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https://www.readbyqxmd.com/read/27904054/epidemiology-of-dermatophytoses-in-crete-greece
#1
Sofia Maraki, Viktoria Eirini Mavromanolaki
Dermatophytoses are among the most frequently diagnosed skin infections worldwide. However, the distribution of pathogenic species and the predominating anatomical sites of infection vary with geographical location and change over time. The aim of this study was to determine the epidemiological and aetiological factors of dermatophytoses in Crete, Greece over the last 5-year period (2011-2015) and their incidence in relation to the gender and the age of the patients. We compared our findings with those previously reported from the same area and from other parts of the world...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27864837/risk-factors-for-non-purulent-leg-cellulitis-a-systematic-review-and-meta-analysis
#2
REVIEW
M Quirke, F Ayoub, A McCabe, F Boland, B Smith, R O'Sullivan, A Wakai
Non-purulent cellulitis is an acute bacterial infection of the dermal and subdermal tissues that is not associated with purulent drainage, discharge or abscess. The objective of this systematic review and meta-analysis (SRMA) was to identify and appraise all controlled observational studies that have examined risk factors for the development of non-purulent cellulitis of the leg (NPLC). A systematic literature search of electronic databases and grey literature sources was performed in July 2015. The Newcastle-Ottawa Scale (NOS) was used to assess methodological quality of included studies...
November 18, 2016: British Journal of Dermatology
https://www.readbyqxmd.com/read/27843933/onychomycosis-practical-approaches-to-minimize-relapse-and-recurrence
#3
REVIEW
Antonella Tosti, Boni E Elewski
INTRODUCTION: Toenail onychomycosis is a common disease in which treatment options are limited and treatment failures and disease recurrence are frequently encountered. It usually requires many months of treatment, and recurrence may occur in more than half of the patients within 1 year or more after the infection has been eradicated. Data on long-term treatment, follow-up and recurrence are limited. OBJECTIVE: Our objective is to interpret these data and recommend practical approaches that should minimize recurrence based on our clinical experience...
September 2016: Skin Appendage Disorders
https://www.readbyqxmd.com/read/27825175/update-on-efinaconazole-10-topical-solution-for-the-treatment-of-onychomycosis
#4
A K Gupta, C Studholme
Efinaconazole 10% nail solution is a novel topical antifungal drug for the treatment of onychomycosis. Two Phase III trials were completed using efinaconazole 10% nail solution, where 17.8% and 15.2% of patients achieved complete cure, and 55.2% and 53.4% achieved mycological cure. Several post hoc analyses were carried out using data from Phase III trials to determine the efficacy of efinaconazole with respect to disease duration, disease progression, and comorbidities of diabetes or tinea pedis with onychomycosis...
November 2016: Skin Therapy Letter
https://www.readbyqxmd.com/read/27799613/mycosis-fungoides-mimicking-tinea-pedis
#5
Steven A Hanna, Mark G Kirchhof
No abstract text is available yet for this article.
December 6, 2016: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/27667305/prevalence-and-epidemiology-of-tinea-pedis-and-toenail-onychomycosis-and-antifungal-susceptibility-of-the-causative-agents-in-patients-with-type%C3%A2-2-diabetes-in-turkey
#6
Yasemin Oz, Iman Qoraan, Ali Oz, Ilknur Balta
BACKGROUND: Diabetes patients are particularly susceptible to fungal infections because their vascular and immunological systems are compromised. OBJECTIVES: The present study aimed to determine prevalences of tinea pedis and onychomycosis, factors predisposing to their development, and antifungal susceptibilities of causative fungal species against fluconazole, itraconazole, and terbinafine in patients with type 2 diabetes mellitus (DM). METHODS: Study groups were defined according to hemoglobin A1C rates of ≥6...
September 26, 2016: International Journal of Dermatology
https://www.readbyqxmd.com/read/27666873/enhancement-of-the-topical-tolnaftate-delivery-for-the-treatment-of-tinea-pedis-via-provesicular-gel-systems
#7
Mona Mahmoud AbouSamra, Alaa Hamed Salama
Tolnaftate is a thiocarbamate antifungal drug which is therapeutically active against dermatophytes that cause various forms of tinea. Due to the small amount of tolnaftate released from ordinary ointment bases and insufficient penetration through the infected skin layers the need to incorporate the drug in a more suitable pharmaceutical form has evolved. A provesicular system is one such form that can solve these problems. Once in contact with the skin, dilution with moisture occurs and the provesicular system rapidly transforms into a vesicular one...
October 19, 2016: Journal of Liposome Research
https://www.readbyqxmd.com/read/27648034/tinea-pedis-and-onychomycosis-frequency-in-diabetes-mellitus-patients-and-diabetic-foot-ulcers-a-cross-sectional-observational-study
#8
Gamze Akkus, Mehtap Evran, Dilek Gungor, Mehmet Karakas, Murat Sert, Tamer Tetiker
OBJECTIVE: Impaired cellular immunity and reduced phagocytic function of polymorphonuclear leukocytes facilitate the development of skin fungal and bacterial infections due to uncontrolled hyperglycemia in diabetic patients. In our study, we aimed to assess onychomycosis and/or tinea pedis frequency in diabetic patients, and effects on the development of chronic complications, particularly foot ulcer. METHODS: We included 227 diabetic patients in the study. Forty-three patients had diabetic foot ulcer...
July 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27602974/econazole-nitrate-foam-1-improves-the-itch-of-tinea-pedis
#9
Alan B Fleischer, Isabelle Raymond
Econazole nitrate topical foam, 1%, is indicated for the treatment of interdigital tinea pedis caused by <em>Trichophyton rubrum, Trichophyton mentagrophytes,</em> and <em>Epidermophyton floccosum</em> in patients 12 years of age and older. The symptom of itch or pruritus was evaluated in two randomized, double-blind, parallel-group, vehicle-controlled, multicenter Phase III studies in which econazole foam was compared with foam vehicle in subjects with interdigital tinea pedis. A thin, uniform layer of study treatment was applied once daily to all clinically affected interdigital regions of both feet for four weeks...
September 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/27537822/tinea-and-onychomycosis
#10
Theodore Rosen
Onychomycosis and tinea pedis are common fungal infections affecting the nails and feet, respectively. Two newly approved topical agents for onychomycosis are efinaconazole and tavaborole, both of which have demonstrated respectable cure rates in clinical studies. For tinea pedis, naftifine 2% and luliconazole 1% are new agents, both administered for relatively short courses, that may foster greater adherence Semin Cutan Med Surg 35(supp6):S110-S113.
June 2016: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/27520535/epidemiological-trends-of-dermatophytosis-in-tehran-iran-a-five-year-retrospective-study
#11
S Zamani, G Sadeghi, F Yazdinia, H Moosa, A Pazooki, Z Ghafarinia, M Abbasi, M Shams-Ghahfarokhi, M Razzaghi-Abyaneh
OBJECTIVE: Dermatophytosis is the most frequent fungal infection all over the world and its frequency is constantly increasing. The aim of this study was to evaluate clinical features and epidemiological trends of dermatophytosis over the years 2010 to 2014 in Tehran, Iran. PATIENTS AND METHODS: A total of 13,312 patients clinically suspected of cutaneous fungal infections were examined. Skin scales, plucked hairs, nail clippings and sub-ungual debris were examined by direct microscopy and culture...
August 9, 2016: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/27502503/new-antifungal-agents-and-new-formulations-against-dermatophytes
#12
Aditya K Gupta, Kelly A Foley, Sarah G Versteeg
A variety of oral and topical antifungal agents are available for the treatment of superficial fungal infections caused by dermatophytes. This review builds on the antifungal therapy update published in this journal for the first special issue on Dermatophytosis (Gupta and Cooper 2008;166:353-67). Since 2008, there have not been additions to the oral antifungal armamentarium, with terbinafine, itraconazole, and fluconazole still in widespread use, albeit for generally more severe or recalcitrant infections...
August 8, 2016: Mycopathologia
https://www.readbyqxmd.com/read/27496524/characterization-of-clinically-important-dermatophytes-in-north-of-iran-using-pcr-rflp-on-its-region
#13
M Didehdar, T Shokohi, B Khansarinejad, S Ali Asghar Sefidgar, M Abastabar, I Haghani, N Amirrajab, M Mondanizadeh
OBJECTIVE: Dermatophytosis is considered as one of the major public health problems in the world. Accurate identification of the dermatophytes species is important for recognition of the environment and animal sources of infection. In this survey, 1500 clinical specimens taken from outpatients suspected of dermatophytosis and they were examined by direct microscopy and culture. MATERIALS AND METHODS: In total, three hundred and twelve dermatophytes were isolates recovered in culture, they were identified using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method based on the ribosomal DNA internal transcribed spacer (ITS) regions...
August 2, 2016: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/27488125/tavaborole-efinaconazole-and-luliconazole-three-new-antimycotic-agents-for-the-treatment-of-dermatophytic-fungi
#14
Jacqueline Saunders, Kayla Maki, Renee Koski, S Eric Nybo
Fungal diseases of the nail bed (onychomycosis) and epidermis are recurrent illnesses in the elderly and immunocompromised patients, which have few efficacious treatment options. Current treatment options for onychomycosis are limited to topical agents, laser treatment, and oral antifungals. Previous generations of topical agents were not efficacious, owing to poor penetration of the nail bed. Oral antifungal drugs, such as itraconazole, terbinafine, and fluconazole, not only give better response rates but also inhibit a host of CYP450 enzymes...
August 3, 2016: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/27435974/increased-risk-of-tinea-pedis-and-onychomycosis-among-swimming-pool-employees-in-netanya-area-israel
#15
Avner Shemer, Aditya K Gupta, Boaz Amichai, Sharon Baum, Aviv Barzilai, Renata Farhi, Yehonathan Kaplan, Melissa A MacLeod
Tinea pedis and onychomycosis often co-occur in individuals. A relationship between swimming pools and tinea pedis exists; however, little research has investigated the relationship between onychomycosis, tinea pedis, and swimming pools. This study sought to examine the prevalence of tinea pedis and onychomycosis among swimming pool employees, a population that may be at risk of tinea infections. Samples were taken from 169 employees at 21 swimming pools in the Netanya area, Israel. KOH microscopy and culture was used to identify fungi...
July 19, 2016: Mycopathologia
https://www.readbyqxmd.com/read/27429269/antifungal-effect-of-non-woven-textiles-containing-polyhexamethylene-biguanide-with-sophorolipid-a-potential-method-for-tinea-pedis-prevention
#16
Hiromi Sanada, Gojiro Nakagami, Kimie Takehara, Taichi Goto, Nanase Ishii, Satoshi Yoshida, Mizuyuki Ryu, Yuichiro Tsunemi
Tinea pedis is a preventable skin disease common in elderly or diabetic patients. Daily foot washing is effective for prevention, but can be difficult for many patients. Additionally, conventional methods cannot eliminate fungi within the stratum corneum, a common site for fungal invasion. This study investigates the antifungal effects, cytotoxicity, permeability, and efficacy of non-woven textiles containing polyhexamethylene biguanide (PHMB) mixed with sophorolipid. Permeability of PHMB with varying concentrations of sophorolipid was assessed via a cultured skin model...
2014: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/27425231/skin-diseases-of-the-hands-and-feet
#17
D M Elston, W F Bergfeld
In brief A variety of dermatologic problems affect the hands and feet of active patients, often producing significant pain and disability. Traumatic disorders include friction blisters, calcaneal petechiae, subungual hemorrhage, and plezogenic papules. Infectious disorders include hot tub folliculitis, swimming pool granuloma, tinea pedis, warts, and herpetic whitlow. Athletic shoe dermatitis is a common allergic disorder, and hand eczema is a common disorder with a strong hereditary component. Prompt diagnosis and treatment can minimize morbidity...
March 1994: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/27407482/clinico-mycological-profile-of-superficial-mycosis-in-a-hospital-in-north-east-india
#18
Sanjiv Grover, P Roy
A clinico-mycological study of superficial mycoses was conducted on 121 cases (98 males and 23 females). Direct microscopy by KOH mount and culture was undertaken to isolate the fungal pathogen in each case. The commonest age group involved was 21-30 years (39.6%). Dermatophytosis was the commonest clinical presentation (70.5%), followed by candidiasis (20.5%) and Pityriasis versicolor (9.0%). The commonest dermatophytosis was Tinea pedis (29.2%), followed by T cruris (26.2%). The commonest dermatophyte isolated was Trichophyton tonsurans (20...
April 2003: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/27385109/-sports-associated-dermatophytoses-an-overview
#19
REVIEW
P Mayser, W Handrick, P Nenoff
Because of high exposure (e. g. swimmers and athletes competing on mats) and disposition (e. g. microtraumata of the skin in runners) athletes are prone to a higher risk for mycotic infections by dermatophytes. In disciplines with close contact during competition-especially wrestlers and judoists-infections by the anthropophilic Trichophyton (T.) tonsurans are most important (tinea gladiatorum). These infections are highly contagious and often cause small epidemics especially if the primary source of infection is not promptly recognized...
September 2016: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/27309978/oxygenated-monoterpenes-rich-volatile-oils-as-potential-antifungal-agents-for-dermatophytes
#20
N Dias, M C Dias, C Cavaleiro, M C Sousa, N Lima, M Machado
Essential oils (EOs) extracted from Lavandula luisieri and Cymbopogon citratus were tested for their antifungal activity against ten clinical isolates of dermatophytes isolated from cases of tinea pedis. Inhibition of conidial germination and antifungal drug/EO combination assay were tested on two ATCC reference strains of Trichophyton rubrum and Trichophyton mentagrophytes. EOs were characterised by high amount of oxygenated monoterpenes in their composition. Strong antifungal activity was observed for the majority of clinical strains, and fungicidal activity was demonstrated...
June 16, 2016: Natural Product Research
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