keyword
MENU ▼
Read by QxMD icon Read
search

STEC

keyword
https://www.readbyqxmd.com/read/29230401/shiga-toxin-producing-escherichia-coli-o157-shedding-dynamics-in-an-australian-beef-herd
#1
Christina Ahlstrom, Petra Muellner, Geraldine Lammers, Meghan Jones, Sophie Octavia, Ruiting Lan, Jane Heller
Shiga toxin-producing Escherichia coli (STEC) O157 is an important foodborne pathogen that can be transmitted to humans both directly and indirectly from the feces of beef cattle, its primary reservoir. Numerous studies have investigated the shedding dynamics of E. coli O157 by beef cattle; however, the spatiotemporal trends of shedding are still not well understood. Molecular tools can increase the resolution through the use of strain typing to explore transmission dynamics within and between herds and identify strain-specific characteristics that may influence pathogenicity and spread...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29217302/c-source-metabolic-profilings-of-foodborne-shiga-toxin-producing-e-coli-match-serogroup-differentiations-and-highlight-functional-adaptations
#2
Stéphane Kerangart, Benoit Cournoyer, Estelle Loukiadis
The tropism of pathogenic STEC for foodstuffs and cattle reservoir is related to functional specializations. An investigation of C-source utilization patterns among and between STEC serogroups was performed using omnilog phenotypic microarrays (OM). OM functional groupings were compared with STEC phylogroups, seropathotypes, EFSA's molecular risk assessment groups and serogroups. OM INT reduction activities of 37 STEC strains growing on 190 C-substrates were compared. Each strain had its own specific C-utilization profile but 23% of the substrates was used by all strains, 47% by none, and 30% was variably metabolized...
December 4, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29216383/genetic-susceptibility-to-hemolytic-uremic-syndrome-after-shiga-toxin-producing-escherichia-coli-stec-infection-a-centers-for-disease-control-and-prevention-cdc-foodnet-study
#3
Asha R Kallianpur, Yuki Bradford, Rajal K Mody, Katie N Garman, Nicole Comstock, Sarah L Lathrop, Carol Lyons, Amy Saupe, Katie Wymore, Jeffrey A Canter, Lana M Olson, Amanda Palmer, Timothy F Jones
Background: Post-diarrheal hemolytic-uremic syndrome (D+HUS) following Shiga toxin-producing Escherichia coli (STEC) infection is a serious condition lacking specific treatment. Host immune dysregulation and genetic susceptibility to complement hyperactivation are implicated in non-STEC-related HUS. However, genetic susceptibility to D+HUS remains largely uncharacterized. Methods: Patients with culture-confirmed STEC diarrhea, identified through the CDC FoodNet surveillance system (2007-2012), were serotyped and classified by laboratory and/or clinical criteria as suspected, probable, or confirmed D+HUS, or as controls and genotyped at 200 loci linked to non-diarrheal HUS or similar pathologies...
December 6, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29215775/an-assessment-of-the-microbiological-quality-and-safety-of-raw-drinking-milk-on-retail-sale-in-england
#4
Caroline Willis, Frieda Jørgensen, Heather Aird, Nicola Elviss, Andrew Fox, Claire Jenkins, Deborah Fenelon, Lorraine Sadler-Reeves, Jim McLauchlin
AIMS: This study aimed to review the microbiological results for raw drinking milk (RDM) samples submitted to Public Health England laboratories between 2014 and 2016 in order to produce up-to-date data on the microbiological safety of RDM and inform future risk assessments on its sale. METHODS AND RESULTS: A total of 902 samples of RDM were collected from retail sale in England for microbiological examination. Overall, 454/770 samples (59.0%) taken for routine monitoring were of a satisfactory quality, whilst eight (1...
December 7, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29215770/molecular-ecology-of-listeria-spp-salmonella-escherichia-coli-o157-h7-and-non-o157-shiga-toxin-producing-escherichia-coli-in-pristine-natural-environments-in-northern-colorado
#5
Christina A Ahlstrom, Clyde S Manuel, Henk C Den Bakker, Martin Wiedmann, Kendra K Nightingale
AIMS: Molecular subtyping is commonly used in foodborne disease surveillance and microbial source tracking. There is a knowledge gap regarding the molecular ecology of foodborne pathogens in non-food associated environments. The objective of this study was to isolate and subtype foodborne pathogens from pristine natural environments with minimal anthropogenic inputs. MATERIALS AND RESULTS: Five locations (wilderness areas) in Northern Colorado were sampled during the spring, summer, and fall over a two-year period...
December 7, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29214442/shiga-toxin-triggers-endothelial-and-podocyte-injury-the-role-of-complement-activation
#6
REVIEW
Carlamaria Zoja, Simona Buelli, Marina Morigi
Shiga toxin (Stx)-producing Escherichia coli (STEC) is the offending agent in post-diarrhea-associated hemolytic uremic syndrome (HUS), a disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and acute kidney failure, with thrombi occluding the renal microvasculature. Endothelial dysfunction has been recognized as the trigger event in the development of microangiopathic processes. Glomerular endothelial cells are susceptible to the toxic effects of Stxs that, via nuclear factor kappa B (NF-κB) activation, induce the expression of genes encoding for adhesion molecules and chemokines, culminating in leukocyte adhesion and platelet thrombus formation on the activated endothelium...
December 6, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29214000/role-of-antigen-43-on-biofilm-formation-and-horizontal-antibiotic-resistance-gene-transfer-in-non-o157-shiga-toxin-producing-escherichia-coli-strains
#7
Roholla Taghadosi, Mohammad Reza Shakibaie, Reza Ghanbarpour, Hossein Hosseini-Nave
Background and Objectives: The objectives of this study were to evaluate the antibiotic resistance profiles, biofilm formation, presence of antigen 43 (Ag43) gene, and transfer of antibiotic resistance phenotype among non-O157 Shiga toxin producing Escherichia coli (STEC). Materials and Methods: From October 2014 to November 2015 a total of 276 stool samples were collected from healthy calves, goats and 395 patients with the sign of nonbloody diarrhea and screened for presence of stx and serotype O157 genes by polymerase chain reaction (PCR) technique...
April 2017: Iranian Journal of Microbiology
https://www.readbyqxmd.com/read/29212810/heme-oxygenase-1-is-a-potent-inhibitor-of-placental-ischemia-mediated-endothelin-1-production-in-cultured-human-glomerular-endothelial-cells
#8
Bhavisha A Bakrania, Frank T Spradley, Simon C Satchell, David E Stec, John M Rimoldi, Rama S V Gadepalli, Joey P Granger
Preeclampsia is a pregnancy-specific disorder of maternal hypertension and reduced renal hemodynamics linked to reduced endothelial function. Placental ischemia is thought to be the culprit of this disease, as it causes the release of factors like tumor necrosis factor (TNF)-α that induce vascular endothelin-1 (ET-1) production. Interestingly, placental ischemia-induced hypertension in rats (reduced uterine perfusion pressure, RUPP model) is abolished by ETA receptor blockade, suggesting a critical role for ET-1...
December 6, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/29205193/molecular-characterization-of-locus-of-enterocyte-effacement-pathogenicity-island-in-shigatoxic-escherichia-coli-isolated-from-human-cattle-in-west-bengal-india
#9
Suresh Chandra Das, Thandavanaryanalu Ramamurthy, Santanu Ghosh, Gururaja Perumal Pazhani, Tista Sen, Raghubir Singh
BACKGROUND & OBJECTIVES: Shigatoxic Escherichia coli (STEC) recovered from dairy animals of Kolkata, India, harboured the putative virulence genes; however, the animals did not exhibit clinical symptoms. Similarly, human isolates in this locality also showed variations in degree of symptoms. Hence, this study was designed to know the presence of recognized gene(s) in the locus of enterocyte effacement (LEE) pathogenicity island in these STEC isolates and functional status of the cardinal gene (eae) related to pathogenicity...
July 2017: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/29195108/novel-combined-index-of-cardiometabolic-risk-related-to-periarterial-fat-improves-the-clinical-prediction-for-coronary-artery-disease-complexity
#10
Maciej Haberka, Michał Lelek, Tomasz Bochenek, Adam Kowalówka, Rafał Młynarski, Katarzyna Mizia-Stec, Zbigniew Gąsior
BACKGROUND AND AIMS: Cardiovascular (CV) risk assessment based on conventional risk factors has a limited performance in the prediction of obstructive coronary artery disease (CAD). Therefore, our aim was to provide a complete assessment on the associations between single or combined cardiovascular ultrasound indexes and the complexity of CAD in high and very-high risk patients. METHODS: Two hundred fifteen patients scheduled for elective coronary angiography were enrolled in the study (F/M: 80/135 pts; age: 61...
September 15, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29184377/virulence-and-extended-spectrum-%C3%AE-lactamase-encoding-genes-in-escherichia-coli-recovered-from-chicken-meat-intended-for-hospitalized-human-consumption
#11
Gamal A Younis, Rasha M Elkenany, Mohamed A Fouda, Noura F Mostafa
Aim: This study describes the prevalence of Escherichia coli in frozen chicken meat intended for human consumption with emphasis on their virulence determinants through detection of the virulence genes and recognition of the extended-spectrum β-lactamase (ESBL) encoding genes (blaOXA and blaTEM genes). Materials and Methods: A total of 120 frozen chicken meat samples were investigated for isolation of E. coli. All isolates were subjected to biochemical and serological tests...
October 2017: Veterinary World
https://www.readbyqxmd.com/read/29184374/molecular-characterization-of-escherichia-coli-recovered-from-traditional-milk-products-in-kashan-iran
#12
Farhad Sharafati Chaleshtori, Navid Mazroii Arani, Esmat Aghadavod, Afshin Naseri, Reza Sharafati Chaleshtori
Aim: Shiga toxigenic Escherichia coli (STEC) strains as emerging groups of foodborne pathogens are responsible for most foodborne illnesses. The aim of this study was to determine the antibiotic resistance pattern in STEC isolated from traditional milk products and their molecular characterization. Materials and Methods: A total of 116 samples were randomly purchased from local markets in Kashan, Iran, and evaluated for the occurrence of STEC by culturing and molecular methods...
October 2017: Veterinary World
https://www.readbyqxmd.com/read/29184370/occurrence-of-virulent-and-antibiotic-resistant-shiga-toxin-producing-escherichia-coli-in-some-food-products-and-human-stool-in-egypt
#13
Osman Mohamed Hamed, Maha Ahmed Sabry, Nawal A Hassanain, Eman Hamza, Ahmed G Hegazi, Marwa Badawy Salman
Aim: Shiga toxin-producing Escherichia coli (STEC) represent a severe public health issue worldwide, causing life-threatening diseases in the human gastrointestinal tract. This study aimed to determine the occurrence of virulent and antibiotic-resistant STEC in retail meat and milk products and human stool samples and to characterize the genes encoding for virulence and antibiotic resistance among the identified STEC isolates. Materials and Methods: A total of 260 food samples were randomly collected from retail markets in different localities of El Giza Governorate, Egypt...
October 2017: Veterinary World
https://www.readbyqxmd.com/read/29183554/molecular-characterisation-of-human-shiga-toxin-producing-escherichia-coli-o26-strains-results-of-an-outbreak-investigation-romania-february-to-august-2016
#14
Codruţa-Romaniţa Usein, Adriana Simona Ciontea, Cornelia Mãdãlina Militaru, Maria Condei, Sorin Dinu, Mihaela Oprea, Daniela Cristea, Valeria Michelacci, Gaia Scavia, Lavinia Cipriana Zota, Alina Zaharia, Stefano Morabito
IntroductionAt the beginning of 2016, an increase in paediatric haemolytic uremic syndrome (HUS) cases was observed in Romania. The microbiological investigations allowed isolation of Shiga toxin-producing Escherichia coli (STEC) O26 as the causative agent from most cases. Methods: An enhanced national surveillance of HUS and severe diarrhoea was established across the country following the identification of the first cases and was carried out until August 2016. A total of 15 strains were isolated from 10 HUS and five diarrhoea cases...
November 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/29179123/spatial-and-temporal-variability-of-bacterial-indicators-and-pathogens-in-six-california-reservoirs-during-extreme-drought
#15
Melissa L Partyka, Ronald F Bond, Jennifer A Chase, Edward R Atwill
California has one of the largest systems of surface water reservoirs in the world, providing irrigation water to California's agriculturally productive Central Valley. Irrigation water is recognized as a vehicle for the microbial contamination of raw produce and must be monitored according to new federal regulation. The purpose of this study was to further understanding of the variability of fecal indicator bacteria (Escherichia coli and fecal coliforms) and pathogens (E. coli O157:H7 (O157), non-O157 Shiga toxin-producing E...
November 16, 2017: Water Research
https://www.readbyqxmd.com/read/29168539/severe-degenerative-aortic-stenosis-with-preserved-ejection-fraction-does-not-change-adipokines-serum-levels
#16
Katarzyna Mizia-Stec, Tomasz Bochenek, Błażej Kusz, Magdalena Mizia, Agnieszka Sikora-Puz, Klaudia Gieszczyk-Strózik
BACKGROUND: The role of the adipokines in the pathogenesis of aortic stenosis (AS) is not well established. The aim was to evaluate the relationship between adipokines and clinical characteristics as well as echocardiographic indices and noninvasive markers of vascular remodeling in patients with severe AS with preserved ejection fraction (EF). METHODS: Sixty-five patients (F/M: 38/27; age: 68.3 ± 9.0 years; body mass index [BMI]: 29.6 ± 4.3 kg/m²) with severe AS with preserved EF: 33 patients with paradoxical low-flow low-gradient AS (PLFLG AS) and 32 patients with normal flow high-gradient AS (NFHG AS) were prospectively enrolled into the study...
November 23, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/29166238/shiga-toxin-producing-e-coli-infections-associated-with-flour
#17
Samuel J Crowe, Lyndsay Bottichio, Lauren N Shade, Brooke M Whitney, Nereida Corral, Beth Melius, Katherine D Arends, Danielle Donovan, Jolianne Stone, Krisandra Allen, Jessica Rosner, Jennifer Beal, Laura Whitlock, Anna Blackstock, June Wetherington, Lisa A Newberry, Morgan N Schroeder, Darlene Wagner, Eija Trees, Stelios Viazis, Matthew E Wise, Karen P Neil
BACKGROUND: In 2016, a multijurisdictional team investigated an outbreak of Shiga toxin-producing Escherichia coli (STEC) serogroup O121 and O26 infections linked to contaminated flour from a large domestic producer. METHODS: A case was defined as infection with an outbreak strain in which illness onset was between December 21, 2015, and September 5, 2016. To identify exposures associated with the outbreak, outbreak cases were compared with non-STEC enteric illness cases, matched according to age group, sex, and state of residence...
November 23, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29163651/molecular-detection-of-virulence-genes-and-multi-drug-resistance-patterns-in-escherichia-coli-stec-in-clinical-bovine-mastitis-alborz-province-iran
#18
M Tavakoli, H Pourtaghi
The aim of this study was to identify virulence genes and antimicrobial resistance of Escherichia coli isolated from bovine clinical mastitis in dairy herds in Iran. Sampling was done from 86 inflamed quarters of dairy cows in 8 commercial farms of Alborz province, Iran in summer 2015. Shiga toxin-producing E. coli (STEC) virulence genes were detected by multiplex PCR and multi-drug resistance profiles were confirmed using disk diffusion method. Among 60 E. coli isolated from examined samples, 13 (21.6%) of them were STEC...
2017: Iranian Journal of Veterinary Research
https://www.readbyqxmd.com/read/29158813/vascularized-tissue-engineered-model-for-studying-drug-resistance-in-neuroblastoma
#19
A Villasante, K Sakaguchi, J Kim, N K Cheung, M Nakayama, H Parsa, T Okano, T Shimizu, G Vunjak-Novakovic
Neuroblastoma is a vascularized pediatric tumor derived from neural crest stem cells that displays vasculogenic mimicry and can express a number of stemness markers, such as SOX2 and NANOG. Tumor relapse is the major cause of succumbing to this disease, and properties attributed to cancer stem-like cells (CSLC), such as drug-resistance and cell plasticity, seem to be the key mechanisms. However, the lack of controllable models that recapitulate the features of human neuroblastoma limits our understanding of the process and impedes the development of new therapies...
2017: Theranostics
https://www.readbyqxmd.com/read/29148397/evolutionary-context-of-non-sorbitol-fermenting-shiga-toxin-producing-escherichia-coli-o55-h7
#20
Kyle Schutz, Lauren A Cowley, Sharif Shaaban, Anne Carroll, Eleanor McNamara, David L Gally, Gauri Godbole, Claire Jenkins, Timothy J Dallman
In July 2014, an outbreak of Shiga toxin-producing Escherichia coli (STEC) O55:H7 in England involved 31 patients, 13 (42%) of whom had hemolytic uremic syndrome. Isolates were sequenced, and the sequences were compared with publicly available sequences of E. coli O55:H7 and O157:H7. A core-genome phylogeny of the evolutionary history of the STEC O55:H7 outbreak strain revealed that the most parsimonious model was a progenitor enteropathogenic O55:H7 sorbitol-fermenting strain, lysogenized by a Shiga toxin (Stx) 2a-encoding phage, followed by loss of the ability to ferment sorbitol because of a non-sense mutation in srlA...
December 2017: Emerging Infectious Diseases
keyword
keyword
116468
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"