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https://www.readbyqxmd.com/read/28212289/the-effects-of-myo-inositol-and-b-and-d-vitamin-supplementation-in-the-db-mouse-model-of-gestational-diabetes-mellitus
#1
Jasmine F Plows, Florence Budin, Rebecka A M Andersson, Valerie J Mills, Katherine Mace, Sandra T Davidge, Mark H Vickers, Philip N Baker, Irma Silva-Zolezzi, Joanna L Stanley
Gestational diabetes mellitus (GDM) is a growing concern, affecting an increasing number of pregnant women worldwide. By predisposing both the affected mothers and children to future disease, GDM contributes to an intergenerational cycle of obesity and diabetes. In order to stop this cycle, safe and effective treatments for GDM are required. This study sought to determine the treatment effects of dietary supplementation with myo-inositol (MI) and vitamins B2, B6, B12, and D in a mouse model of GDM (pregnant db/+ dams)...
February 15, 2017: Nutrients
https://www.readbyqxmd.com/read/28210447/the-effect-of-different-insertion-techniques-on-the-depth-of-cure-and-vickers-surface-micro-hardness-of-two-bulk-fill-resin-composite-materials
#2
Lamiaa-Mahmoud Moharam, Ahmed-Zohair El-Hoshy, Karim Abou-Elenein
BACKGROUND: The aim of this study was to evaluate the Vickers surface micro-hardness and the depth of cure of two bulk-fill resin composites and one incremental-fill resin composite. MATERIAL AND METHODS: Two Bulk-fill dental resin composites (X-tra Fil, Voco; Sonic-FillTM 2, Kerr Corporation) and an incremental-fill dental resin composite (Filtek™ Z250 XT, 3M ESPE) were used. Sixty cylindrical specimens of 4 mm thickness were prepared using split Teflon moulds...
February 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28210444/effect-of-two-different-tooth-bleaching-techniques-on-microhardness-of-giomer
#3
Soodabeh Kimyai, Mahmoud Bahari, Fereshteh Naser-Alavi, Soodabeh Behboodi
BACKGROUND: Tooth bleaching is a safe and conservative treatment modality to improve the esthetic appearance of discolored teeth. One of the problems with the use of bleaching agents is their possible effect on surface microhardness of resin-based materials. The present study was carried out to evaluate the effect of in-office and at-home bleaching on surface microhardness of giomer. MATERIAL AND METHODS: Seventy-five disk-shaped giomer samples (Beautifil II) were prepared and cured with a light-curing unit...
February 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28199178/response-to-comment-on-decisional-conflict-regret-and-the-burden-of-rational-decision-making
#4
Andrew Vickers
No abstract text is available yet for this article.
February 1, 2017: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/28188187/electronic-rapid-fitness-assessment-a-novel-tool-for-preoperative-evaluation-of-the-geriatric-oncology-patient
#5
Armin Shahrokni, Amy Tin, Robert J Downey, Vivian Strong, Sanam Mahmoudzadeh, Manpreet K Boparai, Sincere McMillan, Andrew Vickers, Beatriz Korc-Grodzicki
Background: The American College of Surgeons and American Geriatrics Society recommend performing a geriatric assessment (GA) in the preoperative evaluation of older patients. To address this, we developed an electronic GA, the Electronic Rapid Fitness Assessment (eRFA). We reviewed the feasibility and clinical utility of the eRFA in the preoperative evaluation of geriatric patients. Methods: We performed a retrospective review of our experience using the eRFA in the preoperative assessment of geriatric patients...
February 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/28187138/a-randomized-controlled-trial-of-a-group-based-gaze-training-intervention-for-children-with-developmental-coordination-disorder
#6
Greg Wood, Charlotte A L Miles, Ginny Coyles, Omid Alizadehkhaiyat, Samuel J Vine, Joan N Vickers, Mark R Wilson
: The aim of this study was to integrate a gaze training intervention (i.e., quiet eye training; QET) that has been shown to improve the throwing and catching skill of children with Developmental Coordination Disorder (DCD), within an approach (i.e., group therapy) that might alleviate the negative psychosocial impact of these motor skill deficits. Twenty-one children with DCD were split into either QET (8 male 3 female, mean age of 8.6 years (SD = 1.04) or technical training (TT) groups (7 male 3 female, mean age of 8...
2017: PloS One
https://www.readbyqxmd.com/read/28183738/reply-to-letter-to-the-editor-determining-the-potential-effects-of-oxidized-fish-oils-in-pregnant-women-requires-a-more-systematic-approach
#7
Benjamin B Albert, José G B Derraik, Mark H Vickers, Manohar L Garg, David Cameron-Smith, Paul L Hofman, Wayne S Cutfield
No abstract text is available yet for this article.
February 1, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28183676/tizrnbtamo-high-entropy-alloy-designed-for-orthopedic-implants-as-cast-microstructure-and-mechanical-properties
#8
Shao-Ping Wang, Jian Xu
Combining the high-entropy alloy (HEA) concept with property requirement for orthopedic implants, we designed a Ti20Zr20Nb20Ta20Mo20 equiatomic HEA. The arc-melted microstructures, compressive properties and potentiodynamic polarization behavior in phosphate buffer solution (PBS) were studied in detail. It was revealed that the as-cast TiZrNbTaMo HEA consisted of dual phases with bcc structure, major bcc1 and minor bcc2 phases with the lattice parameters of 0.3310nm and 0.3379nm, respectively. As confirmed by nanoindentation tests, the bcc1 phase is somewhat harder and stiffer than the bcc2 phase...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28183068/electroless-deposition-of-nickel-boron-coatings-using-low-frequency-ultrasonic-agitation-effect-of-ultrasonic-frequency-on-the-coatings
#9
L Bonin, N Bains, V Vitry, A J Cobley
The effect of ultrasound on the properties of Nickel-Boron (NiB) coatings was investigated. NiB coatings were fabricated by electroless deposition using either ultrasonic or mechanical agitation. The deposition of Ni occurred in an aqueous bath containing a reducible metal salt (nickel chloride), reducing agent (sodium borohydride), complexing agent (ethylenediamine) and stabilizer (lead tungstate). Due to the instability of the borohydride in acidic, neutral and slightly alkaline media, pH was controlled at pH 12±1 in order to avoid destabilizing the bath...
January 30, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28174008/setting-characteristics-and-mechanical-properties-of-self-adhesive-resin-luting-agents
#10
Raphael Pilo, Dimitris Papadogiannis, Spiros Zinelis, George Eliades
OBJECTIVE: To evaluate the degree of conversion (DC%), salt yield and mechanical properties of self-adhesive luting agents (SAA) set under dual-cure (E) and self-cure (NE) modes. METHODS: Three SAA (GC LinkAce/GCLA, MaxCem Elite/MXEL, Rely-X Unicem 2/RXUN) and an adhesive resin luting agent (Rely-X Ultimate/RXUL-control) were used. The properties tested under E and NE modes were a) DC% and phosphate salt yield after 10min, 1h (h) and 3 weeks (w) storage, by infrared spectroscopy; and b) the mechanical properties of 3w-stored specimens by instrumented indentation testing (Martens hardness/HM, Elastic modulus/EIT, Elastic index/ηIT) and microscopic Vickers hardness/VH...
February 4, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28165743/design-and-synthesis-of-novel-and-selective-phosphodiesterase-2-pde2-inhibitors-for-the-treatment-of-memory-disorders
#11
Laurent Gomez, Mark Eben Massari, Troy Vickers, Graeme Freestone, William F Vernier, Kiev Ly, Rui Xu, Margaret McCarrick, Tami Marrone, Markus Metz, Yingzhou G Yan, Zachary W Yoder, Robert Lemus, Nicola J Broadbent, Richard Barido, Noelle Warren, Kara Schmelzer, David Neul, Dong Lee, Carsten B Andersen, Kristen Sebring, Kathleen Aertgeerts, Xianbo Zhou, Ali Tabatabaei, Marco Peters, J Guy Breitenbucher
A series of potent and selective [1,2,4]triazolo[1,5-a]pyrimidine PDE2 inhibitors is reported. The design and improvement of the binding properties of this series was achieved using X-ray crystal structures in conjunction with careful analysis of electronic and structural requirements for the PDE2a enzyme. One of the lead compounds, compound 27 (DNS-8254), was identified as a potent and highly selective PDE2a enzyme inhibitor with favorable rat pharmacokinetic properties. Interestingly, increased potency of compound 27 was facilitated by the formation of a halogen bond with the oxygen of Tyr827 present in the PDE2 active site...
February 6, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28164262/brief-communication-correlation-between-elastic-modulus-and-radiographic-density-in-mandibular-cortical-bone-of-colobine-monkeys
#12
Andrew J Rapoff, W Scott McGraw, Ana Duque, David J Daegling
OBJECTIVES: The relationship between radiographic grayscale and elastic modulus was determined using mandibular cortical bone of colobine monkeys. Quantification of this relationship is critical for establishing absolute measures of structural rigidity of skeletal elements. MATERIALS AND METHODS: We determined the Vickers microhardness values in mandibular bone from two species of African colobine monkeys and related these values to elastic modulus through an empirically determined correlation...
February 6, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28162971/comparison-of-friction-forces-between-stainless-orthodontic-steel-brackets-and-tini-wires-in-wet-and-dry-conditions
#13
Aphinan Phukaoluan, Anak Khantachawana, Pongpan Kaewtatip, Surachai Dechkunakorn, Niwat Anuwongnukroh, Peerapong Santiwong, Julathep Kajornchaiyakul
In sliding mechanics, frictional force is an important counter-balancing element to orthodontic tooth movement, which must be controlled in order to allow application of light continuous forces. The purpose of this study was to compare the frictional forces between a stainless steel bracket and five different wire alloys under dry and wet (artificial saliva) conditions. TiNi, TiNiCu, TiNiCo, commercial wires A and commercial wires B with equal dimensions of 0.016×0.022'' were tested in this experiment. The stainless steel bracket was chosen with a slot dimension of 0...
February 2, 2017: International Orthodontics
https://www.readbyqxmd.com/read/28158732/in-vitro-activity-of-cefepime-zidebactam-wck-5222-against-gram-negative-bacteria
#14
David M Livermore, Shazad Mushtaq, Marina Warner, Anna Vickers, Neil Woodford
No abstract text is available yet for this article.
February 3, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28152274/fe-3-seo42-dual-doped-nano-hydroxyapatite-a-novel-material-for-biomedical-applications
#15
Ammar Z Alshemary, Ahmet Engin Pazarceviren, Aysen Tezcaner, Zafer Evis
Dual ions substituted hydroxyapatite (HA) received attention from scientists and researchers in the biomedical field owing to their excellent biological properties. This paper presents a novel biomaterial, which holds potential for bone tissue applications. Herein, we have successfully incorporated ferric (Fe(3+) )/selenate (SeO42-) ions into the HA structure (Ca10-x-y Fey (PO4 )6-x (SeO4 )x (OH)2-x-y Oy ) (Fe-SeHA) through a microwave refluxing process. The Fe-SeHA materials were characterized by X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, and field emission scanning electron microscopy (FESEM)...
February 2, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28135118/ebola-virus-and-marburg-virus-in-human-milk-are-inactivated-by-holder-pasteurization
#16
Erin Hamilton Spence, Monica Huff, Karen Shattuck, Amy Vickers, Nadezda Yun, Slobodan Paessler
BACKGROUND: Potential donors of human milk are screened for Ebola virus (EBOV) using standard questions, but testing for EBOV and Marburg virus (MARV) is not part of routine serological testing performed by milk banks. Research aim: This study tested the hypothesis that EBOV would be inactivated in donor human milk (DHM) by standard pasteurization techniques (Holder) used in all North American nonprofit milk banks. METHODS: Milk samples were obtained from a nonprofit milk bank...
January 1, 2017: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/28132390/impact-of-self-reported-data-on-the-acquisition-of-multi-generational-family-history-and-lifestyle-factors-among-women-seen-in-a-high-risk-breast-screening-program-a-focus-on-modifiable-risk-factors-and-genetic-referral
#17
Laura H Rosenberger, Ryan Weber, Daniel Sjoberg, Andrew J Vickers, Debra A Mangino, Monica Morrow, Melissa L Pilewskie
BACKGROUND: The phrase "high-risk for breast cancer" is used to identify various groups at elevated cancer risk, and the appropriate surveillance and risk-reducing strategies differ based on the etiology of risk. Here, we review the utility of patient-reported data to capture women with modifiable lifestyle risk factors and those suitable for genetic counseling referral. METHODS: Patient-reported data from a web-based survey were used to capture personal history, multi-generational family history, and lifestyle factors (body mass index, alcohol consumption, physical activity)...
January 28, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28131415/blue-thermomechanical-treatment-optimizes-fatigue-resistance-and-flexibility-of-the-reciproc-files
#18
Gustavo De-Deus, Emmanuel João Nogueira Leal Silva, Victor Talarico Leal Vieira, Felipe Gonçalves Belladonna, Carlos Nelson Elias, Gianluca Plotino, Nicola Maria Grande
INTRODUCTION: The aim of the present study was to evaluate the influence of Blue thermal treatment on the bending resistance and cyclic fatigue of conventional M-Wire Reciproc files (VDW, Munich, Germany). The roughness pattern and the microhardness of the files were also assessed. METHODS: Flexibility of standard Reciproc R25 files and the corresponding Blue prototypes was determined by 45° bending tests according to the ISO 3630-1 specification. Instruments were also subjected to cyclic fatigue resistance, measuring the time to fracture in an artificial stainless steel canal with a 60° angle and a 5-mm radius of curvature...
January 25, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28129893/a-systematic-approach-to-discussing-active-surveillance-with-patients-with-low-risk-prostate-cancer
#19
Behfar Ehdaie, Melissa Assel, Nicole Benfante, Deepak Malhotra, Andrew Vickers
BACKGROUND: Physicians report difficulty convincing patients with prostate cancer about the merits of active surveillance (AS); as a result, a majority of patients unnecessarily choose to undergo radical treatment. OBJECTIVE: To develop and evaluate a systematic approach for physicians to counsel patients with low-risk prostate cancer to increase acceptance of AS. DESIGN, SETTING, AND PARTICIPANTS: A systematic counseling approach was developed and piloted in one clinic...
January 24, 2017: European Urology
https://www.readbyqxmd.com/read/28129527/decision-curves-calibration-and-subgroups
#20
Andrew J Vickers, Ben Van Calster, Ewout Steyerberg
No abstract text is available yet for this article.
February 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
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