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https://www.readbyqxmd.com/read/28743049/risk-factors-for-maternal-anaemia-and-low-birth-weight-in-pregnant-women-living-in-rural-india-a%C3%A2-prospective-cohort-study
#1
A S Ahankari, P R Myles, J V Dixit, L J Tata, A W Fogarty
OBJECTIVE: The aim of this prospective study was to estimate the prevalence and risk factors for maternal anaemia and low birth weight (LBW) in pregnant women living in Maharashtra state, India. STUDY DESIGN: This is a prospective study. METHODS: Women between 3 and 5 months of pregnancy were recruited from 34 villages based in Maharashtra state. Baseline data collection, anthropometric measurements and blood investigations were performed...
July 22, 2017: Public Health
https://www.readbyqxmd.com/read/28742379/caffeine-a-lung-drug-for-all-very-low-birth-weight-preterms
#2
Alan H Jobe
No abstract text is available yet for this article.
July 25, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28742106/epidemiology-of-enteroaggregative-escherichia-coli-infections-and-associated-outcomes-in-the-mal-ed-birth-cohort
#3
Elizabeth T Rogawski, Richard L Guerrant, Alexandre Havt, Ila F N Lima, Pedro H Q S Medeiros, Jessica C Seidman, Benjamin J J McCormick, Sudhir Babji, Dinesh Hariraju, Ladaporn Bodhidatta, Jasmin Shrestha, Japhat Anania, Athanasia Maro, Amidou Samie, Pablo Peñataro Yori, Shahida Qureshi, Mustafa Mahfuz, Pascal O Bessong, Margaret N Kosek, Tahmeed Ahmed, Zulfiqar A Bhutta, Dennis R Lang, Michael Gottlieb, Eric R Houpt, Aldo A M Lima
BACKGROUND: Enteroaggregative E. coli (EAEC) have been associated with mildly inflammatory diarrhea in outbreaks and in travelers and have been increasingly recognized as enteric pathogens in young children with and without overt diarrhea. We examined the risk factors for EAEC infections and their associations with environmental enteropathy biomarkers and growth outcomes over the first two years of life in eight low-resource settings of the MAL-ED study. METHODS: EAEC infections were detected by PCR gene probes for aatA and aaiC virulence traits in 27,094 non-diarrheal surveillance stools and 7,692 diarrheal stools from 2,092 children in the MAL-ED birth cohort...
July 24, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28739199/results-of-the-first-american-prospective-study-of-intravenous-iron-in-oral-iron-intolerant-iron-deficient-gravidas
#4
Michael Auerbach, Stephanie E James, Melissa Nicoletti, Steven Lenowitz, Nicola London, Huzefa F Bahrain, Richard Derman, Samuel Smith
BACKGROUND: Anemia affects up to 42% of gravidas. Neonatal iron deficiency is associated with low birth weight, delayed growth and development, and increased cognitive and behavioral abnormalities. While oral iron is convenient, up to 70% report significant gastrointestinal toxicity. Intravenous iron formulations allowing replacement in one visit with favorable side-effect profiles decrease rates of anemia with improved hemoglobin responses and maternal fetal outcomes. METHODS: 74 oral iron intolerant, 2(nd) and 3(rd) trimester iron deficient gravidas were questioned for oral iron intolerance and treated with intravenous iron...
July 21, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28739035/relationship-between-birth-weight-and-the-double-product-in-childhood-adolescence-and-adulthood-from-the-bogalusa-heart-study
#5
Fu Wang, Yingxiao Hua, Paul K Whelton, Tao Zhang, Camilo Alonso Fernandez, Huijie Zhang, Lydia Bazzano, Jiang He, Wei Chen, Shengxu Li
Low birth weight is associated with cardiovascular disease and its risk factors, including heart rate and blood pressure. Therefore, we examined the hypothesis that birth weight is related to blood pressure-heart rate product (double product, DP), an index of oxygen consumption and workload of the heart, at different ages. Heart rate at rest, blood pressure at rest, and birth weight data were available in 2,340 children (4 to 11 years), 1,621 adolescents (12 to 19 years), and 2,315 adults (20 to 52 years) from the Bogalusa Heart Study (total n = 6,276)...
June 28, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28738721/the-clinical-value-of-maternal-and-fetal-doppler-parameters-in-low-risk-postdates-pregnancies-%C3%A2-a-prospective-study
#6
Oshrit Lebovitz, Eran Barzilay, Shali Mazaki-Tovi, Itai Gat, Reuven Achiron, Yinon Gilboa
OBJECTIVE: To determine the clinical significance of maternal and fetal ultrasound Doppler flow indices in postdates pregnancies. METHODS: This prospective study comprised 120 low-risk pregnant women beyond 40 weeks of gestation. All participants underwent Doppler assessment including of fetal middle cerebral artery (MCA), umbilical and uterine arteries. Perinatal outcomes were recorded and evaluated for possible associations with Doppler flow values. Adverse perinatal outcomes were defined as umbilical cord arterial pH < 7...
July 24, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28738530/prenatal-low-level-phenol-exposures-and-birth-outcomes-in-china
#7
Guodong Ding, Caifeng Wang, Angela Vinturache, Shasha Zhao, Rui Pan, Wenchao Han, Limei Chen, Weiye Wang, Tao Yuan, Yu Gao, Ying Tian
Phenolic compounds are among the endocrine disruptors which are widely used in daily life products. Studies in laboratory animals showed reproductive and developmental effects. In spite of widespread exposure to phenols, only few studies examined their effects on human development. This study was designed to investigate the relationship between antenatal phenol exposure and birth outcomes in a Chinese obstetric population. Four hundred ninety-six mother-infant pairs recruited from the Laizhou Wan prospective birth cohort in northern China between 2010 and 2013 were included in the study...
July 19, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28738026/effect-of-red-blood-cell-storage-time-on-markers-of-hemolysis-and-inflammation-in-transfused-very-low-birth-weight-infants
#8
Tamara G Kalhan, David A Bateman, Rakhee M Bowker, Eldad A Hod, Sudha Kashyap
BACKGROUND: Prolonged storage of transfused red blood cells (RBCs) is associated with hemolysis in healthy adults and inflammation in animal models. We aimed to determine whether storage duration affects markers of hemolysis (e.g., serum bilirubin, iron, and non-transferrin-bound iron (NTBI)) and inflammation (e.g., interleukin (IL)-8 and monocyte chemoattractant protein (MCP)-1) in transfused very low birth weight (VLBW) infants. METHODS: Blood samples from 23 independent transfusion events were collected by heel stick before and 2-6 h after transfusion...
July 24, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28737862/neonatal-mortality-in-argentina-situation-analysis-from-2005-to-2014
#9
Juliana Z Finkelstein, Mariana Duhau, María L Fasola, Paola Escobar
INTRODUCTION: Neonatal mortality (NM) refers to deaths occurring between birth and 27 days of life. This component of infant mortality has shown the least reduction over the past 50 years. The objective of this study was to analyze the course and characteristics of NM in Argentina. POPULATION AND METHODS: This was a descriptive, ecological study of NM in Argentina conducted between 2005 and 2014 to analyze its course, causes, and the relevance of prematurity and a low birth weight...
August 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28737293/reduced-prenatal-weight-gain-and-or-augmented-postnatal-weight-gain-precedes-polycystic-ovary-syndrome-in-adolescent-girls
#10
Francis de Zegher, Thomas Reinehr, Rita Malpique, Feyza Darendeliler, Abel López-Bermejo, Lourdes Ibáñez
OBJECTIVE: Hepato-visceral fat excess is a feature of polycystic ovary syndrome (PCOS). Risk factors for such excess include low prenatal weight gain and high postnatal weight gain. This study examined whether adolescent PCOS was preceded by a relatively low birth weight and/or a relatively high BMI at diagnosis. METHODS: Study participants included 467 girls with PCOS (298 without obesity and 169 with obesity), diagnosed, respectively, in Spain and Germany; 87 healthy girls were controls...
July 24, 2017: Obesity
https://www.readbyqxmd.com/read/28737125/taxanes-in-combination-with-platinum-derivatives-for-the-treatment-of-ovarian-cancer%C3%A2-during-pregnancy-a-literature-review%C3%A2
#11
Xiaoling Zheng, Yao Zhu, Yunchun Zhao, Shisen Feng, Caihong Zheng
Ovarian cancer is one of the most common types of solid carcinoma diagnosed during pregnancy. Taxane plus a platinum derivative is a combination therapy that is predominantly used in the treatment of ovarian cancer in non-pregnant women. Pregnancy adds various complexities to a course of treatment. In pregnant patients diagnosed with cancer during the first trimester, the risks of fetal malformations and fetal loss increase following the administration of cytotoxic drugs, and this is higher with multi-agent vs...
July 24, 2017: International Journal of Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28735987/estimated-nephron-number-of-the-donor-kidney-impact-on-allograft-kidney-outcomes
#12
T Schachtner, P Reinke
BACKGROUND: Low birth weights have been associated with a reduction in nephron number with compensatory hypertrophy of existing glomeruli. The impact of donor birth weight as an estimate of nephron number on allograft function, however, has not been examined. METHODS: We collected donor birth weight, kidney weight, and volume from 91 living kidney donor-recipient pairs before nephrectomy and after 12, 36, and 60 months. Nephron number was calculated from donor birth weight and age...
July 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28735066/exclusive-breastfeeding-at-three-months-and-infant-sleep-wake-behaviors-at-two-weeks-three-and-six-months
#13
Bárbara Figueiredo, Cláudia Castro Dias, Tiago Miguel Pinto, Tiffany Field
This study assessed infant sleep-wake behavior at two weeks, three and six months as function of feeding method at three months (exclusively breastfed, partially breastfed, and exclusively formula fed infants). Mothers of 163 first-born, full-term, normal birth weight, healthy infants completed socio-demographic, depression, anxiety, and infant sleep-wake behavior measures. No effects were found for sleep arrangements, depression or anxiety, on feeding methods and sleep-wake behavior at three months. At two weeks exclusively breastfed infants at three months spent more hours sleeping and less hours awake during the 24-h period than partially breastfed infants...
July 20, 2017: Infant Behavior & Development
https://www.readbyqxmd.com/read/28734970/genetic-variation-in-low-dose-effects-of-neonatal-des-exposure-in-female-rats
#14
Hideo Ohmukai, Tsukasa Negura, Shigehiro Tachibana, Ryo Ohta
To confirm genetic variation in low-dose effects of diethylstilbestrol (DES), two inbred strains of rats, which have been selectively bred for high- and low-avoidance learning (HAA and LAA, respectively), were used in this study. LAA rats characteristically show later sexual maturation, earlier reproductive senescence, and lower body weight as compared to HAA rats. Female neonates of each strain were daily administered DES by oral gavage at doses of 0 (vehicle only), 0.05 and 0.5μg/kg for the first 5days after birth...
July 19, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/28733971/the-fetal-safety-of-enoxaparin-use-during-pregnancy-a-population-based-retrospective-cohort-study
#15
Meital Shlomo, Rafael Gorodischer, Sharon Daniel, Arnon Wiznitzer, Ilan Matok, Boris Fishman, Gideon Koren, Amalia Levy
INTRODUCTION: Enoxaparin is widely used during pregnancy as pregnancy is a hypercoagulable state; however, its fetal safety has scarcely been investigated. OBJECTIVE: Our study aimed to examine fetal safety following enoxaparin exposure during pregnancy. METHODS: A population-based, retrospective cohort study was performed by linking computerized databases, including the drug dispensing registries of Clalit Health Services in Israel and maternal and infant hospital records, between 1998 and 2009...
July 21, 2017: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/28733681/gestational-age-specific-sex-difference-in-mortality-and-morbidities-of-preterm-infants-a-nationwide-study
#16
So-Yeon Shim, Su Jin Cho, Kyoung Ae Kong, Eun Ae Park
This study aims to determine whether male sex has adverse effect on mortality and morbidities in very low birth weight infants (VLBWI) <30 weeks of gestation and to ascertain this sex effect, stratified by gestational age, adjusting for perinatal risk factors. This is a population-based study from Korean Neonatal Network for VLBWI born at 23(+0) and 29(+6) weeks of gestation between January 2013 and December 2014. The primary outcome was gestation-specific sex difference in the occurrence of mortality, combined morbidities, and individual morbidity...
July 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28733478/growth-and-morbidity-of-extremely-preterm-infants-after-early-full-enteral-nutrition
#17
Christoph Maas, Axel R Franz, Stefanie von Krogh, Jörg Arand, Christian F Poets
OBJECTIVES: To evaluate feasibility and consequences of accelerated feeding advancement on short-term outcomes in extremely low gestational age neonates (ELGANs) who stayed in our institution for >28 days. METHODS: Retrospective single-centre cohort analysis covering the years 2011-2013. Data are presented as median (IQR). RESULTS: Infants '(n=77) birth weight was 745 (640 to 960) g and gestational age at birth 26.7 (25.1 to 27.4) weeks...
July 21, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28733436/survival-by-birth-weight-and-gestational-age-in-individuals-with-congenital-heart-disease-a-population-based-study
#18
Kate E Best, Peter W G Tennant, Judith Rankin
BACKGROUND: Congenital heart disease (CHD) survival estimates are important to understand prognosis and evaluate health and social care needs. Few studies have reported CHD survival estimates according to maternal and fetal characteristics. This study aimed to identify predictors of CHD survival and report conditional survival estimates. METHODS AND RESULTS: Cases of CHD (n=5070) born during 1985-2003 and notified to the Northern Congenital Abnormality Survey (NorCAS) were matched to national mortality information in 2008...
July 21, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28731918/the-associations-of-height-for-age-weight-for-age-and-weight-for-height-with-pediatric-acute-lymphoblastic-leukemia
#19
Jeremy M Schraw, Ann T Henson, Michael E Scheurer, Michele R Forman
Height at diagnosis has been analyzed in connection with acute lymphoblastic leukemia (ALL). Most prior studies have compared cases to national reference data derived from previous birth cohorts. Our objective was to determine the association of height-for-age Z score (HAZ) at time of diagnosis with the odds ratio (OR) of ALL in a case-control study (N=498) with a contemporaneous population of age-matched, sex-matched, and ethnicity-matched controls. We hypothesized that cases would have greater mean HAZ at time of diagnosis/interview, after adjustment for weight-for-age (WAZ) and weight-for-height (WHZ)...
July 20, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28730929/development-of-a-screening-tool-to-predict-malnutrition-among-children-under-two-years-old-in-zambia
#20
Junko Hasegawa, Yoichi M Ito, Taro Yamauchi
BACKGROUND: Maternal and child undernutrition is an important issue, particularly in low- and middle-income countries. Children at high risk of malnutrition should be prioritized to receive necessary interventions to minimize such risk. Several risk factors have been proposed; however, until now, there has been no appropriate evaluation method to identify these children. In sub-Saharan Africa, children commonly receive regular check-ups from community health workers. A simple and easy nutrition assessment method is therefore needed for use by semi-professional health workers...
2017: Global Health Action
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