keyword
MENU ▼
Read by QxMD icon Read
search

Sapiens 3

keyword
https://www.readbyqxmd.com/read/29909110/comprehensive-echocardiographic-assessment-of-normal-transcatheter-valve-function
#1
Rebecca T Hahn, Jonathon Leipsic, Pamela S Douglas, Wael A Jaber, Neil J Weissman, Philippe Pibarot, Philipp Blanke, Jae K Oh
OBJECTIVES: This study aims to establish parameters for identifying normal function for each of the 3 iterations of balloon-expandable valves and 2 iterations of self-expanding valves. BACKGROUND: Expected transthoracic echocardiographic Doppler-derived hemodynamic data for transcatheter aortic valves inform pre-implant decision-making and post-implanted monitoring of longitudinal valve function. METHODS: We collected the Echocardiography Core Lab measured mean gradients and effective orifice area (EOA) from discharge or 30-day echocardiograms from randomized trials; the PARTNER (Placement of Aortic Transcatheter Valves) trials for the balloon-expandable valves and the Medtronic CoreValve US Pivotal trial and Medtronic CoreValve Evolut R United States IDE Clinical Study for the self-expanding valves...
June 8, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29899442/author-correction-new-fossils-from-jebel-irhoud-morocco-and-the-pan-african-origin-of-homo-sapiens
#2
Jean-Jacques Hublin, Abdelouahed Ben-Ncer, Shara E Bailey, Sarah E Freidline, Simon Neubauer, Matthew M Skinner, Inga Bergmann, Adeline Le Cabec, Stefano Benazzi, Katerina Harvati, Philipp Gunz
In the originally published version of this Letter, the x axis in Fig. 3a should have been: 'PC1: 26%' rather than 'PC1: 46%', and the y axis should have been: 'PC2: 16%' rather than 'PC2: 29%'. We also noticed an error in the numbering of the fossils from Qafzeh: Qafzeh 27 should be removed, and Qafzeh 26 is actually Qafzeh 25, following Tillier (2014)1 and Schuh et al. (2017)2 and personal communication with B. Vandermeersch and M. D. Garralda. The correct enumeration of Qafzeh samples in the 'Mandibular metric data' section of the Methods is therefore: 'Qafzeh (9, 25)' rather than 'Qafzeh (9, 26, 27)'...
June 13, 2018: Nature
https://www.readbyqxmd.com/read/29891375/silence-of-ryanodine-receptor-gene-decreases-susceptibility-to-chlorantraniliprole-in-the-oriental-armyworm-mythimna-separata-walker
#3
Jin-Da Wang, Li-Fei Chen, Ya-Ru Wang, Hua-Ying Fu, Ahmad Ali, Da Xiao, Ran Wang, San-Ji Gao
The ryanodine receptors of insects are the main target sites of diamide insecticides, which show highly selective insecticidal activity relative to toxicity in mammals and provide a novel option for managing lepidopteran pests. The oriental armyworm, Mythimna separata (Walker), is a destructive pest of agricultural crops, and great efforts have been undertaken to control this pest including repeated insecticide applications. In this study, full-length cDNA of a ryanodine receptor gene from M. separata (MsRyR) was cloned and characterized...
June 2018: Pesticide Biochemistry and Physiology
https://www.readbyqxmd.com/read/29877717/surgical-antegrade-transcatheter-valve-implantation-and-heavily-calcified-heart
#4
Elise Lupon, Anais Lemaire, Christophe Cron, Bertrand Marcheix
It is well known that a heavily calcified mitral valve significantly increases the perioperative and postoperative risks of mitral valve surgery. A 71-year-old woman was referred to our department with severe mitral valve disease. Cardiac imaging revealed extremely severe calcification of the entire left heart. Surgery was performed through a median sternotomy with standard cardiopulmonary bypass. After dilating the mitral orifice with a balloon, we replaced the valve with a transcatheter Edwards Sapiens 3 aortic valve under direct vision...
January 1, 2018: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/29860075/effect-of-sapien-3-transcatheter-valve-implantation-on-health-status-in-patients-with-severe-aortic-stenosis-at-intermediate-surgical-risk-results-from-the-partner-s3i-trial
#5
Suzanne J Baron, Vinod H Thourani, Susheel Kodali, Suzanne V Arnold, Kaijun Wang, Elizabeth A Magnuson, Augusto D Pichard, Vasilis Babaliaros, Isaac George, D Craig Miller, Murat Tuzcu, Kevin Greason, Howard C Herrmann, Craig R Smith, Martin B Leon, David J Cohen
OBJECTIVES: The aim of this study was to evaluate whether transcatheter aortic valve replacement (TAVR) with the SAPIEN 3 valve (S3-TAVR) results in improved quality of life (QoL) compared with previous-generation TAVR devices or surgical aortic valve replacement (SAVR). BACKGROUND: In patients with severe aortic stenosis at intermediate surgical risk, TAVR using the SAPIEN XT valve (XT-TAVR) results in similar QoL compared with SAVR. Compared with SAPIEN XT, the SAPIEN 3 valve offers a lower delivery profile and modifications to reduce paravalvular regurgitation...
May 25, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29858081/irna-3typea-identifying-three-types-of-modification-at-rna-s-adenosine-sites
#6
Wei Chen, Pengmian Feng, Hui Yang, Hui Ding, Hao Lin, Kuo-Chen Chou
RNA modifications are additions of chemical groups to nucleotides or their local structural changes. Knowledge about the occurrence sites of these modifications is essential for in-depth understanding of the biological functions and mechanisms and for treating some genomic diseases as well. With the avalanche of RNA sequences generated in the post-genomic age, many computational methods have been proposed for identifying various types of RNA modifications one by one. However, so far no method whatsoever has been developed for simultaneously identifying several different types of RNA modifications...
June 1, 2018: Molecular Therapy. Nucleic Acids
https://www.readbyqxmd.com/read/29807762/high-resolution-three-dimensional-strain-mapping-of-bioprosthetic-heart-valves-using-digital-image-correlation
#7
Mostafa Abbasi, Dong Qiu, Yashar Behnam, Danny Dvir, Chadd Clary, Ali N Azadani
Transcatheter aortic valve replacement (TAVR) is a safe and effective treatment option for patients deemed at high and intermediate risk for surgical aortic valve replacement. Similar to surgical aortic valves (SAVs), transcatheter aortic valves (TAVs) undergo calcification and mechanical wear over time. However, to date, there have been limited publications on the long-term durability of TAV devices. To assess longevity and mechanical strength of TAVs in comparison to surgical bioprosthetic valves, three-dimensional deformation analysis and strain measurement of the leaflets become an inevitable part of the evaluation...
May 22, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29795254/inference-of-ecological-and-social-drivers-of-human-brain-size-evolution
#8
Mauricio González-Forero, Andy Gardner
The human brain is unusually large. It has tripled in size from Australopithecines to modern humans 1 and has become almost six times larger than expected for a placental mammal of human size 2 . Brains incur high metabolic costs 3 and accordingly a long-standing question is why the large human brain has evolved 4 . The leading hypotheses propose benefits of improved cognition for overcoming ecological5-7 , social8-10 or cultural11-14 challenges. However, these hypotheses are typically assessed using correlative analyses, and establishing causes for brain-size evolution remains difficult15,16 ...
May 2018: Nature
https://www.readbyqxmd.com/read/29765111/new-insights-into-apoptosome-structure-and-function
#9
REVIEW
Loretta Dorstyn, Christopher W Akey, Sharad Kumar
The apoptosome is a platform that activates apical procaspases in response to intrinsic cell death signals. Biochemical and structural studies in the past two decades have extended our understanding of apoptosome composition and structure, while illuminating the requirements for initiator procaspase activation. A number of studies have now provided high-resolution structures for apoptosomes from C. elegans (CED-4), D. melanogaster (Dark), and H. sapiens (Apaf-1), which define critical protein interfaces, including intra and interdomain interactions...
May 15, 2018: Cell Death and Differentiation
https://www.readbyqxmd.com/read/29762934/rescue-tavi-for-aortic-regurgitation-after-left-ventricular-assist-device-implantation-following-preoperative-impella%C3%A2-support
#10
Florian E M Herrmann, Petra Wellmann, Vera von Dossow, Steffen Massberg, Christian Hagl, René Schramm, Maximilian Pichlmaier
A patient presented with a decompensated cardiomyopathy requiring invasive hemodynamic support with an Impella® heart pump. Extracorporeal life support (ECLS) became necessary during the further course and the patient was bridged to left ventricular assist device (LVAD) implantation. Postoperatively, the patient did not improve as expected due to new aortic regurgitation (AR) that was most likely caused by the previously placed Impella. A SAPIEN 3 transcatheter aortic valve was implanted as a bail-out strategy; an additional valve-in-valve rescue was required due to paravalvular regurgitation...
September 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29753441/a-new-tephrochronology-for-early-diverse-stone-tool-technologies-and-long-distance-raw-material-transport-in-the-middle-to-late-pleistocene-kapthurin-formation-east-africa
#11
Nick Blegen, Brian R Jicha, Sally McBrearty
The Middle to Late Pleistocene (780-10 ka) of East Africa records evidence of significant behavioral change, early fossils of Homo sapiens, and the dispersals of our species across and out of Africa. Studying human evolution in this time period thus requires an extensive and precise chronology relating behavioral evidence from archaeological sequences to aspects of hominin biology and evidence of past environments from fossils and geological sequences. Tephrochronology provides the chronostratigraphic resolution to achieve this through correlation and dating of volcanic ashes...
May 9, 2018: Journal of Human Evolution
https://www.readbyqxmd.com/read/29735900/synthesis-biological-evaluation-and-docking-studies-of-novel-bisquaternary-aldoxime-reactivators-on-acetylcholinesterase-and-butyrylcholinesterase-inhibited-by-paraoxon
#12
Kamil Kuca, Daniel Jun, Lucie Junova, Kamil Musilek, Martina Hrabinova, Jorge Alberto Valle da Silva, Teodorico Castro Ramalho, Marian Valko, Qinghua Wu, Eugenie Nepovimova, Tanos Celmar Costa França
Nerve agents and oxon forms of organophosphorus pesticides act as strong irreversible inhibitors of two cholinesterases in the human body: acetylcholinesterase (AChE; EC 3.1.1.7) and butyrylcholinesterase (BChE; EC 3.1.1.8), and are therefore highly toxic compounds. For the recovery of inhibited AChE, antidotes from the group of pyridinium or bispyridinium aldoxime reactivators (pralidoxime, obidoxime, HI-6) are used in combination with anticholinergics and anticonvulsives. Therapeutic efficacy of reactivators (called “oximes”) depends on their chemical structure and also the type of organophosphorus inhibitor...
May 7, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29726601/comparison-of-paravalvular-aortic-leak-characteristics-in-the-medtronic-corevalve-versus-edwards-sapien-valve-paravalvular-aortic-leak-characteristics
#13
Olivia N Gilbert, Charles H Choi, Jodie L Franzil, Melissa Caughey, Waqas Qureshi, R Brandon Stacey, Min Pu, Robert J Applegate, Sanjay K Gandhi, David X M Zhao
OBJECTIVES: Temporally quantify and localize paravalvular aortic leak (PVL) after transcatheter aortic valve replacement (TAVR) in the Medtronic CoreValve (MCV) versus the Edwards Sapien Valve (ESV). BACKGROUND: In order to increase the precision of THV selection and PVL intervention, an understanding of PVL characteristics is essential. METHODS: The frequency, severity, and location of post-TAVR PVL were evaluated with transthoracic echocardiography pre-discharge, one month, and one-year post-procedure in 202 patients receiving a MCV (N = 120) or ESV (N = 81)...
May 4, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29706182/prognostic-impact-of-calcium-score-after-transcatheter-aortic-valve-implantation-performed-with-new-generation-prosthesis
#14
Mariama Akodad, Benoit Lattuca, Audrey Agullo, Jean-Christophe Macia, Thomas Gandet, Grégory Marin, Anaïs Iemmi, Hélène Vernhet, Laurent Schmutz, Nicolas Nagot, Bernard Albat, Guillaume Cayla, Florence Leclercq
Calcium score (CS) is a well-known prognostic factor after transcatheter aortic valve implantation (TAVI) performed with first generation prosthesis but few data are available concerning new generation valves. The aim of this study was to evaluate if CS remains a prognostic factor after Sapien 3 and Evolut R valves implantation. Agatston CS was evaluated on multislice computed tomography before TAVI in 346 patients implanted with Sapien XT (n = 61), CoreValve (n = 57) devices, (group 1, n = 118), and with new generation Sapien 3 (n = 147), Evolut R (n = 81) prosthesis, (group 2, n = 228)...
May 15, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29703437/incidence-predictors-and-impact-of-vascular-complications-after-transfemoral-transcatheter-aortic-valve-implantation-with-the-sapien-3-prosthesis
#15
Floortje van Kesteren, Martijn S van Mourik, Jeroen Vendrik, Esther M A Wiegerinck, José P S Henriques, Karel T Koch, Joanna J Wykrzykowska, Rob J de Winter, Jan J Piek, Krijn P van Lienden, Jim A Reekers, M Marije Vis, R Nils Planken, Jan Baan
Vascular complications (VCs) after transfemoral transcatheter aortic valve implantation (TAVI) have always been reported to occur frequently. Studies addressing VCs have been conducted with older-generation prostheses. We aimed to evaluate the incidence, predictors, and impact of VCs after transfemoral TAVI with the balloon-expandable SAPIEN 3. We report a single-center retrospective analysis of 400 consecutive patients of a prospectively acquired cohort. All patients underwent transfemoral TAVI with SAPIEN 3 between January 2014 and December 2016...
May 15, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29688322/conduction-dynamics-after-transcatheter-aortic-valve-implantation-and-implications-for-permanent-pacemaker-implantation-and-early-discharge-the-conduct-study
#16
Lennart van Gils, Sara Baart, Herbert Kroon, Zouhair Rahhab, Nahid El Faquir, Ramón Rodriguez Olivares, Yaar Aga, Anne-Marie Maugenest, Dominic A Theuns, Eric Boersma, Tamas Szili Torok, Peter P De Jaegere, Nicolas M Van Mieghem
Aims: To correlate dynamics in electrical conduction after transcatheter aortic valve implantation (TAVI) with need for permanent pacemaker implantation (PPM) and assess implications for early discharge. Methods and results: Daily electrocardiograms after TAVI were analysed for rhythm and conduction times and were correlated with PPM. Transcatheter aortic valve implantation was performed in 291 consecutive patients with three contemporary transcatheter heart valve designs: Medtronic CoreValve (n = 111), Edwards Sapien XT (n = 29) and Sapien 3 (n = 72), and Boston Lotus (n = 79)...
April 20, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29688174/matched-comparison-of-next-and-early-generation-balloon-expandable-transcatheter-heart-valve-implantations-in-failed-surgical-aortic-bioprostheses
#17
Moritz Seiffert, Hendrik Treede, Joachim Schofer, Axel Linke, Jochen Woehrle, Hardy Baumbach, Julinda Mehilli, Vinayak Bapat, Matheus Simonato, Thomas Walther, Mathias Kullmer, Peter Boekstegers, Stephan Ensminger, Thomas Kurz, Hélène Eltchaninoff, Ardawan Rastan, Nicolas Werner, Arend de Weger, Christian Frerker, Bernward Lauer, Olivier Muller, Brian Whisenant, Arun Thukkani, Giora Weisz, Danny Dvir
AIMS: Transcatheter valve-in-valve implantation (VinV) is established for the treatment of degenerated surgical bioprostheses in patients at high operative risk. Our aim was to report on the first large assessment of VinV with next generation balloon-expandable transcatheter heart valves. METHODS AND RESULTS: 514 patients after SAPIEN XT or SAPIEN 3 VinV were analyzed using an inverse probability of treatment weighting. Standardized clinical and hemodynamic outcomes were compared and core laboratory evaluation of implantation depth was performed...
April 24, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29673509/incidence-predictors-and-clinical-impact-of-prosthesis-patient-mismatch-following-transcatheter-aortic-valve-replacement-in-asian-patients-the-ocean-tavi-registry
#18
Masaki Miyasaka, Norio Tada, Masataka Taguri, Shigeaki Kato, Yusuke Enta, Tatsushi Otomo, Masaki Hata, Yusuke Watanabe, Toru Naganuma, Motoharu Araki, Futoshi Yamanaka, Shinichi Shirai, Hiroshi Ueno, Kazuki Mizutani, Minoru Tabata, Akihiro Higashimori, Kensuke Takagi, Masanori Yamamoto, Kentaro Hayashida
OBJECTIVES: The authors sought to investigate the prevalence, risk factors, and mid-term mortality in Asian patients with prosthesis-patient mismatch (PPM) after transcatheter aortic valve replacement (TAVR). BACKGROUND: Little information is available on PPM after TAVR in Asian patients. METHODS: The authors included 1,558 patients enrolled in the OCEAN-TAVI (Optimized transCathEter vAlvular iNtervention) Japanese multicenter registry from October 2013 to July 2016 after excluding patients who died following TAVR before discharge...
April 23, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29627180/transatrial-implantation-of-a-transcatheter-heart-valve-for-severe-mitral-annular-calcification
#19
Fabien Praz, Omar K Khalique, Raymond Lee, Ramesh Veeragandham, Hyde Russell, Mayra Guerrero, Ashequl M Islam, David W Deaton, Tsuyoshi Kaneko, Susheel K Kodali, Martin B Leon, Vinayak Bapat, Hiroo Takayama, Michael A Borger, Isaac George
OBJECTIVE: To assess the outcomes of transatrial implantation of a transcatheter heart valve (THV) for the treatment of mitral valve disease with severe mitral annular calcification (MAC). METHODS: Implantation of a balloon-expandable THV was performed on cardiopulmonary bypass via left atrial exposure in patients considered at risk for left ventricular outflow tract obstruction. The anterior mitral valve leaflet was systematically resected and pledgeted sutures were placed to enhance stability and reduce paravalvular leak...
March 12, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29623280/neo-left-main-channel-creation-using-double-stenting-alongside-a-sapien-3-aortic-valve-bioprosthesis-for-left-main-coronary-obstruction-following-valve-in-valve-transcatheter-aortic-valve-replacement-a-case-report-with-review-of-literature
#20
Apurva D Patel, Thomas Haldis, Kais Al Balbissi, Timir Paul
Transcatheter aortic valve replacement in the setting of failed surgical bioprosthesis (valve-in-valve) is a valuable option for patients with bioprosthetic aortic stenosis or regurgitation who are deemed high risk for repeat open heart surgery. Although the procedure is successful with proper preprocedural assessment, instances of left main (LM) coronary artery ostium obstruction have been documented. We present a case of LM coronary obstruction in the immediate postoperative period following implantation of a 20-mm Edwards Sapien 3 valve inside the degenerated 21-mm Mitroflow bioprosthesis stenosis, which was treated with double stenting alongside the Edwards Sapien 3 valve creating a channel ("neo left main") that extended from mid-LM to the upper margin of the Edwards Sapien 3 valve...
January 2018: Journal of Investigative Medicine High Impact Case Reports
keyword
keyword
116416
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"