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https://www.readbyqxmd.com/read/28934352/global-reaction-to-the-recent-outbreaks-of-zika-virus-insights-from-a-big-data-analysis
#1
Nicola Luigi Bragazzi, Cristiano Alicino, Cecilia Trucchi, Chiara Paganino, Ilaria Barberis, Mariano Martini, Laura Sticchi, Eugen Trinka, Francesco Brigo, Filippo Ansaldi, Giancarlo Icardi, Andrea Orsi
OBJECTIVE: The recent spreading of Zika virus represents an emerging global health threat. As such, it is attracting public interest worldwide, generating a great amount of related Internet searches and social media interactions. The aim of this research was to understand Zika-related digital behavior throughout the epidemic spreading and to assess its consistence with real-world epidemiological data, using a behavioral informatics and analytics approach. METHODS: In this study, the global web-interest and reaction to the recently occurred outbreaks of the Zika Virus were analyzed in terms of tweets and Google Trends (GT), Google News, YouTube, and Wikipedia search queries...
2017: PloS One
https://www.readbyqxmd.com/read/28930054/impact-of-substance-messages-in-music-videos-on-youth-beware-the-influence-of-connectedness-and-its-potential-prevention-shielding-effect
#2
Cristel Antonia Russell, Véronique Régnier-Denois, Boris Chapoton, Denise Buhrau
OBJECTIVE: Two studies were conducted to investigate the role of connectedness with music videos in affecting youths' beliefs about substances (alcohol and tobacco) embedded therein and the potential for a prevention message to limit the impact of these images. METHOD: The first study used cross-sectional data from a national sample of 1,023 adolescents (54.3% male) to evaluate the relationship between youths' consumption of music videos and their beliefs about the consequences of consuming alcohol and tobacco...
September 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/28929717/-thunderstorm-and-asthma-outbreaks-during-pollen-season
#3
Maria D'Amato, Isabella Annesi-Maesano, Antonio Molino, Mauro Mormile, Carolina Vitale, Alessandro Vatrella, Alessandro Sanduzzi, Gennaro D'Amato
An increasing body of evidence shows the occurrence of asthma epidemics, sometimes also severe, during thunderstorms in the pollen season in various geographical zones. The main hypothesis explaining association between thunderstorms and asthma claims that thunderstorms can concentrate pollen grains at ground level; these grains may then release allergenic particles of respirable size in the atmosphere after their rupture by osmotic shock. During the first 20-30 minutes of a thunderstorm, patients suffering from pollen allergy may inhale a high concentration of the allergenic material dispersed into the atmosphere, which can, in turn, induce asthmatic reactions, often severe...
May 2017: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/28929103/authorization-and-toxicity-of-veterinary-drugs-and-plant-protection-products-residues-of-the-active-ingredients-in-food-and-feed-and-toxicity-problems-related-to-adjuvants
#4
REVIEW
Szandra Klátyik, Péter Bohus, Béla Darvas, András Székács
Chemical substances applied in animal husbandry or veterinary medicine and in crop protection represent substantial environmental loads, and their residues occur in food and feed products. Product approval is governed differently in these two sectors in the European Union (EU), and the occurrence of veterinary drug (VD) and pesticide residues indicated by contamination notification cases in the Rapid Alert System for Food and Feed of the EU also show characteristic differences. While the initial high numbers of VD residues reported in 2002 were successfully suppressed to less than 100 cases annually by 2006 and on, the number of notification cases for pesticide residues showed a gradual increase from a low (approximately 50 cases annually) initial level until 2005 to more than 250 cases annually after 2009, with a halt occurring only in 2016...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28928926/a-unique-complication-of-self-expandable-metal-stent-placement-in-malignant-duodenal-obstruction
#5
Christopher J Down, Lalit Kumar, Sukhpal Singh, Darmarajah Veeramootoo
Intestinal obstruction is a common complication in patients with advanced gastrointestinal malignancies. In the last two decades, endoscopic placement of duodenal stents has become a mainstay of palliative treatment in patients with unresectable obstructive duodenal pathology. Self-expandable metal stents have been reported to have excellent success rates, besides dramatically improve the patient's quality of life by reinstating the oral feeding ability. Re-intervention rates remain high, commonly as a consequence of tumour ingrowth resulting stent occlusion...
September 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28924143/fructooligosaccharide-fos-and-galactooligosaccharide-gos-increase-bifidobacterium-but-reduce-butyrate-producing-bacteria-with-adverse-glycemic-metabolism-in-healthy-young-population
#6
Feitong Liu, Pan Li, Muxuan Chen, Yuemei Luo, M Prabhakar, Huimin Zheng, Yan He, Qi Qi, Haoyu Long, Yi Zhang, Huafang Sheng, Hongwei Zhou
The gut microbiota has been implicated in glucose intolerance and its progression towards type-2 diabetes mellitus (T2DM). Relevant randomized clinical trial with prebiotic intervention was inadequate. We sought to evaluate the impact of fructooligosaccharides (FOS) and galactooligosaccharides (GOS) on glycemia during oral glucose tolerance test (OGTT) and intestinal microbiota. A randomized double-blind cross-over study was performed with 35 adults treated with FOS and GOS for 14 days (16 g/day). Faeces sampling, OGTT and anthropometric parameters were performed...
September 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28917947/effect-of-meal-glycemic-load-and-caffeine-consumption-on-prolonged-monotonous-driving-performance
#7
Christopher Bragg, Ben Desbrow, Susan Hall, Christopher Irwin
OBJECTIVE: Monotonous driving involves low levels of stimulation and high levels of repetition and is essentially an exercise in sustained attention and vigilance. The aim of this study was to determine the effects of consuming a high or low glycemic load meal on prolonged monotonous driving performance. The effect of consuming caffeine with a high glycemic load meal was also examined. METHOD: Ten healthy, non-diabetic participants (7 males, age 51±7yrs, mean±SD) completed a repeated measures investigation involving 3 experimental trials...
September 14, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28914144/impaired-disengagement-of-attention-and-its-relationship-to-emotional-distress-in-infants-at-high-risk-for-autism-spectrum-disorder
#8
Susan Bryson, Nancy Garon, Tracey McMullen, Jessica Brian, Lonnie Zwaigenbaum, Vickie Armstrong, Wendy Roberts, Isabel Smith, Peter Szatmari
INTRODUCTION: We provide data on visual orienting and emotional distress in infants at high and low risk for autism spectrum disorder (ASD). METHOD: Participants included 83 high-risk (HR) infants with an older sibling with ASD and 53 low-risk (LR) control infants with no family history of ASD. Infants were assessed on the gap-overlap task and a parent-completed temperament questionnaire at 6 and 12 months of age. At 36 months of age, an independent, gold standard diagnostic assessment for ASD was conducted...
September 15, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28912821/thyrotoxicosis-and-choledocholithiasis-masquerading-as-thyroid-storm
#9
Christian L Horn, Patricia A Short
A 26-year-old female, thirteen months postpartum, presented to the emergency department for four weeks of epigastric abdominal pain, pruritus, new onset jaundice, and 11.3 kgs (25 lbs) unintentional weight loss. On examination, she was afebrile, tachycardic, alert, and oriented and had jaundice with scleral icterus. Labs were significant for undetectable TSH, FT4 that was too high to measure, and elevated total bilirubin, direct bilirubin, alkaline phosphatase, and transaminases. Abdominal ultrasound revealed cholelithiasis without biliary ductal dilation...
2017: Case Reports in Medicine
https://www.readbyqxmd.com/read/28905873/cardiovascular-effects-of-marijuana-and-synthetic-cannabinoids-the-good-the-bad-and-the-ugly
#10
REVIEW
Pal Pacher, Sabine Steffens, György Haskó, Thomas H Schindler, George Kunos
Dysregulation of the endogenous lipid mediators endocannabinoids and their G-protein-coupled cannabinoid receptors 1 and 2 (CB1R and CB2R) has been implicated in a variety of cardiovascular pathologies. Activation of CB1R facilitates the development of cardiometabolic disease, whereas activation of CB2R (expressed primarily in immune cells) exerts anti-inflammatory effects. The psychoactive constituent of marijuana, Δ(9)-tetrahydrocannabinol (THC), is an agonist of both CB1R and CB2R, and exerts its psychoactive and adverse cardiovascular effects through the activation of CB1R in the central nervous and cardiovascular systems...
September 14, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28903932/nhs-is-warned-to-be-on-high-alert-for-flu-this-winter
#11
Jacqui Wise
No abstract text is available yet for this article.
September 13, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28895007/analysis-of-trace-metal-concentrations-in-raw-cow-s-milk-from-three-dairy-farms-in-north-gondar-ethiopia-chemometric-approach
#12
M L Akele, D Z Abebe, A K Alemu, A G Assefa, A Madhusudhan, R R de Oliveira
Concentrations of essential (Cu, Mn, and Zn) and toxic (Cr, Cd, and Pb) trace metals in 30 raw cow's milk samples were quantified using flame atomic absorption spectrometry. The samples were collected from the Nara-Awudarda, Tana-Abo, and Kosoye Amba-Rass sites in North Gondar, Ethiopia, preserved in a deep freezer (-20 °C), and then digested by Kjeldahl apparatus with HNO3/H2O2 (5:2; v/v) at 300 °C for 2.5 h. The data were subject to principal component analysis (PCA) and partial least square-discriminant analysis (PLS-DA)...
September 11, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28890382/in-vitro-genotoxicity-and-in-vivo-subchronic-evaluation-of-the-anti-inflammatory-pyrazole-compound-lqfm021
#13
Soraia Santa de Moura, Renato Ivan de Ávila, Lara Barroso Brito, Rhaul de Oliveira, Gisele Augusto Rodrigues de Oliveira, Francine Pazini, Ricardo Menegatti, Aline Carvalho Batista, Cesar Koppe Grisolia, Marize Campos Valadares
Scientific evidences have highlighted 5-(1-(3-fluorophenyl)-1H-pyrazol-4-yl)-2H-tetrazole (LQFM021) as a promising anti-inflammatory, analgesic and antinociceptive agent due to its effects on peripheral opioid receptors associated with activation of the nitric oxide/cGMP/KATP pathway. Despite these important pharmacological findings, toxicity data of LQFM021 are scarce. Thus, this study investigated the in vitro genotoxicity of LQFM021 through cytokinesis-block micronucleus assay (OECD Nº 487/2014). Moreover, zebrafish model was used to assess the embryotoxicity potential of LQFM021 using fish embryo toxicity test (OECD Nº 236/2013) with extended exposure to evaluate subchronic larval development...
September 7, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/28886141/the-impact-of-vehicle-moving-violations-and-freeway-traffic-flow-on-crash-risk-an-application-of-plugin-development-for-microsimulation
#14
Junhua Wang, Yumeng Kong, Ting Fu, Joshua Stipancic
This paper presents the use of the Aimsun microsimulation program to simulate vehicle violating behaviors and observe their impact on road traffic crash risk. Plugins for violations of speeding, slow driving, and abrupt stopping were developed using Aimsun's API and SDK module. A safety analysis plugin for investigating probability of rear-end collisions was developed, and a method for analyzing collision risk is proposed. A Fuzzy C-mean Clustering algorithm was developed to identify high risk states in different road segments over time...
2017: PloS One
https://www.readbyqxmd.com/read/28877969/overdominant-effect-of-a-chrna4-polymorphism-on-cingulo-opercular-network-activity-and-cognitive-control
#15
Sepideh Sadaghiani, Bernard Ng, Andre Altmann, Jean-Baptiste Poline, Tobias Banaschewski, Arun L W Bokde, Uli Bromberg, Christian Büchel, Erin Burke Quinlan, Patricia Conrod, Sylvane Desrivières, Herta Flor, Vincent Frouin, Hugh Garavan, Penny Gowland, Jürgen Gallinat, Andreas Heinz, Bernd Ittermann, Jean-Luc Martinot, Marie-Laure Paillère Martinot, Hervé Lemaitre, Frauke Nees, Dimitri Papadopoulos Orfanos, Tomáš Paus, Luise Poustka, Sabina Millenet, Juliane H Fröhner, Michael N Smolka, Henrik Walter, Robert Whelan, Gunter Schumann, Valerio Napolioni, Michael Greicius
The nicotinic system plays an important role in cognitive control, and is implicated in several neuropsychiatric conditions. Yet, the contributions of genetic variability in this system to individuals' cognitive control abilities are poorly understood, and the brain processes that mediate such genetic contributions remain largely unidentified. In this first large-scale neuroimaging genetics study of the human nicotinic receptor system (two cohorts, males and females, fMRI total N=1586, behavioral total N=3650), we investigated a common polymorphism of the high-affinity nicotinic receptor α4β2 (rs1044396 on the CHRNA4 gene) previously implicated in behavioral and nicotine-related studies (albeit with inconsistent major/minor allele impacts)...
September 6, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28876455/the-age-friendly-health-system-imperative
#16
Terry Fulmer, Kedar S Mate, Amy Berman
The unprecedented changes happening in the American healthcare system have many on high alert as they try to anticipate legislative actions. Significant efforts to move from volume to value, along with changing incentives and alternative payment models, will affect practice and the health system budget. In tandem, growth in the population aged 65 and older is celebratory and daunting. The John A. Hartford Foundation is partnering with the Institute for Healthcare Improvement to envision an age-friendly health system of the future...
September 6, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28875054/current-status-of-electronic-medical-record-systems-in-hospitals-and-clinics-in-korea
#17
Young-Taek Park, Dongwoon Han
OBJECTIVES: Many healthcare organizations and professionals have had interests in healthcare information and communication technology (ICT). The objective of this study was to investigate the current status of overall healthcare ICT, especially focusing on Electronic Medical Record (EMR) systems in Korea. METHODS: This study used a part of the nationwide survey collected for the OECD benchmarking ICT study. The Health Insurance Review and Assessment Service conducted the survey from November 19, 2013 to January 10, 2014...
July 2017: Healthcare Informatics Research
https://www.readbyqxmd.com/read/28873426/dna-in-a-bottle-rapid-metabarcoding-survey-for-early-alerts-of-invasive-species-in-ports
#18
Yaisel J Borrell, Laura Miralles, Hoang Do Huu, Khaled Mohammed-Geba, Eva Garcia-Vazquez
Biota monitoring in ports is increasingly needed for biosecurity reasons and safeguarding marine biodiversity from biological invasion. Present and future international biosecurity directives can be accomplished only if the biota acquired by maritime traffic in ports is controlled. Methodologies for biota inventory are diverse and now rely principally on extensive and labor-intensive sampling along with taxonomic identification by experts. In this study, we employed an extremely simplified environmental DNA (eDNA) sampling methodology from only three 1-L bottles of water per port, followed by metabarcoding (high-throughput sequencing and DNA-based species identification) using 18S rDNA and Cytochrome oxidase I as genetic barcodes...
2017: PloS One
https://www.readbyqxmd.com/read/28872282/changes-in-bacterial-flora-and-antibiotic-resistance-in-clinical-samples-isolated-from-patients-hospitalized-in-the-military-institute-of-medicine-in-warsaw-poland-between-2005-2012
#19
Aneta Guzek, Zbigniew Rybicki, Dariusz Tomaszewski
BACKGROUND: Hospital infections have become an important problem. Knowledge of microbiological situations both helps in ensuring that the optimal choice of antibacterial treatment is made, and in improving the results of the selected therapy. OBJECTIVE: In this paper, both the changes in the bacterial flora of patients hospitalized in the Military Institute of Medicine, and the bacterial resistance to antimicrobials were analyzed. MATERIAL AND METHODS: Data were collected between 2005 and 2012...
2017: Przegla̧d Epidemiologiczny
https://www.readbyqxmd.com/read/28871712/some-quantitative-eeg-features-in-default-mode-resting-state-network-under-general-anaesthesia
#20
Peter Jombík, Michal Drobny, Beata Saniova, Martin Fischer, Petra Kaderjaková, Marianna Lajčiaková, Erika Bakosova, Eva Drobna, Petr Bob, Vladimír Nosáľ
OBJECTIVES: The default mode resting state network (DMRSN) constitutes a circuit which is active in conditions when the subject is at rest. We tested the hypothesis that its function will be altered during unconsciousness. METHODS: Changes in the mean squared coherences in five conventional frequency bands (delta to gamma) in DMRSN during general anaesthesia (GA) were investigated in 39 patients. They were compared with the normal EEG of 86 alert subjects, severely abnormal EEG of 112 patients with dementia and/or encephalopathy, and the mathematical model of brain death...
August 5, 2017: Neuro Endocrinology Letters
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