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https://www.readbyqxmd.com/read/28226736/automatic-segmentation-of-lungs-in-spect-images-using-active-shape-model-trained-by-meshes-delineated-in-ct-images
#1
Cheimariotis Grigorios-Aris, Al-Mashat Mariam, Haris Kostas, Aletras H Anthony, Jogi Jonas, Bajc Marika, Maglaveras Nicolaos, Heiberg Einar, Cheimariotis Grigorios-Aris, Al-Mashat Mariam, Haris Kostas, Aletras H Anthony, Jogi Jonas, Bajc Marika, Maglaveras Nicolaos, Heiberg Einar, Bajc Marika, Al-Mashat Mariam, Jogi Jonas, Heiberg Einar, Haris Kostas, Maglaveras Nicolaos, Aletras H Anthony, Cheimariotis Grigorios-Aris
This paper presents a fully automated method for segmentation of 3D SPECT ventilation and perfusion images. It relies on statistical information on lung shape derived by CT manual segmentation and its main processing steps are: shape model extraction, binary segmentation, positioning of mean shape in SPECT images and iterative shape adaptation based on intensity profiles and on what is considered `plausible' lung shape. The Active Shape Model is used to generate accurate anatomic results in SPECT images with functional information and thus unclear borders, especially in the case of pathologies...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28219193/-analysis-of-ct-perfusion-imaging-in-chronic-cerebral-circulatory-insufficiency-and-its-relationship-with-crossed-cerebellar-diaschisis
#2
S L Liu, Y Wang, Y Zhang, H L Xu, J C Wang, W W He, X T Qin, G Q Cao, Y J Yang, Q C Zhuge, W J Chen
Objective: To investigate the change of cerebral microcirculation of chronic cerebral circulation insufficiency(CCCI) patients and the relationship between CCCI and crossed cerebellar diaschisis(CCD)by using 320-detector row of low-dose volume CT perfusion imaging. Methods: A total of 158 patients (103 males, 55 females, from 45 to 82 years old, the mean age was 62.9) with symptoms of CCCI were admitted to the First Affiliated Hospital of Wenzhou Medical University from June 2013 to January 2016. Low-dose CTP imaging of whole brain was performed to them using 320-detector row volume CT scanner...
February 7, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28218614/first-i-in-vivo-i-magnetic-particle-imaging-of-lung-perfusion-in-rats
#3
Xinyi Yedda Zhou, Kenneth Jeffris, Elaine Yu, Bo Zheng, Patrick Goodwill, Payam Nahid, Steven Conolly
Pulmonary embolism (PE), along with the closely related condition of deep vein thrombosis, affect an estimated 600,000 patients in the US per year. Untreated, PE carries a mortality rate of 30%. Because many patients experience mild or non-specific symptoms, imaging studies are necessary for definitive diagnosis of PE. Iodinated CT pulmonary angiography (CTPA) is recommended for most patients, while nuclear medicine-based ventilation/perfusion (V/Q) scans are reserved for patients in whom the use of iodine is contraindicated...
February 20, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28217316/subacute-right-heart-failure-revealing-three-simultaneous-causes-of-post-embolic-pulmonary-hypertension-in-metastatic-dissemination-of-breast-cancer
#4
Flavien Vincent, Nicolas Lamblin, Marion Classe, Guillaume Schurtz, Antoine Rauch, Marie Fertin, Pascal De Groote
A 72-year-old woman with history of breast cancer only treated surgically was referred to our department for pulmonary hypertension (PH) suspicion. Echocardiogram revealed elevated right ventricular systolic pressure. Computed tomography (CT) angiogram showed no pulmonary embolism (PE), but lung scan revealed two ventilation-perfusion mismatch areas. Right cardiac catheterization established precapillary PH. Despite treatment with PH specific therapy (sildenafil, ambrisentan, and epoprostenol), her condition worsened rapidly with acute right heart failure (RHF)...
February 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/28216521/technique-and-theory-of-hollow-fiber-phantom-for-cerebral-ct-perfusion
#5
Eiji Okaniwa, Hiroyuki Hashimoto, Kazufumi Suzuki, Hiroshi Iimura, Shingo Suzaki, Kayoko Abe, Mituhiro Ejima, Shuji Sakai
We developed a phantom using a hollow-fiber hemodialyzer to evaluate the quantitative reliability of cerebral computed tomography (CT) perfusion. Our phantom consisted of a hollow-fiber hemodialyzer and a syringe-shaped X-ray device made up of resin. The phantom can give theoretical true values for cerebral blood volume, cerebral blood flow, and mean transit time. We compared the values measured in the phantom with predicted theoretical values. The purpose of the current report is to describe the theory and experimental technique used to obtain an absolute value in a phantom...
2017: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/28209577/feasibility-of-flat-panel-detector-ct-in-perfusion-assessment-of-brain-arteriovenous-malformations-initial-clinical-experience
#6
M Garcia, T W Okell, M Gloor, M A Chappell, P Jezzard, O Bieri, J V Byrne
The different results from flat panel detector CT in various pathologies have provoked some discussion. Our aim was to assess the role of flat panel detector CT in brain arteriovenous malformations, which has not yet been assessed. Five patients with brain arteriovenous malformations were studied with flat panel detector CT, DSC-MR imaging, and vessel-encoded pseudocontinuous arterial spin-labeling. In glomerular brain arteriovenous malformations, perfusion was highest next to the brain arteriovenous malformation with decreasing values with increasing distance from the lesion...
February 16, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28205183/large-primary-pleural-synovial-sarcoma-with-severe-dyspnea-a-case-report
#7
Minoru Yamaki, Shuji Yonehara, Toshio Noriyuki
BACKGROUND: Synovial sarcoma is a malignant neoplasm of soft tissues. It occurs mainly in the extremities and is closely related to tendons, tendon sheaths, and bursal structures. Primary synovial sarcoma of the pleura and lungs is extremely rare. CASE PRESENTATION: We present the case of a 62-year-old man with a large synovial sarcoma of the left pleura. He presented with general fatigue and severe dyspnea. Chest computed tomography (CT) revealed a 20-cm tumor in the left thoracic cavity...
December 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28205113/cardiac-pet-ct-with-rb-82-optimization-of-image-acquisition-and-reconstruction-parameters
#8
P Chilra, S Gnesin, G Allenbach, M Monteiro, J O Prior, L Vieira, J A Pires Jorge
BACKGROUND: Our aim was to characterize the influence of time-of-flight (TOF) and point spread function (PSF) recovery corrections, as well as ordered subset expectation maximization (OSEM) reconstruction parameters, in (82)Rb PET/CT quantification of myocardial blood flow (MBF) and myocardial flow reserve (MFR). Rest and stress list-mode dynamic (82)Rb PET acquisition data from 10 patients without myocardial flow defects and 10 patients with myocardial blood flow defects were reconstructed retrospectively...
December 2017: EJNMMI Physics
https://www.readbyqxmd.com/read/28202246/analysis-of-myocardial-perfusion-parameters-in-an-ex-vivo-porcine-heart-model-using-third-generation-dual-source-ct
#9
Gert Jan Pelgrim, Taylor M Duguay, J Marco A Stijnen, Akos Varga-Szemes, Sjoerd Van Tuijl, U Joseph Schoepf, Matthijs Oudkerk, Rozemarijn Vliegenthart
PURPOSE: To evaluate the relationship between fractional flow reserve (FFR)-determined coronary artery stenosis severity and myocardial perfusion parameters derived from dynamic myocardial CT perfusion imaging (CTP) in an ex-vivo porcine heart model. METHODS: Six porcine hearts were perfused according to Langendorff. Circulatory parameters such as arterial blood flow (ABF) (L/min), mean arterial pressure (MAP) (mmHg) and heart rate (bpm) were monitored. Using an inflatable cuff and monitored via a pressure wire, coronary artery stenoses of different FFR grades were created (no stenosis, FFR = 0...
February 3, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28185782/acute-pulmonary-embolism-detection-with-ventilation-perfusion-spect-combined-with-full-dose-ct-what-is-the-best-option
#10
M Milà, J Bechini, A Vázquez, V Vallejos, M Tenesa, A Espinal, M Fraile, M Monreal
AIM: To compare diagnostic accuracy of Ventilation/Perfusion (V/P) single-photon emission computed tomography (SPECT) combined with simultaneous full-dose CT with a hybrid SPECT/CT scanner versus planar ventilation/perfusion (V/P) SPECT and CT angiography (CTA) in patients suspected with acute pulmonary embolism (PE). METHODS: Between 2009 and 2011, consecutive patients suspected of acute PE were referred for V/P SPECT/CT (reviewed board approved study). A contrast agent was administered to patients who had no contraindications...
February 6, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28184942/radiological-biomarkers-for-assessing-response-to-locoregional-therapies-in-hepatocellular-carcinoma-from-morphological-to-functional-imaging-review
#11
Xiao-Dan Ye, Zuguo Yuan, Jian Zhang, Zheng Yuan
Many hepatocellular carcinoma (HCC) patients do not qualify for curative surgical intervention and are instead treated with locoregional therapies (LRTs) including ablative and endovascular therapies. Assessment of imaging response is essential in the management of HCC for determining efficacy of therapy and as a surrogate marker for improved survival. The established morphological image biomarkers for tumor burden measurement continue to be applied, as size measurement can easily be used in clinical practice...
March 2017: Oncology Reports
https://www.readbyqxmd.com/read/28183285/early-detection-of-myocardial-infarction-following-blunt-chest-trauma-by-computed-tomography-a-case-report
#12
Thung-Lip Lee, Chin-Feng Hsuan, Chen-Hsiang Shih, Huai-Wen Liang, Hsing-Shan Tsai, Wei-Kung Tseng, Kwan-Lih Hsu
BACKGROUND: Blunt cardiac trauma encompasses a wide range of clinical entities, including myocardial contusion, cardiac rupture, valve avulsion, pericardial injuries, arrhythmia, and even myocardial infarction. Acute myocardial infarction due to coronary artery dissection after blunt chest trauma is rare and may be life threatening. Differential diagnosis of acute myocardial infarction from cardiac contusion at this setting is not easy. CASE PRESENTATION: Here we demonstrated a case of blunt chest trauma, with computed tomography detected myocardium enhancement defect early at emergency department...
February 10, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28182709/320-row-ct-renal-perfusion-imaging-in-patients-with-aortic-dissection-a-preliminary-study
#13
Dongting Liu, Jiayi Liu, Zhaoying Wen, Yu Li, Zhonghua Sun, Qin Xu, Zhanming Fan
OBJECTIVE: To investigate the clinical value of renal perfusion imaging in patients with aortic dissection (AD) using 320-row computed tomography (CT), and to determine the relationship between renal CT perfusion imaging and various factors of aortic dissection. METHODS: Forty-three patients with AD who underwent 320-row CT renal perfusion before operation were prospectively enrolled in this study. Diagnosis of AD was confirmed by transthoracic echocardiography...
2017: PloS One
https://www.readbyqxmd.com/read/28181172/discrepant-imaging-findings-of-portal-vein-thrombosis-with-dynamic-computed-tomography-and-computed-tomography-during-arterial-portography-in-hepatocellular-carcinoma-possible-cause-leading-to-inappropriate-treatment-selection
#14
Hidenori Toyoda, Takashi Kumada, Toshifumi Tada, Kazuyuki Mizuno, Natsuko Kobayashi, Yosuke Inukai, Akira Takeda, Yasuhiro Sone
We encountered a patient with hepatocellular carcinoma who had discrepant imaging findings on portal vein thrombosis with portal phase dynamic computed tomography (CT) and CT during arterial portography (CTAP). CTAP, via the superior mesenteric artery and via the splenic artery, both showed a portal perfusion defect in the right hepatic lobe, indicating portal vein thrombosis in the main trunk of the right portal vein. Portal phase dynamic CT clearly depicted portal perfusion of the same hepatic area. Transarterial chemoembolization was successfully performed, but it was associated with severe liver injury...
February 8, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/28177653/prognostic-value-of-stress-dynamic-myocardial-perfusion-ct-in-a-multicenter-population-with-known-or-suspected-coronary-artery-disease
#15
Felix G Meinel, Francesca Pugliese, U Joseph Schoepf, Ullrich Ebersberger, Julian L Wichmann, Gladys G Lo, Yeon Hyeon Choe, Yining Wang, Sabrina Segreto, Fabian Bamberg, Carlo N De Cecco
OBJECTIVE: The purpose of this study was to determine the prognostic value of myocardial perfusion CT for major adverse cardiac events (MACE). MATERIALS AND METHODS: Data from six centers in Asia, Europe, and North America on 144 patients with known or suspected coronary artery disease who had undergone coronary CT angiography (CCTA) and dynamic myocardial perfusion CT with a dual-source CT system were analyzed. CCTA studies were acquired at rest. Dynamic myocardial perfusion CT was performed under vasodilator stress...
February 8, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28174234/ct-perfusion-as-an-early-biomarker-of-treatment-efficacy-in-advanced-ovarian-cancer-an-acrin-and-gog-study
#16
Chaan Ng, Zheng Zhang, Susanna I Lee, Helga S Marques, Kyle Burgers, Feng Su, Joseph Bauza, Robert S Mannel, Joan Walker, Warner K Huh, Stephen C Rubin, Paul DiSilvestro, Lainie P Martin, John K Chan, Michael A Bookman, Robert L Coleman, Ting-Yim Lee
PURPOSE: ACRIN 6695 was a feasibility study investigating whether CT perfusion (CTP) biomarkers are associated with progression-free survival at 6 months (PFS-6) in patients with advanced ovarian cancer who were treated with carboplatin and either dose-dense (weekly) or conventional (3-weekly) paclitaxel, with optional bevacizumab in the prospective phase III GOG-0262 trial. EXPERIMENTAL DESIGN: ACRIN 6695 recruited participants with residual disease after primary cytoreductive surgery or planned interval cytoreduction following neoadjuvant therapy, to undergo CTP studies before (T0), 3-weeks (T1) and 4-weeks (T2) after chemotherapy initiation...
February 7, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28169856/postinterventional-critical-care-management-of-aneurysmal-subarachnoid-hemorrhage
#17
Sudhir Datar, Alejandro A Rabinstein
PURPOSE OF REVIEW: Subarachnoid hemorrhage from a ruptured aneurysm (aSAH) is a complex disorder with the potential to have devastating effects on the brain as well as other organ systems. After more than 3 decades of research, the underlying pathophysiologic mechanisms remain incompletely understood and important questions remain regarding the evaluation and management of these patients. The purpose of this review is to analyze the recent literature and improve our understanding of certain key clinical aspects...
February 4, 2017: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/28169348/the-internal-anatomy-of-titanosaur-osteoderms-from-the-upper-cretaceous-of-spain-is-compatible-with-a-role-in-oogenesis
#18
Daniel Vidal, Francisco Ortega, Francisco Gascó, Alejandro Serrano-Martínez, José Luis Sanz
Dermal armor is one of the most intriguing features of some titanosaurs, the only sauropod dinosaurs that bore osteoderms. Some studies have revealed cavities of varying sizes inside some titanosaur osteoderms, interpreted as the result of bone remodeling for mineral mobilization. Several hypotheses have been proposed to explain the need for mineral mobilization in titanosaurs. However, rejecting those hypotheses was difficult with hitherto available evidence. The Upper Cretaceous site of Lo Hueco (Cuenca; Spain) has yielded one of the largest titanosaur osteoderm sets available...
February 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28164118/multislice-analysis-of-blood-flow-values-in-ct-perfusion-studies-of-lung-cancer
#19
Silvia Malavasi, Domenico Barone, Giampaolo Gavelli, Alessandro Bevilacqua
Objectives. Tumour heterogeneity represents a key issue in CT perfusion (CTp), where all studies are usually based on global mean or median values of perfusion maps, often computed on whole tumour. We sought to determine whether, and to what extent, such global values can be representative of tumour heterogeneity, with respect to single slices, and could be used for therapy assessment. Materials and Methods. Twelve patients with one primary non-small cell lung cancer lesion were enrolled in this study, for a total amount of 26 CTp examinations and 118 slices...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28161808/does-applying-resolution-recovery-to-normal-databases-confer-an-advantage-over-conventional-3d-stereotactic-surface-projection-techniques
#20
Nobuhiro Yada, Hideo Onishi, Masahiro Miyai, Kentarou Ozasa, Takashi Katsube, Keiichi Onoda, Masuo Haramoto, Yasushi Yamamoto, Shuhei Yamaguchi, Hajime Kitagaki
We evaluated a novel normal database (NDB) generated using single photon emission computed tomography (SPECT) data obtained from healthy brains by using a SPECT/CT system, analyzed using a resolution recovery (RR) technique applied to the three-dimensional stereotactic surface projection (3D-SSP) technique. We used a three-dimensional ordered subset expectation maximization method (3D-OSEM) with applied scatter correction (SC), attenuation correction, and RR to reconstruct the data. We verified the accuracy of the novel NDB's values (Z, extent, and error scores), and compared the novel NDB to the 3D-SSP technique by using simulated misery perfusion-related patient data from a conventional NDB...
February 4, 2017: Radiological Physics and Technology
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