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https://www.readbyqxmd.com/read/28550763/mechanical-properties-of-a-nanoporous-membrane-used-in-implantable-medical-devices-correlation-between-experimental-characterization-and-2d-numerical-simulation
#1
F Cristofari, B Piotrowski, R Pesci
Nanoporous membranes are used for the elaboration of implantable medical devices. In order to guaranty their integrity after implantation in a patient body, it is necessary to characterize the microstructure and the mechanical behavior of such membranes. They present randomly distributed pores around 1µm in diameter at the surface. X-ray nanotomography permits to get the geometry of the pores through the thickness with a reduction of the diameter in the core. A multiscale study is done to characterize the membranes: macroscopic tensile tests permit to get the behavior law of the non porous material and in situ tensile tests are carried on in a Scanning Electron Microscope in order to observe the evolution of pores and cracks during loading...
May 18, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28550762/forensic-age-estimation-by-morphometric-analysis-of-the-manubrium-from-3d-mr-images
#2
Naira P Martínez Vera, Johannes Höller, Thomas Widek, Bernhard Neumayer, Thomas Ehammer, Martin Urschler
Forensic age estimation research based on skeletal structures focuses on patterns of growth and development using different bones. In this work, our aim was to study growth-related evolution of the manubrium in living adolescents and young adults using magnetic resonance imaging (MRI), which is an image acquisition modality that does not involve ionizing radiation. In a first step, individual manubrium and subject features were correlated with age, which confirmed a statistically significant change of manubrium volume (Mvol:p<0...
May 12, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28550724/soil-erosion-predictions-from-a-landscape-evolution-model-an-assessment-of-a-post-mining-landform-using-spatial-climate-change-analogues
#3
G R Hancock, D Verdon-Kidd, J B C Lowry
Landscape Evolution Modelling (LEM) technologies provide a means by which it is possible to simulate the long-term geomorphic stability of a conceptual rehabilitated landform. However, simulations rarely consider the potential effects of anthropogenic climate change and consequently risk not accounting for the range of rainfall variability that might be expected in both the near and far future. One issue is that high resolution (both spatial and temporal) rainfall projections incorporating the potential effects of greenhouse forcing are required as input...
May 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28549363/-thoracic-inestability-fixed-with-bioabsorbable-screws-and-plates
#4
A L Nolasco-de la Rosa, R Mosiñoz-Montes, J Matehuala-García, A A Cuautle-Ramírez, E Román-Guzmán, A L Reyes-Miranda, F Quero-Sandoval
BACKGROUND: Flail chest is managed with mechanical ventilation or inhaloteraphy and analgesia. Little has been published on the use of bioabsorbable material and its evolution in flail chest fixation. METHODS: This is a descriptive study of patients with unstable chest undergoing fixation with bioabsorbable plates and screws in a period from February 2009 to December 2011. RESULTS: We report 18 cases, aged 33-74 years (mean 53), three with bilateral involvement; rib fixation was performed between 1-21 days of the accident (mean 1...
November 2016: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/28549238/risk-factors-and-mechanisms-contributing-to-tki-induced-vascular-events-in-patients-with-cml
#5
REVIEW
Peter Valent, Emir Hadzijusufovic, Gregor Hoermann, Wolfgang Füreder, Gerit-Holger Schernthaner, Wolfgang R Sperr, Rudolf Kirchmair, Dominik Wolf
Vascular adverse events (VAE) are an emerging problem in patients with chronic myeloid leukemia (CML) receiving second-generation BCR-ABL1 tyrosine kinase inhibitors (TKI). Relevant VAE comprise peripheral, cerebral, and coronary artery changes in patients receiving nilotinib, venous and arterial occlusive events during ponatinib therapy, and pulmonary hypertension in patients receiving dasatinib. Although each TKI binds to a unique profile of molecular targets in leukemic cells and vascular cells, the exact etiology of drug-induced vasculopathies remains uncertain...
May 12, 2017: Leukemia Research
https://www.readbyqxmd.com/read/28549050/use-of-noncontact-low-frequency-ultrasound-in-deep-tissue-pressure-injury-a-retrospective-analysis
#6
Pamela Wagner-Cox, Heather M Duhame, Christina R Jamison, Robin R Jackson, Suzy T Fehr
PURPOSE: The purpose of this study was to examine the effect of noncontact low-frequency ultrasound (NLFU) on deep tissue pressure injury (DTPI), both hospital-acquired and those present on admission (POA). DESIGN: Retrospective, descriptive study. SAMPLE AND SETTING: Medical records from 44 adult patients with a DTPI treated with NLFU were reviewed; 22 had a hospital-acquired DTPI (HADTPI) and 22 had DTPI POA. Their mean age was 71.3 ± 16...
May 25, 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28548975/factor-vii-activating-protease-sex-related-association-with-coronary-artery-calcification
#7
Ramshanker Ramanathan, Jørgen B Gram, Niels Peter R Sand, Bjarne L Nørgaard, Axel C P Diederichsen, Frank Vitzthum, Herbert Schwarz, Johannes J Sidelmann
: Factor VII-activating protease (FSAP) may regulate development of cardiovascular disease (CVD). We evaluated sex differences in FSAP measures and examined the association between FSAP and coronary artery calcification (CAC) in a middle-aged population. Participants were randomly selected citizens aged 50 or 60 without CVD, diabetes mellitus, Marburg I polymorphism, or hormone replacement therapy (HRT). FSAP protein concentration (total FSAP), FSAP urokinase-activating capacity (FSAP GP), and FSAP GP/total FSAP (specific FSAP activity) were measured...
May 25, 2017: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/28548523/strength-and-viscosity-effects-on-perturbed-shock-front-stability-in-metals
#8
S Opie, E Loomis, P Peralta, T Shimada, R P Johnson
Computational modeling and experimental measurements on metal samples subject to a laser-driven, ablative Richtmyer-Meshkov instability showed differences between viscosity and strength effects. In particular, numerical and analytical solutions, coupled with measurements of fed-through perturbations, generated by perturbed shock fronts onto initially flat surfaces, show promise as a validation method for models of deviatoric response in the postshocked material. Analysis shows that measurements of shock perturbation amplitudes at low sample thickness-to-wavelength ratios are not enough to differentiate between strength and viscosity effects, but that surface displacement data of the fed-through perturbations appears to resolve the ambiguity...
May 12, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28548291/practitioner-review-empirical-evolution-of-youth-psychotherapy-toward-transdiagnostic-approaches
#9
REVIEW
Lauren Krumholz Marchette, John R Weisz
BACKGROUND: Psychotherapy for children and adolescents (herein, 'youths') has grown more precise and focused over the decades, shifting toward empirically supported treatments standardized via therapist manuals. The manuals have increasingly emphasized precise targeting of single disorders or problems, or homogenous clusters. These focal treatments represent a valuable advance, with intervention benefit documented in hundreds of studies. However, relatively few of these treatments are widely used in everyday clinical practice, and their level of benefit may not be ideal, particularly in practice contexts and when compared to usual clinical care...
May 26, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28548083/atomic-scale-age-resolution-of-planetary-events
#10
L F White, J R Darling, D E Moser, D A Reinhard, T J Prosa, D Bullen, D Olson, D J Larson, D Lawrence, I Martin
Resolving the timing of crustal processes and meteorite impact events is central to understanding the formation, evolution and habitability of planetary bodies. However, identifying multi-stage events from complex planetary materials is highly challenging at the length scales of current isotopic techniques. Here we show that accurate U-Pb isotopic analysis of nanoscale domains of baddeleyite can be achieved by atom probe tomography. Within individual crystals of highly shocked baddeleyite from the Sudbury impact structure, three discrete nanostructural domains have been isolated yielding average (206)Pb/(238)U ages of 2,436±94 Ma (protolith crystallization) from homogenous-Fe domains, 1,852±45 Ma (impact) from clustered-Fe domains and 1,412±56 Ma (tectonic metamorphism) from planar and subgrain boundary structures...
May 26, 2017: Nature Communications
https://www.readbyqxmd.com/read/28546568/textured-nise2-film-bifunctional-electrocatalyst-for-full-water-splitting-at-remarkably-low-overpotential-with-high-energy-efficiency
#11
Abdurazag T Swesi, Jahangir Masud, Wipula P R Liyanage, Siddesh Umapathi, Eric Bohannan, Julia Medvedeva, Manashi Nath
Herein we have shown that electrodeposited NiSe2 can be used as a bifunctional electrocatalyst under alkaline conditions to split water at very low potential by catalyzing both oxygen evolution and hydrogen evolution reactions at anode and cathode, respectively, achieving a very high electrolysis energy efficiency exceeding 80% at considerably high current densities (100 mA cm(-2)). The OER catalytic activity as well as electrolysis energy efficiency surpasses any previously reported OER electrocatalyst in alkaline medium and energy efficiency of an electrolyzer using state-of-the-art Pt and RuO2 as the HER and OER catalyst, respectively...
May 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28546383/drosophila-simulans-a-species-with-improved-resolution-in-evolve-and-resequence-studies
#12
Neda Barghi, Raymond Tobler, Viola Nolte, Christian Schlötterer
The combination of experimental evolution with high-throughput sequencing of pooled individuals - i.e. Evolve and Resequence; E&R - is a powerful approach to study adaptation from standing genetic variation under controlled, replicated conditions. Nevertheless, E&R studies in Drosophila melanogaster have frequently resulted in inordinate numbers of candidate SNPs, particularly for complex traits. Here, we contrast the genomic signature of adaptation following ~60 generations in a novel hot environment for D...
May 25, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28545932/the-association-between-tau-pet-and-retrospective-cortical-thinning-in-clinically-normal-elderly
#13
Molly R LaPoint, Jasmeer P Chhatwal, Jorge Sepulcre, Keith A Johnson, Reisa A Sperling, Aaron P Schultz
Tau pathology has been associated with neuronal loss at autopsy, but the temporal evolution of tau pathology and atrophy remains unclear. Here, we investigate the association between cross-sectional AV-1451-PET as a marker of tau pathology and cortical thickness cross-sectionally. We also investigated retrospective rates of cortical thinning over the three years preceding the AV-1451 scan in a clinically normal cohort of 103 older adults from the Harvard Aging Brain Study. Tau measurements were Geometric Transfer Matrix partial volume corrected standardized uptake value ratios (SUVRs) with a cerebellar grey reference region...
May 22, 2017: NeuroImage
https://www.readbyqxmd.com/read/28544153/simulated-climate-change-epidemic-size-and-host-evolution-across-host-parasite-populations
#14
Stuart K J R Auld, June Brand
Climate change is causing warmer and more variable temperatures as well as physical flux in natural populations, which will affect the ecology and evolution of infectious disease epidemics. Using replicate semi-natural populations of a coevolving freshwater invertebrate-parasite system (host: Daphnia magna, parasite: Pasteuria ramosa), we quantified the effects of ambient temperature and population mixing (physical flux within populations) on epidemic size and population health. Each population was seeded with an identical suite of host genotypes and dose of parasite transmission spores...
May 22, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28543028/correlated-evolution-between-colouration-and-ambush-site-in-predators-with-visual-prey-lures
#15
F M Gawryszewski, M A Calero-Torralbo, R G Gillespie, M A Rodríguez-Gironés, M E Herberstein
The evolution of a visual signal will be affected by signaller and receiver behaviour, and by the physical properties of the environment where the signal is displayed. Crab spiders are typical sit-and-wait predators found in diverse ambush sites, such as tree bark, foliage and flowers. Some of the flower-dweller species present a UV(+) -white visual lure that makes them conspicuous and attractive to their prey. We hypothesised that UV(+) -white colouration was associated with the evolution of a flower-dwelling habit...
May 23, 2017: Evolution; International Journal of Organic Evolution
https://www.readbyqxmd.com/read/28542908/an-appraisal-of-the-enzyme-stability-activity-trade-off
#16
Scott R Miller
A longstanding idea in evolutionary physiology is that an enzyme cannot jointly optimize performance at both high and low temperatures due to a trade-off between stability and activity. Although a stability-activity trade-off has been observed for well-characterized examples, such a trade-off is not imposed by any physical chemical constraint. To better understand the pervasiveness of this trade-off, I investigated the stability-activity relationship for comparative biochemical studies of purified orthologous enzymes identified by a literature search...
May 24, 2017: Evolution; International Journal of Organic Evolution
https://www.readbyqxmd.com/read/28542596/progressive-mitochondrial-protein-lysine-acetylation-and-heart-failure-in-a-model-of-friedreich-s-ataxia-cardiomyopathy
#17
Amanda R Stram, Gregory R Wagner, Brian D Fogler, P Melanie Pride, Matthew D Hirschey, R Mark Payne
INTRODUCTION: The childhood heart disease of Friedreich's Ataxia (FRDA) is characterized by hypertrophy and failure. It is caused by loss of frataxin (FXN), a mitochondrial protein involved in energy homeostasis. FRDA model hearts have increased mitochondrial protein acetylation and impaired sirtuin 3 (SIRT3) deacetylase activity. Protein acetylation is an important regulator of cardiac metabolism and loss of SIRT3 increases susceptibility of the heart to stress-induced cardiac hypertrophy and ischemic injury...
2017: PloS One
https://www.readbyqxmd.com/read/28542519/characterization-of-the-whole-chloroplast-genome-of-chikusichloa-mutica-and-its-comparison-with-other-rice-tribe-oryzeae-species
#18
Zhiqiang Wu, Cuihua Gu, Luke R Tembrock, Dong Zhang, Song Ge
Chloroplast genomes are a significant genomic resource in plant species and have been used in many research areas. The complete genomic information from wild crop species could supply a valuable genetic reservoir for breeding. Chikusichloa mutica is one of the most important wild distant relatives of cultivated rice. In this study, we sequenced and characterized its complete chloroplast (cp) genome and compared it with other species in the same tribe. The whole cp genome sequence is 136,603 bp in size and exhibits a typical quadripartite structure with large and small single-copy regions (LSC, 82,327 bp; SSC, 12,598 bp) separated by a pair of 20,839-bp inverted repeats (IRA, B)...
2017: PloS One
https://www.readbyqxmd.com/read/28542058/a-personal-history-of-the-evolution-of-health-status-assessment
#19
James N Burdine, Michael R J Felix
No abstract text is available yet for this article.
July 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28539904/the-neural-systems-of-forgiveness-an-evolutionary-psychological-perspective
#20
REVIEW
Joseph Billingsley, Elizabeth A R Losin
Evolution-minded researchers posit that the suite of human cognitive adaptations may include forgiveness systems. According to these researchers, forgiveness systems regulate interpersonal motivation toward a transgressor in the wake of harm by weighing multiple factors that influence both the potential gains of future interaction with the transgressor and the likelihood of future harm. Although behavioral research generally supports this evolutionary model of forgiveness, the model's claims have not been examined with available neuroscience specifically in mind, nor has recent neuroscientific research on forgiveness generally considered the evolutionary literature...
2017: Frontiers in Psychology
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