Holger Cramer, Christoph Hohmann, Romy Lauche, Kyung-Eun Anna Choi, Nadia Schneider, Nico Steckhan, Florian Rathjens, Dennis Anheyer, Anna Paul, Christel von Scheidt, Thomas Ostermann, Elisabeth Schneider, Daniela A Koppold-Liebscher, Christian S Kessler, Gustav Dobos, Andreas Michalsen, Michael Jeitler
BACKGROUND: Lifestyle interventions, such as fasting, diet, and exercise, are increasingly used as a treatment option for patients with metabolic syndrome (MS). This study assesses the efficacy and safety of fasting followed by lifestyle modification in patients with MS compared to lifestyle modification only. METHODS: Single-blind, multicenter, parallel, randomized controlled trial in two German tertiary referral hospitals in metropolitan areas. INTERVENTIONS: (a) 5-day fasting followed by 10 weeks of lifestyle modification (modified DASH diet, exercise, mindfulness; n = 73); (b) 10 weeks of lifestyle modification only ( n = 72)...
August 14, 2022: Journal of Clinical Medicine