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Å Lodenius, J Piehl, A Östlund, J Ullman, M Jonsson Fagerlund
Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) can prolong apnoea time in adults. Therefore, THRIVE used for pre-oxygenation in rapid sequence induction of anaesthesia could extend safe apnoea time during prolonged laryngoscopy and intubation. In this randomised controlled trial, we compared the lowest peripheral oxygen saturation (SpO2 ) during intubation when pre-oxygenating with either traditional facemask or THRIVE. Eighty adult patients, undergoing rapid sequence induction of anaesthesia for emergency surgery, were randomly allocated to pre-oxygenation with 100% oxygen with facemask or with THRIVE...
January 13, 2018: Anaesthesia
G H Mills
Postoperative pulmonary complications are a major determinant of outcome for patients and consume huge resources within hospital, particularly in critical care. Prediction and anticipation of postoperative pulmonary complications are vital for patient selection and, in some cases, for informed patient consent. Being able to assess the likelihood of postoperative pulmonary complications also allows research into methods to reduce them by allowing allocation of patients to the appropriate arms of research trials...
January 2018: Anaesthesia
Kena Liu, Pingjiang Ge, Xiaoli Sheng, Jie Jiang, Huabiao Qin
OBJECTIVES: We describe a survival nonstimulated in vivo canine phonation model using distending laryngoscope, cramp frame, and constant humidified glottal airflow to elicit phonation. METHODS: Five beagle dogs were involved in this study. One cuffed endotracheal tube was placed below the glottis through the tracheotomy and delivered humidified airflow to the glottis. Arytenoids approximation was maintained using a clamp under the distending laryngoscope. Acoustic and aerodynamic parameters were measured using synchronous signal collection system and analysis software...
January 1, 2018: Annals of Otology, Rhinology, and Laryngology
Hong-Bin Luo, Mei Wang, Jin Zhang, Zheng-Fang Tian, Yang Zou, Xiaoming Ren
Proton conducting materials have attracted increasing interest because of the promising technological applications as key components in various electrochemical devices. It is of great significance for technique application to seek for superior proton conducting materials, operating under both anhydrous and humidified conditions in a wide temperature range. Herein we demonstrate the proton conductance of an open-framework chalcogenide, (CH3NH3)2Ag4Sn3S8 (1) and the postsynthesis product 2 achieved by doping hydrochloric acid into 1...
December 29, 2017: ACS Applied Materials & Interfaces
I de la Fuente-Sancho, Ó Romeu-Bordas, I Fernández-Aedo, G Vallejo De la Hoz, S Ballesteros-Peña
AIM: To determine the risk of microbiological contamination with hospital use high- and low-flow bubbling humidifiers. METHODS: A systematic literature review was carried out in 6 databases. Observational or experimental studies published between 1990 and 2016 were selected, written in English or Spanish, and in which microbiological contamination with hospital use high- and low-flow bubbling humidifiers was investigated. RESULTS: A total of 12 articles were included: 4 analyzed the water from reusable humidifiers, 4 analyzed the water from prefilled system humidifiers, and the rest compared samples from both models...
December 16, 2017: Medicina Intensiva
Ruby Schnirman, Nasifa Nur, Alice Bonitati, Gerardo Carino
A 67-year-old woman with morbid obesity and severe obstructive sleep apnea presented to the emergency department with 2 days of productive cough, fever, shortness of breath and loose stools. A chest x-ray showed extensive bilateral infiltrates, and she was quickly intubated for acute hypoxic respiratory failure. A urine legionella antigen test was positive, and she was admitted to the intensive care unit with a diagnosis of severe legionella pneumonia. She improved over the next week with a course of levofloxacin...
2017: SAGE Open Medical Case Reports
Sooyong Park, Seok-Hwa Yoon, Ann Misun Youn, Seung Hyun Song, Ja Gyung Hwang
Background: Intraoperative hypothermia is common in patients undergoing general anesthesia during arthroscopic hip surgery. In the present study, we assessed the effect of heating and humidifying the airway with a heated wire humidification circuit (HHC) to attenuate the decrease of core temperature and prevent hypothermia in patients undergoing arthroscopic hip surgery under general anesthesia. Methods: Fifty-six patients scheduled for arthroscopic hip surgery were randomly assigned to either a control group using a breathing circuit connected with a heat and moisture exchanger (HME) (n = 28) or an HHC group using a heated wire humidification circuit (n = 28)...
December 2017: Korean Journal of Anesthesiology
Tahereh Pornamazeh, Zahra Yadegari, Amir Ghasemi, Seyedeh Mahsa Sheykh-Al-Eslamian, Shiva Shojaeian
Introduction: The present study sought to evaluate and compare biocompatibility and setting time of Retro mineral trioxide aggregate (MTA), calcium-enriched mixture (CEM) and Angelus MTA. Methods and Materials: CEM cement, Angelus MTA and Retro MTA were assessed in set and fresh states. Extracts transformed to each cavity of three 24-well plates in which 1×104 cell were seeded into each well 24 h earlier. All specimens were incubated in a humidified incubator with 5% CO2 at 37°C...
2017: Iranian Endodontic Journal
A Macann, F Fauzi, J Simpson, G Sasso, H Krawitz, C Fraser-Browne, J Manitz, A Raith
PURPOSE/OBJECTIVE(S): To model in a subset of patients from TROG 07.03 managed at a single site the association between domiciliary based humidification use and mucositis symptom burden during radiotherapy (RT) for head and neck cancer (HNC) when factoring in volumetric radiotherapy parameters derived from tumour and normal tissue regions of interest. MATERIALS/METHODS: From June 2008 through June 2011, 210 patients with HNC receiving RT were randomised to either a control arm or humidification using the Fisher & Paykel Healthcare MR880 humidifier...
December 2017: Oral Oncology
Kazuma Niinomi, Satoru Miyazawa, Mitsuhiro Hibino, Noritaka Mizuno, Sayaka Uchida
Keggin-type polyoxometalate (POM)-based compounds have long been considered as one of the environmentally friendly candidates of solid electrolytes exhibiting high proton conductivity under high relative humidity (RH >95%). However, their application has been limited by the lack of structural stability and large decrease in conductivity with a slight decrease in RH. In order to overcome these disadvantages, we report a series of crystalline composites based on Preyssler-type POMs ([Na(H2O)P5W30O110]14-, [Bi(H2O)P5W30O110]12-), which are known to show higher acidity in comparison to Keggin-type POMs, and polymers (polyethylene glycol (PEG), polyallylamine (PAA))...
December 7, 2017: Inorganic Chemistry
S Carpinteri, S Sampurno, J Malaterre, R Millen, M Dean, J Kong, T Chittleborough, A Heriot, A C Lynch, R G Ramsay
BACKGROUND: The aim of this study was to monitor the effect of humidified-warm carbon dioxide (HWCO2 ) delivered into the open abdomen of mice, simulating laparotomy. METHODS: Mice were anaesthetized, ventilated and subjected to an abdominal incision followed by wound retraction. In the experimental group, a diffuser device was used to deliver HWCO2 ; the control group was exposed to passive air flow. In each group of mice, surgical damage was produced on one side of the peritoneal wall...
November 28, 2017: British Journal of Surgery
Abel Pérez-González, F Sara Ceccarelli, Bruno G O Monte, Daniel N Proud, Márcio Bernardino DaSilva, Maria E Bichuette
A new troglobitic harvestman, Relictopiolus galadriel gen. nov et sp. nov., is described from Olhos d'Água cave, Itacarambi, Minas Gerais State, Brazil. Morphological characters, including male genitalia and exomorphology, suggest that this species belongs to the family Kimulidae, and it appears to share the greatest similarities with Tegipiolus pachypus. Bayesian inference analyses of a molecular dataset strongly support the inclusion of this species in Kimulidae and confirm the hypothesized sister-group relationship between R...
2017: PloS One
Jean K Marshall, Noel Tait, Jan van der Linden
INTRODUCTION: Avoiding tissue desiccation is a common recommendation to reduce postoperative complications following open abdominal surgery, although difficult to achieve delicately without damaging the peritoneal mesothelium. Insufflation of humidified-warm CO2 into the abdomen during open abdominal surgery is proposed as an invisible, effortless way to prevent desiccation. We hypothesized that desiccation during open abdominal surgery would cause loss of peritoneal mesothelium that would be prevented by insufflation of humidified-warm CO2...
December 2017: Journal of Surgical Research
Waldemar A Carlo, Robert L Chatburn
No abstract text is available yet for this article.
November 23, 2017: Journal of Pediatrics
Imran Khan, M M R Chowdhury, Seok-Hwan Song, Ayman Mesalam, Shimin Zhang, Atif Ali Khan Khalil, Eun-Hee Jung, Ju-Boong Kim, Laila Jafri, Bushra Mirza, Il-Keun Kong
Lupeol is a triterpene with various pharmacological properties. This study investigated the effect of lupeol on the in vitro development of bovine embryos. Oocytes (270 per group, 1620 in total) obtained from slaughterhouse-derived ovaries were matured and fertilized in vitro and then cultured for 8 days in a humidified atmosphere of 5% CO2 in air at 38.5 °C. The in vitro maturation medium was supplemented with 0.5, 1.0, 2.0, 3.0, and 4.0 μM lupeol. Treatment with 2.0 μM lupeol significantly (P < 0...
November 13, 2017: Theriogenology
Roberta Corona, Maria Mercedes Binda, Leila Adamyan, Victor Gomel, Philippe R Koninckx
Background: Microsurgical tenets and peritoneal conditioning during laparoscopic surgery (LS) decrease postoperative adhesions and pain. For a trial in human, the strong beneficial effects of N2O needed to be confirmed in open surgery (OS). Results: In a mouse model for OS, the effect of the gas environment upon adhesions was evaluated. Experiment I evaluated desiccation and the duration of exposure to CO2, N2O or CO2 + 4%O2. Experiment II evaluated the dose-response curve of adding N2O to CO2...
2017: Gynecological Surgery
Neil R MacIntyre
No abstract text is available yet for this article.
December 2017: Critical Care Medicine
Dong-Uk Park, Seung-Hun Ryu, Hyun-Suk Roh, Eun Lee, Hyun-Ju Cho, Jisun Yoon, So-Yeon Lee, Young Ah Cho, Kyung-Hyun Do, Soo-Jong Hong
BACKGROUND: Children aged ≤6years reportedly account for 52% of victims of humidifier disinfectant-associated lung injuries. OBJECTIVES: To evaluate the association of humidifier disinfectants with lung injury risk among children aged ≤6years. METHODS: Patients with humidifier disinfectant-associated lung injuries (n=214) who were clinically evaluated to have a definite (n=108), probable (n=49), or possible (n=57) association with humidifier disinfectants as well as control patients (n=123) with lung injury deemed unlikely to be associated with humidifier disinfectant use were evaluated to determine factors associated with increased risk of humidifier disinfectant-associated lung injury using unconditional multiple logistic regression analysis...
November 7, 2017: Science of the Total Environment
Kaveh Baghaei, Seyed Mohmoud Hashemi, Samaneh Tokhanbigli, Ali Asadi Rad, Hamid Assadzadeh-Aghdaei, Abdolhamid Sharifian, Mohammad Reza Zali
Aim: We describe the minimum requirements and a simplified method for isolation and characterization of mesenchymal stem cells (MSCs) from human bone marrow. Background: MSCs are well known adult stem cells present in many tissues such as adipocytes, chondrocytes, osteoblasts, and neurons. Many isolations and characterization methods have emerged to apply MSCs in the clinical applications, which many of them are expensive and time-consuming. Methods: MSC isolation was carried out from human bone marrow, and cultured in defined medium...
2017: Gastroenterology and Hepatology From Bed to Bench
Jae Sun Kim
This research focuses on the analysis regarding disclosure of financial conflicts of interest (FCOI) after Gelsinger v. University of Pennsylvania (Penn). The main legal issue was that the participants did not have enough opportunity to make an autonomous decision about participating in the research because he was not informed about the researchers' and the institution's substantial FCOI. The disclosure system was adopted by the Code of Federal Regulations. Under the regulation, researchers and institutions need to report FCOI over $5,000 to the institution, and the internal review boards have to report to the federal authority if needed...
December 2017: Journal of Korean Medical Science
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