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CT perfusion

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https://www.readbyqxmd.com/read/29454098/quantitative-imaging-features-and-postoperative-hepatic-insufficiency-a-multi-institutional-expanded-cohort
#1
Linda M Pak, Jayasree Chakraborty, Mithat Gonen, William C Chapman, Richard Kg Do, Bas Groot Koerkamp, Kees Verhoef, Ser Yee Lee, Marco Massani, Eric P van der Stok, Amber L Simpson
BACKGROUND: Post-hepatectomy liver insufficiency (PHLI) is a significant cause of morbidity and mortality after liver resection. Quantitative imaging analysis using CT scans measures variations in pixel intensity related to perfusion. A preliminary study demonstrated a correlation between quantitative imaging features of the future liver remnant (FLR) parenchyma from preoperative CT scans and PHLI. The objective of the present study was to explore the potential application of quantitative imaging analysis in PHLI in an expanded, multi-institutional cohort...
February 14, 2018: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29449280/prediction-of-the-multisegment-clot-sign-on-dynamic-ct-angiography-of-cardioembolic-stroke
#2
Z Chen, F Shi, M Zhang, X Gong, L Lin, M Lou
BACKGROUND AND PURPOSE: The multisegment clot sign has been observed at the site of large-artery occlusion in patients with acute ischemic stroke. This study aimed to assess its occurrence rate and relationship with stroke etiologies in patients with acute intracranial large-artery occlusion. MATERIALS AND METHODS: We included consecutive patients with acute ischemic stroke who had acute intracranial large-artery occlusion and underwent perfusion CT within 8 hours after stroke onset...
February 15, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29446681/coronary-ct-angiography-use-in-patients-with-chest-pain-presenting-to-emergency-departments
#3
David C Levin, Laurence Parker, Ethan J Halpern, Vijay M Rao
OBJECTIVE: Previously published reports have shown that coronary CT angiography (CCTA) is a more efficient method of diagnosis than myocardial perfusion imaging (MPI) and stress echocardiography for patients presenting to emergency departments (EDs) with acute chest pain. In light of this evidence, the objective of this study was to examine recent trends in the use of these techniques in EDs. MATERIALS AND METHODS: The nationwide Medicare Part B databases for 2006-2015 were the data source...
February 15, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29446319/dual-energy-ct-iodine-maps-as-an-alternative-quantitative-imaging-biomarker-to-abdominal-ct-perfusion-determination-of-appropriate-trigger-delays-for-acquisition-using-bolus-tracking
#4
Stephan Skornitzke, Franziska Fritz, Philipp Mayer, Marco Koell, Jens Hansen, Gregor Pahn, Thilo Hackert, Hans-Ulrich Kauczor, Wolfram Stiller
OBJECTIVE: Quantitative evaluation of different bolus-tracking trigger delays for acquisition of dual-energy (DE) computed tomography (CT) iodine maps as an alternative to CT perfusion. METHODS: Prior to this retrospective analysis of prospectively acquired data, DECT perfusion sequences were dynamically acquired in 22 patients with pancreatic carcinoma using dual-source CT at 80/140kV p with tin filtration. After deformable motion-correction, perfusion maps of blood flow (BF) were calculated from 80kVp image series of DECT, and iodine maps were calculated for each of the 34 DECT acquisitions per patient...
February 15, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29436979/thoracoscopic-total-esophagogastrectomy-with-supercharged-colon-interposition-for-the-treatment-of-esophageal-adenocarcinoma-in-situs-inversus
#5
Alexandros Charalabopoulos, Ali Kordzadeh, Elias Sdralis, Bruno Lorenzi, Fateh Ahmad
BACKGROUND: Esophagectomy in situs inversus is challenging. With long-segment supercharged reconstruction, it becomes more perplexing and multidisciplinary surgical skills are needed. Challenges met and the surgical technique used is presented in this case report. METHODS: The case of a 49-year old patient with situs inversus abdominus and a locally advanced distal esophageal adenocarcinoma extending to the stomach is presented. RESULTS: Following neoadjuvant chemotherapy and due to inability to use the stomach as a conduit, a thoracoscopic total esophagogastrectomy with long-segment reconstruction was performed...
February 13, 2018: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/29436885/cerebral-perfusion-and-compensatory-blood-supply-in-patients-with-recent-small-subcortical-infarcts
#6
Salvatore Rudilosso, Carlos Laredo, Marco Mancosu, Nuria Moya-Planas, Yashu Zhao, Oscar Chirife, Ángel Chamorro, Xabier Urra
Hypoperfusion is the typical perfusion pattern associated with recent small subcortical infarcts of the brain, but other perfusion patterns may be present in patients with these infarcts. Using CT perfusion, we studied 67 consecutive patients who had a small subcortical infarct at a follow-up MRI study to investigate the correlation between the perfusion pattern and the clinical and radiological course. On CT perfusion map analysis, 51 patients (76%) had focal hypoperfusion, 4 patients (6%) had hyperperfusion and the remaining 12 patients (18%) showed no abnormalities...
January 1, 2018: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/29435739/multiparametric-magnetic-resonance-imaging-in-the-assessment-of-pulmonary-hypertension-initial-experience-of-a-one-stop-study
#7
Gisela M B Meyer, Fernanda B Spilimbergo, Stephan Atmayer, Gabriel S Pacini, Matheus Zanon, Guilherme Watte, Edson Marchiori, Bruno Hochhegger
INTRODUCTION: Our goal was to assess the diagnostic performance of magnetic resonance imaging (MRI) as a single method to diagnose pulmonary hypertension (PH) compared to right heart catheterization (RHC), computed tomography (CT), and ventilation/perfusion (V/Q) scintigraphy. METHODS: We identified 35 patients diagnosed with PH by RHC in our institution who have also undergone a CT, a scintigraphy, and an MRI within a month. All cases were discussed in multidisciplinary meetings...
February 12, 2018: Lung
https://www.readbyqxmd.com/read/29433968/dynamic-stress-computed-tomography-myocardial-perfusion-for-detecting-myocardial-ischemia-a-systematic-review-and-meta-analysis
#8
Minjie Lu, Shuli Wang, Arlene Sirajuddin, Andrew E Arai, Shihua Zhao
BACKGROUND: Comparing to SPECT and MRI, with higher temporal and spatial resolution and development of radiation dose reduction, myocardial computed tomography perfusion has emerged as a potential method for evaluation of hemodynamic myocardial ischemia. This meta-analysis systematically analyzed the performance of dynamic CT myocardial perfusion (DCTMP) to diagnose myocardial ischemia (MI) with clinically established reference methods [MR/SPECT/PET perfusion and fractional flow reserve (FFR)] as the reference standard...
February 10, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29433381/collateral-circulation-between-angiosomes-in-the-feet-of-diabetic-patients
#9
Erkan Orhan, Ömer Özçağlayan
Objectives The main factor in the healing of foot ulcers in diabetic patients is adequate perfusion. There is no consensus on whether direct or indirect revascularization is more effective in leg revascularization. At the centre of that debate, there is a disagreement about whether collateral circulation is sufficient or not. Our aim is to evaluate collateral circulation activity between angiosomes in the feet of diabetic patients by evaluating the level of occlusion in leg arteries and comparing the angiosome regions that have necrosis...
January 1, 2018: Vascular
https://www.readbyqxmd.com/read/29428027/does-vasopressin-exacerbate-cerebral-edema-in-patients-with-severe-traumatic-brain-injury
#10
Casey J Allen, Ty K Subhawong, Mena M Hanna, Lydia Chelala, M Ross Bullock, Carl I Schulman, Kenneth G Proctor
Arginine vasopressin (AVP) is often used as an alternative pressor to catecholamines (CATs). However, unlike CATs, AVP is a powerful antidiuretic that could promote edema. We tested the hypothesis that AVP promoted cerebral edema and/or increased requirements for osmotherapy, relative to those who received CATs, for cerebral perfusion pressure (CPP) management after traumatic brain injury (TBI). This is a retrospective review of 286 consecutive TBI patients with intracranial pressure monitoring at a single institution from September 2008 to January 2015...
January 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/29424129/micro-perfusion-and-quantitative-analysis-of-the-femoral-head-intraosseous-artery
#11
Xing Qiu, Liang-Liang Cheng, Ben-Jie Wang, Bao-Yi Liu, Lei Yang, Mingyang Yu, Guishan Gu, De-Wei Zhao
The present study investigates the feasibility of micro perfusion of femoral head specimens from femoral neck fracture patients by the inferior retinacular arteries and performing intraosseous artery quantitative analysis of the femoral head. Twelve femoral neck fracture patients who had undergone conventional hip replacement surgery were included in this study. Femoral head specimen arteries were first dissected and exposed and then perfused by the inferior retinacular arteries and all the femoral heads underwent micro-CT scanning...
February 9, 2018: Orthopaedic Surgery
https://www.readbyqxmd.com/read/29423383/biodistribution-of-99mtc-maa-on-spect-ct-performed-for-90y-radioembolization-therapy-planning-a-pictorial-review
#12
J J Bailey, Y Dewaraja, D Hubers, R Srinivasa, K A Frey
Purpose: To evaluate the frequency of 99mTc-MAA uptake in extrahepatic organs during 90Y radioembolization therapy planning. Methods: This retrospective case series of 70 subjects who underwent 99mTc-MAA hepatic artery perfusion studies between January 2014 and July 2016 for 90Y radioembolization therapy planning at our institution involved direct image review for all subjects, with endpoints recorded: lung shunt fraction, extrahepatic radiotracer uptake, time from MAA injection to imaging...
October 2017: Clinical and Translational Imaging: Reviews in Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29419477/imaging-for-pulmonary-embolism-in-sickle-cell-disease-a-17-year-experience
#13
Patrick Tivnan, Henny H Billett, Leonard M Freeman, Linda B Haramati
Sickle cell disease, a complex disorder with known pulmonary complications, has the potential to confound the diagnosis of pulmonary embolism. We hypothesized that when the choice of imaging is guided by chest radiographic results, CT pulmonary angiography (CTPA) and Ventilation-Perfusion (V/Q) scintigraphy have comparable diagnostic performance in sickle cell disease. Methods: A retrospective cohort of adults with sickle cell disease who were imaged for suspected pulmonary embolism with either CTPA or V/Q, from 2000-2016, at our institution, was established...
February 1, 2018: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29415314/a-patient-with-lower-gastrointestinal-bleeding-common-history-very-uncommon-cause-minimally-invasive-treatment
#14
Guntram Lock, Thies Daniels, Lars Kock
An 81-year-old patient with significant cardiac comorbidities, a history of sigmoid resection 6 years ago, and iliac bypass surgery 19 years ago presented with mild hematochezia for the previous 3 days. While hemodynamically stable at first, he developed massive bleeding during preparation for colonoscopy and underwent a short course of cardiopulmonary resuscitation. Colonoscopy revealed no active bleeding but a protuberance of the colonic wall and a coagulation clot. In ultrasonography immediately after endoscopy, a large aneurysm was diagnosed and diagnosis of an iliaco-colonic fistula was assumed...
February 2018: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/29414151/migrainous-aura-as-stroke-mimic-the-role-of-perfusion-computed-tomography
#15
Mariana Ridolfi, Antonio Granato, Paola Polverino, Giovanni Furlanis, Maja Ukmar, Irene Zorzenon, Paolo Manganotti
OBJECTIVES: The acute-onset of migrainuos aura (MA) can be erroneously diagnosed in Emergency Department (ED) as acute stroke (AS) and it can be classified as "stroke mimic" (SM). Perfusion computer tomography (PCT) may be useful to improve detection of infarcts. The aim of the study was to investigate the role in ED of PCT in improving diagnosis of migrainous aura. Data were compared with the well-defined perfusion patterns in patients with acute ischemic stroke. PATIENTS AND METHODS: A standardized Stroke Protocol was planned...
January 31, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29412162/diagnostic-performance-of-different-perfusion-algorithms-for-the-detection-of-angiographical-spasm
#16
Saif Afat, Carolin Brockmann, Omid Nikoubashman, Marguerite Muller, Kolja M Thierfelder, Wolfgang G Kunz, Ulrike Haberland, Marc A Brockmann, Konstantin Nikolaou, Martin Wiesmann, Ahmed E Othman
PURPOSE: To assess the diagnostic utility of different perfusion algorithms for the detection of angiographical arterial spasm. METHOD: During a 2-year period, 45 datasets from 29 patients (54.2±10,75y,20F) with suspected cerebral vasospasm after aneurysmal subarachnoid hemorrhage were included. Volume Perfusion CT (VPCT), Non-enhanced CT (NCT) and angiography were performed within 6hours post-ictus. Perfusion maps were generated using a maximum slope (MS) and a deconvolution-based approach (DC)...
February 2, 2018: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/29408832/quantitative-primary-tumor-indocyanine-green-measurements-predict-osteosarcoma-metastatic-lung-burden-in-a-mouse-model
#17
Mitchell S Fourman, Adel Mahjoub, Jon B Mandell, Shibing Yu, Jessica C Tebbets, Jared A Crasto, Peter E Alexander, Kurt R Weiss
BACKGROUND: Current preclinical osteosarcoma (OS) models largely focus on quantifying primary tumor burden. However, most fatalities from OS are caused by metastatic disease. The quantification of metastatic OS currently relies on CT, which is limited by motion artifact, requires intravenous contrast, and can be technically demanding in the preclinical setting. We describe the ability for indocyanine green (ICG) fluorescence angiography to quantify primary and metastatic OS in a previously validated orthotopic, immunocompetent mouse model...
January 17, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29402765/computed-tomography-perfusion-derived-blood-brain-barrier-permeability-does-not-yet-improve-prediction-of-hemorrhagic-transformation
#18
Alexander D Horsch, Edwin Bennink, Tom van Seeters, L Jaap Kappelle, Yolanda van der Graaf, Willem P T M Mali, Hugo W A M de Jong, Birgitta K Velthuis, Jan Willem Dankbaar
INTRODUCTION: Hemorrhagic transformation (HT) in acute ischemic stroke can occur as a result of reperfusion treatment. While withholding treatment may be warranted in patients with increased risk of HT, prediction of HT remains difficult. Nonlinear regression analysis can be used to estimate blood-brain barrier permeability (BBBP). The aim of this study was to identify a combination of clinical and imaging variables, including BBBP estimations, that can predict HT. MATERIALS AND METHODS: From the Dutch acute stroke study, 545 patients treated with intravenous recombinant tissue plasminogen activator and/or intra-arterial treatment were selected, with available admission extended computed tomography (CT) perfusion and follow-up imaging...
January 8, 2018: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/29402060/penumbral-imaging-based-thrombolysis-with-tenecteplase-is-feasible-up-to-24-hours-after-symptom-onset
#19
Mahesh Kate, Robert Wannamaker, Harsha Kamble, Parnian Riaz, Laura C Gioia, Brian Buck, Thomas Jeerakathil, Penelope Smyth, Ashfaq Shuaib, Kenneth Butcher, Derek Emery
BACKGROUND AND PURPOSE: Thrombolysis >4.5 hours after ischemic stroke onset is unproven. We assessed the feasibility of tenecteplase (TNK) treatment in patients with evidence of an ischemic penumbra 4.5 to 24 hours after onset. METHODS: Acute ischemic stroke patients underwent perfusion computed tomography (CT)/magnetic resonance imaging. Patients with cerebral blood volume (CBV) or diffusion weighted imaging Alberta Stroke Program Early CT Scores (ASPECTS) >6 and mismatch score >2 (defined as >2 ASPECTS regions with delay on mean transit time maps and normal CBV) were eligible for treatment with TNK (0...
January 2018: Journal of Stroke
https://www.readbyqxmd.com/read/29394753/-multidisciplinary-therapy-for-hepatocellular-carcinoma-with-peritoneal-dissemination
#20
Natsuko Yamauchi, Masahiro Kido, Shohei Komatsu, Motofumi Tanaka, Hisoka Kinoshita, Daisuke Tsugawa, Masafumi Awazu, Kimihiko Ueno, Hirochika Toyama, Sachio Terai, Hideyo Mukubou, Tetsuo Ajiki, Takumi Fukumoto
We report a case of bilobar multiple hepatocellular carcinoma(HCC)with peritoneal dissemination successfullytreated by dual treatment with reductive surgeryplus percutaneous isolated hepatic perfusion(PIHP). A 73-year-old man had sudden abdominal pain and was diagnosed bilobar multiple HCC through some examinations. The abdominal CT scan demonstrated onlya peritoneal dissemination under the liver. We performed partial hepatectomyof the lateral segment and the Spiegel lobe, and resected a peritoneal dissemination...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
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