keyword
MENU ▼
Read by QxMD icon Read
search

Paired associates

keyword
https://www.readbyqxmd.com/read/28945045/-real-world-analysis-to-explore-clinical-features-of-shenxiong-glucose-injection-combined-with-other-medications
#1
Gui-Qian Wang, Yan-Ming Xie, Huan Liu, Yin Zhang, Ping-Ping Jia, Yan Zhuang
To explore the real world clinical medication and combination characteristics of Shenxiong glucose injection. The basic information of patients with Shenxiong glucose injection, traditional Chinese and western medicine diagnosis information, doctor advice information and laboratory test information from the hospital information system(HIS) of 19 tertiary hospitals in China. Apriori algorithm was adopted to establish the models, and Clementine 12.0 was used for correlation analysis to analyze the real world clinical medication and combination characteristics of Shenxiong glucose injection...
January 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28944858/decreased-expression-of-hsa%C3%A2-mir%C3%A2-372-predicts-poor-prognosis-in-patients-with-gallbladder-cancer-by-affecting-chloride-intracellular-channel-1
#2
Ning Zhou, Wei Cheng, Chuang Peng, Yi Liu, Bo Jiang
It has been reported that hsa‑microRNA (miRNA/miR)‑372 functions as a tumor suppressor or oncogene in various digestive system tumors, however, its roles in gallbladder cancer (GBC) are yet to be established. The present study aimed to determine the expression and clinical relevance of hsa‑miR‑372 in GBC. The expression of hsa‑miR‑372 in 80 pairs of human GBC tissues and adjacent normal gallbladder tissues was measured by reverse transcription‑quantitative polymerase chain reaction. Subsequently, the associations between hsa‑miR‑372 expression levels and the clinicopathological characteristics of patients with GBC were determined using χ2 test...
September 19, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944830/application-of-the-amniotic-fluid-metabolome-to-the-study-of-fetal-malformations-using-down-syndrome-as-a-specific-model
#3
Jun Huang, Jinhua Mo, Guili Zhao, Qiyin Lin, Guanhui Wei, Weinan Deng, Dunjin Chen, Bolan Yu
Although monitoring and diagnosis of fetal diseases in utero remains a challenge, metabolomics may provide an additional tool to study the etiology and pathophysiology of fetal diseases at a functional level. In order to explore specific markers of fetal disease, metabolites were analyzed in two separate sets of experiments using amniotic fluid from fetuses with Down syndrome (DS) as a model. Both sets included 10‑15 pairs of controls and cases, and amniotic fluid samples were processed separately; metabolomic fingerprinting was then conducted using UPLC‑MS...
September 18, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28944755/the-intriguing-effect-of-delay-time-to-sentinel-lymph-node-biopsy-on-survival-a-propensity-score-matching-study-on-a-cohort-of-melanoma-patients
#4
Antonio Tejera-Vaquerizo, Miguel Angel Descalzo-Gallego, Victor Traves, Celia Requena, Isidro Bolumar, Angel Pla, Eduardo Nagore
BACKGROUND: Time between primary melanoma excision and sentinel lymph node biopsy (SLNB) has not been sufficiently studied as an independent predictor of survival in cutaneous melanoma. OBJECTIVES: We used propensity score matching to evaluate whether early SLNB (performed ≤40 days from excisional biopsy) is associated with higher mortality in patients with cutaneous melanoma. MATERIALS & METHODS: A retrospective cohort study at a tertiary melanoma referral centre...
September 23, 2017: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/28944598/dentition-status-and-frailty-in-community-dwelling-older-adults-a-5-year-prospective-cohort-study
#5
Masanori Iwasaki, Akihiro Yoshihara, Misuzu Sato, Kumiko Minagawa, Mieko Shimada, Mamoru Nishimuta, Toshihiro Ansai, Yutaka Yoshitake, Hideo Miyazaki
AIM: To examine the longitudinal association between dentition status and incidence of frailty in older adults. METHODS: The present prospective cohort study included community-dwelling Japanese adults aged 75 years at baseline (n = 322). Dental examinations, biochemical blood examinations, physical performance and anthropometric measurements, and structured questionnaires were carried out at baseline. The presence of ≥20 teeth with nine or more occluding pairs of teeth was defined as functional dentition...
September 24, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28943993/effectiveness-of-a-glycylcycline-antibiotic-for-reducing-the-pathogenicity-of-superantigen-producing-methicillin-resistant-staphylococcus-aureus-in-burn-wounds
#6
Lauren B Nosanov, Daniel Y Jo, Pranay R Randad, Lauren T Moffatt, Bonnie C Carney, Rachel T Ortiz, Jeffrey W Shupp
Objective: Burn-injured patients are highly susceptible to infectious complications, which are often associated with increased morbidity and mortality. Rates of antibiotic resistance have increased, and resistant species such as methicillin-resistant Staphylococcus aureus provide additional challenges in the form of virulence factors. Proteins can disrupt local healing, leading to systemic immune disruption. To optimize outcomes, treatments that reduce pathogenicity must be identified. This study aims to compare a glycylcycline antibiotic-tigecycline-with clindamycin for effectiveness in treating superantigenic methicillin-resistant Staphylococcus aureus in burn wounds...
2017: Eplasty
https://www.readbyqxmd.com/read/28943935/identification-of-key-genes-associated-with-the-effect-of-osmotic-stimuli-on-intervertebral-discs-using-microarray-analysis
#7
Guangxiao Ni, Guobin Liu, Kunlun Yu
The present study aimed to explore the effect of osmotic stimuli on intervertebral discs (IVDs) using microarray analysis. Gene expression dataset GSE1648 was downloaded from the Gene Expression Omnibus database. There were 11 IVD cell samples in this dataset, which included 4 hyperosmotic stimuli samples, 3 hypoosmotic stimuli samples and 4 isosmotic stimuli samples. The differentially expressed genes (DEGs) in hyperosmotic or hypoosmotic IVD cells (designated DEGs-hyper or DEGs-hypo) were identified, compared with isosmotic cells, using the limma package of R software...
October 2017: Oncology Letters
https://www.readbyqxmd.com/read/28943858/effects-of-sleep-on-word-pair-memory-in-children-separating-item-and-source-memory-aspects
#8
Jing-Yi Wang, Frederik D Weber, Katharina Zinke, Hannes Noack, Jan Born
Word paired-associate learning is a well-established task to demonstrate sleep-dependent memory consolidation in adults as well as children. Sleep has also been proposed to benefit episodic features of memory, i.e., a memory for an event (item) bound into the spatiotemporal context it has been experienced in (source). We aimed to explore if sleep enhances word pair memory in children by strengthening the episodic features of the memory, in particular. Sixty-one children (8-12 years) studied two lists of word pairs with 1 h in between...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28943744/outpatient-treatment-based-on-self-management-strategies-for-chronic-drooling-in-two-children
#9
Tessa W P de Bruijn, Jody Sohier, Jan J W van der Burg
Drooling is a distressing condition, which is often caused by reduced oral motor control associated with a neurological disorder. It has significant medical, practical and psychosocial impact on children or youth and their families. Therefore, treatment is necessary. Although behavioural therapy for drooling shows promising results, it is generally time- and cost-intensive. For this reason, alternative ways to provide behavioural treatment for chronic drooling need to be explored. In a pair of case studies, the feasibility and potential of an outpatient variant of a behavioural treatment programme for drooling based on self-management strategies was researched with two children with oral motor difficulties...
2017: Journal of Developmental and Physical Disabilities
https://www.readbyqxmd.com/read/28943297/transcriptome-analysis-of-kuruma-shrimp-marsupenaeus-japonicus-hepatopancreas-in-response-to-white-spot-syndrome-virus-wssv-under-experimental-infection
#10
Shengping Zhong, Yong Mao, Jun Wang, Min Liu, Man Zhang, Yongquan Su
Kuruma shrimp (Marsupenaeus japonicus) is one of the most valuable crustacean species in capture fisheries and mariculture in the Indo-West Pacific. White spot syndrome virus (WSSV) is a highly virulent pathogen which has seriously threatened Kuruma shrimp aquaculture sector. However, little information is available in relation to underlying mechanisms of host-virus interaction in Kuruma shrimp. In this study, we performed a transcriptome analysis from the hepatopancreas of Kuruma shrimp challenged by WSSV, using Illumina-based RNA-Seq...
September 21, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28943200/determinants-of-the-overuse-of-imaging-in-low-risk-prostate-cancer-a-systematic-review
#11
REVIEW
Allison H Oakes, Ritu Sharma, Madeline Jackson, Jodi B Segal
BACKGROUND: The overuse of radiologic services, where imaging tests are provided in circumstances where the propensity for harm exceeds the propensity for benefit, comprises a risk to patient safety and a burden on health care systems. Advanced imaging in the staging of low-risk prostate cancer is considered an overused procedure by many professional societies, yet the determinants that drive this phenomenon are not fully appreciated. METHODS: We systematically searched published literature within MEDLINE and Embase from January 1998 to March 2017...
September 21, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28943102/hypothalamic-pathways-regulate-the-anorectic-action-of-p-chloro-diphenyl-diselenide-in-rats
#12
Cristiani F Bortolatto, Cristina W Nogueira, Begoña Porteiro, Mónica Imbernón, Ruben Nogueiras
Behavioral studies have suggested that (p-ClPhSe)2 elicits an anorectic-like action in rats by inducing multiple effects such as satiety-enhancing effect, malaise and specific flavor; however, the molecular mechanisms underlying its anorexigenic action remain unclarified. Here, male Sprague-Dawley rats received acute and sub-chronic intraperitoneal treatments with (p-ClPhSe)2; thereafter, in vivo and ex vivo analyses were carried out. The present study reveals that the reduction of food intake resulting from a single treatment with (p-ClPhSe)2 (1mg/kg, i...
September 21, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28943004/importance-of-postprocedural-wound-ischemia-and-foot-infection-wifi-restaging-in-predicting-limb-salvage
#13
Charles Leithead, Zdenek Novak, Emily Spangler, Marc A Passman, Adam Witcher, Mark A Patterson, Adam W Beck, Benjamin J Pearce
OBJECTIVE: The Wound, Ischemia, and foot Infection (WIfI) classification system was created to encompass demographic changes and expanding techniques of revascularization to perform meaningful analyses of outcomes in the treatment of the threatened limb. The WIfI index is intended to be analogous to the TNM staging system for cancer, with restaging to be done after control of infection and after revascularization. Our goal was to evaluate the effectiveness of WIfI restaging after therapy in the prediction of limb outcomes...
September 21, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28942968/survival-and-long-term-outcomes-after-mitral-valve-replacement-in-patients-aged-18-to-50%C3%A2-years
#14
Samuel R Schnittman, Shinobu Itagaki, Nana Toyoda, David H Adams, Natalia N Egorova, Joanna Chikwe
OBJECTIVE: To provide long-term data on survival and major morbidity after mitral valve replacement in patients aged 18 to 50 years. METHODS: Retrospective analysis of 2727 patients aged 18 to 50 years who underwent isolated mitral replacement in California and New York from 1997 to 2006. Median follow-up time was 12.4 years (maximum 15.0 years). The primary endpoint was mortality; secondary endopoints were stroke, major bleeding, and reoperation. Propensity matching yielded 373 patient pairs...
August 24, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28942954/serum-brain-derived-neurotrophic-factor-levels-in-subjects-with-major-depressive-disorder-with-previous-suicide-attempt-a-population-based-study
#15
Fernanda Pedrotti Moreira, Cristiane Jackson Borges, Carolina David Wiener, Paula Moraes da Silva, Luis Valmor Portela, Diogo R Lara, Ricardo Azevedo da Silva, Luciano Dias de Mattos Souza, Karen Jansen, Jean Pierre Oses
Major depressive disorders (MDD) and suicide are significant public health concerns. Recent studies have been demonstrated that alterations in Brain Derived Neurotrophic Factor (BDNF) can be associated with this psychiatric disorders, MDD and suicide. Thus, the aim of this study was to evaluate differences in serum levels in individuals with MDD and with or without suicide attempt (SA), from a population-based sample. This was a paired cross-sectional study nested in a population-based study. The psychopathology screen was performed with the Mini-International Neuropsychiatric Interview (MINI)...
September 14, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28942446/status-of-vitamin-a-and-related-compounds-and-clinical-outcomes-in-maternal-infant-pairs-in-the-midwestern-united-states
#16
Corrine Hanson, Marina Schumacher, Elizabeth Lyden, Jeremy Furtado, Matthew Van Ormer, Elizabeth McGinn, Katherine Rilett, Caleb Cave, Rebecca Johnson, Kara Weishaar, Ann Anderson-Berry
BACKGROUND: Vitamin A is an essential nutrient for pregnant women, and other vitamin A-related compounds, including lutein and lycopene, have been associated with maternal-infant outcomes. The objective of this study was to quantify the status of vitamin A and related compounds in maternal-infant pairs at the time of delivery, and to determine its impact on clinical outcomes. METHODS: Maternal and cord blood samples were collected in 189 mother-infant pairs. Concentrations of lutein + zeaxanthin, β-cryptoxanthin, lycopene, carotenes, and retinol were measured using high-performance liquid chromatography...
September 22, 2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28942442/evolutionary-relationships-among-boulengerella-species-ctenoluciidae-characiformes-genomic-organization-of-repetitive-dnas-and-highly-conserved-karyotypes
#17
José F de Souza E Sousa, Patrik F Viana, Luiz A C Bertollo, Marcelo B Cioffi, Eliana Feldberg
Ctenoluciidae is a Neotropical freshwater fish family whose representatives are known as bicudas. The genus Boulengerella contains 5 species, and 4 of them (B. cuvieri, B. lateristriga, B. lucius, and B. maculata) were cytogenetically analyzed in the present study by conventional and molecular procedures. All 4 species have a very similar karyotype, with 2n = 36 chromosomes (14 metacentrics + 16 submetacentrics + 6 subtelocentrics; FN = 72). However, the heterochromatin distribution pattern is species-specific...
September 23, 2017: Cytogenetic and Genome Research
https://www.readbyqxmd.com/read/28941795/avoiding-escalation-from-play-to-aggression-in-adult-male-rats-the-role-of-ultrasonic-calls
#18
Candace J Burke, Theresa M Kisko, Sergio M Pellis, David R Euston
Play fighting is most commonly associated with juvenile animals, but in some species, including rats, it can continue into adulthood. Post-pubertal engagement in play fighting is often rougher and has an increased chance of escalation to aggression, making the use of play signals to regulate the encounter more critical. During play, both juvenile and adult rats emit many 50-kHz calls and some of these may function as play facilitating signals. In the present study, unfamiliar adult male rats were introduced in a neutral enclosure and their social interactions were recorded...
September 20, 2017: Behavioural Processes
https://www.readbyqxmd.com/read/28941767/a-proton-mr-spectroscopy-study-of-the-thalamus-in-twins-with-autism-spectrum-disorder
#19
John P Hegarty, Meng Gu, Daniel M Spielman, Sue C Cleveland, Joachim F Hallmayer, Laura C Lazzeroni, Mira M Raman, Thomas W Frazier, Jennifer M Phillips, Allan L Reiss, Antonio Y Hardan
Multiple lines of research have reported thalamic abnormalities in individuals with autism spectrum disorder (ASD) that are associated with social communication impairments (SCI), restricted and repetitive behaviors (RRB), or sensory processing abnormalities (SPA). Thus, the thalamus may represent a common neurobiological structure that is shared across symptom domains in ASD. Same-sex monozygotic (MZ) and dizygotic (DZ) twin pairs with and without ASD underwent cognitive/behavioral evaluation and magnetic resonance imaging to assess the thalamus...
September 20, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28941723/aeg-1-mrna-expression-in-non-small-cell-lung-cancer-is-associated-with-increased-tumor-angiogenesis
#20
Zhihong Ma, Yingrong Chen, Shunli Dong, Xuting Xu, Jin Liu, Pengtao Song, Caihua Yu, Licheng Dai
Astrocyte-elevated gene-1 (AEG-1) is implicated in the oncogenesis and angiogenesis of various types of human malignant disease. However, the angiogenesis roles of AEG-1 in non-small cell lung cancer (NSCLC) remain to be further elucidated. In the present study, the expression level of AEG-1 mRNA in seven human lung cell lines and 89 paired tissue samples (tumor tissues (TTs) and pair-matched normal adjacent tissues (PMNATs)) from NSCLC patients was detected by real-time PCR. Staining of vascular endothelial growth factor (VEGF) and intratumoral microvessel density (iMVD, labeled by CD105) were assessed by immunohistochemistry...
September 7, 2017: Pathology, Research and Practice
keyword
keyword
116447
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"