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potter syndrome

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https://www.readbyqxmd.com/read/28228892/metastatic-extrapleural-malignant-solitary-fibrous-tumor-presenting-with-hypoglycemia-doege-potter-syndrome
#1
Andrew J Degnan, Kenneth K W Lee, Marta I Minervini, Amir A Borhani
We report a rare case of metastatic malignant solitary fibrous tumor (SFT) that presented with hypoglycemia because of insulin growth factor-2 production. Initial workup included computed tomography imaging that revealed a large, partially necrotic liver mass, a hypervascular pancreatic head lesion, and 2 renal lesions. Following hepatic resection, pancreatic head resection and nephrectomy, all these lesions demonstrated pathological findings that were consistent with SFT. The patient also had a history of an intracranial mass that had been previously resected and treated with gamma knife therapy at an outside institution, which was found to also be SFT...
March 2017: Radiology case reports
https://www.readbyqxmd.com/read/28202406/cannabis-cultivation-methodological-issues-for-obtaining-medical-grade-product
#2
REVIEW
Suman Chandra, Hemant Lata, Mahmoud A ElSohly, Larry A Walker, David Potter
As studies continue to reveal favorable findings for the use of cannabidiol in the management of childhood epilepsy syndromes and other disorders, best practices for the large-scale production of Cannabis are needed for timely product development and research purposes. The processes of two institutions with extensive experience in producing large-scale cannabidiol chemotype Cannabis crops-GW Pharmaceuticals and the University of Mississippi-are described, including breeding, indoor and outdoor growing, harvesting, and extraction methods...
February 12, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28126075/melkersson-rosenthal-syndrome-presenting-as-isolated-eyelid-edema
#3
Devasis N Reddy, Jacob S Martin, Heather D Potter
No abstract text is available yet for this article.
February 2017: Ophthalmology
https://www.readbyqxmd.com/read/28112700/a-case-of-solitary-fibrous-pleura-tumor-associated-with-severe-hypoglycemia-the-doege-potter-s-syndrome
#4
Silvia Haddoub, L Gnetti, A Montanari, R Di Ruvo, P Carbognani, F Maccanelli, M G Magotti, M C Calderini, Federico Cioni, S M Tardio
Solitary fibrous pleura tumor is a rare primary intrathoracic tumor of the pleura. It usually has an indolent clinical course, but sometimes it can have an aggressive behaviour. In 1930 Doege and Potter independently described this neoplasm, presenting with symptoms of hypoglycemia, hence the eponim of Doege-Potter's Syndrome. In this report, we illustrate a case of Doege Potter's Syndrome, treated with complete surgical resection.
January 16, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/28109372/lessons-learned-from-an%C3%A2-untreated-benign-thoracic%C3%A2-tumor
#5
Laura A Scrimgeour, Zakaria Grada, Bassam I Aswad, Thomas Ng
We describe a patient with Doege-Potter syndrome (solitary fibrous tumor of the pleura presenting with hypoglycemia) and illustrate several important lessons learned from the case. Seven years after the initial diagnosis, the tumor showed significant growth and developed a high-grade undifferentiated component. Solitary fibrous tumors do grow and cannot be deemed benign. Resection should be considered in all patients who are candidates for operation upon diagnosis. Our case also serves as a reminder of this rare syndrome, inasmuch as early recognition of the association of hypoglycemia with these tumors may have allowed for earlier diagnosis and avoidance of extensive tests in our patient...
February 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28087518/cardiovascular-function-in-male-and-female-jcr-la-cp-rats-effect-of-high-fat-high-sucrose-diet
#6
Ian Hunter, Amanda Soler, Gregory Joseph, Brenda Hutcheson, Chastity Bradford, Frank Zhang, Barry J Potter, Spencer D Proctor, Petra Rocic
30% of the world population is diagnosed with metabolic syndrome. High fat/high sucrose diet (HF/HS, Western diet) correlates with metabolic syndrome prevalence. We characterized effects of the HF/HS diet on vascular (arterial stiffness, vasoreactivity, coronary collateral development) and cardiac (echocardiography) function, oxidative stress and inflammation in a rat model of metabolic syndrome (JCR). Furthermore, we determined whether male vs. female animals were affected differentially by the Western diet...
January 13, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/28075222/expression-of-myd88-in-adipose-tissue-of-obese-people-is-there-some-role-in-the-development-of-metabolic-syndrome
#7
Ada M Cuevas, Mariana Lazo, Isabel Zuñiga, Fernando Carrasco, Jim J Potter, Veronica Alvarez, Marcos Berry, Fernando Maluenda, Mario Ferrario, Jeanne M Clark
BACKGROUND: The mechanism leading to the development of metabolic complications in obese individuals is not fully understood. Thus, the objective of this study was to examine differences in insulin resistance, inflammation, cytokine and adipokine levels, and expression of selected genes across obese individuals with different number of metabolic syndrome (MetS) components. METHODS: Forty obese individuals who underwent bariatric surgery, divided in three groups based on the number of components of MetS, in addition to abdominal obesity (0, 1, and 2-3 additional components), were studied...
January 11, 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/28060156/defining-low-cardiac-output-syndrome-an-ode-to-justice-potter-stewart
#8
Jeffrey A Alten, Michael Gaies
No abstract text is available yet for this article.
January 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27994858/renal-tubular-dysgenesis-antenatal-ultrasound-scanning-and-molecular-investigations-in-a-saudi-arabian-family
#9
Mohamed H Al-Hamed, Wesam Kurdi, Nada Alsahan, Qaamariya Ambosaidi, Maha Tulbah, John A Sayer
Autosomal recessive renal tubular dysgenesis (RTD) is a rare lethal disease affecting renal development before birth. RTD is manifested by anuria and severe hypotension resulting in oligohydramnios and birth defects known as Potter's syndrome. Homozygous or compound heterozygous mutations in genes encoding components of the renin-angiotensin system (ACE, AGT, AGTR1 and REN) have been reported to cause RTD. A consanguineous family with a history of multiple stillbirths was investigated using prenatal ultrasound and molecular genetic analysis of an affected foetus...
December 2016: Clinical Kidney Journal
https://www.readbyqxmd.com/read/27932370/doege-potter-syndrome-hypoglycaemic-coma-in-a-90-year-old-due-to-a-solitary-fibrous-tumour
#10
Alla Avramenko, Hayat Lahjibi-Paulet, Laure Gibault, Arnaud Roussel, Bertrand Grand, Françoise Le Pimpec-Barthes
Solitary fibrous tumour of the pleura (SFTP) is a rare primary tumour of the pleura associated with 4% of cases with a paraneoplastic hypoglycaemia, termed Doege-Potter syndrome (DPS). We report a case of DPS presenting with severe coma in a 90-year-old woman. The cause was a malignant SFTP treated with surgical resection, from which the patient made a full recovery with prevention of recurrent hypoglycaemia. Surgical resection of the SFTP presenting with symptomatic hypoglycaemia should be considered even in elderly patients...
December 7, 2016: Age and Ageing
https://www.readbyqxmd.com/read/27780745/cross-sectional-study-of-high-sensitivity-cardiac-troponins-t-and-i-in-a-hospital-and-community-outpatient-setting
#11
Julia M Potter, Aaron J Simpson, Jennifer Kerrigan, Emma Southcott, Marie M Salib, Gus Koerbin, Peter E Hickman
OBJECTIVES: Cardiac troponins are specific for the heart, but not for the acute coronary syndrome. We wanted to assess how common elevated cardiac troponin concentrations were, in a population with significant non-cardiac disease. DESIGN & METHODS: We measured both hs-cTnT and hs-cTnI on all samples submitted to the laboratory during one 24h period, and assessed the magnitude of the cTn concentration with the location and severity of disease of the patient. RESULTS: Community patients and patients from the maternity ward had the lowest cTn concentrations with results above the 99th percentile being only 0-2% of the total...
February 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/27723620/-doege-potter-syndrome
#12
Alicia Pitrella, Andrés Domínguez, Walter Camus, Maximiliano Nocetti, Iván Boroni
No abstract text is available yet for this article.
2016: Medicina
https://www.readbyqxmd.com/read/27376978/solitary-fibrous-tumor-of-the-pleura-with-associated-doege-potter-syndrome
#13
J Reinder D Reuvers, Martijn van Dorp, Paul E Van Schil
Doege-Potter syndrome is a paraneoplastic syndrome characterized by tumor-associated hypoglycemia secondary to a solitary fibrous tumor of the pleura. We present a case of an 84-year-old man, who presented with acute mental confusion and therapy-resistant hypoglycemia. Diagnostic imaging revealed a large sharply defined pleural tumor based on the left diaphragm, after surgical resection the diagnosis was made of a malignant solitary fibrous tumor of the pleura and restoration of the glucose homeostasis was observed...
December 2016: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/27264633/comparison-of-intensive-chemotherapy-and-hypomethylating-agents-before-allogeneic-stem-cell-transplantation-for-advanced-myelodysplastic-syndromes-a-study-of-the-myelodysplastic-syndrome-subcommittee-of-the-chronic-malignancies-working-party-of-the-european
#14
Victoria T Potter, Simona Iacobelli, Anja van Biezen, Johann Maertens, Jean-Henri Bourhis, Jakob R Passweg, Ibrahim Yakhoub-Agha, Reza Tabrizi, Jacques-Olivier Bay, Patrice Chevallier, Yves Chalandon, Anne Huynh, Jean Yves Cahn, Per Ljungman, Charles Craddock, Stig Lenhoff, N H Russell, Nathalie Fegueux, Gerard Socié, Bruno Benedetto, Ellen Meijer, G J Mufti, Theo de Witte, Marie Robin, Nicolaus Kröger
The European Society for Blood and Marrow Transplant Research data set was used to retrospectively analyze the outcomes of hypomethylating therapy (HMA) compared with those of conventional chemotherapy (CC) before hematopoietic stem cell transplantation (HSCT) in 209 patients with advanced myelodysplastic syndromes. Median follow-up was 22.1 months and the median age of the group was 57.6 years with 37% of the population older than > 60 years. The majority of patients (59%) received reduced-intensity conditioning and 34% and 27% had intermediate-2 and high international prognostic scoring system (IPSS) scores...
September 2016: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/27193136/an-evidence-based-resource-for-the-management-of-comorbidities-associated-with-childhood-overweight-and-obesity
#15
REVIEW
Nicole Thompson, Bobbe Mansfield, Meredith Stringer, Brandy Stewart, Jami Potter, Karen Fernengel
PURPOSE: Overweight and obesity in children and adolescents is often accompanied by obesity-related comorbidities. An integrative review of the literature was performed to create a comprehensive algorithm to help primary care providers manage the common comorbidities associated with childhood overweight and obesity. DATA SOURCES: The Cumulative Index to Nursing and Allied Health Literature, ProQuest Nursing and Allied Health Source, and PubMed databases were searched...
October 2016: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/27153221/parental-origin-of-interstitial-duplications-at-15q11-2-q13-3-in-schizophrenia-and-neurodevelopmental-disorders
#16
Anthony R Isles, Andrés Ingason, Chelsea Lowther, James Walters, Micha Gawlick, Gerald Stöber, Elliott Rees, Joanna Martin, Rosie B Little, Harry Potter, Lyudmila Georgieva, Lucilla Pizzo, Norio Ozaki, Branko Aleksic, Itaru Kushima, Masashi Ikeda, Nakao Iwata, Douglas F Levinson, Pablo V Gejman, Jianxin Shi, Alan R Sanders, Jubao Duan, Joseph Willis, Sanjay Sisodiya, Gregory Costain, Thomas M Werge, Franziska Degenhardt, Ina Giegling, Dan Rujescu, Stefan J Hreidarsson, Evald Saemundsen, Joo Wook Ahn, Caroline Ogilvie, Santhosh D Girirajan, Hreinn Stefansson, Kari Stefansson, Michael C O'Donovan, Michael J Owen, Anne Bassett, George Kirov
Duplications at 15q11.2-q13.3 overlapping the Prader-Willi/Angelman syndrome (PWS/AS) region have been associated with developmental delay (DD), autism spectrum disorder (ASD) and schizophrenia (SZ). Due to presence of imprinted genes within the region, the parental origin of these duplications may be key to the pathogenicity. Duplications of maternal origin are associated with disease, whereas the pathogenicity of paternal ones is unclear. To clarify the role of maternal and paternal duplications, we conducted the largest and most detailed study to date of parental origin of 15q11...
May 2016: PLoS Genetics
https://www.readbyqxmd.com/read/27134683/seborrheic-keratoses-and-severe-hypoinsulinemic-hypoglycemia-associated-with-insulin-grow-factor-2-secretion-by-a-malignant-solitary-fibrous-tumor
#17
Andreia Latanza Gomes Mathez, Debora Moroto, Sergio Atala Dib, Joao Roberto de Sa
A rare sign of some malignant tumors is a sudden eruption of multiple seborrheic keratoses called Leser-Trélat sign. Overproduction of insulin-like growth factor-2 (IGF2) or its precursor is the main mechanism related to non-islet cell tumor hypoglycemia. Doege-Potter syndrome is the name given to paraneoplastic hypoinsulinemic hypoglycemia in presence of a solitary fibrous tumor. This report describes a case of a patient with hypoinsulinemic hypoglycemia and Leser-Trélat sign associated with a malignant solitary fibrous tumor with IGF2 secretion...
2016: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/27066327/dermatoglyphics-in-kidney-diseases-a-review
#18
REVIEW
Buddhika T B Wijerathne, Robert J Meier, Sujatha S Salgado, Suneth B Agampodi
Kidney diseases are becoming a major cause of global burden with high mortality and morbidity. The origins of most kidney diseases are known, but for some the exact aetiology is not yet understood. Dermatoglyphics is the scientific study of epidermal ridge patterns and it has been used as a non-invasive diagnostic tool to detect or predict different medical conditions that have foetal origin. However, there have been a limited number of studies that have evaluated a dermatoglyphic relationship in different kidney diseases...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27063605/multivitamin-calcium-and-folic-acid-supplements-and-the-risk-of-colorectal-cancer-in-lynch-syndrome
#19
Rowena Chau, Seyedeh Ghazaleh Dashti, Driss Ait Ouakrim, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Joanne P Young, Graham G Giles, Finlay A Macrae, Alex Boussioutas, Susan Parry, Jane C Figueiredo, A Joan Levine, Dennis J Ahnen, Graham Casey, Robert W Haile, Steven Gallinger, Loïc Le Marchand, Stephen N Thibodeau, Noralane M Lindor, Polly A Newcomb, John D Potter, John A Baron, John L Hopper, Mark A Jenkins, Aung Ko Win
BACKGROUND: People with a DNA mismatch repair (MMR) gene mutation have a substantially elevated risk of colorectal cancer (CRC) but the modifiers of this risk are not well established. We investigated the association between dietary supplement intake and CRC risk for carriers. METHODS: This study included 1966 (56% female) carriers of an MMR gene mutation (719 MLH1, 931 MSH2, 211 MSH6 and 105 PMS2) who were recruited from the USA, Canada, Australia and New Zealand into the Colon Cancer Family Registry between 1997 and 2012...
June 2016: International Journal of Epidemiology
https://www.readbyqxmd.com/read/27017362/-loeys-dietz-syndrome-tgf%C3%AE-r2%C3%A2-mutation-in-a-4-year-old-child-with-thoracic-aortic-aneurysm
#20
M-J De Potter, T Edouard, R Amadieu, J Plaisancié, S Julia, K Hadeed, S Hascoët, P Acar, Y Dulac
Loeys-Dietz syndrome is a rare form of connective tissue disorder, whose clinical features can resemble those of Marfan syndrome, but with a more unpolished appearance. Recently brought out, this pathology remains little known; however, its consequences may be dramatic. We report on the case of a 4-year-old girl followed for a congenital hip dislocation, in which a systematic exam found increased cutaneous elasticity and a bifid uvula, suggesting a connective tissue disorder. Symptoms were unpolished, as the child's height was normal, without any positive cardiac, rheumatological, or ophthalmological family history...
May 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
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