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https://www.readbyqxmd.com/read/28090397/insights-about-fall-prevention-of-older-adults-in-the-state-of-hawai-i
#1
Yuka Yamazaki, Cullen T Hayashida, Valerie Yontz
The senior population in Hawai'i is growing at a dramatic pace. In the older population, falls and fall-related injuries are leading causes of morbidity and mortality. Moreover, the health care costs for falls are very high. The State of Hawai'i has taken measures to prevent falls through the promotion of medication reviews, vision checks, home assessments, and exercise. However, current published examinations of fall preventive measures have been insufficient, and more research is needed to confirm risk factors, effectiveness of preventive measures, and to explore future objectives...
January 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/28077345/tips-and-traps-lessons-from-codesigning-a-clinician-e-monitoring-tool-for-computerized-cognitive-behavioral-therapy
#2
Frederick Sundram, Susan J Hawken, Karolina Stasiak, Mathijs Fg Lucassen, Theresa Fleming, Matthew Shepherd, Andrea Greenwood, Raechel Osborne, Sally N Merry
BACKGROUND: Computerized cognitive behavioral therapy (cCBT) is an acceptable and promising treatment modality for adolescents with mild-to-moderate depression. Many cCBT programs are standalone packages with no way for clinicians to monitor progress or outcomes. We sought to develop an electronic monitoring (e-monitoring) tool in consultation with clinicians and adolescents to allow clinicians to monitor mood, risk, and treatment adherence of adolescents completing a cCBT program called SPARX (Smart, Positive, Active, Realistic, X-factor thoughts)...
January 11, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/28073441/applied-simulations-and-integrated-modelling-for-the-understanding-of-toxic-and-harmful-algal-blooms-asimuth-integrated-hab-forecast-systems-for-europe-s-atlantic-arc
#3
Julie Maguire, Caroline Cusack, Manuel Ruiz-Villarreal, Joe Silke, Deirdre McElligott, Keith Davidson
Reasons for the emergent interest in HABs are abundant, including concerns associated with human health, adverse effects on biological resources, economic losses attributed to recreation, tourism and seafood related industries, and the cost of maintaining public advisory services and monitoring programs for shellfish toxins and water quality. The impact of HABs can potentially be mitigated by early warning of their development. In this regard the project ASIMUTH (Applied Simulations and Integrated Modelling for the Understanding of Toxic and Harmful algal blooms) was borne in order to develop short term HAB alert systems for Atlantic Europe...
March 2016: Harmful Algae
https://www.readbyqxmd.com/read/28070309/bacterial-etiology-of-bloodstream-infections-and-antimicrobial-resistance-in-dhaka-bangladesh-2005-2014
#4
Dilruba Ahmed, Md Ausrafuggaman Nahid, Abdullah Bashar Sami, Farhana Halim, Nasrin Akter, Tuhin Sadique, Md Sohel Rana, Md Shahriar Bin Elahi, Md Mahbubur Rahman
BACKGROUND: Bloodstream infections due to bacterial pathogens are a major cause of morbidity and mortality in Bangladesh and other developing countries. In these countries, most patients are treated empirically based on their clinical symptoms. Therefore, up to date etiological data for major pathogens causing bloodstream infections may play a positive role in better healthcare management. The aim of this study was to identify the bacterial pathogens causing major bloodstream infections in Dhaka, Bangladesh and determine their antibiotic susceptibility pattern...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/28063462/going-digital-a-narrative-overview-of-the-clinical-and-organisational-impacts-of-ehealth-technologies-in-hospital-practice
#5
Justin Keasberry, Ian A Scott, Clair Sullivan, Andrew Staib, Richard Ashby
Objective The aim of the present study was to determine the effects of hospital-based eHealth technologies on quality, safety and efficiency of care and clinical outcomes.Methods Systematic reviews and reviews of systematic reviews of eHealth technologies published in PubMed/Medline/Cochrane Library between January 2010 and October 2015 were evaluated. Reviews of implementation issues, non-hospital settings or remote care or patient-focused technologies were excluded from analysis. Methodological quality was assessed using a validated appraisal tool...
January 9, 2017: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/28061831/acute-kidney-injury-as-an-independent-risk-factor-for-unplanned-90-day-hospital-readmissions
#6
Simon Sawhney, Angharad Marks, Nick Fluck, David J McLernon, Gordon J Prescott, Corri Black
BACKGROUND: Reducing readmissions is an international priority in healthcare. Acute kidney injury (AKI) is common, serious and also a global concern. This analysis evaluates AKI as a candidate risk factor for unplanned readmissions and determines the reasons for readmissions. METHODS: GLOMMS-II is a large population cohort from one health authority in Scotland, combining hospital episode data and complete serial biochemistry results through data-linkage. 16453 people (2623 with AKI and 13830 without AKI) from GLOMMS-II who survived an index hospital admission in 2003 were used to identify the causes of and predict readmissions...
January 6, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28061818/perspectives-preferences-and-needs-regarding-early-prediction-of-preeclampsia-in-dutch-pregnant-women-a-qualitative-study
#7
Neeltje M T H Crombag, Marije Lamain-de Ruiter, Anneke Kwee, Peter C J I Schielen, Jozien M Bensing, Gerard H A Visser, Arie Franx, Maria P H Koster
BACKGROUND: To improve early risk-identification in pregnancy, research on prediction models for common pregnancy complications is ongoing. Therefore, it was the aim of this study to explore pregnant women's perceptions, preferences and needs regarding prediction models for first trimester screening for common pregnancy complications, such as preeclampsia, to support future implementation. METHOD: Ten focus groups (of which five with primiparous and five with multiparous women) were conducted (n = 45)...
January 7, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28050546/medial-migration-of-the-intramedullary-gamma-3-nail-a-case-report
#8
Ana Costa Pinheiro, Bruno Alpoim, António Félix, Carlos Alves, Cristina Sousa, António Rodrigues
Intertrochanteric femur fractures are very common in patients over 65 years old, and are often associated with osteoporosis. Proximal femoral nails are preferred because of their biomechanical advantages in the treatment of these fractures, especially if the fracture is unstable. However, many complications associated with intramedullary fracture fixation have been described. The medial migration of the intramedullary gamma nail is a rare complication. The authors report an uncommon but potentially fatal complication, medial and intrapelvic migration of the intramedullary Gamma 3 nails, recorded after one month of osteosynthesis...
November 2016: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28049142/danger-associated-molecular-patterns-in-alzheimer-s-disease
#9
REVIEW
Carmen Venegas, Michael T Heneka
Pathogen-associated molecular patterns (PAMPs) and endogenous "danger" signals, known as danger-associated molecular patterns (DAMPs), released from cells alert the innate immune system and activate several signal transduction pathways through interactions with the highly conserved pattern recognition receptors (PRRs). Both PAMPs and DAMPs directly induce proinflammatory cascades and trigger the formation of the inflammasome, mediating the release of cytokines. Here, we highlight the role of DAMPs, including amyloid β (Aβ), high-mobility group box 1 (HMGB1), the S100 family proteins, chromogranin A, and nucleic acids, in the innate-immune activation during the course of Alzheimer disease (AD), the most frequent neurodegenerative disorder...
January 2017: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/28047723/su-f-t-559-high-resolution-scintillating-fiber-array-for-in-vivo-real-time-srs-and-sbrt-patient-qa
#10
T Knewtson, S Pokhrel, S Loyalka, E Izaguirre
PURPOSE: A high-resolution scintillating fiber detector was built for in-vivo real-time patient specific quality assurance (QA). The detector is designed for stereotactic body radiotherapy (SBRT) and stereotactic radiosurgery (SRS) to monitor treatment delivery and detect real-time deviations from planned dose to increase patient safety and treatment accuracy. METHODS: The detector consists of two high-density scintillating fiber arrays layered to form an X-Y grid which can be attached to the accessory tray of a medical linac for SBRT and cone SRS treatment QA...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046279/su-d-209-01-can-fluoroscopic-air-kerma-rates-be-reliably-measured-with-solid-state-meters
#11
C Feng, B Ozus, L Thai, L Wagner
PURPOSE: Ionization chambers remain the standard for calibration of air-kerma rate measuring devices. Despite their strong energy-dependent response, solid state radiation detectors are increasingly used, primarily due to their efficiency in making standardized measurements. To test the reliability of these devices in measuring air-kerma rates, we compared ion chambers measurements with solid-state measurements for various mobile fluoroscopes operated at different beam qualities and air-kerma rates...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045650/reduction-in-alert-fatigue-in-an-assisted-electronic-prescribing-system-through-the-lean-six-sigma-methodology
#12
Mª Jesús Cuéllar Monreal, Jorge Reig Aguado, Isabel Font Noguera, José Luis Poveda Andrés
OBJECTIVE: To reduce the alert fatigue in our Assisted Electronic Prescribing System (AEPS), through the Lean Six Sigma (LSS) methodology. METHOD: An observational (transversal) and retrospective study, in a general hospital with 850 beds and AEPS. The LSS methodology was followed in order to evaluate the alert fatigue situation in the AEPS system, to implement improvements, and to assess outcomes. The alerts generated during two trimesters studied (before and after the intervention) were analyzed...
January 1, 2017: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/28043502/genotypic-analysis-of-multidrug-resistant-tuberculosis-isolates-from-extra-pulmonary-tuberculosis-cases-in-tertiary-care-centers-in-northern-india
#13
Anand K Maurya, Vijaya L Nag, Surya Kant, Ramawadh S Kushwaha, Tapan N Dhole
OBJECTIVE/BACKGROUND: Multidrug-resistant tuberculosis (MDR-TB) is a major public health problem. The diagnosis of MDR-TB is of paramount importance in establishing appropriate clinical management and infection control measures. Rapid detection of MDR-TB allows the establishment of an effective treatment regimen, minimizes the risk of further resistance, and limits the spread of drug-resistant strains. The aim of this study is to determine the genotypic characterization of MDR-TB isolates from extra pulmonary tuberculosis (EPTB) cases in tertiary care centers in Northern India...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28043227/influenza-epidemiology-in-patients-admitted-to-sentinel-australian-hospitals-in-2015-the-influenza-complications-alert-network
#14
Allen C Cheng, Mark Holmes, Dominic E Dwyer, Louis B Irving, Tony M Korman, Sanjaya Senenayake, Kristine K Macartney, Christopher C Blyth, Simon Brown, Grant Waterer, Robert Hewer, N Deborah Friedman, Peter A Wark, Graham Simpson, John Upham, Simon D Bowler, Albert Lessing, Tom Kotsimbos, Paul M Kelly
The Influenza Complications Alert Network (FluCAN) is a sentinel hospital-based surveillance program that operates at sites in all states and territories in Australia. This report summarises the epidemiology of hospitalisations with laboratory-confirmed influenza during the 2015 influenza season. In this observational study, cases were defined as patients admitted to one of the sentinel hospitals with an acute respiratory illness with influenza confirmed by nucleic acid detection. During the period 1 April to 30 October 2015 (the 2015 influenza season), 2,070 patients were admitted with confirmed influenza to one of 17 FluCAN sentinel hospitals...
December 24, 2016: Communicable Diseases Intelligence Quarterly Report
https://www.readbyqxmd.com/read/28042729/critical-laboratory-values-in-hemostasis-towards-consensus
#15
Giuseppe Lippi, Dorothy Adcock, Ana-Maria Simundic, Armando Tripodi, Emmanuel J Favaloro
The term 'critical values' can be defined to entail laboratory test results which significantly lie outside the normal (reference) range and necessitate immediate reporting to safeguard patient health, as well as those displaying a highly and clinically significant variation compared to previous data. The identification and effective communication of "highly pathological" values has engaged the minds of many clinicians, healthcare and laboratory professionals for decades, since these activities are vital to good laboratory practice...
December 31, 2016: Annals of Medicine
https://www.readbyqxmd.com/read/28042124/improvement-in-herpes-zoster-vaccination-in-patients-with-rheumatoid-arthritis-a-quality-improvement-project
#16
Heena Sheth, Larry Moreland, Hilary Peterson, Rohit Aggarwal
OBJECTIVE: To improve herpes zoster (HZ) vaccination rates in high-risk patients with rheumatoid arthritis (RA) being treated with immunosuppressive therapy. METHODS: This quality improvement project was based on the pre- and post-intervention design. The project targeted all patients with RA over the age of 60 years while being treated with immunosuppressive therapy (not with biologics) seen in 13 rheumatology outpatient clinics. The study period was from July 2012 to June 2013 for the pre-intervention and February 2014 to January 2015 for the post-intervention phase...
January 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28025806/the-first-detection-of-potentially-toxic-microcystis-strains-in-two-middle-atlas-mountains-natural-lakes-morocco
#17
Mountasser Douma, Youness Ouahid, Mohammed Loudiki, Francisca F Del Campo, Brahim Oudra
Aguelmam Azizgza (LAZ) and Dayet Afourgah (DAF) are two Moroccan natural lakes located in a humid hydrographic basin of the Middle Atlas Mountains. Both are considered important reservoirs of plant and animal biodiversity. In addition, they are extensively used for recreational and fishing activities and as a water source for irrigation of agricultural crops. Recurrent cyanobacteria scum episodes in the two water bodies have been reported, Microcystis being the main genus in the scums. Here, we report on the toxic potential of three Microcystis aeruginosa strains isolated from those lakes: Mic LAZ and Mic B7 from LAZ and Mic DAF isolated from DAF...
January 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28011018/a-ternary-classification-using-machine-learning-methods-of-distinct-estrogen-receptor-activities-within-a-large-collection-of-environmental-chemicals
#18
Quan Zhang, Lu Yan, Yan Wu, Li Ji, Yuanchen Chen, Meirong Zhao, Xiaowu Dong
Endocrine-disrupting chemicals (EDCs), which can threaten ecological safety and be harmful to human beings, have been cause for wide concern. There is a high demand for efficient methodologies for evaluating potential EDCs in the environment. Herein an evaluation platform was developed using novel and statistically robust ternary models via different machine learning models (i.e., linear discriminant analysis, classification and regression tree, and support vector machines). The platform is aimed at effectively classifying chemicals with agonistic, antagonistic, or no estrogen receptor (ER) activities...
December 20, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/28009344/a-model-for-continuous-monitoring-of-patients-with-major-depression-in-short-and-long-term-periods
#19
Francisco Mugica, Àngela Nebot, Solmaz Bagherpour, Luisa Baladón, Antonio Serrano-Blanco
BACKGROUND AND OBJECTIVE: Major depressive disorder causes more human suffering than any other disease affecting humankind. It has a high prevalence and it is predicted that it will be among the three leading causes of disease burden by 2030. The prevalence of depression, all of its social and personal costs, and its recurrent characteristics, put heavy constraints on the ability of the public healthcare system to provide sufficient support for patients with depression. In this research, a model for continuous monitoring and tracking of depression in both short-term and long-term periods is presented...
December 16, 2016: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/28008861/delayed-diagnosis-of-a-17-hydroxylase-17-20-lyase-deficient-case-presented-with-46-xy-female-low-normal-potassium-can-alert-clinician
#20
Emine Çamtosun, Zeynep Şıklar, Serdar Ceylaner, Pınar Kocaay, Merih Berberoğlu
17-hydroxylase/17,20-lyase deficiency (17OHD) is a rare autosomal recessive defect in adrenal and gonadal steroidogenesis, causes absence of secondary sexual characteristics frequently associated with hypertension and hyperkalemia. Here we report a 46, XY case, who had normal potassium levels and without hypertension. Here we present a 2,5 years old female admitted with female external genitalia and inguinal swelling. Pathology of biopsy revealed that this gonad is a testis. Karyotype was 46, XY. She had no hypertension and no hypokalemia...
December 23, 2016: Journal of Clinical Research in Pediatric Endocrinology
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