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https://www.readbyqxmd.com/read/29785059/early-nt-probnp-levels-as-a-screening-tool-for-the-detection-of-hemodynamically-significant-patent-ductus-arteriosus-during-the-first-week-of-life-in-very-low-birth-weight-infants
#1
Silvia Rodriguez-Blanco, Ignacio Oulego-Erroz, Sandra Gautreaux-Minaya, Alejandro Perez-Muñuzuri, Maria Luz Couce-Pico
OBJECTIVE: To assess whether early NT-ProBNP can identify the need for echocardiographic assessment of hemodynamically significant patent ductus arteriosus (HsPDA) in preterm infants. STUDY DESIGN: Prospective observational study of infants with a gestational age ≤32 weeks. Echocardiographic assessment and NT-proBNP measurement were performed at 48-96 h. ROC curves were generated to assess optimal cutoffs to detect HsPDA and predict the need for treatment. RESULTS: Eighty-five patients were included...
May 22, 2018: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29784603/does-type-of-feeding-affect-body-composition-in-very-low-birth-weight-infants-a-prospective-cohort-study
#2
Mól Nina, Zasada Magdalena, Kwinta Przemko
BACKGROUND: The aim of the study was to analyse body composition of preterm infants fed with either breast milk or formula compared to a control group of full-term newborns. METHODS: Fifty-three newborns were enrolled: a group of 34 very low birth weight (VLBW) preterm newborns subdivided into a formula-fed (n = 23; group A) and breast milk-fed (n = 11; group B) group, and a control group of 19 full-term infants (group C). Their body composition was assessed by a bioelectrical impedance analysis (BIA) either at the estimated time of birth in the VLBW group or during the 1st week of life in the full-term group...
May 4, 2018: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/29784514/breastfeeding-trends-among-very-low-birth-weight-low-birth-weight-and-normal-birth-weight-infants
#3
Angela G Campbell, Patricia Y Miranda
OBJECTIVE: To examine the change in breastfeeding behaviors over time, among low birth weight (LBW), very low birth weight (VLBW), and normal birth weight (NBW) infants using nationally representative US data. STUDY DESIGN: Univariate statistics and bivariate logistic models were examined using the Early Child Longitudinal Study-Birth Cohort (2001) and National Study of Children's Health (2007 and 2011/2012). RESULTS: Breastfeeding behaviors improved for infants of all birth weights from 2007 to 2011/2012...
May 18, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29783717/associations-of-maternal-vitamin-d-deficiency-with-pregnancy-and-neonatal-complications-in-developing-countries-a-systematic-review
#4
REVIEW
Paige van der Pligt, Jane Willcox, Ewa A Szymlek-Gay, Emily Murray, Anthony Worsley, Robin M Daly
Pregnant women in Asia, the Middle East, Africa and Latin America are at risk of vitamin D deficiency (VDD) and prevalence throughout these regions are among the highest, globally. Maternal VDD has been associated with increased risk of a number of adverse maternal and neonatal health outcomes, yet research from developing countries is limited. We assessed the associations of maternal VDD during pregnancy with adverse health outcomes by synthesizing the literature from observational studies conducted in developing countries...
May 18, 2018: Nutrients
https://www.readbyqxmd.com/read/29783163/maternal-hypothalamus-pituitary-adrenal-hpa-system-activity-and-stress-during-pregnancy-effects-on-gestational-age-and-infant-s-anthropometric-measures-at-birth
#5
Maria Gilles, Henrike Otto, Isabell A C Wolf, Barbara Scharnholz, Verena Peus, Michael Schredl, Marc W Sütterlin, Stephanie H Witt, Marcella Rietschel, Manfred Laucht, Michael Deuschle
BACKGROUND: Prenatal maternal stress might be a risk for the developing fetus and may have long-lasting effects on child and adult vulnerability to somatic and psychiatric disease. Over-exposure of the unborn to excess glucocorticoids and subsequent alteration of fetal development is hypothesized to be one of the key mechanisms linking prenatal stress with negative child outcome. METHODS: In this prospective longitudinal study, mothers-to-be (n = 405) in late pregnancy (36...
April 22, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29782436/effectiveness-of-the-neonatal-discharge-program-for-very-low-birth-weight-infants-on-parental-efficacy-and-psychological-distress
#6
Lakshmi Shandra Bos, Shefaly Shorey, Tamill Salvee Kulantaipian, Jane S P Sng, Wilson W S Tam, Serena S L Koh
This pilot study aimed to (i) evaluate the effectiveness of a neonatal discharge program, (ii) identify relationships between parent and infant factors and parental efficacy and psychological distress, and (iii) identify ways to improve the neonatal discharge program. A quasiexperimental 1-group pretest/posttest design was used. Through consecutive sampling, 42 participants were recruited. Data were collected using self-report questionnaires. Self-administering instruments gathered data on parental efficacy and psychological distress as well as feedback and recommendations on the intervention...
May 17, 2018: Journal of Perinatal & Neonatal Nursing
https://www.readbyqxmd.com/read/29779803/maternal-intake-of-milk-and-milk-proteins-is-positively-associated-with-birth-weight-a-prospective-observational-cohort-study
#7
A Mukhopadhyay, P Dwarkanath, S Bhanji, S Devi, A Thomas, A V Kurpad, T Thomas
BACKGROUND: A striking number of low birth weight (LBW) Indian babies are born annually. Previous studies have confirmed the positive association between milk intake and birth weight. However, the relations between protein and vitamin B12 from milk and birth weight have not been systematically explored. AIMS: We examined the relations between birth weight and maternal intake of milk, protein from milk and vitamin B12 from milk. METHODS: This prospective, observational cohort study was conducted in an urban South Indian hospital...
June 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29779040/association-between-unexplained-thickened-nuchal-translucency-and-adverse-pregnancy-outcomes
#8
Santee Tiyatha, Sirinart Sirilert, Ratanaporn Sekararithi, Theera Tongsong
OBJECTIVE: To determine the association between unexplained increased nuchal translucency (INT) and adverse pregnancy outcomes. PATIENTS AND METHODS: The prospective database of our fetal down screening project was accessed to retrieve the records with NT measurement and complete follow-up. Pregnancies with pre-existing medical diseases, fetal chromosomal or structural abnormalities were excluded. The selected pregnancies were classified into the INT groups (> 95th percentile), the normal (< 95th percentile) group...
May 19, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29778968/environmental-risk-factors-associated-with-low-birth-weight-the-case-study-of-the-haifa-bay-area-in-israel
#9
Alina Svechkina, Jonathan Dubnov, Boris A Portnov
BACKGROUND: Low birth weight (LBW) is known to be associated with infant mortality and postnatal health complications. Previous studies revealed strong relationships between LBW rate and several socio-demographic factors, including ethnicity, maternal age, and family income. However, studies of association between LBW rate and environmental risk factors remain infrequent. STUDY METHODS: We retrieved a geo-referenced data set, containing 7216 individual records of children born in 2015 in the Haifa Bay Area in Israel...
May 17, 2018: Environmental Research
https://www.readbyqxmd.com/read/29778493/retrograde-ureteral-catheterization-a-possible-new-treatment-for-renal-fungal-balls-in-very-low-birth-weight-infants
#10
Cheng-Wei Chen, Chyong-Hsin Hsu, Jin-Cherng Sheu, Hsin Chi, Jui-Hsing Chang, Chun-Chen Lin, Jeng-Daw Tsai
Invasive candidiasis is a serious pathogen of late-onset sepsis in very-low-birth- weight (VLBW) infants. Kidney is the most common organ involved and it causes morbidity and mortality, especially when fungal balls are formed. We report a 34-day-old female infant (28 weeks, 1152 gm) with systemic fungal infection complicated obstructive uropathy. On sonography, the fungal balls filled the entire pelvis without hydronephrosis. Percutaneous nephrostomy was not feasible. In addition to systemic antifungals, we successfully performed cystoscopy-assisted retrograde ureteral catheterization (RUC) to decompress the pelvis, which also provided a route for local amphotericin B irrigation to achieve therapeutic concentration without nephrotoxicity...
May 17, 2018: Urology
https://www.readbyqxmd.com/read/29778383/in-vitro-fertilization-interpregnancy-interval-and-risk-of-adverse-perinatal-outcomes
#11
Kristin Palmsten, Michael V Homer, Yujia Zhang, Sara Crawford, Russell S Kirby, Glenn Copeland, Christina D Chambers, Dmitry M Kissin, H Irene Su
OBJECTIVE: To compare associations between interpregnancy intervals (IPIs) and adverse perinatal outcomes in deliveries following IVF with deliveries following spontaneous conception or other (non-IVF) fertility treatments. DESIGN: Cohort using linked birth certificate and assisted reproductive technology surveillance data from Massachusetts and Michigan. SETTING: Not applicable. PATIENT(S): 1,225,718 deliveries. INTERVENTION(S): None...
May 2018: Fertility and Sterility
https://www.readbyqxmd.com/read/29777555/impact-of-nicu-oral-feeding-on-neuropsychomotor-outcomes-at-9-months-of-corrected-age-in-chinese-low-birth-weight-preterm-infants-a-retrospective-study
#12
Wenwen Ding, Lijin Zhao, Nan Sheng, Jiali Ma, Ying Zhang
AIMS AND OBJECTIVES: To examine the changes in neuropsychomotor development and investigate the effect of feeding progression in Neonatal Intensive Care Unit (NICU) on neuropsychomotor outcomes in low-birth-weight preterm infants within 9 months of corrected age. BACKGROUND: Low-birth-weight (LBW) preterm infants (<37 weeks of gestation and birth weight < 2500 g) are at a high risk for neuropsychomotor development delay. Therefore, exploring NICU practices related to neuropsychomotor development is important...
May 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29776967/multicentre-study-of-maternal-and-neonatal-outcomes-in-individuals-with-prader-willi-syndrome
#13
Preeti Singh, Ranim Mahmoud, June-Anne Gold, Jennifer L Miller, Elizabeth Roof, Roy Tamura, Elisabeth Dykens, Merlin G Butler, Dan J Driscoll, Virginia Kimonis
INTRODUCTION: Prader-Willi syndrome (PWS) is a complex genetic disorder associated with three different genetic subtypes: deletion of the paternal copy of 15q11-q13, maternal UPD for chromosome 15 and imprinting defect. Patients are typically diagnosed because of neonatal hypotonia, dysmorphism and feeding difficulties; however, data on the prenatal features of PWS are limited. OBJECTIVE: The aim of the study was to identify and compare frequencies of prenatal and neonatal clinical features of PWS among the three genetic subtypes...
May 18, 2018: Journal of Medical Genetics
https://www.readbyqxmd.com/read/29775848/long-term-outcome-in-children-with-neonatal-seizures-a-tertiary-center-experience-in-cohort-of-168-patients
#14
Biljana Vucetic Tadic, Ruzica Kravljanac, Vlada Sretenovic, Vladislav Vukomanovic
PURPOSE: The purpose of this study was to evaluate long-term outcome and assess predictors of prognosis in children with neonatal seizures (NS). METHOD: This retrospective study includes children with NS treated at our Institute from January the 1st 2005 until December the 31st 2015. The data were collected from medical charts and the electroencephalogram (EEG) database at the Institute. The predictive value was evaluated for following parameters: (1) characteristics of the patients, such as gender, gestational age, birth body weight, Apgar score, artificial ventilation; (2) etiology; (3) characteristics of seizures such as type, time of onset, resistance to treatment; and (4) EEG background activity and paroxysmal discharges...
May 15, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29775476/maternal-asthma-is-associated-with-increased-risk-of-perinatal-mortality
#15
Mari Kemppainen, Anna-Maria Lahesmaa-Korpinen, Paula Kauppi, Martti Virtanen, Suvi M Virtanen, Riitta Karikoski, Mika Gissler, Turkka Kirjavainen
BACKGROUND: Asthma is the most common chronic disease during pregnancy and it may have influence on pregnancy outcome. OBJECTIVES: Our goal was to assess the association between maternal asthma and the perinatal risks as well as possible effects of asthma medication. METHODS: The study was based on a nationwide Finnish register-based cohort between the years 1996 and 2012 in the Drug and Pregnancy Database. The register data comprised 962 405 singleton live and stillbirths, 898 333 (93...
2018: PloS One
https://www.readbyqxmd.com/read/29774394/longitudinal-health-care-cost-in-hypoplastic-left-heart-syndrome-palliation
#16
Jesse E Hansen, Nicolas L Madsen, Laurie Bishop, David L S Morales, Jeffrey B Anderson
Management of hypoplastic left heart syndrome (HLHS) is resource intensive. Heath care systems are pressured to provide value to patients by improving outcomes while decreasing costs. A single-center retrospective cohort of infants with HLHS who underwent Norwood procedure or hybrid Norwood from 2004 to 2014 and survived to first outpatient follow up were studied. The primary outcome was total cost through 12 months with a sub-analysis of patients with 60 months of data. Costs were calculated using internal cost accounting system and reported by cost center...
May 17, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29773196/reconsideration-of-the-immunotherapeutic-pediatric-safe-dose-levels-of-aluminum
#17
James Lyons-Weiler, Robert Ricketson
FDA regulations require safety testing of constituent ingredients in drugs (21 CFR 610.15). With the exception of extraneous proteins, no component safety testing is required for vaccines or vaccine schedules. The dosing of aluminum in vaccines is based on the production of antibody titers, not safety science. Here we estimate a Pediatric Dose Limit that considers body weight. We identify several serious historical missteps in past analyses of provisional safe levels of aluminum in vaccines, and provide updates relevant to infant aluminum exposure in the pediatric schedule considering pediatric body weight...
July 2018: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/29771940/unplanned-pregnancies-and-contraceptive-use-among-hiv-positive-women-in-care
#18
Madeline Y Sutton, Wen Zhou, Emma L Frazier
Among 230,360 women with diagnosed HIV in the United States (U.S.), ~ 8,500 give birth annually, and unplanned pregnancies (as with HIV-negative women) are prevalent. However, unplanned pregnancies and contraceptive use among HIV-positive women have been understudied. To examine unplanned pregnancies and contraceptive use among HIV-positive women, we used 2013-2014 data from the Medical Monitoring Project (MMP), an HIV surveillance system that produces national estimates for HIV-positive adults in care in the U...
2018: PloS One
https://www.readbyqxmd.com/read/29770761/low-birth-weight-is-associated-with-increased-fat-intake-in-school-aged-boys
#19
Adrianne R Bischoff, André K Portella, Catherine Paquet, Roberta Dalle Molle, Aida Faber, Narendra Arora, Robert D Levitan, Patrícia P Silveira, Laurette Dube
Evidence suggests that both high and low birth weight children have increased the risk for obesity and the metabolic syndrome in adulthood. Previously we have found altered feeding behaviour and food preferences in pre-school children and adults born with low birth weight. In this study, we investigated if birth weight was associated with different intake of fat, carbohydrate and/or protein at 6-12 years of age. This is a cross-sectional study where 255 guardians answered online and telephone questions including anthropometrics and demographic data, parental family food rules (food control, encouragement and restriction) and a complete web-based FFQ for their children (130 boys and 125 girls)...
June 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29769421/low-placental-visfatin-expression-is-related-to-impaired-glycaemic-control-and-fetal-macrosmia-in-pregnancies-complicated-by-type-1-diabetes
#20
R Iciek, M Brazert, E Wender-Ozegowska, M Pietryga, J Brazert
Type 1 diabetes mellitus (T1DM) is still related to altered fetal growth and severe maternal complications. We studied the possible role of placental visfatin/nicotinamide phosphoribosyltransferase (NAMPT) in fetal development in T1DM pregnancies, the possible role of placental visfatin in fetal macrosomia. Sixty five pregnant women with T1DM and singleton pregnancy were qualified into the study. Placental visfatin expression was by analysed by RT-PCR. We demonstrated the lowest expression of placental visfatin in women who delivered neonates with birth weight NBW > 4000 g (0...
February 2018: Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society
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