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https://www.readbyqxmd.com/read/29331727/individual-variation-in-working-memory-is-associated-with-fear-extinction-performance
#1
Daniel M Stout, Dean T Acheson, Tyler M Moore, Ruben C Gur, Dewleen G Baker, Mark A Geyer, Victoria B Risbrough
PTSD has been associated consistently with abnormalities in fear acquisition and extinction learning and retention. Fear acquisition refers to learning to discriminate between threat and safety cues. Extinction learning reflects the formation of a new inhibitory-memory that competes with a previously learned threat-related memory. Adjudicating the competition between threat memory and the new inhibitory memory during extinction may rely, in part, on cognitive processes such as working memory (WM). Despite significant shared neural circuits and signaling pathways the relationship between WM, fear acquisition, and extinction is poorly understood...
January 5, 2018: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/29327634/clearing-the-confusion-about-self-directed-learning-and-self-regulated-learning
#2
Roghayeh Gandomkar, John Sandars
Self-Directed Learning (SDL) and Self-Regulated Learning (SRL) are often used without a clear distinction, leading to confusion in understanding and the use of inappropriate measurement tools. SDL is a general approach to learning and can be identified using 'aptitude' questionnaires but SRL is a dynamic and context specific learning process and requires 'event' measures, such as microanalysis. These differences have implications for research and remediation.
January 12, 2018: Medical Teacher
https://www.readbyqxmd.com/read/29317519/%C3%AE-arrestin-biased-%C3%AE-adrenergic-signaling-promotes-extinction-learning-of-cocaine-reward-memory
#3
Bing Huang, Youxing Li, Deqin Cheng, Guanhong He, Xing Liu, Lan Ma
Extinction learning of cocaine-associated contextual cues can help prevent cocaine addicts from relapsing. Pharmacological manipulation of β-adrenergic receptor (β-AR) during extinction learning is being developed as a potential strategy to treat drug addiction. We demonstrated that the extinction learning of cocaine-associated memory was mediated by β-arrestin2-biased but not heterotrimeric guanine nucleotide-binding protein (G protein)-dependent β-adrenergic signaling. We found that administration of the nonbiased β-AR antagonist propranolol, but not the G protein-biased β-AR antagonist carvedilol, blocked extinction learning of cocaine-conditioned place preference and the associated ERK activation in the infralimbic prefrontal cortex...
January 9, 2018: Science Signaling
https://www.readbyqxmd.com/read/29275907/a-multimodal-approach-improves-american-board-of-surgery-in-training-examination-scores
#4
Mary A Decoteau, Louis Rivera, Kristina Umali, Arden B Chan, Peter Soballe, Romeo C Ignacio
BACKGROUND: There are several factors that influence ABSITE scores, but the optimal approach for remediation of poor scores is unclear. METHODS: A structured academic curriculum and focused remediation program (FRP) were implemented to improve academic performances. Within a 15-year period, ABSITE and American Board of Surgery qualifying exam (ABS QE) results were compared before and after the establishment of the program using a paired T-test. Subgroup analysis was performed for residents who completed the FRP...
December 21, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/29243386/global-approaches-to-early-learning-research-and-practice-integrative-commentary
#5
Nicole Landi, Laurie E Cutting
This commentary presents highlights from the seven articles in this volume, along with a synthesis of take-home points that can be used to inform policy and practice. Across each article there is a story of both successes and the challenges of ongoing work that seeks to enhance children's development in diverse and challenging environments across the globe. Although the topics covered in this volume range from development of early self-regulation and executive function to the use of technology to aid literacy acquisition in remote areas, each points to the need for systems-level coordination and sustained commitment to reach children at risk...
December 2017: New Directions for Child and Adolescent Development
https://www.readbyqxmd.com/read/29242080/feasibility-and-acceptability-of-mindfulness-for-survivors-of-homicide-and-their-providers
#6
Stephanie Hartwell, Jeroan Allison, Bonita Jones, Rachel Rodrigues, Clementina Chery, Julianna Andrews, Carl Fulwiler
PURPOSE: This study uses participatory research methods with survivors of homicide and their service providers to explore the feasibility and acceptability of a culturally adapted mindfulness intervention for stress reduction and resilience in homicide survivors. PROCEDURES: Our mixed methods approach included: (a) previewing a Mindfulness-Based Stress Reduction program with providers and survivors; (b) using their iterative feedback during focus groups to revise the curriculum; and (c) studying the acceptability of the adapted curriculum for survivors through focus group and standardized data collection...
November 2, 2017: Explore: the Journal of Science and Healing
https://www.readbyqxmd.com/read/29230856/the-role-of-the-assessment-policy-in-the-relation-between-learning-and-performance
#7
Rob Kickert, Karen M Stegers-Jager, Marieke Meeuwisse, Peter Prinzie, Lidia R Arends
CONTEXT: Optimising student learning and academic performance is a continuous challenge for medical schools. The assessment policy may influence both learning and performance. Previously, the joint contribution of self-regulated learning (SRL) and participation in scheduled learning activities towards academic performance has been reported. However, little is known about the relationships between SRL, participation and academic performance under different assessment policies. OBJECTIVES: The goal of this study was to investigate differences in average scores of SRL, participation and academic performance of students under two assessment policies: (i) a conjunctive lower stakes, lower performance standard (old) assessment policy and (ii) a compensatory higher stakes, higher performance standard (new) assessment policy...
December 11, 2017: Medical Education
https://www.readbyqxmd.com/read/29229706/causal-evidence-for-learning-dependent-frontal-lobe-contributions-to-cognitive-control
#8
Paul S Muhle-Karbe, Jiefeng Jiang, Tobias Egner
The lateral prefrontal cortex (LPFC) plays a central role in the prioritization of sensory input based on task-relevance. Such top-down control of perception is of fundamental importance in goal-directed behavior, but can also be costly when deployed excessively, necessitating a mechanism that regulates control engagement to align it with changing environmental demands. We have recently introduced the "flexible control model," which explains this regulation as resulting from a self-adjusting reinforcement-learning mechanism that infers latent statistical structure in dynamic task environments to predict forthcoming states...
December 11, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29228830/twelve-tips-on-how-to-provide-self-regulated-learning-srl-enhanced-feedback-on-clinical-performance
#9
Heather Leggett, John Sandars, Trudie Roberts
The provision of self-regulated learning (SRL) enhanced feedback on performing clinical skills and making a clinical diagnosis recognizes the importance of feedback on the use of key SRL processes. In contrast to the broader concept of self-directed learning, SRL has a specific focus on the individual learner's approach to achieve a task, including their planning, self-monitoring, and future adaptations. The key SRL processes can be identified using structured microanalysis during the clinical task and feedback to the learner using the tips outlined in this article...
December 11, 2017: Medical Teacher
https://www.readbyqxmd.com/read/29228794/learning-to-breathe-a-pilot-study-of-a-mindfulness-based-intervention-to-support-marginalized-youth
#10
Amy L Eva, Natalie M Thayer
Mindfulness-based curricular interventions can support adolescents who are at risk of school failure as they negotiate the transition from high school into young adulthood. Researchers hypothesized that a 6-week mindfulness-based intervention would lower participants' perceived stress while increasing their reported levels of self-esteem. Participants (N = 23) ranged in age from 17 to 20 years while the majority were male students of color. Pre- and postintervention survey mean responses revealed statistically significant differences on the Single-Item Self-Esteem Scale and 3 items on the Perceived Stress Scale (with small to moderate effect sizes)...
January 1, 2017: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/29226224/an-application-of-programmatic-assessment-for-learning-pal-system-for-general-practice-training
#11
Lambert Schuwirth, Nyoli Valentine, Paul Dilena
Aim: Programmatic assessment for learning (PAL) is becoming more and more popular as a concept but its implementation is not without problems. In this paper we describe the design principles behind a PAL program in a general practice training context. Design principles: The PAL program was designed to optimise the meaningfulness of assessment information for the registrar and to make him/her use that information to self regulate their learning. The main principles in the program were cognitivist and transformative...
2017: GMS Journal for Medical Education
https://www.readbyqxmd.com/read/29209260/awareness-and-awakening-a-narrative-oriented-inquiry-of-undergraduate-students-development-of-mindful-agency-in-china
#12
Qing Wang, Ho Chung Law, Yan Li, Zhanfei Xu, Weiguo Pang
The article explores undergraduate students' experiences of developing mindful agency as a positive learning disposition, their perceived change as a learner, and the possible impact of mindful agency coaching on students' learning and personal growth, using a narrative research method. Seventy Chinese undergraduate students generated personal reflective journals and eight participants' journals were selected to enter into the narrative-oriented inquiry. Our analysis revealed a number of primary themes based on which we produced a meta-story...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29209251/social-cognition-and-executive-functions-as-key-factors-for-effective-pedagogy-in-higher-education
#13
Rut Correia, Gorka Navarrete
Higher education (HE) faces the challenge of responding to an increasing diversity. In this context, more attention is being paid to teachers and teaching skills positively related to students learning. Beyond the knowledges identified as key components of an effective teacher, teachers also need to be capable of unraveling what their students think and believe, and how they accommodate the new information. More importantly, teachers need to be able to adapt their own teaching to their audience's needs. In learners, social cognition (SC) has been related to a better receptivity to the different teacher-student interactions...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29202017/molecular-motor-dnm1-synergistically-induces-membrane-curvature-to-facilitate-mitochondrial-fission
#14
Michelle W Lee, Ernest Y Lee, Ghee Hwee Lai, Nolan W Kennedy, Ammon E Posey, Wujing Xian, Andrew L Ferguson, R Blake Hill, Gerard C L Wong
Dnm1 and Fis1 are prototypical proteins that regulate yeast mitochondrial morphology by controlling fission, the dysregulation of which can result in developmental disorders and neurodegenerative diseases in humans. Loss of Dnm1 blocks the formation of fission complexes and leads to elongated mitochondria in the form of interconnected networks, while overproduction of Dnm1 results in excessive mitochondrial fragmentation. In the current model, Dnm1 is essentially a GTP hydrolysis-driven molecular motor that self-assembles into ring-like oligomeric structures that encircle and pinch the outer mitochondrial membrane at sites of fission...
November 22, 2017: ACS Central Science
https://www.readbyqxmd.com/read/29198229/improvement-of-self-regulated-learning-in-mathematics-through-a-hypermedia-application-differences-based-on-academic-performance-and-previous-knowledge
#15
Marisol Cueli, Celestino Rodríguez, Débora Areces, Trinidad García, Paloma González-Castro
Self-regulation on behalf of the student is crucial in learning Mathematics through hypermedia applications and is an even greater challenge in these IT environments. Two aims are formulated. First, to analyze the effectiveness of a hypermedia tool in improving perceived knowledge of self-regulatory strategies and the perceived usage of the planning, executing and assessment strategy on behalf of students with low, medium and high levels of academic performance. Second, to analyze the effectiveness of the hypermedia tool in improving perceived usage of the strategy for planning, monitoring and evaluating on behalf of students with a perceived knowledge (low, medium and high)...
December 4, 2017: Spanish Journal of Psychology
https://www.readbyqxmd.com/read/29191571/distinguish-self-and-hetero-perceived-stress-through-behavioral-imaging-and-physiological-features
#16
Michel Spodenkiewicz, Jonathan Aigrain, Nadège Bourvis, Séverine Dubuisson, Mohamed Chetouani, David Cohen
Stress reactivity is a complex phenomenon associated to multiple and multimodal expressions. Response to stressors has an obvious survival function and may be seen as an internal regulation to adapt to threat or danger. The intensity of this internal response can be assessed as the self-perception of the stress response. In species with social organization, this response also serves a communicative function, so-called hetero-perception. Our study presents multimodal stress detection assessment - a new methodology combining behavioral imaging and physiological monitoring for analyzing stress from these two perspectives...
November 27, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29183363/motivation-and-academic-performance-of-medical-students-from-ethnic-minorities-and-majority-a-comparative-study
#17
Ulviye Isik, Anouk Wouters, Marieke M Ter Wee, Gerda Croiset, Rashmi A Kusurkar
BACKGROUND: Medical students from ethnic minorities underperform in knowledge and skills assessments both in pre-clinical and clinical education compared to the ethnic majority group. Motivation, which influences learning and academic performance of medical students, might play an important role in explaining these differences, but is under-investigated. This study aimed to compare two types of motivation (autonomous and controlled) of ethnic minority (Western and non-Western) and majority (Dutch) students, and their association with academic performance...
November 28, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/29172856/contextual-attributes-promote-or-hinder-self-regulated-learning-a-qualitative-study-contrasting-rural-physicians-with-undergraduate-learners-in-japan
#18
Yasushi Matsuyama, Motoyuki Nakaya, Hitoaki Okazaki, Jimmie Leppink, Cees van der Vleuten
BACKGROUND AND OBJECTIVES: Previous studies support the notion that East Asian medical students do not possess sufficient self-regulation for postgraduate clinical training. However, some East Asian physicians who are employed in geographically isolated and educationally underserved rural settings can self-regulate their study during the early phase of their postgraduate career. To explore the contextual attributes that contribute to self-regulated learning (SRL), we examined the differences in self-regulation between learning as an undergraduate and in a rural context in East Asia...
November 26, 2017: Medical Teacher
https://www.readbyqxmd.com/read/29167327/learning-induced-modulation-of-the-effect-of-endocannabinoids-on-inhibitory-synaptic-transmission
#19
Sourav Ghosh, Iris Reuveni, Samaa Zidan, Raphael Lamprecht, Edi Barkai
Endocannabinoids are key modulators that regulate central brain functions and behaviours, including learning and memory. At the cellular and molecular levels, endocannabinoids are potent modulators of excitatory and inhibitory synaptic function. Most effects of cannabinoids are thought to be mediated via G protein-coupled cannabinoids receptors. In particular, cannabinoids released from post-synaptic neurons are suggested to act as retrograde messengers, activating presynaptic Type-1 Cannabinoid receptors (CB1R), thereby inducing suppression of synaptic release...
November 22, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29166220/does-the-cognitive-reflection-test-actually-capture-heuristic-versus-analytic-reasoning-styles-in-older-adults
#20
Christopher Hertzog, R Marit Smith, Robert Ariel
Background/Study Context: This study evaluated adult age differences in the original three-item Cognitive Reflection Test (CRT; Frederick, 2005, The Journal of Economic Perspectives, 19, 25-42) and an expanded seven-item version of that test (Toplak et al., 2013, Thinking and Reasoning, 20, 147-168). The CRT is a numerical problem-solving test thought to capture a disposition towards either rapid, intuition-based problem solving (Type I reasoning) or a more thoughtful, analytical problem-solving approach (Type II reasoning)...
November 22, 2017: Experimental Aging Research
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