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https://www.readbyqxmd.com/read/29053048/neurofibromatosis-type-1-a-neuro-psycho-cutaneous-syndrome
#1
Christopher K H Burris, Michael A Stier, Shahriar Salamat, Shari Thomas, Simone Lauderdale, Meisha L Raven, Maria E Rodriguez, Devasis N Reddy, Heather D Potter, Daniel M Albert
Neurofibromatosis type 1 (NF1) is an inherited disorder often associated with optic nerve gliomas, low-grade brain tumors, and readily visible signs. Though these features are frequently emphasized, the psychosocial and emotional morbidities are often overlooked. We present a patient with depressive disorder resulting in suicide in a patient with NF1.
October 20, 2017: Orbit
https://www.readbyqxmd.com/read/29039102/analysis-of-pro-inflammatory-cytokine-and-type-ii-interferon-induction-by-nanoparticles
#2
Timothy M Potter, Barry W Neun, Jamie C Rodriguez, Anna N Ilinskaya, Marina A Dobrovolskaia
Cytokines, chemokines, and interferons are released by the immune cells in response to cellular stress, damage and/or pathogens, and are widely used as biomarkers of inflammation. Certain levels of cytokines are needed to stimulate an immune response in applications such as vaccines or immunotherapy where immune stimulation is desired. However, undesirable elevation of cytokine levels, as may occur in response to a drug or a device, may lead to severe side effects such as systemic inflammatory response syndrome or cytokine storm...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28987135/non-coeliac-gluten-or-wheat-sensitivity-emerging-disease-or-misdiagnosis
#3
REVIEW
Michael DE Potter, Marjorie M Walker, Nicholas J Talley
Non-coeliac gluten or wheat sensitivity (NCG/WS) is a condition characterised by adverse gastrointestinal and/or extra-intestinal symptoms associated with the ingestion of gluten- or wheat-containing foods, in the absence of coeliac disease or wheat allergy. Up to one in 100 people in Australia may have coeliac disease but many more report adverse gastrointestinal and/or extra-intestinal symptoms after eating wheat products. In the absence of validated biomarkers, a diagnosis of NCG/WS can only be made by a double-blind, placebo-controlled, dietary crossover challenge with gluten, which is difficult to apply in clinical practice...
August 4, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/28977052/impact-of-paclitaxel-eluting-balloons-compared-to-second-generation-drug-eluting-stents-for-of-in-stent-restenosis-in-a-primarily-acute-coronary-syndrome-population
#4
Guillaume Marquis-Gravel, Alexis Matteau, Brian J Potter, François Gobeil, Nicolas Noiseux, Louis-Mathieu Stevens, Samer Mansour
BACKGROUND: The place of drug-eluting balloons (DEB) in the treatment of in-stent restenosis (ISR) is not well-defined, particularly in a population of all-comers with acute coronary syndromes (ACS). OBJECTIVE: Compare the clinical outcomes of DEB with second-generation drug-eluting stents (DES) for the treatment of ISR in a real-world population with a high proportion of ACS. METHODS: A retrospective analysis of consecutive patients with ISR treated with a DEB compared to patients treated with a second-generation DES was performed...
October 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28972891/executive-control-erp-and-pro-inflammatory-activity-in-emotionally-exhausted-middle-aged-employees-comparison-between-subclinical-burnout-and-mild-to-moderate-depression
#5
Patrick D Gajewski, Sylvia Boden, Gabriele Freude, Guy G Potter, Maren Claus, Peter Bröde, Carsten Watzl, Stephan Getzmann, Michael Falkenstein
Burnout is a syndrome occurring mainly in individuals with long-term stressful work. The main complaints are emotional exhaustion and reduced performance. Burnout also largely overlaps with depression. Both are characterized by increased incidence of infections due to dysregulation of the immune system, overexpression of pro-inflammatory cytokines and cognitive deficits, particularly related to executive functions. To distinguish between burnout and depression already at the pre-clinical stage, the present double-blinded study compared immunological and cognitive parameters in seventy-six employees from emotionally demanding occupations who were post-hoc subdivided into two groups scoring low (EE-) and high (EE+) in emotional exhaustion and low (DE-) and high (DE+) in depression...
December 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28882786/exosomal-biomarkers-in-down-syndrome-and-alzheimer-s-disease
#6
REVIEW
Eric D Hamlett, Aurélie Ledreux, Huntington Potter, Heidi J Chial, David Patterson, Joaquin M Espinosa, Brianne M Bettcher, Ann-Charlotte Granholm
Every person with Down syndrome (DS) has the characteristic features of Alzheimer's disease (AD) neuropathology in their brain by the age of forty, and most go on to develop AD dementia. Since people with DS show highly variable levels of baseline function, it is often difficult to identify early signs of dementia in this population. The discovery of blood biomarkers predictive of dementia onset and/or progression in DS is critical for developing effective clinical diagnostics. Our recent studies show that neuron-derived exosomes, which are small extracellular vesicles secreted by most cells in the body, contain elevated levels of amyloid-beta peptides and phosphorylated-Tau that could indicate a preclinical AD phase in people with DS starting in childhood...
September 4, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/28860867/doege-potter-syndrome-cause-of-nonislet-cell-tumor-hypoglycemia-the-first-case-report-from-nepal
#7
Vivek Pant, Suman Baral, Gita Sayami, Prakash Sayami
Doege-Potter syndrome (DPS), a paraneoplastic syndrome, presents as a hypoinsulinemic hypoglycemia from the ectopic secretion of insulin-like growth factor II from a solitary fibrous tumor which may be intrapleural or extrapleural in origin. We report a case of severe hypoglycemia in a 70-year old female initially admitted for resection of left sided solitary fibrous tumor of pleura. Investigation revealed true hypoglycemia, and DPS was diagnosed. The tumor was completely resected, after which no further hypoglycemic episodes were seen in 2 years follow-up...
2017: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/28822226/perinatal-outcomes-after-previable-preterm-premature-rupture-of-membranes-before-24-weeks-of-gestation
#8
Verena Kiver, Vinzenz Boos, Anke Thomas, Wolfgang Henrich, Alexander Weichert
OBJECTIVE: A current descriptive assessment of perinatal outcomes in pregnancies complicated by previable preterm premature rupture of membranes (pPPROM) at <24 weeks of gestation, after expectant treatment. STUDY DESIGN: Maternal and short-term neonatal data were collected for patients with pPPROM. RESULTS: Seventy-three patients with 93 fetuses were hospitalized with pPPROM at 15-24 weeks' gestation. Among these patients, 27.4% (n=20) chose pregnancy termination, 27...
August 19, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28682900/doege-potter-syndrome-a-review-of-the-literature-including-a-new-case-report
#9
REVIEW
Guiyan Han, Zhimin Zhang, Xingbin Shen, Kunpeng Wang, Yang Zhao, Jianqiu He, Yu Gao, Xiujie Shan, Guohua Xin, Chunhui Li, Xiaoyan Liu
RATIONALE: We reviewed 76 published cases of Doege-Potter syndrome, and non-islet cell tumor hypoglycemia (NICTH) secondary to a solitary fibrous tumor (SFT) between 1989 and 2016, to study disease pathogenesis, diagnosis, and treatment of this rare paraneoplastic disease. Further, we report 1 new case of a patient presenting with Doege-Potter syndrome. PATIENTS CONCERNS: The tumors originated from the pleural cavity, lung, pelvis, liver, retroperitoneum, kidney, mediastinal, the sella, uterus, bladder, intestine, mandibular, and the thigh...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28593624/-the-othello-syndrome-in-parkinson-s-disease-an-example-of-a-lesser-known-delusion
#10
E C Potters, J T H van Asseldonk, J J D Tilanus
Delusions are fairly common features of Parkinson's disease. Some delusions are easily recognised, but others are less well-known and can be missed by health professionals. We describe the case of a female patient with Parkinson's disease who believed, erroneously, that her partner was being unfaithful; this type of delusion is also called the Othello syndrome. After psychoeducation and the start of clozapine, the delusion faded and the relationship became more peaceful.
2017: Tijdschrift Voor Psychiatrie
https://www.readbyqxmd.com/read/28573425/night-eating-syndrome-and-its-association-with-weight-status-physical-activity-eating-habits-smoking-status-and-sleep-patterns-among-college-students
#11
Najat Yahia, Carrie Brown, Stacey Potter, Hailey Szymanski, Karen Smith, Lindsay Pringle, Christine Herman, Manuela Uribe, Zhuxuan Fu, Mei Chung, Allan Geliebter
BACKGROUND: Night eating syndrome (NES) is characterized by evening hyperphagia and/or nocturnal ingestion. OBJECTIVE: The main objective of this study was to assess the percentage of students complying with symptoms and behaviors consistent with the diagnostic criteria for NES, and explore its association with body mass index (BMI), dietary habits, physical activity, smoking status, and sleep patterns, among a sample of college students. METHODS: A cross-sectional survey was conducted among a sample of 413 undergraduate students, mean age of 20...
June 2, 2017: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/28523334/large-pleural-tumor-revealed-by-severe-hypoglycemia-doege-potter-syndrome
#12
Irina Ruxandra Strâmbu, Diana Gabriela Leonte, Ciprian Nicolae Bolca
AIM: Doege-Potter syndrome is a rare condition consisting of a mesenchymal tumor, either benign or malignant, accompanied by severe hypoglycemia. The syndrome was first described independently by two American physicians, Karl Walter Doege (1867-1932) and Roy Pilling Potter (1879-1968), in 1930, but it was not before 1988 that it was associated with non-islet cell tumor production of insulin growth factor (IGF) that induces hypoglycemia as a paraneoplastic syndrome. CASE PRESENTATION: We present the case of a 61-year-old woman with severe hypoglycemia that induced seizures...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28504915/prevalence-of-os-styloideum-in-national-hockey-league-players
#13
Harry G Greditzer, Ian D Hutchinson, Christian S Geannette, Robert N Hotchkiss, Bryan T Kelly, Hollis G Potter
BACKGROUND: Os styloideum describes an accessory carpal ossicle between the trapezoid, the capitate, and the second and third metacarpals. Injuries to this tissue have been described as part of the carpal boss syndrome. While the etiology of os styloideum remains uncertain, it may represent a physiologic response to altered loading forces in the wrist, similar to the development of cam-type deformity in the hips of ice hockey players or the Bennett lesion in the shoulders of baseball pitchers...
September 2017: Sports Health
https://www.readbyqxmd.com/read/28453880/predicting-postnatal-renal-function-of-prenatally-detected-posterior-urethral-valves-using-fetal-diffusion-weighted-magnetic-resonance-imaging-with-apparent-diffusion-coefficient-determination
#14
Alice Faure, Nicoleta Panait, Michel Panuel, Pierre Alessandrini, Claude D'Ercole, Kathia Chaumoitre, Thierry Merrot
OBJECTIVE: The objective of this study was to evaluate the accuracy of fetal diffusion-weighted magnetic resonance imaging with apparent diffusion coefficient (ADC) determination to predict postnatal renal function (nadir creatinine at 1 year and eGFR) of men with posterior urethral valves (PUV). METHODS: Between 2003 and 2014, 11 MRI were performed on fetuses (between 28 and 32 weeks) in whom second trimester sonography suggested severe bilateral urinary tract anomalies, suspected of PUV...
July 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28410845/-paraneoplastic-hypoglycemia-the-hopes-of-pathophysiological-documentation
#15
A Villemain, O Menard, D Mandry, J Siat, J-M Vignaud, Y Martinet, A Tiotiu
Doege-Potter syndrome is a paraneoplastic syndrome characterized by non-islet cell tumor hypoglycemia secondary to a solitary fibrous tumor. These tumors are rare and usually asymptomatic. The syndrome of hypoglycemia is seen in less than 5% of the cases, and the associated tumors are large with a high mitotic rate. The cause of hypoglycemia is related to insulin-like growth factors produced by these tumors called "big" IGF-2. Several biological tests can demonstrate the increase of "big" IGF-2 plasma levels confirming the diagnosis of non-islet cell tumor induced hypoglycemia...
April 11, 2017: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/28341786/effectiveness-of-foot-fasciotomies-in-foot-and-ankle-trauma
#16
Katherine M Bedigrew, D J Stinner, J F Kragh, B K Potter, S B Shawen, J R Hsu
BACKGROUND: Foot compartment syndrome (FCS) has been reported to cause neuropathic pain, claw or hammer toes, and motor and sensory disturbances. The optimal treatment of FCS is controversial. The purpose of this study was to determine if foot fasciotomies improve patient outcomes in high-energy, combat-related lower extremity trauma. METHODS: Medical records of patients with documented FCS from May 2007 to January 2009 were retrospectively reviewed. Consecutive, matched control patients were identified based on similar hindfoot, mid-foot and/or forefoot injuries who did not undergo foot fasciotomy during the same period...
October 2017: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/28228892/metastatic-extrapleural-malignant-solitary-fibrous-tumor-presenting-with-hypoglycemia-doege-potter-syndrome
#17
Andrew J Degnan, Kenneth K W Lee, Marta I Minervini, Amir A Borhani
We report a rare case of metastatic malignant solitary fibrous tumor (SFT) that presented with hypoglycemia because of insulin growth factor-2 production. Initial workup included computed tomography imaging that revealed a large, partially necrotic liver mass, a hypervascular pancreatic head lesion, and 2 renal lesions. Following hepatic resection, pancreatic head resection and nephrectomy, all these lesions demonstrated pathological findings that were consistent with SFT. The patient also had a history of an intracranial mass that had been previously resected and treated with gamma knife therapy at an outside institution, which was found to also be SFT...
March 2017: Radiology case reports
https://www.readbyqxmd.com/read/28202406/cannabis-cultivation-methodological-issues-for-obtaining-medical-grade-product
#18
REVIEW
Suman Chandra, Hemant Lata, Mahmoud A ElSohly, Larry A Walker, David Potter
As studies continue to reveal favorable findings for the use of cannabidiol in the management of childhood epilepsy syndromes and other disorders, best practices for the large-scale production of Cannabis are needed for timely product development and research purposes. The processes of two institutions with extensive experience in producing large-scale cannabidiol chemotype Cannabis crops-GW Pharmaceuticals and the University of Mississippi-are described, including breeding, indoor and outdoor growing, harvesting, and extraction methods...
February 12, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28126075/melkersson-rosenthal-syndrome-presenting-as-isolated-eyelid-edema
#19
Devasis N Reddy, Jacob S Martin, Heather D Potter
No abstract text is available yet for this article.
February 2017: Ophthalmology
https://www.readbyqxmd.com/read/28112700/a-case-of-solitary-fibrous-pleura-tumor-associated-with-severe-hypoglycemia-the-doege-potter-s-syndrome
#20
Silvia Haddoub, L Gnetti, A Montanari, R Di Ruvo, P Carbognani, F Maccanelli, M G Magotti, M C Calderini, Federico Cioni, S M Tardio
Solitary fibrous pleura tumor is a rare primary intrathoracic tumor of the pleura. It usually has an indolent clinical course, but sometimes it can have an aggressive behaviour. In 1930 Doege and Potter independently described this neoplasm, presenting with symptoms of hypoglycemia, hence the eponim of Doege-Potter's Syndrome. In this report, we illustrate a case of Doege Potter's Syndrome, treated with complete surgical resection.
January 16, 2017: Acta Bio-medica: Atenei Parmensis
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