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https://www.readbyqxmd.com/read/28108095/indoor-temperature-and-humidity-in-new-york-city-apartments-during-winter
#1
Ashlinn Quinn, Jeffrey Shaman
BACKGROUND: Concerns about indoor residential humidity have largely centered on dampness prevention. Overly dry air, however, may favor the survival of some viruses and hence respiratory infections. Many residents employ portable humidifiers to humidify their home environment, yet the effect of these humidifiers on indoor humidity is not known. METHODS: We monitored indoor temperature and humidity in 34 apartments in New York City during winter 2014-2015. We combined information from the monitors with surveyed information on building, household, and apartment-level factors and with information on household humidifier use...
January 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28100527/transnasal-humidified-rapid-insufflation-ventilatory-exchange-thrive-in-children-a-randomized-controlled-trial
#2
S Humphreys, P Lee-Archer, G Reyne, D Long, T Williams, A Schibler
BACKGROUND: Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) was introduced to adult anaesthesia to improve the safety of airway management during apnoea before intubation. The objective of our study was to determine whether THRIVE safely prolongs apnoeic oxygenation in children. METHODS: This was a randomized controlled trial in 48 healthy children, with normal airways and cardiorespiratory function, in age groups 0-6 and 7-24 months, 2-5 and 6-10 yr old, presenting for elective surgery or imaging under general anaesthesia...
February 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28100516/transnasal-humidified-rapid-insufflation-ventilatory-exchange-thrive-in-children-a-step-forward-in-apnoeic-oxygenation-paradigm-shift-in-ventilation-or-both
#3
EDITORIAL
N Jagannathan, N Burjek
No abstract text is available yet for this article.
February 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28099321/preoxygenation-physiologic-basis-benefits-and-potential-risks
#4
Usharani Nimmagadda, M Ramez Salem, George J Crystal
Preoxygenation before anesthetic induction and tracheal intubation is a widely accepted maneuver, designed to increase the body oxygen stores and thereby delay the onset of arterial hemoglobin desaturation during apnea. Because difficulties with ventilation and intubation are unpredictable, the need for preoxygenation is desirable in all patients. During emergence from anesthesia, residual effects of anesthetics and inadequate reversal of neuromuscular blockade can lead to hypoventilation, hypoxemia, and loss of airway patency...
February 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28093047/3d-cell-printing-of-large-volume-tissues-application-to-ear-regeneration
#5
Jung-Seob Lee, Byung Soo Kim, Dong Hwan Seo, Jeong Hun Park, Dong-Woo Cho
The three-dimensional (3D) printing of large-volume cells, printed in a clinically relevant size, is one of the most important challenges in the field of tissue engineering. However, few studies have reported the fabrication of large-volume cell-printed constructs (LCCs). To create LCCs, appropriate fabrication conditions should be established: factors involved include fabrication time, residence time, and temperature control of the cell-laden hydrogel in the syringe to ensure high cell viability and functionality...
January 17, 2017: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/28078247/effects-of-biebersteinia-multifida-hydro-ethanol-extract-on-proliferation-and-apoptosis-of-human-prostate-cancer-and-human-embryonic-kidney-cells
#6
Alireza Golshan, Samira Hassanzadeh, Maryam Mojdekanloo, Zahra Tayarani-Najaran
OBJECTIVE: Biebersteinia (Geraniaceae) has a history of use in traditional medicine in some countries including Iran. In the present study, cytotoxic and apoptogenic properties of hydro-ethanol extract of B. multifidi was investigated on human prostate cancer cell lines (PC3 and DU 145) and human embryonic kidney 293 (HEK293) cells. MATERIALS AND METHODS: Cells were cultured in RPMI-1640 medium supplemented with 10% FBS at 37ºC in a humidified atmosphere of 95% air and 5% CO2...
November 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/28054235/heated-humidified-high-flow-nasal-cannula-for-prevention-of-extubation-failure-in-preterm-infants
#7
Sasivimon Soonsawad, Buranee Swatesutipun, Anchalee Limrungsikul, Pracha Nuntnarumit
OBJECTIVES: To compare extubation failure rate between the heated humidified high-flow nasal cannula (HHHFNC) and continuous positive airway pressure (CPAP) groups. METHODS: Intubated infants with gestational age (GA) <32 wk, who were ready to extubate, were randomized to receive respiratory support with either CPAP or HHHFNC after extubation. In CPAP group, nasal mask CPAP with preset pressure and fraction of inspired oxygen (FiO2) equal to positive end-expiratory pressure (PEEP) and FiO2 of ventilator before extubation was applied...
January 5, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28046522/su-c-204-05-magnetic-resonance-induced-adaptive-response-to-orthovoltage-radiation-therapy-in-fsa-and-sa-nh-mouse-tumor-cell-lines
#8
K Mendel, R Miller, J Murley, M Sadinski, D Grdina
PURPOSE: To assess the effect of pre-treatment Magnetic Resonance Imaging (MRI) on cell survival following orthovoltage radiation therapy. METHODS: This in vitro study examined the survival of FSa cells (extracted from methylcholanthrene-induced fibrosarcoma in the flank of a C3H female mouse) and SA-NH cells (derived from a spontaneously arising murine sarcoma tumor) having undergone an MRI scan prior to radiation exposure. Cell cultures were kept at 37 C, in a humidified environment with 5% CO2, and were grown to confluence prior to the start of the experiment...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28043780/influence-of-mouth-opening-on-oropharyngeal-humidification-and-temperature-in-a-bench-model-of-neonatal-continuous-positive-airway-pressure
#9
Hendrik S Fischer, Tim L Ullrich, Christoph Bührer, Christoph Czernik, Gerd Schmalisch
Clinical studies show that non-invasive respiratory support by continuous positive airway pressure (CPAP) affects gas conditioning in the upper airways, especially in the presence of mouth leaks. Using a new bench model of neonatal CPAP, we investigated the influence of mouth opening on oropharyngeal temperature and humidity. The model features the insertion of a heated humidifier between an active model lung and an oropharyngeal head model to simulate the recurrent expiration of heated, humidified air. During unsupported breathing, physiological temperature and humidity were attained inside the model oropharynx, and mouth opening had no significant effect on oropharyngeal temperature and humidity...
December 30, 2016: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28035669/a-randomised-controlled-trial-comparing-transnasal-humidified-rapid-insufflation-ventilatory-exchange-thrive-pre-oxygenation-with-facemask-pre-oxygenation-in-patients-undergoing-rapid-sequence-induction-of-anaesthesia
#10
F Mir, A Patel, R Iqbal, M Cecconi, S A R Nouraei
Pre-oxygenation is an essential part of rapid sequence induction of general anaesthesia for emergency surgery, in order to increase the oxygen reservoir in the lungs. We performed a randomised controlled trial of transnasal humidified rapid insufflation ventilatory exchange (THRIVE) pre-oxygenation or facemask pre-oxygenation in patients undergoing emergency surgery. Twenty patients were allocated to each group. No patient developed arterial oxygen saturation < 90% during attempted tracheal intubation. Arterial blood gases were sampled from an arterial catheter immediately after intubation...
December 30, 2016: Anaesthesia
https://www.readbyqxmd.com/read/28035467/erratum-to-warmed-and-humidified-carbon-dioxide-for-abdominal-laparoscopic-surgery-meta-analysis-of-the-current-literature
#11
David Balayssac, Bruno Pereira, Jean-Etienne Bazin, Bertrand Le Roy, Denis Pezet, Johan Gagnière
No abstract text is available yet for this article.
December 29, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/28012990/assessment-of-skin-barrier-function-and-biochemical-changes-of-ex-vivo-human-skin-in-response-to-physical-and-chemical-barrier-disruption
#12
Nadine Döge, Araks Avetisyan, Sabrina Hadam, Eva Katharina Barbosa Pfannes, Fiorenza Rancan, Ulrike Blume-Peytavi, Annika Vogt
Topical dermatotherapy is intended to be used on diseased skin. Novel drug delivery systems even address differences between intact and diseased skin underlining the need for pre-clinical assessment of different states of barrier disruption. Herein, we studied how short-term incubation in culture media compared to incubation in humidified chambers affects human skin barrier function and viability. On both models we assessed different types and intensities of physical and chemical barrier disruption methods with regard to structural integrity, biophysical parameters and cytokine-levels...
December 21, 2016: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/28011792/high-flow-nasal-cannula-versus-ncpap-duration-to-full-oral-feeds-in-preterm-infants-a-randomised-controlled-trial
#13
Sinead J Glackin, Anne O'Sullivan, Sherly George, Jana Semberova, Jan Miletin
OBJECTIVE: To compare the time taken by preterm infants with evolving chronic lung disease to achieve full oral feeding when supported with humidified high flow nasal cannula (HFNC) or nasal continuous positive airway pressure (NCPAP). DESIGN: Single centre randomised controlled trial. SETTING: Level III neonatal intensive care unit at the Coombe Women and Infants University Hospital, Dublin, Ireland. PATIENTS: Very low birthweight (birth weight <1500 g) infants born before 30 weeks' gestation who were NCPAP-dependent at 32 weeks corrected gestational age were eligible to participate...
December 23, 2016: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28003690/all-india-difficult-airway-association-2016-guidelines-for-the-management-of-unanticipated-difficult-tracheal-intubation-in-adults
#14
Sheila Nainan Myatra, Amit Shah, Pankaj Kundra, Apeksh Patwa, Venkateswaran Ramkumar, Jigeeshu Vasishtha Divatia, Ubaradka S Raveendra, Sumalatha Radhakrishna Shetty, Syed Moied Ahmed, Jeson Rajan Doctor, Dilip K Pawar, Singaravelu Ramesh, Sabyasachi Das, Rakesh Garg
The All India Difficult Airway Association (AIDAA) guidelines for management of the unanticipated difficult airway in adults provide a structured, stepwise approach to manage unanticipated difficulty during tracheal intubation in adults. They have been developed based on the available evidence; wherever robust evidence was lacking, or to suit the needs and situation in India, recommendations were arrived at by consensus opinion of airway experts, incorporating the responses to a questionnaire sent to members of the AIDAA and the Indian Society of Anaesthesiologists...
December 2016: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/27989595/analysis-of-genomic-responses-in-a-rat-lung-model-treated-with-a-humidifier-sterilizer-containing-polyhexamethyleneguanidine-phosphate
#15
Min-Seok Kim, Seok Won Jeong, Seong-Jin Choi, Jin-Young Han, Sung-Hwan Kim, Seokjoo Yoon, Jung-Hwa Oh, Kyuhong Lee
The antimicrobial biocide polyhexamethyleneguanidine (PHMG) phosphate is the main ingredient in the commercially available humidifier disinfectant. PHMG phosphate-based humidifier disinfectants can cause pulmonary fibrosis and induce inflammatory and fibrotic responses both in vivo and in vitro. However, toxicological mechanisms including genomic alterations induced by inhalation exposure to PHMG phosphate have not been elucidated. Therefore, this study evaluated the toxicological effects of the PHMG phosphate-containing humidifier disinfectant...
December 15, 2016: Toxicology Letters
https://www.readbyqxmd.com/read/27977876/introducing-high-flow-nasal-cannula-to-the-neonatal-transport-environment
#16
Michael A Boyle, Arunava Dhar, Rajiv Chaudhary, Susan Kent, Samantha S O'Hare, Theodore Dassios, Susan Broster
Respiratory support using heated humidified high-flow nasal cannula (HFNC) therapy has become established practice over the past decade in neonatal intensive care units. HFNC therapy is delivered through small thin tapered cannulae that sit at the nasal aperture using oxygen, or blended oxygen and air, at flow rates greater than 1L/min(1, 2). Recently several studies have demonstrated that it can be safely used as a mode of respiratory support and that the positive end expiratory pressure generated is comparable to that delivered using continuous positive airway pressure (CPAP) (3-5)...
December 15, 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27976517/warmed-humidified-co2-insufflation-benefits-intraoperative-core-temperature-during-laparoscopic-surgery-a-meta-analysis
#17
Meara Dean, Robert Ramsay, Alexander Heriot, John Mackay, Richard Hiscock, A Craig Lynch
BACKGROUND: Intraoperative hypothermia is linked to postoperative adverse events. The use of warmed, humidified CO2 to establish pneumoperitoneum during laparoscopy has been associated with reduced incidence of intraoperative hypothermia. However, the small number and variable quality of published studies have caused uncertainty about the potential benefit of this therapy. This meta-analysis was conducted to specifically evaluate the effects of warmed, humidified CO2 during laparoscopy...
December 14, 2016: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/27935333/cost-utility-analysis-of-the-insufflation-of-warmed-humidified-carbon-dioxide-during-open-and-laparoscopic-colorectal-surgery
#18
Michelle Jenks, Matthew Taylor, Judith Shore
BACKGROUND: An evaluation was conducted to estimate the cost-effectiveness of insufflation of warmed humidified CO2 during open and laparoscopic colorectal surgery compared with usual care from a UK NHS perspective. METHODS: Decision analytic models were developed for open and laparoscopic surgery. Incremental costs per quality-adjusted life year (QALY) were estimated. The open surgery model used data on the incidence of intra-operative hypothermia and applied risks of complications for hypothermia and normothermia...
December 26, 2016: Expert Review of Pharmacoeconomics & Outcomes Research
https://www.readbyqxmd.com/read/27930709/assessing-inhalation-exposures-associated-with-contamination-events-in-water-distribution-systems
#19
Michael J Davis, Robert Janke, Thomas N Taxon
When a water distribution system (WDS) is contaminated, short-term inhalation exposures to airborne contaminants could occur as the result of domestic water use. The most important domestic sources of such exposures are likely to be showering and the use of aerosol-producing humidifiers, i.e., ultrasonic and impeller (cool-mist) units. A framework is presented for assessing the potential effects of short-term, system-wide inhalation exposures that could result from such activities during a contamination event...
2016: PloS One
https://www.readbyqxmd.com/read/27923269/what-must-be-done-to-prevent-another-humidifier-disinfectant-disaster
#20
Jong-Hyeon Lee
The humidifier disinfectant disaster (HDD) was not a simple poisoning accident by biocides, but a singular disaster in history created by chemicals in household products. This disaster was a result of the failure of a system for the management of chemical and product safety. Since the management authority for chemical usage safety is different from those for chemical safety in products, many blind areas for chemical safety management in products still remain. The 'Act on the Registration and Evaluation, etc...
2016: Environmental Health and Toxicology
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