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Stefan Reuter, Stefanie Reiermann, Viola Malyar, Katharina Schütte-Nütgen, Renè Schmidt, Hermann Pavenstädt, Holger Reinecke, Barbara Suwelack
BACKGROUND: Cardiovascular disease (CVD) is the leading cause of death after renal transplantation with a high prevalence in dialysis patients. It is still a matter of debate how to assess the cardiovascular risk in kidney transplant candidates. Several approaches and scores exist and found their way into the guidelines. METHODS AND RESULTS: We herein assessed PROCAM, Framingham, ESC-SCORE and our own dedicated algorithm in patients applying for renal transplantation at our transplantation center between July 2006 and August 2009...
2016: PloS One
Wenzel Schoening, Niklas Buescher, Nadja Neidel, Michael Helbig, Andreas Andreou, Andreas Pascher, Marcus Bahra, Johann Pratschke, Daniel Seehofer
BACKGROUND: Cardio- and cerebrovascular diseases are the third leading cause of late death after liver transplantation (LT). A new score (PROCAM-Stroke) has been established to estimate the 10-year risk of cerebrovascular events (CBVE) in a German standard population. We evaluate the applicability of the PROCAM-Stroke for long-term follow-up after LT. PATIENTS AND METHODS: A retrospective study of 313 consecutive LTs was conducted. Six months after LT (T1) and 10 years after LT (T2), CBVE risk factors were recorded and PROCAM-Stroke was calculated...
October 2016: Clinical Transplantation
K Kempf, S Martin, C Döhring, K Dugi, B Haastert, M Schneider
BACKGROUND: Cardiovascular disease (CVD) may cause an economic burden to companies, but CVD risk estimations specific to working populations are lacking. AIMS: To estimate the 10-year CVD risk in the Boehringer Ingelheim (BI) employee cohort and analyse the potential effect of hypothetical risk reduction interventions. METHODS: We estimated CVD risk using the Framingham (FRS), PROCAM (PRS) and Reynolds (RRS) risk scores, using cross-sectional baseline data on BI Pharma employees collected from 2005 to 2011...
October 2016: Occupational Medicine
Carole E Aubert, Baris Gencer, Nicolas Rodondi
Discordance between American guidelines and the "Swiss medical Board" position regarding treatment of dyslipidemia raised many questions. While benefits of statins are clear in secondary prevention, care should be individualised according to PROCAM cardiovascular risk score adapted to Switzerland in primary prevention. Lifestyle modification should be the first line therapy and a drug therapy is an option in high or intermediate risk, but not anymore in low cardiovascular risk. Familial dyslipidemia, often identified only after first cardiovascular event, should not be missed, as particular care is needed and riskscores cannot be used in this situation...
March 2, 2016: Revue Médicale Suisse
Patricia Lister-Del Pino, Gustavo León-Amenero, Angela Leiva-Montejo, Eddy R Segura
OBJECTIVES: The aim of the study is to determine the concordance between the PROCAM (Prospective Cardiovascular Münster) and Framingham scales in patients receiving highly active antiretroviral therapy (HAART). MATERIALS AND METHODS: A cross sectional study was conducted in HIV-positive male population who use HAART in a national reference hospital located in Lima, Peru. To evaluate the concordance between the two scales the graphic method of Bland and Altman was used, for the evaluation of the correlation we used the Pearson coefficient and to measure the agreement we use the kappa coefficient...
October 2015: Revista Peruana de Medicina Experimental y Salud Pública
Ayfer Bayındır Çevik, Şeyda Özcan, İlhan Satman
PURPOSE: To determine the cardiovascular risk factors according to the Framingham, PROCAM and SCORE models, to evaluate the 10-year cardiovascular disease (CVD) risk factors, and to compare the suitability of different models in Turkish Type 2 diabetes patients. METHODS: Risk factors and the 10-year CVD risk in 265 patients were evaluated using three risk models. Measurements included blood pressure, weight, height, waist and hip circumferences. Cholesterol, triglycerides, fasting and postprandial plasma glucose and HbA1c were measured...
2015: Contemporary Nurse
Hatice Tolunay, Ozge Kurmus
BACKGROUND: Reliable risk scoring systems that can predict the severity of coronary artery disease (CAD) are necessary to implement effective management strategies in high-risk patients. Atherosclerotic vascular disease and with cardiovascular morbidity and mortality risk are patients who would benefit most from a change in patients at high risk factors. Framingham Risk Score, the Prospective Cardiovascular Münster (PROCAM) score and Systematic Coronary Risk Evaluation (SCORE) risk scores are used for this purpose...
2016: Cardiology Journal
Sigrun A Chrubasik, Cosima A Chrubasik, Jörg Piper, Juergen Schulte-Moenting, Paul Erne
INTRODUCTION: In models and scores for estimating cardiovascular risk (CVR), the relative weightings given to blood pressure measurements (BPMs), and biometric and laboratory variables are such that even large differences in blood pressure lead to rather low differences in the resulting total risk when compared with other concurrent risk factors. We evaluated this phenomenon based on the PROCAM score, using BPMs made by volunteer subjects at home (HBPMs) and automated ambulatory BPMs (ABPMs) carried out in the same subjects...
2015: Swiss Medical Weekly
P Antiochos, P Marques-Vidal, G Waeber, P Vollenweider
BACKGROUND AND AIMS: Data from prospective cohorts describing dyslipidaemia prevalence and treatment trends are lacking. Using data from the prospective CoLaus study, we aimed to examine changes in serum lipid levels, dyslipidaemia prevalence and management in a population-based sample of Swiss adults. METHODS AND RESULTS: Cardiovascular risk was assessed using PROCAM. Dyslipidaemia and low-density lipoprotein cholesterol (LDL-C) target levels were defined according to the Swiss Group for Lipids and Atherosclerosis...
November 2015: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
Niclas Freund, Bernhard C Friedli, Therese Junker, Martin Zimmermann, Michael J Zellweger
BACKGROUND: "CardioTest (®) " is a tool for cardiovascular risk assessment. The aim of this study was to evaluate if this test used in Swiss pharmacies provides risk stratification and if it had impact on individual behaviour. METHODS: Individuals were evaluated (blood pressure, body waist circumference, random blood samples and coronary artery disease risk factors). The cardiovascular risk was calculated (AGLA Risk Score (ARS) a modified PROCAM Score) and participants were informed about their result...
2015: Open Cardiovascular Medicine Journal
I Tsiflikas, C Thomas, C Fallmann, C Schabel, S Mangold, D Ketelsen, C D Claussen, D Axmann, S Schroeder, C Burgstahler
PURPOSE: To evaluate the prevalence of coronary artery disease (CAD) in middle-aged, male marathon runners using coronary dual source CT angiography (DSCTA). MATERIALS AND METHODS: 50 male marathon runners older than 45 years (mean age: 52.7, standard deviation: 5.9 years, range: 45 to 67 years) received DSCTA including calcium scoring (CS) in addition to standard pre-participation screening. Based on standard risk factors, the risk for coronary events was calculated using the PROCAM score...
July 2015: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
A Purcarea, S Sovaila, G Udrea, E Rezus, A Gheorghe, C Tiu, V Stoica
BACKGROUND: Rheumatoid arthritis comes with a 30% higher probability for cardiovascular disease than the general population. Current guidelines advocate for early and aggressive primary prevention and treatment of risk factors in high-risk populations but this excess risk is under-addressed in RA in real life. This is mainly due to difficulties met in the correct risk evaluation. This study aims to underline the differences in results of the main cardiovascular risk screening models in the real life rheumatoid arthritis population...
October 2014: Journal of Medicine and Life
Matthias Bossard, Katrin Pumpol, Stéphanie van der Lely, Stefanie Aeschbacher, Tobias Schoen, Philipp Krisai, Tschuenschen Lam, John Todd, Joel Estis, Martin Risch, Lorenz Risch, David Conen
OBJECTIVES: Endothelial dysfunction is a major precursor of atherosclerosis. The aim of this study was to assess the interrelationships between plasma endothelin-1 (ET-1) levels and cardiovascular risk among young and healthy individuals. METHODS: We performed a population-based study among 2160 healthy adults aged between 25 and 41 years in the Principality of Liechtenstein. Individuals with prevalent cardiovascular disease, diabetes or a body mass index >35 kg/m(2) were excluded...
March 2015: Atherosclerosis
Wenzel Schoening, Nadja Neidel, Niklas Buescher, Andreas Andreou, Andreas Pascher, Daniel Seehofer, Marcus Bahra, Volker Schmitz, Johann Pratschke, Gero Puhl
Cardiovascular diseases (CVD) are the third leading cause of late death after liver transplantation (LT). The old PROCAM score was described in males (aged 35-65 yr) to estimate cardiovascular events after LT. New PROCAM is now available to estimate risks for cardiovascular events in both genders and for a wider age range (25-75 yr). We tested old and new PROCAM in long-term follow-up (10 and 20 yr) and described CVD risk factors, kidney function, and immunosuppression over two decades. A retrospective study of 313 consecutive LTs was conducted...
April 2015: Clinical Transplantation
Johannes Wild, Mattia Arrigo, Bruno Dieter Isenring, Urs Buergi, Thomas Kurowski, Macé M Schuurmans, Lars C Huber, Christian Benden
BACKGROUND: An atherosclerotic disease burden sufficient to put lung transplant candidates at risk for end-organ disease after transplantation is considered to be a relative contraindication for lung transplantation. OBJECTIVES: The aim of this study was to assess our current practice of cardiac workup by coronary angiography in lung transplant candidates ≥50 years of age. METHODS: We retrospectively analyzed 50 consecutive lung transplant candidates ≥50 years of age in which coronary angiography was performed at the University Hospital Zurich (2009-2013)...
2015: Respiration; International Review of Thoracic Diseases
Alexander Karl-Georg Schuster, Joachim Ernst Fischer, Urs Vossmerbaeumer
BACKGROUND: Examination of retinal vasculature can be used to non-invasively quantify changes within the microvasculature of the human body and might be a predictor of cardiovascular disease. This study evaluates associations of the structure of the retinal vasculature with established risk factors for cardiovascular disease. METHODS: A cross-sectional study was performed in a working age population. Several systemic cardiovascular parameters were analyzed and PROCAM- and SCORE-risk estimates were calculated...
February 1, 2015: International Journal of Cardiology
Mateja Pirš, Borut Jug, Barbara Eržen, Mišo Šabović, Primož Karner, Mario Poljak, Janez Tomažič
INTRODUCTION: Traditional cardiovascular (CVD) risk assessment algorithms such as the Framingham Risk Score (FRS), Systematic Coronary Risk Evaluation (SCORE) and Prospective Cardiovascular Munster (PROCAM) were developed for general populations, their usefulness in HIV-infected population has not been confirmed. DAD algorithm was developed specifically for HIV-infected patients. The aim of our study was to evaluate the performance of risk assessment algorithms in HIV-infected population...
2014: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
Vishali Gupta, Reema Bansal, Amod Gupta, Anil Bhansali
BACKGROUND: Nonmydriatic digital imaging (NMDI) is ideal for screening diabetic retinopathy (DR), but its use in Indian eyes has not been evaluated. AIM: The aim was to evaluate the sensitivity and specificity of NMDI as a screening tool in detecting DR in Indian eyes. DESIGN: A prospective, nonrandomized, noncomparative, noninterventional study. MATERIALS AND METHODS: A total of 500 diabetic patients visiting the endocrinology clinic (September 2008-June 2010) underwent NMDI (Zeiss Procam), followed by routine dilated fundus photography (FP; Zeiss Visupac 450+) of 345° retinal fields (1) optic disc and macula, (2) superotemporal, and (3) nasal to optic disc...
August 2014: Indian Journal of Ophthalmology
Nevena Eremić Kojić, Mirjana Derić, Jadranka Dejanović
INTRODUCTION: This study was done in order to evaluate the effect of serum levels of total cholesterol, triglycerides, low-density lipoprotein-cholesterol and high-density lipoprotein-cholesterol on 10-year coronary heart disease risk distribution change. MATERIAL AND METHODS: This study included 110 subjects of both genders (71 female and 39 male), aged 29 to 73, treated at the Outpatient Department of Atherosclerosis Prevention, Centre for Laboratory Medicine, Clinical Centre Vojvodina...
July 2014: Medicinski Pregled
Daniel Gladwell, Thea Henry, Mark Cook, Ron Akehurst
BACKGROUND: Patients with resistant hypertension are at a high risk for developing serious cardiovascular events and renal complications. Catheter-based renal denervation (RDN) is a procedure with the potential to normalize systolic blood pressure (SBP). OBJECTIVE: The overall objective of the study was to estimate the cost effectiveness of RDN in the UK for patients with diagnosed resistant hypertension, expressed as a standard cost per quality-adjusted life-year (QALY) ratio...
December 2014: Applied Health Economics and Health Policy
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