keyword
MENU ▼
Read by QxMD icon Read
search

Treatment ALL in adults

keyword
https://www.readbyqxmd.com/read/29471588/attenuated-effectiveness-of-tumor-necrosis-factor-inhibitors-for-anti-human-t-lymphotropic-virus-type-1-antibody-positive-rheumatoid-arthritis
#1
Takahisa Suzuki, Shoichi Fukui, Kunihiko Umekita, Junya Miyamoto, Masataka Umeda, Ayako Nishino, Akitomo Okada, Tomohiro Koga, Shin-Ya Kawashiri, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Keita Fujikawa, Toshiyuki Aramaki, Akinari Mizokami, Naoki Matsuoka, Yukitaka Ueki, Katsumi Eguchi, Shuntaro Sato, Toshihiko Hidaka, Tomoki Origuchi, Akihiko Okayama, Atsushi Kawakami, Hideki Nakamura
OBJECTIVES: We evaluated the effectiveness of tumor necrosis factor (TNF) inhibitors for the treatment of human T-lymphotropic virus type 1 (HTLV-I)-positive rheumatoid arthritis (RA) patients in an HTLV-I endemic area. METHODS: We conducted an observational study of 585 RA patients for whom TNF inhibitors were newly introduced as a first biologic disease-modifying antirheumatic drug (bDMARD) in an HTLV-I endemic area in southwestern Japan. RESULTS: Fifty patients (8...
February 22, 2018: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29471560/knochensarkome
#2
Jendrik Hardes, Georg Gosheger, Timo Budny
Bone sarcomas are extremely rare representing approximately 0.2% among all cancer types. Due to the rarity of these tumors both the patients and the physicians can overlook or misinterpret the first often unspecific symptoms of these tumors (pain, limping and swelling). Therefore, radiographic examination (X-ray and/or MRI) of the involved region in case of inexplicable symptoms is strongly recommended. The most common primary malignant bone tumor entity is osteosarcoma, followed by chondrosarcoma and Ewing sarcoma...
February 2018: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/29471478/internet-delivered-cognitive-behavioral-therapy-for-insomnia-in-breast-cancer-survivors-a-randomized-controlled-trial
#3
Robert Zachariae, Ali Amidi, Malene F Damholdt, Cecilie D R Clausen, Jesper Dahlgaard, Holly Lord, Frances P Thorndike, Lee M Ritterband
Background: Insomnia is two to three times more prevalent in cancer survivors than in the general population, where it is estimated to be 10% to 20%. Cognitive-behavioral therapy for insomnia (CBT-I) is the recommended treatment for chronic insomnia, but meeting survivor needs remains a challenge. Internet-delivered CBT-I (iCBT-I) has been shown efficacious in otherwise healthy adults. We tested the efficacy of iCBT-I in breast cancer survivors with clinically significant sleep disturbance...
February 20, 2018: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/29471318/family-physician-awareness-of-charles-bonnet-syndrome
#4
Keith D Gordon, Tina Felfeli
Background: Charles Bonnet syndrome is characterized by formed visual hallucinations in individuals with vision loss. It is reported that one in five older adults with vision loss suffer from Charles Bonnet syndrome and the suspected lack of awareness amongst family physicians may lead to misdiagnosis and inappropriate treatment. Objective: To assess Canadian family physicians' awareness of Charles Bonnet syndrome. Methods: We conducted a national perception and practices survey of family physicians across Canada to assess (i) the level of awareness of Charles Bonnet syndrome amongst family physicians; (ii) the frequency of family physicians' encounters with patients with visual hallucinations and (iii) management strategies and referral patterns for patients with Charles Bonnet syndrome presenting to family physicians...
February 17, 2018: Family Practice
https://www.readbyqxmd.com/read/29470836/role-of-vancomycin-minimum-inhibitory-concentrations-by-modified-population-analysis-profile-method-and-clinical-outcomes-in-high-inoculum-methicillin-resistant-staphylococcus-aureus-infections
#5
Trang D Trinh, Evan J Zasowski, Kimberly C Claeys, Anthony M Casapao, Matthew Compton, Abdalhamid Lagnf, Shravya D Kidambi, Donald P Levine, Michael J Rybak
INTRODUCTION: Vancomycin remains the standard of care for invasive methicillin-resistant Staphylococcus aureus (MRSA) infections. Treatment failures from heteroresistant vancomycin-intermediate subpopulations (hVISA) are challenging to detect. Minimum inhibitory concentrations (MIC) identified by modified population analysis profile (PAP) is an alternative testing method. The aim of this study was to evaluate the role of PAP MIC on vancomycin failures in two high inoculum infections: MRSA infective endocarditis and pneumonia...
February 22, 2018: Infectious Diseases and Therapy
https://www.readbyqxmd.com/read/29470730/sacral-nerve-stimulation-versus-percutaneous-tibial-nerve-stimulation-for-faecal-incontinence-a-systematic-review-and-meta-analysis
#6
Constantinos Simillis, Nikhil Lal, Shengyang Qiu, Christos Kontovounisios, Shahnawaz Rasheed, Emile Tan, Paris P Tekkis
AIMS: Percutaneous tibial nerve stimulation (PTNS) and sacral nerve stimulation (SNS) are both second-line treatments for faecal incontinence (FI). To compare the clinical outcomes and effectiveness of SNS versus PTNS for treating FI in adults. METHOD: A literature search of MEDLINE, Embase, Science Citation Index Expanded and Cochrane was performed in order to identify studies comparing SNS and PTNS for treating FI. A risk of bias assessment was performed using The Cochrane Collaboration's risk of bias tool...
February 22, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29470573/factors-associated-with-health-related-quality-of-life-in-medically-and-surgically-treated-patients-with-glaucoma
#7
Cheryl L Khanna, David A Leske, Jonathan M Holmes
Importance: Health-related quality of life (HRQOL) is often reduced with glaucoma, but associated factors are poorly understood. Objective: To determine factors associated with reduced HRQOL in medically and surgically treated patients with glaucoma. Design, Setting, and Participants: Prospective cohort study at a tertiary referral glaucoma practice, with 160 consecutive, prospectively enrolled medically or surgically treated adult patients with glaucoma...
February 22, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29470484/the-characteristic-of-asthma-control-among-nasal-diseases-population-results-from-a-cross-sectional-study
#8
Jiangtao Lin, Jie Gao, Kefang Lai, Xin Zhou, Bei He, Jianying Zhou, Changzheng Wang
Asthma affects a large number of patients in China, but comprehensive evaluation of risks associated with poor asthma control in asthmatic patients with nasal diseases was still limited. We conducted this study to provide a comprehensive estimate of asthma control in Chinese asthma patients with combined nasal diseases, to explore the effect of kinds of nasal diseases on the asthma control, and to identify risk factors associated with uncontrolled asthmatic patients with combined nasal diseases. 1756 asthma patients concomitant with nasal diseases aged ≥17 years and representing all regions of mainland China were surveyed...
2018: PloS One
https://www.readbyqxmd.com/read/29470455/urban-rural-county-and-state-differences-in-chronic-obstructive-pulmonary-disease-united-states-2015
#9
Janet B Croft, Anne G Wheaton, Yong Liu, Fang Xu, Hua Lu, Kevin A Matthews, Timothy J Cunningham, Yan Wang, James B Holt
Chronic obstructive pulmonary disease (COPD) accounts for the majority of deaths from chronic lower respiratory diseases, the third leading cause of death in the United States in 2015 and the fourth leading cause in 2016.* Major risk factors include tobacco exposure, occupational and environmental exposures, respiratory infections, and genetics.† State variations in COPD outcomes (1) suggest that it might be more common in states with large rural areas. To assess urban-rural variations in COPD prevalence, hospitalizations, and mortality; obtain county-level estimates; and update state-level variations in COPD measures, CDC analyzed 2015 data from the Behavioral Risk Factor Surveillance System (BRFSS), Medicare hospital records, and death certificate data from the National Vital Statistics System (NVSS)...
February 23, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29470104/association-between-utilization-of-chiropractic-services-for-treatment-of-low-back-pain-and-use-of-prescription-opioids
#10
James M Whedon, Andrew W J Toler, Justin M Goehl, Louis A Kazal
OBJECTIVE: Pain relief resulting from services delivered by doctors of chiropractic may allow patients to use lower or less frequent doses of opioids, leading to reduced risk of adverse effects. The objective of this investigation was to evaluate the association between utilization of chiropractic services and the use of prescription opioid medications. DESIGN: The authors used a retrospective cohort design to analyze health insurance claims data. SETTING: The data source was the all payer claims database administered by the State of New Hampshire...
February 22, 2018: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/29469993/asthma-among-adult-patients-presenting-with-dyspnea-to-the-emergency-department-an-observational-study
#11
Win Sen Kuan, Simon Craig, Anne-Maree Kelly, Gerben Keijzers, Sharon Klim, Colin A Graham, Peter Jones, Anna Holdgate, Charles Lawoko, Said Laribi
INTRODUCTION: Shortness of breath is a common presenting symptom to the emergency department (ED) that can arise from a myriad of possible diagnoses. Asthma is one of the major causes. OBJECTIVE: To describe the demographic features, clinical characteristics, management and outcomes of adults with an emergency department (ED) diagnosis of asthma who presented to an ED in the Asia Pacific region with a principal symptom of dyspnea. METHODS: Planned sub-study of patients with an ED diagnosis of asthma identified in the Asia, Australia and New Zealand Dyspnoea in Emergency Departments (AANZDEM) study...
February 22, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29469703/a-pediatric-case-of-unusual-melanocytic-proliferation-of-the-nail
#12
Regine J Mathieu, Marjon Vatanchi, Edward R Heilman, Sharon A Glick
Pigmentation of the nail plate, or melanonychia, is typically a benign condition caused by melanocyte activation. Although rare, melanonychia may be the initial presentation of melanoma, thus all cases require an in-depth examination. Evaluation in pediatric patients can prove especially difficult as benign cases have a higher prevalence of atypia compared to adults. Lack of specific treatment guidelines in the pediatric population can make diagnosis and treatment challenging. We report a pediatric patient with melanonychia with atypical features that required significant evaluations and collaboration to ultimately reach a treatment plan...
July 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/29469632/hybrid-reconstruction-of-the-aortic-arch-using-a-double-branched-stent-graft-in-a-canine-model
#13
Fan Qiao, Cunhua Su, Qingqi Han, Mengwei Tan, Jun Wang, Yang Liu, Fanglin Lu, Lin Han, Zhiyun Xu
PURPOSE: To report the results of a hybrid approach to aortic arch repair using an innovative unibody double-branched stent graft in a canine model. MATERIALS AND METHODS: The stent-graft system consists of two parts: the main body and two branches for reconstruction of the supra-arch branches. There is a 2-cm-long suturing portion at the proximal end of the main body. Twenty adult German sheep dogs underwent a hybrid surgical treatment to place the stent-grafts into the proximal descending aorta and the supra-arch branches...
February 22, 2018: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/29469175/presence-of-autoimmune-disease-affects-not-only-risk-but-also-survival-in-patients-with-b-cell-non-hodgkin-lymphoma
#14
Geffen Kleinstern, Mor Averbuch, Rania Abu Seir, Riki Perlman, Dina Ben Yehuda, Ora Paltiel
Although autoimmune diseases (AIDs) are known to predispose to non-Hodgkin lymphoma (NHL), their association with NHL prognosis has rarely been investigated. We examined associations between autoimmunity and B-cell NHL onset by comparing AID history (determined by self-report and medication review and supplemented by chart review where possible) among 435 adult B-NHL patients in Hadassah-Hebrew University Medical Center, diagnosed 2009-2014, and 414 age-and-sex frequency-matched controls. We examined AIDs as a whole, B- and T-cell-mediated AIDs, and autoimmune thyroid diseases...
February 22, 2018: Hematological Oncology
https://www.readbyqxmd.com/read/29469072/long-term-outcome-of-diffuse-large-b-cell-lymphoma-impact-of-biosimilar-rituximab-and-radiation
#15
P Ganesan, T G Sagar, K Kannan, V Radhakrishnan, S Rajaraman, A John, S Sundersingh, V Mahajan, T S Ganesan
INTRODUCTION: Rituximab (R)-CHOP improves survival over CHOP in diffuse large B-cell lymphoma (DLBCL). The availability of biosimilar rituximab in India has increased access of this drug. We report on the impact of treatment on outcomes with special emphasis on the impact of biosimilar rituximab and radiation. METHODS: Outcomes of adults (age 15-60 years) treated with CHOP+/- Rituximab radiation were analyzed retrospectively to look at baseline features, treatment, and event-free and overall survival (EFS and OS)...
April 2017: Indian Journal of Cancer
https://www.readbyqxmd.com/read/29468808/prevalence-of-left-ventricular-hypertrabeculation-noncompaction-among-children-with-sickle-cell-disease
#16
M Louise Morrison, Corrina McMahon, Riona Tully, Noelle Enright, Ricardo Pignatelli, Jeffrey A Towbin, Colin J McMahon
OBJECTIVES: Incidence of sickle cell disease (SCD) in Ireland has dramatically increased. Disease survival has also steadily improved however cardiovascular manifestations remain important causes of morbidity. These include reports of left ventricular hypertrabeculation (LVHT)/noncompaction. We sought to investigate the prevalence of LVHT among a large cohort of children with SCD. METHODS: We retrospectively reviewed the records of all patients with a diagnosis of SCD who had undergone surveillance echocardiography at Our Lady's Children's Hospital Crumlin (OLCHC) from 1998 to 2015...
February 21, 2018: Congenital Heart Disease
https://www.readbyqxmd.com/read/29468674/mental-health-of-long-term-survivors-of-childhood-and-young-adult-cancer-a-systematic-review
#17
REVIEW
Amanda J Friend, Richard G Feltbower, Emily J Hughes, Kristian P Dye, Adam W Glaser
Childhood cancer is increasing in prevalence whilst survival rates are improving. The prevalence of adult survivors of childhood cancer is consequently increasing. Many survivors suffer long-term consequences of their cancer treatment. Whilst many of these are well documented, relatively little is known about the mental health of survivors of childhood cancer. This article aimed to describe the prevalence and spectrum of mental health problems found in adult survivors of childhood cancer using a systematic review methodology...
February 22, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29467828/age-related-differences-in-foot-mobility-in-individuals-with-patellofemoral-pain
#18
Jade M Tan, Kay M Crossley, Bill Vicenzino, Hylton B Menz, Shannon E Munteanu, Natalie J Collins
Background: Age-related changes in midfoot mobility have the potential to influence success with foot orthoses intervention in people with patellofemoral pain (PFP). The aim of this study was to determine whether older people with PFP demonstrate less foot mobility than younger adults with PFP. Methods: One hundred ninety four participants (113 (58%) women, age 32 ± 7 years, BMI 25 ± 4.9 kg/m2 ) with PFP (≥ 6 weeks duration) were included, with foot mobility quantified using reliable and valid methods...
2018: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/29467206/the-incidence-of-tuberculosis-among-adolescents-and-young-adults-a-global-estimate
#19
Kathryn J Snow, Charalambos Sismanidis, Justin Denholm, Susan M Sawyer, Stephen M Graham
Historical data show that the risk of tuberculosis increases dramatically during adolescence, and young people face unique challenges in terms of case detection and effective treatment. However, little is known about the burden of tuberculosis among young people in the modern era. This study aimed to provide the first estimates of the global and regional incidence of tuberculosis among young people aged 10-24 years.Using the World Health Organization (WHO) database of tuberculosis notifications for 2012, we estimated the burden of tuberculosis among young people by WHO region...
February 2018: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29467129/antiretroviral-treatment-long-term-alt-cohort-a-prospective-cohort-of-10-years-of-art-experienced-patients-in-uganda
#20
Barbara Castelnuovo, Frank Mubiru, Agnes N Kiragga, Rachel Musomba, Olive Mbabazi, Paul Gonza, Andrew Kambugu, Rosalind Parks Ratanshi
PURPOSE: Little information is available on patients on antiretroviral treatment (ART) after a long-term period from sub-Saharan Africa, with the longest follow-up and related outcomes being after 10 years on ART. At the Infectious Diseases Institute (IDI) (Kampala, Uganda), we set up a cohort of patients already on ART for 10 years at the time of enrolment, who will be followed up for additional 10 years. PARTICIPANTS: A prospective observational cohort of 1000 adult patients previously on ART for 10 years was enrolled between May 2014 and September 2015...
February 21, 2018: BMJ Open
keyword
keyword
116521
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"