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https://www.readbyqxmd.com/read/28332404/conceptual-design-and-implantation-of-an-external-fixator-with-improved-mobility-for-knee-rehabilitation
#1
Gianluca Gatti
A hinged external fixator is used to allow early knee rehabilitation in case of injury or trauma, as an alternative approach to immobilization. It is mainly adopted for the treatment of dislocations, which involve tearing of the ligaments, and it basically consists of two links connected to each other by a revolute joint. Each link is fixed to the femur and tibia via pin fixation, and the revolute joint is approximately aligned to the knee flexion-extension (FE) axis. The advantage in its implantation is to protect ligament reconstruction, while allowing for an aggressive rehabilitation...
March 23, 2017: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/28294580/effect-of-cerebrospinal-fluid-modelling-on-spherically-convergent-shear-waves-during-blunt-head-trauma
#2
Amit Madhukar, Ying Chen, Martin Ostoja-Starzewski
The MRI-based computational model, previously validated by tagged MRI and HARP imaging analysis technique on in vivo human brain deformation, is employed to study transient wave dynamics during blunt head trauma. Three different constitutive models are used for the cerebrospinal fluid (CSF): incompressible solid elastic, viscoelastic and fluid-like elastic using an equation of state model. Three impact cases are simulated which indicate that the blunt impacts give rise not only to a fast pressure wave but also to a slow, and potentially much more damaging, shear (distortional) wave that converges spherically towards the brain center...
March 14, 2017: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/28291491/an-augmented-reality-based-approach-for-surgical-telementoring-in-austere-environments
#3
Dan Andersen, Voicu Popescu, Maria Eugenia Cabrera, Aditya Shanghavi, Brian Mullis, Sherri Marley, Gerardo Gomez, Juan P Wachs
Telementoring can improve treatment of combat trauma injuries by connecting remote experienced surgeons with local less-experienced surgeons in an austere environment. Current surgical telementoring systems force the local surgeon to regularly shift focus away from the operating field to receive expert guidance, which can lead to surgery delays or even errors. The System for Telementoring with Augmented Reality (STAR) integrates expert-created annotations directly into the local surgeon's field of view. The local surgeon views the operating field by looking at a tablet display suspended between the patient and the surgeon that captures video of the surgical field...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28290929/advanced-trauma-life-support-time-standards
#4
Andrew B Hall, Felix S Boecker, Joseph M Shipp, Dennis Hanseman
INTRODUCTION: Trauma readiness is critical to military medicine. Without medical centers that include persistent volumes of trauma, simulation has become the means to maintain and practice those skills. To create those simulations, standards for both design and metrics to evaluate practitioners are required. MATERIALS AND METHODS: Forty-four traumas were monitored and times to completion of the various steps of Advanced Trauma Life Support were recorded and tabulated...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28289914/firecracker-eye-exposure-experimental-study-and-simulation
#5
Chiara Clemente, Luca Esposito, Domenico Speranza, Nicola Bonora
Understanding the mechanisms of traumatic ocular injury is helpful to make accurate diagnoses before the symptoms emerge and to develop specific eye protection. The comprehension of the dynamics of primary blast injury mechanisms is a challenging issue. The question is whether the pressure wave propagation and reflection alone could cause ocular damage. To date, there are dissenting opinions and no conclusive evidence thereupon. A previous numerical investigation of blast trauma highlighted the dynamic effect of pressure propagation and its amplification by the geometry of the bony orbit, inducing a resonance cavity effect and a standing wave hazardous for eye tissues...
March 13, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28286528/evaluation-of-a-pilot-project-to-introduce-simulation-based-team-training-to-pediatric-surgery-trauma-room-care
#6
Markus Lehner, Ellen Heimberg, Florian Hoffmann, Oliver Heinzel, Hans-Joachim Kirschner, Martina Heinrich
Introduction. Several studies in pediatric trauma care have demonstrated substantial deficits in both prehospital and emergency department management. Methods. In February 2015 the PAEDSIM collaborative conducted a one and a half day interdisciplinary, simulation based team-training course in a simulated pediatric emergency department. 14 physicians from the medical fields of pediatric surgery, pediatric intensive care and emergency medicine, and anesthesia participated, as well as four pediatric nurses. After a theoretical introduction and familiarization with the simulator, course attendees alternately participated in six simulation scenarios and debriefings...
2017: International Journal of Pediatrics
https://www.readbyqxmd.com/read/28279202/systemic-administration-of-mesenchymal-stem-cells-combined-with-parathyroid-hormone-therapy-synergistically-regenerates-multiple-rib-fractures
#7
Doron Cohn Yakubovich, Dmitriy Sheyn, Maxim Bez, Yeshai Schary, Eran Yalon, Afeef Sirhan, May Amira, Alin Yaya, Sandra De Mel, Xiaoyu Da, Shiran Ben-David, Wafa Tawackoli, Eric J Ley, Dan Gazit, Zulma Gazit, Gadi Pelled
BACKGROUND: A devastating condition that leads to trauma-related morbidity, multiple rib fractures, remain a serious unmet clinical need. Systemic administration of mesenchymal stem cells (MSCs) has been shown to regenerate various tissues. We hypothesized that parathyroid hormone (PTH) therapy would enhance MSC homing and differentiation, ultimately leading to bone formation that would bridge rib fractures. METHODS: The combination of human MSCs (hMSCs) and a clinically relevant PTH dose was studied using immunosuppressed rats...
March 9, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28262203/development-and-evaluation-of-a-trauma-decision-making-simulator-in-oculus-virtual-reality
#8
Cuan M Harrington, Dara O Kavanagh, John F Quinlan, Donncha Ryan, Patrick Dicker, Dara O'Keeffe, Oscar Traynor, Sean Tierney
BACKGROUND: Consumer-available virtual-reality technology was launched in 2016 with strong foundations in the entertainment-industry. We developed an innovative medical-training simulator on the Oculus™ Gear-VR platform. This novel application was developed utilising internationally recognised Advanced Trauma Life Support (ATLS) principles, requiring decision-making skills for critically-injured virtual-patients. METHODS: Participants were recruited in June, 2016 at a single-centre trauma-course (ATLS, Leinster, Ireland) and trialled the platform...
February 10, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28257393/potential-role-of-platelet-leukocyte-aggregation-in-trauma-induced-coagulopathy-ex-vivo-findings
#9
Johannes Zipperle, Katrin Altenburger, Martin Ponschab, Christoph J Schlimp, Andreas Spittler, Soheyl Bahrami, Heinz Redl, Herbert Schöchl
BACKGROUND: Platelet dysfunction has been identified as an important contributor of trauma-induced coagulopathy (TIC) but the underlying mechanism still remains to be elucidated. Trauma-associated pro-inflammatory stimuli strongly activate leukocytes, which in turn bind activated platelets. Therefore, we investigated the role of platelet-leukocyte aggregation (PLA) as a potential feature of trauma-induced platelet dysfunction. METHODS: Whole blood from 10 healthy donors was exposed to selective and collective platelet and leukocyte agonists in order to simulate differential states of activation...
March 2, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28247305/virtual-laparoscopic-training-system-based-on-vch-model
#10
Jiangzhou Tang, Lang Xu, Longjun He, Songluan Guan, Xing Ming, Qian Liu
Laparoscopy has been widely used to perform abdominal surgeries, as it is advantageous in that the patients experience lower post-surgical trauma, shorter convalescence, and less pain as compared to traditional surgery. Laparoscopic surgeries require precision; therefore, it is imperative to train surgeons to reduce the risk of operation. Laparoscopic simulators offer a highly realistic surgical environment by using virtual reality technology, and it can improve the training efficiency of laparoscopic surgery...
April 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28237081/incidence-of-posterior-interosseous-nerve-trauma-during-creation-of-the-3-4-wrist-arthroscopy-portal-in-cadavers
#11
Andre Eu-Jin Cheah, Wei Le, Jeffrey Yao
PURPOSE: To describe histologic evidence of nerve trauma during the creation and use of the 3-4 portal. METHODS: Fourteen fresh-frozen cadaveric wrists were mounted on a custom-built frame that simulated a wrist arthroscopy traction tower. After the 3-4 portal was created in the usual manner, the skin was dissected off to identify possible trauma to the posterior interosseous nerve (PIN). Specimens were categorized into those where there was clearly no trauma to the PIN and those where trauma was possible...
February 22, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28236302/pathogen-inactivation-treatment-of-plasma-and-platelet-concentrates-and-their-predicted-functionality-in-massive-transfusion-protocols
#12
Ahmad F Arbaeen, Peter Schubert, Katherine Serrano, Cedric J Carter, Brankica Culibrk, Dana V Devine
BACKGROUND: Trauma transfusion packages for hemorrhage control consist of red blood cells, plasma, and platelets at a set ratio. Although pathogen reduction improves the transfusion safety of platelet and plasma units, there is an associated reduction in quality. This study aimed to investigate the impact of riboflavin/ultraviolet light-treated plasma or platelets in transfusion trauma packages composed of red blood cell, plasma, and platelet units in a ratio of 1:1:1 in vitro by modeling transfusion scenarios for trauma patients and assessing function by rotational thromboelastometry...
February 24, 2017: Transfusion
https://www.readbyqxmd.com/read/28222391/a-clinically-applicable-non-invasive-method-to-quantitatively-assess-the-visco-hyperelastic-properties-of-human-heel-pad-implications-for-assessing-the-risk-of-mechanical-trauma
#13
Sara Behforootan, Panagiotis E Chatzistergos, Nachiappan Chockalingam, Roozbeh Naemi
INTRODUCTION: Pathological conditions such as diabetic foot and plantar heel pain are associated with changes in the mechanical properties of plantar soft tissue. However, the causes and implications of these changes are not yet fully understood. This is mainly because accurate assessment of the mechanical properties of plantar soft tissue in the clinic remains extremely challenging. PURPOSE: To develop a clinically viable non-invasive method of assessing the mechanical properties of the heel pad...
February 9, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28213166/influence-of-clamping-stress-and-duration-on-the-trauma-of-liver-tissue-during-surgery-operation
#14
Jin Wang, Qing-Yuan Yu, Wei Li, Bing-Rui Wang, Zhong-Rong Zhou
BACKGROUND: Tissue grasping damage often occurs in minimally invasive surgery, which would increase the postoperative recovery time and the risk of surgical complications. The purpose of this study was to evaluate the relationship between liver tissue trauma and compression stress magnitude and duration during tissue clamping operation. METHODS: The clamping experiments of liver tissues in vivo were conducted by using a universal soft tissue mechanical testing machine under different clamping stress magnitudes and durations...
February 10, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28198793/proximity-and-risks-of-the-anterior-neurovascular-and-tendinous-anatomy-of-the-distal-leg-relative-to-anteriorly-applied-distal-locking-screws-for-tibia-nailing-a-plea-for-open-insertion
#15
Phillip M Mitchell, Cory A Collinge, Eric Barcak, Edward Perez, Kostas Triantafillou
PURPOSE: To determine the proximity and potential risks to distal leg anatomy from anterior to posteriorly (A-P) applied distal tibia locking screws for tibial nailing. DESIGN: Retrospective. SETTING: ACS level I trauma center. PATIENTS/PARTICIPANTS: Twenty consecutive adult patients undergoing computed tomograms with intravenous contrast (CTAs) on uninjured legs. MAIN OUTCOME MEASUREMENTS: Simulated 5 mm distal interlocking screws placed in the A-P axis of an ideally placed tibial nail at 10 mm increments from the tibial plafond (10 to 40mm) were studied in relation to the distal leg's anterior anatomy...
February 14, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28192029/the-n-by-t-target-discharge-strategy-for-inpatient-units
#16
Pratik J Parikh, Nicholas Ballester, Kylie Ramsey, Nan Kong, Nancy Pook
BACKGROUND: Ineffective inpatient discharge planning often causes discharge delays and upstream boarding. While an optimal discharge strategy that works across all units at a hospital is likely difficult to identify and implement, a strategy that provides a reasonable target to the discharge team appears feasible. METHODS: We used observational and retrospective data from an inpatient trauma unit at a Level 2 trauma center in the Midwest US. Our proposed novel n-by-T strategy-discharge n patients by the Tth hour-was evaluated using a validated simulation model...
February 1, 2017: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/28188471/visualization-of-vascular-injuries-in-extremity-trauma
#17
Kwitae Chong, Chenfanfu Jiang, Daniel Ram, Anand Santhanam, Demetri Terzopoulos, Peyman Benharash, Erik Dutson, Joseph Teran, Jeff D Eldredge
A tandem of particle-based computational methods is adapted to simulate injury and hemorrhage in the human body. In order to ensure anatomical fidelity, a three-dimensional model of a targeted portion of the human body is reconstructed from a dense sequence of CT scans of an anonymized patient. Skin, bone and muscular tissue are distinguished in the imaging data and assigned with their respective material properties. An injury geometry is then generated by simulating the mechanics of a ballistic projectile passing through the anatomical model with the material point method...
February 11, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/28167239/6-gingerol-protects-intestinal-barrier-from-ischemia-reperfusion-induced-damage-via-inhibition-of-p38-mapk-to-nf-%C3%AE%C2%BAb-signalling
#18
Yanli Li, Bin Xu, Ming Xu, Dapeng Chen, Yongjian Xiong, Mengqiao Lian, Yuchao Sun, Zeyao Tang, Li Wang, Chunling Jiang, Yuan Lin
Intestinal ischemia reperfusion (I/R) injury caused by severe trauma, intestinal obstruction, and operation is one of the tough challenges in clinic. 6-Gingerol (6G), a main active ingredient of ginger, is found to have anti-microbial, anti-inflammatory, anti-oxidative, and anti-cancer activities. The present study was designed to characterize the potential protective effects of 6G on rat intestinal I/R injury and reveal the correlated mechanisms. Rat intestinal I/R model was established with clamping the superior mesenteric artery (SMA) and 6G was intragastrically administered for three consecutive days before I/R injury...
February 4, 2017: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/28153385/video-review-as-a-tool-to-improve-orthopedic-residents-performance-of-closed-manipulative-reductions
#19
Nickul S Jain, Ran Schwarzkopf, John A Scolaro
OBJECTIVE: Orthopedic residents commonly perform closed manipulative reductions as a part of their training. Traditionally, this skill is taught early in training but difficult to simulate. Proficiency is achieved through repetition and experience; faculty observation and instruction is unfortunately often limited. Direct resident teaching has been shown to increase competency, comfort, and long-term skill retention. We hypothesize that video review of closed fracture reductions will provide an inexpensive and valuable tool for resident education and improve skill performance...
January 30, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28146451/training-effectiveness-of-a-wide-area-virtual-environment-in-medical-simulation
#20
Grady S Wier, Rebekah Tree, Rasha Nusr
INTRODUCTION: The success of war fighters and medical personnel handling traumatic injuries largely depends on the quality of training they receive before deployment. The purpose of this study was to gauge the utility of a Wide Area Virtual Environment (WAVE) as a training adjunct by comparing and evaluating student performance, measuring sense of realism, and assessing the impact on student satisfaction with their training exposure in an immersive versus a field environment. METHODS: This comparative prospective cohort study examined the utility of a three-screen WAVE where subjects were immersed in the training environment with medical simulators...
February 2017: Simulation in Healthcare: Journal of the Society for Simulation in Healthcare
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