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Canine dog orthopedic

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https://www.readbyqxmd.com/read/28576271/physical-rehabilitation-for-the-management-of-canine-hip-dysplasia
#1
REVIEW
David L Dycus, David Levine, Denis J Marcellin-Little
Hip dysplasia is among the most common orthopedic conditions affecting dogs. Joint laxity is responsible for abnormal development of the femoral head and acetabulum, leading to excessive wear of the articular cartilage. Wear leads to secondary osteoarthritis. Rehabilitation is either conservative or after surgical management. Conservative rehabilitation therapies are directed at decreasing pain, improving hip range of motion (ROM), and building or maintaining muscle mass. Postoperatively, rehabilitation focuses on decreasing postoperative pain and inflammation, improving comfort and limb use, and protecting the surgical site...
July 2017: Veterinary Clinics of North America. Small Animal Practice
https://www.readbyqxmd.com/read/28460694/etiopathogenesis-of-canine-hip-dysplasia-prevalence-and-genetics
#2
REVIEW
Michael D King
First identified in 1935, canine hip dysplasia is thought to be the most common orthopedic condition diagnosed in the dog. It is most prevalent in large and giant breed dogs, with a complex polygenic mode of inheritance, and relatively low heritability. External factors including caloric intake when growing have a significant effect on phenotypic expression. Initial joint laxity progresses to osteoarthritis due to subluxation and abnormal wearing. Selective breeding programs to attempt to decrease prevalence have shown modest results so far...
July 2017: Veterinary Clinics of North America. Small Animal Practice
https://www.readbyqxmd.com/read/28386583/the-demographics-of-canine-hip-dysplasia-in-the-united-states-and-canada
#3
Randall T Loder, Rory J Todhunter
Canine hip dysplasia (CHD) is a common problem in veterinary medicine. We report the demographics of CHD using the entire hip dysplasia registry from the Orthopedic Foundation for Animals, analyzing differences by breed, sex, laterality, seasonal variation in birth, and latitude. There were 921,046 unique records. Each dog was classified using the American Kennel Club (AKC) and Fédération Cynologique Internationale (FCI) systems. Statistical analysis was performed with bivariate and logistic regression procedures...
2017: Journal of veterinary medicine
https://www.readbyqxmd.com/read/28334450/short-term-effects-of-arthrotomy-with-and-without-infrapatellar-fat-pad-resection-on-the-normal-canine-stifle
#4
Yukihiro Fujita, Tetsuya Nakajo, Makoto Muto
OBJECTIVE: To investigate the short-term effects of infrapatellar fat pad (IFP) resection in normal dogs. STUDY DESIGN: Experimental in vivo study. ANIMALS: Five normal adult female beagle dogs. METHODS: The IFP was resected via arthrotomy in the left stifle joint (experimental side) while the right stifle underwent arthrotomy alone (sham side). An orthopedic examination was performed every week for 4 weeks and synovial fluid was analyzed before and 4 weeks after the procedure...
March 23, 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28291395/prospective-evaluation-of-intra-articular-dextrose-prolotherapy-for-treatment-of-osteoarthritis-in-dogs
#5
RANDOMIZED CONTROLLED TRIAL
J Matthew Sherwood, James K Roush, Laura J Armbrust, Walter C Renberg
The objective of this study was to evaluate intra-articular dextrose prolotherapy for osteoarthritis of the elbow or stifle in dogs in a randomized, double-blind, placebo-controlled, prospective pilot study. Seventeen dogs were evaluated with 10 meeting inclusion criteria for this study. Evaluations included orthopedic exam, visual lameness scoring, Canine Brief Pain Inventory (CBPI), goniometry, kinetic gait analysis, and radiography. Initial lameness score, age, body weight, duration of lameness, and CBPI scores did not differ between groups...
May 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28283074/vertical-force-distribution-in-the-paws-of-sound-labrador-retrievers-during-walking
#6
N Schwarz, A Tichy, C Peham, B Bockstahler
In contrast to gait analysis in humans, where pedobarography is an integral part of biomechanical studies, veterinary researchers have rarely investigated vertical force distribution (VFD) in the paws of dogs. The aim of this study was to investigate the VFD of peak of vertical force (PFz), vertical impulse (IFz) and time of occurrence of PFz during stance phase (TPFz) in 20 sound, adult Labrador retrievers walking normally on a pressure plate. A technique was used that divided the canine paw prints into quadrants...
March 2017: Veterinary Journal
https://www.readbyqxmd.com/read/27580105/effects-of-administration-of-adipose-derived-stromal-vascular-fraction-and-platelet-rich-plasma-to-dogs-with-osteoarthritis-of-the-hip-joints
#7
David A Upchurch, Walter C Renberg, James K Roush, George A Milliken, Mark L Weiss
OBJECTIVE To evaluate effects of simultaneous intra-articular and IV injection of autologous adipose-derived stromal vascular fraction (SVF) and platelet-rich plasma (PRP) to dogs with osteoarthritis of the hip joints. ANIMALS 22 client-owned dogs (12 placebo-treated [control] dogs and 10 treated dogs). PROCEDURES Dogs with osteoarthritis of the hip joints that caused signs of lameness or discomfort were characterized on the basis of results of orthopedic examination, goniometry, lameness score, the Canine Brief Pain Inventory (CBPI), a visual analogue scale, and results obtained by use of a pressure-sensing walkway at week 0 (baseline)...
September 2016: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/27493284/post-operative-complications-associated-with-the-arthrex-canine-cranial-cruciate-ligament-repair-anchor-system-in-small-to-medium-sized-dogs-a-retrospective-analysis-2009-2012
#8
Nick S Rappa, Robert M Radasch
This study classified and determined the post-operative complication rate associated with stabilization of cranial (CCL) ligament deficient stifles in small- to medium-sized dogs with the Arthrex Canine Cranial Cruciate Ligament Repair Anchor System (CCLRAS). Eighty-five medical records from 2009 to 2012 from 1 institution were evaluated. Complications were classified according to previously proposed definitions for orthopedic studies in veterinary medicine. Fifty-two owners were contacted by telephone at least 6 months after surgery and given a questionnaire to classify complications related to the implant...
August 2016: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
https://www.readbyqxmd.com/read/27304984/-leishmania-infantum-induced-bone-lesions-in-a-dog
#9
Felix Wallborn, Charlotte Söffler, Philipp Winkels, Marcus Hess, Peter Engelhardt
A 3-year-old Labrador Retriever originating from Spain was presented with a left-sided hind limb lameness for several months. The orthopedic examination revealed a pain response when palpating the left tarsal joint. Radiographic and computed tomographic studies showed polyostotic, aggressive osteolytic bone lesions with mild erosive arthritis. The diagnosis of canine leishmaniasis was confirmed by bone biopsy and the detection of the pathogen by PCR. Three weeks after initiation of therapy with allopurinol, the dog presented no signs of lameness...
August 17, 2016: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
https://www.readbyqxmd.com/read/27269707/a-prospective-randomized-double-blind-placebo-controlled-evaluation-of-the-effects-of-eicosapentaenoic-acid-and-docosahexaenoic-acid-on-the-clinical-signs-and-erythrocyte-membrane-polyunsaturated-fatty-acid-concentrations-in-dogs-with-osteoarthritis
#10
Stephen J Mehler, Lauren R May, Crystal King, William S Harris, Zubin Shah
BACKGROUND: Osteoarthritis (OA) in dogs is a prevalent and serious condition. The most common treatment for the clinical signs of OA in dogs is the administration of nonsteroidal antiiflammatory pharmaceuticals. Omega-3 (n-3) fatty acids have been shown to reduce the clinical signs of osteoarthritis in dogs. OBJECTIVE: The primary goals of this study were 1) to determine the effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on the clinical signs of OA in dogs, 2) to evaluate the effects of supplementation on the arachadonic acid (ARA)/ (EPA+DHA) algorithm and 3) to correlate alterations in the ARA/(EPA+DHA) with changes in the clinical signs of canine OA...
June 2016: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/27027838/biochemical-histologic-and-biomechanical-characterization-of-native-and-decellularized-flexor-tendon-specimens-harvested-from-the-pelvic-limbs-of-orthopedically-normal-dogs
#11
Daniel G Balogh, Jeffery J Biskup, M Gerard O'Sullivan, Ruth M Scott, Donna Groschen, Richard B Evans, Michael G Conzemius
OBJECTIVE: To evaluate the biochemical and biomechanical properties of native and decellularized superficial digital flexor tendons (SDFTs) and deep digital flexor tendons (DDFTs) harvested from the pelvic limbs of orthopedically normal dogs. SAMPLE: 22 commercially supplied tendon specimens (10 SDFT and 12 DDFT) harvested from the pelvic limbs of 13 canine cadavers. PROCEDURES: DNA, glycosaminoglycan, collagen, and protein content were measured to biochemically compare native and decellularized SDFT and DDFT specimens...
April 2016: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/26392889/canine-adipose-derived-stromal-cell-viability-following-exposure-to-synovial-fluid-from-osteoarthritic-joints
#12
Kristina M Kiefer, Timothy D O'Brien, Elizabeth G Pluhar, Michael Conzemius
INTRODUCTION: Stem cell therapy used in clinical application of osteoarthritis in veterinary medicine typically involves intra-articular injection of the cells, however the effect of an osteoarthritic environment on the fate of the cells has not been investigated. AIMS AND OBJECTIVES: Assess the viability of adipose derived stromal cells following exposure to osteoarthritic joint fluid. MATERIALS AND METHODS: Adipose derived stromal cells (ASCs) were derived from falciform adipose tissue of five adult dogs, and osteoarthritic synovial fluid (SF) was obtained from ten patients undergoing surgical intervention on orthopedic diseases with secondary osteoarthritis...
2015: Veterinary Record Open
https://www.readbyqxmd.com/read/26234043/-study-of-chondrocyte-proliferative-activity-in-the-canine-articular-cartilage-during-lengthening-of-the-adjacent-limb-segment
#13
T A Stupina, M M Shchudlo, N A Shchudlo
To assess the effect of orthopedic lengthening on proliferative activity of chondrocytes in the articular cartilage, dosed tibial lengthening by 28 mm was performed in 15 dogs at the rate of I mm/day divided into 4 sessions. Experiment time-points - 28 days of distraction, 30 days of fixation in the apparatus and 30 days after the apparatus removal. Methods of light microscopy of paraffin sections, immunohistochemistry, histomorphometry of semithin epoxide sections were used. At the end of distraction, the preferential concentration of Ki-67 marker was detected in the upper layers of the intermediate zone, while focal distribution was noted in the superficial and deep zones of articular cartilage of femoral condyles...
2015: Morfologi︠a︡
https://www.readbyqxmd.com/read/26119416/golden-retriever-cystic-uveal-disease-a-longitudinal-study-of-iridociliary-cysts-pigmentary-uveitis-and-pigmentary-cystic-glaucoma-over-a-decade-in-western-canada
#14
Vanessa L Holly, Lynne S Sandmeyer, Bianca S Bauer, Linda Verges, Bruce H Grahn
OBJECTIVES: To determine the incidence of iridociliary cysts, pigmentary uveitis (PU)/pigmentary cystic glaucoma (PCG) in golden retriever dogs in western Canada, the progression of iridociliary cysts to PU/PCG, and a mode of inheritance for this disorder. ANIMAL STUDIED: A total of 830 golden retriever dogs from Alberta, Saskatchewan, and Manitoba from 2004 to 2014 were studied. PROCEDURE: Data were compiled from Canine Eye Registry Foundation (CERF) or Orthopedic Foundation for Animals (OFA) records (n = 630) and clinical consultations (n = 200) for a retrospective assessment of iridociliary cysts, PU, and PCG...
May 2016: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/26114897/mechanical-testing-of-a-synthetic-canine-gastrocnemius-tendon-implant
#15
Mark A Morton, Richard G Whitelock, John F Innes
OBJECTIVE: To test a polyethylene terephthalate prosthesis (STIF, Chenove, France) for gastrocnemius tendon repair in dogs (cadaver model). STUDY DESIGN: In vitro mechanical study. ANIMALS: Pelvic limbs (n = 8) from 4 recently euthanatized adult dogs (weighing 30-45 kg). METHODS: Proximally the implant was sutured at the myotendinous junction of the gastrocnemius and distally secured in a 4.5 mm blind ending tunnel in the medullary cavity of the calcaneus using an interference screw (STIF, Chenove, France)...
July 2015: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/26100641/comparison-of-magnesium-alloys-and-poly-l-lactide-screws-as-degradable-implants-in-a-canine-fracture-model
#16
Eriko Marukawa, Masato Tamai, Yukinobu Takahashi, Ichiro Hatakeyama, Masaru Sato, Yusuke Higuchi, Hiroshi Kakidachi, Hirofumi Taniguchi, Takamitsu Sakamoto, Jun Honda, Ken Omura, Hiroyuki Harada
The aims of this study were to evaluate in vivo the biological responses to implants composed of biodegradable anodized WE43 (containing magnesium yttrium, rare earth elements and zirconium; Elektron SynerMag®) magnesium alloy, monolithic WE43 magnesium alloy and poly-l-lactic acid (PLLA), which are commonly used materials in clinic settings, and to evaluate the effectiveness of the materials as bone screws. The effectiveness of the magnesium alloy implants in osteosynthesis was evaluated using a bone fracture model involving the tibia of beagle dogs...
October 2016: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/26085530/surface-modification-with-chemically-modified-synovial-fluid-for-flexor-tendon-reconstruction-in-a-canine-model-in-vivo
#17
Xiaoxi Ji, Ramona L Reisdorf, Andrew R Thoreson, Lawrence R Berglund, Steven L Moran, Gregory D Jay, Kai-Nan An, Peter C Amadio, Chunfeng Zhao
BACKGROUND: Functional restoration is the major concern after flexor tendon reconstruction in the hand. The purpose of the present study was to investigate the effects of modifying the surface of extrasynovial tendon autografts with carbodiimide-derivatized synovial fluid with gelatin (cd-SF-G) on functional outcomes of flexor tendon reconstruction using a canine model. METHODS: The second and fifth flexor digitorum profundus tendons from eleven dogs were transected and repaired in zone II...
June 17, 2015: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/25910516/initial-evaluation-of-a-canine-stifle-arthrotomy-post-operative-pain-model
#18
RANDOMIZED CONTROLLED TRIAL
A Tomas, D Bledsoe, S Wall, G Davidson, B D X Lascelles
Most models of acute post-operative orthopedic pain involve the injection of a clinically irrelevant pro-inflammatory agent. The ideal model should, however, be clinically relevant and allow full functional recovery of enrolled animals after research is completed. This study explored the validity of a model employing arthrotomy and objectively measured limb use. Six purpose-bred Beagles underwent arthrotomies on each stifle with a washout period in between. Using a randomized crossover design, each dog received placebo and an extended-release buprenorphine (ER-Bup) preparation...
June 2015: Veterinary Journal
https://www.readbyqxmd.com/read/25899881/single-stage-bilateral-tibial-tuberosity-advancement-for-treatment-of-bilateral-canine-cranial-cruciate-ligament-deficiency
#19
J E Kiefer, A Langenbach, J Boim, S Gordon, D J Marcellin-Little
OBJECTIVE: To report complications in dogs with naturally occurring cranial cruciate ligament rupture following single-stage bilateral tibial tuberosity advancement (SS-BTTA) procedures, and to compare these complications to a population of dogs undergoing unilateral tibial tuberosity advancement (UTTA). METHODS: Medical records and radiographs of client-owned dogs treated with tibial tuberosity advancement between August 2008 and December 2011 were reviewed. Forty-four client-owned dogs with bilateral cranial cruciate ligament rupture that underwent SS-BTTA procedures and 82 client-owned dogs that underwent UTTA procedures were randomly selected from our hospital population...
2015: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/25874693/a-genetic-predictive-model-for-canine-hip-dysplasia-integration-of-genome-wide-association-study-gwas-and-candidate-gene-approaches
#20
Nerea Bartolomé, Sergi Segarra, Marta Artieda, Olga Francino, Elisenda Sánchez, Magdalena Szczypiorska, Joaquim Casellas, Diego Tejedor, Joaquín Cerdeira, Antonio Martínez, Alfonso Velasco, Armand Sánchez
Canine hip dysplasia is one of the most prevalent developmental orthopedic diseases in dogs worldwide. Unfortunately, the success of eradication programs against this disease based on radiographic diagnosis is low. Adding the use of diagnostic genetic tools to the current phenotype-based approach might be beneficial. The aim of this study was to develop a genetic prognostic test for early diagnosis of hip dysplasia in Labrador Retrievers. To develop our DNA test, 775 Labrador Retrievers were recruited. For each dog, a blood sample and a ventrodorsal hip radiograph were taken...
2015: PloS One
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