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Canine dog orthopedic

David A Upchurch, Walter C Renberg, James K Roush, George A Milliken, Mark L Weiss
OBJECTIVE To evaluate effects of simultaneous intra-articular and IV injection of autologous adipose-derived stromal vascular fraction (SVF) and platelet-rich plasma (PRP) to dogs with osteoarthritis of the hip joints. ANIMALS 22 client-owned dogs (12 placebo-treated [control] dogs and 10 treated dogs). PROCEDURES Dogs with osteoarthritis of the hip joints that caused signs of lameness or discomfort were characterized on the basis of results of orthopedic examination, goniometry, lameness score, the Canine Brief Pain Inventory (CBPI), a visual analogue scale, and results obtained by use of a pressure-sensing walkway at week 0 (baseline)...
September 2016: American Journal of Veterinary Research
Nick S Rappa, Robert M Radasch
This study classified and determined the post-operative complication rate associated with stabilization of cranial (CCL) ligament deficient stifles in small- to medium-sized dogs with the Arthrex Canine Cranial Cruciate Ligament Repair Anchor System (CCLRAS). Eighty-five medical records from 2009 to 2012 from 1 institution were evaluated. Complications were classified according to previously proposed definitions for orthopedic studies in veterinary medicine. Fifty-two owners were contacted by telephone at least 6 months after surgery and given a questionnaire to classify complications related to the implant...
August 2016: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
Felix Wallborn, Charlotte Söffler, Philipp Winkels, Marcus Hess, Peter Engelhardt
A 3-year-old Labrador Retriever originating from Spain was presented with a left-sided hind limb lameness for several months. The orthopedic examination revealed a pain response when palpating the left tarsal joint. Radiographic and computed tomographic studies showed polyostotic, aggressive osteolytic bone lesions with mild erosive arthritis. The diagnosis of canine leishmaniasis was confirmed by bone biopsy and the detection of the pathogen by PCR. Three weeks after initiation of therapy with allopurinol, the dog presented no signs of lameness...
August 17, 2016: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
Stephen J Mehler, Lauren R May, Crystal King, William S Harris, Zubin Shah
BACKGROUND: Osteoarthritis (OA) in dogs is a prevalent and serious condition. The most common treatment for the clinical signs of OA in dogs is the administration of nonsteroidal antiiflammatory pharmaceuticals. Omega-3 (n-3) fatty acids have been shown to reduce the clinical signs of osteoarthritis in dogs. OBJECTIVE: The primary goals of this study were 1) to determine the effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on the clinical signs of OA in dogs, 2) to evaluate the effects of supplementation on the arachadonic acid (ARA)/ (EPA+DHA) algorithm and 3) to correlate alterations in the ARA/(EPA+DHA) with changes in the clinical signs of canine OA...
June 2016: Prostaglandins, Leukotrienes, and Essential Fatty Acids
Daniel G Balogh, Jeffery J Biskup, M Gerard O'Sullivan, Ruth M Scott, Donna Groschen, Richard B Evans, Michael G Conzemius
OBJECTIVE: To evaluate the biochemical and biomechanical properties of native and decellularized superficial digital flexor tendons (SDFTs) and deep digital flexor tendons (DDFTs) harvested from the pelvic limbs of orthopedically normal dogs. SAMPLE: 22 commercially supplied tendon specimens (10 SDFT and 12 DDFT) harvested from the pelvic limbs of 13 canine cadavers. PROCEDURES: DNA, glycosaminoglycan, collagen, and protein content were measured to biochemically compare native and decellularized SDFT and DDFT specimens...
April 2016: American Journal of Veterinary Research
Kristina M Kiefer, Timothy D O'Brien, Elizabeth G Pluhar, Michael Conzemius
INTRODUCTION: Stem cell therapy used in clinical application of osteoarthritis in veterinary medicine typically involves intra-articular injection of the cells, however the effect of an osteoarthritic environment on the fate of the cells has not been investigated. AIMS AND OBJECTIVES: Assess the viability of adipose derived stromal cells following exposure to osteoarthritic joint fluid. MATERIALS AND METHODS: Adipose derived stromal cells (ASCs) were derived from falciform adipose tissue of five adult dogs, and osteoarthritic synovial fluid (SF) was obtained from ten patients undergoing surgical intervention on orthopedic diseases with secondary osteoarthritis...
2015: Veterinary Record Open
T A Stupina, M M Shchudlo, N A Shchudlo
To assess the effect of orthopedic lengthening on proliferative activity of chondrocytes in the articular cartilage, dosed tibial lengthening by 28 mm was performed in 15 dogs at the rate of I mm/day divided into 4 sessions. Experiment time-points - 28 days of distraction, 30 days of fixation in the apparatus and 30 days after the apparatus removal. Methods of light microscopy of paraffin sections, immunohistochemistry, histomorphometry of semithin epoxide sections were used. At the end of distraction, the preferential concentration of Ki-67 marker was detected in the upper layers of the intermediate zone, while focal distribution was noted in the superficial and deep zones of articular cartilage of femoral condyles...
2015: Morfologi︠a︡
Vanessa L Holly, Lynne S Sandmeyer, Bianca S Bauer, Linda Verges, Bruce H Grahn
OBJECTIVES: To determine the incidence of iridociliary cysts, pigmentary uveitis (PU)/pigmentary cystic glaucoma (PCG) in golden retriever dogs in western Canada, the progression of iridociliary cysts to PU/PCG, and a mode of inheritance for this disorder. ANIMAL STUDIED: A total of 830 golden retriever dogs from Alberta, Saskatchewan, and Manitoba from 2004 to 2014 were studied. PROCEDURE: Data were compiled from Canine Eye Registry Foundation (CERF) or Orthopedic Foundation for Animals (OFA) records (n = 630) and clinical consultations (n = 200) for a retrospective assessment of iridociliary cysts, PU, and PCG...
May 2016: Veterinary Ophthalmology
Mark A Morton, Richard G Whitelock, John F Innes
OBJECTIVE: To test a polyethylene terephthalate prosthesis (STIF, Chenove, France) for gastrocnemius tendon repair in dogs (cadaver model). STUDY DESIGN: In vitro mechanical study. ANIMALS: Pelvic limbs (n = 8) from 4 recently euthanatized adult dogs (weighing 30-45 kg). METHODS: Proximally the implant was sutured at the myotendinous junction of the gastrocnemius and distally secured in a 4.5 mm blind ending tunnel in the medullary cavity of the calcaneus using an interference screw (STIF, Chenove, France)...
July 2015: Veterinary Surgery: VS
Eriko Marukawa, Masato Tamai, Yukinobu Takahashi, Ichiro Hatakeyama, Masaru Sato, Yusuke Higuchi, Hiroshi Kakidachi, Hirofumi Taniguchi, Takamitsu Sakamoto, Jun Honda, Ken Omura, Hiroyuki Harada
The aims of this study were to evaluate in vivo the biological responses to implants composed of biodegradable anodized WE43 (containing magnesium yttrium, rare earth elements and zirconium; Elektron SynerMag®) magnesium alloy, monolithic WE43 magnesium alloy and poly-l-lactic acid (PLLA), which are commonly used materials in clinic settings, and to evaluate the effectiveness of the materials as bone screws. The effectiveness of the magnesium alloy implants in osteosynthesis was evaluated using a bone fracture model involving the tibia of beagle dogs...
October 2016: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Xiaoxi Ji, Ramona L Reisdorf, Andrew R Thoreson, Lawrence R Berglund, Steven L Moran, Gregory D Jay, Kai-Nan An, Peter C Amadio, Chunfeng Zhao
BACKGROUND: Functional restoration is the major concern after flexor tendon reconstruction in the hand. The purpose of the present study was to investigate the effects of modifying the surface of extrasynovial tendon autografts with carbodiimide-derivatized synovial fluid with gelatin (cd-SF-G) on functional outcomes of flexor tendon reconstruction using a canine model. METHODS: The second and fifth flexor digitorum profundus tendons from eleven dogs were transected and repaired in zone II...
June 17, 2015: Journal of Bone and Joint Surgery. American Volume
A Tomas, D Bledsoe, S Wall, G Davidson, B D X Lascelles
Most models of acute post-operative orthopedic pain involve the injection of a clinically irrelevant pro-inflammatory agent. The ideal model should, however, be clinically relevant and allow full functional recovery of enrolled animals after research is completed. This study explored the validity of a model employing arthrotomy and objectively measured limb use. Six purpose-bred Beagles underwent arthrotomies on each stifle with a washout period in between. Using a randomized crossover design, each dog received placebo and an extended-release buprenorphine (ER-Bup) preparation...
June 2015: Veterinary Journal
J E Kiefer, A Langenbach, J Boim, S Gordon, D J Marcellin-Little
OBJECTIVE: To report complications in dogs with naturally occurring cranial cruciate ligament rupture following single-stage bilateral tibial tuberosity advancement (SS-BTTA) procedures, and to compare these complications to a population of dogs undergoing unilateral tibial tuberosity advancement (UTTA). METHODS: Medical records and radiographs of client-owned dogs treated with tibial tuberosity advancement between August 2008 and December 2011 were reviewed. Forty-four client-owned dogs with bilateral cranial cruciate ligament rupture that underwent SS-BTTA procedures and 82 client-owned dogs that underwent UTTA procedures were randomly selected from our hospital population...
2015: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
Nerea Bartolomé, Sergi Segarra, Marta Artieda, Olga Francino, Elisenda Sánchez, Magdalena Szczypiorska, Joaquim Casellas, Diego Tejedor, Joaquín Cerdeira, Antonio Martínez, Alfonso Velasco, Armand Sánchez
Canine hip dysplasia is one of the most prevalent developmental orthopedic diseases in dogs worldwide. Unfortunately, the success of eradication programs against this disease based on radiographic diagnosis is low. Adding the use of diagnostic genetic tools to the current phenotype-based approach might be beneficial. The aim of this study was to develop a genetic prognostic test for early diagnosis of hip dysplasia in Labrador Retrievers. To develop our DNA test, 775 Labrador Retrievers were recruited. For each dog, a blood sample and a ventrodorsal hip radiograph were taken...
2015: PloS One
Jarrod R Troy, Mary Sarah Bergh
Canine cranial cruciate ligament rupture (CCLR) is the most common cause of pelvic limb lameness in dogs. CCLR results in palpable stifle instability secondary to cranial translation of the tibial relative to the femur, and it can be diagnosed during the orthopedic exam using the cranial drawer test (CDT) and tibial compression test (TCT). Accurate diagnosis of CCLR depends on the efficacy in performing these tests. In this study, two three-dimensional canine pelvic limb models were developed: one simulating a normal stifle and one simulating CCLR...
2015: Journal of Veterinary Medical Education
Miranda J Aiken, Thomas K Hughes, Ralph H Abercromby, Mark A Holmes, Angus A Anderson
OBJECTIVES: To determine whether extending prophylactic antimicrobial administration into the postoperative period would decrease the surgical site infection (SSI) rate in clean canine orthopedic surgery associated with a metal implant. STUDY DESIGN: Randomized prospective clinical study. SAMPLE POPULATION: Consecutive procedures (n = 400) on dogs that had clean orthopedic surgery using a metal implant. METHODS: Cases were randomly allocated to 1 of 2 groups...
July 2015: Veterinary Surgery: VS
Gregor Hauschild, Jendrik Hardes, Georg Gosheger, Sandra Stoeppeler, Helmut Ahrens, Franziska Blaske, Christoph Wehe, Uwe Karst, Steffen Höll
Infection associated with biomaterials used for orthopedic prostheses remains a serious complication in orthopedics, especially tumor surgery. Silver-coating of orthopedic (mega)prostheses proved its efficiency in reducing infections but has been limited to surface areas exposed to soft tissues due to concerns of silver inhibiting osseous integration of cementless stems. To close this gap in the bactericidal capacity of silver-coated orthopedic prostheses extension of the silver-coating on surface areas intended for osseous integration seems to be inevitable...
2015: BioMed Research International
Jingheng Wu, Andrew R Thoreson, Ramona L Reisdorf, Kai-Nan An, Steven L Moran, Peter C Amadio, Chunfeng Zhao
The purpose of this study was to investigate the biomechanical properties of modified repair techniques for flexor tendon reconstruction and the effects of surface modification using carbodiimide-derivatized synovial fluid plus gelatin (cd-SF-G), compared to the traditional repair techniques. The second and fifth digits from 16 canine forepaws were randomly divided into 4 groups: (1) traditional graft repairs (TGR group) including distal Bunnell repair and proximal Pulvertaft weave repair; (2) modified graft repairs (MGR group) including distal graft bony attachment repair and proximal step-cut repair; (3) group TGR coated with cd-SF-G (TGR-C group); and (4) group MGR coated with cd-SF-G (MGR-C group)...
May 2015: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
Susanne M Stieger-Vanegas, Sri Kumar Jamie Senthirajah, Sarah Nemanic, Wendy Baltzer, Jennifer Warnock, Katelyn Hollars, Scott S Lee, Gerd Bobe
OBJECTIVE: To determine, using 3 groups of evaluators of varying experience reading orthopedic CT studies, if 3-dimensional computed tomography (3D-CT) provides a more accurate and time efficient method for diagnosis of canine sacral and pelvic fractures, and displacements of the sacroiliac and coxofemoral joints compared with 2-dimensional computed tomography (2D-CT). STUDY DESIGN: Retrospective clinical and prospective study. ANIMALS: Dogs (n = 23): 12 dogs with traumatic pelvic fractures, 11 canine cadavers with pelvic trauma induced by a lateral impactor...
August 2015: Veterinary Surgery: VS
Darryl L Millis, Ionut Alexandru Ciuperca
This article reviews some important studies regarding canine physical rehabilitation. Bones, cartilage, muscles, ligaments, and tendons undergo atrophy if loading is decreased. Knowledge of the changes that occur with immobilization and the time course of events helps in the development of a rehabilitation program to improve tissue integrity. Outcome assessment instruments are clinically useful indicators of patient progress and the success of rehabilitation programs. A number of physical modalities are used in canine rehabilitation, although there are relatively few canine-specific studies...
January 2015: Veterinary Clinics of North America. Small Animal Practice
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