganglia, enteric nervous system, cardiac and pelvic plexuses, submandibular gland, adrenal medulla, and skin. Lewy bodies also occur in 10-20% of neurologically asymptomatic individuals older than 60 years. These cases are called incidental Lewy body disease (ILBD). In ILBD, Lewy bodies can be found in the brain, spinal cord, sympathetic ganglia, visceral autonomic nervous system and skin...
May 2018: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/29760207/association-of-mycobacterium-proteins-to-lipid-droplets
#9
Richard M Armstrong, Dominique C Carter, Samantha N Atkinson, Scott S Terhune, Thomas C Zahrt
Mycobacterium tuberculosis is a global pathogen of significant medical importance. A key aspect of its lifecycle is the ability to enter into an altered physiological state of non-replicating persistence during latency and resist elimination by the host immune system. One mechanism by which M. tuberculosis facilitates its survival during latency is by producing and metabolizing intracytoplasmic lipid droplets (LDs). LDs are semi-quasi organelles consisting of a neutral lipid core such as triacylglycerol surrounded by a phospholipid monolayer and proteins...
May 14, 2018: Journal of Bacteriology
https://www.readbyqxmd.com/read/29759441/nuclear-organization-mediates-cancer-compromised-genetic-and-epigenetic-control
#10
REVIEW
Sayyed K Zaidi, Andrew Fritz, Kirsten Tracy, Jonathan Gordon, Coralee Tye, Joseph Boyd, Andre Van Wijnen, Jeffrey Nickerson, Anthony Imbalzano, Jane Lian, Janet Stein, Gary Stein
Nuclear organization is functionally linked to genetic and epigenetic regulation of gene expression for biological control and is modified in cancer. Nuclear organization supports cell growth and phenotypic properties of normal and cancer cells by facilitating physiologically responsive interactions of chromosomes, genes and regulatory complexes at dynamic three-dimensional microenvironments. We will review nuclear structure/function relationships that include: 1. Epigenetic bookmarking of genes by phenotypic transcription factors to control fidelity and plasticity of gene expression as cells enter and exit mitosis; 2...
May 9, 2018: Advances in Biological Regulation
https://www.readbyqxmd.com/read/29758401/factors-determining-the-exposure-of-dairy-farmers-to-thoracic-organic-dust
#11
Hugo Pfister, Laurent Madec, Pierre Le Cann, Nathalie Costet, Martine Chouvet, Stéphane Jouneau, Laurent Vernhet
Bronchial respiratory diseases are more common in dairy farmers than in the general population, perhaps because the repeated inhalation of organic dust contributes to the development of these disorders. However, the factors determining the exposure of farmers to particles that can enter the lower bronchial tract and interact with it, i.e. the thoracic fraction of the inhalable dust, remain to be identified. We therefore measured the exposure of dairy farmers to thoracic organic dust and identified the farm features and tasks that increased exposure...
May 11, 2018: Environmental Research
https://www.readbyqxmd.com/read/29756983/-endocrine-disruptors-in-artificial-nutrition
#12
Maria B Badia Tahull, Elisabet Leiva Badosa, Montserrat Colls González, Josep Llop Talaverón
Phthalates are chemical compounds classified as endocrine disruptors which are present in practically every environment of daily life. In the field of artificial nutrition, they are relevant because they are found as plasticizers in infusion lines made with PVC. They are lipophilic molecules which weakly pair with PVC and, therefore, they are easily extracted by the fatty compounds that are part of both the parenteral and enteral nutrition, as various studies show. As endocrine disruptors, they directly affect the reproductive organs because of their antiandrogenic and estrogenic effects...
February 27, 2018: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29756542/campylobacteriosis-in-dogs-and-cats-a-review
#13
E Acke
Campylobacter species are commonly isolated from faecal samples collected from dogs and cats with the most prevalent species being C. upsaliensis, C. helveticus, and C. jejuni. Although the majority of dogs and cats are subclinically infected, some will develop mild to moderate enteritis. Immature animals, animals from intensive housing backgrounds, and animals with concurrent disease are especially predisposed to infection and the development of clinical signs. Bacterial culture methods applied in diagnostic laboratories remain biased to C...
May 13, 2018: New Zealand Veterinary Journal
https://www.readbyqxmd.com/read/29755807/assessing-the-prevalence-and-incidence-of-asthma-and-chronic-obstructive-pulmonary-disease-in-the-eastern-mediterranean-region
#14
Mohammadreza Masjedi, Elaheh Ainy, Faried Zayeri, Rogayeh Paydar
OBJECTIVES: This study conducted in 2016 aimed to assess the prevalence and incidence of asthma and chronic obstructive pulmonary disease (COPD) in the Eastern Mediterranean Region (EMR). MATERIAL AND METHODS: A meta-analysis to evaluate the published research relating to asthma and COPD was conducted using data from 23 EMR Office (EMRO) countries and searching using the web of science, PubMed, SciVerse Scopus, Google scholar, and MEDLINE databases. The keywords entered were all EMRO countries (Afghanistan, Bahrain, Djibouti, Egypt, Islamic republic Iran, Iraq, Jordan, Kuwait, Lebanon, Libyan Arab Jamahiriya, Morocco, Oman, Pakistan, Palestine, Qatar, Saudi Arab, Somalia, Sudan, Syrian Arab Republic, Tunisia, the United Arab Emirates, Yemen republic, and Cyprus) and asthma OR chronic obstructive pulmonary disease (COPD) OR (chronic bronchitis)...
April 2018: Turkish Thoracic Journal
https://www.readbyqxmd.com/read/29754816/the-cohesin-ring-uses-its-hinge-to-organize-dna-using-non-topological-as-well-as-topological-mechanisms
#15
Madhusudhan Srinivasan, Johanna C Scheinost, Naomi J Petela, Thomas G Gligoris, Maria Wissler, Sugako Ogushi, James E Collier, Menelaos Voulgaris, Alexander Kurze, Kok-Lung Chan, Bin Hu, Vincenzo Costanzo, Kim A Nasmyth
As predicted by the notion that sister chromatid cohesion is mediated by entrapment of sister DNAs inside cohesin rings, there is perfect correlation between co-entrapment of circular minichromosomes and sister chromatid cohesion. In most cells where cohesin loads without conferring cohesion, it does so by entrapment of individual DNAs. However, cohesin with a hinge domain whose positively charged lumen is neutralized loads and moves along chromatin despite failing to entrap DNAs. Thus, cohesin engages chromatin in non-topological, as well as topological, manners...
April 30, 2018: Cell
https://www.readbyqxmd.com/read/29754296/the-potential-accumulation-of-polycyclic-aromatic-hydrocarbons-in-phytoplankton-and-bivalves-in-can-gio-coastal-wetland-vietnam
#16
Hoang Thi Thanh Thuy, Tu Thi Cam Loan, Trinh Hong Phuong
Polycyclic aromatic hydrocarbons (PAHs) are one of the most important classes of anthropogenic persistent organic contaminants in the marine environment. This review discusses a whole range of findings that address various aspects of the bioaccumulation of PAHs in two common marine biota (phytoplankton and bivalves) globally and especially for Can Gio coastal wetland, Vietnam. The published information and collected data on the bioconcentration and accumulation mechanisms of PAHs as well as implications for Can Gio coastal wetland are compiled for phytoplankton and bivalves...
May 12, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29754054/toxicity-of-1-alkyl-3-methyl-imidazolium-nitrate-ionic-liquids-to-earthworms-the-effects-of-carbon-chains-of-different-lengths
#17
Yuting Shao, Jun Wang, Zhongkun Du, Bing Li, Lusheng Zhu, Jinhua Wang
Ionic liquids (ILs), which are alternatives to traditional organic solvents, have the potential to enter soil and cause negative effects on the soil micro-environment, especially soil organisms. The objective of this study was to determine the "alkyl chain effect" and "cut-off effect" mechanisms underlying the toxicity of ILs. The assessment for subchronic toxicity toward earthworms (Eisenia fetida) by five common imidazole nitrate ILs ([Cn mim]NO3 (n = 4, 6, 8, 10, and 12)) was conducted on day 28 after exposure to five concentrations (0, 5, 10, 20, and 40 mg kg-1 ) of ILs...
May 4, 2018: Chemosphere
https://www.readbyqxmd.com/read/29751329/determination-of-metals-and-pharmaceutical-compounds-released-in-hospital-wastewater-from-toluca-mexico-and-evaluation-of-their-toxic-impact
#18
Itzayana Pérez-Alvarez, Hariz Islas-Flores, Leobardo Manuel Gómez-Oliván, Damià Barceló, Miren López De Alda, Sandra Pérez Solsona, Livier Sánchez-Aceves, Nely SanJuan-Reyes, Marcela Galar-Martínez
Due to the activities inherent to medical care units, the hospital effluent released contains diverse contaminants such as tensoactives, disinfectants, metals, pharmaceutical products and chemical reagents, which are potentially toxic to the environment since they receive no treatment or are not effectively removed by such treatment before entering the drain. They are incorporated into municipal wastewater, eventually entering water bodies where they can have harmful effects on organisms and can result in ecological damage...
May 8, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29750255/investigation-of-cell-cycle-associated-structural-reorganization-in-nucleolar-fc-dfcs-from-mouse-mfc-cells-by-electron-microscopy
#19
Lingling Chen, Yang Jiao, Xin Guan, Xiliang Li, Yunpeng Feng, Mingda Jiao
Nucleolus structure alters as the cell cycle is progressing. It is established in telophase, maintained throughout the entire interphase and disassembled in metaphase. Fibrillar centers (FCs), dense fibrillar components (DFCs) and granular components (GCs) are essential nucleolar organizations where rRNA transcription and processing and ribosome assembly take place. Hitherto, little is known about the cell cycle-dependent reorganization of these structures. In this study, we followed the nucleolus structure during the cell cycle by electron microscopy (EM)...
May 1, 2018: Microscopy
https://www.readbyqxmd.com/read/29749254/uhplc-ms-ms-bioanalysis-of-human-plasma-coproporphyrins-as-potential-biomarkers-for-organic-anion-transporting-polypeptide-mediated-drug-interactions
#20
Hamza Kandoussi, Jianing Zeng, Kumar Shah, Patricia Paterson, Rasa Santockyte, Pathanjali Kadiyala, Hong Shen, Petia Shipkova, Robert Langish, Richard Burrrell, John Easter, Thomas Mariannino, Punit Marathe, Yurong Lai, Yan Zhang, Renuka Pillutla
AIM: Coproporphyrins (CP-I and CP-III) have been identified as possible biomarkers to predict human hepatic organic anion-transporting polypeptides-mediated-drug-interactions for a new drug entering clinical development. RESULTS: The method is applicable to quantify plasma CP-I and CP-III within 0.078-15.0 nM. The results identify and address a number of challenges encountered with porphyrin assays such as photodegradation and interferences. To overcome interferences from ubiquitous porphyrins, a surrogate matrix was used to prepare calibration standards...
May 11, 2018: Bioanalysis
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